CN114306161A - Anti-aging composition and preparation method and application thereof - Google Patents
Anti-aging composition and preparation method and application thereof Download PDFInfo
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- CN114306161A CN114306161A CN202210007515.9A CN202210007515A CN114306161A CN 114306161 A CN114306161 A CN 114306161A CN 202210007515 A CN202210007515 A CN 202210007515A CN 114306161 A CN114306161 A CN 114306161A
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Abstract
The invention discloses an anti-aging composition, which consists of plant extracts and basic components, wherein the plant extracts account for 3.3-34% of the total mass of the composition according to the mass percentage, the basic components account for 66-96.7% of the total mass of the composition, the plant extracts comprise bistort rhizome extracts, pea extracts and citrus peel extracts, and the basic components comprise solvents, preservatives and thickening agents; the composition can effectively remove free radicals and promote the generation of collagen and elastin, and also discloses a production method and application of the composition.
Description
Technical Field
The invention discloses a composition, in particular to an anti-aging composition, a preparation method and application thereof, belonging to the technical field of cosmetics.
Background
The skin is the outermost tissue of the human body and plays a role in protecting the human body from external injury and resisting various external mechanical, chemical, physical and biological stimuli. Human skin aging is classified into endogenous aging, which is an aging process occurring with the increase of age under the influence of genetic factors, and exogenous aging, which is aging caused by the influence of the environment on the skin. The main factor of environmental impact is the damage of free radicals, which are abundant in active oxygen free radicals in our living environment. The damage of free radicals to human skin is mainly caused by lipid peroxidation, protein peroxidation and DNA damage, which continuously attack and destroy the outer cellular tissues of the human body through strong oxidative reactions. Therefore, signal transduction of human cells is disturbed, apoptosis is accelerated, skin aging is accelerated, and a series of chronic skin health problems such as dry skin, laxity, desquamation, melanin increase, and even skin spots are caused, which afflict many consumers.
Scavengers of free radicals, known as antioxidants, achieve antioxidant action by inhibiting or terminating the oxygen radical chain reaction. In recent years, with the increasing demands of people on cosmetics, such as safety, high efficiency, no stimulation and the like, the natural antioxidant of plant source is increasingly emphasized due to the characteristics of wide source, safety, effectiveness, natural, no toxicity and the like. Natural antioxidants are of various types and generally include superoxide dismutase, catalase, glutathione, carnosine, vitamin C, vitamin E, plant polyphenols, flavonoids, carotenoids, etc.
At present, many anti-aging and anti-wrinkle products on the market supplement collagen and elastin in the skin, or use a single antioxidant to reduce the generation of free radicals to achieve the anti-aging purpose. However, most of substances contained in the composition are macromolecules which are difficult to absorb by skin, and in addition, antioxidants are often irritant to a certain extent, and the risk of easy inactivation exists, so that the antioxidant and anti-aging effects are not ideal.
In summary, the antioxidant and anti-aging products which can effectively remove free radicals and promote the production of collagen and elastin are developed through the combination of plant extracts at present, and the antioxidant and anti-aging products have wide market application prospects.
Disclosure of Invention
In view of the above-mentioned disadvantages, the present invention provides an anti-aging composition, which can effectively remove free radicals and promote the production of collagen and elastin, and can be applied to cosmetics to enhance the connection between dermis and epidermis, supplement collagen and elastin, remove free radicals and the like, and resist aging in multiple dimensions, so as to achieve the effects of resisting oxidation, improving skin color, reducing wrinkles and increasing skin elasticity.
Therefore, the first technical scheme provided by the invention is as follows:
an anti-aging composition comprises plant extracts and basic components, wherein the plant extracts account for 3.3-34% of the total mass of the composition, the basic components account for 66-96.7% of the total mass of the composition, the plant extracts comprise bistort rhizome extracts, pea extracts and citrus peel extracts, and the basic components comprise solvents, preservatives and thickeners.
Preferably, the weight ratio of the bistort rhizome extract, the pea extract and the citrus peel extract is (5-30): 1-5): 10-50.
