CN114748408A - NMN-containing amino acid shower gel and preparation method thereof - Google Patents
NMN-containing amino acid shower gel and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention discloses NMN-containing amino acid shower gel and a preparation method thereof, and belongs to the technical field of cosmetics. The amino acid shower gel comprises the following components in parts by mass: 6-20% of amino acid surfactant, 2-10% of amphoteric surfactant, 0.5-5% of nonionic surfactant, 0.1-3% of NMN and 0.5-10% of honey extract. According to the invention, through reasonable matching of the surfactants, the amino acid shower gel which is mild, fine and rich in foam and appropriate in viscosity is formed, and the NMN and the honey extract are matched, so that the skin can be tender and smooth, moist and the like under reasonable matching. The shower gel disclosed by the invention is mild, clean, smooth and tender in skin through the synergistic effect of the components.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and relates to NMN-containing amino acid shower gel and a preparation method thereof.
Technical Field
The shower gel on the market is of a common type: one is a soap-based bath lotion and the other is a surfactant-based bath lotion. The soap-based shower gel mainly has the advantages that the shower gel can bring the experiences of refreshing feeling, clean feeling and rich foam to the human body, but the shower gel has strong degreasing capability, and can cause the uncomfortable feelings of dry and astringent skin, tightness and pruritus after frequent use. The mildness of the shower gel mainly comprising a surfactant is very different due to different surfactants, most of the shower gels of the prior surfactant type sold in the market mainly comprise AES (sodium laureth sulfate), the mildness of the shower gel is not good, and the shower gel is easy to stimulate the skin after being used every day, so that the problems of dry skin, pruritus, sensitivity and the like are caused.
The bathing product mainly containing the amino acid type surfactant is weakly acidic, is close to the pH value of a human body, has moderate decontamination capability, good skin-friendly property and low or almost no irritation, and is suitable for various crowds.
Along with the improvement of living standard and daily requirement of people, the shower gel is expected to make skin tender and smooth after long-term use besides the basic function of cleaning skin, and at present, products with the functions of the shower gel are not abundant in the market, and some frosted particles are usually added to achieve the function of tendering skin through physical friction, but the skin barrier can be damaged after long-term use, so that some skin problems are caused.
NMN, the standard chinese name for β -nicotinamide mononucleotide, is present in every living cell of the human body. NMN is an ultra-strong antioxidant, can remove free radicals in vivo, repair DNA, and can effectively tighten skin, improve skin moisture and make skin moist and smooth when being used in skin care products. At present, cosmetics use less NMN products.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the NMN-containing shower gel, and the amino acid shower gel which is mild, has exquisite and rich foam and proper viscosity is formed by reasonably matching the amino acid surfactant and other non-AES surfactants, and the NMN and honey extracts are matched, so that the skin can be tender, smooth and the like under the reasonable matching. The shower gel disclosed by the invention is mild and clean and has the effects of smoothing and tendering skin through the synergistic effect of the components.
The invention is realized by adopting the following technical scheme:
the NMN-containing amino acid shower gel comprises the following components in percentage by mass:
6-20% of amino acid surfactant, 2-10% of amphoteric surfactant, 0.5-5% of nonionic surfactant, 0.1-3% of NMN and 0.5-10% of honey extract.
Further, the NMN-containing amino acid shower gel comprises the following components in percentage by mass: 7-18% of amino acid surfactant, 2-8% of amphoteric surfactant, 1-4% of nonionic surfactant, 0.5-3% of NMN and 1-8% of honey extract.
Further, the NMN-containing amino acid shower gel comprises the following components in percentage by mass: 7-15% of amino acid surfactant, 3-7% of amphoteric surfactant, 1.5-3.5% of nonionic surfactant, 2-7% of NMN1 and 2-7% of honey extract.
Further, the NMN-containing amino acid shower gel is characterized in that the amino acid surfactant is sodium cocoamidopropionate.
Further, the NMN-containing amino acid shower gel comprises an amphoteric surfactant, wherein the amphoteric surfactant is one or more of sodium lauroamphoacetate, sodium cocoamphoacetate, lauramidopropyl betaine, cocamidopropyl betaine, cocamidohydroxysultaine and lauramidopropyl hydroxysultaine.
Further, the non-ionic surfactant is one or two of cocamide MEA and cocamide methyl MEA.
Further, an NMN-containing amino acid bath lotion is prepared by fermenting Mel extract with Gluconobacter at 15-40 deg.C and pH of 3.0-8.0, extracting the fermented Mel with 1, 3-butanediol, filtering, and centrifuging.
