CN113952430B

CN113952430B - Chinese herbal medicine compound preparation for treating eczema and using method thereof

Info

Publication number: CN113952430B
Application number: CN202111499563.6A
Authority: CN
Inventors: 杨耀忠; 陈晓晖; 陈晓晔; 戈雪婧; 孙晓庭; 叶子
Original assignee: Shanghai Baoshan District Wusong Street Community Health Service Center
Current assignee: Shanghai Baoshan District Wusong Street Community Health Service Center
Priority date: 2021-12-09
Filing date: 2021-12-09
Publication date: 2022-11-11
Anticipated expiration: 2041-12-09
Also published as: CN113952430A

Abstract

The invention discloses a Chinese herbal medicine compound preparation for treating eczema, which comprises the following main components in parts by weight: 40-60 parts of radix sophorae flavescentis, 40-60 parts of golden larch bark, 40-60 parts of radix stemonae, 20-40 parts of fructus kochiae, 20-40 parts of dandelion, 20-40 parts of wild chrysanthemum flower, 20-40 parts of duckweed, 3-9 parts of frankincense and 3-9 parts of myrrh. The invention also discloses a using method of the Chinese herbal medicine compound preparation for treating eczema. The invention has convenient use and stable traditional Chinese medicine components in the medicinal juice, is directly absorbed by the affected part of the skin by wet dressing or soaking, quickly reaches the disease position and takes effect quickly. The traditional Chinese medicine preparation is reasonable in proportion, and the components have synergistic effect, so that the tedious and bad experience of taking the traditional Chinese medicine by a patient is avoided, and the related toxic and side effects are reduced.

Description

Chinese herbal medicine compound preparation for treating eczema and using method thereof

Technical Field

The invention relates to the technical field of Chinese herbal medicines, in particular to a Chinese herbal medicine compound preparation for treating eczema and a using method thereof.

Background

Eczema is a common skin disease, and the prevalence rate of eczema in general people in China is 7.5%, and the prevalence rate in America is 10.7%. In the south of Shanghai, yangtze and near the sea, the special geographical position of the Shanghai creates the climate. When the dampness is serious, eczema is easy to generate, and the dampness is serious, is easy to prolong and is difficult to cure, and belongs to common diseases which are difficult to cure. The disease is lingering and difficult to cure, the clinical treatment is troublesome, the physical and mental health of the patient is greatly influenced, the life quality of the patient is reduced, and severe patients can suffer from pruritus and insomnia. At present, the western medicine mainly treats the symptoms such as antihistamine medicines, glucocorticoid and astringent, protective preparations, and the like, can take effect in a short time, but is easy to generate drug dependence and has certain side effect. Therefore, finding safe and effective eczema treatment methods is a current research hotspot. And the occurrence of the traditional Chinese medicine wet compress well fills the effective treatment of eczema. At present, the clinical wet compress treatment of eczema has satisfied curative effect.

Disclosure of Invention

The invention aims to provide a Chinese herbal medicine compound preparation for treating eczema and a using method thereof, aiming at overcoming the defects and shortcomings of the prior art.

The technical problem solved by the invention can be realized by adopting the following technical scheme:

a Chinese herbal medicine compound preparation for treating eczema comprises the following main components in parts by weight: 40-60 parts of radix sophorae flavescentis, 40-60 parts of golden larch bark, 40-60 parts of radix stemonae, 20-40 parts of fructus kochiae, 20-40 parts of dandelion, 20-40 parts of wild chrysanthemum flower, 20-40 parts of duckweed, 3-9 parts of frankincense and 3-9 parts of myrrh.

In a preferred embodiment of the invention, the main components and the weight parts of the invention are as follows: 50 parts of radix sophorae flavescentis, 50 parts of golden larch bark, 50 parts of radix stemonae, 30 parts of fructus kochiae, 30 parts of dandelion, 30 parts of wild chrysanthemum flower, 30 parts of duckweed, 6 parts of frankincense and 6 parts of myrrh.

