CN114569507A

CN114569507A - Moisturizing emulsion and preparation method thereof

Info

Publication number: CN114569507A
Application number: CN202210246151.XA
Authority: CN
Inventors: 王平
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-03-14
Filing date: 2022-03-14
Publication date: 2022-06-03

Abstract

The invention discloses a moisturizing emulsion and a preparation method thereof, wherein the moisturizing emulsion comprises the following raw materials: glycerol, 1, 2-pentanediol, allantoin, nicotinamide, jojoba oil, carbomer, dipotassium glycyrrhizinate, glyceryl monostearate, xanthan gum, p-hydroxyacetophenone, behenyl alcohol, water-soluble vitamin E, a whitening humectant and the balance of water. The moisturizing emulsion prepared by adding the whitening humectant still has good moisturizing performance within 10 hours after use, and simultaneously has good whitening effect.

Description

Moisturizing emulsion and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to a moisturizing emulsion and a preparation method thereof.

Background

The most basic requirement for skin care is skin moisturization. The stratum corneum of human skin is mainly composed of anucleate keratin filaments, keratinocytes, amino acid compounds and natural moisturizing factors, and has the functions of retaining moisture, a barrier and the like. The water source in the stratum corneum of the skin is mainly sweat secreted by sweat glands, and 20% of water is tightly bound to natural moisturizing factors and skin lipids, so that the formed sebum membrane emulsified by sweat and water and the natural moisturizing factors become two most important factors for skin moisturizing.

The factors causing the skin to lack water mainly comprise two aspects, firstly, environmental factors bring about the skin lack of water, such as autumn and winter, dry weather can cause the moisture of the horny layer to evaporate rapidly, and dry wind can also take away a large amount of moisture in the skin. In addition, in autumn and winter, the metabolism of human body is slowed down in cold weather, the blood flow speed is slowed down, the grease secreted by sebaceous glands is reduced, the moisture supplement of skin is slowed down, the supplement of sebaceous membranes is insufficient, the water locking capacity of skin is weakened, and the problem of skin dryness is caused. Therefore, it is very important to use a cosmetic having a good water-retaining effect on the skin.

The Chinese invention patent (application number: 202110624915.X) discloses a moisturizing emulsion and a preparation method thereof, wherein the emulsion comprises components of jojoba oil, white pond flower seed oil, trehalose, panthenol, astaxanthin, resveratrol, a palmate kelp extract, tranexamic acid, a grape seed extract, a chlorella extract, a chamomile extract, a sea fennel extract, tetrahydromethylpyrimidine carboxylic acid, acetyl hexapeptide-8, allantoin, bisabolol, dipotassium glycyrrhizinate, a sweet orange peel extract and the like. The skin care cream has the effects of deeply preserving water, moisturizing, nourishing and repairing the skin and the like, and can help the skin to establish a self-protection barrier and isolate various stimulations of the external environment. Although the moisturizing emulsion prepared by the invention has a good moisturizing effect, the moisturizing liquid has poor water locking performance, can only maintain the skin to have good moisturizing performance within a short time of smearing, and can still cause the skin to be dry when used in autumn and winter in dry weather, so that the problem of moisturizing is not fundamentally solved.

Disclosure of Invention

Aiming at the defects in the prior art, the invention provides a moisturizing emulsion and a preparation method thereof.

In order to solve the technical problems, the invention adopts the technical scheme that:

a moisturizing emulsion comprises the following raw materials: glycerol, 1, 2-pentanediol, allantoin, nicotinamide, jojoba oil, carbomer, dipotassium glycyrrhizinate, glyceryl monostearate, xanthan gum, p-hydroxyacetophenone, behenyl alcohol, water-soluble vitamin E, a whitening humectant and the balance of water.

Preferably, the material composition comprises the following raw materials in percentage by mass: 2-6 wt% of glycerol, 1-5 wt% of 1, 2-pentanediol, 0.1-0.3 wt% of allantoin, 1-4 wt% of nicotinamide, 2-8 wt% of jojoba oil, 0.1-0.5 wt% of carbomer, 0.5-1.5 wt% of dipotassium glycyrrhizinate, 0.1-1 wt% of glyceryl monostearate, 0.5-2 wt% of xanthan gum, 0.01-0.1 wt% of p-hydroxyacetophenone, 0.25-0.4 wt% of behenyl alcohol, 0.2-0.5 wt% of water-soluble vitamin E, 1-8 wt% of whitening humectant and the balance of water.

