CN113693976A

CN113693976A - Sericin stock solution shampoo and preparation method thereof

Info

Publication number: CN113693976A
Application number: CN202110969597.0A
Authority: CN
Inventors: 张启清; 余海励; 杨水波; 孙绪友
Original assignee: Shanghai Jieshibao Daily Chemical Group Co ltd
Current assignee: Shanghai Jieshibao Daily Chemical Group Co ltd
Priority date: 2021-08-23
Filing date: 2021-08-23
Publication date: 2021-11-26

Abstract

The invention relates to a sericin stock solution shampoo and a preparation method thereof, wherein the sericin stock solution shampoo comprises the following raw material components: rose fermentation liquor, traditional Chinese medicine extract, surfactant, fatting agent, cationic polymer, humectant, thickener, preservative, essence, pH regulator and the balance of sericin stock solution; the traditional Chinese medicine extract is a mixed extract of angelica root, cacumen biotae and sophora flavescens root; the solid content of the sericin powder in the sericin stock solution is not less than 0.30%. The invention has the beneficial effects that: according to the sericin stock solution shampoo, the sericin stock solution is used for replacing pure water to prepare the anhydrous formula shampoo for the first time, and the anhydrous formula shampoo is compounded with rose fermentation liquor, a traditional Chinese medicine extract and a humectant for use and is supplemented with a proper weight ratio, so that the components have a synergistic effect, the softness and toughness of hair can be enhanced, and meanwhile, the shampoo has excellent effects of removing dandruff and preserving moisture.

Description

Sericin stock solution shampoo and preparation method thereof

Technical Field

The invention belongs to the technical field of daily chemicals, and particularly relates to sericin stock solution shampoo and a preparation method thereof.

Background

Due to changes in environmental pollution, living habits, and the like, people have increased hair washing frequency. According to statistical data, the average hair washing frequency of global population is 3-5.6 times per week, the average hair washing frequency of national population is 3.31 times per week, and 11.59% of people need to wash hair every day. The increase of the hair washing frequency means that people are more frequently contacted with the hair washing product, and the people who are sensitive to the scalp are increased at present, so that the requirements of people on the hair washing product are increased, and on the basis of ensuring cleanness, safety and conditioning performance, the effects of improving the flexibility of the hair, preventing hair loss, repairing scalp barriers and the like are more expected.

On the other hand, consumers are more and more inclined to select the alleged products of 'no irritation', 'natural', and the like, and 'no silicone oil' is one of the popular selling points. However, the shampoo product without the silicone oil is poor in smoothness and feel, so that the shampoo feel is strong, and a natural silicone oil substitute is found to meet the market demand and has great application potential.

Disclosure of Invention

The invention aims to provide natural shampoo which can achieve or even exceed the smoothing effect brought by a traditional silicone oil formula system and has excellent multiple effects including hair strengthening, dandruff removing and scalp moisturizing.

In order to achieve the purpose, the invention adopts the following technical scheme:

the invention provides sericin stock solution shampoo which comprises the following raw material components in percentage by mass: 1-5% of rose fermentation liquor, 0.2-0.5% of traditional Chinese medicine extract, 25-50% of surfactant, 1-4% of fatting agent, 0.1-0.5% of cationic polymer, 0.1-2% of humectant, 1-4% of thickening agent, 0.1-1.2% of preservative, 0.1-1.5% of essence, 0.2-0.4% of pH regulator and the balance of sericin stock solution; the traditional Chinese medicine extract is a mixed extract of angelica root, cacumen biotae and sophora flavescens root; the solid content of the sericin powder in the sericin stock solution is not less than 0.30%. Preferably, the material comprises the following raw material components in percentage by mass: 1-2% of rose fermentation liquor, 0.2-0.3% of traditional Chinese medicine extract, 30-46% of surfactant, 1.4-2.8% of fatting agent, 0.2-0.3% of cationic polymer, 0.3-0.5% of humectant, 2-3.5% of thickening agent, 0.5-1.2% of preservative, 0.3-0.6% of essence, 0.2-0.3% of pH regulator and the balance of sericin stock solution.

