CN106309271B

CN106309271B - Special mask liquid for pregnant women and preparation method thereof

Info

Publication number: CN106309271B
Application number: CN201610712400.4A
Authority: CN
Inventors: 黄彩秒; 刘瑞学; 冷群英
Original assignee: Guangdong Bawei Biotechnology Co ltd
Current assignee: Guangdong Bawei Biotechnology Co ltd
Priority date: 2016-08-24
Filing date: 2016-08-24
Publication date: 2021-01-26
Anticipated expiration: 2036-08-24
Also published as: CN106309271A

Abstract

The invention discloses a special mask liquid for pregnant women and a preparation method thereof, aiming at providing a safe, mild and obvious mask liquid for pregnant women with a water replenishing effect; the mask liquid is mainly prepared from the following components in percentage by weight: 6.21-12.46% of basic moisturizing composition, 0.5-6% of mild moisturizing composition, 0.08-0.15% of carbomer, 0.08-0.15% of pH regulator, 0.01-0.05% of disodium EDTA (ethylene diamine tetraacetic acid), 0.5-2% of anti-allergic agent, 0.5-0.9% of preservative and the balance of deionized water; the mild water supplementing composition is at least four of cogongrass rhizome fermentation product, parasitic ginkgo biloba fermentation liquor, atelocollagen, chitosan, oat bran extract and tremella extract; belongs to the technical field of cosmetics.

Description

Special mask liquid for pregnant women and preparation method thereof

Technical Field

The invention provides a mask liquid, in particular to a mask liquid special for pregnant women, and also relates to a preparation method of the mask liquid special for the pregnant women; belongs to the technical field of cosmetics.

Background

The colloquial language has cloud: "lack of skin care during pregnancy equals natural aging for 13 years". During pregnancy, because the secretion of estrogen and lutein is increased, the self-protection and repair functions of the skin of the pregnant woman are rapidly reduced, and the problems of long spots, melanin deposition, dry or oily skin, dark yellow face and the like easily occur. At the same time, the skin of the pregnant woman becomes abnormally sensitive and is difficult to resist the adverse stimulation of external factors such as ultraviolet rays, computer radiation, air pollution and the like.

Therefore, the pregnant women select products which are safe and harmless to the mothers and fetuses and can effectively improve the skin problem in the pregnancy and delivery period, and the pregnant women are particularly important. For women, the basis for skin health is moisture. The skin has the problems of dullness, sensitivity, fragility, roughness, aging, vigorous oil secretion and the like, and the root is caused by water-oil imbalance. Therefore, the pregnant woman uses the mild moisturizing product to adjust the water-oil balance in the pregnancy and delivery period, the natural adjusting capability of the skin is recovered, and the smooth, tender and glossy healthy skin is reproduced.

Disclosure of Invention

Aiming at the problems, the invention aims to provide the special mask liquid for pregnant women, which is safe and mild and has a remarkable water replenishing effect.

The invention also aims to provide a preparation method of the special mask liquid for pregnant women.

In order to achieve the above object, a first technical solution provided by the present invention is as follows:

the mask liquid special for pregnant women is mainly prepared from the following components in percentage by weight: 6.21-12.46% of basic moisturizing composition, 0.5-6% of mild moisturizing composition, 0.08-0.15% of carbomer, 0.08-0.15% of pH regulator, 0.01-0.05% of disodium EDTA (ethylene diamine tetraacetic acid), 0.5-2% of anti-allergic agent, 0.5-0.9% of preservative and the balance of deionized water;

the mild water supplementing composition is at least four of cogongrass rhizome ferment, parasitic fermentation liquor of ginkgo elps, atelocollagen, chitosan, oat bran extract and tremella extract.

Further, the mild moisturizing composition further comprises at least two of cashew extract, spearmint leaf extract, tuberose extract and pullulanase.

Further, the mild moisturizing composition further comprises four compounds of cashew extract, spearmint leaf extract, tuberose extract and pullulanase.

