CN111450003A - Anti-aging and beautifying nutrient containing golden fragrant willow extract, preparation method thereof, essence and extraction method of golden fragrant willow extract - Google Patents
Anti-aging and beautifying nutrient containing golden fragrant willow extract, preparation method thereof, essence and extraction method of golden fragrant willow extract Download PDFInfo
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- CN111450003A CN111450003A CN202010318110.8A CN202010318110A CN111450003A CN 111450003 A CN111450003 A CN 111450003A CN 202010318110 A CN202010318110 A CN 202010318110A CN 111450003 A CN111450003 A CN 111450003A
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Abstract
The invention discloses an anti-aging and face-brightening nutrient containing a golden willow extract, which comprises the following components in parts by weight: 1-10 parts of polyol; 1-10 parts of a humectant; 2-20 parts of an emollient; 1-5 parts of an emulsifier; 0.1-2 parts of a thickening agent; 0.1-2 parts of a pH regulator; 0.1-5 parts of an antioxidant; 0.1-10 parts of a skin conditioner; 80-100 parts of deionized water; the skin conditioner contains extract of Salix psammophila. The invention effectively prevents skin photoaging, restores the balance of melanocytes, restores the natural color and luster of skin, obviously reduces wrinkles and increases skin elasticity by adding the salix psammophila extract into various auxiliary agents.
Description
Technical Field
The invention relates to the technical field of skin care products, in particular to an anti-aging and beautifying nutrient containing a golden fragrant willow extract, a preparation method thereof, essence and an extraction method of the golden fragrant willow extract.
Background
With the continuous improvement of living standard, the requirements of people on the quality of life, especially the facial appearance, are higher and higher. With the change of environment and the increase of age, the influence of various pressures of ultraviolet rays, work, life and the like, more and more skin problems occur in succession, such as the generation of melanin, dark yellow skin, facial blemishes, skin photoaging, dry and thin skin epidermal tissues, weakened skin elasticity and the like, and the various problems of skin improvement are caused by the fact that common toner, emulsion and cream are difficult to penetrate through a skin barrier to enter a dermis layer, so essence is needed to supplement nutrition and moisture needed by the skin, strengthen the natural resistance of the skin, stimulate and accelerate the repair and renewal of cells, drive skin metabolism, make the skin brighter and firmer and protect the skin most comprehensively.
Although the essence product with the effects of resisting wrinkles, whitening skin and the like is declared on the market to be full of eyes, the effect is poor, the skin aging cannot be effectively resisted, the skin color can be brightened, the skin problem cannot be comprehensively solved, the preparation method of the essence is complex, and especially, the extraction process of some plants added into the essence is complex, the extraction rate is low, and the cost is high.
Therefore, the inventors have endeavored to design a nutrient for resisting premature aging and brightening the face, a preparation method thereof and an extraction method of essence and extract so as to solve the problems.
Disclosure of Invention
In order to overcome the disadvantages and shortcomings of the prior art, one object of the present invention is to: the anti-aging and skin-brightening nutrient containing the salix psammophila extract is provided, and the salix psammophila extract is added into various auxiliary agents, so that the skin photoaging is effectively prevented, the balance of melanocytes is restored, the natural color and luster of the skin are restored, wrinkles are obviously reduced, and the skin elasticity is increased.
In order to overcome the disadvantages and shortcomings of the prior art, another object of the present invention is to: the preparation method of the anti-aging and beautifying nutrient containing the golden fragrant willow extract is provided, the nutrient is quickly prepared by homogenizing and emulsifying an oil phase and a water phase and matching with other auxiliary agents, and the preparation cost of the nutrient is reduced.
To overcome the disadvantages and shortcomings of the prior art, it is a further object of the present invention to: provides an essence containing the extract of the salix integra, which is used as a transdermal administration tool and a transdermal administration tool through a hyper-deformable vesicle, and the nutrient containing the extract of the salix integra is introduced into the deep layer of living cells of the skin, so that the speed of absorbing the nutrient by the skin is accelerated.
To overcome the disadvantages and shortcomings of the prior art, it is a further object of the present invention to: the extraction method of the golden fragrant willow extract is provided, and the extraction rate of the golden fragrant willow is improved by low-temperature extraction, concentration and redispersion.
One purpose of the invention is realized by the following technical scheme:
the anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The salix psammophila (with the scientific name of Melaleuca brachacta) is excellent color-leaf tree species, soft golden-yellow branches have strong typhoon resistance, water logging resistance and salt and alkali resistance, and the salix psammophila is particularly suitable for urban landscaping in coastal areas, one of new species of colored-leaf trees which are most popular in the world at present and have the best visual effect, and because the salix psammophila essential oil mainly comprises methyl eugenol (with the content of 92.185%), methyl cinnamate contains the second methyl cinnamate (with the content of 3.795%) and the rest is less than 0.4%, the methyl eugenol has good antibacterial and insecticidal activity, and the salix psammophila is rich in natural polyphenols and flavonoids substances, has strong antioxidant effect and whitening effect, has an inhibiting effect on skin melanin, can effectively resist skin aging, and has strong acaricidal activity and antiseptic function.
