CN114502959A - 用于检测tp抗体的试剂盒以及方法 - Google Patents
用于检测tp抗体的试剂盒以及方法 Download PDFInfo
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- CN114502959A CN114502959A CN201980101128.8A CN201980101128A CN114502959A CN 114502959 A CN114502959 A CN 114502959A CN 201980101128 A CN201980101128 A CN 201980101128A CN 114502959 A CN114502959 A CN 114502959A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
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- Immunology (AREA)
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- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
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- Tropical Medicine & Parasitology (AREA)
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- Microbiology (AREA)
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- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
Abstract
一种梅毒螺旋体(TP)抗体免疫检测中所使用的酶标记物，该酶标记物为标记用酶与TP抗原性蛋白的融合蛋白。一种用于检测TP抗体的试剂盒及检测样本中感染梅毒螺旋体(TP)后产生的抗体的方法，该试剂盒包括标记用酶与TP抗原性蛋白的融合蛋白。其中，抗原性蛋白含有TP15抗原、TP17抗原、TP47抗原和TP45抗原中的一种或更多种，或其中的两种以上的融合抗原。
Description
PCT国内申请，说明书已公开。
Claims (17)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2019/111056 WO2021072599A1 (zh) | 2019-10-14 | 2019-10-14 | 用于检测tp抗体的试剂盒以及方法 |
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| Publication Number | Publication Date |
|---|---|
| CN114502959A true CN114502959A (zh) | 2022-05-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980101128.8A Pending CN114502959A (zh) | 2019-10-14 | 2019-10-14 | 用于检测tp抗体的试剂盒以及方法 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN114502959A (zh) |
| WO (1) | WO2021072599A1 (zh) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60169498A (ja) * | 1984-02-10 | 1985-09-02 | Kyowa Hakko Kogyo Co Ltd | 成人ｔ細胞白血病ウイルス抗原ペプチド誘導体 |
| US5578456A (en) * | 1994-02-28 | 1996-11-26 | Fujirebio Inc. | Anti-treponema pallidum antibody immunoassay |
| EP0985931A3 (en) * | 1998-09-04 | 2000-03-29 | Becton Dickinson and Company | Recombinant antigen immunoassay for the diagnosis of syphilis |
| CN1609222A (zh) * | 2003-10-21 | 2005-04-27 | 中国科学院微生物研究所 | 一种碱性磷酸酶基因及其编码蛋白与应用 |
| JP5081462B2 (ja) * | 2007-02-02 | 2012-11-28 | 富士フイルム株式会社 | トランススプライシング法による融合タンパク質作製方法 |
| CN101948545B (zh) * | 2010-09-08 | 2013-06-19 | 潍坊医学院 | IgG抗体亲和肽-碱性磷酸酶融合蛋白 |
| CN103014012B (zh) * | 2012-12-26 | 2014-09-10 | 华中农业大学 | 镰刀菌特异单链抗体及制备方法和应用 |
| CN104569392A (zh) * | 2013-10-28 | 2015-04-29 | 广州市康润生物科技有限公司 | 一种检测梅毒特异性IgM抗体的ELISA试剂盒及其制备方法 |
| DE102014011653A1 (de) * | 2014-06-20 | 2015-12-24 | Ulrich Loos | Nachweis von Autoantikörpern gegen den TSH-Rezeptor |
| CN108239651B (zh) * | 2016-12-23 | 2021-10-01 | 广州呼吸疾病研究所 | 一种重组融合碱性磷酸酶-过敏原蛋白及其制备方法和应用 |
| CN110456052A (zh) * | 2019-08-22 | 2019-11-15 | 中国科学院武汉病毒研究所 | 一种血清中梅毒螺旋体抗体的快速检测方法及其应用 |
-
2019
- 2019-10-14 WO PCT/CN2019/111056 patent/WO2021072599A1/zh active Application Filing
- 2019-10-14 CN CN201980101128.8A patent/CN114502959A/zh active Pending
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| Publication number | Publication date |
|---|---|
| WO2021072599A1 (zh) | 2021-04-22 |
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