The invention adopts the glycerol, the 1, 2-pentanediol and the jojoba oil to improve the moisturizing effect; the water-soluble fullerene is a long-acting free radical scavenger, forms a stable state after absorbing free radicals, has strong oxidation resistance, has the effects of whitening and preventing ultraviolet rays, and can be stored in the skin care product for a long time due to the stability of the water-soluble fullerene; the dipotassium glycyrrhizinate is used as a penetration enhancer and can effectively promote the absorption of effective active substances, so that various substances in the cosmetic composition containing the penetration enhancer can be effectively absorbed by percutaneous penetration, and the cosmetic composition has good effects of resisting ultraviolet radiation, whitening, removing freckles, moisturizing, locking water and improving skin barrier; the xanthan gum can lock human body moisture and prevent human body moisture loss, the water locking and moisture preserving are carried out synchronously, and the skin care product containing the xanthan gum has obvious lubrication feeling and good hand feeling when being smeared; after being applied to the skin, a layer of film can be formed on the surface of the skin, so that the skin can generate good smooth feeling and moist feeling, and the protective effect on the skin is achieved; the nicotinamide can inhibit melanin deposition, prevent melanin from transferring to surface cells, accelerate cutin exfoliation containing melanin, reduce protein yellowing after saccharification, reduce spot size and quantity, and reduce oil secretion; allantoin has effects of promoting cell growth and promoting wound healing; the water-soluble vitamin E can play a role in repairing and locking water and improve the water retention of skin.

Whitening humectant: the rose and the green plum are used as fermentation raw materials of the ferment, the green plum is rich in SOD enzyme, the rapid fermentation of the rose can be effectively promoted, meanwhile, certain oxygen can be provided for aerobic bacteria, the fermentation time is accelerated, the fermentation period is shortened, the content of active substances in fermentation liquor is improved, and the rose and the green plum are cooperatively used to achieve good whitening and moisturizing effects; the fermentation liquor contains rich antioxidant substances such as flavone and polyphenol and rich nutrient components, has good anti-radiation and anti-oxidation effects, can reduce the damage of free radicals generated by the induction of ultraviolet rays and chemical substances to skin tissues, thereby playing the role of delaying senility, and simultaneously the enzyme solution can inhibit the activity of tyrosinase, prevent the formation of melanin and whiten the skin.

The rose ferment has the effects of tonifying qi and blood, beautifying and protecting skin and the like. However, the preparation of pure rose ferment still has some problems: the rose ferment fermentation process has longer period; the flavone in the rose ferment is easy to oxidize at high temperature, so that the content of the flavone and polyphenol in the rose ferment is extremely low; therefore, in order to improve the fermentation period of the rose ferment, improve the fermentation quality of the rose ferment and increase the content of active substances, the green plums are used as auxiliary materials to be fermented together with the roses to shorten the fermentation period, and the antioxidant retinol and/or resveratrol are added, so that the retinol has good antioxidant and anti-aging effects and has the function of promoting the synthesis of collagen; meanwhile, the resveratrol has the effects of oxidation resistance and inflammation resistance, and the three components have synergistic interaction, so that the whitening effect is improved together. The reason is that the rose extract contains antioxidant substances such as flavone, has good anti-radiation and anti-oxidation effects, can reduce the damage of free radicals generated by the induction of ultraviolet rays and chemical substances to skin tissues, inhibit the activity of tyrosinase, and prevent the formation of melanin; the green plums and the roses contain polyphenol substances, have good tyrosinase inhibition activity and are effective tyrosinase inhibitors. Meanwhile, the rose and the green plum can play respective functions and can play a role in synergy.

