CN112107533A

CN112107533A - Composition with effects of controlling oil, tendering skin and collecting fine pores and preparation method and application thereof

Info

Publication number: CN112107533A
Application number: CN202011031342.1A
Authority: CN
Inventors: 张青; 李洪海; 汤仲标; 向琴
Original assignee: Tianjin Niqu Biotechnology Co ltd; Guangzhou Niqu Cosmetics Co ltd
Current assignee: Tianjin Niqu Biotechnology Co ltd; Guangzhou Niqu Cosmetics Co ltd
Priority date: 2020-09-27
Filing date: 2020-09-27
Publication date: 2020-12-22
Anticipated expiration: 2040-09-27
Also published as: CN112107533B

Abstract

The invention belongs to the field of cosmetics, and relates to a composition with effects of controlling oil, tendering skin and reducing fine pores, and a preparation method and application thereof. The composition comprises honey extract, fig extract, olive leaf extract. The composition formed by matching the honey extract, the fig extract and the olive leaf extract has the synergistic effect of all the components, so that the water and oil of the skin are effectively balanced, the cutin is gently peeled off, and the skin is smooth and fine. Meanwhile, the composition can enhance the skin barrier, promote the absorption of active substances, repair sensitive muscles and enable the skin to be moist and bright after long-term use.

Description

Composition with effects of controlling oil, tendering skin and collecting fine pores and preparation method and application thereof

Technical Field

The invention belongs to the technical field of skin care products, and particularly relates to a composition with effects of controlling oil, tendering skin and collecting fine pores, and a preparation method and application thereof.

Background

With the increasing age, the over-pressure of society, the environmental pollution, the computer radiation and other problems becoming more serious, a lot of adverse effects are caused to the skin, and more people are mixed with oily skin. At present, many young people have a series of skin problems such as full gloss, large pores, dark yellow skin, rough and loose skin and the like, and the skin problems bring different troubles to social activities.

At present, in the existing cosmetics, in order to control or regulate sebum secretion and refine pores, a plurality of oil-absorbing powder components or acid brushing are mainly adopted. Oil-absorbing powders such as silica, nylon powder, zinc oxide, boron nitride, polymethyl methacrylate, silicon elastomer, etc. hardly have further effects in addition to the effect of absorbing sebum, and these powder components can rapidly fill pores, but cannot fundamentally change the fact that the pores are large. Brushing acids, such as salicylic acid, neoylsalicylic acid, glycolic acid, lactobionic acid, gluconolactone, mandelic acid, and the like, remove old and waste cutin by disrupting reconstructed skin stratum corneum, and dredge pores, but have large side effects, easily cause skin sensitivity, and bring other skin problems. In addition, the method for reducing sebum secretion and shrinking pores by adopting medicinal components, for example, the method for inhibiting excessive secretion of in vivo androgen to achieve the effect of controlling oil is adopted, but the medicament has great side effect and is not easy to take for a long time.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides a composition with the effects of controlling oil, tendering skin and reducing fine pores, and a preparation method and application thereof. The composition is a natural fermentation source, is mild and non-irritant, has better effects of controlling oil, tendering skin and shrinking pores, can enhance skin barrier, promotes absorption of active substances, repairs sensitive muscles, and can make skin moist and bright after long-term use. Can be used as a functional additive of a skin care product for controlling oil, tendering skin and shrinking pores, and has wide application prospect.

In one aspect, the invention provides a composition comprising honey extract, fig extract, olive leaf extract.

Honey EXTRACT, INCI name HONEY EXTRACT.

Ficus CARICA EXTRACT, INCI is FICUS CARICA (FIG) EXTRACT.

OLIVE LEAF EXTRACT, INCI under the name OLEA EUROPAEA (OLIVE) LEAF EXTRACT.

