CN105031596A - Ointment for treating nummular eczema and preparing method thereof - Google Patents

Abstract

The invention discloses ointment for treating nummular eczema and a preparing method thereof. The prepared ointment comprises, by weight, 25-30 parts of purslane, 6-8 parts of fructus cnidii, 5-9 parts of radix clematidis, 9-15 parts of radix sophorae flavescentis, 15-20 parts of fresh ginger, 8-12 parts of fresh maidenhair, 15-20 parts of carmine radish, 5-8 parts of corydalis incisa, 8-10 parts of radix stemonae, 10-15 parts of cortex dictamni, 9-12 parts of broom cypress fruits, 5-8 parts of common hogfennei roots, 3-5 parts of medicago falcata, 9-13 parts of stachys affinis tubers, 10-15 parts of goose fatty, 20-30 parts of olive oil, 8-12 parts of radix glycyrrhizae preparata and 6-8 parts of periostracum cicada. The ointment is an externally applied agent and directly acts on the infected part. The ointment can effectively remove rheumatic fever evil invading to the skin, kill worms, diminish inflammation, cure nummular eczema once and for all, quickly and effectively relieve the pruritus symptoms at the infected part and promote skin recovery at the infected part. Pure traditional Chinese medicine preparations are adopted in the ointment, the defects of western medicine treatment are avoided, the ointment is safe, free of toxic and side effect and obvious in treatment effect, and relapse cannot occur easily.

Description

A kind of ointment machin its preparation method for the treatment of nummular eczema

Technical field

The present invention relates to the field of Chinese medicines, particularly a kind of ointment machin its preparation method for the treatment of nummular eczema.

Background technology

Nummular eczema is also known as nummular eczematous dermatitis or discoid eczema., it can there is pimple, vesicle, slight erosion, ooze out, the acute or subacute performance such as incrustation in the red patch of the circle of skin lesion in the about five-cent piece size be dispersed in.Damage rare have be greater than diameter 10cm person, border is clearer, can single-shot or multiple, be often chronic, in the scaling infringement of slight lichen sample, central clearing sometimes, seemingly epidermis tinea sample.Normal symmetry generation, is more common in the back of the hand and extremity stretch side, back, and conscious violent pruritus, is common in male, and onset peak was at 55 ~ 65 years old, and women was also onset peak at 15 ~ 25 years old, and child is rare.Mostly in chronic process, indivedual infringement is for a long time sustainable, and how recurrent exerbation in process, increase the weight of in the winter time or recur, and has the feature in former affected area recurrence in the past.Current without specific treatment method, take the Therapeutic Method identical with eczema, external corticosteroids medicine, interim suppression therapy more.But this treatment means is cured the symptoms, not the disease, the state of an illness still can recurrent exerbation, and the long-time or heavy dose of external of short-term uses corticosteroids medicine, and also likely addiction causes drug dependence dermatitis.

Nummular eczema should belong to " exudative dermatitis " category in theory of Chinese medical science, waits record as " General Treatise on the Cause and Symptoms of Diseases " exudative dermatitis: " exudative dermatitis person, also rectify Guo, as worm row, contamination, also pruritus due to damp pathogen, the succulence scratched becomes skin ulcer, and be its wind, poison is shallow, wet windy few, therefore be exudative dermatitis also ".This disease is many to be formed because rheumatism pathogenic heat invades skin.Adopt tcm therapy, explore the method for safe and effective this disease of radical cure, there is profound significance.

Summary of the invention

The present invention is according to traditional Chinese medical science Synergy, the skin cause of disease is invaded for causing the rheumatism pathogenic heat of nummular eczema, a kind of ointment machin its preparation method for the treatment of nummular eczema is provided, this ointment is medicine for external use, directly act on affected part, effectively can remove the rheumatism pathogenic heat invading skin, this disease is effected a radical cure in parasite killing antiinflammatory, can effectively alleviate affected part pruritis fast simultaneously, promote that affected part skin recovers, this ointment adopts pure Chinese medicinal preparation, avoids the drawback of western medical treatment, safe without toxic side effect, evident in efficacy and not easily recur.