Preferably, the weight ratio of the bistort rhizome extract, the pea extract and the citrus peel extract is (10-20): (3-5): (20-40).
Further, the weight ratio of the bistort rhizome extract to the pea extract to the citrus peel extract is 10:3: 20.
Preferably, the solvent is one or more of water, butanediol, propylene glycol, glycerol, pentanediol and hexanediol. The preservative is one or more of preservatives or preservative aids on the market, such as propylene glycol, butanediol, pentanediol, hexanediol, caprylyl glycol, ethylhexyl glycerol, p-hydroxyacetophenone, caprylyl hydroxamic acid, phenoxyethanol, potassium sorbate, sodium benzoate and the like. The thickening agent is one or more of acrylic acid (ester) copolymer sodium, lecithin, hydrogenated lecithin, polyacrylate cross-linked polymer-6, carbomer sodium, sodium polyacryl dimethyl taurate, ammonium acryloyl dimethyl taurate/VP copolymer and xanthan gum.
Preferably, the base component consists of water, hexanediol, caprylyl glycol, sodium acrylate copolymer and lecithin.
Preferably, in the base component, the hexanediol accounts for 0.5-5% of the total mass of the base component, the caprylyl glycol accounts for 0.05-0.5% of the total mass of the base component, the acrylic acid (ester) copolymer sodium accounts for 0.4-0.8% of the total mass of the base component, the lecithin accounts for 0.1-0.5% of the total mass of the base component, and the water accounts for 93.2-98.95% of the total mass of the base component in percentage by mass.
The application also discloses a preparation method of the anti-aging composition, which comprises the following steps:
step one, adding acrylic acid (ester) copolymer sodium and lecithin into deionized water, soaking for 30-60min, and fully swelling to obtain a solution a for later use;
step two, adding the pea extract into deionized water which is about 10 times of the weight of the pea extract, stirring and dissolving the pea extract at room temperature, adding the pea extract into the solution a, heating the solution to 70-80 ℃, homogenizing the solution for 3-5min under the condition of 15-35 Hz, and stirring the solution for 10-20 min under the condition of 150-500 rpm until the solution is uniformly dispersed;
step three, cooling to 45-55 ℃, adding the bistort rhizome extract under stirring, and continuing stirring for 3-5min until the bistort rhizome extract is uniformly dispersed;
and step four, cooling to below 45 ℃, sequentially adding the mixed solution of the citrus peel extract, the hexanediol and the caprylyl glycol, uniformly stirring, and cooling to room temperature to obtain the composition.
The application also discloses application of the anti-aging composition in preparing anti-aging cosmetics.
Preferably, the cosmetic is a skin external preparation prepared by taking the anti-aging composition as an active component and adding conventional pharmaceutical or cosmetic auxiliary materials or auxiliary components.
Preferably, the anti-ageing composition in the cosmetic accounts for 1.5-25 wt% of the total weight of the cosmetic.
Preferably, the anti-aging cosmetic is one or more of astringent, essence, lotion, cream and facial mask.
Further, the application also discloses a skin care product containing the anti-aging composition, which consists of the following components: 1.0 to 5.0 percent of butanediol, 0.01 to 0.05 percent of ethylene diamine tetraacetic acid disodium salt, 5.0 to 10.0 percent of glycerol, 0.5 to 0.8 percent of acryloyl dimethyl taurate/VP copolymer, 0.1 to 0.15 percent of xanthan gum, 3.5 to 4.5 percent of isotridecanol isononanoate, 1.0 to 1.5 percent of jojoba seed oil, 1.0 to 1.5 percent of squalane, 1.0 to 1.5 percent of hexyl laurate, 0.05 to 0.2 percent of cetyl alcohol, 0.05 to 0.2 percent of methyl glucose sesquistearate, 0.1 to 0.3 percent of polyglycerol-3 methyl glucose distearate, 1.5 to 25.0 percent of anti-ageing composition, 0.5 to 2.0 percent of plant composite relieving component, 0.5 to 1.5 percent of preservative, 0.01 to 0.05 percent of essence and the balance of deionized water.