Honey, which is sweet and mild in nature; shen nong Ben Cao Jing: "governing heart and abdomen pathogenic qi, fright epilepsy and convulsion, calming the five internal organs and insufficiency, tonifying qi and strengthening the middle-jiao, relieving pain and removing toxicity, removing diseases, mixing with various medicines, strengthening will and reducing weight after long-term administration, not hunger and not old", and has the two functions of treating diseases and strengthening body; modern pharmacological research proves that the external honey has a plurality of functions of detoxifying, resisting bacteria, diminishing inflammation, moistening, preventing corrosion, curing sore, relieving pain, protecting and repairing wound surfaces, promoting cell regeneration and the like. The Mel extract is prepared by selecting flos Rosae Rugosae Mel, fermenting with Gluconobacter at 15-40 deg.C and pH of 3.0-8.0, extracting the Mel after fermentation with 1, 3-butanediol, filtering, and centrifuging. The honey extract after fermentation treatment contains high-concentration gluconic acid, and has the effects of mildly brightening the skin and brightening the skin.

Fig, which is sweet in taste and neutral in nature, contains polyphenols, vitamins B1, B2, C, as one of the oldest edible fruits in the world, and is called a non-aged pecan having a cosmetic effect. Fructus fici extract is prepared by fermenting fructus fici with yeast in Mel at 15-40 deg.C and pH of 3.0-8.0, extracting the fermented fructus fici with 1, 3-butanediol, filtering, and centrifuging. The fermented fig extract has excellent moisturizing performance, and can promote the formation of hyaluronic acid, balance skin water and oil, and endow skin with elasticity.

Olive leaves, the first mentioned plant in the bible, fruits can be used as food and leaves can be used as medicine. The most active substance in olive leaves is oleuropein, which has excellent antioxidant effect and can repair and promote collagen. The olive leaf extract is prepared by fermenting with bacteria belonging to genus Zymomyces at 15-40 deg.C and pH of 3.0-8.0, sterilizing by heating at high temperature for 20-30 min, extracting with 1, 3-butanediol, filtering, and centrifuging. The olive leaf extract subjected to fermentation treatment can effectively improve the oleuropein content, inhibit sebum secretion, inhibit sebum oxidation, promote collagen production and repair fine pores.

In some embodiments, the composition comprises a combination of the following parts by weight: 30-70 parts of honey extract, 10-30 parts of fig extract and 20-50 parts of olive leaf extract.

In some embodiments, the weight parts of the honey extract may be 30 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts.

In some embodiments, the parts by weight of the fig extract may be 10 parts, 12 parts, 15 parts, 17 parts, 20 parts, 22 parts, 25 parts, 27 parts, 30 parts.

In some embodiments, the parts by weight of the olive leaf extract may be 20 parts, 25 parts, 30 parts, 35 parts, 37 parts, 40 parts, 42 parts, 45 parts, 47 parts, 50 parts.

In some embodiments, the honey extract is 35-65 parts, the fig extract is 15-27 parts, and the olive leaf extract is 25-47 parts.

In some embodiments, the honey extract is 40-65 parts, the fig extract is 15-25 parts, and the olive leaf extract is 25-45 parts.

In some embodiments, the honey extract is 45-60 parts, the fig extract is 15-22 parts, and the olive leaf extract is 30-40 parts.

In another aspect, the present invention provides a method of preparing the composition, comprising the steps of: respectively weighing Mel extract, fructus fici extract, and Olea europaea leaf extract, mixing, stirring at constant temperature, and filtering.

In some embodiments, the constant temperature is 25-40 deg.C, such as 25 deg.C, 27 deg.C, 30 deg.C, 33 deg.C, 35 deg.C, 37 deg.C, 40 deg.C, preferably 35 deg.C.

In some embodiments, the stirring speed is 200-400rpm, such as 200rpm, 250rpm, 300rpm, 350rpm, 400rpm, and preferably 300 rpm.

In some embodiments, the filtration pore size is 200-600 mesh; for example, the mesh size may be 200 mesh, 300 mesh, 400 mesh, 500 mesh, 600 mesh, preferably 500 mesh.

In another aspect, the present invention provides the use of said composition in cosmetics.

In the present invention, the cosmetic is selected from a cream, an emulsion, an essence, a lotion, a gel or a mask, and is not particularly limited.

In some embodiments, the cosmetic is selected from a lotion, essence, or mask.

In some embodiments, the cosmetic is an oil control skin rejuvenation and pore reducing product.

In another aspect, the present invention provides a cosmetic comprising the composition.

In some embodiments, in the cosmetic, the composition is present in an amount of 1-20% by weight;

more preferably, the weight percentage of the composition is 5-17%; even more preferably, the weight percentage of the composition is 8-15%.