A using method of a Chinese herbal medicine compound preparation for treating eczema comprises the following steps:

step (1) preparation of a preparation: weighing the main components and the weight part ratio of the Chinese herbal medicine compound preparation for treating eczema and 5L of clear water;

soaking in the step (2): mixing the raw materials in the step (1) with clear water, and soaking for 30-50 minutes;

step (3) decocting: decocting in a pot, boiling, decocting for 25-35 min, removing residue, collecting decoction, metering the amount of the decoction, concentrating for 20-30 min, cooling to room temperature, bottling one by one, and bottling 250-350ml per bottle to obtain compound preparation;

the step (4) uses: soaking the affected part in the compound preparation, or applying the gauze soaked completely in the compound preparation to the affected part twice a day for 15-25 min each time.

In a preferred embodiment of the present invention, the soaking time in the step (2) is 40 minutes.

In a preferred embodiment of the present invention, in the step (3), the decoction is carried out under the condition of heat preservation for 30 minutes, and the concentration is carried out for 25 minutes, wherein the volume is 300ml per bottle.

In a preferred embodiment of the present invention, in the step (3), the decoction is carried out in a 50L steam jacketed kettle.

In a preferred embodiment of the present invention, said step (4) is performed for 20 minutes each.

Kuh-seng, also known as bitter bone, chuan Shen, fenghuang claw, etc. Bitter taste and cold nature. It enters liver, kidney, large intestine and small intestine meridians. Has the effects of clearing heat, eliminating dampness, dispelling pathogenic wind and killing parasites. It can be used for treating pudendal pruritus, scabies, tinea, leprosy, skin pruritus, and pyocutaneous disease due to damp toxin.

Cortex pseudolaricis is called cortex pseudolaricis and cortex pseudolaricis. It is pungent, warm and toxic. It enters lung and spleen meridians. Has the effects of killing parasites, relieving itching and treating scabies and pruritus. Can be used for treating tinea manus, tinea pedis, neurodermatitis, eczema, dysentery, and headache. The modern pharmacology proves that the medicine has the effect on ChinaCommonThe 10 pathogenic fungi all have certain antibacterial effect. The amount of the extract is 0.1-1mg/ml, and can be used for treating Trichophyton schoenleinii, epidermophyton floccosum, microsporum ferrugineum, microsporum gypseum and Microsporum sieboldiiCandida albicansIt has antibacterial effect.

Stemona root, radix Stemonae, sweet and bitter in nature and taste, and slightly warm. It enters lung meridian. Has little toxicity. Mainly used for moistening lung, descending qi, relieving cough and killing parasites. For a new-age cough; it is used for treating head louse, body louse, enterobiasis, and pudendal pruritus.

Di Fu Zi is pungent, bitter and cold in nature. It enters kidney and bladder meridians. Mainly used for clearing heat, promoting diuresis, dispelling wind and relieving itching. Can be used for treating difficult and painful urination, pruritus vulvae, leukorrhagia, rubella, eczema, and skin pruritus.

Dandelion is bitter and sweet in flavor and cold in nature. Enter liver and stomach meridians. Mainly used for clearing away heat and toxic material, promoting urination and resolving masses. It can be used for treating scrofula, furunculosis, and sore.

Wild chrysanthemum flower, bitter and pungent in property and slightly cold in nature. It enters liver and heart meridians. Mainly used for clearing away heat and toxic material. It can be used for treating furuncle, carbuncle, swelling, and conjunctival congestion with swelling and pain.

Duckweed, pungent in flavor and cold in nature. It enters lung meridian. Mainly used for dispersing wind-heat, promoting eruption and promoting urination. Can be used for treating measles without adequate eruption, rubella with pruritus, etc.

Ru Xiang is pungent, bitter and warm in nature. Enter heart, liver and spleen meridians. Mainly used for promoting blood circulation and relieving pain. Can be used for treating pain of heart and abdomen, spasm of tendons and vessels, traumatic injury, skin ulcer, carbuncle, and swelling and pain; it can be used topically for detumescence and granulation promotion. Modern pharmacology proves that the frankincense can promote the increase of multinucleated white blood cells, phagocytize dead blood cells and dead cells, improve metabolism and further play a role in diminishing inflammation.

Mo Yao is bitter in flavor and neutral in nature. Enter liver meridian. It is mainly used for dissipating blood stasis, relieving swelling and alleviating pain. It is indicated for traumatic injuries, pain in the heart and abdomen, abdominal mass, amenorrhea, abscess, deep-rooted carbuncle, swelling and pain. Modern pharmacology proves that the myrrh water immersion agent (1). The antibacterial action of myrrh may be related to eugenol. Mention has been made in Bencao gang mu: ru Xiang can activate blood and Mo Yao can alleviate pain and relieve swelling and promote tissue regeneration, so they are used together.