The plant enzyme can increase the moisture retention and water retention of the skin after being added, the plant enzyme liquid is easy to be absorbed by the skin, has good moisture and water retention effects on the facial skin, does not generate greasy feeling when being used, and is dry and comfortable after being used; due to the ingenious matching of the components, the skin care product can penetrate into the bottom layer of the skin, effectively resist a dry environment, recover the elastic and lusterless skin and moisten and tender the skin, so that the skin care product has the effects of moisturizing, protecting the skin and brightening the skin, and has safety and no irritation to the skin of a human body.

The preparation method of the whitening humectant comprises the following steps:

s1, cleaning rose and green plum, drying, crushing, and sieving with a 80-120 mesh sieve to obtain mixed powder; the mass ratio of the rose to the green plum is (1-5) to 1; mixing 30-50 parts by weight of the mixed powder, 0.5-2 parts by weight of zymophyte, 0.5-3 parts by weight of glucose and 10-30 parts by weight of sterile water, sterilizing at 130 ℃ of 115-30 min, putting into a fermentation tank for sealed fermentation, fermenting at 30-50 ℃ for 1-4 days, and fermenting at 25-35 ℃ for 3-6 days; filtering, and sterilizing the filtrate to obtain the plant enzyme;

s2, mixing 30-50 parts by weight of the plant enzyme and 3-8 parts by weight of the antioxidant uniformly, and stirring for 5-10min at 400-800rpm to obtain the whitening humectant.

The rose enzyme is easy to deteriorate, and an oxidant is usually added or the rose enzyme is wrapped to prevent the rose enzyme from deteriorating; meanwhile, as the retinol is used as a main component in the antioxidant skin conditioner, the retinol has larger irritation to the skin due to the direct use of the retinol, even if the retinol is used in combination with other components, when the retinol is applied to the surface of the skin, the retinol compound and other components in the product directly act on the skin, and users with sensitive skin are easy to have adverse reactions such as dry skin, desquamation, pruritus and the like due to larger irritation; resveratrol is also very poor in water solubility and also has poor effect on skin directly. Therefore, in order to prevent the rose ferment from deteriorating, improve the utilization rate of the resveratrol and reduce the stimulation effect of the retinol on the skin, the inventor wraps the active substances by using the grafted hyaluronic acid film, and utilizes the receptor binding effect of the HA to enable the active substances to stay outside the skin or slowly release the active ingredients in the skin, so as to increase the storage of the active ingredients outside the cuticle, in the cuticle and in the dermis.

The active ingredient is wrapped inside the grafted hyaluronic acid film to form an inclusion, so that the stability of the active ingredient in a system can be improved, and a higher addition amount is achieved; the product permeability can be increased, the product can better permeate into the deep skin and generate better retention, the time for exerting the effect is longer, and the bioavailability is higher; can also reduce the irritation caused by the direct contact of the functional components and the skin, and the prepared product is safer.

Preferably, the preparation method of the whitening moisturizer comprises the following steps:

s1, cleaning and drying rose and green plum, crushing, and sieving with a 80-120 mesh sieve to obtain mixed powder; the mass ratio of the rose to the green plum is (1-5) to 1; mixing 30-50 parts by weight of the mixed powder, 0.5-2 parts by weight of zymophyte, 0.5-3 parts by weight of glucose and 10-30 parts by weight of sterile water, sterilizing at 130 ℃ of 115-30 min, putting into a fermentation tank for sealed fermentation, fermenting at 30-50 ℃ for 1-4 days, and fermenting at 25-35 ℃ for 3-6 days; filtering, and sterilizing the filtrate to obtain the plant enzyme; uniformly mixing 30-50 parts by weight of plant enzyme and 3-8 parts by weight of antioxidant, and stirring at 400-800rpm for 5-10min to obtain the whitening active matter;

s2, adding 3-7 parts by weight of hyaluronic acid into 40-60 parts by weight of PBS solution with pH7.4, stirring at 500rpm of 300-;

s3, pouring 30-50 parts by weight of the whitening active substance into 5-10 parts by weight of the grafted hyaluronic film, and homogenizing for 0.5-3min under the homogenizing pressure of 30-80MPa and the homogenizing speed of 300-; and (3) placing the liposome emulsion in ultrasonic power of 400-.

The antioxidant is retinol and/or resveratrol, preferably, the antioxidant is prepared from the following components in percentage by mass (2-5): (1-3).

