CN107397704A - It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect - Google Patents
It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect Download PDFInfo
- Publication number
- CN107397704A CN107397704A CN201710874640.9A CN201710874640A CN107397704A CN 107397704 A CN107397704 A CN 107397704A CN 201710874640 A CN201710874640 A CN 201710874640A CN 107397704 A CN107397704 A CN 107397704A
- Authority
- CN
- China
- Prior art keywords
- extract
- facial mask
- etiolation
- adopting
- hydrogenated starch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 61
- 230000001815 facial effect Effects 0.000 title claims abstract description 42
- 230000026535 de-etiolation Effects 0.000 title claims abstract description 31
- 230000000694 effects Effects 0.000 title claims abstract description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 36
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 36
- 240000003421 Dianthus chinensis Species 0.000 claims abstract description 29
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 27
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 27
- -1 glycosyl trehalose Chemical compound 0.000 claims abstract description 27
- 229920001908 Hydrogenated starch hydrolysate Polymers 0.000 claims abstract description 26
- 241000195493 Cryptophyta Species 0.000 claims abstract description 19
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims abstract description 19
- 229960000401 tranexamic acid Drugs 0.000 claims abstract description 19
- 235000011187 glycerol Nutrition 0.000 claims abstract description 18
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims abstract description 16
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 16
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 16
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 16
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 16
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 15
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229960001631 carbomer Drugs 0.000 claims abstract description 15
- 108010009736 Protein Hydrolysates Proteins 0.000 claims abstract description 13
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000004744 fabric Substances 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 13
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 6
- 229920000742 Cotton Polymers 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000008367 deionised water Substances 0.000 claims description 2
- 229910021641 deionized water Inorganic materials 0.000 claims description 2
- 239000008213 purified water Substances 0.000 claims description 2
- 240000008397 Ganoderma lucidum Species 0.000 claims 1
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 abstract description 4
- 239000003814 drug Substances 0.000 description 10
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 8
- 208000003251 Pruritus Diseases 0.000 description 7
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 240000005001 Paeonia suffruticosa Species 0.000 description 5
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 230000003020 moisturizing effect Effects 0.000 description 5
- 230000000770 proinflammatory effect Effects 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 241000699666 Mus <mouse, genus> Species 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 229960001660 histamine phosphate Drugs 0.000 description 4
- ZHIBQGJKHVBLJJ-UHFFFAOYSA-N histamine phosphate Chemical compound OP(O)(O)=O.OP(O)(O)=O.NCCC1=CNC=N1 ZHIBQGJKHVBLJJ-UHFFFAOYSA-N 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 230000001139 anti-pruritic effect Effects 0.000 description 3
- 239000003908 antipruritic agent Substances 0.000 description 3
- 210000005069 ears Anatomy 0.000 description 3
- 240000006409 Acacia auriculiformis Species 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 206010027146 Melanoderma Diseases 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 2
- 229960003957 dexamethasone Drugs 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 150000004702 methyl esters Chemical class 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229920000433 Lyocell Polymers 0.000 description 1
- 244000137852 Petrea volubilis Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000012109 statistical procedure Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 229960004418 trolamine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
There is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect the invention discloses a kind of, said composition is made up of following components in percentage by weight:Butanediol 3.0 7.0%, glycerine 2.0 8.0%, the mixture 1.5 7.0% of glycosyl trehalose and hydrogenated starch hydrolysate, Ovshinsky marine algae extract 0.5 1.0%, carbomer 0.1 0.3%, triethanolamine 0.1 0.3%, tranexamic acid 0.1 2.0%, methyl hydroxybenzoate 0.06 0.15%, Sodium Hyaluronate 0.06 0.15%, China pink extract and moutan root bark extract 1.0 2.5%, Ganodenna Lucidum P.E 0.02 0.07%, methylisothiazolinone 0.008 0.01%, water surplus, wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, the Mixing ratio by weight example of China pink extract and moutan root bark extract is 4:6.The present composition can replenishing water and preserving moisture, conditioning skin, improve the colour of skin, the dark yellow state of adjustment, make skin water profit, brilliant white, flexible.
Description
Technical field
The invention belongs to technical field of skin care, has the smooth bright group for adopting de-etiolation qigong effect more particularly, to a kind of
Compound and its facial mask.
