CN101601782B - Compound tincture for treating dermatophytosis - Google Patents

Compound tincture for treating dermatophytosis Download PDF

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CN101601782B
CN101601782B CN2009100148455A CN200910014845A CN101601782B CN 101601782 B CN101601782 B CN 101601782B CN 2009100148455 A CN2009100148455 A CN 2009100148455A CN 200910014845 A CN200910014845 A CN 200910014845A CN 101601782 B CN101601782 B CN 101601782B
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CN101601782A (en
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李文良
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Yangzhong Productivity Promotion Center
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Abstract

The invention discloses a compound tincture for treating dermatophytosis, which has good curative effect and no side effect and reaches the effect of treating both the symptoms and root causes by toxin expelling, inflammation diminishing, sterilization, restoration, skin cell reactivation, and epidermis microcirculation promotion for skin refinement. The compound tincture for treating dermatophytosis comprises the following raw materials according to weight ratio: ethanol of each 100 parts comprises traditional Chinese medicine raw materials, such as 10 to 20 parts of potassium permanganate, 10 to 20 parts of salicylic acid, 10 to 20 parts of vinegar, 8 to 15 parts of broomjutre sida herb, 8 to 15 parts of loewigite, 8 to 15 parts of yellow-corktree bark, 8 to 15 parts of cuttlebone, 8 to 15 parts of cortex dictamni radicis, 8 to 15 parts of cnidium fruit, 8 to 15 parts of Chinese honeylocust fruit, 6 to 10 parts of calamus, 6 to 10 parts of balsam, 4 to 8 parts of kuh-seng, 4 to 8 parts of lilac, 4 to 8 parts of borneol, 4 to 8 parts of sulfur, 4 to 8 parts of xanthium sibiricum, 4 to 8 parts of honeycomb, 4 to 8 parts of uncaria stem with hooks, 1 to 5 parts of realgar, 1 to 5 parts of camphor, 1 to 5 parts of mercurous chloride, 1 to 5 parts of calamine, 1 to 5 parts of litharge, 1 to 5 parts of phaseolus calcaratus, 8 to 15 parts of peppermint oil and the like which are matched.