Furthermore, the application also discloses a preparation method of the skin care product containing the anti-aging composition, which comprises the following steps:
step one, weighing the following components as raw materials by weight: 1.0-5.0% of butanediol, 0.01-0.05% of ethylene diamine tetraacetic acid disodium salt, 5.0-10.0% of glycerol, 0.5-0.8% of acryloyl dimethyl taurate/VP copolymer, 0.1-0.15% of xanthan gum, 3.5-4.5% of isotridecanol isononanoate, 1.0-1.5% of jojoba seed oil, 1.0-1.5% of squalane, 1.0-1.5% of hexyl laurate, 0.05-0.2% of cetyl alcohol, 0.05-0.2% of methyl glucose sesquistearate, 0.1-0.3% of polyglycerol-3 methyl glucose distearate, 1.5-25.0% of anti-ageing composition, 0.5-2.0% of plant composite soothing component, 0.5-1.5% of preservative, 0.01-0.05% of essence and the balance of deionized water;
step two, spraying the acryloyl dimethyl ammonium taurate/VP copolymer into deionized water with the mass of 25% of the raw material in the step 1), standing for 2-4h to ensure that the copolymer fully absorbs water and swells to obtain a mixture A, and heating to 60-70 ℃;
step three, sequentially adding disodium ethylene diamine tetraacetate, xanthan gum, glycerol and butanediol into deionized water accounting for 40% of the mass of the raw materials in the step 1), stirring for 10-20 min, and heating to 75-85 ℃ to obtain a mixture B;
step four, adding the oil phase which is preheated and dissolved into the solution B in sequence, wherein the components comprise: isotridecanol isononanoate, jojoba seed oil, squalane, hexyl laurate, cetyl alcohol, methyl glucose sesquistearate and polyglycerol-3-methyl glucose distearate, homogenizing at high speed for 3-5min, stirring until the material body is uniform, adding the mixture A, homogenizing and stirring until no particles exist, keeping the temperature at 75-85 ℃, and stirring for 10-15min to obtain a mixture C;
and step five, cooling to the temperature below 45 ℃ by stirring, adding 1.5-25.0% of the anti-aging composition, 0.5-2.0% of the plant composite soothing component, 0.5-1.5% of the preservative and 0.01-0.05% of the essence into the mixture C, supplementing deionized water to 100%, and uniformly stirring to obtain the skin care product containing the anti-aging composition.
The bistort rhizome (Polygonum bistorta) extract used in the composition is an extract of dried rhizome of bistort rhizome (Polygonum bistorta) of Polygonaceae, and has the effects of clearing heat, relieving convulsion, regulating dampness, reducing swelling, relieving pain and the like in medicine. Can act on basement membrane proteoglycan and dystrophin proteoglycan, optimize the integrality of dermis-epidermis connecting layer and dermis blood vessel, and is helpful for recovering the steady state and the integrality of skin by improving the dynamic balance of the skin, so that the skin is brighter, the surface is smoother and more uniform, and the effects of resisting aging and increasing the skin luster are achieved. The bistort rhizome extract used in the composition of the present application is a commercially available cosmetic grade product, preferably bistort rhizome extract (hummer a00316) manufactured by BASF corporation, and is brown liquid in appearance, good in water solubility, pH (20 ℃): 4.0-7.0; density (20 ℃): 1.00-1.02g/m3(ii) a Solid content: 250 g/Kg; boiling range (1013 kpa): 90-110 degrees; the content of rhizoma Bistortae extract is 1 × 104-5×104ppm。
The pea (pisumastivum) extract used in the composition of the present application is an extract enriched in protease-resistant activity extracted from unique winter peas, and has a protease-resistant content 3-4 times higher than that of ordinary peas. The component adopts unique extraction/purification technology to remove high molecular weight compounds (in the seed)>100kDa) and then concentrated by ultrafiltration to remove small molecular weight compounds (C<5kDa) is a natural purified specific polypeptide fragment (5-30kDa polypeptide) and has the effects of making the skin totally recombinant and resisting aging. As used in the compositions of the present applicationThe pea extract is commercially available cosmetic grade, preferably pea extract from BASF corporation, is beige powder in appearance, has slight odor, is water soluble, and has pH (20 deg.C, 3% water solution): 4.5-6.5; bulk density (25 ℃): 100-600kg/m3(ii) a The content of pea extract is 50%.
