CN116211723B - Nourishing and moisturizing lotion and preparation method thereof - Google Patents
Nourishing and moisturizing lotion and preparation method thereof Download PDFInfo
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- CN116211723B CN116211723B CN202310364745.5A CN202310364745A CN116211723B CN 116211723 B CN116211723 B CN 116211723B CN 202310364745 A CN202310364745 A CN 202310364745A CN 116211723 B CN116211723 B CN 116211723B
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- lycopene
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- nourishing
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- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 66
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 239000006210 lotion Substances 0.000 title claims description 17
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims abstract description 65
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims abstract description 65
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims abstract description 65
- 229960004999 lycopene Drugs 0.000 claims abstract description 65
- 235000012661 lycopene Nutrition 0.000 claims abstract description 65
- 239000001751 lycopene Substances 0.000 claims abstract description 65
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims abstract description 65
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 60
- 239000000839 emulsion Substances 0.000 claims abstract description 40
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 36
- 235000013336 milk Nutrition 0.000 claims abstract description 27
- 239000008267 milk Substances 0.000 claims abstract description 27
- 210000004080 milk Anatomy 0.000 claims abstract description 27
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 19
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 19
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 19
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims abstract description 19
- 240000001548 Camellia japonica Species 0.000 claims abstract description 18
- 235000018597 common camellia Nutrition 0.000 claims abstract description 18
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229940032094 squalane Drugs 0.000 claims abstract description 18
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 18
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- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 30
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 30
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 30
- 239000006185 dispersion Substances 0.000 claims description 22
- 235000019198 oils Nutrition 0.000 claims description 20
- 238000002156 mixing Methods 0.000 claims description 18
- 238000009210 therapy by ultrasound Methods 0.000 claims description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 15
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- 238000001816 cooling Methods 0.000 claims description 13
- 239000002994 raw material Substances 0.000 claims description 13
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 239000000243 solution Substances 0.000 claims description 10
- 238000006243 chemical reaction Methods 0.000 claims description 9
- 229940075507 glyceryl monostearate Drugs 0.000 claims description 9
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 7
- 229940119170 jojoba wax Drugs 0.000 claims description 7
- 230000007935 neutral effect Effects 0.000 claims description 7
- 239000002244 precipitate Substances 0.000 claims description 7
- 238000001556 precipitation Methods 0.000 claims description 7
- 238000005406 washing Methods 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 6
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 claims description 6
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 claims description 6
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 claims description 5
- 239000012346 acetyl chloride Substances 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 240000007594 Oryza sativa Species 0.000 claims description 4
- 235000007164 Oryza sativa Nutrition 0.000 claims description 4
- 235000009566 rice Nutrition 0.000 claims description 4
- 239000010902 straw Substances 0.000 claims description 4
- 239000003513 alkali Substances 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 230000002087 whitening effect Effects 0.000 abstract description 6
- 239000002537 cosmetic Substances 0.000 abstract description 4
- 239000002932 luster Substances 0.000 abstract description 2
- 229940074410 trehalose Drugs 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 45
- 239000003921 oil Substances 0.000 description 19
- 230000000694 effects Effects 0.000 description 12
- 238000012360 testing method Methods 0.000 description 9
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 6
- 238000000265 homogenisation Methods 0.000 description 6
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- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 5
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- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
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- 239000000047 product Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
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- 239000000203 mixture Substances 0.000 description 3
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- 229940046009 vitamin E Drugs 0.000 description 3
- 241001474374 Blennius Species 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 2
- 239000004909 Moisturizer Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
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- 235000019441 ethanol Nutrition 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 235000020778 linoleic acid Nutrition 0.000 description 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
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- 239000011259 mixed solution Substances 0.000 description 2
- 230000001333 moisturizer Effects 0.000 description 2
- 235000008390 olive oil Nutrition 0.000 description 2
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- 229910052760 oxygen Inorganic materials 0.000 description 2
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- 238000012545 processing Methods 0.000 description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
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- 206010013786 Dry skin Diseases 0.000 description 1
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- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001336 alkenes Chemical group 0.000 description 1
- SOIFLUNRINLCBN-UHFFFAOYSA-N ammonium thiocyanate Chemical compound [NH4+].[S-]C#N SOIFLUNRINLCBN-UHFFFAOYSA-N 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
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- 239000002585 base Substances 0.000 description 1
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- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
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- 229960000541 cetyl alcohol Drugs 0.000 description 1
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- 239000006071 cream Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
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- 239000012153 distilled water Substances 0.000 description 1
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- 239000000686 essence Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
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- 229960005150 glycerol Drugs 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
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- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
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- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 description 1
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- 239000000230 xanthan gum Substances 0.000 description 1
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- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of cosmetics, and particularly discloses nourishing, moisturizing and moisturizing emulsion and a preparation method thereof, wherein the nourishing, moisturizing and moisturizing emulsion mainly comprises glycerol, 1, 2-pentanediol, camellia seed oil, trehalose, squalane and lycopene stable emulsion, wherein the content of the lycopene stable emulsion is 8-12wt%. The nourishing and moisturizing milk provided by the invention is rich in moisturizing and whitening components, can improve the moisture and elasticity of skin, deeply nourish and fine the skin, keep the skin moist and luster, and make the skin tender and smooth.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to nourishing and moisturizing milk and a preparation method thereof.