Background technology
At present, the cosmetics of the pollution of environment, ultraviolet irradiation, bad daily life system custom and poor quality all can be right
Skin causes damage, and is deposited in greasy, the old cutin and dirt of skin surface if do not disposed in time, if things go on like this will
Oozing to skin internal layer makes skin become coarse dark yellow, tarnishes and elasticity.
The content of the invention
The purpose of the present invention be improve pachylosis it is dark yellow, it is matt and elastic the problem of, there is provided one kind have smoothness it is bright
Adopt the composition of de-etiolation qigong effect, can replenishing water and preserving moisture, conditioning skin, improve the colour of skin, the dark yellow state of adjustment, make skin water profit,
It is brilliant white, flexible.
There is the smooth bright facial mask for adopting de-etiolation qigong effect it is a further object of the present invention to provide a kind of.
The purpose of the present invention is achieved in the following ways:
It is a kind of that there is the smooth bright composition for adopting de-etiolation qigong effect, it is characterised in that said composition is by following weight percent
The component of ratio is made, and the percentage by weight sum of following each component is 100%:
Butanediol 3.0-7.0%,
Glycerine 2.0-8.0%,
The mixture 1.5-7.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-1.0%,
Carbomer 0.1-0.3%,
Triethanolamine 0.1-0.3%,
Tranexamic acid 0.1-2.0%,
Methyl hydroxybenzoate 0.06-0.15%,
Sodium Hyaluronate 0.06-0.15%,
China pink extract and moutan root bark extract 1.0-2.5%,
Ganodenna Lucidum P.E 0.02-0.07%,
Methylisothiazolinone 0.008-0.01%,
Water surplus,
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and tree peony root
The Mixing ratio by weight example of bark extract is 4:6.
Above-mentioned to have the smooth bright composition for adopting de-etiolation qigong effect, preferably said composition is by following components in percentage by weight
It is made:
Butanediol 4.0-6.0%,
Glycerine 2.0-5.0%,
The mixture 2.0-5.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-0.9%,
Carbomer 0.1-0.2%,
Triethanolamine 0.1-0.2%,
Tranexamic acid 0.1-1.0%,
Methyl hydroxybenzoate 0.1-0.15%,
Sodium Hyaluronate 0.1-0.15%,
The mixture 1.0-2.0% of China pink extract and moutan root bark extract,
Ganodenna Lucidum P.E 0.02-0.05%,
Methylisothiazolinone 0.009-0.01%,
Water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and tree peony root
The Mixing ratio by weight example of bark extract is 4:6.
Above-mentioned have a smooth bright composition for adopting de-etiolation qigong effect, more preferably said composition by following percentage by weight group
Divide and be made:
Butanediol 5.0%,
Glycerine 4.0%,
The mixture 3.5% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.8%,
Carbomer 0.15%,
Triethanolamine 0.15%,
Tranexamic acid 1.0%,
Methyl hydroxybenzoate 0.1%,
Sodium Hyaluronate 0.1%,
The mixture 1.5% of China pink extract and moutan root bark extract,
Ganodenna Lucidum P.E 0.05%,
Methylisothiazolinone 0.0095%,
Water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and tree peony root
The Mixing ratio by weight example of bark extract is 4:6.
Above-mentioned to have the smooth bright composition for adopting de-etiolation qigong effect, described butanediol is 1,3-BDO.
Above-mentioned to have the smooth bright composition for adopting de-etiolation qigong effect, described water is purified water or deionized water.
It is described have the smooth bright composition for adopting de-etiolation qigong effect can prepare smooth bright adopt should in de-etiolation gas skin care item
With.Described smooth bright de-etiolation gas skin care item of adopting adopt de-etiolation gas facial mask for smoothness is bright.
It is described it is smooth it is bright adopt de-etiolation gas facial mask, the facial mask includes film cloth and facial mask base fluid, wherein, facial mask base fluid be by with
Lower composition is prepared:
Butanediol 3.0-7.0%,
Glycerine 2.0-8.0%,
The mixture 1.5-7.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-1.0%,
Carbomer 0.1-0.3%,
Triethanolamine 0.1-0.3%,
Tranexamic acid 0.1-2%,
Methyl hydroxybenzoate 0.06-0.15%,
Sodium Hyaluronate 0.06-0.15%,
China pink extract and moutan root bark extract 1.0-2.5%,
Ganodenna Lucidum P.E 0.02-0.07%,
Methylisothiazolinone 0.008-0.01%, water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and tree peony root
The Mixing ratio by weight example of bark extract is 4:6.