The citrus (citrus reticulata) peel extract used in the composition is a citrus peel extract, and the citrus peel contains a certain amount of conventional ingredients such as water, grease, cellulose, minerals and the like, and also contains physiological active ingredients such as flavonoids, carotenoids and the like. The citrus peel extract has effects of eliminating various free radicals, and the main factors are flavonoids and hesperidin, so that the citrus peel extract is an ideal cosmetic antioxidant, can brighten skin and increase skin transparency, and has an anti-aging function by combining with the proliferation effect on fibroblasts. The specific preparation method comprises the following steps: slicing Mandarin orange pericarp, drying at 65 deg.C for 12 hr, pulverizing, and sieving with 60-100 mesh sieve. Taking dried pericarp powder and 70% ethanol according to a weight ratio of 1:10-15, extracting under boiling condition under hot reflux for 3 times, each time for 2h, stirring and standing, removing precipitate by centrifugal separation, taking supernatant, concentrating under reduced pressure until no alcohol smell exists to obtain orange pericarp primary extract, then adding 60% butanediol and 30% water of the total system, mixing and stirring uniformly, and filtering to obtain orange pericarp extract.
Compared with the prior art, the invention has the following beneficial effects:
1. in the anti-aging composition disclosed by the invention, a plurality of plant extracts including the bistort rhizome extract, the pea extract and the citrus peel extract are scientifically matched and synergized, wherein the bistort rhizome extract can increase the protein expression in keratinocytes, plays a multi-targeting role in different skin layers, repairs a dermis-epidermis connecting layer and achieves the effects of reducing wrinkles and improving skin luster; the pea extract is rich in protease, is a natural and purified specific polypeptide segment, and has the effects of comprehensively recombining the skin and increasing collagen and elastin; the citrus peel extract has good antioxidant effect, can brighten the skin, increase the transparent feeling of the skin, and also has a proliferation effect on fibroblasts, so that the anti-aging composition can resist aging in multiple dimensions from the aspects of enhancing the connection of dermis and epidermis, supplementing collagen and elastin, removing free radicals and the like, and achieves the effects of resisting oxidation, brightening the skin color, lightening wrinkles and increasing the skin elasticity.
2. The anti-aging composition disclosed by the invention is prepared from extracts of natural plants, is simple in component type, easy to prepare, safe and mild, is easy to mix with other components into a cosmetic formula, and has good market application prospect, wherein the cosmetics comprise astringent, essence, emulsion, cream, mask and the like.
Drawings
Figure 1 is the skin condition change of the subject at day 0/14/28 after use of the product of test 3.
Detailed Description
The following claims are hereby incorporated into the detailed description of the invention, with the understanding that the invention is not to be limited in any way, as any number of modifications may be made by one within the scope of the claims and the invention is still within the scope of the claims.
Example 1
An anti-aging composition comprises the following components: 1 g of bistort rhizome extract, 0.4 g of pea extract, 5 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 92.35 g of deionized water.
Example 2
An anti-aging composition comprises the following components: 2g of bistort rhizome extract, 0.5 g of pea extract, 8 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 88.25 g of deionized water.
Example 3
An anti-aging composition comprises the following components: 5 g of bistort rhizome extract, 1 g of pea extract, 10 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 82.75 g of deionized water.
Example 4
An anti-aging composition comprises the following components: 8 g of bistort rhizome extract, 1.5 g of pea extract, 15 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 74.25 g of deionized water.
Example 5
An anti-aging composition comprises the following components: 10 g of bistort rhizome extract, 2g of pea extract, 20 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 66.75 g of deionized water.