Due to the adoption of the technical scheme, the Chinese medicinal composition is convenient to use, the Chinese medicinal components in the medicinal juice are stable, and the Chinese medicinal composition can be directly absorbed by the affected part of the skin through wet dressing or soaking, quickly reaches the disease position and takes effect quickly. The traditional Chinese medicine preparation is reasonable in proportion, and the components have synergistic effect, so that the tedious and bad experience of taking the traditional Chinese medicine by a patient is avoided, and the related toxic and side effects are reduced.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further explained below.

Example 1

A Chinese herbal medicine compound preparation for treating eczema comprises the following main components in parts by weight: 50 parts of lightyellow sophora root, 50 parts of golden larch bark, 50 parts of sessile stemona root, 30 parts of belvedere fruit, 30 parts of dandelion, 30 parts of wild chrysanthemum flower, 30 parts of duckweed, 6 parts of frankincense and 6 parts of myrrh.

step (1) preparation of a preparation: weighing 50 parts of radix sophorae flavescentis, 50 parts of golden larch bark, 50 parts of radix stemonae, 30 parts of fructus kochiae, 30 parts of dandelion, 30 parts of wild chrysanthemum flower, 30 parts of duckweed, 6 parts of frankincense, 6 parts of myrrh and 5L of clear water;

step (2), soaking: mixing the raw materials in the step (1) with clear water and soaking for 40 minutes;

step (3) decocting: decocting in 50L steam jacketed pan, boiling, decocting for 30 min, removing residue, collecting decoction, metering medicinal liquid amount, concentrating for 25 min, cooling to normal temperature, bottling one by one, and bottling 300ml per bottle to obtain compound preparation;

the step (4) uses: soaking the affected part in the compound preparation, or applying the gauze soaked completely in the compound preparation to the affected part twice a day for 20 min each time.

Example 2

A Chinese herbal medicine compound preparation for treating eczema comprises the following main components in parts by weight: 40 parts of radix sophorae flavescentis, 40 parts of golden larch bark, 40 parts of radix stemonae, 20 parts of fructus kochiae, 20 parts of dandelion, 20 parts of wild chrysanthemum flower, 20 parts of duckweed, 3 parts of frankincense and 3 parts of myrrh.

step (1) preparation of a preparation: weighing 40 parts of radix sophorae flavescentis, 40 parts of golden larch bark, 40 parts of radix stemonae, 20 parts of fructus kochiae, 20 parts of dandelion, 20 parts of wild chrysanthemum flower, 20 parts of duckweed, 3 parts of frankincense, 3 parts of myrrh and 5L of clear water;

soaking in the step (2): mixing the raw materials in the step (1) with clear water and soaking for 40 minutes;

step (3) decocting: decocting in 50L steam jacketed pan, boiling, decocting for 30 min, removing residue, collecting decoction, metering the amount of the decoction, concentrating for 25 min, cooling to room temperature, bottling one by one, and bottling 300ml per bottle to obtain compound preparation;

the step (4) uses: soaking the local affected part in the compound preparation, or applying the gauze soaked completely in the compound preparation to the affected part twice a day for 20 min each time.

Example 3

A Chinese herbal medicine compound preparation for treating eczema comprises the following main components in parts by weight: 60 parts of radix sophorae flavescentis, 60 parts of golden larch bark, 60 parts of radix stemonae, 40 parts of fructus kochiae, 40 parts of dandelion, 40 parts of wild chrysanthemum flower, 40 parts of duckweed, 9 parts of frankincense and 9 parts of myrrh.

step (1) preparation of a preparation: weighing 60 parts of radix sophorae flavescentis, 60 parts of golden larch bark, 60 parts of radix stemonae, 40 parts of fructus kochiae, 40 parts of dandelion, 40 parts of wild chrysanthemum flower, 40 parts of duckweed, 9 parts of frankincense, 9 parts of myrrh and 5L of clear water;

Examples of therapeutic effects

Experimental example 1:40 cases were treated with cetirizine (1 granule for oral administration), with addition of example 1, and applied to the affected area wet twice daily.