Background
When the water-oil balance of the skin is broken, the problems of dry skin, water deficiency, dullness and the like can occur. Moisturizing is an indispensable link of daily skin care, and proper skin care products can help to rebuild skin barrier, increase skin moisture, prevent loss of moisture on the skin surface and form a moisturizing film to lock moisture. Common moisturizing skin care products include moisturizing lotions, moisturizing creams, moisturizing essences and the like. Moisturizing emulsion is a common moisturizing skin care product, and generally consists of water, oil, humectant, emulsifier and other components. The emulsifier can mix water and oil together to form emulsion-like texture, so that the moisturizing component can better permeate into the skin surface layer to achieve the effects of moisturizing. The moisturizing component in the moisturizing emulsion can ensure that the skin can better lock moisture, resist the damage of the external environment to the skin and improve the skin state. When the moisturizing lotion is used, a product suitable for skin can be selected, and the moisturizing lotion can be applied to the skin of the whole face and the neck in a massaging way. After the skin is used, the skin can feel moist and comfortable, and can become brighter and healthier. However, most of the existing moisturizing emulsions have single functions, can only achieve the effect of shallow moisturizing, and cannot meet the deep moisturizing requirement of skin.
The Chinese patent CN106667809A discloses a lycopene whitening, moisturizing and anti-aging emulsion, which comprises the following components: lycopene, seaweed extract, rose essential oil, olive oil, glycerol, propylene glycol, xanthan gum, vitamin E, cetyl alcohol and distilled water, and the invention utilizes the characteristic that pure natural raw material lycopene has super oxidation resistance, can effectively remove free radicals, prevent skin cells from being damaged, whiten and prevent sunburn, and delay skin aging; meanwhile, the seaweed extract can deeply moisturize and supplement water and promote skin metabolism, so that the skin care effects of whitening, moisturizing and resisting aging are achieved, but lycopene is insoluble in water and easily loses activity due to oxidization, so that the lycopene is low in bioavailability and unstable in performance when being directly used as a raw material of cosmetics, and cannot well exert the effects of the lycopene.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides the nourishing and moisturizing emulsion, which utilizes the characteristic that the acetylated hemicellulose has amphipathy formed by a hydrophobic chain and a hydrophilic chain by processing pure natural raw material lycopene into lycopene stable emulsion, so that the acetylated hemicellulose is stably adsorbed on an oil-water interface to form a barrier film, thereby protecting lycopene in an oil system from oxidative degradation, and simultaneously improving the biocompatibility of the lycopene and the emulsion stability of the moisturizing emulsion. The invention also provides a preparation method of the nourishing and moisturizing milk, which is simple and convenient to operate.
The technical scheme adopted by the invention is as follows:
A milk for nourishing, caring skin and keeping moisture comprises glycerol, 1, 2-pentanediol, camellia seed oil, trehalose, squalane, and lycopene stable milk.