Comparative example 1
An anti-aging composition comprises the following components: 1 g of pea extract, 5 g of citrus peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 92.75 g of deionized water.
Comparative example 2
An anti-aging composition comprises the following components: 5 g of bistort rhizome extract, 8 g of orange peel extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 85.75 g of deionized water.
Comparative example 3
An anti-aging composition comprises the following components: 10 g of bistort rhizome extract, 2g of pea extract, 0.5 g of acrylic acid (ester) copolymer sodium, 0.2 g of lecithin, 0.5 g of hexanediol, 0.05 g of caprylyl glycol and 86.75 g of deionized water.
Preparation example
The preparation method of the anti-aging composition comprises the following steps:
step one, adding acrylic acid (ester) copolymer sodium and lecithin into deionized water, soaking for 45min, and fully swelling to obtain a solution a for later use;
step two, adding the pea extract into deionized water which is about 10 times of the weight of the pea extract, stirring and dissolving the pea extract at room temperature, adding the pea extract into the solution a, heating the solution to 75 ℃, homogenizing the solution for 4min under the condition of 25Hz, and stirring the solution for 15min under the condition of 325rpm until the pea extract is uniformly dispersed;
step three, cooling to 50 ℃, adding the bistort rhizome extract under stirring, and continuing stirring for 4min until the mixture is uniformly dispersed;
and step four, cooling to below 45 ℃, sequentially adding the mixed solution of the citrus peel extract, the hexanediol and the caprylyl glycol, uniformly stirring, and cooling to room temperature to obtain the composition.
TABLE 1, EXAMPLES 1-5 AND COMPARATIVE EXAMPLES 1-3 component tables
The composition with anti-aging effect can be used for preparing anti-aging cosmetics. The anti-aging cosmetic is a skin external preparation prepared by taking the composition with the anti-aging effect as an active component and adding conventional pharmaceutical or cosmetic auxiliary materials or auxiliary components. In specific use, the composition prepared by the invention is directly added into a cosmetic matrix, and the addition amount can be adjusted according to actual requirements, and is preferably 1.5-25 wt%.
Example of sample preparation
A skin care product containing an anti-aging composition is prepared from the following components: 3.0 g of butanediol, 0.05 g of ethylene diamine tetraacetic acid disodium salt, 7.0 g of glycerol, 0.5 g of acryloyl dimethyl taurate/VP copolymer, 0.1 g of xanthan gum, 3.9 g of isotridecanol isononanoate, 1.3 g of jojoba seed oil, 1.3 g of squalane, 1.3 g of hexyl laurate, 0.05 g of cetyl alcohol, 0.07 g of methyl glucose sesquistearate, 0.13 g of polyglycerol-3 methyl glucose distearate, 10 g of anti-aging composition, 1.5 g of plant composite soothing component, 1.0 g of preservative, 0.04 g of essence and 68.76 g of deionized water.
The preparation method of the skin care product containing the anti-aging composition comprises the following steps:
step one, spraying the acryloyl dimethyl ammonium taurate/VP copolymer into deionized water with the mass of 20% of the raw material, standing for 3 hours to enable the copolymer to fully absorb water and swell to obtain a mixture A, and heating to 65 ℃;
step two, sequentially adding disodium ethylene diamine tetraacetate, xanthan gum, glycerol and butanediol into deionized water with the mass of 40% of the raw materials, stirring for 15min, and heating to 80 ℃ to obtain a mixture B;
step three, adding the oil phase which is preheated and dissolved into the solution B in sequence, wherein the components comprise: isotridecanol isononanoate, jojoba seed oil, squalane, hexyl laurate, cetyl alcohol, methyl glucose sesquistearate and polyglycerol-3 methyl glucose distearate, homogenizing at high speed for 4min, stirring until the material body is uniform, adding the mixture A, homogenizing and stirring until no particles exist, keeping the temperature at 80 ℃, and stirring for 12.5min to obtain a mixture C;
and step four, cooling to below 45 ℃ by stirring, adding the anti-aging composition, the plant composite soothing component, the preservative and the essence into the mixture C, adding the rest deionized water, and uniformly stirring to obtain the skin care product containing the anti-aging composition.