Further, the basic moisturizing composition of the facial mask solution for pregnant women is at least four of allantoin, polyhydric alcohol, polyglutamic acid, sodium hyaluronate, xylitol, dehydrated xylitol, xylitol-based glucoside, glycerol polymethacrylate and hydroxyethyl urea;

furthermore, the facial mask liquid special for pregnant women is prepared from one or any combination of glycerol, polyglycerol-10, butanediol and sorbitol.

Further, in the mask liquid special for pregnant women, the pH regulator is aminomethyl propanol or triethanolamine.

Further, the preservative is a mixture of caprylyl hydroximic acid and 1, 3-propylene glycol, and the ratio of the 1, 3-propylene glycol to the caprylyl hydroximic acid is 80-95: 20-5.

Further, the anti-allergy agent comprises three combinations of a sophora flavescens root extract, a glycyrrhiza inflate root extract and a scutellaria baicalensis root extract.

The latter technical scheme of the invention is to provide a preparation method of the special mask liquid for pregnant women, which comprises the following steps:

1) weighing the components according to the dosage of the formula;

2) slowly adding carbomer into deionized water under stirring, heating and stirring to 80-90 deg.C, keeping the temperature and stirring to completely swell;

3) the step 2) also comprises the preparation of sodium hyaluronate or/and polyglutamic acid solution: slowly adding sodium hyaluronate or/and polyglutamic acid into any polyalcohol while stirring, fully stirring until the mixture is uniformly dispersed, adding 10% metered deionized water, and fully stirring until the solution is in a transparent particle-free state;

4) adding disodium EDTA and the basic moisturizing composition into the step 2), keeping the temperature and stirring until the disodium EDTA and the basic moisturizing composition are completely dissolved, homogenizing for 2-4min, keeping the temperature for 10-15min until the defoaming is completely finished, adding a pH regulator until the pH is 5.5-6.8 when the temperature is reduced to 50-60 ℃, and stirring uniformly;

5) and (4) when the temperature of the substance obtained in the step (4) is reduced to 40-45 ℃, adding the mild moisturizing composition, the anti-allergy agent and the preservative, and uniformly stirring to obtain the mask liquid.

Compared with the prior art, the technical scheme provided by the invention has the following beneficial effects:

(1) the special mask liquid for pregnant women is not added with chemical compositions harmful to skin, does not contain oily components, synthetic surfactant, spice, alcohol, heavy metal, hormone, mineral oil and pigment, and is safe, mild and non-irritant.

(2) At least four of the cogongrass rhizome fermentation product, the parasitic ginkgo biloba fermentation broth, the pullulanase polysaccharide, the atelocollagen, the chitosan, the oat bran extract and the tremella extract in the special mask liquid for the pregnant women have mutual synergistic effect, so that the special mask liquid can soften the skin, increase the content of collagen in the skin, strengthen a skin system, increase the skin elasticity, strengthen a collagen association tissue and promote the formation of a collagen I type; the atelocollagen is an effective carrier of protein, can retain water, eliminate fine lines/wrinkles, have the effects of moisturizing and resisting aging, and can remove chloasma and freckles.

(3) The spearmint leaf extract, the cashew extract and the tuberose extract in the special mask liquid for pregnant women have a strong inhibition effect on hyaluronidase in a synergistic manner, can effectively inhibit the decomposition of hyaluronic acid, condition unclean and blocked skin, improve the dry and water-deficient condition, relieve and relax, effectively and deeply condition the skin problems caused by bad living habits such as staying up at night and the like, and have the effects of relieving and replenishing water and warming and refreshing the skin; meanwhile, the skin whitening cream can also be used as an allergy inhibitor, a skin whitening agent and an antioxidant, can prevent the problems of dark yellow skin, aging and the like, and enables the skin to be transparent and pure from inside to outside.

(4) The preservative adopted in the technical scheme provided by the invention is safe, mild and non-irritant, and has a triple sterilization mechanism. First, organic acids can disrupt the cell membrane of microorganisms, thereby preventing mass exchange; second, chelating iron ions can render microorganisms unable to grow; third, the short carbon chains can break down the cell membrane, allowing the egress of intracellular material.

