CN114177250B - Production process of stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae - Google Patents
Production process of stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae Download PDFInfo
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Abstract
The invention discloses a production process of decoction pieces for removing blood stasis and reducing phlegm based on calcined concha arcae, belonging to the technical field of traditional Chinese medicine decoction pieces, wherein the calcined concha arcae is a monarch drug, is calcined and quenched by adopting an acetic acid solution and then is easily ground into powder, and the calcined concha arcae powder is more exquisite and is convenient to disperse after ball milling; the Ganoderma extract in the dry extract powder contains ganoderan, and has anticancer effect and can prevent inflammatory cell diseases; rhizoma gastrodiae has the effect of clearing and activating the channels and collaterals, dried orange peel has the effects of regulating qi, tonifying spleen, eliminating dampness and reducing phlegm, and the dried orange peel has fragrance, so that the decoction pieces are more tasty; the concentrated solution of fructus Eriobotryae has effects of moistening lung and relieving cough, and semen Armeniacae amarum also has effects of relieving cough and asthma; the liquorice has the effects of eliminating phlegm and relieving cough and harmonizing the medicines, the fried gardenia has the effects of cooling blood and detoxifying, reducing swelling and the like, the viscosity of the prepared honey refined medicinal powder is increased after the liquorice and the fried gardenia are further fried through refined honey, the disintegration time can be increased after the liquorice and the fried gardenia are pressed into tablets, and the action time of the medicine is prolonged.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine decoction pieces, and particularly relates to a production process of stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae.
Background
The Concha arcae is shell of Arca subcrenata, arca granosa or Arca inflata Reeve of Arca. The other names of the clam shells, the clams, the ridges and the like have the efficacies of eliminating phlegm and removing blood stasis, softening hardness and dissipating stagnation, and making acid and relieving pain. Unprocessed, calcined or quenched in powder clinically.
In the aspect of removing blood stasis and reducing phlegm, patients generally need to grind calcined concha arcae into fine powder and mix with other medicines for decoction, and the decoction is taken, so that the medicine is inconvenient to take, the throat is difficult to swallow, and the medicine effect is not like western medicines. Therefore, the calcined concha arcae decoction pieces which enhance the drug effect and are convenient to take are needed.
Disclosure of Invention
The invention aims to provide a production process of a decoction piece for removing blood stasis and reducing phlegm based on calcined concha arcae, and aims to solve the problems in the background art.
The purpose of the invention can be realized by the following technical scheme: a production process of stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae comprises the following steps:
the method comprises the following steps: cleaning Concha arcae, drying, grinding, adding salt, mixing, calcining at 800-900 deg.C for 1.5-2h, and quenching Concha arcae with 8% acetic acid solution to obtain Concha arcae; primarily twisting calcined concha arcae by using a roller press, then transferring to a ball mill for continuous grinding, and sieving by using a sieve of 90-100 meshes to obtain calcined concha arcae powder; the dosage ratio of the corrugated seeds, the table salt and the acetic acid solution is 10kg:100-110g:40-50mL;
step two: mixing Ganoderma, rhizoma Gastrodiae and pericarpium Citri Tangerinae, pulverizing with a pulverizer, sieving with 60-70 mesh sieve, adding 10 times of water, extracting for 3 times, filtering, mixing filtrates, concentrating the filtrate, drying, pulverizing with a pulverizer, sieving with 100-120 mesh sieve to obtain dry extract powder, and mixing the dry extract powder and Concha arcae powder to obtain dry powder; the dosage ratio of the lucid ganoderma, the gastrodia elata and the dried orange peel is 50g:85-110g:100-120g; the dosage ratio of the dry paste powder to the calcined concha arcae powder is 20g:55-58g;
step three: adding 0.2-0.5 times volume of boiling water into refined honey, keeping warm, heating for 10-15min, stirring, adding parched fructus Gardeniae and Glycyrrhrizae radix, stirring for 20-30min to coat the surface of parched fructus Gardeniae and Glycyrrhrizae radix with refined honey; continuously parching at 50-60 deg.C until the refined honey on the surface of parched fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with pulverizer, and sieving with 100-120 mesh sieve to obtain honey-refined medicinal powder; the dosage ratio of the refined honey to the fried gardenia to the liquorice is 15mL:35g:40g of the total weight of the mixture;