In order to better illustrate the advantages of the present invention, the efficacy test of the anti-aging efficacy composition provided by the present invention is given below.
Test 1: skin irritation test
Test samples: skin care products prepared by the sample preparation examples using the anti-aging compositions containing examples 1 to 5.
The test method comprises the following steps: 30 healthy volunteers are selected, the age is 18-40 years, the test subjects meet the volunteer selection standard, no history of allergic dermatitis exists, and no irritant product is used in the previous month.
Taking about 0.020-0.025 ml of a test sample, coating the test sample in a small chamber of a spot tester (Beijing science popularization instrument factory), applying a special adhesive tape for external application on the back of a testee, removing the spot tester after 24 hours, slightly wiping off the residual sample by using a wet paper towel respectively at 0.5 hour, 24 hours and 48 hours, and recording the result according to the skin reaction grading standard in the technical Specification for cosmetic safety (2015). The identification criteria are shown in Table 2 and the results are shown in Table 3.
TABLE 2 table of identification standards
| Grade | Identification criteria |
| 0 | Has no irritation and erythema |
| 1 | Mild erythema |
| 2 | Erythema |
| 3 | Erythema, pimples, blisters |
| 4 | Severe edema and bulla |
TABLE 3 skin reaction results recording Table
As can be seen from the results of the closed patch test, 30 subjects showed no adverse reactions and no symptoms such as erythema, burning sensation, pruritus and the like in the anti-aging compositions prepared in examples 1 to 5 at 0.5 hour, 24 hours and 48 hours. The composition of the invention is safe and mild to use and has no stimulation to skin.
And (3) testing 2: oxidation resistance test
This test was conducted to examine the radical scavenging ability of the skin care compositions of examples 1 to 5 and comparative examples 1 to 3 prepared by the sample preparation example.
The test method comprises the following steps:
1) preparing 0.1mmol/L DPPH solution with anhydrous ethanol (1mg DPPH dissolved in 24ml anhydrous ethanol), performing ultrasonic treatment for 5min, shaking thoroughly, mixing well, storing in dark, and using up within 5 h.
2) Adding 2mL of test sample solution (the sample is dissolved by absolute ethyl alcohol) and 2mL of LDPPH solution into the same test tube, shaking uniformly, standing at room temperature in the dark for 30min, and then measuring absorbance Asample, and simultaneously measuring absorbance A0 after the 2mL of LDPPH solution and 2mL of solvent are mixed.
3) Representation of radical scavenging capacity: percent DPPH clearance (a0-Asample)/a0 x 100. A0 is the absorbance at 520nm of DPPH without sample; asample is the absorbance at 520nm of DPPH added to the sample. The test results are shown in Table 4.
TABLE 4 antioxidant test results for anti-aging compositions
From the experimental results of table 4, it can be seen that the above compositions all have a certain degree of antioxidant effect, while the compositions of the present invention in examples 1-5 have significantly more advantageous antioxidant effect than in comparative examples 1-3, wherein the effect of example 5 is the best. The results show that the composition has obvious antioxidant effect, can resist the damage of free radicals to the skin, and achieves better anti-aging effect.
And (3) testing: human body anti-aging efficacy test
In order to evaluate the anti-aging function of the composition on the skin, the invention also evaluates the overall anti-aging efficacy of the composition through the moisture content of the skin stratum corneum, the length of skin wrinkles, the skin firmness and the skin glossiness, and the used sample is the anti-aging composition prepared by the sample preparation example in the example 5.
The test method comprises the following steps: 30 volunteers of 25-50 years old are selected and tested under the relatively stable environmental condition that the temperature is 20-22 ℃ and the humidity is 40-60%. A proper amount of samples are taken and applied on the face, the samples are used for 1 time in the morning and at night every day, products or preparations with the same efficacy types are forbidden to be used on the tested parts, the test period is 0 day, 14 days and 28 days, before the test, a subject firstly cleans the face uniformly, the rest is carried out for 30min in a constant temperature and humidity room, and the data acquisition of the face is carried out by using various devices.