As an improvement of the anti-aging and beautifying nutrient containing the golden fragrant willow extract, the mass of the golden fragrant willow extract accounts for 10-30% of the total mass of the skin conditioner.
As an improvement of the anti-premature lightening nutrition of the present invention containing the extract of salix integra, the skin conditioner is used for improving pigmentation, spots, fine lines, acne, sebum rawhide and barrier repair, promoting collagen synthesis, and reducing inflammatory cytokine production, and the skin conditioner further comprises at least one of niacinamide, glycolipid, oat kernel oil, cedar bud extract, phytosterol/octyldodecanol lauroyl glutamate, split yeast fermentation product lysate, umbilical cord extract, placental protein, and placental enzyme.
The oat kernel oil, the cedar bud extract and the phytosterol/octyldodecanol lauroyl glutamate are natural plants, belong to natural renewable raw materials, and have good moistening and skin-care effects. Wherein the oat kernel oil and the cedar bud extract are certified by ECOCERT of France.
The golden willow extract-containing nutrient for resisting premature senility and brightening the face is improved by comprising 0.5-1 part of preservative in parts by weight;
the polyalcohol is at least one of aminomethyl propanol, butanediol, dipropylene glycol and glycerol, and can soften stratum corneum by matching with polyalcohol, protect skin barrier, and moisturize skin barrier.
The humectant is at least one of sodium hyaluronate, dextran, Bolinate Spirulina extract, panthenol, erythritol and trehalose;
moisturizers are hydrophilic skin moisturizing substances that have the ability to bind water in the lower humidity range, moisturize the skin, and they can help maintain the skin in a more than normal equilibrium moisture content by controlling the exchange of moisture between the product and the surrounding air, and thus, reduce skin dryness.
The emollient is at least one of shea butter, octyl dodecanol, polyhydroxystearic acid, octyl dodecanol myristate, isononyl isononanoate, argania spinosa kernel oil, squalane and oat kernel oil;
emollients are cosmetic ingredients that help maintain the soft, pliable, smooth appearance of skin. The function of emollients is to remain on the skin surface and to provide lubrication within the stratum corneum. Generally, the skin fills the spaces in the skin surface, replacing the lipid lost in the stratum corneum, reducing the scaly skin, and improving the appearance of the skin.
The emulsifier is at least one of polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax, cetyl alcohol, triglyceride C10-18 fatty acid, polyhydroxystearic acid, candelilla wax, stearyl behenate, cetyl stearate, stearyl stearate and behenic acid;
emulsifiers are surface-active substances which have both hydrophilic and lipophilic groups in the molecule and which accumulate at the oil/water interface and reduce the interfacial tension and the energy required to form an emulsion, thus increasing the energy of the emulsion and improving the surface tension between the various constituent phases of the emulsion to form a homogeneous and stable dispersion or emulsion.
The thickening agent is at least one of carbomer, acacia gum and xanthan gum;
the thickening agent is mainly used for improving and increasing the viscosity of the product, keeping the stability of the product and improving the physical properties of the product.
The pH regulator is used for adjusting or maintaining the pH value to enable the pH value of the nutrient to be 4.0-8.5, and the pH regulator is at least one of triethanolamine, arginine, citric acid and sodium citrate;
the antioxidant is used for protecting skin from oxidative damage and helping the body self antioxidant system to remove excessive free radicals so as to maintain the balance of oxidation and antioxidation, and the antioxidant is at least one of mulberry extract, superoxide dismutase, tocopherol acetate, Daphnia hirsuta fruit oil, vitamin C and anthocyanin which wrap the oxidized resveratrol;
the preservative is used for delaying the putrefaction caused by the growth or chemical change of microorganism, and the preservative is at least one of ethylhexyl glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, 1, 2-pentanediol, glyceryl caprylate and caprylyl hydroximic acid.
The other purpose of the invention is realized by the following technical scheme: a method for preparing an anti-aging and skin-brightening nutrient containing a golden willow extract comprises the following steps:
and 4, sequentially adding an antioxidant and a skin conditioner into the main pot, uniformly stirring, and cooling to room temperature to form the nutrient.
The other purpose of the invention is realized by the following technical scheme: the essence containing the golden fragrant willow extract comprises a nutrient and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1:1 to 10 percent of the raw materials.
In order to make the skin care product really effective, like medicines or cosmeceuticals, the nutrients of the essence must reach the deep layer where the living cells of the skin are located to exert the efficacy of the skin care product, so the vesicle is used as a transmission tool for transdermal administration and percutaneous administration, and the nutrients can quickly reach the deep layer of the skin.
As an improvement of the essence of the invention, the emulsion comprises at least one of 6-functional polyglycerol ester, 10-functional polyglycerol ester, sorbitan ester, dicetyl phosphate, magnolol/honokiol and mulberry extract.