It is preferred that facial mask base fluid is to be prepared from the following components:
Butanediol 4.0-6.0%,
Glycerine 2.0-5.0%,
The mixture 2.0-5.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-0.9%,
Carbomer 0.1-0.2%,
Triethanolamine 0.1-0.2%,
Tranexamic acid 0.1-1.0%,
Methyl hydroxybenzoate 0.1-0.15%,
Sodium Hyaluronate 0.1-0.15%,
The mixture 1.0-2.0% of China pink extract and moutan root bark extract,
Ganodenna Lucidum P.E 0.02-0.05%,
Methylisothiazolinone 0.009-0.01%, water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and tree peony root
The Mixing ratio by weight example of bark extract is 4:6.
The described smooth bright film cloth for adopting de-etiolation gas facial mask is that material is non-woven fabrics, silk fiber, tencel fiber, plant fibre
It is any in dimension, jam fiber, pure cotton cloth, preferably pure cotton cloth.
The bright preparation method for adopting de-etiolation gas facial mask of above-mentioned smoothness comprises the following steps:Take butanediol, glycerine, glycosyl trehalose
It is transparent with the mixture of hydrogenated starch hydrolysate, Ovshinsky marine algae extract, carbomer, triethanolamine, tranexamic acid, methyl hydroxybenzoate
Matter acid sodium, China pink extract and moutan root bark extract, Ganodenna Lucidum P.E, methylisothiazolinone, add water to 100% mixing system
Into facial mask liquid, facial mask cloth is immersed in facial mask liquid and taken out, is produced.
Beneficial effects of the present invention:The present invention is pressed using China pink extract and moutan root bark extract combination Ganodenna Lucidum P.E
Compound to obtain the composition of polynary effect according to specific ratio, the active ingredient cooperative compensating contained in each effect component, obtain
More efficient utilization.On the one hand, China pink extract and moutan root bark extract, Synergistic, skin itching, cusalgia are effectively alleviated
With the symptom of inflammatory allergic, enhancing skin resists power to extraneous sensible factor, hence it is evident that the allergy rate of sensitive skin is reduced, with this
In combination with Ganodenna Lucidum P.E and Ovshinsky marine algae extract, moisturizing and improvement skin sense, make skin soft glossy.Tranexamic acid adds
Add, because its affinity with skin is high, readily permeable cuticula simultaneously gos deep into skin and played a role, promote other anti-inflammatory activities into
The absorption divided.The present invention also includes a variety of potent moisturizings and water lock composition:Butanediol, glycerine, glycosyl trehalose and hydrogenated starch
Mixture, Ovshinsky marine algae extract, Sodium Hyaluronate, the Ganodenna Lucidum P.E of hydrolysate, various active moisturizing ingredient cooperate,
Pass through the osmosis of tranexamic acid so that skin obtains sufficient nutrition, continues moisturizing and skin care, is effectively improved dry water shortage
Property skin, has the function that deeply preserving moisture Glycerin;The tranexamic acid of addition, not only act synergistically, increase with above-mentioned moisturizing ingredient
Strong penetration, the basalis for the skin that can go directly, moreover it is possible to suppress the confusion of blackspot position epidermal cell function, thoroughly break off because ultraviolet
The approach that the melanin that line irradiates and formed occurs, allows blackspot no longer to thicken, expand, and improves dim mute and matt skin quality, makes flesh
Skin is pale.Therefore, the smooth bright composition for adopting de-etiolation qigong effect of the invention being capable of replenishing water and preserving moisture, conditioning skin, the improvement colour of skin, tune
Whole dark yellow state, make skin water profit, brilliant white, flexible.