(5) The anti-allergy agent adopted in the technical scheme provided by the invention is a compound of a sophora flavescens root extract, a glycyrrhiza inflate root extract and a scutellaria baicalensis root extract, can balance grease secretion, dredge and astringe pores, remove endotoxin impurities in skin, can penetrate into the interior of the skin and maintain high activity, effectively inhibits the activity of various enzymes in the melanin generation process, promotes the growth and repair of damaged vascular nerve cells, and has the effects of preventing skin roughness, resisting inflammation and resisting bacteria.

(6) The mild moisturizing composition and the basic moisturizing composition of the mask liquid special for pregnant women are used for synergistically moisturizing, penetrate into the bottom layer of the skin to replenish moisture, repair fine wrinkles of the skin, improve the skin resistance, lock water while moisturizing, promote the skin to recover a good barrier function, effectively reduce water loss, lock water, and keep long-acting moisture for 24 hours, so that the moisture retention, elasticity and flexibility of the skin are enhanced, the skin is carefully nourished, the dryness and pruritus of the skin are relieved, the natural regulation capacity of the skin is recovered, the problems of dull, sensitive, fragile, rough and aging, vigorous grease secretion, looseness and the like of the pregnant women in the gestational and delivery period are well solved, and the skin is enabled to reproduce a smooth, tender and glossy healthy state.

Detailed Description

The technical solution of the present invention is further described below with reference to specific examples, but the present invention is not limited to the following examples. It is noted that, unless otherwise indicated, the various components used in the present invention are all materials known in the art, and are either commercially available or prepared by known methods.

The adopted cogongrass rhizome leavening and ginkgo elps parasiticus fermentation liquor are purchased from ballad Jing chemical Co., Ltd, Guangzhou; pullulanase, atelocollagen, chitosan and tremella fuciformis are purchased from vast Sen International Co., Ltd; oat bran extract was purchased from Huzhou Jiamei biochemicals, Inc.; tuberose extracts were purchased from demi-dian (shanghai) ltd; the extract of leaves of spearmint is purchased from northern economics limited of great khingan; cashew nut extract was purchased from sienna sky biotechnology limited.

Examples 1 to 13 and comparative examples 1 to 3

According to the moisturizing facial mask liquid provided by the invention, based on 100g of the total weight, each group of examples and comparative examples is respectively prepared from the following components in mass number (g), and table 1 is referred to in examples 1 to 8, and table 2 is referred to in examples 9-13 and comparative examples 1-3:

TABLE 1

TABLE 2

The preparation method of the special mask liquid for pregnant women in the above examples 1-13 and comparative examples 1, 2 and 3 comprises the following steps:

1) weighing the components according to the dosage of the formula;

3) preparation of sodium hyaluronate or (and) polyglutamic acid solution: slowly adding sodium hyaluronate or (and) polyglutamic acid into any polyol while stirring, fully stirring until the mixture is uniformly dispersed, adding 10% metered deionized water, and fully stirring until the solution is in a transparent particle-free state;

The facial mask liquid prepared by the invention can be directly applied to the face as an essence liquid, and also can be used for taking out a compressed facial mask or a facial mask towel and pasting the compressed facial mask or the facial mask towel on the face after the compressed facial mask or the facial mask towel is filled in the facial mask or the facial mask towel.

Efficacy test

A first part: evaluation of product safety

(1) Microbiological test item experiments: according to the determination method of the total bacterial count, faecal coliform, staphylococcus aureus, pseudomonas aeruginosa, mould and saccharomycetes of the cosmetic hygiene Specification issued by the ministry of health of the people's republic of China in 2007 and according to the indexes specified by the light industry Standard QB/T2872-plus 2007 of the people's republic of China, the special mask liquid for pregnant women belongs to qualified products.

(2) And (3) testing sanitary chemical inspection projects: according to a method for measuring total mercury, total arsenic and total lead of cosmetic hygiene Specifications issued by the ministry of health of the people's republic of China in 2007 and according to indexes specified by the light industry Standard QB/T2872 plus 2007 of the people's republic of China, the special mask liquid for pregnant women belongs to qualified products.