step four: selecting fresh ripe loquat fruits, soaking in 5-10% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 95-100 deg.C to 0.3 times volume to obtain concentrated loquat liquid;
step five: pulverizing semen Armeniacae amarum with a pulverizer, and sieving with 60-70 mesh sieve to obtain semen Armeniacae amarum powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times (each for 2 hr), filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
step six: uniformly stirring the concentrated loquat solution and the almond extract, concentrating the mixture into thick paste at the temperature of 45-50 ℃, mixing the thick paste, the dry powder and the honey-refined medicinal powder, and pressing the mixture into tablets to obtain the stasis-removing and phlegm-reducing decoction pieces based on the calcined concha arcae; the dosage ratio of the loquat concentrated solution to the almond extracting solution is 100mL:35-50mL; the dosage ratio of the thick paste, the dry powder and the honey-refined medicinal powder is 80g:10-15g:10 g;
further, in the process of tabletting the thick paste, the dry powder and the honey refined medicinal powder in the sixth step, firstly, stirring and mixing the dry powder and the honey refined medicinal powder to obtain mixed medicinal powder, paving a layer of mixed medicinal powder on a conveyor belt, then paving a layer of thick paste, sequentially stacking, transferring the paved and stacked mixed medicinal powder and thick paste into a mixer through the conveyor belt, stirring and mixing until the thick paste and the mixed medicinal powder are not observed and the mixture does not adhere to the inner wall of the mixer, and pressing the mixture into tablets by using a tablet press; controlling the thickness of each layer of thick paste to be 3-5mm, and the thickness of each layer of mixed medicinal powder to be 2-3mm.
The invention has the beneficial effects that:
the production process of the invention prepares the stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae into tablets, wherein the calcined concha arcae is a monarch drug, is calcined and quenched by adopting an acetic acid solution and then is easy to grind into powder, and the calcined concha arcae powder is more exquisite and convenient to disperse after ball milling; the Ganoderma extract in the dry extract powder contains Ganoderma polysaccharides, and has anticancer effect and can prevent inflammatory cell pathological changes; rhizoma gastrodiae has the efficacy of clearing and activating the channels and collaterals, dried orange peel has the efficacy of regulating qi and strengthening spleen, and eliminating dampness and phlegm, and the dried orange peel has fragrance, so that the decoction pieces are more palatable; the concentrated loquat liquid has the efficacy of moistening lung to arrest cough, and the almond also has the efficacy of arresting cough and relieving asthma; the liquorice has the effects of eliminating phlegm and relieving cough and harmonizing the medicines, the fried gardenia has the effects of cooling blood and detoxifying, reducing swelling and the like, the viscosity of the prepared honey refined medicinal powder is increased after the liquorice and the fried gardenia are further fried through refined honey, the disintegration time can be increased after the liquorice and the fried gardenia are pressed into tablets, and the action time of the medicine is prolonged. The decoction pieces for removing blood stasis and eliminating phlegm based on calcined concha arcae are convenient to take compared with the traditional calcined concha arcae decoction pieces, and have good drug effect through the compatibility of traditional Chinese medicines.
Drawings
The invention is further described below with reference to the accompanying drawings.
Fig. 1 is a flow chart of the production process of the stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Preparing dry powder, comprising the following steps:
cleaning 100kg of concha arcae, drying, grinding, adding 1kg of salt, uniformly mixing, calcining at 800 ℃ for 1.5h, and calcining and quenching the concha arcae with 400mL of acetic acid solution with the mass fraction of 8% to obtain calcined concha arcae; primarily twisting calcined concha arcae by using a roller press, then transferring to a ball mill for continuous grinding, and sieving by using a 90-mesh sieve to obtain calcined concha arcae powder;
mixing 5kg of lucid ganoderma, 8.5kg of gastrodia elata and 10kg of dried orange peel, crushing by using a crusher, sieving by using a 60-mesh sieve, adding 10 times of water by mass, extracting for 3 times, filtering, combining filtrates, concentrating and drying the filtrate, crushing by using the crusher, sieving by using a 100-mesh sieve to obtain dry extract powder, and mixing 200g of the dry extract powder and 550g of calcined concha arcae powder to obtain dry powder.