The fermentation bacteria are at least one of lactobacillus bulgaricus and lactobacillus plantarum, preferably, the fermentation bacteria are prepared from lactobacillus bulgaricus and lactobacillus plantarum according to the mass ratio of (1-5): (1-3).

The invention simultaneously utilizes sodium alginate and hydroxypropyl-beta-cyclodextrin as membrane carriers, utilizes the hydroxypropyl-beta-cyclodextrin to have certain conditioning and repairing effects on skin, has certain hygroscopicity, has no irritation on muscle, can reduce the irritation of organic molecules in cosmetics to skin mucosa tissues, enhances the stability of effective components, and prevents volatilization and oxidation of nutritional components; the sodium alginate has good hydrophilic performance, has good moisturizing performance on skin, has high viscosity in an aqueous solution, can effectively wrap active substances to achieve the aim of slow release, can effectively improve the utilization rate of the active substances by synergistic use of the sodium alginate and the aqueous solution, and can improve the technical effects of moisturizing, whitening and anti-aging of the skin.

The membrane carrier is sodium alginate and/or hydroxypropyl-beta-cyclodextrin; preferably, the membrane carrier is prepared from sodium alginate and hydroxypropyl-beta-cyclodextrin according to the mass ratio of (1-3): (1-5).

The preparation method of the moisturizing emulsion comprises the following steps:

s1, weighing the raw materials in parts by weight;

s2, uniformly mixing water, water-soluble vitamin E, dipotassium glycyrrhizinate, nicotinamide, allantoin and xanthan gum, and stirring at 1200-1500rpm and 60-70 ℃ for 10-30min to obtain a mixture A;

s3, uniformly mixing glycerol, 1, 3-pentanediol, p-hydroxyacetophenone, glyceryl monostearate, jojoba oil and behenyl alcohol, and stirring at the speed of 900-1400rpm and the temperature of 70-80 ℃ for 10-30min to obtain a mixture B;

s4, adding the mixture B into an emulsification and homogenization device, adding the mixture A, homogenizing for 10-20S at a homogenization pressure of 50-150MPa and a homogenization speed of 3000-5000rpm, cooling, adding carbomer and whitening humectant, and stirring for 15-40min at 200-400rpm, normal temperature and 600-1000rpm to obtain an emulsion C;

s5, homogenizing the emulsion C for 2-5min by using an ultrahigh pressure homogenizer, wherein the homogenizing pressure is 120-200MPa, and the homogenizing speed is 10000-15000rpm, so as to obtain the moisturizing emulsion.

The invention has the beneficial effects that: according to the whitening and skin-whitening composition, the plant type whitening agent (rose ferment) and the whitening agent for chemical whitening (retinol and resveratrol) act on skin through the whitening and moisturizing agent, so that a good whitening and synergistic effect is achieved, and the whitening and skin-whitening composition has the effects of enhancing and whitening, inhibiting melanin and fading color spots. The lipid carrier inclusion loaded with the whitening agent can also be used as an important whitening and moisturizing effective component, is widely applied to various skin care cosmetic fields, such as different formulations of cosmetics such as cream, emulsion and facial mask, and improves different effects of whitening, moisturizing, anti-aging, wrinkle removal and the like.

Detailed Description

The above summary of the present invention is described in further detail below with reference to specific embodiments, but it should not be understood that the scope of the above subject matter of the present invention is limited to the following examples.

Introduction of some raw materials in this application:

2-chloro-1-methylpyridinium iodide, CAS No.: 14338-32-0.

The lactobacillus bulgaricus is purchased from the Chinese medical bacteria preservation management center, and the strain number is as follows: CMCC 34104.

The lactobacillus plantarum is purchased from China agricultural microorganism strain preservation management center, and the strain number is as follows: ACCC 11118.

Example 1

The moisturizing emulsion is prepared from the following raw materials in percentage by mass: 4 wt% of glycerol, 3 wt% of 1, 2-pentanediol, 0.15 wt% of allantoin, 2 wt% of nicotinamide, 5 wt% of jojoba oil, 0.3 wt% of carbomer, 1 wt% of dipotassium glycyrrhizinate, 0.5 wt% of glyceryl monostearate, 1 wt% of xanthan gum, 0.05 wt% of p-hydroxyacetophenone, 0.3 wt% of behenyl alcohol, 0.4 wt% of water-soluble vitamin E, 5 wt% of whitening humectant and the balance of water.