Further, the NMN-containing amino acid shower gel further comprises one or more of a preservative, a chelating agent, a pH regulator and deionized water.
Preferably, the preservative is a compound of p-hydroxyacetophenone and 1, 2-hexanediol to replace the traditional preservative.
Preferably, the preservative comprises, by mass, 0.3-0.8% of p-hydroxyacetophenone and 0.3-1.5% of 1, 2-hexanediol.
Preferably, the chelating agent is disodium EDTA.
Preferably, the chelating agent is 0.1-0.5% of EDTA disodium by mass percent.
Preferably, the pH regulator is citric acid, sodium citrate, lactic acid, sodium lactate, arginine.
Preferably, the pH regulator is citric acid or sodium citrate.
The invention also provides a preparation method of the NMN-containing amino acid shower gel, which comprises the following steps:
(1) putting deionized water, chelating agent, amino acid surfactant, amphoteric surfactant and nonionic surfactant into a stirring pot, heating to 80-85 ℃, and stirring for dissolving uniformly;
(2) heating p-hydroxyacetophenone and 1, 2-hexanediol in an auxiliary pot to dissolve the p-hydroxyacetophenone and the 1, 2-hexanediol to be transparent;
(3) cooling the stirred kettle to 60-65 ℃, slowly adding a transparent mixture of p-hydroxyacetophenone and 1, 2-hexanediol, and uniformly stirring and dissolving;
(4) cooling to 40-45 deg.C, adding NMN and Mel extract, stirring and dissolving;
(5) adding pH regulator to regulate pH of the paste (10% water solution) to 6-6.5;
(6) and filtering and discharging.
Drawings
FIG. 1: skin stratum corneum moisture test results.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
The technical solutions of the present invention are further illustrated by the following specific examples, which do not represent limitations to the scope of the present invention. Insubstantial modifications and adaptations of the present invention by others of the concepts fall within the scope of the invention.
Examples 1-3 an amino acid shower gel containing NMN
Table 1 an amino acid bath formula containing NMN
The preparation method comprises the following steps:
(1) putting the phase A raw material into a stirring pot, heating to 80-85 ℃, and uniformly stirring and dissolving;
(2) heating and dissolving the phase B raw material in an auxiliary pot to be transparent;
(3) cooling to 60-65 deg.C, slowly adding the B phase raw material, stirring and dissolving;
(4) cooling to 40-45 deg.C, adding C phase raw materials, stirring and dissolving;
(5) adding the phase D raw material, and adjusting the pH (10% water solution) of the paste to 6-6.5;
(6) and filtering and discharging.
Comparative example 1
The amount of sodium cocamidopropionate added in example 1 was changed to 5% with the other materials and preparation being unchanged.
Comparative example 2
The amount of sodium cocamidopropionate added in example 1 was changed to 22% with the other materials and preparation process unchanged.
Comparative example 3
The amount of cocamidopropyl betaine added in example 1 was changed to 1.5%, the other materials and the preparation process were unchanged.
Comparative example 4
The amount of cocamidopropyl betaine added in example 1 was changed to 12%, the other materials and the preparation process were unchanged.
Comparative example 5
The amount of cocamide methyl MEA added in example 1 was changed to 0.3%, and the other materials and preparation process were unchanged.
Comparative example 6
The amount of cocamide methyl MEA added in example 1 was changed to 6%, and the other materials and preparation process were unchanged.
Comparative example 7
The NMN in example 1 was removed and the other materials and preparation process were unchanged.
Comparative example 8
The honey extract of example 1 was removed and the other materials and preparation process were unchanged.
Comparative example 9
The NMN addition in example 1 was changed to 4%, and the other materials and preparation process were unchanged.
Comparative example 10
The honey extract without fermentation process was replaced with the honey extract of example 1, and the other materials and preparation process were unchanged.
Comparative example 11
The amount of honey extract added in example 1 was changed to 12%, and the other materials and preparation process were not changed.
Test 1 Patch test
The test substance: inventive examples 1-3, comparative examples 1-11.
The test method comprises the following steps: a proper spot sticking tester is selected, a closed spot sticking test method is adopted, a tested object is placed in the spot sticking tester, a special adhesive tape is externally applied to the back of a tested person, the tested object is removed after being applied for 24 hours, skin reactions are observed for 0.5 hour, 24 hours and 48 hours after the tested object is removed respectively, the results (0-4 respectively represent the number of adverse reaction grades, the larger the number is, the more serious the stimulation is represented) are recorded according to the skin reaction grading standard in the technical Specification for cosmetic safety (2015 edition), the grading grade is shown in a table 2, and the test result is shown in a table 3.