Wherein, 6 functional group polyglycerol esters and 10 functional group polyglycerol esters are formed into bilayers by using glycerol and natural oil through a chemical synthesis method, and the 6 functional group polyglycerol esters are at least one of sunflower seed oil polyglycerol-6 esters, wild almond oil polyglycerol-6 esters and hazelnut oil polyglycerol-6 esters; the 10-functional polyglycerol ester is at least one of polyglycerol-10 palmitate (coconut oil), polyglycerol-10 laurate (coconut oil) and polyglycerol-10 oleate (olive oil); magnolol/honokiol refers to a mixture of magnolol and honokiol, and the stability, shape, size and other properties of the bilayer can be adjusted by adjusting the ratio of the magnolol to the honokiol.
The sorbitan esters are at least one of sorbitan palmitate and sorbitan oleate, are used for forming bilayers of deformed vesicles, and can also influence membrane permeability, encapsulation efficiency and rigidity of the bilayers;
dicetyl phosphate not only forms bilayers, but also enhances stability.
Mulberry extract is used for embedding in vesicle to prevent air contact.
As an improvement of the essence, the vesicle diameter of the emulsion is 150-250 nm, the center of the vesicle is composed of an aqueous phase cavity, and one or more bilayers composed of amphiphilic molecules are arranged around the vesicle.
In the invention, hydrophilic drugs (mulberry extract of oxyresveratrol, nicotinamide, schizosaccharomyces cerevisiae fermentation product lysate, umbilical cord extract, placental protein and placental enzyme) can be encapsulated in a water-phase cavity, lipophilic drugs (phytosterol/octyldodecanol lauroyl glutamate) can be combined with a bilayer, the most important factor for percutaneous absorption of the vesicle is elasticity, in the deformed vesicle, the bilayer contains no phospholipids at all and only contains a single-chain surfactant, and has maximum elasticity/deformability, so that the vesicle has maximum transdermal capacity, and can extrude pores in the stratum corneum (the pores in the stratum corneum are directly 20nm and are smaller than one tenth of the diameter of the vesicle) to enter the deep layer of the skin.
The invention also aims to realize the following technical scheme: a method for extracting golden fragrant willow extract comprises the following steps:
(1) picking 1-2 kg of golden fragrant willow leaves, washing, and then soaking in 1000-2000 ml of ethanol with the volume fraction of 95% for 70-72H to dissolve the effective components of the golden fragrant willow from the ethanol;
(2) extracting at the low temperature of 2-4 ℃ to prepare an extracting solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution into 800-1000 ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
In the prior art, the extraction rate of the golden fragrant willow is low, if the golden fragrant willow is extracted by a steam distillation method, the highest extraction rate of obtained golden fragrant willow leaf essential oil is 2.645%, the highest extraction rate of the organic solvent extraction method is 4.51% (leaf beauty, 2014), and the cost of the golden fragrant willow is high due to the low extraction rate of the golden fragrant willow, 95% of ethanol is adopted to dissolve effective components of the golden fragrant willow, and the golden fragrant willow extract is prepared after extraction, concentration and dispersion, wherein the extraction rate of the golden fragrant willow extract is 5% -8% and is higher than that of the golden fragrant willow in the prior art.
As an improvement of the extraction method of the golden fragrant willow extract, the step (2) is specifically as follows: extracting for the first time for 3-4H at the low temperature of 2-4 ℃, filtering, extracting for the second time for 3-4H at the low temperature of 2-4 ℃, and mixing the two extracted liquids to prepare the extracting solution.
The anti-aging and brightening nutrient containing the salix jinguiensis extract has the technical effects that a polyglycerol ester emulsification system is selected, α crystal gel phase is generated in water, in an O/W emulsifier, α gel phase forms a 'gel network' in a continuous water phase, and an apparent layered bilayer binds water to stabilize the gel network, so that the system has viscoelasticity and excellent skin feel, meanwhile, the polyglycerol ester does not stimulate the skin and does not cause the denaturation of skin protein, the prerequisite condition of sensitive skin is that the skin barrier function is reduced, so that the formula selects active ingredients such as phytosterol/octyldodecanol lauroyl glutamate, glycolipid, nicotinamide and the like, the skin barrier function is repaired in advance, and meanwhile, a super vesicle technology is adopted, so that the active ingredients which are difficult to absorb can be efficiently exerted through a DDS (direct digital synthesis) transmission system, and the effects of the nutrient are effectively exerted through the matching of the nicotinamide, the salix jinguiensis extract, the schizolysis yeast, placental protein and the placental enzyme, so that free radicals are captured, ultraviolet immunosuppression is prevented, the anti-inflammatory effect is realized, the loss of reducing the moisture loss of the placenta, the pigmentation, the wrinkles.
The preparation method of the anti-aging and face-brightening nutrient containing the golden willow extract has the following technical effects: the active ingredients are added after emulsification, and are used for protecting the active ingredients from inactivation due to overhigh temperature when the temperature is reduced to below 50 ℃, and simultaneously, the hydrophilicity of the active ingredients after emulsification enables the active ingredients to be well dispersed in an emulsion.