(3) Skin irritation/corrosivity test: according to the skin irritation/corrosivity classification standard in cosmetic hygiene Specifications issued by the Ministry of health of the people's republic of China in the 3 rd month of 2007, the skin irritation/corrosivity experiment of the special mask liquid for pregnant women belongs to no irritation.

A second part: evaluation of product Effect

Test example 1

Firstly, testing a test article: facial mask liquid special for pregnant women and prepared in examples 1,3, 5, 7, 11 and 13 and comparative examples 1-3

Second, the tested population

Number: pregnant woman and 90 people

Age: between 20 and 40 years old

Health condition: the skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary selection standard of the subject.

Grouping: divided into 9 groups of 10 persons each.

Third, testing method

1. Selecting the left arm and the right arm of the subject to be marked in a circulating mode sequentially: a test area sample group and a blank control area;

2. the technician uses the skin moisture content test Corneometer CM825 for measurement, and the average is taken and recorded as a blank value.

3. After 15 minutes of application of the sample to the test site washed with clear water, the test site was removed and patted.

4. Subjects were measured 5 times by a technician using a skin moisture content test Corneometer CM825 after 0.5h, 1h, 2h, 4h, 6h of sequential application of cosmetics, and averaged.

5. And counting the measured values, and analyzing the change rule of the skin moisture.

Fourth, test results

TABLE 3 moisture content test results

Sample (I)	0h	0.5h	1h	2h	4h	6h
							Blank space	37.60	38.30	37.87	38.67	38.62	39.53
EXAMPLE 1 facial mask solution	37.96	56.50	55.17	53.37	51.80	50.95
							EXAMPLE 3 facial mask solutions	39.40	59.08	57.23	55.57	54.47	53.80
EXAMPLE 5 facial mask solutions	42.43	63.89	62.12	60.77	59.07	57.65
							EXAMPLE 7 facial mask solutions	38.52	59.21	58.03	57.29	56.02	54.28
Example 11 facial mask solutions	38.70	59.80	58.20	57.77	56.83	55.32
							Example 13 facial mask solution	37.60	60.30	59.43	57.50	56.70	55.93
Comparative example 1 facial mask liquid	40.25	60.78	59.36	58.45	57.69	56.02
							Comparative example 2 facial mask liquid	37.68	53.24	51.98	49.53	46.80	45.26
Comparative example 3 facial mask liquid	37.84	50.36	49.07	47.34	46.03	44.16

Table 4 moisture content difference test results

Sample (I)	0h	0.5h	1h	2h	4h	6h
							Blank space	0	0.70	0.27	1.07	1.02	1.93
EXAMPLE 1 facial mask solution	0	18.54	17.21	15.41	13.84	12.99
							EXAMPLE 3 facial mask solutions	0	19.68	17.83	16.17	15.07	14.40
EXAMPLE 5 facial mask solutions	0	21.46	19.69	18.34	16.64	15.22
							EXAMPLE 7 facial mask solutions	0	20.69	19.51	18.77	17.50	15.76
Example 11 facial mask solutions	0	21.10	19.50	19.07	18.13	16.62
							Example 13 facial mask solution	0	22.70	21.83	19.90	19.10	18.33
Comparative example 1 facial mask liquid	0	20.53	19.11	18.20	17.44	15.77
							Comparative example 2 facial mask liquid	0	15.56	14.30	11.85	9.12	7.58
Comparative example 3 facial mask liquid	0	12.52	11.23	9.50	8.19	6.32

Table 5 hydration test results

Sample (I)