Embodiment
The present invention is further described below by way of specific embodiment:Wherein, polyoses content in Ganodenna Lucidum P.E
More than 30% (in terms of glucan), China pink extract are purchased from Shaanxi Rui Kang bioengineering Co., Ltd, moutan root bark extract
Purchased from Xi'an Yuan Sen bio tech ltd, Ovshinsky marine algae extract is purchased from the limited public affairs of Shaanxi Si Nuote biotechnologys
Department.
Embodiment 1
Take 1,3-BDO 3.0%, glycerine 2.5%, mixture (the weight ratio of glycosyl trehalose and hydrogenated starch hydrolysate
Example 3:1) 2.0%, Ovshinsky marine algae extract 0.5%, carbomer 0.15%, triethanolamine 0.15%, tranexamic acid 0.3%, oxybenzene
Mixture (the part by weight 4 of methyl esters 0.06%, Sodium Hyaluronate 0.06%, China pink extract and moutan root bark extract:6)
1.0%, Ganodenna Lucidum P.E 0.02%, methylisothiazolinone 0.008%, add water to 100%.
Embodiment 2
Take 1,3-BDO 7.0%, glycerine 8.0%, mixture (the weight ratio of glycosyl trehalose and hydrogenated starch hydrolysate
Example 3:1) 3.0%, Ovshinsky marine algae extract 1.0%, carbomer 0.3%, triethanolamine 0.3%, tranexamic acid 1.0%, oxybenzene first
Mixture (the part by weight 4 of ester 0.15%, Sodium Hyaluronate 0.15%, China pink extract and moutan root bark extract:6)
2.5%, Ganodenna Lucidum P.E 0.07%, methylisothiazolinone 0.01%, add water to 100%.
Embodiment 3
Take 1,3-BDO 5.0%, glycerine 4.0%, mixture (the weight ratio of glycosyl trehalose and hydrogenated starch hydrolysate
Example 3:1) 3.5%, Ovshinsky marine algae extract 0.8%, carbomer 0.15%, triethanolamine 0.15%, tranexamic acid 1.0%, oxybenzene
Mixture (the part by weight 4 of methyl esters 0.1%, Sodium Hyaluronate 0.1%, China pink extract and moutan root bark extract:6)
1.5%, Ganodenna Lucidum P.E 0.05%, methylisothiazolinone 0.0095%, 100% is added water to, is mixed and made into facial mask liquid, face
Film cloth, which is immersed in facial mask liquid, to be produced.Described film cloth is pure cotton cloth.
Embodiment 4
Take 1,3-BDO 3.0%, glycerine 3.0%, mixture (the weight ratio of glycosyl trehalose and hydrogenated starch hydrolysate
Example 3:1) 3.5%, Ovshinsky marine algae extract 1.0%, carbomer 0.1%, triethanolamine 0.1%, tranexamic acid 0.6%, oxybenzene first
Mixture (the part by weight 4 of ester 0.15%, Sodium Hyaluronate 0.08%, China pink extract and moutan root bark extract:6)
1.0%, Ganodenna Lucidum P.E 0.07%, methylisothiazolinone 0.008%, water surplus, facial mask liquid is mixed and made into, facial mask cloth is soaked
Enter in facial mask liquid and produce.Described film cloth is non-woven fabrics.
Facial mask liquid obtained by embodiment 3 is subjected to pharmacology test
Test example 1
1. animal:Mouse 30 (every group 10), male and female half and half, 20~25g of body weight.
2. medicine:The facial mask base fluid of the embodiment of the present invention 3
3. Dexamethasone Cream (30g:22.5mg):Three nine-day periods after the winter solstice medicine company (positive drug)
4. dimethylbenzene:Traditional Chinese medicines Reagent Company (modeling type reagent)
Influence to mice auricle swelling
1.1. packet:Mouse is randomly divided into 3 groups:Model group (dimethylbenzene group), positive group of (30g:22.5mg), composition group
Three dosage groups of stoste.
1.2. experimental method:
1.2.1 proinflammatory agent is prepared:100% dimethylbenzene
1.2.2 composition or positive drug are dissolved in proinflammatory agent, positive drug 0.03mg/ml, and composition 0.1m stostes/
ml。
1.2.3 two sided coatings proinflammatory agent (model group) or positive drug or facial mask liquid are contained before and after the auris dextra of experiment mice
Proinflammatory agent, proinflammatory agent volume be 0.02ml only.Left ear is without any processing.