The essence of the invention has the following technical effects: by adopting the super vesicle technology, the active ingredients which are not easy to absorb can be efficiently exerted through a DDS transmission system, the nutrients containing the salix psammophila extract are quickly introduced into the deep layer of living cells of the skin, the speed of absorbing the nutrients by the skin is accelerated, the balance of melanocytes is restored, and the natural color and luster of the skin are restored. The skin care product can effectively capture free radicals, prevent skin photoaging, obviously reduce wrinkles, increase skin elasticity, increase skin barrier and reduce water loss, and has no stimulation to skin.
Compared with the prior art, the extraction method of the golden fragrant willow extract sequentially comprises the steps of low-temperature extraction with ethanol, concentration and butanediol dispersion, the extraction rate of the golden fragrant willow is increased to 5% -8% and is higher than that of the golden fragrant willow in the prior art (the highest extraction rate of the golden fragrant willow in the prior art is 4.51%), the extraction cost of the golden fragrant willow is reduced, and the cost of nutrients and essence is further reduced.
Drawings
FIG. 1a is a comparison graph of the results of a 3-day periocular skin test in a test for lightening periocular fine lines according to the present invention;
FIG. 1b is a comparison graph of the results of the skin test around the eyes for 7 days in the test for lightening the fine lines around the eyes of the present invention;
FIG. 2a is a graph comparing the skin test results of the present invention for 3 days in a smooth skin, pore shrinking test;
FIG. 2b is a graph comparing the skin test results of the present invention for 7 days in a smooth skin, pore shrinking test;
FIG. 3a is a graph comparing the soothing effect of pox inflammation after 3 days of use in the anti-inflammatory soothing skin test of the present invention;
FIG. 3b is a graph comparing the soothing effect of pox inflammation after 7 days of use in the anti-inflammatory soothing skin test of the present invention;
FIG. 4 is a comparison graph of the acne mark lightening effect after 7 days of use in the skin color lightening and acne mark lightening test according to the invention;
FIG. 5a is a graph showing the change of water content in superficial layers of epidermis after half an hour of use in the instant water supplement and long-acting water lock test of the present invention;
FIG. 5b is a graph showing the change in the water loss rate of epidermis after 3 days of use in the instant water supplement, long-acting water lock test of the present invention;
FIG. 5c is a graph showing the change in water content in the deep layer of epidermis after 7 days of use in the instant water supplement and long-acting water lock test of the present invention;
FIG. 6a is a graph showing the change in canthus elasticity after half an hour of use in the instant tightening, long-acting skin elasticity improvement test of the present invention;
FIG. 6b is a graph showing the change in canthus elasticity after 7 days of use in the test of instant tightening and long-acting skin elasticity improvement of the present invention.
Detailed Description
The following embodiments of the present invention will be specifically explained with reference to the examples and the accompanying drawings, which are only used for reference and illustration and do not limit the scope of the invention.
Example 1
The anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The mass of the golden fragrant willow extract accounts for 10% of the total mass of the skin conditioner.
Wherein the skin conditioner further comprises a mixture of nicotinamide, glycolipid, oat kernel oil and cedar bud extract, and the mass ratio of the nicotinamide, the glycolipid, the oat kernel oil and the cedar bud extract is 4:2:1: 1.
The polyalcohol is butanediol;
the humectant is a mixture of sodium hyaluronate and dextran, and the mass ratio of the sodium hyaluronate to the dextran is 1: 20;
the emollient is a mixture of shea butter, octyl dodecanol and polyhydroxystearic acid, and the mass ratio of the shea butter, the octyl dodecanol and the polyhydroxystearic acid is 1:1: 1;
the emulsifier is a mixture of polyglycerol-6 distearate, jojoba esters and polyglycerol-3 beeswax, and the mass ratio of the polyglycerol-6 distearate to the jojoba esters to the polyglycerol-3 beeswax is 1:2: 1;
the thickening agent is carbomer;
the pH regulator is triethanolamine or arginine;
the antioxidant is a mulberry extract and superoxide dismutase wrapping oxyresveratrol, and the mass ratio of the mulberry extract to the superoxide dismutase is 1: 1;
the preservative is a mixture of ethylhexyl glycerol and p-hydroxyacetophenone, and the mass ratio of the ethylhexyl glycerol to the p-hydroxyacetophenone is 1: 3.
The anti-aging and face-brightening nutrient containing the golden willow extract is prepared by the following method, and the preparation method comprises the following steps:
and 4, adding an antioxidant, a skin conditioner and a preservative into the main pot in sequence, stirring uniformly, and cooling to room temperature to form the nutrient.
The essence containing the golden fragrant willow extract comprises the nutrient containing the golden fragrant willow extract and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1:1 percent of the components are mixed.
Wherein the emulsion comprises 6 functional polyglycerol esters and 10 functional polyglycerol esters, the mass ratio of the 6 functional polyglycerol esters to the 10 functional polyglycerol esters is 1:3, the diameter of the vesicle of the emulsion is 150nm,
the extraction method of the golden fragrant willow extract comprises the following steps:
(1) picking 1kg of golden willow leaves, cleaning, and soaking in 1000ml of ethanol with the volume fraction of 95% for 70H;
(2) extracting 3H for the first time at the low temperature of 2 ℃, filtering, extracting 3H for the second time at the low temperature of 2 ℃, and mixing the liquid extracted for the second time to prepare an extracting solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution in 800ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
Example 2
The anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The mass of the salix psammophila extract accounts for 15% of the total mass of the skin conditioner.
