CN114010559A

CN114010559A - Moisturizing composition and preparation method thereof

Info

Publication number: CN114010559A
Application number: CN202111366664.6A
Authority: CN
Inventors: 李菊兰; 苏晋峰; 曹冬妮; 邓伟健; 刘立侠; 陈嘉欣
Original assignee: Youyan Dermatology Research Guangzhou Co ltd
Current assignee: Youyan Dermatology Research Guangzhou Co ltd
Priority date: 2021-11-17
Filing date: 2021-11-17
Publication date: 2022-02-08
Anticipated expiration: 2041-11-17
Also published as: CN114010559B

Abstract

The invention provides a moisturizing composition and a preparation method thereof, and belongs to the technical field of cosmetics. The product is compounded by combining a plurality of plant extracts and high-efficiency moisturizing components, and the components have synergistic interaction, so that the obtained product has high-efficiency long-term deep moisturizing effect, provides more natural moisturizing factors for the skin, promotes and maintains the hydration and moisture content of the surface layer, the middle layer and the deep layer of the skin, can ensure the property stability during use and storage under a system of zero preservative, does not irritate the skin of a user, and has high safety and good use experience. The invention also provides a preparation method of the moisturizing and moisturizing composition and application of the moisturizing and moisturizing composition in preparation of moisturizing skin care products.

Description

Moisturizing composition and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a moisturizing composition and a preparation method thereof.

Background

The skin is the largest organ of the human body, and the absorption and the dispersion of water are kept balanced through microcirculation all the time in the process of human body activity, so that the human body can keep constant temperature. However, when the air temperature is lowered, the skin cuticle can not adjust enough moisturizing factors in time, so that the activity of the oil glands is reduced, microcirculation is damaged, the skin moisture is seriously diffused, and the skin is tight and dry. At this time, the corresponding moisturizing skin care product is used to prevent the skin from evaporating.

However, the existing moisturizing products are generally limited to the moisturizing effect on the surface, the moisturizing effect is general, the improving effect on skin microcirculation is weak, the problem of skin dryness cannot be fundamentally improved, and the moisturizing lasting effect is poor. Meanwhile, the existing moisturizing product has more nutrient components, and is correspondingly compounded and added with an antiseptic system, so that the moisturizing product has better bacteriostatic ability, but easily causes irritation to the skin, and further has the problem of nourishing new skin.

Disclosure of Invention

Based on the defects of the prior art, the invention aims to provide the moisturizing and moisturizing composition, the product has multiple high-efficiency moisturizing components, and the components are synergistic, so that the long-acting deep moisturizing and moisturizing skin effect is realized; the product is characterized in that an additional preservative is not required to be introduced through an optimized screening system, the property is stable, the skin is not irritated, the safety is high, and the use experience is good.

In order to achieve the purpose, the invention adopts the technical scheme that:

a moisturizing and moisture-preserving composition comprises the following components in percentage by mass: 0.1-5% of xylitol mixture, 0.01-0.15% of rehmannia glutinosa ROOT EXTRACT (REHMANNIA CHINENSIS ROOT EXTRACT), 0.2-5% of natural glycan, 0.01-5% of biogum sugar GUM-1 (bioscharide GUM-1), 0.2-5% of peach (Prunus PERSICA) resin EXTRACT, 0.1-7% of althea OFFICINALIS (ALTHAEA OFFICINALIS) EXTRACT and the balance of water; the xylitol mixture comprises xylitol-based glucoside, dehydrated xylitol, xylitol and glucose; the natural glycans include saccharide isomers.

In the components of the moisturizing and moisturizing composition, the xylitol mixture contains xylitol-based glucoside and other natural saccharides, so that the synthesis of dermal hyaluronic acid in skin can be effectively promoted, and the moisture reserve of dermis can be increased; improving the cell hydration of the acanthosphere and the stratum granulosum of the epidermis of human skin, and increasing the quantity of water channel transport protein in the epidermis; in addition, the skin dryness brought by the organic solvent carrier in the product can be effectively improved, so that the product can keep long-acting moistening feeling after being used.