1.2.4 after 4 hours, Animal Anesthesia is put to death, ears 9mm diameters card punch is cut and is beaten respectively with same position
Lower circular hole piece, weighs.
1.2.5 it is swelling again that left auricle is subtracted per mouse auris dextra sheet weight.By control group and the swelling degree of administration group
Carry out statistical procedures.
1.3 result:Compared with model group, composition group can substantially reduce Mice Auricle inflammation, have highly significant, carry
Show that said composition has good antiinflammatory action.
Influence of the table 1 to mice auricle swelling
Compared with model group, * P<0.05;**P<0.01
Test two antipruritic experiments
1. animal:Cavy 30 (every group 10), male and female half and half, body weight 300g.
2. medicine:The facial mask liquid of the embodiment of the present invention 3
3. histamine phosphate:National Institute for Food and Drugs Control 150510-201313
4. Dexamethasone Cream (30g:22.5mg):Three nine-day periods after the winter solstice medicine company 115011019H# (positive drug)
Histamine phosphate's system is itched the influence of reaction
1.1. packet:Mouse is randomly divided into 3 groups:Blank control group (distilled water), positive group of (30g:22.5mg), composition
Three dosage groups of group (stoste).
1.2. experimental method:The previous day is tested, to instep behind each group cavy right side, coating combination is once.In experimental day, use
Behind the group sand paper scratch animal right side at the shaving of instep, about 1cm2Scope or so, then in this place spread compositions once, blank control group
Equivalent distilled water is given, after 10 minutes, starts to drip 0.01%, 0.02%, 0.03% at wound face, 0.04% ... is incremented by
Concentration, it is 0.05ml/ every time, until cavy occur later licks right metapedes, when later licking right metapedes finally to there is cavy
The histamine phosphate total amount given is itch-threshold, and record compares each group itch-threshold.
1.3 result:Compared with blank control group, composition group and positive group can improve cavy itch-threshold, have notable
Sex differernce, said composition is prompted to have good itching-relieving action.
Table 2 causes the influence of reaction of itching to histamine phosphate
Compared with model group, * P<0.05;**P<0.01
Test example 3
Illustrate the effect of the present invention below by way of specific clinical test example:
Using the facial mask of embodiment 3 as test sample, choosing have dry skin, it is coarse it is dark yellow, there is anaphylaxis pruritis, but without table
The damaged people of volunteer 50 of skin tries out, and the age is 25~40 years old.Before subject sleeps daily after cleaning skin, the facial mask is spread on into face
Portion 15-20 minutes, then with clear water cleaning skin, 2 times a week, 3 weeks are 1 cycle.After 3 weeks, statistical result shows:Skin is obvious
Feel that water profit brilliant white is antipruritic, flexible, smooth fine and smooth and unfruitful to be without allergic symptom, 45 antipruritic people, effective percentage 90%
5 people, account for 10%.Therefore, facial mask of the present invention can replenishing water and preserving moisture, conditioning skin, improve the colour of skin, the dark yellow state of adjustment, make skin
It is water profit, brilliant white, flexible, and above-mentioned person on probation has no stimulation, and does not produce any side effect and adverse reaction.
Claims (10)
1. a kind of have the smooth bright composition for adopting de-etiolation qigong effect, it is characterised in that said composition is by following percentage by weight
Component be made:
Butanediol 3.0-7.0%,
Glycerine 2.0-8.0%,
The mixture 1.5-7.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-1.0%,
Carbomer 0.1-0.3%,
Triethanolamine 0.1-0.3%,
Tranexamic acid 0.1-2.0%,
Methyl hydroxybenzoate 0.06-0.15%,
Sodium Hyaluronate 0.06-0.15%,
China pink extract and moutan root bark extract 1.0-2.5%,
Ganodenna Lucidum P.E 0.02-0.07%,
Methylisothiazolinone 0.008-0.01%,
Water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and moutan root bark carry
The Mixing ratio by weight example for taking thing is 4:6.