Lycopene is a purely natural powerful antioxidant active substance, and can be used for whitening skin, resisting skin aging, preventing color spot formation and the like in the field of skin care. The lycopene can help skin to be less than ultraviolet and air radiation pollution, lighten skin oxidative stress and inflammatory reaction, promote regeneration and repair of skin cells, reduce melanin deposition in skin, prevent color spots from forming, play a role in whitening skin, promote blood circulation of skin, improve moisture content and elasticity of skin, and keep skin moist and luster.
Lycopene has some disadvantages during use: on the one hand, lycopene has a conjugated polyunsaturated olefin structure, is sensitive to light and oxygen reactions and is easy to oxidize and lose activity, and on the other hand, lycopene serving as a fat-soluble substance cannot be stably dispersed in water and is easy to damage by acid in a system.
Therefore, the invention adopts homogeneous reaction to prepare the acetyl hemicellulose which is evenly distributed, the introduction of the acetyl ensures that the hemicellulose has excellent hydrophilic/hydrophobic balance, can be well dispersed in water, can be stably adsorbed on an oil-water interface to form a barrier film, protects lycopene in an oil system from oxidative degradation, and improves the biocompatibility of the lycopene and the emulsion stability of emulsion.
Preferably, the content of the lycopene stabilizing milk is 8-12wt%.
Preferably, the preparation method of the lycopene stable milk comprises the following steps:
Adding lycopene into jojoba oil according to a solid-to-liquid ratio of 0.1-0.3kg:50L, performing ultrasonic treatment for 20-30min to obtain an oil system dispersion liquid, adding acetylated hemicellulose into water according to a solid-to-liquid ratio of 0.4-0.6kg:50L, performing ultrasonic treatment for 5-15min to obtain an aqueous dispersion liquid, adding the oil system dispersion liquid into the aqueous dispersion liquid according to a mass ratio of 3:5-10, uniformly mixing, homogenizing under high pressure, and obtaining the lycopene stable emulsion.
It is emphasized that in the process of preparing the lycopene stabilized emulsion, the preferred jojoba oil not only can well dissolve lycopene, but also is easy to absorb, natural and non-irritating, and has the effects of moisturizing and moistening skin.
Preferably, the power of the ultrasonic treatment is 200-300W and the frequency is 20-40kHz.
Preferably, the high-pressure homogenization is carried out at a pressure of 500-1500bar and a cycle number of 3-6.
Preferably, the preparation method of the acetylated hemicellulose comprises the following steps:
adding alkali extracted hemicellulose into dimethyl sulfoxide solution of sodium chloride according to a solid-to-liquid ratio of 1kg:15-20L, mixing uniformly, adjusting pH to neutral, adding acetyl chloride, stirring for reaction, adding absolute ethyl alcohol for precipitation after the reaction is finished, standing, centrifuging to obtain precipitate, washing, and drying to obtain the acetylated hemicellulose.
Hemicellulose is an important component of plant cell walls and is very abundant in nature. The hemicellulose molecule mainly comprises a plurality of types of sugar units, the molecular structure of the hemicellulose molecule contains a large number of carboxyl and hydroxyl functional groups, and simultaneously the hemicellulose molecule also contains acetyl substituent groups under the original state, so that the hemicellulose molecule has amphipathy formed by a hydrophobic chain and a hydrophilic chain. However, the common alkali extraction in industry can lead to easy removal of acetyl substituted base in hemicellulose molecular structure, and seriously damages the amphipathy of natural hemicellulose molecules.
According to the invention, acetyl is uniformly introduced into the molecular structure of alkali-extracted hemicellulose through homogeneous phase reaction, and the obtained acetylated hemicellulose has excellent amphipathy, and can realize high adsorption concentration on an oil-water interface, so that the method has a good barrier effect on an oil system and has a good protection effect on lycopene in the oil system.
Preferably, the concentration of the dimethyl sulfoxide solution of sodium chloride is 0.5-0.8wt%.
Preferably, the amount of the acetyl chloride is 10-15wt% of the mass of the alkali-extracted hemicellulose.
Preferably, the conditions of the stirring reaction are: stirring and reacting for 120-160min at 50-55 ℃ and 100-200 rpm.
