CN114375332B - 谷氨酰胺合成酶的修饰多肽及使用其生产l-谷氨酰胺的方法 - Google Patents

谷氨酰胺合成酶的修饰多肽及使用其生产l-谷氨酰胺的方法 Download PDF

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CN114375332B
CN114375332B CN202180004868.7A CN202180004868A CN114375332B CN 114375332 B CN114375332 B CN 114375332B CN 202180004868 A CN202180004868 A CN 202180004868A CN 114375332 B CN114375332 B CN 114375332B
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amino acid
glutamine
polypeptide
seq
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CN114375332A (zh
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崔秀真
李任相
金希英
金柄秀
李光雨
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CJ CheilJedang Corp
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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    • C12Y603/01—Acid-ammonia (or amine)ligases (amide synthases)(6.3.1)
    • C12Y603/01002—Glutamate-ammonia ligase (6.3.1.2)
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CN202180004868.7A 2020-03-04 2021-03-04 谷氨酰胺合成酶的修饰多肽及使用其生产l-谷氨酰胺的方法 Active CN114375332B (zh)

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Application Number Priority Date Filing Date Title
KR10-2020-0027322 2020-03-04
KR1020200027322A KR102198072B1 (ko) 2020-03-04 2020-03-04 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법
PCT/KR2021/002652 WO2021177731A1 (ko) 2020-03-04 2021-03-04 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법

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CN114375332A CN114375332A (zh) 2022-04-19
CN114375332B true CN114375332B (zh) 2024-01-12

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US (1) US12270061B2 (https=)
EP (1) EP3954767A4 (https=)
JP (2) JP7371119B2 (https=)
KR (1) KR102198072B1 (https=)
CN (1) CN114375332B (https=)
BR (1) BR112021022223B1 (https=)
WO (1) WO2021177731A1 (https=)

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KR102198072B1 (ko) 2020-03-04 2021-01-04 씨제이제일제당 주식회사 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법
WO2022108383A1 (ko) 2020-11-20 2022-05-27 씨제이제일제당 (주) L-글루타민 생산능이 향상된 미생물 및 이를 이용한 l-글루타민 생산 방법

Citations (3)

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EP1460128A1 (en) * 2003-03-03 2004-09-22 Ajinmoto Co., Inc. Method for producing L-arginine or L-lysine by fermentation
CN1884501A (zh) * 2006-06-29 2006-12-27 清华大学 谷氨酰胺合成酶及其专用表达工程菌与应用
KR20130105380A (ko) * 2012-03-12 2013-09-25 한화케미칼 주식회사 변이된 글루타민 합성효소 유전자를 포함하는 벡터 및 이를 이용한 목적 단백질의 생산방법

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US20060269975A1 (en) * 1999-07-16 2006-11-30 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in DNA replication, protein synthesis, and pathogenesis
JP4560998B2 (ja) 2001-02-05 2010-10-13 味の素株式会社 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌
RU2230114C2 (ru) * 2001-11-30 2004-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот
JP2004187684A (ja) * 2002-11-26 2004-07-08 Ajinomoto Co Inc Ｌ−グルタミンの製造法及びｌ−グルタミン生産菌
JP4576850B2 (ja) 2003-03-03 2010-11-10 味の素株式会社 発酵法によるｌ−アルギニン又はｌ−リジンの製造法
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
JP5048996B2 (ja) 2006-11-10 2012-10-17 昭和電工株式会社 加工性に優れた耐摩耗性アルミニウム合金材およびその製造方法
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KR102198072B1 (ko) 2020-03-04 2021-01-04 씨제이제일제당 주식회사 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법

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EP1460128A1 (en) * 2003-03-03 2004-09-22 Ajinmoto Co., Inc. Method for producing L-arginine or L-lysine by fermentation
CN1884501A (zh) * 2006-06-29 2006-12-27 清华大学 谷氨酰胺合成酶及其专用表达工程菌与应用
KR20130105380A (ko) * 2012-03-12 2013-09-25 한화케미칼 주식회사 변이된 글루타민 합성효소 유전자를 포함하는 벡터 및 이를 이용한 목적 단백질의 생산방법

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JP2022529297A (ja) 2022-06-20
WO2021177731A1 (ko) 2021-09-10
CN114375332A (zh) 2022-04-19
JP2023110008A (ja) 2023-08-08
EP3954767A1 (en) 2022-02-16
US12270061B2 (en) 2025-04-08
JP7371119B2 (ja) 2023-10-30
BR112021022223B1 (pt) 2023-09-26
BR112021022223A2 (pt) 2022-09-20
KR102198072B1 (ko) 2021-01-04
US20220396815A1 (en) 2022-12-15
EP3954767A4 (en) 2022-08-03

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