2. according to claim 1 have the smooth bright composition for adopting de-etiolation qigong effect, it is characterised in that said composition by
Following components in percentage by weight is made:
Butanediol 4.0-6.0%,
Glycerine 2.0-5.0%,
The mixture 2.0-5.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-0.9%,
Carbomer 0.1-0.2%,
Triethanolamine 0.1-0.2%,
Tranexamic acid 0.1-1.0%,
Methyl hydroxybenzoate 0.1-0.15%,
Sodium Hyaluronate 0.1-0.15%,
The mixture 1.0-2.0% of China pink extract and moutan root bark extract,
Ganodenna Lucidum P.E 0.02-0.05%,
Methylisothiazolinone 0.009-0.01%,
Water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and moutan root bark carry
The Mixing ratio by weight example for taking thing is 4:6.
3. according to claim 1 or 2 have the smooth bright composition for adopting de-etiolation qigong effect, it is characterised in that described
Butanediol is 1,3-BDO.
4. according to claim 1 or 2 have the smooth bright composition for adopting de-etiolation qigong effect, it is characterised in that described
Water is purified water or deionized water.
5. being protected with the smooth bright composition for adopting de-etiolation qigong effect in the smooth bright de-etiolation gas of adopting of preparation described in claim 1 or 2
Application in skin product.
6. application according to claim 5, it is characterised in that described smooth bright de-etiolation gas skin care item of adopting are adopted for smoothness is bright
De-etiolation gas facial mask.
7. smooth described in a kind of claim 6 bright adopts de-etiolation gas facial mask, it is characterised in that the facial mask includes film cloth and facial mask base
Liquid, wherein, facial mask base fluid is to consist of to be prepared:
Butanediol 3.0-7.0%,
Glycerine 2.0-8.0%,
The mixture 1.5-7.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-1.0%,
Carbomer 0.1-0.3%,
Triethanolamine 0.1-0.3%,
Tranexamic acid 0.1-2.0%,
Methyl hydroxybenzoate 0.06-0.15%,
Sodium Hyaluronate 0.06-0.15%,
China pink extract and moutan root bark extract 1.0-2.5%,
Ganodenna Lucidum P.E 0.02-0.07%,
Methylisothiazolinone 0.008-0.01%, water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and moutan root bark carry
The Mixing ratio by weight example for taking thing is 4:6.
8. smoothness according to claim 7 is bright to adopt de-etiolation gas facial mask, it is characterised in that the facial mask includes film cloth and facial mask base
Liquid, wherein, facial mask base fluid is to be prepared from the following components:
Butanediol 4.0-6.0%,
Glycerine 2.0-5.0%,
The mixture 2.0-5.0% of glycosyl trehalose and hydrogenated starch hydrolysate,
Ovshinsky marine algae extract 0.5-0.9%,
Carbomer 0.1-0.2%,
Triethanolamine 0.1-0.2%,
Tranexamic acid 0.1-1.0%,
Methyl hydroxybenzoate 0.1-0.15%,
Sodium Hyaluronate 0.1-0.15%,
The mixture 1.0-2.0% of China pink extract and moutan root bark extract,
Ganodenna Lucidum P.E 0.02-0.05%,
Methylisothiazolinone 0.009-0.01%, water surplus;
Wherein, the Mixing ratio by weight example of glycosyl trehalose and hydrogenated starch hydrolysate is 3:1, China pink extract and moutan root bark carry
The Mixing ratio by weight example for taking thing is 4:6.
9. smooth according to claim 7 or 8 bright adopts de-etiolation gas facial mask, it is characterised in that described film cloth is pure cotton cloth.