The preparation method of the whitening humectant comprises the following steps: uniformly mixing 3.5 parts by weight of retinol and 1.5 parts by weight of resveratrol, and stirring at 600rpm for 8min to obtain the whitening humectant.

s1, weighing the raw materials in parts by weight;

s2, uniformly mixing water, water-soluble vitamin E, dipotassium glycyrrhizinate, nicotinamide, allantoin and xanthan gum, and stirring at 1300rpm and 65 ℃ for 25min to obtain a mixture A;

s3, uniformly mixing glycerol, 1, 3-pentanediol, p-hydroxyacetophenone, glyceryl monostearate, jojoba oil and behenyl alcohol, and stirring at 1000rpm and 75 ℃ for 15min to obtain a mixture B;

s4, adding the mixture B into an emulsifying and homogenizing device, adding the mixture A, homogenizing for 16S under the homogenizing pressure of 100MPa and the homogenizing speed of 4500rpm, cooling, adding carbomer and a whitening humectant, and stirring for 30min at 300rpm and normal temperature of 800rpm to obtain an emulsion C;

and S5, homogenizing the emulsion C for 3min by using an ultrahigh pressure homogenizer, wherein the homogenizing pressure is 160MPa, and the homogenizing speed is 12000rpm, so as to obtain the moisturizing emulsion.

Example 2

s1, cleaning and drying rose and green plum, crushing, and sieving with a 100-mesh sieve to obtain mixed powder; the mass ratio of the roses to the green plums is 4: 1; mixing 40 parts by weight of the mixed powder, 1 part by weight of zymophyte, 1 part by weight of glucose and 15 parts by weight of sterile water, sterilizing at 121 ℃ for 20min, sealing and fermenting in a fermentation tank, fermenting at 40 ℃ for 3 days, and fermenting at 30 ℃ for 5 days; filtering, and sterilizing the filtrate to obtain the plant enzyme; the fermentation bacteria are prepared from lactobacillus bulgaricus and lactobacillus plantarum according to the mass ratio of 3: 2, preparing a composition;

s2, uniformly mixing 40 parts by weight of the plant enzyme, 3.5 parts by weight of retinol and 1.5 parts by weight of resveratrol, and stirring at 600rpm for 8min to obtain the whitening moisturizer.

s1, weighing the raw materials in parts by weight;

s4, adding the mixture B into an emulsifying and homogenizing device, adding the mixture A, homogenizing for 16S under the homogenizing pressure of 100MPa and the homogenizing speed of 4500rpm, cooling, adding carbomer and a whitening humectant, and stirring at 300rpm and 800rpm for 30min at normal temperature to obtain an emulsion C;

Example 3

s1, cleaning and drying rose and green plum, crushing, and sieving with a 100-mesh sieve to obtain mixed powder; the mass ratio of the roses to the green plums is 4: 1; mixing 40 parts by weight of the mixed powder, 1 part by weight of zymophyte, 1 part by weight of glucose and 15 parts by weight of sterile water, sterilizing at 121 ℃ for 20min, sealing and fermenting in a fermentation tank, fermenting at 40 ℃ for 3 days, and fermenting at 30 ℃ for 5 days; filtering, and sterilizing the filtrate to obtain the plant enzyme; uniformly mixing 40 parts by weight of the plant enzyme, 3.5 parts by weight of retinol and 1.5 parts by weight of resveratrol, and stirring at 600rpm for 8 min; obtaining the whitening active substance; the fermentation bacteria are prepared from lactobacillus bulgaricus and lactobacillus plantarum according to the mass ratio of 3: 2, preparing a composition;

s2, adding 4 parts by weight of hyaluronic acid into 50 parts by weight of PBS solution with pH value of 7.4, stirring at 400rpm for 20min, adding 0.5 part by weight of triethylamine, 3 parts by weight of 2-chloro-1-methylpyridinium iodide and 5 parts by weight of sodium alginate, continuing stirring for 48h, dialyzing after the reaction is finished, freeze-drying, dissolving the obtained grafted hyaluronic acid into 50 parts by weight of absolute ethyl alcohol, and rotationally evaporating at 40 ℃ and 50rpm for 4h to obtain a grafted hyaluronic film;