To achieve these goals, technical scheme provided by the invention is as follows:

A kind of ointment for the treatment of nummular eczema, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 25-30 part, Fructus Cnidii 6-8 part, Radix Clematidis 5-9 part, Radix Sophorae Flavescentis 9-15 part, Rhizoma Zingiberis Recens 15-20 part, Herba Tagetis Patulae fresh goods 8-12 part, rouge radish 15-20 part, carves and splits Herba corydalis edulis 5-8 part, Radix Stemonae 8-10 part, Cortex Dictamni 10-15 part, Fructus Kochiae 9-12 part, Radix Peucedani 5-8 part, Herba Meliloti Suaveolentis 3-5 part, Chinese artichoke tuber 9-13 part, Anaer Cygnoides domestica Brisson 10-15 part, olive oil 20-30 part, Radix Glycyrrhizae Preparata 8-12 part, Periostracum Cicadae 6-8 part.

Preferably, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 25 parts, Fructus Cnidii 6 parts, Radix Clematidis 5 parts, Radix Sophorae Flavescentis 9 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 8 parts, rouge radish 15 parts, carves and splits Herba corydalis edulis 5 parts, the Radix Stemonae 8 parts, Cortex Dictamni 10 parts, the Fructus Kochiae 9 parts, Radix Peucedani 5 parts, Herba Meliloti Suaveolentis 3 parts, 9 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 10 parts, 20 parts, olive oil, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.

Preferably, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 30 parts, Fructus Cnidii 8 parts, Radix Clematidis 9 parts, Radix Sophorae Flavescentis 15 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 12 parts, rouge radish 20 parts, carves and splits Herba corydalis edulis 8 parts, the Radix Stemonae 10 parts, Cortex Dictamni 15 parts, the Fructus Kochiae 12 parts, Radix Peucedani 8 parts, Herba Meliloti Suaveolentis 5 parts, 13 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 15 parts, 30 parts, olive oil, Radix Glycyrrhizae Preparata 12 parts, Periostracum Cicadae 8 parts.

Preferably, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 28 parts, Fructus Cnidii 7 parts, Radix Clematidis 7 parts, Radix Sophorae Flavescentis 12 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 10 parts, rouge radish 18 parts, carves and splits Herba corydalis edulis 7 parts, the Radix Stemonae 9 parts, Cortex Dictamni 12 parts, the Fructus Kochiae 10 parts, Radix Peucedani 6 parts, Herba Meliloti Suaveolentis 4 parts, 11 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 12 parts, 25 parts, olive oil, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 7 parts.

Present invention also offers the preparation method of the ointment of described treatment nummular eczema, comprise the following steps:

(1) split Herba corydalis edulis at Fructus Cnidii, Radix Clematidis, Radix Sophorae Flavescentis, quarter, water soaking that the Radix Stemonae, the Fructus Kochiae, Radix Peucedani, Herba Meliloti Suaveolentis, Radix Glycyrrhizae Preparata, Periostracum Cicadae add gross mass multiple 4 times 1 hour, slow fire boiling 2 hours, cross 1000 order drainage screens after decocting and obtain filtrate, it is for subsequent use that gained filtrate is cooled to room temperature;

(2) Herba Portulacae, Rhizoma Zingiberis Recens, Herba Tagetis Patulae, rouge radish, Chinese artichoke tuber mixing clean, add step (1) gained filtrate mixing squeeze the juice after leave standstill 2 hours, cross 200 order filter screen filtration, respectively collect filtrate and filtering residue for subsequent use;

(3) step (2) gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.35 ± 0.02 (30 DEG C);

(4) mix with Cortex Dictamni after the vacuum lyophilization of step (2) gained filtering residue, be ground into 1000 object mixed-powders with super micron mill, for subsequent use;

(5) in the thick paste of step (3), add the mixed-powder that step (4) is obtained, then add olive oil, Anaer Cygnoides domestica Brisson fully stirs, mix homogeneously, must treat the unguentum of stasis dermatitis.