Example 2
Preparing dry powder, comprising the following steps:
cleaning 100kg of concha arcae, drying, grinding, adding 1.1kg of salt, uniformly mixing, calcining at 900 ℃ for 2h, and calcining and quenching the concha arcae with 500mL of acetic acid solution with the mass fraction of 8% to obtain calcined concha arcae; primarily twisting calcined concha arcae by using a roller press, transferring to a ball mill for continuous grinding, and sieving by using a 100-mesh sieve to obtain calcined concha arcae powder;
mixing 5kg of lucid ganoderma, 11kg of gastrodia elata and 12kg of dried orange peel, crushing by using a crusher, sieving by using a 70-mesh sieve, adding 10 times of water by mass, extracting for 3 times, filtering, combining filtrates, concentrating and drying the filtrate, crushing by using the crusher, sieving by using a 120-mesh sieve to obtain dry extract powder, and mixing 200g of the dry extract powder and 580g of calcined concha arcae powder to obtain dry powder.
Example 3
The preparation method of the honey-refined medicinal powder comprises the following steps:
adding 200mL of boiling water into 1.5L of refined honey, heating for 10min while stirring, adding 3.5kg of parched fructus Gardeniae and 4kg of Glycyrrhrizae radix, stirring for 20min to coat the surface of parched fructus Gardeniae and Glycyrrhrizae radix with refined honey; continuously frying at 50 deg.C until the refined honey on the surface of fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with pulverizer, and sieving with 100 mesh sieve to obtain honey refined medicinal powder.
Example 4
The preparation method of the honey-refined medicinal powder comprises the following steps:
adding 750mL of boiling water into 1.5L of refined honey, continuously heating for 15min while continuously stirring, adding 3.5kg of fried fructus Gardeniae and 4kg of Glycyrrhrizae radix, and continuously stirring for 30min to coat the surfaces of the fried fructus Gardeniae and Glycyrrhrizae radix with refined honey; continuously frying at 60 deg.C until the refined honey on the surface of parched fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with a pulverizer, and sieving with 120 mesh sieve to obtain honey refined medicinal powder.
Example 5
Preparing thick paste, comprising the following steps:
selecting fresh ripe loquat fruits, soaking in 5% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 95 ℃ to 0.3 times of volume to obtain concentrated loquat liquid;
crushing the almond by a crusher and sieving the almond by a 60-mesh sieve to obtain almond powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times (each for 2 hr), filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
mixing 10L of loquat concentrated solution and 3.5L of almond extract, stirring, and concentrating at 45 deg.C to obtain soft extract.
Example 6
Preparing thick paste, comprising the following steps:
selecting fresh ripe loquat fruits, soaking in 10% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 100 deg.C to 0.3 times volume to obtain concentrated loquat liquid;
crushing the almonds by a crusher and sieving the crushed almonds by a 70-mesh sieve to obtain almond powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times, each for 2 hr, filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
mixing 10L of loquat concentrated solution and 5L of almond extract, stirring, and concentrating at 50 deg.C to obtain soft extract.
Example 7
Referring to fig. 1, the preparation of decoction pieces for removing blood stasis and resolving phlegm based on calcined concha arcae comprises the following steps:
the method comprises the following steps: cleaning 100kg of concha arcae, drying, grinding, adding 1kg of salt, mixing uniformly, calcining at 850 ℃ for 1.8h, and calcining and quenching the concha arcae with 450mL of acetic acid solution with the mass fraction of 8% to obtain calcined concha arcae; primarily twisting calcined concha arcae by using a roller press, transferring to a ball mill for continuous grinding, and sieving by using a 100-mesh sieve to obtain calcined concha arcae powder;
mixing 5kg of lucid ganoderma, 9.5kg of gastrodia elata and 11kg of dried orange peel, crushing by using a crusher, sieving by using a 70-mesh sieve, adding water with the mass being 10 times that of the lucid ganoderma for 3 times, filtering, combining filtrates, concentrating and drying the filtrate, crushing by using a crusher, sieving by using a 120-mesh sieve to obtain dry paste powder, and mixing 200g of the dry paste powder and 560g of calcined concha arcae powder to obtain dry powder.