s3, pouring 40 parts by weight of the whitening active substances into 8 parts by weight of the grafted hyaluronic film, and homogenizing at a homogenizing pressure of 50MPa and a homogenizing speed of 4500rpm for 1min to obtain liposome emulsion; and (3) putting the liposome emulsion into ultrasonic power of 500W for ultrasonic treatment for 10min, and taking out to obtain the whitening humectant.

s1, weighing the raw materials in parts by weight;

Example 4

s1, cleaning and drying rose and green plum, crushing, and sieving with a 100-mesh sieve to obtain mixed powder; the mass ratio of the roses to the green plums is 4: 1; mixing 40 parts by weight of the mixed powder, 1 part by weight of zymophyte, 1 part by weight of glucose and 15 parts by weight of sterile water, sterilizing at 121 ℃ for 20min, sealing and fermenting in a fermentation tank, fermenting at 40 ℃ for 3 days, and fermenting at 30 ℃ for 5 days; filtering, and sterilizing the filtrate to obtain plant enzyme; uniformly mixing 40 parts by weight of the plant enzyme, 3.5 parts by weight of retinol and 1.5 parts by weight of resveratrol, and stirring at 600rpm for 8 min; obtaining the whitening active substance; the fermentation bacteria are prepared from lactobacillus bulgaricus and lactobacillus plantarum according to the mass ratio of 3: 2, preparing a composition;

s2, adding 4 parts by weight of hyaluronic acid into 50 parts by weight of PBS solution with pH value of 7.4, stirring at 400rpm for 20min, adding 0.5 part by weight of triethylamine, 3 parts by weight of 2-chloro-1-methylpyridinium iodide and 5 parts by weight of hydroxypropyl-beta-cyclodextrin, continuing stirring for 48h, dialyzing after the reaction is finished, freeze-drying, dissolving the obtained grafted hyaluronic acid into 50 parts by weight of absolute ethyl alcohol, and rotationally evaporating at 40 ℃ and 50rpm for 4h to obtain a grafted hyaluronic film;

s1, weighing the raw materials in parts by weight;

Example 5

s2, adding 4 parts by weight of hyaluronic acid into 50 parts by weight of PBS solution with pH value of 7.4, stirring at 400rpm for 20min, adding 0.5 part by weight of triethylamine, 3 parts by weight of 2-chloro-1-methylpyridinium iodide, 3 parts by weight of hydroxypropyl-beta-cyclodextrin and 2 parts by weight of sodium alginate, continuing stirring for 48h, dialyzing after the reaction is finished, freeze-drying, dissolving the obtained grafted hyaluronic acid into 50 parts by weight of absolute ethyl alcohol, and rotationally evaporating at 40 ℃ and 50rpm for 4h to obtain a grafted hyaluronic film;

s1, weighing the raw materials in parts by weight;

s5, homogenizing the emulsion C for 3min by using an ultrahigh pressure homogenizer, wherein the homogenizing pressure is 160MPa, and the homogenizing speed is 12000rpm, so as to obtain the moisturizing emulsion.

Test example 1

Evaluation of moisture retention property: the moisturizing emulsions of examples 1-5 were applied evenly to the face of 50 persons 30-40 years old with dry skin or those believed to have dry skin. Before application, the skin moisture content of each subject was measured with a skin moisture tester as a reference value before application. The moisture content of the skin after 1h, 5h and 10h after smearing is measured, 5 groups of the same component are tested, the average value is taken, and the measurement result is shown in table 1.

The principle of the determination method is as follows: the moisturizing performance was determined by measuring the water ionicity in the skin epidermis using a sensor, the measurement results were expressed as numerical values, and the moisture content was calculated.