TABLE 2 skin response grading Standard for skin Enclosed Patch test
TABLE 3 test results of human skin patches
As can be seen from the patch test results, adverse reactions occurred in comparative examples 2, 4, 6, 9 and 11, and no adverse reaction occurred in the other test substances. The results show that amino acid surfactants, amphoteric surfactants and nonionic surfactants are added in amounts outside the scope of the invention and that NMN and honey extracts outside the scope of the invention cause different levels of irritation.
Test 2 human sensory test
The test substance: example 1, comparative examples 1,3, 5, 7, 8, 10.
The test method comprises the following steps: 210 volunteers are selected and randomly divided into 7 groups, 30 volunteers in each group use the test object according to the habit of daily using the shower gel, the foam richness, the product thickness satisfaction, the tenderness and smoothness and the water wettability of the test object are graded after 2 weeks of trial, the arithmetic mean value of each group is finally taken, and the test result is shown in table 4. The test result adopts a score of 5, and the score is from 5 to 1, and the test result is very satisfactory, relatively satisfactory, general, relatively unsatisfactory and very unsatisfactory in sequence.
TABLE 4 human sensory test Scoring results
| Test article | Richness of foam | Consistency satisfaction degree | Tender smoothness of | Degree of water wettability |
| Example 1 | 4.5 | 4.8 | 4.7 | 4.3 |
| Comparative example 1 | 2.8 | 3.6 | 4.5 | 4.5 |
| Comparative example 3 | 3.4 | 3.9 | 4.2 | 4.4 |
| Comparative example 5 | 4.3 | 2.6 | 4.4 | 4.5 |
| Comparative example 7 | 4.6 | 4.7 | 3.2 | 2.8 |
| Comparative example 8 | 4.5 | 4.5 | 2.6 | 3.1 |
| Comparative example 10 | 4.6 | 4.7 | 3.1 | 3.4 |
As can be seen from the results of human sensory tests, compared with comparative examples 1,3 and 5, the example 1 has obvious advantages in foam richness and thickness satisfaction indexes, and the results show that the reduction of the dosage of amino acid surfactant or amphoteric surfactant or nonionic surfactant, which is not in the scope of the invention, can cause insufficient foam, too thin (or too thick) paste and seriously affect the use feeling. Compared with comparative examples 7, 8 and 10, the embodiment 1 has obvious advantages in the indexes of tenderness and moisture, and the result shows that the NMN and the honey extract have synergistic effect, but the NMN and the honey extract have no effect, and can make the skin smooth and moist within a reasonable range.
Test 3 moisture retention Performance test
The test substance: examples 1 to 3, comparative examples 7, 8 and 10
The test method comprises the following steps: the testers washed their arms with 40 ℃ water using the bath cream of examples 1 to 3 and comparative examples 7, 8 and 10, wiped off after washing, the water content of the skin horny layer was measured for 0 hour, again for 4 hours in a constant temperature and humidity room, and again for 8 hours in a constant temperature and humidity room.
The moisture of the stratum corneum was tested using a skin moisture content test probe Corneometer CM 825. The results are shown in FIG. 1 (wherein the number of persons tested per group and the number of samples are 30, and the data are averaged).
As can be seen from the test results, the stratum corneum water content at 0h, 4h, 8h was greater for examples 1-3 than for comparative examples 7, 8, 10. The NMN-containing amino acid shower gel provided by the invention has good moisturizing performance, and the NMN and the honey extract have a synergistic effect, so that the skin is continuously moisturized and tender.
In conclusion, the amino acid bath cream containing the NMN provided by the invention is mild, fine and rich in foam and proper in viscosity through reasonable matching of the amino acid surfactant and other non-AES surfactants, and can make skin tender, moist and the like through reasonable matching by matching the NMN and the honey extract. The shower gel disclosed by the invention is mild and clean and has the effects of smoothing and tendering skin through the synergistic effect of the components.
The present invention has been described in further detail with reference to specific embodiments thereof, but the present invention is not limited thereto. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.
Claims (9)
1. The NMN-containing amino acid shower gel is characterized by comprising the following components in percentage by mass:
6-20% of amino acid surfactant, 2-10% of amphoteric surfactant, 0.5-5% of nonionic surfactant, 0.1-3% of NMN and 0.5-10% of honey extract.
2. The NMN-containing amino acid shower gel according to claim 1, comprising the following components in percentage by mass:
7-18% of amino acid surfactant, 2-8% of amphoteric surfactant, 1-4% of nonionic surfactant, 0.5-3% of NMN and 1-8% of honey extract.