The radix rehmanniae extract is prepared by a special process, can be used as a component in a skin care product to endow the product with a mild but non-greasy skin feel, has a good moisturizing effect, and can promote the repair and healing of skin microcracks.

The saccharide isomerate contained in the natural polysaccharide is similar to the structure of skin, can effectively connect the skin and lock moisture, quickly recover the moisture content of a dry skin area, has a moistening effect directly reaching the deep layer of the skin, improves the elasticity of the skin, and still keeps long-acting effect without deterioration under the condition of no preservative.

The biological sugar gum-1 is a unique plant type biological fermentation polysaccharide, has excellent lubricating feeling like silicone grease when being applied to the surface of the skin, does not have sticky feeling and light reflecting feeling, and has multiple effects of moisturizing, relieving the skin and resisting skin aging and inflammation.

The peach resin extract is also called peach gum extract, because peach gum has certain moisture absorption and water replenishing effects, when the peach gum is applied to skin care products, the peach resin extract can endow the products with the effects of moisturizing, reducing skin roughness and improving skin desquamation symptoms, and meanwhile, the peach resin extract is used as a natural plant extract, so that the skin after use can obviously feel excellent natural moisture.

Althaea officinalis is also called hyaluronic acid in the plant world and is rich in uronic acid, and uronic acid is known as the best moisture-retaining component at present due to its super-strong water-carrying capacity. The marshmallow extract can rapidly supplement moisture to human skin, improve moisture retention, and effectively improve wrinkle phenomenon caused by dryness on skin surface.

The moisturizing and moisturizing composition disclosed by the invention is prepared by combining and compounding various plant extracts and high-efficiency moisturizing components, and the components are synergistic, so that the obtained product has a high-efficiency long-term deep moisturizing effect, provides more natural moisturizing factors for the skin, keeps the moisture content of the skin, can ensure the property stability during use and storage under a zero-preservative system, does not irritate the skin of a user, and is high in safety and good in use experience.

Preferably, the xylitol mixture comprises the following components in percentage by mass: 35-50% of xylitol-based glucoside, 24-34% of dehydrated xylitol, 5-15% of xylitol, 0-5% of glucose and the balance of water.

By the preferable proportion, the components in the product have more stable properties, the drying side effect of the product on the skin is reduced under the condition of not adding glycerin as a solvent, and the biological water replenishing activity of the skin is higher.

Preferably, the natural polysaccharide comprises the following components in percentage by mass: 25-50% of water, 0.1-1% of citric acid, 0.1-1% of monosodium citrate and the balance of saccharide isomers.

Through the matching of water and a stabilizer, the saccharide isomer can ensure the long-acting stability of the saccharide isomer under the condition of no preservative, and can continuously endow the skin with deep shrinkage capability.

Preferably, the moisturizing and moisture-preserving composition comprises the following components in percentage by mass: 2.8-3.2% of xylitol mixture, 0.04-0.06% of rehmannia glutinosa libosch extract, 0.8-1.2% of natural polysaccharide, 10.4-0.6% of biological carbohydrate gum, 1.8-2.2% of peach resin extract, 1.5-2.5% of marshmallow extract and the balance of water;

more preferably, the moisturizing and moisture-keeping composition comprises the following components in percentage by mass: xylitol mixture 3%, radix rehmanniae Preparata extract 0.05%, natural polysaccharide 1%, biological sugar gum-10.5%, peach resin extract 3%, flos Althaeae Roseae extract 2.5%, and water in balance

The inventor finds that the components can realize the synergistic moisturizing effect under the specific mixture ratio, and the synergistic improvement effect is better within the preferable range.

The invention also aims to provide a preparation method of the moisturizing and moisture-preserving composition, which comprises the following steps:

and adding water into the xylitol mixture, the rehmannia glutinosa extract, the natural polysaccharide, the biological carbohydrate gum-1, the peach resin extract and the marshmallow extract according to the proportion, mixing and stirring uniformly to obtain transparent liquid, thus obtaining the moisturizing and moisturizing composition.

Preferably, the stirring speed is 30-400 rpm, and the time is 5-10 min.