In some embodiments, the cosmetic further comprises one or more of allantoin, panthenol, glycerin, sodium hyaluronate, xanthan gum, and water.

In one aspect, the present invention also provides a method of preparing the cosmetic, comprising the steps of:

(1) adding water, allantoin, glycerol, xanthan gum and sodium hyaluronate into a reaction kettle, heating to 80-85 deg.C, stirring, and homogenizing to completely dissolve;

(2) keeping the temperature for 5-10min, cooling to below 40 deg.C, adding panthenol and the composition, stirring, and homogenizing.

The composition formed by matching the honey extract, the fig extract and the olive leaf extract has the synergistic effect of all the components, so that the water and oil of the skin are effectively balanced, the cutin is gently peeled off, and the skin is smooth and fine.

Drawings

FIG. 1 is a graph showing a comparison of sebum secretion rates in test example 2;

FIG. 2 is a graph showing the comparison of the pore diameter reduction ratios of the pores in test example 2;

fig. 3 is a comparison graph of skin smoothness in test example 3.

Detailed Description

The technical solutions of the present application are further illustrated by the following specific examples, which do not represent a limitation to the scope of the present application. Insubstantial modifications and adaptations of the concepts taught herein by others are intended to be covered by the present disclosure.

The term "comprising" or "comprises" as used herein is intended to mean that the compositions (e.g., media) and methods include the recited elements, but not exclude other elements.

The honey extract, fig extract and olive leaf extract used in the examples of the present application were purchased from japan kennel company.

Example 1

The composition with the effects of controlling oil, tendering skin and reducing fine pores comprises the following components in parts by weight:

35 parts of honey extract, 30 parts of fig extract and 35 parts of olive leaf extract.

The preparation method comprises the following steps:

weighing the honey extract, the fig extract and the olive leaf extract according to the proportion, controlling the temperature at 30 ℃, controlling the stirring speed at 250rpm, uniformly stirring, and filtering by a 500-mesh sieve.

Example 2

45 parts of honey extract, 25 parts of fig extract and 30 parts of olive leaf extract.

The preparation method comprises the following steps:

weighing the honey extract, the fig extract and the olive leaf extract according to the proportion, controlling the temperature at 35 ℃, controlling the stirring speed at 300rpm, uniformly stirring, and filtering by a 500-mesh sieve.

Example 3

55 parts of honey extract, 15 parts of fig extract and 30 parts of olive leaf extract.

The preparation method comprises the following steps:

weighing the honey extract, the fig extract and the olive leaf extract according to the proportion, controlling the temperature at 35 ℃, controlling the stirring speed at 350rpm, uniformly stirring, and filtering by a 500-mesh sieve.

Comparative example 1

The conditions were the same as in example 1 except that 20 parts of honey extract, 60 parts of fig extract and 10 parts of olive leaf extract were used as compared with example 1.

Comparative example 2

The conditions were the same as in example 1 except that the honey extract was 75 parts, the fig extract was 8 parts, and the olive leaf extract was 17 parts, as compared with example 1.

Comparative example 3

Compared to example 1, the conditions were the same as example 1 except that only honey extract was added.

Comparative example 4

The conditions were the same as in example 1 except that only fig extract was added as compared with example 1.

Comparative example 5

The conditions were the same as in example 1 except that only olive leaf extract was added as compared with example 1.

Comparative example 6

The procedure of example 1 was repeated except that 70 parts of honey extract and 30 parts of fig extract were added, as compared with example 1.

Comparative example 7

The procedure of example 1 was repeated except that 70 parts of honey extract and 30 parts of olive leaf extract were added, as compared with example 1.

Comparative example 8

The conditions were the same as in example 1 except that only 70 parts of fig extract and 30 parts of olive leaf extract were added as compared with example 1.

Comparative example 9

Compared with example 1, the conditions were the same as example 1 except that honey extract without fermentation process was used instead of the honey extract in example 1.

Comparative example 10

Compared with example 1, the conditions were the same as example 1 except that fig extract of the fermentation process was used instead of fig extract of example 1.

Comparative example 11

The conditions were the same as in example 1 except that the olive leaf extract was substituted for the olive leaf extract in example 1, as compared with example 1.