TABLE 1 evaluation results of moisture retention Properties

From the above results, it is understood that the moisturizing emulsion prepared according to the present invention has a good moisturizing effect, and significantly increases the moisture of the skin before application. The plant enzyme can increase the effects of moisturizing and locking the skin after being added, the plant enzyme liquid is easy to be absorbed by the skin, has good moisturizing and water-retaining effects on the facial skin, does not generate greasy feeling when being used, and is dry and comfortable after being used; the plant enzyme can penetrate into the bottom layer of the skin, effectively resist a dry environment, recover the elastic and lusterless skin and moisten and tender the skin, so that the skin care cream has the functions of moisturizing, skin care and whitening, and has safety and no irritation to the skin of a human body. Example 3, active ingredients such as plant enzymes and antioxidants are wrapped inside the grafted hyaluronic acid film to form a wrapping body, so that the stability of the active ingredients in a system can be improved, and a higher addition amount is achieved; the product permeability can be increased, the product can better permeate into the deep skin and generate better retention, the efficacy-exerting time is longer, the bioavailability is higher, and the moisturizing performance of the skin is further improved; can also reduce the irritation caused by the direct contact of the functional components and the skin, and the prepared product is safer. Example 5 sodium alginate and hydroxypropyl-beta-cyclodextrin are used as membrane carriers, hydroxypropyl-beta-cyclodextrin is used to have certain conditioning and repairing effects on skin, certain hygroscopicity is achieved, no irritation is caused to muscles, irritation of organic molecules in cosmetics to skin mucosa tissues can be reduced, stability of active ingredients is enhanced, and volatilization and oxidation of nutritional ingredients are prevented; the sodium alginate has good hydrophilic performance and good moisturizing performance on skin, the aqueous solution of the sodium alginate has high viscosity, active substances can be effectively wrapped, the aim of slow release is achieved, the sodium alginate and the aqueous solution of the sodium alginate are used cooperatively, the utilization rate of the active substances can be effectively improved, and the moisturizing and hydrating effects on the skin can be improved.

Test example 2

Tyrosinase inhibition assay: firstly, preparing a 0.1mol/l PBS solution with the pH value of 6.86, and dissolving a sample to be detected in a PBS buffer solution to prepare a solution of the sample to be detected with the concentration of 0.5 mg/mL; dissolving L-tyrosine in PBS buffer solution to prepare 1 mmol/L-tyrosine solution; dissolving tyrosinase in PBS buffer solution to prepare 50U/mL tyrosinase solution; adding 0.5mL of tyrosinase solution and 1.5mL of LPBS buffer solution into 0.5mL of sample solution to be tested, preserving the temperature for 10min at 37 ℃, adding 0.5mL of L-tyrosine solution, continuing to react for 18min, measuring the light absorption value at 475nm, testing 5 groups of the same component, taking the average value, and obtaining the test result shown in Table 2.

Tyrosinase inhibition (%) [1- (a1-a2)/(A3-a4) ] × 100

Wherein, A1: l-tyrosine, the light absorption value of the sample to be detected and the tyrosinase system; a2: the light absorption value of the sample to be detected, the tyrosinase and PBS buffer solution system; a3: the light absorption values of an L-tyrosine and tyrosinase system and a PBS buffer solution; a4: and (3) the light absorption value of a tyrosinase and PBS buffer solution system.

TABLE 2 tyrosinase inhibition

	Tyrosinase inhibition ratio (%)
		Example 1	55.6
Example 2	83.5
		Example 5	88.3

From the above results, it is known that adding a whitening agent to a moisturizing lotion can increase the tyrosinase inhibition rate, reduce the generation of melanin, and have whitening and antioxidant effects. The rose and green plum enzyme added in the embodiment 2 can significantly improve the tyrosinase inhibition rate, so that the whitening effect is improved, and the rose extract contains antioxidant substances such as flavone and the like, has good anti-radiation and anti-oxidation effects, can reduce the damage of free radicals generated by ultraviolet and chemical substance induction on skin tissues, can inhibit the activity of tyrosinase, and can prevent melanin from forming; the green plum and the rose contain polyphenol substances, have good tyrosinase inhibition activity, and are effective tyrosinase inhibitors. Meanwhile, the rose and the green plum can play respective functions and can play a role in synergy.