Sericin is fibroin which is positioned on the periphery of cocoon silk and coated on the periphery of fibroin, the sericin is spherical protein and contains 18 amino acids, wherein the content of amino acids necessary for a human body reaches more than 18 percent, the molecular conformation of the easily soluble sericin is mainly a random coil structure, the aggregation structure of a high polymer of the sericin is mainly an amorphous structure, and the sericin is a natural moisturizing factor substance and can effectively prevent the skin from being dried, wrinkled and aged and inhibit the generation of melanin in the skin. Meanwhile, the skin care product has the functions of resisting oxidation, resisting the erosion of ultraviolet rays, sunlight, microwaves, chemical substances and atmospheric pollutants to the skin, reducing inflammatory reaction, promoting cell proliferation and the like. The degumming solution of silk is processed by procedures of decolorization, enzymolysis, ion exchange purification, concentration, spray drying and the like to obtain high-purity soluble sericin powder. The sericin powder has the excellent performances of good water solubility, fine and uniform granularity, good appearance color and luster and the like.

The sericin stock solution is used as a solvent instead of water, is combined with the angelica root extract, the cacumen biotae extract, the sophora flavescens root extract, the rose fermentation liquor and the polyglycerol-10 for use, and is added into shampoo, wherein sericin can form a protective transparent film on the surface of hair, so that the luster and the elasticity of the hair are improved, and meanwhile, the hair is repaired by permeating into the hair; the rose fermentation liquor contains abundant nutrient components such as flavone, polysaccharide, amino acid and the like, can promote the growth of beneficial bacteria on the scalp and inhibit the growth of harmful bacteria, and further has the function of regulating the microecology of the scalp; the radix Angelicae sinensis extract, folium Platycladi extract and radix Sophorae Flavescentis extract can dilate scalp capillary vessel and promote blood circulation, thereby enhancing hair follicle metabolism, removing dandruff, and promoting hair regeneration; polyglycerol-10 aids in enhancing moisturization. Tests prove that the shampoo prepared by compounding the components has better compounding and synergistic effects on the aspects of improving the flexibility of hair after washing, strengthening and toughening the hair and removing dandruff. The shampoo disclosed by the invention can reduce the percutaneous dehydration of the scalp, so that the scalp is repaired, and further, the excellent moisturizing and relieving effects are achieved.

The sericin stock solution and the traditional Chinese medicine extract adopted by the invention can be obtained from commercial sources, such as the biological science and technology limited company of Chinese silks and Guangdong Boxi, respectively. The rose fermentation liquor can also be obtained from a commercial channel, and is preferably prepared according to the preparation method of the rose fermentation liquor in the invention patent CN111789801A moisture-keeping shower gel containing the rose fermentation liquor and the preparation method thereof.

According to the sericin stock solution shampoo, the surfactant is selected from any one or more of sodium laureth sulfate, sodium C14-16 olefin sulfonate, disodium lauryl sulfosuccinate, disodium cocoyl glutamate, cocamidopropyl betaine, lauramidopropyl betaine, cocamidopropyl hydroxysultaine, sodium cocoamphoacetate, sodium lauroyl sarcosinate, sodium cocoyl alanine, alkyl glucoside and sodium methyl cocoyl taurate. Specifically, when the amino acid surfactant is used as the main surfactant, the surfactant is composed of disodium cocoyl glutamate, cocamidopropyl betaine, alkyl glucoside and sodium methyl cocoyl taurate according to the weight ratio of 15-30:10-25:1-5: 1-6. When the sulfate surfactant is used as the main surfactant, the surfactant is composed of sodium laureth sulfate, cocamidopropyl betaine, alkyl glucoside and sodium methyl cocoyl taurate according to the weight ratio of 12-20:1-5:3-10:1-5: 1-6.

According to the sericin stock solution shampoo, the fatting agent is selected from one or more of ethylene glycol distearate, glycerol laurate, propylene glycol laurate, isostearyl alcohol pivalate, PPG-3 octyl ether and cetostearyl alcohol. Preferably, the fat-imparting agent consists of ethylene glycol distearate, glycerol laurate, propylene glycol laurate, isostearyl alcohol pivalate and PPG-3 octyl ether in a weight ratio of 0.5-2:0.1-1:0.1-1:0.1-1: 0.1-1.