Comparative example 12

Aqueous products are commercially available which claim to have oil control, skin rejuvenation and pore narrowing, the products containing glycolic acid.

Comparative example 13

The same conditions as in example 1 were used except that rosemary extract was used instead of olive leaf extract in example 1, as compared with example 1.

Test example 1 erythrocyte hemolysis test

PBC (erythrocyte hemolysis) is one of the alternatives of rabbit eye irritation experiments, and the basic principle is to evaluate the damage of chemicals to eye tissue cells by measuring the dissolution amount and denaturation degree of hemoglobin. The erythrocyte hemolysis test is mainly used for evaluating eye irritation research of chemicals such as cosmetics and raw materials internationally. This experiment was conducted according to the test method of PBC test by the European Alternatives validation center (ECVAM) and the classification criteria, which are shown in Table 1.

TABLE 1ECVAM grading Standard

Wherein L/D is the ratio of HD50 to DI, HD50 is the sample concentration at which 50% of erythrocytes are hemolyzed, and DI is the protein denaturation index.

The samples of examples 1 to 3 and comparative examples 1 to 12 were subjected to the erythrocyte hemolysis test, and the results thereof are shown in Table 2.

TABLE 2 test results of erythrocyte hemolysis experiment

Sample name	L/D	Grading
			Example 1	483.25	Has no irritation
Example 2	426.27	Has no irritation
			Example 3	365.85	Has no irritation
Comparative example 1	342.74	Has no irritation
			Comparative example 2	76.69	Micro-stimulation property
Comparative example 3	9.28	Mild irritation
			Comparative example 4	381.73	Has no irritation
Comparative example 5	88.94	Micro-stimulation property
			Comparative example 6	247.37	Has no irritation
Comparative example 7	321.46	Has no irritation
			Comparative example 8	462.71	Has no irritation
Comparative example 9	347.42	Has no irritation
			Comparative example 10	276.74	Has no irritation
Comparative example 11	90.58	Micro-stimulation property
			Comparative example 12	87.41	Micro-stimulation property

The results of erythrocyte hemolysis experiments show that the compositions with the effects of controlling oil and tendering skin and collecting fine pores in the embodiments 1-3 are classified into non-irritants, which indicates that the compositions with the effects of controlling oil and tendering skin and collecting fine pores provided by the invention are mild and non-irritants; the compositions of comparative examples 2 and 5 are classified as micro-irritation, and the composition of comparative example 3 is classified as mild irritation, which shows that the irritation can be obviously reduced by supplementing the substances; the composition of comparative example 11 was graded as microstimulation, indicating that the extract was milder through the fermentation process relative to the extract without the fermentation process. Comparative example 12 is classified as micro-irritant, indicating that a commercial glycolic acid-containing product alleged to have the efficacy of oil control, skin rejuvenation and pore narrowing, is somewhat irritant.

Example 4

A toner was prepared using the composition of example 2 having effects of controlling oil and tendering skin and reducing fine pores, and the specific formulation is shown in Table 3.

TABLE 3 formula table of toner for controlling oil and tendering skin and reducing fine pores

The preparation method of the toner comprises the following steps:

(1) putting the phase A into an emulsifying pot, heating to 80-85 ℃, and stirring and homogenizing until the phase A is uniformly dissolved;

(2) heating phase B to 60-70 deg.C, stirring to dissolve to transparent, slowly adding into emulsifying pot, and stirring;

(3) keeping the temperature for 5-10min, cooling to below 40 deg.C, adding C phase material, stirring and homogenizing to obtain paste;

(4) discharging after the detection is qualified.

Comparative example 14

The conditions were the same as in example 4 except that the composition of example 2 in example 4 was replaced with the composition of comparative example 1.

Comparative example 15

The conditions were the same as in example 4 except that the composition of example 2 in example 4 was replaced with the composition of comparative example 4.

Comparative example 16

The conditions were the same as in example 4 except that the composition of example 2 in example 4 was replaced with the composition of comparative example 7.

Comparative example 17

The conditions were the same as in example 4 except that the composition of example 2 in example 4 was replaced with the composition of comparative example 10.

Comparative example 18

The conditions were otherwise the same as in example 4, except that the composition of example 2 was not added.