The preparation method of the moisturizing and moisture-preserving composition provided by the invention is simple in operation steps, and can realize industrial mass production.

The invention further aims to provide application of the moisturizing and moisturizing composition in preparation of moisturizing and skin-care products.

The invention has the beneficial effects that: the invention provides a moisturizing and moisturizing composition, which is prepared by combining and compounding multiple plant extracts and efficient moisturizing components, wherein the components are synergistic, so that the obtained product has efficient long-term deep moisturizing and moisturizing effects, provides more natural moisturizing factors for skin, promotes and maintains the hydration and moisture content of the surface layer, the middle layer and the deep layer of the skin, and can ensure the property stability during use and storage under a preservative-free system, the bacteriostatic effect is good, the skin of a user cannot be stimulated, the safety is high, and the use experience is good. The invention also provides a preparation method of the moisturizing and moisturizing composition and application of the moisturizing and moisturizing composition in preparation of moisturizing skin care products.

Detailed Description

For better illustrating the objects, technical solutions and advantages of the present invention, the present invention will be further described with reference to specific examples, which are intended to be understood in detail, but not intended to limit the present invention.

Examples 1 to 6

The formulation of the moisturizing composition in each example is shown in table 1.

The xylitol mixture comprises the following components in percentage by mass: 35-40% of xylitol-based glucoside, 24-34% of dehydrated xylitol, 5-15% of xylitol, 0.1-5% of glucose and the balance of water;

the natural polysaccharide is produced by DSM Limited in the Netherlands

The product comprises the following components in percentage by mass: 25-50% of water, 0.1-1% of citric acid, 0.1-1% of monosodium citrate and the balance of saccharide isomers;

the peach resin extract comprises the following components in percentage by mass: 45% of glycerol, 30% of water, 18% of trehalose, 10% of (pure plant extract) peach resin extract and the balance of 1, 2-hexanediol;

the marshmallow extract comprises the following components in percentage by mass: 48% of glycerin, 5% of a medicinal hollyhock extract (pure plant extract) and the balance of water;

the biological sugar gum-1 is a commercial biological sugar gum-1 product;

the rehmannia root extract is a commercially available pure rehmannia root extract product.

The preparation method of the moisturizing and moisturizing composition comprises the following steps:

and adding water into the xylitol mixture, the rehmannia glutinosa extract, the natural polysaccharide, the biological carbohydrate gum-1, the peach resin extract and the marshmallow extract according to the proportion, mixing, stirring at the speed of 30-400 rpm for 5-10 min, uniformly stirring to form transparent liquid, and discharging to obtain the moisturizing composition.

TABLE 1

Comparative examples 1 to 5

In the comparative examples of the moisturizing and moisturizing composition, the essential liquid and the products of examples 1 to 6 in each comparative example are different only in the formula, the formula is shown in table 2, and the preparation method of the product is the same as that in examples 1 to 6.

TABLE 2

Comparative example 4

The comparative example differs from example 1 only in that the xylitol mixture was replaced with hyaluronic acid at the same added content.

Comparative example 5

The present comparative example differs from example 1 only in that the natural glycan was replaced with dextran at the same added level.

Effect example 1

In order to verify the stability of the soothing and repairing essence product obtained by the invention, the products obtained in each example and comparative example are subjected to a series of stability tests:

(1) the pH of the product obtained in examples and comparative examples was measured at room temperature after dilution by mixing with water at a volume ratio of 1: 10.

(2) The products obtained in the examples and the comparative examples are subjected to heat resistance, cold resistance and cold-heat cycle tests under the following test conditions: (a) respectively preserving the heat at 48 +/-2 ℃ for 3 months, and performing physical and chemical tests after the room temperature is recovered; (b) respectively preserving heat at-15 +/-2 ℃ for 3 months, and performing physicochemical test after the room temperature is recovered; (c) and (3) respectively preserving heat for 24h at 48 ℃, normal temperature and-15 ℃ in sequence, circulating for three times according to the sequence, and performing physicochemical test after the room temperature is recovered, wherein the test method is QB/T2660. The results are shown in table 3.