0h

0.5h

1h

2h

4h

6h

Blank space

0

1.86％

0.71％

2.84％

2.71％

5.14％

EXAMPLE 1 facial mask solution

0

48.85％

45.34％

40.60％

36.47％

34.23％

EXAMPLE 3 facial mask solutions

0

49.95％

45.25％

41.03％

38.24％

36.55％

EXAMPLE 5 facial mask solutions

0

50.58％

46.41％

43.22％

39.21％

35.86％

EXAMPLE 7 facial mask solutions

0

53.71％

50.65％

48.73％

45.43％

40.91％

Example 11 facial mask solutions

0

54.52％

50.39％

49.27％

46.86％

42.95％

Example 13 facial mask solution

0

60.37％

58.07％

52.93％

50.80％

48.75％

Comparative example 1 facial mask liquid

0

51.01％

47.48％

45.22％

43.33％

39.18％

Comparative example 2 facial mask liquid

0

41.30％

37.95％

31.45％

24.20％

20.12％

Comparative example 3 facial mask liquid

0

33.09％

29.68％

25.11％

21.64％

16.70％

The results show that the moisturizing effect of the facial mask liquid special for pregnant women in examples 1,3, 5, 7, 11 and 13 of the invention is remarkable, after 0.5h, the average moisture difference before and after skin is more than 18%, and after 6h, the average moisture difference before and after skin is still more than 12%, wherein the moisturizing effect of the facial mask liquid special for pregnant women in example 13 is the best, and after 6h, the average moisture difference before and after skin reaches 18.33; meanwhile, the water locking effect of the special mask liquid for pregnant women in the embodiments 1,3, 5, 7, 11 and 13 is good, and the hydration value is still higher than 34% after the mask liquid is used for 6 hours, which shows that the special mask liquid for pregnant women can effectively reduce the skin water loss while replenishing water.

Compared with the mask liquid special for pregnant women in example 13, the average moisture difference value of the mask liquid special for pregnant women in comparative example 1 before and after skin in a test time is lower than that of the mask liquid special for pregnant women in example 13, and the hydration value is also obviously lower than that of the mask liquid special for pregnant women in example 13, which shows that under the same conditions, the water replenishing and water locking effects of the combination of the cogongrass rhizome leavening, the ginkgo mistletoe fermentation liquid, the elaeagnus mollis, the chitosan, the oat bran extract and the tremella extract are not as good as the water replenishing and water locking effects of the combination of the cogongrass rhizome leavening, the ginkgo mistletoe fermentation liquid, the elaeagnus mollis, the chitosan, the oat bran extract and the tremella extract, the spearmint leaf extract, the tuberose extract and the pullulan polysaccharide are not good.

Compared with the mask liquid special for pregnant women in example 13, the average moisture difference value of the mask liquid special for pregnant women in comparative example 2 before and after skin in a test time is lower than that of the mask liquid special for pregnant women in example 13, and the hydration value is also obviously lower than that of the mask liquid special for pregnant women in example 13, which shows that under the same conditions, the moisturizing and water locking effects of the composition of the cashew extract, the spearmint leaf extract, the tuberose extract and the pullulan are not as good as those of the composition of the cashew extract, the spearmint leaf extract, the tuberose extract and the pullulan in the cogongrass rhizome fermentation broth, the atelochia ginica lacking collagen, the chitosan, the oat bran extract and the tremella extract.

Compared with the mask liquid special for pregnant women in the embodiment 13, the average moisture difference value of the mask liquid special for pregnant women in the comparative example 3 before and after the skin within the testing time is lower than that of the mask liquid special for pregnant women in the embodiment 13, and the hydration rate value is also obviously lower than that of the mask liquid special for pregnant women in the embodiment 13, which shows that under the same conditions, the optimal water replenishing and water locking effect obtained by the invention is brought by the compounding and the synergistic effect of ten components of the cogongrass rhizome leavening, the ginkgo elysphytops fermentation broth, the atelocollagen, the chitosan, the oat bran extract, the tremella extract, the cashew extract, the spearmint leaf extract, the tuberose extract and the pullulanase.

Test example 2

Firstly, testing a test article: facial mask liquid special for pregnant women, prepared in examples 4, 6, 10 and 13 and comparative examples 1, 2 and 3

Second, the tested population

Number: pregnant woman and 140

Age: between 20 and 40 years old

Grouping: divided into 7 groups of 20 people each.

Thirdly, a testing method: after each group of testees clean the face, the special facial mask liquid for the pregnant women is lightly applied to the face until the face is completely attached, and the facial mask liquid is applied for 15 minutes and used for 2 times per week. The using time is one month.