Preferably, 2-5 times the volume of absolute ethanol is added.
Preferably, the mixture is allowed to stand for 250 to 300 minutes.
Preferably, the preparation method of the alkali-extracted hemicellulose comprises the following steps:
Crushing rice straw, sieving, adding NaOH aqueous solution, heating and stirring, filtering after finishing, regulating the pH of the filtrate to be neutral, adding absolute ethyl alcohol for precipitation, standing, centrifuging to obtain precipitate, washing and drying to obtain alkali-extracted hemicellulose.
Preferably, the rice straw is crushed and sieved by a 60-100-mesh sieve.
Preferably, the aqueous NaOH solution is added in a solid-to-liquid ratio of 1 kg:15-20L.
Preferably, the concentration of the aqueous NaOH solution is 6-8wt%.
Preferably, the conditions of heating and stirring are: stirring at 90-95deg.C and 100-200rpm for 150-200min.
Preferably, 2-5 times the volume of absolute ethanol is added.
Preferably, the mixture is allowed to stand for 250 to 300 minutes.
Preferably, the nourishing and moisturizing lotion is prepared from the following raw materials:
10-15wt% of glycerol, 1-3wt% of 1, 2-pentanediol, 2-5wt% of camellia seed oil, 1-2wt% of trehalose, 1-3wt% of squalane, 0.03-0.05wt% of p-hydroxyacetophenone, 1.5-2wt% of glyceryl monostearate, 1-1.5wt% of behenyl alcohol, 8-12wt% of lycopene stable milk and the balance of water.
Glycerol, 1, 2-pentanediol and trehalose are used as moisturizers, which can absorb moisture and lock up moisture, and increase skin humidity and softness.
In addition, glycerol and water are used as solvents to enable other active components to be absorbed by skin more easily, 1, 2-pentanediol can also improve the stability of moisturizing milk to a certain extent, inhibit bacterial growth, and trehalose can also enhance the moisture storage capacity of skin cells to enable skin to be moisturized.
The camellia seed oil is rich in vitamin E and unsaturated fatty acid, is favorable for keeping moisture and elasticity of skin, and the squalane can strengthen the skin barrier function and prevent moisture loss and external irritants from entering the skin.
The raw materials cooperate with each other in the moisturizing emulsion to exert better moisturizing, nourishing and moisturizing effects, so that the skin is comprehensively cared.
The p-hydroxyacetophenone used as preservative and antioxidant can prevent deterioration and oxidation of moisturizing milk, and maintain its stability. Glyceryl monostearate and behenyl alcohol are emulsifiers and thickeners that assist in forming a stable emulsion while increasing the consistency and comfort of the moisturizing emulsion.
The invention also provides a preparation method of the nourishing and moisturizing milk.
Preferably, the preparation method of the nourishing and moisturizing milk comprises the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 70-80deg.C and 300-600rpm for 20-40min, adding trehalose, p-hydroxyacetophenone and water, stirring for 10-20min, cooling to 40-50deg.C, adding lycopene stable emulsion, stirring for 10-30min, naturally cooling to room temperature, and bottling.
The invention has the beneficial effects that: the nourishing and moisturizing milk prepared by the invention is rich in moisturizing and whitening components, can deeply moisturize and moisturize, improve the moisture and elasticity of skin, and make the skin tender and smooth. According to the invention, the lycopene in an oil system is protected from oxidative degradation by processing the pure natural raw material lycopene into the lycopene stable emulsion, and meanwhile, the biocompatibility of the lycopene and the emulsion stability of the moisturizing emulsion are improved; in addition, glycerol, 1, 2-pentanediol and trehalose are used as moisturizers, so that the moisturizing agent can absorb moisture and lock the moisture, and the moisture and softness of skin are improved; the camellia seed oil is rich in vitamin E and unsaturated fatty acid, is beneficial to keeping moisture and elasticity of skin, and squalane can enhance the skin barrier function and prevent moisture loss and external irritants from entering the skin; the raw materials are mutually cooperated in the moisturizing milk, so that the skin is comprehensively cared.
Detailed Description
The above summary of the present invention is described in further detail below in conjunction with the detailed description, but it should not be understood that the scope of the above-described subject matter of the present invention is limited to the following examples.