TABLE 3

As can be seen from table 3, the moisturizing and moisturizing composition disclosed by the invention is weakly acidic, is a light yellow transparent liquid in appearance, does not change color or precipitate under different temperature environments, and has high stability under a system without an antiseptic; in contrast, the products obtained in comparative examples 1 to 5 have the phenomenon of precipitation or color change in different environmental tests, and have insufficient stability.

Effect example 2

In order to verify the use effect of the moisturizing and moisturizing composition, the products obtained in the examples and the comparative examples are subjected to spot-pasting test to verify whether the product has irritation to a human body and whether the product can be safely and directly used.

(1) Patch test

The test population: the number of volunteers was 330, 18-45 years old, 165 women, 165 men, and 165 men, with healthy skin and no history of skin allergy. The number of people is randomly divided into 11 groups, and the proportion of men to women in each group is 1:1, the products of the test examples and comparative examples, respectively, are in groups.

The test method comprises the following steps: the products of example 1 and comparative example 4 were subjected to patch tests according to the human skin patch test method of technical Specifications for cosmetic safety (2015 edition), and the results were recorded according to skin reaction grading standards. Wherein, the skin reaction grading standard is as follows: (-, negative reaction, grade 0); (±, suspicious reaction, only weak erythema, grade 1); (+, weak positive reaction (erythema reaction), erythema, infiltration, edema, and possibly pimples, grade 2); (++, strong positive response (herpes response), erythema, infiltration, edema, papules, herpes, response beyond the test area, grade 3); (+++, very positive reaction (confluent herpes reaction), obvious erythema, severe infiltration, edema, confluent herpes, reaction beyond the test area, grade 4).

The test results are shown in table 4.

TABLE 4

As can be seen from Table 4, the moisturizing and moisturizing composition of the present invention has no significant irritation to the skin and is comfortable to the skin after application.

(2) Skin moisturizing and hydrating conditions

According to the patch test results, the products obtained in examples and comparative examples were subjected to a moisturizing efficacy test for direct use.

The test population: 88 secondary volunteers, women of 25-45 years old, had healthy skin and no history of skin allergy. The groups were randomly divided into 11 groups of 8 persons, and the products obtained in examples and comparative examples were used in units of groups.

The test method comprises the following steps: after a subject washes the face with clean water, the corresponding test sample (1 +/-0.05 g/time) is smeared on the face for skin care and maintenance, the skin care and maintenance are respectively carried out 1 time in the morning, at noon and at night and continuously used for 4 weeks, and the subject does not use other skin care products except the test sample in the test period.

The Moisture content of the facial skin of a subject before and after use is measured, the Moisture content of the facial skin is measured by a skin Moisture measuring instrument, the test result is represented by a set Moisture Measurement Value (MMV/%), and the water supplementing and moisturizing effect of the product is detected by the change rate of the Moisture content of the skin, wherein the change rate is (Moisture content before use after use)/Moisture content before use 100 percent, and the larger the Value is, the better the water supplementing and moisturizing effect of the product is represented, and the Measurement result is shown in Table 5.

TABLE 5

As is clear from Table 5, the moisturizing compositions obtained in examples 1 to 6 all showed significant effects in which the rate of change in the moisture content of the skin was 30% or more after use.

(3) Skin gloss condition

In the test of the moisturizing effect, the Skin glossiness test probe Skin-gloss meter GL200 (german Courage + Khazaka, 50829Koln, Germany) is used to test the measured value of the tested part after the sample is used and subtract the blank control value of the tested part before the sample is used to obtain the mean value of the variation of the Skin glossiness of the tested part before and after the product is used, and the formula is calculated: g ═ N_x-N_o(ii) a Wherein: g is the skin glossiness variation; n is a radical of_xIs a measure of skin gloss 28 days after use of the product; n is a radical of_oIs a skin gloss blank measurement.

Test results were recorded as an average for each group, as shown in table 6.

TABLE 6

As can be seen from the statistical results in Table 6, corresponding to the moisturizing and hydrating effects, the skin gloss improvement effect of the products of examples 1 to 6 is better than that of the products prepared in the ratios of 1 to 5, and the gloss variation can reach 0.7.