According to the sericin stock solution shampoo, the cationic polymer is guar gum hydroxypropyl trimethyl ammonium chloride, and the humectant is polyglycerol-10. The thickening agent is selected from any one or more of sodium chloride, cocamide MEA, PEG-120 methyl glucose dioleate, polyacrylic acid copolymer and polyacrylate copolymer, preferably cocamide MEA and polyacrylate copolymer; the preservative is selected from any one or more of cason, phenoxyethanol and sodium benzoate.

The preparation method of the sericin stock solution shampoo comprises the following steps: mixing surfactant, fat-imparting agent, and cationic polymer, heating to 60-80 deg.C for dissolving completely, cooling to below 45 deg.C, adding the rest materials, and stirring.

The invention has the beneficial effects that:

according to the sericin stock solution shampoo, the sericin stock solution is used for replacing pure water to prepare the anhydrous formula shampoo for the first time, and the anhydrous formula shampoo is compounded with rose fermentation liquor, a traditional Chinese medicine extract and a humectant for use and is supplemented with a proper weight ratio, so that the components have a synergistic effect, the softness and toughness of hair can be enhanced, and meanwhile, the shampoo has excellent effects of removing dandruff and preserving moisture.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.

In the following examples, the sericin stock solution was obtained from Chinese silks, the solid content of the sericin powder was 0.30%, and the hygiene indexes including the heavy metal content and the number of colonies all met the regulations of technical specifications for cosmetic safety (2015). The hydrolyzed fibroin 1 is purchased from Chinese silks, is light yellow liquid, has unique smell of fibroin, has the solid content of the hydrolyzed fibroin of 0.30 percent, and has the health indexes of heavy metal content and the number of colonies meeting the regulations of technical specifications for cosmetic safety (2015 edition). Hydrolyzed fibroin 2 is available from Japanese chemical synthesis, has a molecular weight of 1000, and is recommended to be used in an amount of 1.0-5.0%, and has a hydrolyzed protein content of 6.5%. The rose fermentation liquid was prepared according to the method of preparation of rose fermentation liquid of CN 111789801A-preparation example 1. The Chinese medicinal extract mainly comprises radix Angelicae sinensis extract, folium Platycladi extract, and radix Sophorae Flavescentis extract, and is available from Guangdong Boxi biotechnology limited.

TABLE 1 shampoo formulations

TABLE 2 shampoo formulations

Preparing the shampoo:

(1) accurately weighing each raw material for later use; cleaning a main stirring pot, starting stirring, adding disodium cocoyl glutamate, cocamidopropyl betaine, alkyl glucoside, sodium methyl cocoyl taurate, guar hydroxypropyl trimethyl ammonium chloride, ethylene glycol distearate, glycerol laurate, propylene glycol laurate, cocamidomethyl MEA, PPG-3 octyl ether, isostearyl pivalate and climbazole into the main stirring pot one by one, stirring uniformly, and starting heating to 80 ℃; stirring to dissolve completely, and stirring for 30 min;

(2) cooling, adding the rest materials into the main kettle when the temperature is reduced to 45 ℃, and stirring for 20min to be completely uniform;

(3) and (5) standing and sampling, and discharging after the semi-finished product sampling detection meets the standard.

TABLE 3 shampoo formulations

Preparing the shampoo:

(1) accurately weighing each raw material for later use; cleaning a main stirring pot, starting stirring, respectively adding sodium laureth sulfate, cocamidopropyl betaine, alkyl glucoside, sodium methyl cocoyl taurate, guar hydroxypropyl trimethyl ammonium chloride, ethylene glycol distearate, cetostearyl alcohol and cocamidomethyl MEA (methyl MEA) into the main stirring pot one by one, stirring uniformly, and starting heating to 75 ℃; stirring to dissolve completely, and stirring for 30 min;

(2) cooling, adding the rest materials into the main kettle when the temperature is reduced to 40 ℃, and stirring for 20min to be completely uniform;