Nummular eczema is many to be formed because rheumatism pathogenic heat invades skin, also can be caused by extraneous pathogen chafe infection or allergy.Ointment of the present invention is from the pathogenesis of this disease, consider the symptom of patient affected part pruritus simultaneously, take removing damp-heat, parasite killing antiinflammatory, antipruritic effect and promoting granulation method treat this disease, this ointment directly acts on affected part, effective rheumatism pyretic toxicity removing intrusion skin, kills extraneous pathogenic former, effects a radical cure this disease, effectively alleviate affected part pruritis fast simultaneously, promote that affected part skin recovers.According to Chinese medical theory determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, screen raw material of Chinese medicine by great many of experiments, refining agent method, make each efficacy of drugs produce synergism, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.In the crude drug chosen: Herba Portulacae: cold in nature, sweet in the mouth acid, enter the heart, liver, spleen, large intestine channel, have that removing dampness is antipruritic, clearing heat for detumescence, heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of hemostasis removing heat from blood.Herba Portulacae is to dysentery bacterium, Bacillus typhi and escherichia coli have stronger inhibitory action, can be used for the auxiliary treatment of various inflammation, have the title of " natural antibiotics ", Herba Portulacae is also rich in vitamin C simultaneously, vitamin C has good antioxidation can whitening nourishes rough skin, modern medicine finds, Herba Portulacae has higher nutritive value and medical value, except the protein containing routine, outside the nutrient such as vitamin and mineral, Herba Portulacae is also containing unique bioactive ingredients, the activity of Human Epithelial Cells can be strengthened, help lend some impetus to ulcer and healing, Fructus Cnidii: warm in nature, bitter in the mouth, warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing, for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, external treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis, Radix Clematidis: taste is micro-pungent salty, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump, cures mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs, because its property is walked to alter, pharmacology confirms that it removes the effect of place's smooth muscle spasms such as esophagus, bronchus, ureter, stomach and biliary tract in addition, and has stronger anti-inflammatory analgetic effect, Radix Sophorae Flavescentis: bitter, cold, there is heat clearing and damp drying, parasite killing, the merit of diuresis, for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis, Rhizoma Zingiberis Recens: pungent and loose temperature, strengthening the spleen stomach, kind warming middle-JIAO to send down the adverse QI preventing or arresting vomiting, dehumidify the painful abdominal mass that disappears, eliminating phlegm and stopping cough, take stopping nausea and vomiting by lowering the adverse flow of QI as length, scientific research finds, Rhizoma Zingiberis Recens can play the effect of some antibiotics, especially to Salmonella better effects if, ginger extract has the effect significantly suppressing dermatophytes and kill connections trichomonas vaginitis, can treat various carbuncle sore tumefacting virus, Herba Tagetis Patulae: bitter, flat, clearing away heat-damp and promoting diuresis, cough-relieving, pain relieving, for upper respiratory tract infection, dysentery, cough, pertussis, toothache, acute conjunctivitis due to pathogenic windfire, parotitis is controlled in external, mastitis, rouge radish: Radix Raphani is cool in nature, acrid in the mouth, sweet, there is removing food stagnancy stagnant, reducing phlegm and fever, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, effect of removing toxic substances, can enhance metabolism, appetite stimulator, help digest, can eliminate indigestion stagnant, often eat Radix Raphani and can reduce blood fat, vessel softening, stabilizing blood pressure, coronary heart disease can be prevented, arteriosclerosis, cholelithiasis and other diseases, rouge radish is except having the effect of common Radix Raphani, also be rich in anthocyanidin and anthocyanin, anthocyanidin is a kind of strong antioxidant, it can protect human body from the damage of free radical, anthocyanidin can also strengthen blood vessel elasticity, improve the smoothness of blood circulation and enhancement skin, inflammation-inhibiting and allergy, quarter splits Herba corydalis edulis: bitter, puckery, cold, and removing toxic substances parasite killing, cures mainly sore, leprosy dysentery head, stubborn dermatitis, venom, the Radix Stemonae: sweet, bitter, tepor, nourishing the lung to keep the adverse QI downward cough-relieving, killing parasites for relieving itching, coughs for new chronic cough, pulmonary tuberculosis cough, pertussis, outward for head louse, body louse, enterobiasis, pudendal pruritus, Cortex Dictamni: heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances, cures mainly the rubella caused by wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia, the Fructus Kochiae: cold in nature, acrid in the mouth, hardship, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, for difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus, Radix Peucedani: bitter, pungent, is slightly cold, loose wind heat clearing away, lowering the adverse-rising QI to resolve phlegm, and for cough due to pathogenic wind-heat's abundant expectoration, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick, Herba Meliloti Suaveolentis: bitter light, cool, nontoxic, heat clearing away, removing toxic substances, removing dampness, parasite killing.Control summer-heat uncomfortable in chest, malaria, dysentery, gonorrhea, sores ulceration of skin; Chinese artichoke: sweet, flat, the diarrhea of heat type that dispels the wind wets, promoting blood circulation to remove blood stasis.For jaundice, urinary tract infection, anemopyretic cold, pulmonary tuberculosis, external is controlled sore and is swollen and ache, snake bite and insect sting; Anaer Cygnoides domestica Brisson: sweet in the mouth, cool in nature, profit skin, removing toxic substances is swollen, cures mainly skin and is chapped from the cold, deaf, Ting ear, dysphagia and regurgitation, drug intoxication, carbuncle, scabies etc.; Olive oil: be rich in monounsaturated fatty acid, has the effect of antiinflammatory, to blood vessel and joint all beneficial; Radix Glycyrrhizae Preparata: containing number of chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, there is antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and analgesic effect, therefore the primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Periostracum Cicadae: sweet in the mouth, salty, cool in nature, dispelling wind and heat pathogens, relieving sore throat to recover voice, rash, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion, can reach skin by priming.