Water content of skin stratum corneum: the moisture content of the horny layer of the face skin is tested by a skin moisture content test probe Corneometer (Courage & Khazaka, Germany), the numerical unit is a.u., the moisture content is measured for 3 times, and the average value is taken, wherein the higher the value is, the better the value is, the moisture content of the horny layer of the face skin is represented to be high, and the moisture content test probe is mainly used for judging the moisturizing effect of the product on the skin.
Skin wrinkle length: images before and after use are photographed by an Antera3D facial image analyzer Miravex Limited (Ireland), wrinkle parameters are analyzed through image comparison, a wrinkle length value is obtained, a numerical unit is mm, the smaller the wrinkle parameter is, the lighter the wrinkle is, and the wrinkle effect of the product on skin is mainly judged.
Skin firmness: the skin compactness is measured through a skin compactness inspection probe cutometer (Courage & Khazaka, Germany), 10 cycles are measured each time, an average value is taken, the compactness F4 parameter represents the resilience speed of the skin, the faster the better the resilience speed is, the smaller the numerical value is, the better the resilience speed is, the more compact the skin is, and the skin compactness is mainly used for judging the skin compactness effect of the product.
Skin glossiness: skin gloss was measured by a skin gloss test probe GlossimeterGL 200(Courage & Khazaka, Germany) in a.u. for 3 measurements, with an average value indicating that the higher the number the better the skin is, the glossier the skin, and was used primarily to evaluate the effect of the product on improving skin gloss.
The specific statistical results of the test parameters are shown in table 5, the statistical analysis software of the data is SPSS, the data improvement value normal distribution significance test is carried out by adopting Shapiro-WilkTest, and if Sig (on both sides) > 0.01, the data are normally distributed, and the pairing t test is carried out. (bilateral) < 0.01, the distribution is abnormal, and Wilcoxon test is performed.
TABLE 5 descriptive statistical results table for each test index
After 28 days of use compared to before use: the water content of the skin stratum corneum is increased by 30.69%, and the significance is realized, so that the test sample has the effect of improving the water content of the skin; the skin wrinkle length value is reduced by 43.59%, and the significance is realized, so that the test sample has the wrinkle lightening effect; 50.05% reduction in skin firmness F4, with significance, suggests that the test sample has an effect of improving skin firmness; the skin glossiness increased by 7.69%, and was significant, suggesting that the test sample had the effect of improving skin glossiness.
In conclusion, the skin care product containing the anti-aging composition has the advantages that the skin is improved in all aspects, the moisture content of the stratum corneum of the skin is increased, the wrinkle length is reduced, the firmness F4 is reduced, the skin glossiness is improved, and the anti-aging effect on the skin is obvious. The results are schematically shown in FIG. 1.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (10)
1. An anti-aging composition is characterized by comprising plant extracts and basic components, wherein the plant extracts account for 3.3-34% of the total mass of the composition according to the mass percentage, the basic components account for 66-96.7% of the total mass of the composition, the plant extracts comprise bistort rhizome extracts, pea extracts and citrus peel extracts, and the basic components comprise solvents, preservatives and thickening agents.
2. The anti-aging composition as claimed in claim 1, wherein the weight ratio of the bistort rhizome extract, the pea extract and the citrus peel extract is (5-30): (1-5): (10-50).
3. The anti-aging composition as claimed in claim 2, wherein the weight ratio of the bistort rhizome extract, the pea extract and the citrus peel extract is (10-20): (3-5): (20-40).