First, smoothness and hair flexibility test

1. In vitro hair strand pretreatment

3g of one tress of hair was immersed in 200ml of isopropyl alcohol (IPA) for 10 minutes to keep the hair wax washed away; the tresses were soaked in 1.6% sodium laureth sulfate (SLES) warm solution (50 ℃) for 30 minutes and the tresses were rinsed with tap water to completely remove the washing solution. The tresses were rinsed with 1 ml of 16% SLES solution for 1 minute and then rinsed under running water for 30 seconds. This step was repeated 2 times. Dried overnight in a room at 25 ℃.

2. Smooth degree soaking test of fibroin aqueous solution

TABLE 4

Respectively preparing the solutions, stirring uniformly, respectively soaking 5 pretreated hair strands in the solutions for 20min, respectively washing the hair strands for one minute with running water, hanging the hair strands in a constant temperature and humidity chamber for 24h, and testing the smoothness and flexibility of each hair strand.

24 subjects participate in smoothness and flexibility evaluation, and the evaluation method is that each silk protein liquid and silicone oil form a group, and one of the silk protein liquids is selected to be smoother or softer and is marked as 1 point; otherwise, it is marked as 0. The results, which cannot be judged, were considered as being equally smooth or soft, and were all scored as 1 point, were as follows:

TABLE 5

It can be seen from this experiment that only the sericin stock solution (Chinese silk) in the aqueous solution had better smoothness and flexibility than silicone oil. Since deposition in aqueous solution may not be the same as deposition in formulation, we also performed smoothness and softness tests in shampoo formulations with addition of sericin stock or silicone oil. The results are shown in the following table.

TABLE 6

TABLE 7

Two experiments are carried out according to the formulas in the tables 6 and 7, 1g of the sample is respectively taken and smeared on the pretreated hair bundle (the hair bundle is numbered in advance), the hair bundle is slightly kneaded for 1 minute, washed for 1 minute by running water, the process is repeated for two times, the clean face paper is used for absorbing the moisture on the hair bundle, the hair bundle is placed in a constant temperature and humidity chamber to be kept still for 24 hours for drying, the hand feeling of a consumer is used for evaluating the smoothness and the flexibility of the two hair bundles, 24 subjects participate in the smoothness and the flexibility evaluation, the evaluation method is that the most smooth hair bundle is selected from the three hair bundles, the number is 2, the next number is 1, and the least smooth hair bundle is 0; the softest of the three tresses was chosen to be 2 points, the next 1 point, and the least soft was 0 points, with the following results:

TABLE 8

Smoothness score/number of people	Total score	Average score
			Example 6	33	1.375
Comparative example 4	15	0.625
			Comparative example 5	24	1
Degree of compliance	Total score	Average score
			Example 6	34	1.417
Comparative example 4	27	1.125
			Comparative example 5	11	0.458

TABLE 9

Degree of compliance	Total score	Average score
			Comparative example 7	29	1.208333
Comparative example 8	27	1.125
			Comparative example 9	16	0.666667
Degree of smoothness	Total score	Average score
			Comparative example 7	29	1.208333
Comparative example 8	19	0.791667
			Comparative example 9	24	1

Example 6, comparative example 4 and comparative example 5 show that the sericin stock solution (Chinese silk) with the same concentration has higher smoothness and softness than hydrolyzed fibroin (Chinese silk) and hydrolyzed fibroin (remu); comparative examples 7 to 9 it can be seen that the sericin stock solution (Chinese silk) is more smooth and flexible than the large-particle size silicone oil emulsion and the small-particle size silicone oil emulsion, and thus has potential as an active substance for smoothing and softening hair instead of silicone oil.

Second, efficacy test of strong hair

Whether the shampoo has the effects of preventing broken hair and strengthening and toughening hair by repairing hair is tested according to the T/GDCDC 012 and 2020 hair product strengthening and toughening effect evaluation method.