The preparation method of the alkali-extracted hemicellulose in the embodiment comprises the following steps: crushing rice straw, sieving with a 80-mesh sieve, adding 7.5wt% NaOH aqueous solution according to a solid-to-liquid ratio of 1kg:18L, stirring for 180min at 93 ℃ and 150rpm, filtering after the completion, regulating the pH of the filtrate to be neutral, adding 2.5 times of volume of absolute ethyl alcohol for precipitation, standing for 270min, centrifuging to obtain precipitate, washing and drying to obtain alkali-extracted hemicellulose.
Example 1
A nourishing and moisturizing lotion is prepared from the following raw materials:
13wt% of glycerol, 2wt% of 1, 2-pentanediol, 3wt% of camellia seed oil, 1.5wt% of trehalose, 2.5wt% of squalane, 0.04wt% of p-hydroxyacetophenone, 1.8wt% of glycerol monostearate, 1.2wt% of behenyl alcohol, 10wt% of lycopene stable milk and the balance of water.
The preparation method of the lycopene stable milk comprises the following steps:
Adding lycopene into jojoba oil according to a solid-to-liquid ratio of 0.18kg:50L, performing ultrasonic treatment for 25min to obtain an oil system dispersion liquid, adding acetylated hemicellulose into water according to a solid-to-liquid ratio of 0.52kg:50L, performing ultrasonic treatment for 10min to obtain an aqueous dispersion liquid, adding the oil system dispersion liquid into the aqueous dispersion liquid according to a mass ratio of 3:7, uniformly mixing, and homogenizing under high pressure to obtain the lycopene stable emulsion. Wherein, the power of ultrasonic treatment is 250W, and the frequency is 30kHz; the high-pressure homogenization pressure was 1000bar and the number of cycles was 5.
The preparation method of the acetylated hemicellulose comprises the following steps:
Adding alkali-extracted hemicellulose into dimethyl sulfoxide solution of 0.7wt% sodium chloride according to a solid-to-liquid ratio of 1kg:18L, mixing uniformly, adjusting pH to be neutral, adding acetyl chloride, stirring for 150min at 52 ℃ and 150rpm, adding absolute ethyl alcohol with the volume of 2.5 times of that of the alkali-extracted hemicellulose for precipitation after the completion of the stirring, centrifuging after standing for 270min, taking the precipitate, washing and drying to obtain the acetylated hemicellulose.
A nourishing and moisturizing lotion is prepared by the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 75deg.C and 500rpm for 30min, adding trehalose, p-hydroxyacetophenone and water, stirring for 15min, cooling to 45deg.C, adding lycopene stable emulsion, stirring for 20min, naturally cooling to room temperature, and bottling.
Example 2
A nourishing and moisturizing lotion is prepared from the following raw materials:
13wt% of glycerol, 2wt% of 1, 2-pentanediol, 3wt% of camellia seed oil, 1.5wt% of trehalose, 2.5wt% of squalane, 0.04wt% of p-hydroxyacetophenone, 1.8wt% of glycerol monostearate, 1.2wt% of behenyl alcohol, 10wt% of lycopene homogeneous emulsion and the balance of water.
The preparation method of the lycopene homogeneous emulsion comprises the following steps:
Adding lycopene into jojoba oil according to a solid-to-liquid ratio of 0.18kg:50L, performing ultrasonic treatment for 25min to obtain an oil system dispersion liquid, adding the oil system dispersion liquid into water according to a mass ratio of 3:7, uniformly mixing, and homogenizing under high pressure to obtain the lycopene homogenized emulsion. Wherein, the power of ultrasonic treatment is 250W, and the frequency is 30kHz; the high-pressure homogenization pressure was 1000bar and the number of cycles was 5.
A nourishing and moisturizing lotion is prepared by the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 75deg.C and 500rpm for 30min, adding trehalose, p-hydroxyacetophenone and water, stirring for 15min, cooling to 45deg.C, adding lycopene homogeneous emulsion, stirring for 20min, naturally cooling to room temperature, and bottling.