Step two: adding 500mL of boiling water into 1.5L of refined honey, continuously heating for 12min and continuously stirring, adding 3.5kg of fried gardenia and 4kg of liquorice, continuously stirring for 25min, and wrapping the surfaces of the fried gardenia and the liquorice with the refined honey; continuously frying at 55 deg.C until the refined honey on the surface of fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with pulverizer, and sieving with 110 mesh sieve to obtain refined honey powder.
Step three: selecting fresh ripe loquat fruits, soaking in 8% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 98 deg.C to 0.3 times volume to obtain concentrated loquat liquid;
crushing the almonds by a crusher and sieving the crushed almonds by a 70-mesh sieve to obtain almond powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times, each for 2 hr, filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
mixing 10L of loquat concentrated solution and 4L of almond extract, stirring, and concentrating at 48 deg.C to obtain soft extract.
Step four: preparing 8kg of thick paste, stirring and mixing 1g of dry powder and 1kg of honey-refined medicinal powder to obtain mixed medicinal powder, paving a layer of mixed medicinal powder with the thickness of 2mm on a conveyor belt, paving a layer of thick paste with the thickness of 3mm, sequentially stacking, transferring the paved and stacked mixed medicinal powder and thick paste into a mixer through the conveyor belt, stirring and mixing until the thick paste and the mixed medicinal powder cannot be observed and the mixture does not adhere to the inner wall of the mixer, and pressing the mixture into tablets by using a tablet press to obtain the stasis-removing and phlegm-reducing decoction pieces based on the calcined concha arcae.
Example 8
Referring to fig. 1, the preparation of decoction pieces for removing blood stasis and resolving phlegm based on calcined concha arcae comprises the following steps:
the method comprises the following steps: cleaning 100kg of concha arcae, drying, grinding, adding 1kg of salt, mixing uniformly, calcining at 850 ℃ for 1.8h, and calcining and quenching the concha arcae with 450mL of acetic acid solution with the mass fraction of 8% to obtain calcined concha arcae; primarily twisting calcined concha arcae by using a roller press, transferring to a ball mill for continuous grinding, and sieving by using a 100-mesh sieve to obtain calcined concha arcae powder;
mixing 5kg of lucid ganoderma, 9.5kg of gastrodia elata and 11kg of dried orange peel, crushing by using a crusher, sieving by using a 70-mesh sieve, adding 10 times of water by mass, extracting for 3 times, filtering, combining filtrates, concentrating and drying the filtrate, crushing by using the crusher, sieving by using a 120-mesh sieve to obtain dry extract powder, and mixing 200g of the dry extract powder and 560g of calcined concha arcae powder to obtain dry powder.
Step two: adding 500mL of boiling water into 1.5L of refined honey, continuously heating for 12min and continuously stirring, adding 3.5kg of fried gardenia and 4kg of liquorice, continuously stirring for 25min, and wrapping the surfaces of the fried gardenia and the liquorice with the refined honey; continuously frying at 55 deg.C until the refined honey on the surface of fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with pulverizer, and sieving with 110 mesh sieve to obtain refined honey powder.
Step three: selecting fresh ripe loquat fruits, soaking in 8% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 98 deg.C to 0.3 times volume to obtain concentrated loquat liquid;
crushing the almonds by a crusher and sieving the crushed almonds by a 70-mesh sieve to obtain almond powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times (each for 2 hr), filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
mixing 10L of loquat concentrated solution and 4L of almond extract, stirring, and concentrating at 48 deg.C to obtain soft extract.
Step four: preparing 8kg of thick paste, stirring and mixing 1.2g of dry powder and 1.8kg of honey-refined medicinal powder to obtain mixed medicinal powder, paving a layer of mixed medicinal powder with the thickness of 3mm on a conveyor belt, paving a layer of thick paste with the thickness of 4mm, stacking in sequence, transferring the paved and stacked mixed medicinal powder and the thick paste into a mixer through the conveyor belt, stirring and mixing until the thick paste and the mixed medicinal powder cannot be observed and the mixture does not adhere to the inner wall of the mixer, and pressing the mixture into tablets by using a tablet press to obtain the stasis-removing and phlegm-reducing decoction pieces based on the calcined concha arcae.