Wherein the skin conditioner also comprises a mixture of nicotinamide, glycolipid, oat kernel oil and phytosterol/octyldodecanol lauroyl glutamate, and the mass ratio of the nicotinamide, the glycolipid, the oat kernel oil and the phytosterol/octyldodecanol lauroyl glutamate is 1:1:3: 1.
The polyalcohol is a mixture of aminomethyl propanol and butanediol, and the mass ratio of the aminomethyl propanol to the butanediol is 1: 2;
the humectant is a mixture of sodium hyaluronate, glucan and a bonatespirulina extract, and the mass ratio of the sodium hyaluronate to the glucan to the bonatespirulina extract is 1:3: 2;
the emollient is a mixture of octyl dodecanol, polyhydroxystearic acid, octyl dodecanol myristate, argania spinosa kernel oil and squalane and oat kernel oil, and the mixture of the five is 1:3:1:2: 2.
The emulsifier is a mixture of polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax and cetyl alcohol, and the mass ratio of the polyglycerol-6 distearate to the jojoba esters is 1:2:1: 2;
the thickening agent is a mixture of carbomer and acacia gum, and the mass ratio of the carbomer to the acacia gum is 1: 1;
the pH regulator is a mixture of triethanolamine, arginine and citric acid, and the mass ratio of the triethanolamine, the arginine and the citric acid is 1:3: 1;
the antioxidant is a mixture of a mulberry extract wrapping oxyresveratrol, superoxide dismutase and tocopherol acetate, and the mass ratio of the mulberry extract to the superoxide dismutase to the tocopherol acetate is 1:1: 1;
the preservative is a mixture of ethylhexyl glycerol, p-hydroxyacetophenone and 1, 2-hexanediol, and the mass ratio of the ethylhexyl glycerol to the p-hydroxyacetophenone to the 1, 2-hexanediol is 1:5: 1.
The anti-aging and face-brightening nutrient containing the golden willow extract is prepared by the following method, and the preparation method comprises the following steps:
and 4, adding an antioxidant, a skin conditioner and a preservative into the main pot in sequence, stirring uniformly, and cooling to room temperature to form the nutrient.
The essence containing the golden fragrant willow extract comprises the nutrient containing the golden fragrant willow extract and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1:3 percent of the components are mixed.
Wherein the emulsion comprises a mixture of dicetyl phosphate, magnolol/honokiol and mulberry extract, the mass ratio of the dicetyl phosphate, the magnolol/honokiol and the mulberry extract is 1:3:1, the diameter of vesicles of the emulsion is 180nm,
the extraction method of the golden fragrant willow extract comprises the following steps:
(1) picking 1.2kg of golden willow leaves, cleaning, and soaking in 1200ml of 95% ethanol by volume for 71H;
(2) extracting for the first time at 2.5 deg.C for 3.2H, filtering, extracting for the second time at 3.2 deg.C for 3.5H, and mixing the two extractive solutions to obtain extractive solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) and dispersing the concentrated solution in 850ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
Example 3
The anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The mass of the golden fragrant willow extract accounts for 20% of the total mass of the skin conditioner.
Wherein the skin conditioning agent further comprises niacinamide.
The polyalcohol is a mixture of aminomethyl propanol and dipropylene glycol, and the mass ratio of the aminomethyl propanol to the dipropylene glycol is 1: 3;
the humectant is a mixture of panthenol, erythritol and trehalose, and the mass ratio of the panthenol to the erythritol to the trehalose is 1:3: 1;
the emollient is a mixture of polyhydroxystearic acid and octyldodecanol myristate, and the mass ratio of the polyhydroxystearic acid to the octyldodecanol myristate is 1: 5;
the emulsifier is a mixture of cetyl alcohol, C10-18 fatty acid triglycerides and polyhydroxystearic acid, and the mass ratio of the cetyl alcohol to the C10-18 fatty acid triglycerides to the polyhydroxystearic acid is 1:3: 5;
the thickening agent is a mixture of carbomer and xanthan gum, and the mass ratio of the carbomer to the xanthan gum is 1: 3;
the pH regulator is sodium citrate;
the antioxidant is a mixture of superoxide dismutase and tocopherol acetate, and the mass ratio of the superoxide dismutase to the tocopherol acetate is 1: 5;
the preservative is a mixture of ethylhexyl glycerol and 1, 2-hexanediol, and the mass ratio of the ethylhexyl glycerol to the 1, 2-hexanediol is 1: 4.
The anti-aging and face-brightening nutrient containing the golden willow extract is prepared by the following method, and the preparation method comprises the following steps:
and 4, adding an antioxidant, a skin conditioner and a preservative into the main pot in sequence, stirring uniformly, and cooling to room temperature to form the nutrient.
The essence containing the golden fragrant willow extract comprises the nutrient containing the golden fragrant willow extract and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1:5 percent of the components are mixed.