A kind of 10. smooth bright preparation method for adopting de-etiolation gas facial mask described in claim 7 or 8, it is characterised in that this method bag
Include following steps:Take butanediol, glycerine, the mixture of glycosyl trehalose and hydrogenated starch hydrolysate, Ovshinsky marine algae extract, card
Ripple nurse, triethanolamine, tranexamic acid, methyl hydroxybenzoate, Sodium Hyaluronate, China pink extract and moutan root bark extract, ganoderma lucidum extraction
Thing, methylisothiazolinone, add water to 100% and be mixed and made into facial mask liquid, facial mask cloth is immersed in facial mask liquid and taken out, is produced.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710874640.9A CN107397704A (en) | 2017-09-25 | 2017-09-25 | It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710874640.9A CN107397704A (en) | 2017-09-25 | 2017-09-25 | It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107397704A true CN107397704A (en) | 2017-11-28 |
Family
ID=60388882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710874640.9A Pending CN107397704A (en) | 2017-09-25 | 2017-09-25 | It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107397704A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108478469A (en) * | 2018-06-27 | 2018-09-04 | 孙涛 | A kind of pole profit moisturizing Face-protecting mask |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104188874A (en) * | 2014-09-18 | 2014-12-10 | 湖南御家化妆品制造有限公司 | Mild moisturizing facial mask |
CN104814920A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Yellow-removing whitening mask solution, manufacturing method and yellow-removing whitening mask |
CN106309271A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Facial mask liquid exclusively for pregnant women and preparing method thereof |
CN107184486A (en) * | 2017-07-06 | 2017-09-22 | 曾万祥 | A kind of facial mask liquid and the facial mask containing the facial mask liquid |
-
2017
- 2017-09-25 CN CN201710874640.9A patent/CN107397704A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104188874A (en) * | 2014-09-18 | 2014-12-10 | 湖南御家化妆品制造有限公司 | Mild moisturizing facial mask |
CN104814920A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Yellow-removing whitening mask solution, manufacturing method and yellow-removing whitening mask |
CN106309271A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Facial mask liquid exclusively for pregnant women and preparing method thereof |
CN107184486A (en) * | 2017-07-06 | 2017-09-22 | 曾万祥 | A kind of facial mask liquid and the facial mask containing the facial mask liquid |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108478469A (en) * | 2018-06-27 | 2018-09-04 | 孙涛 | A kind of pole profit moisturizing Face-protecting mask |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN110897901B (en) | Skin-care mask liquid with multiple moisturizing effects and preparation method thereof | |
CN105560155B (en) | Cosmetic composition and its application containing Goat Milk | |
CN108113894A (en) | A kind of infant's activity milky lotion and preparation method thereof | |
CN109549893A (en) | A kind of preparation method with anti-blue light contamination and the composition repaired and essence cream and its essence cream | |
CN105997633A (en) | Traditional Chinese medicine mask prepared from herba dendrobii | |
CN112315890B (en) | Whitening and skin-brightening composition and preparation method and application thereof | |
CN109223618A (en) | A kind of hyaluronic acid Essence and preparation method thereof | |
CN104814901B (en) | One kind prevention striae of pregnancy gel and preparation method thereof | |
CN105395407A (en) | Moisturizing and anti-aging essence and moisturizing and anti-aging cosmetic mainly containing ocean materials | |
CN106176379A (en) | A kind of cosmetics, its preparation method and application | |
CN106420491A (en) | Multifunctional skin care product with effects of whitening skin, removing freckles, preserving moisture and removing wrinkle and preparation method of multifunctional skin care product | |
CN106606444A (en) | Nursing film with whitening and compacting functions | |
CN112263528A (en) | Collagen jelly mask and preparation and use methods thereof | |
CN108309817A (en) | A kind of whitening mask Essence and preparation method thereof using resveratrol | |
CN107550786A (en) | A kind of composition and its facial mask with replenishing water and preserving moisture effect | |
CN106063770B (en) | A kind of gel pad pasting containing growth factor and preparation method thereof | |
CN105362129A (en) | Facial mask liquid containing folium artemisiae argyi extracting solution and preparation method of facial mask liquid | |
CN107397704A (en) | It is a kind of that there is the smooth bright composition and its facial mask for adopting de-etiolation qigong effect | |
CN107468593A (en) | A kind of composition and its facial mask of effect of being releived with moisturizing | |
CN108451842A (en) | Air permeable humidity retaining facial mask and preparation method thereof | |
CN104473855A (en) | Face-lifting cleansing milk containing traditional Chinese medicinal materials | |
CN107496253A (en) | A kind of composition and its facial mask with deep layer cleaning effect | |
CN106726756A (en) | One kind repairs hair film and preparation method thereof | |
CN111840134A (en) | Shampoo free of silicone oil, cationic polymer, sulfate and preservative and preparation method thereof | |
CN107412083A (en) | A kind of composition and its facial mask with skin whitening, moisturizing effect |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171128 |
|
RJ01 | Rejection of invention patent application after publication |