(4) Improvement in skin elasticity

Similarly to the skin glossiness test, the skin elasticity value R2 before and after the application of the test part was measured using a skin elasticity tester (model: MPA580) of the german CK company before and after the application of the sample, and the degree of change in the skin elasticity was evaluated based on the difference between the values before and after the skin elasticity value, Δ R2 ═ R2 (after the application) R2 (before the application), and the larger the Δ R2 value, the more the elasticity was increased.

Test results were recorded as an average for each group, as shown in table 7.

TABLE 7

Test sample	△R2
		Example 1	0.312
Example 2	0.343
		Example 3	0.361
Example 4	0.381
		Example 5	0.363
Example 6	0.386
		Comparative example 1	0.162
Comparative example 2	0.136
		Comparative example 3	0.143
Comparative example 4	0.157
		Comparative example 5	0.148

As can be seen from the statistical results in Table 7, the moisturizing and moisturizing composition of the present invention also has significant effect of increasing skin elasticity after application.

(5) Feeling of use

After the test is completed, the use experience summary of experience and irritation is carried out on each volunteer, the skin feeling summary evaluation is carried out according to the skin adhesion, the moistening performance, the brightness improvement performance (glossiness improvement), the moisture retention performance and the skin elasticity, the evaluation adopts fractional evaluation (integer value scoring, 1-10 points, wherein the full score is 10 points), the average value of all the component is taken for recording, and meanwhile, the product condition of low-score single option (less than 5 points) is recorded, as shown in table 8.

TABLE 8

As can be seen from Table 8, corresponding to the above single test, the use evaluation scores of the moisturizing and moisturizing composition disclosed by the invention are higher than 9, and the moisturizing and moisturizing composition is highly evaluated by the use of volunteers, so that the skin quality can be effectively improved; in contrast, the products obtained in the comparative examples 1 to 5 have poor use experience evaluation due to improper formula.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. The moisturizing and moisturizing composition is characterized by comprising the following components in percentage by mass: 0.1-5% of xylitol mixture, 0.01-0.15% of rehmannia glutinosa libosch extract, 0.2-5% of natural polysaccharide, 10.01-5% of biological carbohydrate gum, 0.2-5% of peach resin extract, 0.1-7% of marshmallow extract and the balance of water; the xylitol mixture comprises xylitol-based glucoside, dehydrated xylitol, xylitol and glucose; the natural glycans include saccharide isomers.

2. The moisturizing and moisturizing composition of claim 1, wherein the xylitol mixture comprises the following components in percentage by mass: 35-50% of xylitol-based glucoside, 24-34% of dehydrated xylitol, 5-15% of xylitol, 0-5% of glucose and the balance of water.

3. The moisturizing and moisturizing composition of claim 1, wherein the natural polysaccharide comprises the following components in percentage by mass: 25-50% of water, 0.1-1% of citric acid, 0.1-1% of monosodium citrate and the balance of saccharide isomers.

4. The moisturizing and moisturizing composition of claim 1, comprising the following components in percentage by mass: 2.8-3.2% of xylitol mixture, 0.04-0.06% of rehmannia glutinosa libosch extract, 0.8-1.2% of natural polysaccharide, 10.4-0.6% of biological carbohydrate gum, 1.8-2.2% of peach resin extract, 1.5-2.5% of marshmallow extract and the balance of water.

5. The moisturizing and moisturizing composition of claim 4, comprising the following components in percentage by mass: 3% of xylitol mixture, 0.05% of rehmannia glutinosa libosch root extract, 1% of natural polysaccharide, 10.5% of biological carbohydrate gum, 3% of peach resin extract, 2.5% of marshmallow extract and the balance of water.

6. The method for preparing the moisturizing and moisturizing composition according to any one of claims 1 to 5, comprising the steps of:

7. The moisturizing and moisturizing composition as claimed in claim 6, wherein the stirring speed is 30 to 400rpm and the time is 5 to 10 min.

8. The moisturizing and moisturizing composition as claimed in any one of claims 1 to 5, wherein the moisturizing and moisturizing composition is used for preparing a moisturizing and skin-care product.