Experimental example 2:40 cases were treated with cetirizine (1 granule for oral administration), and example 2 was added and applied to the affected area wet twice a day.

Experimental example 3:40 cases were treated with cetirizine (1 granule for oral administration), with addition of example 3, and applied to the affected area wet twice daily.

Comparative example 1:40 cases are treated with cetirizine (1 granule taken orally), added with compound beclomethasone camphor cream, and applied externally twice a day.

Comparative example 2:40 cases, treating with cetirizine (1 granule oral), adding three medicines of example 1 except cortex pseudolaricis, frankincense and myrrh, and wet-applying on affected parts twice a day.

The exemplary effects of the therapeutic effects are shown in Table 1 below

TABLE 1

As can be seen from the comparative data in Table 1, the skin damage of the patients is obviously reduced after the medicine is applied to the affected part. The present invention can be safely used in the affected parts (such as the face, the breast, the periphery of the external genitalia, the parts close to the mucosa, etc.) where the hormone external medicine cannot be used. And follow-up for 3 months after use, only 2 cases recurred. The method has obvious advancement in both effects and application range.

Typical cases are as follows:

1. liu Jie, male, age 44. Initial diagnosis in 12 months and 2 days in 2020. The erythema and desquamation of both feet and palms of both hands of a patient are accompanied by pruritus for more than 2 years, the pruritus is repeated, small blisters appear seriously, the pruritus is serious, the skin damage is hypertrophic after repeated scratching and becomes lichenification, and the itching is particularly serious when the patient enters the night, thus the sleep is seriously influenced. The externally applied hormone ointment is used by oneself, and the disease is effective when the ointment is used, and the disease recurs after the ointment is stopped. The patients were first diagnosed that the itching was slightly relieved after 3 weeks of self-decoction and wet-dressing according to example 1 of the present invention, but the itching became worse after the night. Considering that the patient suffers from a long-term disease, the disease is aggravated in the night, the diseased position is already affected by the blood, and the patient is treated as both qi and blood. After the invention is used for 4 weeks, the skin damage is reduced and the pruritus is relieved. After 2 months of use, the skin lesion part basically recovers, and only a small amount of color is left.

2. Zhu Chi, woman, 50 years old. Initial diagnosis in 10 months and 13 days in 2020. The patients have no obvious reason for reddish erythema multiforme on limbs and trunk 1 year ago, and pruritus is mild and severe. After the patient uses the medicine of the invention in the embodiment 1 and is matched with antihistamine medicine, the pruritus of the patient is reduced, and after the patient is matched with the intermittent use for half a year, the patient has no relapse after the follow-up visit for 3 months.

3. Lie, male, 72 years old. First diagnosis in 2 days 6 month in 2020. Erythema pimple, pruritus and exudation are generated around the anus and in the groin of the patient, the patient has repeated attack and cannot tolerate the erythema pimple, and the condition is difficult to heal because the ointment containing hormone is not suitable for being used near the genital mucosa. After 2 weeks of hip bath of example 1 of the present invention, itching was reduced and exudation was reduced. And the patient has no discomfort and no irritation to mucous membrane after use. After 2 months of use, the skin damage is obviously reduced, and no liquid seepage occurs.

The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A Chinese herbal medicine compound preparation for treating eczema is characterized by comprising the following raw material medicines in parts by weight: 50 parts of radix sophorae flavescentis, 50 parts of golden larch bark, 50 parts of radix stemonae, 30 parts of fructus kochiae, 30 parts of dandelion, 30 parts of wild chrysanthemum flower, 30 parts of duckweed, 6 parts of frankincense and 6 parts of myrrh;

the preparation method of the Chinese herbal medicine compound preparation comprises the following steps:

step (1) preparation of a preparation: weighing 5L of raw material medicines and clear water according to the weight part ratio;

soaking in the step (2): mixing the raw material medicaments in the step (1) with clear water and soaking for 40 minutes;

step (3) decocting: decocting in 50L steam jacketed pan, boiling, decocting for 30 min, removing residue, collecting decoction, metering the amount of the decoction, concentrating for 25 min, cooling to room temperature, and bottling one by one (300 ml per bottle) to obtain compound preparation.