CN114712283A - Oil-control acne-clearing composition and application thereof in skin care products - Google Patents
Oil-control acne-clearing composition and application thereof in skin care products Download PDFInfo
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- CN114712283A CN114712283A CN202210380976.0A CN202210380976A CN114712283A CN 114712283 A CN114712283 A CN 114712283A CN 202210380976 A CN202210380976 A CN 202210380976A CN 114712283 A CN114712283 A CN 114712283A
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- Prior art keywords
- oil
- acne
- clearing
- controlling
- composition
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Abstract
The invention discloses an oil-control acne-clearing composition and application thereof in skin care products. The oil-controlling and acne-clearing composition comprises tetrahydromethylpyrimidine carboxylic acid, polylysine, white willow bark extract and yeast/zinc fermentation product; the weight ratio of the tetrahydromethylpyrimidine carboxylic acid to the polylysine to the white willow bark extract to the yeast/zinc fermentation product is (0.01-5): (0.00001-0.1): (0.01-3): (0.1-10). The composition for controlling oil and clearing pox aims at resisting inflammation, regulating skin microecology, regulating sebum secretion and promoting metabolism, and the four components have synergistic effect to improve the skin state of the oil pox muscle in multiple dimensions. The oil-control acne-clearing composition is applied to skin care products and has a good effect of improving the acne muscle.
Description
Technical Field
The invention relates to the technical field of beauty and skin care, in particular to an oil-control and acne-removing composition and application thereof in skin care products.
Background
Varicella muscle is a common problem skin condition. The expression form is that facial grease is exuberant in secretion, and the face is always full of oil and easy to remove makeup; excessive greasy deposits cause pore blockage in pores, and dirt which cannot be removed in time causes pox, even infection occurs to cause acne.
Skin care products aiming at the varicella muscles are on the market at present, such as various olive essence, elydine essence and azelaic acid essence which are on the market in recent years. Most of the products have a single path, and the addition concentration of a single active matter is pursued, because the physiological path is followed by one surface, the effect cannot be well improved, the symptoms can be repeated, and the problem of the varicella cannot be fundamentally solved.
Disclosure of Invention
The invention aims to provide an oil-controlling and acne-removing composition aiming at the defects that the existing skin care products aiming at the acne muscle cannot fundamentally solve the defects of the acne muscle due to single active ingredient and one-sided physiological channel.
The invention also aims to provide the application of the oil-controlling and acne-clearing composition in skin care products or skin medicaments.
The invention also aims to provide an oil-control acne-clearing skin care product prepared from the oil-control acne-clearing composition.
The invention also aims to provide several product forms of the oil-control acne-clearing skin care product.
The technical scheme adopted for realizing the purpose of the invention is as follows:
a composition for controlling oil and removing pox comprises tetrahydro-methyl pyrimidine carboxylic acid, polylysine, white willow bark extract and yeast/zinc fermentation product;
wherein, the tetrahydro-methyl pyrimidine carboxylic acid has the functions of anti-inflammation, eliminating inflammatory factors, blocking inflammatory reaction and improving the capability of cells for resisting stimulation. The polylysine, especially the tree-shaped polylysine with a special configuration, can be used for inhibiting the reproduction of pathogenic bacterial strains in the acne bacillus in a targeted manner, has no influence on nonpathogenic bacterial strains, and belongs to a component for accurately regulating microecology. The white willow bark extract contains salicin and salicylic acid derivatives, and can be metabolized into salicylic acid in a human body to dissolve sebum and promote sebum removal and epidermal keratinocyte removal; the yeast/zinc fermentation product is rich in zinc, and can regulate sebum secretion and control oil.
The weight ratio of the tetrahydromethylpyrimidine carboxylic acid to the polylysine to the white willow bark extract to the yeast/zinc fermentation product is (0.01-5): (0.00001-0.1): (0.01-3): (0.1-10).
In the technical scheme, the weight ratio of the tetrahydromethylpyrimidine carboxylic acid to the polylysine to the white willow bark extract to the yeast/zinc fermentation product is (0.01-3): (0.0005-0.001): (0.1-1): (0.5-5).
In another aspect of the invention, the oil-controlling and acne-clearing composition is applied to skin care products or skin medicaments.
In another aspect of the invention, an oil-control acne-clearing skin care product comprises the oil-control acne-clearing composition of claim 1 and acceptable auxiliary materials.
In the above technical solution, the acceptable auxiliary materials include one or more of a humectant, a skin conditioner, a thickener, a fragrance, a surfactant, a chelating agent, a buffer, a pH adjuster, and a pigment.