Example 3
A nourishing and moisturizing lotion is prepared from the following raw materials:
13wt% of glycerol, 2wt% of 1, 2-pentanediol, 3wt% of camellia seed oil, 1.5wt% of trehalose, 2.5wt% of squalane, 0.04wt% of p-hydroxyacetophenone, 1.8wt% of glycerol monostearate, 1.2wt% of behenyl alcohol, 10wt% of lycopene stable milk and the balance of water.
The preparation method of the lycopene stable milk comprises the following steps:
Adding lycopene into jojoba oil according to a solid-to-liquid ratio of 0.18kg:50L, performing ultrasonic treatment for 25min to obtain an oil system dispersion liquid, adding alkali-extracted hemicellulose into water according to a solid-to-liquid ratio of 0.52kg:50L, performing ultrasonic treatment for 10min to obtain an aqueous dispersion liquid, adding the oil system dispersion liquid into the aqueous dispersion liquid according to a mass ratio of 3:7, uniformly mixing, and homogenizing under high pressure to obtain the lycopene stable emulsion. Wherein, the power of ultrasonic treatment is 250W, and the frequency is 30kHz; the high-pressure homogenization pressure was 1000bar and the number of cycles was 5.
A nourishing and moisturizing lotion is prepared by the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 75deg.C and 500rpm for 30min, adding trehalose, p-hydroxyacetophenone and water, stirring for 15min, cooling to 45deg.C, adding lycopene stable emulsion, stirring for 20min, naturally cooling to room temperature, and bottling.
Example 4
A nourishing and moisturizing lotion is prepared from the following raw materials:
13wt% of glycerol, 2wt% of 1, 2-pentanediol, 3wt% of camellia seed oil, 1.5wt% of trehalose, 2.5wt% of squalane, 0.04wt% of p-hydroxyacetophenone, 1.8wt% of glycerol monostearate, 1.2wt% of behenyl alcohol, 10wt% of homogeneous emulsion and the balance of water.
The preparation method of the homogenized milk comprises the following steps:
Adding jojoba oil into water according to a mass ratio of 3:7, uniformly mixing, and homogenizing under high pressure to obtain the homogenized milk. Wherein, the pressure of high-pressure homogenization is 1000bar, and the cycle number is 5.
A nourishing and moisturizing lotion is prepared by the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 75deg.C and 500rpm for 30min, adding trehalose, p-hydroxyacetophenone and water, stirring for 15min, cooling to 45deg.C, adding homogenized milk, stirring for 20min, naturally cooling to room temperature, and bottling.
Example 5
A nourishing and moisturizing lotion is prepared from the following raw materials:
13wt% of glycerol, 2wt% of 1, 2-pentanediol, 3wt% of camellia seed oil, 1.5wt% of trehalose, 2.5wt% of squalane, 0.04wt% of p-hydroxyacetophenone, 1.8wt% of glycerol monostearate, 1.2wt% of behenyl alcohol, 10wt% of lycopene stable milk and the balance of water.
The preparation method of the lycopene stable milk comprises the following steps:
Adding lycopene into olive oil according to a solid-to-liquid ratio of 0.18kg:50L, performing ultrasonic treatment for 25min to obtain an oil system dispersion liquid, adding acetylated hemicellulose into water according to a solid-to-liquid ratio of 0.52kg:50L, performing ultrasonic treatment for 10min to obtain an aqueous dispersion liquid, adding the oil system dispersion liquid into the aqueous dispersion liquid according to a mass ratio of 3:7, uniformly mixing, and homogenizing under high pressure to obtain the lycopene stable emulsion. Wherein, the power of ultrasonic treatment is 250W, and the frequency is 30kHz; the high-pressure homogenization pressure was 1000bar and the number of cycles was 5.
The preparation method of the acetylated hemicellulose comprises the following steps:
Adding alkali-extracted hemicellulose into dimethyl sulfoxide solution of 0.7wt% sodium chloride according to a solid-to-liquid ratio of 1kg:18L, mixing uniformly, adjusting pH to be neutral, adding acetyl chloride, stirring for 150min at 52 ℃ and 150rpm, adding absolute ethyl alcohol with the volume of 2.5 times of that of the alkali-extracted hemicellulose for precipitation after the completion of the stirring, centrifuging after standing for 270min, taking the precipitate, washing and drying to obtain the acetylated hemicellulose.