In all medicines, Radix Sophorae Flavescentis, Herba Portulacae are monarch drug, play the effect of removing damp-heat, parasite killing antiinflammatory, antipruritic effect and promoting granulation, for this cause of disease and this disease for the treatment of for diseases.Split Herba corydalis edulis at Fructus Cnidii, Radix Clematidis, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods, rouge radish, quarter, the Radix Stemonae, Cortex Dictamni, the Fructus Kochiae, Radix Peucedani, Herba Meliloti Suaveolentis, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson, olive oil be ministerial drug, wherein, Fructus Cnidii, Radix Clematidis, Rhizoma Zingiberis Recens, Herba Tagetis Patulae, rouge radish, Cortex Dictamni, the Fructus Kochiae, Radix Peucedani, Herba Meliloti Suaveolentis, Chinese artichoke and monarch drug are with using, can the effect of gain monarch drug removing damp-heat, effective ingredient directly acts on affected part by Transdermal absorption, effective rheumatism pyretic toxicity removing intrusion skin, effects a radical cure this disease, split Herba corydalis edulis, the Radix Stemonae, Herba Meliloti Suaveolentis at Fructus Cnidii, Radix Clematidis, Rhizoma Zingiberis Recens, quarter, olive oil can the effect of gain monarch drug parasite killing antiinflammatory, directly act on affected part and effectively diminish inflammation, kill external etiology, promote that patient recovers, rouge radish, Anaer Cygnoides domestica Brisson, Cortex Dictamni, the Fructus Kochiae, the Radix Stemonae can the effect of gain monarch drug antipruritic effect and promoting granulation, effectively alleviate affected part pruritis fast, promote illing skin rehabilitation, wherein, rouge radish is rich in anthocyanidin and anthocyanin, there is stronger antioxidation, skin can be protected from the damage of free radical, anthocyanidin can also strengthen blood vessel elasticity, improve blood circulation, thus recover the blood microcirculation in affected part, the immunocyte in blood and the nutritional labeling needed for skin repair is made to arrive affected part by blood circulation, the immune system of patient self is played one's part to the full, give the nutrient that the recovery of affected part skin provides sufficient simultaneously, rouge radish is contained that anthocyanidin also has inflammation-inhibiting and irritated effect, this medicine is made also to have good curative effect to the nummular eczema that allergy causes.Radix Glycyrrhizae Preparata is assistant, and Radix Glycyrrhizae Preparata plays harmonizing yingfen and weifen, plays the effect of warming spleen and stomach for dispelling cold.Periostracum Cicadae, for drawing, can reach skin by priming, better treat dermatosis.Ointment of the present invention is pure Chinese medicinal preparation, and selected medical material compatibility is suitable, and adopts modern advanced medical pharmaceutical technology to make, for this disease of cause of disease treatment for diseases, there is treating both the principal and secondary aspects of a disease rapid-action, and be external used medicine, use safer, have no side effect, evident in efficacy.