Wherein the emulsion comprises a mixture of dicetyl phosphate and mulberry extract, the mass ratio of dicetyl phosphate to mulberry extract is 1:3, the diameter of the vesicle of the emulsion is 200nm,
the extraction method of the golden fragrant willow extract comprises the following steps:
(1) picking 1.5kg of golden willow leaves, cleaning, and soaking in 1500ml of ethanol with the volume fraction of 95% for 71H;
(2) extracting for the first time 3H at a low temperature of 3 ℃, filtering, extracting for the second time 3H at a low temperature of 3 ℃, and mixing the liquid extracted for the second time to prepare an extracting solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution in 900ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
Example 4
The anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The mass of the golden fragrant willow extract accounts for 25% of the total mass of the skin conditioner.
The skin conditioner also comprises a mixture of an umbilical cord extract, placental protein and placental enzyme, wherein the mass ratio of the umbilical cord extract to the placental protein to the placental enzyme is 1:3: 4.
The polyalcohol is a mixture of dipropylene glycol and glycerol, and the mass ratio of the dipropylene glycol to the glycerol is 1: 6;
the humectant is a mixture of sodium hyaluronate, dextran, erythritol and trehalose, and the mass ratio of the sodium hyaluronate to the dextran to the erythritol is 1:1:1: 3;
the emollient is a mixture of shea butter, octyl dodecanol myristate and oat kernel oil, and the mass ratio of the shea butter, the octyl dodecanol myristate and the oat kernel oil is 1:2: 3;
the emulsifier is a mixture of stearyl stearate and behenic acid, and the mass ratio of the stearyl stearate to the behenic acid is 1: 3;
the thickening agent is xanthan gum;
the pH regulator is citric acid;
the antioxidant is a mixture of tocopherol acetate, Daphnia hirta fruit oil and vitamin C, and the mass ratio of the tocopherol acetate, the Daphnia hirta fruit oil and the vitamin C is 1:3: 1;
the preservative is a mixture of 1, 2-pentanediol, glyceryl caprylate and caprylyl hydroximic acid, and the mass ratio of the 1, 2-pentanediol, the glyceryl caprylate and the caprylyl hydroximic acid is 1:3: 3.
The anti-aging and face-brightening nutrient containing the golden willow extract is prepared by the following method, and the preparation method comprises the following steps:
and 4, adding an antioxidant, a skin conditioner and a preservative into the main pot in sequence, stirring uniformly, and cooling to room temperature to form the nutrient.
The essence containing the golden fragrant willow extract comprises the nutrient containing the golden fragrant willow extract and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1: 8 percent of the components are mixed.
Wherein the emulsion comprises sorbitan esters, and the vesicle diameter of the emulsion is 220 nm.
The extraction method of the golden fragrant willow extract comprises the following steps:
(1) picking 1.7kg of golden willow leaves, cleaning, and soaking in 1700ml of ethanol with the volume fraction of 95% for 71H;
(2) extracting for the first time 3H at a low temperature of 3 ℃, filtering, extracting for the second time 3H at a low temperature of 3 ℃, and mixing the liquid extracted for the second time to prepare an extracting solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution into 950ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
Example 5
The anti-aging and beautifying nutrient containing the golden fragrant willow extract comprises the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
The mass of the golden fragrant willow extract accounts for 30% of the total mass of the skin conditioner.
Wherein the skin conditioner also comprises nicotinamide, glycolipid, oat kernel oil, cedar bud extract, phytosterol/octyldodecanol lauroyl glutamate, schizosaccharomyces cerevisiae fermentation product lysate, umbilical cord extract, placental protein and placental enzyme, and the mass ratio of the nine is 1:1:1:2:1:1:1:2: 1.
The polyalcohol is a mixture of aminomethyl propanol, butanediol, dipropylene glycol and glycerol, and the mass ratio of the four is 1:2:1: 1;
the humectant is a mixture of sodium hyaluronate, dextran, a bonatespirulina extract, panthenol, erythritol and trehalose, and the mass ratio of the sodium hyaluronate to the dextran to the bornate spirulina extract is 1:2:1:1:2: 1;
the emollient is a mixture of octyl dodecanol, polyhydroxystearic acid, octyl dodecanol myristate, argania spinosa kernel oil, squalane and oat kernel oil, and the mass ratio of the octyl dodecanol, the polyhydroxystearic acid, the octyl dodecanol myristate, the argania spinosa kernel oil, the squalane and the oat kernel oil is 1:2:1:1:2: 1;
the emulsifier is a mixture of polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax, cetyl alcohol, triglyceride C10-18 fatty acid, polyhydroxystearic acid, candelilla wax, stearyl behenate and cetyl stearate, and the mass ratio of the polyglycerol-6 distearate to the glyceryl tribasic ester C10-18 fatty acid is 1:1:2:1:1:1:2: 1;
the thickening agent is a mixture of carbomer, acacia gum and xanthan gum, and the mass ratio of the carbomer to the acacia gum to the xanthan gum is 1:0.5: 1;
the pH regulator is a mixture of triethanolamine, arginine, citric acid and sodium citrate, and the mass ratio of the triethanolamine, the arginine, the citric acid and the sodium citrate is 1:3:1: 1;
the antioxidant is a mixture of mulberry extract wrapping oxyresveratrol, superoxide dismutase, tocopherol acetate, Daphnia hirta fruit oil, vitamin C and anthocyanin, and the mass ratio of the mulberry extract to the superoxide dismutase is 1:3:1:1: 2;
the preservative is a mixture of ethylhexyl glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, 1, 2-pentanediol, glyceryl caprylate and caprylyl hydroximic acid, and the mass ratio of the ethylhexyl glycerol to the p-hydroxyacetophenone to the caprylyl hydroximic acid is 1:3:1:1: 2.