In the above technical solution, the humectant comprises one or more of polyol, polysaccharide, proteins, amino acids, allantoin, hydroxyethyl urea, betaine, hyaluronic acid and its salts, vegetable oil and synthetic oil;
the skin conditioner comprises one or more of SOD, idebene, caffeine, plant extract, algae extract, animal extract, fermentation product, peptide, polyphenol, alkaloid, saponin, flavonoid, trace elements, amino acids, protein, protease, vitamin and its derivatives, silanol and composition on the market; the compound component group on the market comprises one or more of chlorphenamine maleate, Eurol (BT/WHT) and Acnacidol;
the thickening agent comprises one or more of hyaluronic acid, sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, potassium hyaluronate, silanol sodium hyaluronate, sclerotium rolfsii gum, polyglutamic acid, tremella polysaccharide, xanthan gum, carbomer, sodium polyacrylate, glycerol polyacrylate/acrylic acid copolymer and biological carbohydrate gum;
the aromatic is selected from one or more of hydrolat, essential oil, essence and animal and plant and fungus extract;
the chelating agent is EDTA-2 Na;
the buffer is one or a combination of sodium citrate, sodium hydrogen phosphate and disodium hydrogen phosphate;
the pH regulator is one or a combination of tromethamine, triethanolamine, sodium hydroxide and citric acid.
The preparation method of the oil-control acne-clearing skin care product comprises the steps of firstly, mixing acceptable auxiliary materials to obtain a base material system; then cooling the base material system to below 40 ℃, and finally adding the oil-controlling and acne-removing composition.
On the other hand, the invention provides an essence lotion for controlling oil and clearing pox, which comprises, by mass, 100 parts,
on the other hand, the invention provides an oil-control acne-clearing essence milk, which comprises 100 parts by mass,
on the other hand, the invention discloses oil-control acne-removing cream which comprises 100 parts by mass,
on the other hand, the invention discloses an oil-control acne-clearing facial mask, which comprises the following components in 100 parts by mass,
compared with the prior art, the invention has the beneficial effects that:
1. the oil-control acne-clearing composition provided by the invention has the synergistic effect of the four components from the viewpoints of resisting inflammation, regulating skin micro-ecology, regulating sebum secretion and promoting metabolism, and can be used for improving the skin state of the acne muscle in a multi-dimensional manner.
2. The oil-control acne-clearing essence lotion, essence milk, cream and mask provided by the invention can effectively reduce the red area, improve porphyria purpura index, reduce percutaneous water loss index and sebum content, and improve the skin state of acne muscle in multiple dimensions.
Detailed Description
The present invention will be described in further detail with reference to specific examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and do not limit the invention.
Example 1
This example describes 100 parts by mass of an aqueous solution of glycerin prepared from several oil-controlling and pox-clearing compositions, and the effects of the use thereof. The addition amount of glycerol in the glycerol aqueous solution is 5%. The purpose of glycerin is to improve the skin feel upon application, and glycerin does not affect any of the ingredients in the composition.
| Composition 1 | Composition 1' | Composition 2 | Composition 2' | Composition 3 | Composition 3' | Composition 4 | Composition 4' | |
| Tetrahydrophylpyrimidine carboxylic acids | 0.1 | 0.1 | 0.1 | 0.1 | 1 | 1 | 5 | 0 |
| Polylysine | 0.00005 | 0 | 0.0005 | 0.0005 | 0.001 | 0.001 | 0.1 | 0.1 |
| White willow bark extract | 0.2 | 02 | 0.1 | 0 | 1 | 1 | 3 | 3 |
| Yeast/zinc fermentation products | 0.5 | 0.5 | 1 | 1 | 5 | 0 | 10 | 10 |
40 varicella muscle patients were selected as subjects and randomized into 8 groups of 5 persons each. Skin tests were performed on 40 selected varicella muscle patients and the average value of each group was calculated. Each group of subjects respectively use the aqueous solution prepared by the oil-controlling and acne-removing compositions once a day, and the dosage is 1 ml/time. After 28 consecutive days of use, the selected 40 varicella muscle patients were again subjected to skin test, and the rate of change of the bilateral test was calculated. The test results are shown in the following table:
the data results show that compositions 1-4 and 1 '-4' both have significant effects of reducing the area of the red zone, increasing the porphyrinic index, decreasing the transepidermal water loss index, and decreasing the sebum content, but the soothing, repairing, and oil control effects are better when 4 components are added (i.e., compositions 1-4) than compositions 1 '-4'.
From the above table, it can be seen that in the composition formula, although only polylysine is added in one of the components, for example, composition 1 is compared with composition 1', the efficacy is improved more than the change rate of the red area, the porphyria purpura index, the change rate of the percutaneous water loss index and the change rate of the sebum content are greatly improved, and the polylysine can generate synergistic effect with other three substances in the composition. Similarly, the other three substances may act synergistically with the other three substances in the composition. Therefore, the four substances in the invention are mutually cooperated and mutually promoted to achieve the effects of relieving, repairing and controlling oil.