Beneficial effect of the present invention is: the invention provides a kind of ointment machin its preparation method for the treatment of nummular eczema.This ointment is from the pathogenesis of this disease, consider the symptom of patient affected part pruritus simultaneously, take removing damp-heat, parasite killing antiinflammatory, antipruritic effect and promoting granulation method treat this disease, this ointment directly acts on affected part, effective rheumatism pyretic toxicity removing intrusion skin, kills extraneous pathogenic former, effects a radical cure this disease, effectively alleviate affected part pruritis fast simultaneously, promote that affected part skin recovers.According to Chinese medical theory determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, screen raw material of Chinese medicine by great many of experiments, refining agent method, make each efficacy of drugs produce synergism, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.This medicine is pure Chinese medicinal preparation, and selected medical material compatibility is suitable, and adopts modern advanced medical pharmaceutical technology to make, external safe without toxic side effect and evident in efficacy.Wherein, selected crude drug rouge radish is rich in anthocyanidin and anthocyanin, there is stronger antioxidation, skin can be protected from the damage of free radical, anthocyanidin can also strengthen blood vessel elasticity, improve blood circulation, thus recover the blood microcirculation in affected part, the immunocyte in blood and the nutritional labeling needed for skin repair is made to arrive affected part by blood circulation, the immune system of patient self is played one's part to the full, give the nutrient that the recovery of affected part skin provides sufficient simultaneously, rouge radish is contained that anthocyanidin also has inflammation-inhibiting and irritated effect, this medicine is made also to have good curative effect to the nummular eczema that allergy causes.Radix Glycyrrhizae Preparata is assistant, and Radix Glycyrrhizae Preparata plays harmonizing yingfen and weifen, plays the effect of warming spleen and stomach for dispelling cold.Periostracum Cicadae, for drawing, can reach skin by priming, better treat dermatosis.

Detailed description of the invention

According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, concrete material proportion, process conditions and result thereof described by embodiment only should can not limit the present invention described in detail in claims yet for illustration of the present invention.

Embodiment 1

Treat an ointment for nummular eczema, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 25 parts, Fructus Cnidii 6 parts, Radix Clematidis 5 parts, Radix Sophorae Flavescentis 9 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 8 parts, rouge radish 15 parts, carves and splits Herba corydalis edulis 5 parts, the Radix Stemonae 8 parts, Cortex Dictamni 10 parts, the Fructus Kochiae 9 parts, Radix Peucedani 5 parts, Herba Meliloti Suaveolentis 3 parts, 9 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 10 parts, 20 parts, olive oil, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.

The preparation method of this ointment, comprises the following steps:

(1) split Herba corydalis edulis at Fructus Cnidii, Radix Clematidis, Radix Sophorae Flavescentis, quarter, water soaking that the Radix Stemonae, the Fructus Kochiae, Radix Peucedani, Herba Meliloti Suaveolentis, Radix Glycyrrhizae Preparata, Periostracum Cicadae add gross mass multiple 4 times 1 hour, slow fire boiling 2 hours, cross 1000 order drainage screens after decocting and obtain filtrate, it is for subsequent use that gained filtrate is cooled to room temperature;

(2) Herba Portulacae, Rhizoma Zingiberis Recens, Herba Tagetis Patulae, rouge radish, Chinese artichoke tuber mixing clean, add step (1) gained filtrate mixing squeeze the juice after leave standstill 2 hours, cross 200 order filter screen filtration, respectively collect filtrate and filtering residue for subsequent use;

(3) step (2) gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.35 ± 0.02 (30 DEG C);

(4) mix with Cortex Dictamni after the vacuum lyophilization of step (2) gained filtering residue, be ground into 1000 object mixed-powders with super micron mill, for subsequent use;

(5) in the thick paste of step (3), add the mixed-powder that step (4) is obtained, then add olive oil, Anaer Cygnoides domestica Brisson fully stirs, mix homogeneously, must treat the unguentum of stasis dermatitis.

Embodiment 2

Treat an ointment for nummular eczema, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 30 parts, Fructus Cnidii 8 parts, Radix Clematidis 9 parts, Radix Sophorae Flavescentis 15 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 12 parts, rouge radish 20 parts, carves and splits Herba corydalis edulis 8 parts, the Radix Stemonae 10 parts, Cortex Dictamni 15 parts, the Fructus Kochiae 12 parts, Radix Peucedani 8 parts, Herba Meliloti Suaveolentis 5 parts, 13 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 15 parts, 30 parts, olive oil, Radix Glycyrrhizae Preparata 12 parts, Periostracum Cicadae 8 parts.

The preparation method of the ointment of embodiment 2 is identical with embodiment 1.