A nourishing and moisturizing lotion is prepared by the following steps:
Mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate and behenyl alcohol with glycerol, stirring at 75deg.C and 500rpm for 30min, adding trehalose, p-hydroxyacetophenone and water, stirring for 15min, cooling to 45deg.C, adding lycopene stable emulsion, stirring for 20min, naturally cooling to room temperature, and bottling.
Test example 1
Moisture retention capability test: volunteers were randomly divided into 5 groups of 20 people each, each half of men and women, between ages 20-40. The nourishing and moisturizing milk prepared above was used for the test period 2 times daily for 3 weeks without using other cosmetics. Moisture content of the stratum corneum was measured before and after 3 weeks of use using a skin moisture tester moisture test probe Corneometer CM 825.
TABLE 1 results of moisture retention test
Test example 2
Antioxidant Capacity test: 1mL of the nourishing and moisturizing milk prepared in the above example (stored at room temperature for 3 weeks) was weighed and placed in a test tube, 5mL of PBS buffer (0.05 mol/L, pH =7.0) and 5mL of linoleic acid solution (50 mmol/L, 95wt% ethanol aqueous solution as solvent) were added and mixed uniformly, and finally 2.5mL of water was added and mixed uniformly, and the obtained mixed solution was placed in a biochemical incubator (50 ℃) for 2 days to determine the oxidation degree of linoleic acid. 0.2mL of the oxidized mixed solution is taken, 0.2mL of ammonium thiocyanate aqueous solution (30 wt%), 9.4mL of ethanol aqueous solution (75 wt%) and 0.2mL of ferrous chloride solution (20 mol/L, 3.5wt% hydrochloric acid as solvent) are sequentially added for oscillation reaction for 3min, and the absorbance at 500nm is measured after the completion. Wherein, lipid oxidation inhibition ratio% = [1- (a 1-A0)/(A' 1-A' 0)]×100,A' 0 and a ' 1) is absorbance before and after oxidation after adding the nourishing, moisturizing and moisturizing milk of the above examples, a 0 and a 1 are absorbance before and after oxidation, respectively, of a blank without adding the nourishing, moisturizing and moisturizing milk of the above examples.
TABLE 2 results of antioxidant capacity test
| Lipid oxidation inhibition rate% | |
| Example 1 | 89.08 |
| Example 2 | 68.39 |
| Example 3 | 75.62 |
| Example 5 | 87.97 |
Lycopene is used as a powerful antioxidant active substance, and has effects of resisting skin aging, relieving skin oxidative stress, reducing skin melanin deposition, and improving skin moisture content and elasticity. However, lycopene is sensitive to light and oxygen, is easily oxidized and loses activity, and cannot be stably dispersed in water, and in the embodiment 1, lycopene is processed into lycopene stable emulsion, and the characteristic that acetylated hemicellulose has amphipathy formed by a hydrophobic chain and a hydrophilic chain is utilized to enable the lycopene to be stably adsorbed on an oil-water interface to form a barrier film so as to protect the lycopene in an oil system from being oxidized and inactivated, and meanwhile, the emulsion stability of the moisturizing emulsion, the biocompatibility and the absorption and utilization effects of the lycopene are improved.
The foregoing describes in detail preferred embodiments of the present invention. It should be understood that numerous modifications and variations can be made in accordance with the concepts of the invention by one of ordinary skill in the art without undue burden. Therefore, all technical solutions which can be obtained by logic analysis, reasoning or limited experiments based on the prior art by the person skilled in the art according to the inventive concept shall be within the scope of protection defined by the claims.