Example 2
An essence lotion for controlling oil and clearing pox, which comprises, by mass, 100 parts,
30 varicella muscle patients were selected as subjects and randomized into 2 groups of 15 persons each. Skin tests were performed on 30 selected varicella muscle patients and the average value of each group was calculated. Each subject used the essence water containing the composition of example 2 and the blank lotion separately, 2 times daily, at a dose of 0.5 ml/time. After 28 consecutive days of use, the skin test was performed again on 30 selected varicella muscle patients, and the rate of change of the test was calculated. The test result shows that the using effect of the oil-control and acne-removing essence water is remarkably improved compared with that of a blank group (namely, the oil-control and acne-removing composition is removed on the basis of the formula of the embodiment). The specific test results are shown in the following table:
example 3
An oil-controlling acne-removing essence milk, which comprises 100 parts by mass,
30 varicella muscle patients were selected as subjects and randomized into 2 groups of 15 persons each. Skin tests were performed on 30 selected varicella muscle patients and the average value of each group was calculated. Each group of subjects used the serum containing the composition of example 3 and the blank emulsion 2 times a day at a dose of 0.5 ml/time. After 28 consecutive days of use, the skin test was performed again on 30 selected varicella muscle patients, and the rate of change of the test was calculated. The test result shows that the using effect of the oil-control and acne-removing essence water is remarkably improved compared with that of a blank group (namely, the oil-control and acne-removing composition is removed on the basis of the formula of the embodiment). The specific test results are shown in the following table:
example 4
An oil-control acne-clearing face cream, 100 parts by mass comprises,
30 varicella muscle patients were selected as subjects and randomized into 2 groups of 15 persons each. Skin tests were performed on 30 selected varicella muscle patients and the average value of each group was calculated. Each subject used the essence cream containing the composition of example 4 and the blank cream separately, 2 times daily, at a dose of 0.3 g/time. After 28 consecutive days of use, the skin test was performed again on 30 selected varicella muscle patients, and the rate of change of the test was calculated. The test result shows that the using effect of the oil-control and acne-removing essence water is remarkably improved compared with that of a blank group (namely, the oil-control and acne-removing composition is removed on the basis of the formula of the embodiment). The specific test results are shown in the following table:
example 5
An oil-controlling acne-removing mask comprises, by mass, 100 parts,
30 varicella muscle patients were selected as subjects and randomized into 2 groups of 15 persons each. Skin tests were performed on 30 selected varicella muscle patients and the average value of each group was calculated. Each group of subjects used the essence mask containing the composition of example 5 and the blank mask separately at a dose of 25 g/mask and 1 mask 2 times per week. After 28 days, the skin test was performed again on 30 selected varicella muscle patients, and the rate of change of the test was calculated. The test result shows that the using effect of the oil-control and acne-removing essence water is remarkably improved compared with that of a blank group (namely, the oil-control and acne-removing composition is removed on the basis of the formula of the embodiment). The specific test results are shown in the following table:
the foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, many modifications and adaptations can be made without departing from the principle of the present invention, and such modifications and adaptations should also be considered as the scope of the present invention.
Claims (11)
1. A composition for controlling oil and removing pox is characterized by comprising tetrahydromethylpyrimidine carboxylic acid, polylysine, white willow bark extract and yeast/zinc fermentation product;
the weight ratio of the tetrahydromethylpyrimidine carboxylic acid to the polylysine to the white willow bark extract to the yeast/zinc fermentation product is (0.01-5): (0.00001-0.1): (0.01-3): (0.1-10).
2. The oil-controlling and pox-clearing composition according to claim 1, wherein the weight ratio of said tetrahydro-methyl-pyrimidine carboxylic acid, polylysine, white willow bark extract and yeast/zinc fermentation product is (0.01-3): (0.0005-0.001): (0.1-1): (0.5-5).
3. Use of the oil-controlling pox-clearing composition according to claim 1 or claim 2 in a skin care or dermatological medicament.
4. An oil-control acne-clearing skin care product, which is characterized by comprising the oil-control acne-clearing composition of claim 1 and acceptable auxiliary materials.
5. The oil-and pox-controlling skin care product according to claim 4 wherein said acceptable excipients include one or more combinations of humectants, skin conditioners, thickeners, fragrances, surfactants, chelating agents, buffers, pH adjusters, and pigments.