Embodiment 3

Treat an ointment for nummular eczema, crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 28 parts, Fructus Cnidii 7 parts, Radix Clematidis 7 parts, Radix Sophorae Flavescentis 12 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 10 parts, rouge radish 18 parts, carves and splits Herba corydalis edulis 7 parts, the Radix Stemonae 9 parts, Cortex Dictamni 12 parts, the Fructus Kochiae 10 parts, Radix Peucedani 6 parts, Herba Meliloti Suaveolentis 4 parts, 11 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 12 parts, 25 parts, olive oil, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 7 parts.

The preparation method of the ointment of embodiment 3 is identical with embodiment 1.

Embodiment 4 hypersensitive test

Get healthy albino guinea-pig 18, body weight 250-300g, male and female dual-purpose, reject both sides dorsal body setae before test, every side 3 × 3cm, is divided into test group, blank group and positive controls positive controls with 2 at random, 4-dinitrochlorobenzene, sensitization 1% concentration, excites and uses 0.1% concentration; The test group ointment of the embodiment of the present invention 1.The ointment getting the embodiment of the present invention 1 is applied to unhairing district, back, the next day 1 time, totally 3 times.In latter 14 days of last contact, smear this ointment at back the same area, at once observe after removing medicine after 6h, and in 24,48,72h observes with or without anaphylaxis.Blank group and positive controls excite by same method and contact and observe.Result of the test: namely positive controls animal skin occurs localized erythema and slight edema in sensitization after 1 hour, within 24 hours, symptoms of allergic increases the weight of, sensitization rate is 100%, and any symptoms of allergic does not all appear in test group and blank treated animal skin, and sensitization rate is 0%.Experimental result shows that ointment formula gentleness of the present invention is non-stimulated.

Embodiment 5 clinical trial:

Random selecting 150 nummular eczema patients carry out clinical experiment, patient age 23-65 year, average 42 years old, using this disease of Ointment in Treatment of the present invention, be applied to affected part 2 times on the one, 7th is a course for the treatment of, investigate the curative effect of traditional Chinese herb medicine of the present invention, the evaluation criterion of curative effect is:

Recovery from illness: patient condition disappears completely, and healing nothing recurrence in 3 months;

Effective: patient condition alleviates, as pruritis is alleviated, nummular eczema minimizing etc.;

Invalid: the unchanged or aggravation of patient condition.

Statistical result is as follows:

	Embodiment 1	Embodiment 2	Embodiment 3
				Recovery from illness	32	35	33
Effective	16	15	16
				Invalid	2	0	1
Effective percentage	96	100	98

Experimental result can be found out, the effective percentage of Ointment in Treatment nummular eczema of the present invention can reach more than 96%, and all patients all had no adverse reaction in the medication stage.

Clinical model case:

Often certain, male, 60 years old, the clear-cut circular skin lesion of diameter 10cm is there is outside right thigh, in the scaling infringement of slight lichen sample, central clearing, like epidermis tinea sample, conscious pruritus is abnormal, is nummular eczema through hospital diagnosis, external mupirocin Ointment in Treatment, recurs more repeatedly, adopts the Ointment in Treatment of the embodiment of the present invention 1, medication scratchiness on the same day obviously alleviates, after 1 course for the treatment of, skin lesion returns to one's perfect health recovery from illness, and rear 3 months without recurrence.

King so-and-so, female, 23 years old, left arm occur multiple the circular red grouper sheet skin lesion of about five-cent piece size, slight erosion also has transudate, affected part pain is itched hard to bear, uses Jiang Shi to defend after skin frost fails to respond to any medical treatment, uses the Ointment in Treatment of the embodiment of the present invention 2, medication scratchiness on the same day obviously alleviates, after 1 course for the treatment of, skin lesion returns to one's perfect health recovery from illness, heals 3 months without recurrence.

Money, man, 55 years old, right side palm occurs without reason the red patch of the circle of multiple coin-size, pruritus pain was hard to bear, be nummular eczema through hospital diagnosis, use the Ointment in Treatment of the embodiment of the present invention 3, medication scratchiness on the same day obviously alleviates, after 1 course for the treatment of, skin lesion returns to one's perfect health recovery from illness, heals 3 months without recurrence.

Above embodiment is only for illustrating technical conceive of the present invention and feature; its object is to allow person skilled in the art understand content of the present invention and to be implemented; can not limit the scope of the invention with this; all equivalences done according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention.