Example 9
Referring to fig. 1, the preparation of decoction pieces for removing blood stasis and resolving phlegm based on calcined concha arcae comprises the following steps:
the method comprises the following steps: cleaning 100kg of concha arcae, drying, grinding, adding 1kg of salt, mixing uniformly, calcining at 850 ℃ for 1.8h, and calcining and quenching the concha arcae with 450mL of acetic acid solution with the mass fraction of 8% to obtain calcined concha arcae; primarily twisting calcined concha arcae by using a roller press, transferring to a ball mill for continuous grinding, and sieving by using a 100-mesh sieve to obtain calcined concha arcae powder;
mixing 5kg of lucid ganoderma, 9.5kg of gastrodia elata and 11kg of dried orange peel, crushing by using a crusher, sieving by using a 70-mesh sieve, adding 10 times of water by mass, extracting for 3 times, filtering, combining filtrates, concentrating and drying the filtrate, crushing by using the crusher, sieving by using a 120-mesh sieve to obtain dry extract powder, and mixing 200g of the dry extract powder and 560g of calcined concha arcae powder to obtain dry powder.
Step two: adding 500mL of boiling water into 1.5L of refined honey, continuously heating for 12min while stirring, adding 3.5kg of fried fructus Gardeniae and 4kg of Glycyrrhrizae radix, and continuously stirring for 25min to coat the surfaces of the fried fructus Gardeniae and Glycyrrhrizae radix with refined honey; continuously frying at 55 deg.C until the refined honey on the surface of fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing with pulverizer, and sieving with 110 mesh sieve to obtain honey refined medicinal powder.
Step three: selecting fresh ripe loquat fruits, soaking in 8% saline water for 30min, cleaning with clear water, removing peel and kernel, mincing loquat pulp, filtering with a filter press, taking filtrate, and concentrating the filtrate at 98 deg.C to 0.3 times volume to obtain concentrated loquat liquid;
crushing the almonds by a crusher and sieving the crushed almonds by a 70-mesh sieve to obtain almond powder; extracting semen Armeniacae amarum powder with 80% ethanol solution under reflux for 3 times (each for 2 hr), filtering and mixing extractive solutions, and concentrating the extractive solution to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
mixing 10L of loquat concentrated solution and 4L of almond extractive solution, stirring, and concentrating at 48 deg.C to obtain soft extract.
Step four: preparing 8kg of thick paste, stirring and mixing 1.5g of dry powder and 2kg of honey-refined medicinal powder to obtain mixed medicinal powder, laying a layer of mixed medicinal powder with the thickness of 3mm on a conveyor belt, then laying a layer of thick paste with the thickness of 5mm, stacking the thick pastes in sequence, transferring the laid and stacked mixed medicinal powder and the thick paste into a mixer through the conveyor belt, stirring and mixing until the thick paste and the mixed medicinal powder cannot be observed and the mixture does not adhere to the inner wall of the mixer, and pressing the mixture into tablets by using a tablet press to obtain the stasis-removing and phlegm-reducing decoction pieces based on the calcined concha arcae.
Examples 7-9 were tested as follows:
selecting 60 rats with similar growth conditions and same health conditions, and randomly dividing the rats into 4 groups: the normal group, the model group, the drink group and the western medicine group are four groups, and each group is not less than 10.
Except the normal group, the other three groups are sensitized by injecting the mixture of OVA (ovalbumin) and aluminum hydroxide into the abdominal cavity and are subjected to atomization excitation to replicate the asthma model. 1mL of 100mgOVA +100mg aluminum hydroxide mixed solution is given on the 1 st and 8 th days of feeding to sensitize rats; starting on day 15, ova nebulization was initiated at 1% for 30min each, 1 time every other day, for a total of 7 times. In the molding process, the rat has the symptoms of scratching facial fur, restlessness, intermittent cough, nasal discharge, purple dark lips, rapid respiration, wheezing and the like, and the molding is successful.
Starting grouping treatment on 7 days after the model building, and continuing for 2 weeks; now, the stasis-removing and phlegm-reducing decoction pieces based on calcined concha arcae in the embodiment 8 are dissolved by water with the mass 30 times that of the decoction pieces, rats in a tablet group are subjected to intragastric administration according to the amount of 3mL decoction piece solution per day twice a day, a western medicine group is subjected to intragastric administration and 0.01% budesonide atomization inhalation for 20min, and a normal group and a model group are subjected to 3mL of normal saline for 2 times a day.