6. The oil-and pox-controlling skin care product according to claim 5 wherein said humectant comprises a combination of one or more of polyols, polysaccharides, proteins, amino acids, allantoin, hydroxyethyl urea, betaine, hyaluronic acid and salts thereof, vegetable oils, synthetic oils;
the skin conditioner comprises one or more of SOD, idebene, caffeine, plant extract, algae extract, animal extract, fermentation product, peptides, polyphenols, alkaloids, saponins, flavonoids, trace elements, amino acids, proteins, proteases, vitamins and derivatives thereof, silanols and compounds on the market; the compound component group on the market comprises one or more of chlorphenamine maleate, Eurol (BT/WHT) and Acnacidol;
the thickening agent comprises one or more of hyaluronic acid, sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, potassium hyaluronate, silanol sodium hyaluronate, sclerotium rolfsii gum, polyglutamic acid, tremella polysaccharide, xanthan gum, carbomer, sodium polyacrylate, glycerol polyacrylate/acrylic acid copolymer and biological carbohydrate gum;
the aromatic is selected from one or more of hydrolat, essential oil, essence and animal and plant and fungus extract;
the chelating agent is EDTA-2 Na;
the buffer is one or a combination of sodium citrate, sodium hydrogen phosphate and disodium hydrogen phosphate;
the pH regulator is one or a combination of tromethamine, triethanolamine, sodium hydroxide and citric acid.
7. The method for preparing the oil-controlling and acne-removing skin care product according to any one of claims 4 to 6, wherein acceptable auxiliary materials are firstly mixed to obtain a base material system; then cooling the base material system to below 40 ℃, and finally adding the oil-controlling and acne-removing composition.
8. An essence lotion for controlling oil and clearing pox is characterized in that 100 parts by mass of the essence lotion comprises,
9. an oil-control acne-removing essence emulsion is characterized by comprising, by mass, 100 parts of,
10. an oil-control acne-removing cream is characterized in that 100 parts by mass of the cream comprises,
11. an oil-control acne-clearing facial mask is characterized by comprising, by mass, 100 parts,
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115192484A (en) * | 2022-08-05 | 2022-10-18 | 广州优然生物科技有限公司 | Essence with oil control and acne removal effects and preparation method thereof |
| CN115317427A (en) * | 2022-09-13 | 2022-11-11 | 广州市涵美化妆品有限公司 | Anti-inflammatory repairing composition and preparation method and application thereof |
| CN115919699A (en) * | 2023-01-16 | 2023-04-07 | 广州凡岛网络科技有限公司 | Acne-removing composition and application thereof in cosmetics |
| CN115944551A (en) * | 2023-01-19 | 2023-04-11 | 麦吉丽生物科技有限公司 | Composition and essence with effects of controlling oil, removing acne and removing acne marks and preparation method of composition and essence |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109091433A (en) * | 2018-10-22 | 2018-12-28 | 广州智尚生物科技有限公司 | A kind of composition of oil control and acne removal and its application in cosmetics |
| CN111053887A (en) * | 2019-12-23 | 2020-04-24 | 湖州中科金羿医药科技有限公司 | Composition for resisting propionibacterium acnes and regulating skin microecology and application |
| CN111202700A (en) * | 2020-02-26 | 2020-05-29 | 广州环亚化妆品科技有限公司 | Composition for reducing skin purpurin and preparation method and application thereof |
| CN113749974A (en) * | 2021-10-19 | 2021-12-07 | 北京安德普泰医疗科技有限公司 | Acne-clearing repairing mask and preparation method thereof |
-
2022
- 2022-04-12 CN CN202210380976.0A patent/CN114712283A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109091433A (en) * | 2018-10-22 | 2018-12-28 | 广州智尚生物科技有限公司 | A kind of composition of oil control and acne removal and its application in cosmetics |
| CN111053887A (en) * | 2019-12-23 | 2020-04-24 | 湖州中科金羿医药科技有限公司 | Composition for resisting propionibacterium acnes and regulating skin microecology and application |
| CN111202700A (en) * | 2020-02-26 | 2020-05-29 | 广州环亚化妆品科技有限公司 | Composition for reducing skin purpurin and preparation method and application thereof |
| CN113749974A (en) * | 2021-10-19 | 2021-12-07 | 北京安德普泰医疗科技有限公司 | Acne-clearing repairing mask and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115192484A (en) * | 2022-08-05 | 2022-10-18 | 广州优然生物科技有限公司 | Essence with oil control and acne removal effects and preparation method thereof |
| CN115317427A (en) * | 2022-09-13 | 2022-11-11 | 广州市涵美化妆品有限公司 | Anti-inflammatory repairing composition and preparation method and application thereof |
| CN115919699A (en) * | 2023-01-16 | 2023-04-07 | 广州凡岛网络科技有限公司 | Acne-removing composition and application thereof in cosmetics |
| CN115944551A (en) * | 2023-01-19 | 2023-04-11 | 麦吉丽生物科技有限公司 | Composition and essence with effects of controlling oil, removing acne and removing acne marks and preparation method of composition and essence |
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