Claims (5)

1. treat the ointment of nummular eczema for one kind, it is characterized in that: crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 25-30 part, Fructus Cnidii 6-8 part, Radix Clematidis 5-9 part, Radix Sophorae Flavescentis 9-15 part, Rhizoma Zingiberis Recens 15-20 part, Herba Tagetis Patulae fresh goods 8-12 part, rouge radish 15-20 part, carves and splits Herba corydalis edulis 5-8 part, Radix Stemonae 8-10 part, Cortex Dictamni 10-15 part, Fructus Kochiae 9-12 part, Radix Peucedani 5-8 part, Herba Meliloti Suaveolentis 3-5 part, Chinese artichoke tuber 9-13 part, Anaer Cygnoides domestica Brisson 10-15 part, olive oil 20-30 part, Radix Glycyrrhizae Preparata 8-12 part, Periostracum Cicadae 6-8 part.

2. a kind of ointment for the treatment of nummular eczema as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 25 parts, Fructus Cnidii 6 parts, Radix Clematidis 5 parts, Radix Sophorae Flavescentis 9 parts, 15 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 8 parts, rouge radish 15 parts, carves and splits Herba corydalis edulis 5 parts, the Radix Stemonae 8 parts, Cortex Dictamni 10 parts, the Fructus Kochiae 9 parts, Radix Peucedani 5 parts, Herba Meliloti Suaveolentis 3 parts, 9 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 10 parts, 20 parts, olive oil, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.

3. a kind of ointment for the treatment of nummular eczema as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 30 parts, Fructus Cnidii 8 parts, Radix Clematidis 9 parts, Radix Sophorae Flavescentis 15 parts, 20 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 12 parts, rouge radish 20 parts, carves and splits Herba corydalis edulis 8 parts, the Radix Stemonae 10 parts, Cortex Dictamni 15 parts, the Fructus Kochiae 12 parts, Radix Peucedani 8 parts, Herba Meliloti Suaveolentis 5 parts, 13 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 15 parts, 30 parts, olive oil, Radix Glycyrrhizae Preparata 12 parts, Periostracum Cicadae 8 parts.

4. a kind of ointment for the treatment of nummular eczema as claimed in claim 1, is characterized in that: crude drug composition and the parts by weight of making described ointment are: Herba Portulacae 28 parts, Fructus Cnidii 7 parts, Radix Clematidis 7 parts, Radix Sophorae Flavescentis 12 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Tagetis Patulae fresh goods 10 parts, rouge radish 18 parts, carves and splits Herba corydalis edulis 7 parts, the Radix Stemonae 9 parts, Cortex Dictamni 12 parts, the Fructus Kochiae 10 parts, Radix Peucedani 6 parts, Herba Meliloti Suaveolentis 4 parts, 11 parts, Chinese artichoke tuber, Anaer Cygnoides domestica Brisson 12 parts, 25 parts, olive oil, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 7 parts.

5. a kind of preparation method for the treatment of the ointment of nummular eczema as described in Claims 1-4, is characterized in that: comprise the following steps:

(1) split Herba corydalis edulis at Fructus Cnidii, Radix Clematidis, Radix Sophorae Flavescentis, quarter, water soaking that the Radix Stemonae, the Fructus Kochiae, Radix Peucedani, Herba Meliloti Suaveolentis, Radix Glycyrrhizae Preparata, Periostracum Cicadae add gross mass multiple 4 times 1 hour, slow fire boiling 2 hours, cross 1000 order drainage screens after decocting and obtain filtrate, it is for subsequent use that gained filtrate is cooled to room temperature;

(2) Herba Portulacae, Rhizoma Zingiberis Recens, Herba Tagetis Patulae, rouge radish, Chinese artichoke tuber mixing clean, add step (1) gained filtrate mixing squeeze the juice after leave standstill 2 hours, cross 200 order filter screen filtration, respectively collect filtrate and filtering residue for subsequent use;

(3) step (2) gained filtrate adds in low-temperature vacuum thickener, and cryoconcentration (less than 40 DEG C) to relative density is the thick paste of 1.35 ± 0.02 (30 DEG C);

(4) mix with Cortex Dictamni after the vacuum lyophilization of step (2) gained filtering residue, be ground into 1000 object mixed-powders with super micron mill, for subsequent use;

(5) in the thick paste of step (3), add the mixed-powder that step (4) is obtained, then add olive oil, Anaer Cygnoides domestica Brisson fully stirs, mix homogeneously, must treat the unguentum of stasis dermatitis.