The anti-aging and face-brightening nutrient containing the golden willow extract is prepared by the following method, and the preparation method comprises the following steps:
and 4, adding an antioxidant, a skin conditioner and a preservative into the main pot in sequence, stirring uniformly, and cooling to room temperature to form the nutrient.
The essence containing the golden fragrant willow extract comprises the nutrient containing the golden fragrant willow extract and a milk with tiny vesicles, wherein the nutrient is prepared by the preparation method, and the essence is prepared from the nutrient and the milk in a mass ratio of 1: 10 percent of the components are mixed.
Wherein the emulsion comprises at least one of 6-functional polyglycerol ester, 10-functional polyglycerol ester, sorbitan ester, dicetyl phosphate, magnolol/honokiol, and mulberry extract, and the diameter of the vesicle of the emulsion is 250 nm.
The extraction method of the golden fragrant willow extract comprises the following steps:
(1) picking 2kg of golden willow leaves, cleaning, and soaking in 2000ml of ethanol with the volume fraction of 95% for 72H;
(2) extracting for the first time at 4 deg.C for 4H, filtering, extracting for the second time at 4 deg.C for 4H, and mixing the two extractive solutions to obtain extractive solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution into 1000ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
The vesicle center of the emulsion of the invention is formed by an aqueous cavity surrounded by one or more bilayers formed by amphiphilic molecules.
The essences in the above five examples were selected for testing, and a total of 250 volunteers (age between 19-40 years) were subjected to a seven-day follow-up test, and skin water content, epidermal water loss rate, skin elasticity and skin imaging analysis (test instruments: DJM e pigment skin detector, Deflin VapoMeter transdermal water loss measuring instrument, Deflin moistuturemeter epid 0.5mm epidermal water content measuring instrument, Miravex astera 3D skin imaging analyzer, CK skin water content test probe CM825 and CK skin elasticity testing instrument current meter dual MPA580) were measured, using rules: the lotion is used after being cleaned and moisturized in the morning and evening, and the dosage of the lotion is 30ml sample bottles of a laboratory 4 pumps, and the lotion is smeared on the whole face and is lightly tapped until being absorbed.
Test 1: the test for fading fine lines around eyes is shown in fig. 1a and fig. 1b, and it can be seen from fig. 1a that the fine lines under eyes are preliminarily improved after the volunteer uses the essence of the invention for 3 days, and it can be seen from fig. 1b that the fine lines under eyes are obviously faded after the volunteer uses the essence of the invention for 7 days;
In the above tests, T0 is the detection of the skin before the product is not used on the first day, T1 is the detection data of the product used for the first time on the first day after half an hour, T2 is the detection data of the same time on the second day, T3 is the detection data of the same time on the third day, T4 is the detection data of the same time on the fourth day, and so on, T8 is the detection data of the same time on the eighth day, and all the test data are measured in a safety efficacy assessment laboratory at a temperature of 20-22 ℃ and a humidity of 45% -55%.
The pH value of the essence is 4.0-8.5, the relative density (20 ℃/20 ℃) is 0.9533-1.0533, and the essence can balance the generation of melanin and has the effects of whitening, improving the skin luster, improving facial flaws and the like. It can restore the balance of melanocyte and restore the natural color and luster of skin. The skin care product can effectively capture free radicals, prevent skin photoaging, obviously reduce wrinkles, increase skin elasticity, increase skin barrier and reduce water loss, and has no stimulation to skin.
The above disclosure is only for the purpose of illustrating the preferred embodiments of the present invention and should not be taken as limiting the scope of the present invention.
Claims (10)
1. The anti-aging and beautifying nutrient containing the golden fragrant willow extract is characterized by comprising the following components in parts by weight:
the skin conditioner contains extract of Salix psammophila.
2. The anti-aging and skin-brightening nutrient containing the golden fragrant willow extract according to claim 1, wherein the mass of the golden fragrant willow extract accounts for 10-30% of the total mass of the skin conditioner.
3. The anti-premature skin lightening nutrient containing golden fragrant willow extract according to claim 1, characterized in that the skin conditioner further comprises at least one of niacinamide, glycolipids, oat kernel oil, cedar bud extract, phytosterols/octyldodecanol lauroyl glutamate, yeast dehiscence lysate, umbilical cord extract, placental protein and placental enzyme.