Claims

1. The moisturizing emulsion is characterized by comprising the following raw materials: glycerol, 1, 2-pentanediol, allantoin, nicotinamide, jojoba oil, carbomer, dipotassium glycyrrhizinate, glyceryl monostearate, xanthan gum, p-hydroxyacetophenone, behenyl alcohol, water-soluble vitamin E, a whitening humectant and the balance of water.

2. The moisturizing emulsion of claim 1, comprising the following raw materials in percentage by mass: 2-6 wt% of glycerol, 1-5 wt% of 1, 2-pentanediol, 0.1-0.3 wt% of allantoin, 1-4 wt% of nicotinamide, 2-8 wt% of jojoba oil, 0.1-0.5 wt% of carbomer, 0.5-1.5 wt% of dipotassium glycyrrhizinate, 0.1-1 wt% of glyceryl monostearate, 0.5-2 wt% of xanthan gum, 0.01-0.1 wt% of p-hydroxyacetophenone, 0.25-0.4 wt% of behenyl alcohol, 0.2-0.5 wt% of water-soluble vitamin E, 1-8 wt% of whitening humectant and the balance of water.

3. The moisturizing emulsion according to claim 1 or 2, wherein the preparation method of the whitening moisturizer comprises the following steps:

s1, cleaning rose and green plum, drying, crushing and sieving to obtain mixed powder; mixing the above mixed powder, zymophyte, glucose and sterile water, sterilizing, sealing in a fermentation tank, fermenting at 30-50 deg.C for 1-4 days, and fermenting at 25-35 deg.C for 3-6 days; filtering, and sterilizing the filtrate to obtain the plant enzyme;

s2, mixing and stirring the plant enzyme and the antioxidant to obtain the whitening moisturizer.

4. The moisturizing emulsion of claim 3, wherein the preparation method of the whitening moisturizer comprises the following steps:

s1, cleaning rose and green plum, drying, crushing and sieving to obtain mixed powder; mixing the above mixed powder, zymocyte, glucose and sterile water, sterilizing, sealing in a fermentation tank, fermenting at 30-50 deg.C for 1-4 days, and fermenting at 25-35 deg.C for 3-6 days; filtering, and sterilizing the filtrate to obtain plant enzyme; mixing and stirring plant enzyme and antioxidant to obtain whitening active matter;

s2, adding hyaluronic acid into the PBS solution, stirring, adding triethylamine, 2-chloro-1-methylpyridinium iodide and a membrane carrier, continuing stirring for 36-64h, dialyzing after the reaction is finished, freeze-drying, dissolving the obtained grafted hyaluronic acid in absolute ethyl alcohol, and performing rotary evaporation to obtain a grafted hyaluronic film;

s3, pouring the whitening active substance into the grafted hyaluronic film for homogenization to obtain liposome emulsion; and carrying out ultrasonic treatment on the liposome emulsion to obtain the whitening humectant.

5. The moisturizing emulsion of claim 4, wherein the antioxidant is at least one of retinol and resveratrol.

6. The moisturizing emulsion according to claim 3 or 4, wherein the mass ratio of the rose flowers to the green plums is (1-5): 1.

7. The moisturizing emulsion of claim 3 or 4, wherein the fermentation bacteria are at least one of Lactobacillus bulgaricus and Lactobacillus plantarum.

8. The moisturizing emulsion of claim 4, wherein the membrane carrier is hydroxypropyl- β -cyclodextrin and/or sodium alginate.

9. A method of preparing a moisturising emulsion according to any one of claims 1 to 8, characterised in that it consists of:

s1, weighing the raw materials in parts by weight;

s2, uniformly mixing and stirring water, water-soluble vitamin E, dipotassium glycyrrhizinate, nicotinamide, allantoin and xanthan gum to obtain a mixture A;

s3, uniformly mixing and stirring glycerol, 1, 3-pentanediol, p-hydroxyacetophenone, glyceryl monostearate, jojoba oil and behenyl alcohol to obtain a mixture B;

s4, adding the mixture B into an emulsifying and homogenizing device, adding the mixture A for homogenizing, cooling, adding carbomer and a whitening humectant, and stirring to obtain an emulsion C;

and S5, homogenizing the emulsion C by using an ultrahigh pressure homogenizer to obtain the moisturizing emulsion.