4. The anti-aging composition according to claim 1, wherein the solvent is one or more of water, butylene glycol, propylene glycol, glycerol, pentanediol and hexanediol, the preservative is one or more of propylene glycol, butylene glycol, pentanediol, hexanediol, capryl glycol, ethylhexyl glycerol, p-hydroxyacetophenone, caprylyl hydroxamic acid, phenoxyethanol, potassium sorbate, sodium benzoate and other commercially available preservatives or preservative aids, and the thickener is one or more of sodium acrylate copolymer, lecithin, hydrogenated lecithin, polyacrylate cross-linked polymer-6, carbomer sodium, sodium polyacryl dimethyl taurate, ammonium acryloyl dimethyl taurate/VP copolymer and xanthan gum.
5. The anti-aging composition as claimed in claim 4, wherein the base component comprises water, hexylene glycol, caprylyl glycol, sodium acrylate copolymer, and lecithin.
6. The anti-aging composition according to claim 5, wherein the hexanediol accounts for 0.5-5% of the total mass of the base component, the caprylyl glycol accounts for 0.05-0.5% of the total mass of the base component, the sodium acrylate copolymer accounts for 0.4-0.8% of the total mass of the base component, the lecithin accounts for 0.1-0.5% of the total mass of the base component, and the water accounts for 93.2-98.95% of the total mass of the base component.
7. A process for the preparation of an anti-ageing composition according to any one of claims 1 to 6, comprising the steps of:
step one, adding acrylic acid (ester) copolymer sodium and lecithin into deionized water, soaking for 30-60min, and fully swelling to obtain a solution a for later use;
step two, adding the pea extract into deionized water which is about 10 times of the weight of the pea extract, stirring and dissolving the pea extract at room temperature, adding the pea extract into the solution a, heating the solution to 70-80 ℃, homogenizing the solution for 3-5min under the condition of 15-35 Hz, and stirring the solution for 10-20 min under the condition of 150-500 rpm until the solution is uniformly dispersed;
step three, cooling to 45-55 ℃, adding the bistort rhizome extract under stirring, and continuing stirring for 3-5min until the bistort rhizome extract is uniformly dispersed;
and step four, cooling to below 45 ℃, sequentially adding the mixed solution of the citrus peel extract, the hexanediol and the caprylyl glycol, uniformly stirring, and cooling to room temperature to obtain the composition.
8. Use of an anti-ageing composition according to any one of claims 1 to 6, in a cosmetic product.
9. The cosmetic according to claim 7, wherein the cosmetic is a skin external preparation prepared by taking the anti-aging composition as an active component and adding pharmaceutical or cosmetic conventional auxiliary materials or auxiliary components.
10. The cosmetic according to claim 7, wherein the anti-aging cosmetic is one or more of astringent, essence, lotion, cream and mask.
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| CN115590797A (en) * | 2022-10-19 | 2023-01-13 | 广东柏俐臣生物科技有限公司（Cn） | Firming and anti-wrinkle face cream containing bistort rhizome extract and preparation method thereof |
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| CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
| CN110585048A (en) * | 2019-09-29 | 2019-12-20 | 花安堂生物科技集团有限公司 | Composition with anti-saccharification and anti-oxidation functions and application thereof |
| CN112156048A (en) * | 2020-10-27 | 2021-01-01 | 浙江她创美容科技有限公司 | Natural whitening face cleaning powder and preparation method thereof |
| CN112603849A (en) * | 2021-01-04 | 2021-04-06 | 广州瑞誉化工科技有限公司 | Anti-aging composition, essence and preparation method thereof |
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| CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
| CN110585048A (en) * | 2019-09-29 | 2019-12-20 | 花安堂生物科技集团有限公司 | Composition with anti-saccharification and anti-oxidation functions and application thereof |
| CN112156048A (en) * | 2020-10-27 | 2021-01-01 | 浙江她创美容科技有限公司 | Natural whitening face cleaning powder and preparation method thereof |
| CN112603849A (en) * | 2021-01-04 | 2021-04-06 | 广州瑞誉化工科技有限公司 | Anti-aging composition, essence and preparation method thereof |
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| CN115590797A (en) * | 2022-10-19 | 2023-01-13 | 广东柏俐臣生物科技有限公司（Cn） | Firming and anti-wrinkle face cream containing bistort rhizome extract and preparation method thereof |
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