Test example 2 sebum secretion Rate and skin capillary pore measurements

1. The test substance: inventive example 4, comparative examples 14-18.

2. Subject: 300 college students with an average age of 24 years, all had oily and mixed skin, had no history of skin disease and cosmetic allergy, and were randomly divided into 8 groups of 50 each, of which 20 men and 30 women were present.

3. The test method comprises the following steps: the subject was used after washing his face with morning and evening water. The forehead skin sebum secretion degree of the test subjects was analyzed using a skin analyzer model API100 manufactured by Aram HUVIS of korea continuously for 2 weeks (sebum secretion rate measurement), and the initial sebum secretion rate was defined as 100%, and the test results were arithmetic mean values of the sebum secretion rates of each group of the test subjects, and are shown in fig. 1.

Continuously using for 4 weeks, taking images of the pores in the same test position (cheek) before and after use by DIGIMIC800 type skin image analyzer, taking 3 images each time, analyzing the images to obtain the pore size, taking the arithmetic mean value, calculating the pore size reduction rate, and obtaining the calculation result shown in figure 2.

Pore size reduction rate (pore size before use-pore size after use)/pore size before use × 100%.

As can be seen from FIG. 2, the toner of the composition having the effects of controlling oil and rejuvenating skin and reducing fine pores prepared in example 4 and comparative examples 14 to 18 both had the effect of inhibiting sebum secretion, but the sebum secretion rate of the subject who tried the toner of the composition having the effects of controlling oil and rejuvenating skin and reducing fine pores prepared in example 4 was significantly lower than that of the subject who tried comparative examples 14 to 18, and particularly in the second week of trial, the sebum secretion rate of the subject of example 4 was reduced by about 50% from the initial stage. Compared with comparative examples 14-18, the single component or the component lacking any component or not in the proportion range or the component without the fermentation process has higher sebum secretion rate than that of example 4, which shows that the components of the composition with the effects of controlling oil and tendering skin and reducing fine pores have scientific and reasonable proportion, play a role in synergy and can effectively inhibit sebum secretion.

As can be seen from FIG. 3, the toner of the composition having effects of controlling oil and rejuvenating skin and reducing fine pores prepared in example 4 and comparative examples 14 to 18 both had inhibitory effects on reducing fine pores, but the shrinkage of the pore size in the subjects using the toner of the composition having effects of controlling oil and rejuvenating skin and reducing fine pores prepared in example 4 was significantly higher than that in the subjects using comparative examples 14 to 18, and the pore size in the subjects of example 4 was reduced by approximately 60% compared to the initial stage. Compared with comparative examples 14-18, the pore size shrinkage of the single component or the composition without any component or proportion range or the component without fermentation process is lower than that of example 4, which further shows that the composition with the effects of controlling oil, tendering skin and shrinking pores has scientific and reasonable proportion of the components, plays a role in synergy, not only effectively inhibits sebum secretion, but also can obviously shrink the pores.

Example 5

The composition with the effects of controlling oil, tendering skin and reducing pores in example 2 is used for preparing essence, and the specific formula is shown in table 4. formula table of essence with the effects of controlling oil, tendering skin and reducing pores in table 4

The preparation method of the essence comprises the following steps:

(1) putting the phase B into an emulsifying pot, heating to 80-85 ℃, and stirring and homogenizing until the phase B is uniformly dissolved;

(2) adding phase A into emulsifying pot, emulsifying, homogenizing and stirring for about 10min, and keeping the temperature for 5-10 min;

(3) heating the phase C to 60-70 ℃, stirring and dissolving until the phase C is transparent, and slowly putting the phase C into an emulsifying pot and uniformly stirring;

(4) cooling to below 40 ℃, adding the C-phase material, stirring and homogenizing until the paste is uniform;

(5) discharging after the detection is qualified.

Comparative example 19

The conditions were otherwise the same as in example 5, except that the composition of example 2 was not added.

Comparative example 20

The conditions were the same as in example 5 except that the composition of example 2 in example 5 was replaced with the composition of comparative example 13.

Test example 3 skin smoothness test

1. The test substance: inventive example 5, comparative example 19, comparative example 20.

2. Subject: 90 college students with an average age of 24 years in the school were all oily and mixed skin, had no skin disease and no history of cosmetic allergy, and were randomly divided into 3 groups of 5 males and 25 females per group.