Fourth, test the assessment results

TABLE 6 EXAMPLE 4 trial evaluation results of pregnant woman-specific mask solutions

TABLE 7 EXAMPLE 6 trial evaluation results of the facial mask solution specific for pregnant women

TABLE 8 EXAMPLE 10 trial evaluation results of pregnant woman-specific facial mask solutions

TABLE 9 EXAMPLE 13 trial evaluation results of pregnant woman-specific mask solutions

TABLE 10 trial evaluation results of facial mask solutions specific for pregnant women in comparative examples 1, 2, and 3

The results show that the evaluation results of the facial mask liquid special for pregnant women in examples 4, 6, 10 and 13 and comparative example 1 are relatively higher than those in comparative examples 2 and 3, and the mild moisturizing composition disclosed by the invention can penetrate into the bottom layer of the skin to replenish moisture, repair fine wrinkles of the skin, improve the resistance of the skin, lock water while moisturizing, promote the skin to recover a good barrier function, effectively reduce moisture loss, lock water, and keep 24-hour long-acting moisture, so that the moisture retention, elasticity and flexibility of the skin are enhanced, the skin is finely nourished, the dryness and pruritus of the skin are relieved, the natural regulating capacity of the skin is recovered, and the skin problems of dullness, sensitivity, fragility, roughness and aging, vigorous oil secretion, looseness and the like of the pregnant women in the gestational and labor period are well solved.

Claims

1. The mask liquid special for pregnant women is characterized by being prepared from the following components in percentage by weight: 12.46% of a basic moisturizing composition, 6% of a mild moisturizing composition, 0.15% of carbomer, 0.15% of pH regulator, 0.05% of EDTA disodium, 2% of anti-allergy agent, 0.9% of preservative and the balance of deionized water;

the basic moisturizing composition is prepared by mixing allantoin, polyhydric alcohol, polyglutamic acid, sodium hyaluronate, xylitol-based glucoside, glycerol polymethacrylate and hydroxyethyl urea according to a mass ratio of 0.4:8:0.03:0.03:1:2: 1; the polyol is prepared by mixing xylitol, dehydrated xylitol, glycerol, polyglycerol-10, butanediol and sorbitol according to the mass ratio of 0.4:0.6:2:2:2: 1;

the mild moisturizing composition is prepared from a cogongrass rhizome fermentation product, a parasitic ginkgo biloba fermentation broth, atelocollagen, chitosan, an oat bran extract, a tremella extract, a cashew extract, a spearmint leaf extract, a tuberose extract and pullulan according to a mass ratio of 0.4:0.5:0.2:0.3:1.5:2:0.3:0.3:0.2: 0.3;

the anti-allergy agent is prepared by mixing a sophora flavescens root extract, a liquorice root extract and a scutellaria root extract according to a mass ratio of 0.8:0.6: 0.6;

the preservative is a mixture of caprylyl hydroximic acid and 1, 3-propylene glycol, and the ratio of the 1, 3-propylene glycol to the caprylyl hydroximic acid is 80-95: 20-5.

2. The special mask liquid for pregnant women according to claim 1, wherein the pH regulator is triethanolamine.

3. A method for preparing a facial mask liquid special for pregnant women according to claim 2, comprising the steps of:

1) weighing the components according to the dosage of the formula;

3) the step 2) also comprises the preparation of sodium hyaluronate and polyglutamic acid solution: slowly adding sodium hyaluronate and polyglutamic acid into any polyol while stirring, fully stirring until the mixture is uniformly dispersed, adding 10% metered deionized water, and fully stirring until the solution is in a transparent particle-free state;

4) adding EDTA disodium, the basic moisturizing composition except the sodium hyaluronate, the polyglutamic acid and the polyhydric alcohol in the step 3) into the step 2), keeping the temperature and stirring until the EDTA disodium and the basic moisturizing composition are completely dissolved, homogenizing for 2-4min, keeping the temperature for 10-15min until the defoaming is completely finished, adding a pH regulator until the pH value is 5.5-6.8 when the temperature is reduced to 50-60 ℃, and stirring uniformly;

5) when the temperature of the substance obtained in the step 4) is reduced to 40-45 ℃, adding the mild moisturizing composition, the anti-allergy agent and the preservative, and uniformly stirring to obtain the mask liquid.