And selecting qualified in-vitro human hairs, namely one group of the ex-vivo human hairs in example 6, comparative examples 1 to 5 and comparative examples 8 to 9, wherein the effective amount of each group is more than 30. Washing the isolated hair bundle to be tested with flowing constant-temperature clear water, uniformly using the isolated hair bundle on the surface of the hair according to the use of 0.2 g of sample per gram of hair bundle, using for 20-30 seconds per month, then washing and printing dry moisture by using a clean paper towel, placing the isolated hair bundle in a constant-temperature and constant-humidity [ (26[2 ] DEG C and (60[ 10)% RH ] environment for naturally airing for 24 hours, and carrying out single-root tensile test on an MTT175 tensile test instrument.

Tensile strength Mpa-tensile force (load) N/cross-sectional area (diameter) μm;

wherein the tensile force (load) N, the force in tension, is directly obtained by an MTT175 tensile test instrument;

the sectional area (diameter) μm, the hair diameter, is obtained by a hair measuring instrument.

Tensile strength-tensile strength after use of the product-tensile strength before use of the product;

the experimental results gave the following tensile strengths:

watch 10

Example 6	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4	Comparative example 5	Comparative example 8	Comparative example 9
								0.46	0.23	0.32	0.4	0.31	0.33	0.33	0.37

The experimental data show that the addition of fibroin or silicone oil is beneficial to the toughness of the hair; the higher the concentration of the added fibroin is, the more the toughness of the hair is increased; the comparison of example 6, comparative example 4 and comparative example 5 shows that the addition of sericin stock solution (Chinese silk) with the same concentration has stronger hair strength and tenacity than hydrolyzed fibroin (Chinese silk) and hydrolyzed fibroin (remu); the comparison of example 6, comparative example 8 and comparative example 9 shows that the silk fibroin raw liquid (Chinese silk) with the concentration of the invention has stronger strength and toughness than the traditional silicone oil formula system of a large-particle-size silicone oil emulsion and a small-particle-size silicone oil emulsion.

Third, shampoo dandruff removing capability test

The testing personnel: 55 volunteers with significant dandruff were recruited as subjects, 27 men and 28 women, and all subjects had excessive dandruff such as flaky white scales on their heads. All shampoo, hair care and daily chemical products with the anti-dandruff effect are stopped for the first two weeks.

The using method comprises the following steps: the subjects were divided into 11 groups, and the subjects used the shampoos of examples 1-6 and comparative examples 6-8, example 9, and comparative example 11, respectively, and the subjects used the shampoos of the corresponding group at least 3 times per week, and evaluated by a professional qualified dermatologist.

The clinical evaluation method comprises the following steps: clinical evaluation was performed using ASFS score (adhesive scalp scraping score) with no visible desquamation of 0 score; the occasional tiny desquamation of hair roots is 1 minute; a small amount of large desquamation or a large amount of fine desquamation is 3 minutes; the large amount of desquamation is 4 minutes. The scoring was done before shampooing, on days 0, 14, and 28 at the start of the experiment. The 28 th balance minus day 0 score is in the table.

TABLE 11

The test result of the anti-dandruff capability of the shampoo shows that in example 6, the ratio of the fibroin to the rose fermentation liquor to the traditional Chinese medicine extract is 43.6:1:0.2, the anti-dandruff effect is the best, and the anti-dandruff effect is better than that of the conventional anti-dandruff agent climbazole.

Fourth, scalp percutaneous dehydration effect test

55 volunteers aged 18-60 years were selected and randomly divided into 11 groups of 5 individuals each. Using each of the examples and comparative examples, subjects used shampoo of the corresponding group at least 3 times per week.

The shampoo using method comprises the following steps: fully moistening the whole scalp, rubbing 5-10 mL of shampoo to remove foams, and then applying the foams on scalp hairlines. The finger abdomen is kneaded for 3-5 minutes and then cleaned with clear water.

Selecting the center of the vertex of the head as a test part, testing the moisture content of the stratum corneum of the scalp by using a moisture tester probe Corneometer CM825 of a skin moisture tester on the 0 th day, the 14 th day and the 28 th day of the experiment, and averaging the test times; scalp percutaneous water loss was measured on days 0, 14, and 28 of the experiment using a very small skin water loss TEWL test probe, Tewameter (TM) Nano, and the average value was taken over three times, and the change of the TEWL value from day 28 minus day 0 is shown in the table.