3. The NMN-containing amino acid shower gel according to claim 1, comprising the following components in percentage by mass:
7-15% of amino acid surfactant, 3-7% of amphoteric surfactant, 1.5-3.5% of nonionic surfactant, 2-7% of NMN1 and 2-7% of honey extract.
4. An NMN-containing amino acid body wash according to claim 1, wherein the amino acid surfactant is sodium cocamidopropionate.
5. An NMN-containing amino acid body wash according to claim 1, wherein the amphoteric surfactant is one or more of sodium lauroamphoacetate, sodium cocoamphoacetate, lauramidopropyl betaine, cocamidopropyl betaine, cocamidohydroxysultaine, lauramidopropyl hydroxysultaine.
6. An NMN-containing amino acid body wash according to claim 1, wherein the non-ionic surfactant is one or both of cocamide MEA and cocamide methyl MEA.
7. An NMN-containing amino acid body wash as claimed in claim 1, wherein the honey extract is obtained by fermentation of Gluconobacter at 15-40 deg.C and pH 3.0-8.0, extraction of the honey after fermentation with 1, 3-butanediol, filtration and centrifugation.
8. An NMN-containing amino acid body wash according to claim 1, further comprising one or more of a preservative, a chelating agent, a pH adjuster, deionized water.
Preferably, the preservative is a compound of p-hydroxyacetophenone and 1, 2-hexanediol to replace the traditional preservative.
Preferably, the preservative comprises, by mass, 0.3-0.8% of p-hydroxyacetophenone and 0.3-1.5% of 1, 2-hexanediol.
Preferably, the chelating agent is disodium EDTA.
Preferably, the chelating agent is 0.1-0.5% of EDTA disodium by mass percent.
Preferably, the pH regulator is citric acid, sodium citrate, lactic acid, sodium lactate, arginine.
Preferably, the pH regulator is citric acid or sodium citrate.
9. A method of making an NMN-containing amino acid shower gel according to claims 1-3, comprising the steps of:
(1) putting deionized water, chelating agent, amino acid surfactant, amphoteric surfactant and nonionic surfactant into a stirring pot, heating to 80-85 ℃, and stirring for dissolving uniformly;
(2) heating p-hydroxyacetophenone and 1, 2-hexanediol in an auxiliary pot to dissolve the p-hydroxyacetophenone and the 1, 2-hexanediol to be transparent;
(3) cooling the stirred kettle to 60-65 ℃, slowly adding a transparent mixture of p-hydroxyacetophenone and 1, 2-hexanediol, and uniformly stirring and dissolving;
(4) cooling to 40-45 deg.C, adding NMN and Mel extract, stirring and dissolving;
(5) adding pH regulator to regulate pH of the paste (10% water solution) to 6-6.5;
(6) and (5) filtering and discharging.
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| CN202210555413.0A CN114748408A (en) | 2022-05-19 | 2022-05-19 | NMN-containing amino acid shower gel and preparation method thereof |
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| CN202210555413.0A CN114748408A (en) | 2022-05-19 | 2022-05-19 | NMN-containing amino acid shower gel and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109276494A (en) * | 2018-09-30 | 2019-01-29 | 江门职业技术学院 | A kind of inflammation-resisting itch-stopping shower cream and preparation method thereof |
| CN111225657A (en) * | 2017-10-16 | 2020-06-02 | 田中惠 | Cosmetic composition containing nicotinamide mononucleotide |
| CN111973522A (en) * | 2019-05-22 | 2020-11-24 | 思蓝(北京)科技有限公司 | Bubble shampoo and shower gel for children |
| CN112107533A (en) * | 2020-09-27 | 2020-12-22 | 广州妮趣化妆品有限公司 | Composition with effects of controlling oil, tendering skin and collecting fine pores and preparation method and application thereof |
-
2022
- 2022-05-19 CN CN202210555413.0A patent/CN114748408A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111225657A (en) * | 2017-10-16 | 2020-06-02 | 田中惠 | Cosmetic composition containing nicotinamide mononucleotide |
| CN109276494A (en) * | 2018-09-30 | 2019-01-29 | 江门职业技术学院 | A kind of inflammation-resisting itch-stopping shower cream and preparation method thereof |
| CN111973522A (en) * | 2019-05-22 | 2020-11-24 | 思蓝(北京)科技有限公司 | Bubble shampoo and shower gel for children |
| CN112107533A (en) * | 2020-09-27 | 2020-12-22 | 广州妮趣化妆品有限公司 | Composition with effects of controlling oil, tendering skin and collecting fine pores and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 上海虹久: "《人人都在刷酸，效果真的这么好吗》", 科学技术文献出版社, pages: 13 * |
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