3. The test method comprises the following steps: applying a proper amount of test substances on the face after cleaning the face in the morning and evening, continuously using for 2 weeks without using products with the effects of controlling oil and tendering skin and collecting fine pores during the test period, testing by adopting a VISIA facial image analyzer, recording smoothness data, taking an arithmetic average value, wherein the higher the data value is, the worse the skin smoothness is, and the test result is shown in figure 3.

As can be seen from the comparison graph of skin smoothness, compared with the comparison ratio of 19, the essence with the effects of controlling oil and tendering skin and shrinking pores prepared in example 5 can effectively improve the smoothness of the skin, and after 2 weeks of continuous use, the smoothness of the skin of a test subject in example 5 is improved by more than 60% compared with that before use, which shows that the composition with the effects of controlling oil and tendering skin and shrinking pores provided by the invention can effectively improve the smoothness of the skin and has a better skin tendering effect when being applied to a skin care product. Compared with the comparative ratio 20, the essence with the functions of controlling oil and tendering skin and shrinking pores prepared in the example 5 has obvious advantages in skin smoothness, and the composition with the functions of controlling oil and tendering skin and shrinking pores provided by the invention is an optimal combination, wherein any component cannot be replaced by other components.

In conclusion, the composition with the effects of controlling oil and tendering skin and collecting fine pores disclosed by the invention has the beneficial effects that the components are synergistic only under the condition of the mixture ratio of the components, so that the water and oil of the skin are effectively balanced, the cutin is gently peeled off, and the skin is smooth and fine. Meanwhile, the composition can enhance the skin barrier, promote the absorption of active substances, repair sensitive muscles and enable the skin to be moist and bright after long-term use.

In view of the many possible embodiments to which the principles of the disclosed invention may be applied, it should be recognized that the illustrated embodiments are only preferred examples of the application and should not be taken as limiting the scope of the application. Rather, the scope of the application is defined by the appended claims. We therefore claim as our invention all that comes within the scope and spirit of these claims.

Claims

1. A composition comprises honey extract, fig extract, olive leaf extract.

2. The composition of claim 1, comprising the following components in parts by weight: 30-70 parts of honey extract, 10-30 parts of fig extract and 20-50 parts of olive leaf extract.

3. The composition of claim 1, comprising the following components in parts by weight: 35-65 parts of honey extract, 15-27 parts of fig extract and 25-47 parts of olive leaf extract.

4. The composition of claim 1, comprising the following components in parts by weight: 40-65 parts of honey extract, 15-25 parts of fig extract and 25-45 parts of olive leaf extract.

5. The composition of claim 1, comprising the following components in parts by weight: 45-60 parts of honey extract, 15-22 parts of fig extract and 30-40 parts of olive leaf extract.

6. A process for preparing a composition according to any one of claims 2 to 5, comprising the steps of: respectively weighing Mel extract, fructus fici extract, and Olea europaea leaf extract, mixing, stirring at constant temperature, and filtering;

preferably, the constant temperature is 25-40 ℃;

preferably, the constant temperature is 25-35 ℃;

preferably, the stirring speed is 200-400 rpm;

preferably, the filtration pore size is 200-600 mesh.

7. Use of a composition according to any one of claims 1 to 5 in a cosmetic variety;

preferably, the cosmetic is selected from a cream, lotion, essence, aqua, gel or mask;

preferably, the cosmetic is selected from a lotion, essence or mask;

preferably, the cosmetic is an oil control skin rejuvenation and pore reducing product.

8. A cosmetic comprising the composition of any one of claims 1 to 5;

preferably, the weight percentage of the composition is 1-20%;

preferably, the weight percentage of the composition is 5-17%;

preferably, the weight percentage of the composition is 8-15%.

9. The cosmetic of claim 8, further comprising one or more of allantoin, panthenol, glycerin, sodium hyaluronate, xanthan gum, and water.

10. A method of preparing the cosmetic of claim 9, comprising the steps of:

(2) maintaining the temperature for 5-10min, cooling to below 40 deg.C, adding panthenol and the composition of any one of claims 1-5, stirring and homogenizing.