TABLE 12

It can be seen that in example 6, the ratio of the fibroin to the rose fermentation liquor to the traditional Chinese medicine extract is 43.6:1:0.2, the effect on improving the scalp percutaneous water loss is the best, and the compound synergistic effect is achieved.

The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims

1. The sericin stock solution shampoo is characterized by comprising the following raw material components in percentage by mass:

1-5% of rose fermentation liquor, 0.2-0.5% of traditional Chinese medicine extract, 25-50% of surfactant, 1-4% of fatting agent, 0.1-0.5% of cationic polymer, 0.1-2% of humectant, 1-4% of thickening agent, 0.1-1.2% of preservative, 0.1-1.5% of essence, 0.2-0.4% of pH regulator and the balance of sericin stock solution;

the traditional Chinese medicine extract is a mixed extract of angelica root, cacumen biotae and sophora flavescens root;

the solid content of the sericin powder in the sericin stock solution is not less than 0.30%.

2. The sericin stock solution shampoo as defined in claim 1, which comprises the following raw material components in percentage by mass:

1-2% of rose fermentation liquor, 0.2-0.3% of traditional Chinese medicine extract, 30-46% of surfactant, 1.4-2.8% of fatting agent, 0.2-0.3% of cationic polymer, 0.3-0.5% of humectant, 2-3.5% of thickening agent, 0.5-1.2% of preservative, 0.3-0.6% of essence, 0.2-0.3% of pH regulator and the balance of sericin stock solution.

3. The sericin stock shampoo as defined in claim 1, wherein the surfactant is selected from one or more of sodium laureth sulfate, sodium C14-16 olefin sulfonate, disodium lauryl sulfosuccinate, disodium cocoyl glutamate, cocamidopropyl betaine, lauramidopropyl betaine, cocamidopropyl hydroxysultaine, sodium cocoamphoacetate, sodium lauroyl sarcosinate, sodium cocoyl alanine, alkyl glucoside, and sodium methylcocoyl taurate.

4. The sericin stock shampoo as defined in claim 3, wherein the surfactant is composed of disodium cocoyl glutamate, cocamidopropyl betaine, alkyl glucoside, and sodium methylcocoyl taurate in a weight ratio of 15-30:10-25:1-5: 1-6.

5. The sericin stock shampoo as defined in claim 3, wherein the surfactant is composed of sodium laureth sulfate, cocamidopropyl betaine, alkyl glucoside, and sodium methylcocoyltaurate in a weight ratio of 12-20:1-5:3-10:1-5: 1-6.

6. The sericin stock solution shampoo as defined in claim 1, wherein the lipid-imparting agent is one or more selected from the group consisting of ethylene glycol distearate, glycerol laurate, propylene glycol laurate, isostearyl pivalate, PPG-3 octyl ether, and cetearyl alcohol.

7. The sericin stock solution shampoo as defined in claim 6, wherein the fat-imparting agent comprises ethylene glycol distearate, glycerol laurate, propylene glycol laurate, isostearyl pivalate and PPG-3 octyl ether in a weight ratio of 0.5-2:0.1-1:0.1-1:0.1-1: 0.1-1.

8. The sericin stock shampoo as defined in claim 1, wherein the cationic polymer is guar hydroxypropyl trimonium chloride, and the humectant is polyglycerol-10.

9. The sericin stock shampoo as defined in claim 1, wherein the thickener is selected from any one or more of sodium chloride, cocamide MEA, PEG-120 methyl glucose dioleate, polyacrylic acid copolymer and polyacrylate copolymer; the preservative is selected from any one or more of cason, phenoxyethanol and sodium benzoate.

10. The method for preparing the sericin stock shampoo as defined in any one of claims 1 to 9, which comprises the following steps: mixing surfactant, fat-imparting agent, and cationic polymer, heating to 60-80 deg.C for dissolving completely, cooling to below 45 deg.C, adding the rest materials, and stirring.