After the treatment, the left lung of the rat is cut off, the size of the lower margin tissue of the left lung is 0.5cm multiplied by 0.5cm after rinsing with a phosphate-hydrochloric acid buffer solution, and the left lung is fixed in a 4% paraformaldehyde solution for slicing and HE staining. The infiltration of inflammatory cells and the secretion of bronchial mucus in the bronchi and around the alveoli of each group of rats were observed under a 200-fold optical microscope. The results are shown in table 1:
TABLE 1
As can be seen from table 1, under the same feeding condition, with different treatment means, the decoction piece group adopts the stasis removing and phlegm eliminating decoction pieces based on the calcined concha arcae obtained in example 8 for treatment, the treatment effect is similar to that of the western medicine group, and the stasis removing and phlegm eliminating decoction pieces based on the calcined concha arcae in example 8 has a good phlegm eliminating effect by comparing with the healthy rats in the normal group and the sick rats in the model group.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (3)
1. A production process of stasis-removing phlegm-reducing decoction pieces based on calcined concha arcae is characterized by comprising the following steps:
the method comprises the following steps: grinding Concha arcae, mixing with salt, calcining at 800-900 deg.C for 1.5-2 hr, quenching with acetic acid solution to obtain Concha arcae, grinding, and sieving with 90-100 mesh sieve to obtain Concha arcae powder;
step two: pulverizing Ganoderma, rhizoma Gastrodiae and pericarpium Citri Tangerinae, sieving with 60-70 mesh sieve, extracting with water for 3 times, filtering, mixing filtrates, concentrating, drying, pulverizing, sieving with 100-120 mesh sieve to obtain dry extract powder, and mixing the dry extract powder and Concha arcae powder to obtain dry powder;
step three: mixing the concentrated solution of fructus Eriobotryae and the extractive solution of semen Armeniacae amarum, concentrating to obtain soft extract, mixing the soft extract, dry powder and Mel powder, and tabletting to obtain decoction pieces for removing blood stasis and eliminating phlegm based on Concha arcae;
in the second step, the dosage ratio of the lucid ganoderma, the gastrodia elata and the dried orange peel is 50g:85-110g:100-120g; the dosage ratio of the dry paste powder to the calcined concha arcae powder is 20g:55-58g;
the concentrated solution of loquat in the third step is prepared by the following steps:
soaking fructus Eriobotryae in saline water for 30min, washing with water, mincing fructus Eriobotryae, press filtering, and concentrating filtrate at 95-100 deg.C to 0.3 times volume to obtain concentrated solution;
the almond extracting solution in the third step is prepared by the following steps:
pulverizing semen Armeniacae amarum, sieving with 60-70 mesh sieve, reflux-extracting with 80% ethanol solution for 3 times (2 hr each time), filtering, mixing extractive solutions, and concentrating to 0.3 times of original volume to obtain semen Armeniacae amarum extractive solution;
the honey refining medicinal powder in the third step is prepared by the following steps:
adding 0.2-0.5 times volume of boiling water into refined honey, keeping the temperature for 10-15min, adding parched fructus Gardeniae and Glycyrrhrizae radix, stirring for 20-30min, parching until the refined honey on the surface of fructus Gardeniae and Glycyrrhrizae radix is dried, pulverizing, and sieving with 100-120 mesh sieve to obtain honey refined medicinal powder; the frying temperature is 50-60 deg.C; the dosage ratio of the refined honey to the fried gardenia to the liquorice is 15mL:35g:40g.
2. The production process of the decoction pieces for removing blood stasis and reducing phlegm based on the calcined concha arcae as claimed in claim 1, wherein the mixing and tabletting in the third step are as follows:
mixing the dry powder and the honey-refined powder under stirring to obtain mixed powder, spreading a layer of thick paste, stacking in sequence, mixing the spread and stacked mixed powder and thick paste under stirring to obtain a mixture, and pressing the mixture into tablets; the thickness of each layer of thick paste is 3-5mm, and the thickness of each layer of mixed medicinal powder is 2-3mm.
3. The production process of the decoction pieces for removing blood stasis and eliminating phlegm based on calcined concha arcae as claimed in claim 1, wherein the ratio of the concentrated solution of loquat and the extracted solution of apricot kernel in the three steps is 100mL:35-50mL; the dosage ratio of the thick paste, the dry powder and the honey-refined medicinal powder is 80g:10-15g:10 g of.
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