Claims (2)
1. The nourishing and moisturizing lotion is characterized by comprising the following raw materials: 10-15wt% of glycerol, 1-3wt% of 1, 2-pentanediol, 2-5wt% of camellia seed oil, 1-2wt% of trehalose, 1-3wt% of squalane, 0.03-0.05wt% of p-hydroxyacetophenone, 1.5-2wt% of glycerol monostearate, 1-1.5wt% of behenyl alcohol, 8-12wt% of lycopene stable milk and the balance of water;
The preparation method of the lycopene stable milk comprises the following steps:
Adding lycopene into jojoba oil according to a solid-to-liquid ratio of 0.1-0.3kg:50L, performing ultrasonic treatment for 20-30min to obtain an oil system dispersion liquid, adding acetylated hemicellulose into water according to a solid-to-liquid ratio of 0.4-0.6kg:50L, performing ultrasonic treatment for 5-15min to obtain an aqueous dispersion liquid, adding the oil system dispersion liquid into the aqueous dispersion liquid according to a mass ratio of 3:5-10, uniformly mixing, homogenizing under high pressure, and obtaining the lycopene stable emulsion;
The preparation method of the acetylated hemicellulose comprises the following steps: adding alkali extracted hemicellulose into dimethyl sulfoxide solution of sodium chloride according to a solid-to-liquid ratio of 1kg:15-20L, mixing uniformly, adjusting pH to neutral, adding acetyl chloride, stirring for reaction, adding absolute ethyl alcohol for precipitation after the reaction is finished, standing, centrifuging to obtain precipitate, washing, and drying to obtain acetylated hemicellulose;
The preparation method of the alkali-extracted hemicellulose comprises the following steps: crushing rice straw, sieving with a 80-mesh sieve, adding 7.5wt% NaOH aqueous solution according to a solid-to-liquid ratio of 1kg:18L, stirring for 180min at 93 ℃ and 150rpm, filtering after the completion, regulating the pH of the filtrate to be neutral, adding 2.5 times of volume of absolute ethyl alcohol for precipitation, standing for 270min, centrifuging to obtain precipitate, washing and drying to obtain alkali-extracted hemicellulose.
2. The method for preparing the nourishing and moisturizing milk according to claim 1, comprising the following steps: mixing 1, 2-pentanediol, camellia seed oil, squalane, glyceryl monostearate, and behenyl alcohol with glycerol, stirring, adding trehalose, p-hydroxyacetophenone and water, stirring, adding lycopene stable emulsion, stirring, cooling, and bottling to obtain the nourishing, moisturizing emulsion.
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| CN101182361A (en) * | 2007-12-07 | 2008-05-21 | 华南理工大学 | Method for preparing acetylated hemicellulose by employing catalysis of iodine |
| CN105853245A (en) * | 2016-04-29 | 2016-08-17 | 佛山市芊茹化妆品有限公司 | Anti-aging composition containing lycopene and microcapsule and preparation method thereof |
| CN112545957A (en) * | 2020-12-18 | 2021-03-26 | 现代百朗德生物科技(江苏)有限公司 | Essence milk with effects of moisturizing and removing red blood streak and preparation method thereof |
| CN114569507A (en) * | 2022-03-14 | 2022-06-03 | 王平 | Moisturizing emulsion and preparation method thereof |
| CN115414302A (en) * | 2022-11-04 | 2022-12-02 | 广州市高姿化妆品有限公司 | Skin-moistening and nourishing type moisturizing emulsion and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL146737A (en) * | 2001-11-26 | 2010-02-17 | Lycored Natural Prod Ind Ltd | Method for protecting lycopene dispersed in tomato fibers |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101182361A (en) * | 2007-12-07 | 2008-05-21 | 华南理工大学 | Method for preparing acetylated hemicellulose by employing catalysis of iodine |
| CN105853245A (en) * | 2016-04-29 | 2016-08-17 | 佛山市芊茹化妆品有限公司 | Anti-aging composition containing lycopene and microcapsule and preparation method thereof |
| CN112545957A (en) * | 2020-12-18 | 2021-03-26 | 现代百朗德生物科技(江苏)有限公司 | Essence milk with effects of moisturizing and removing red blood streak and preparation method thereof |
| CN114569507A (en) * | 2022-03-14 | 2022-06-03 | 王平 | Moisturizing emulsion and preparation method thereof |
| CN115414302A (en) * | 2022-11-04 | 2022-12-02 | 广州市高姿化妆品有限公司 | Skin-moistening and nourishing type moisturizing emulsion and preparation method thereof |
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