4. The anti-aging and beautifying nutrient containing the golden fragrant willow extract according to claim 1, characterized by further comprising a preservative in an amount of 0.5-1 part by weight;
the polyalcohol is at least one of aminomethyl propanol, butanediol, dipropylene glycol and glycerol;
the humectant is at least one of sodium hyaluronate, dextran, Bolinate Spirulina extract, panthenol, erythritol and trehalose;
the emollient is at least one of shea butter, octyl dodecanol, polyhydroxystearic acid, octyl dodecanol myristate, isononyl isononanoate, argania spinosa kernel oil, squalane and oat kernel oil;
the emulsifier is at least one of polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax, cetyl alcohol, triglyceride C10-18 fatty acid, polyhydroxystearic acid, candelilla wax, stearyl behenate, cetyl stearate, stearyl stearate and behenic acid;
the thickening agent is at least one of carbomer, acacia gum and xanthan gum;
the pH regulator is at least one of triethanolamine, arginine, citric acid and sodium citrate;
the antioxidant is at least one of mulberry extract, superoxide dismutase, tocopherol acetate, Pterocarpus marsupium fruit oil, vitamin C and anthocyanin which wrap the oxyresveratrol;
the preservative is at least one of ethylhexyl glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, 1, 2-pentanediol, glyceryl caprylate and caprylyl hydroximic acid.
5. The method for preparing the anti-aging and skin-brightening nutrient containing the golden fragrant willow extract according to any one of claims 1 to 4, which is characterized by comprising the following steps:
step 1, adding polyalcohol, a humectant and a thickener into a main pot, adding deionized water, heating and stirring to 75-85 ℃ until the polyalcohol, the humectant and the thickener are completely dissolved to form a water phase, adding an emollient and an emulsifier into an oil phase pot, heating and stirring to 75-85 ℃ until the emollient and the emulsifier are completely dissolved to form an oil phase;
step 2, pumping the oil phase in the oil phase pot into a main pot, stirring, homogenizing and emulsifying at the constant temperature of 75-85 ℃, and stirring and cooling for later use;
step 3, adding a pH regulator into the main pot while stirring until the mixture is uniformly stirred;
and 4, sequentially adding an antioxidant and a skin conditioner into the main pot, uniformly stirring, and cooling to room temperature to form the nutrient.
6. An essence containing a gold fragrant willow extract, which is characterized by comprising a nutrient and a milk with small vesicles, wherein the nutrient is prepared according to the preparation method of claim 5, and the essence is prepared from the nutrient and the milk in a mass ratio of 1:1 to 10 percent of the raw materials.
7. The serum of claim 6, wherein the emulsion comprises at least one of 6 functional polyglycerol esters, 10 functional polyglycerol esters, sorbitan esters, dicetyl phosphate, magnolol/honokiol, and mulberry extract.
8. The essence of claim 7, wherein the emulsion has a vesicle diameter of 150-250 nm, the vesicle is formed by an aqueous cavity in the center and one or more bilayers formed by amphiphilic molecules around the cavity.
9. The extraction method of the golden fragrant willow extract is characterized by comprising the following steps:
(1) picking 1-2 kg of golden willow leaves, cleaning, and then soaking in 1000-2000 ml of ethanol with the volume fraction of 95% for 70-72H;
(2) extracting at the low temperature of 2-4 ℃ to prepare an extracting solution;
(3) concentrating the extracting solution to prepare a concentrated solution;
(4) dispersing the concentrated solution into 800-1000 ml of butanediol with the volume fraction of 20%, and finely filtering to obtain the golden fragrant willow extract.
10. The extraction method of the golden fragrant willow extract according to claim 9, wherein the step (2) is specifically as follows: extracting for the first time for 3-4H at the low temperature of 2-4 ℃, filtering, extracting for the second time for 3-4H at the low temperature of 2-4 ℃, and mixing the two extracted liquids to prepare the extracting solution.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112826762A (en) * | 2021-01-07 | 2021-05-25 | 广州艾蓓生物科技有限公司 | Bicontinuous microemulsion composition and application thereof |
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| CN112826762A (en) * | 2021-01-07 | 2021-05-25 | 广州艾蓓生物科技有限公司 | Bicontinuous microemulsion composition and application thereof |
| CN112915060A (en) * | 2021-04-19 | 2021-06-08 | 广州广妆生物科技有限公司 | Emulsion containing anti-aging composition and preparation method thereof |
| CN114836275A (en) * | 2022-04-18 | 2022-08-02 | 重庆菩璞生物科技有限公司 | Antibacterial gold fragrant willow handmade soap and preparation process thereof |
| CN114796094A (en) * | 2022-04-28 | 2022-07-29 | 重庆菩璞生物科技有限公司 | Golden fragrant willow sachet and preparation method thereof |
| CN114796094B (en) * | 2022-04-28 | 2024-01-23 | 重庆菩璞生物科技有限公司 | Gold aroma Liu Xiangnang and preparation method thereof |
| CN115154403A (en) * | 2022-08-25 | 2022-10-11 | 广州阿基米德生物科技有限公司 | Skin repair composition and preparation method and application thereof |
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Application publication date: 20200728 |