Description

A kind of compound spirit for the treatment of tinea pedis
Technical field
The present invention relates to a kind of medicine for the treatment of acne, a kind of specifically compound spirit for the treatment of tinea pedis.
Background technology
Beriberi, motherland's medical science are called " smelly Cipangopaludina chinensis ", " beriberi ", " tinea pedis ", " beriberi eczema ", " beriberi caused by pathogenic damp ", " the mashed skin ulcer of toes seam ", " mashed skin ulcer ", " pruritus due to wind pathogen foot sore ", " mashed foot wind ", " foot hemorrhoid ".As " Yizong Jinjian surgery heart method ": " this card is given birth to through damp invasion of lower energizer by stomach, foot bifurcation junk, though its trouble is little, can not the separating of its stranding of itching must be rubbed with the hands to skin mashedly, and when the stench water in Tianjin was felt pain, only still itching next day in its side of itching, does not heal year in year out, extremely touching." though this disease occurs in hands, foot is local, and pruritus pain is often arranged, and sometimes because of the secondary pyogenic infection of scratching, or causes lymph node, lymphangitis and erysipelas, septicemia etc., to working, healthy certain influence being arranged all, must be paid attention to.Beriberi is the popular name of tinea pedis.The somebody lumps together " beriberi " and " vitamin B1 deficiency ", and this is not right." vitamin B1 deficiency " medically is the systemic disease that causes because of Vitamin B deficiency, and " beriberi " then is to infect caused a kind of common skin diseases by fungus (claiming toadstool).The foot basin and the towel that wipes one's feet should use respectively in order to avoid infect other people.Tinea pedis such as untimely treatment, but other position sometimes, as cause the tinea manuum and tinea unguium etc., because itch and scratched, the secondary bacterial infection can cause severe complications sometimes.The traditional Chinese medical science claims that beriberi is " flaccidity of the lower limbs ".Prescriptions Worth Thousand Gold for Emergencies is rolled up 22 " pathogenic wind-toxic beriberi sides ": " so this sick sending out is first earlier from foot, because of being swelling shank, the time people number be beriberi.Dark Shi Yun: foot weak person, promptly its justice is also ".
Beriberi is a kind of extremely common fungal infection dermatoses.The people of 70-80% has beriberi among the adult, just the weight difference.Be everlasting and increase the weight of summer, alleviate winter, also has the people not heal all the year round.Medically usually beriberi is divided three types: erosive type, vesicle type, keratinization type beriberi.
Treatment does not still have specific medicament clinically at present.Mostly the clinical treatment method that is used for tinea pedis is to adopt skin surface to smear antiinflammatory, sterilization, antipruritic ointment, and its therapeutic effect is all not really desirable, is still the unsolved difficult problem of medical circle at present.
Summary of the invention
The purpose of this invention is to provide a kind of therapeutic effect good, be free from side effects, from toxin expelling, anti-inflammation and sterilization, reparation, reactivate Skin Cell, promote the epidermis microcirculation to make the skin exquisiteness, reach the compound spirit of the treatment tinea pedis for the treatment of both the principal and secondary aspects of a disease effect.
The compound spirit of treatment tinea pedis of the present invention is made up of following materials of weight proportions:
Contain in per 100 parts ethanol: potassium permanganate 10-20 part, salicylic acid 10-20 part, vinegar 10-20 part, Herba Sidae Rhombifoliae 8-15 part, fibroferritum 8-15 part, Cortex Phellodendri 8-15 part, Os Sepiae 8-15 part, Cortex Dictamni 8-15 part, Fructus Cnidii 8-15 part, Fructus Gleditsia 8-15 part, Herba Portulacae 6-10 part, Rhizoma Acori Graminei 6-10 part, Herba Plantaginis 6-10 part, Flos Impatientis 6-10 part, Fructus Mume 6-10 part, Cortex Meliae 6-10 part, Rhizoma Atractylodis 6-10 part, Radix Sophorae Flavescentis 4-8 part, Flos Caryophylli 4-8 part, Fructus Evodiae 4-8 part, Borneolum Syntheticum 4-8 part, sulfur 4-8 part, Herba Xanthii 4-8 part, Cortex Pseudolaricis 4-8 part, Radix Gentianae 4-8 part, Nidus Vespae 4-8 part, Ramulus Uncariae Cum Uncis 4-8 part, Realgar 1-5 part, Camphora 1-5 part, Calomelas 1-5 part, Calamina 1-5 part, Lithargyrum 1-5 part, Semen Phaseoli 1-5 part, Oleum menthae 8-15 part;
Preparation method:
1, it is standby by formula proportion Herba Sidae Rhombifoliae, fibroferritum, Cortex Phellodendri, Os Sepiae, Cortex Dictamni, Fructus Cnidii, Fructus Gleditsia, Herba Portulacae, Rhizoma Acori Graminei, Herba Plantaginis, Flos Impatientis, Fructus Mume, Cortex Meliae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Flos Caryophylli, Fructus Evodiae, sulfur, Herba Xanthii, Cortex Pseudolaricis, Radix Gentianae, Nidus Vespae, Ramulus Uncariae Cum Uncis, Realgar, Camphora, Calamina, Lithargyrum, Semen Phaseoli to be ground into 300-400 purpose fine powder;
2, stir adding the fine powder that potassium permanganate, salicylic acid, vinegar adds after the pulverizing then in the ethanol by formula proportion, being to add Borneolum Syntheticum blends, add Oleum menthae at last and stir, with ultrasound wave homogenize 10-30 minute, packing was finished product under 0-10 ℃ of temperature.
Usage: put every day 3-4 time, logotype 2-4 week outward on the skin.Indication: various types of tinea.
The herbal pharmacology of the present invention and the property of medicine:
Vinegar: [nature and flavor] are bitter, temperature.1. " not Lu ": " sour in the mouth, temperature, nontoxic." 2. " book on Chinese herbal medicine covers bamboo fish trap ": " acid is sweet, temperature." 3. " detailed outline ": " is bitter, and temperature is nontoxic." [return through] goes into liver, stomach warp.1. " Thunder God is concocted the property of medicine and is separated ": " go into Liver Channel." 2. " book on Chinese herbal medicine is newly organized ": " goes into stomach, spleen, large intestine, walks liver especially." 3. " book on Chinese herbal medicine is through separating ": " goes into the Gallbladder Channel of Foot-Shaoyang, liver channel of foot-Jueyin." [function cures mainly] dissipating blood stasis, hemostasis, detoxifcation, parasite killing.Bruise after managing property, the mass beside the umbilicus lump in the abdomen, jaundice, yellowish perspiration is spitted blood, epistaxis, the stool hematochezia, pudendal pruritus, the carbuncle skin ulcer is swollen.Separate flesh of fish dish poison.1. " not Lu ": ' subduing inflammation, aproll gas, pathogenic toxin killing." 2. " a thousand pieces of gold dietetic therapy ": " controls blood fortune." 3. supplement to the Herbal: " removing blood stasis fortune is removed disease and determined hard long-pendingly, helps digestion, and is vicious extremely, broken stagnation of QI, sour water phlegm retention in the heart.Married woman and trauma after " 4. " Japan hanako materia medica ": " manages property, and incised wound blood fortune; Therapeutic method to keep the adverse QI flowing downwards relieving restlessness, broken crux.It is pained to control the married woman, helps all efficacy of a drug, kills all flesh of fish dish poison." 5. amplification on Canon of Materia Medica: " beneficial blood." 6. " Treatise on Febrile Disease with Notes ": " holds back the pharynx skin ulcer." 7. " detailed outline ": " dissipating blood stasis blood.Harness the Yellow River subcutaneous ulcer, yellowish perspiration." 8. essentials of Matea Medica: " dissipating blood stasis, detoxifcation, the therapeutic method to keep the adverse QI flowing downwards helps digestion, appetizing gas." 9. " the medical center bun is wanted ": " eliminating pathogen in the liver is got into the frame of mind for work.Control soldier's dusk, the dream of keeping alert while in bed; Tonifying the lung, pronunciation sound; Kill all poison of worm for fishing, the volt ascarid." 10. " can cure mirror approximately ": " controls the sliding dysentery of intestinal.(11) " book on Chinese herbal medicine is new again ": " give birth to all poison that can disappear the row dampness; System is with can declaring sun, but suppressing the hyperactive liver, astringing QI town wind, diffusing evil diaphoresis.' (12) " occupying the diet spectrum " with breath: " and appetizing, nourishing the liver, strong muscle, warm bone is sobered up, and helps digestion, and the therapeutic method to keep the adverse QI flowing downwards exorcises evil spirits, and separates all poison of fish Eriocheir sinensis aquatic animals." (13) " modern practical Chinese medicine ": " is used for the night sweat of tuberculosis, is Antiperspirant; The enterorrhagia of typhoid fever is hemorrhage again.
Herba Sidae Rhombifoliae: [nature and flavor] Gan Xin, cold.1. " Guangxi Chinese medicinal herbal ": it is little sour and astringent, cool in nature, nontoxic to distinguish the flavor of.2. " Guangdong Chinese medicine ": sweet, light.3. Guangzhou army " Chinese herbal medicine handbook: Gan Xin commonly used, cold.[return through] " Quanzhou book on Chinese herbal medicine ": go into the heart, liver, lung, all warps of intestine and small intestine.[function cures mainly-Herba Sidae Rhombifoliae effect] clearing away heat-damp and promoting diuresis, the evacuation of pus of invigorating blood circulation.Control influenza, flu, tonsillitis, dysentery, enteritis, jaundice, hemorrhoidal bleeding is spitted blood the carbuncle furuncle.1. " Guangxi Chinese medicinal herbal ": refrigerant drawing out pus by applying a plaster to the affected part, detumescence and apocenosis.Leaf: apply furuncle, furuncle.2. " Quanzhou book on Chinese herbal medicine ": the heat clearing away dissipating blood stasis, cooling blood for hemostasis is controlled the perianal abscess obstinate disease, hematochezia.3. Guangzhou army
" Chinese herbal medicine handbook commonly used): dispelling wind to relieve the exterior syndrome, dissipating blood stasis is drawn out pus by applying a plaster to the affected part.Control influenza, flu, tonsillitis, enteritis, bacillary dysentery, panaris furuncle.4. Guangzhou air force " Chinese herbal medicine handbook commonly used: clearing away heat-damp and promoting diuresis, evacuation of pus granulation promoting.The subcutaneous ulcer of harnessing the Yellow River, malaria, suppuration inflammation.
Fibroferritum: [nature and flavor] " Haiyao Bencao, Oversea Materia Medica ": " salty in the mouth is sour and astringent, and is poisonous." [function cures mainly] controls hemorrhoid complicated by anal fistula, malignant boil, scabies.1. Tang Materia Medica: " treat skin ulcer raw meat." 2. " Haiyao Bencao, Oversea Materia Medica ": " main pheasant fistula hemorrhoid, diseases such as malignant boil scabies." 3. Li Gao: " Zhi Yangming wind heat is had a toothache.″
Cortex Phellodendri: [meridian distribution of property and flavor] hardship, cold.Return kidney, urinary bladder channel.[function cures mainly] heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.
Os Sepiae: [meridian distribution of property and flavor] salty in the mouth, puckery, warm in nature.Return liver, kidney channel.[function cures mainly] astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness is held back skin ulcer.Cure mainly haematemesis, hematemesis, metrorrhagia is had blood in stool, epistaxis, wound hemorrhage; The emission and spermatorrhea of instability of kidney QI, leucorrhea with red and white discharge; It is noisy to have a stomachache, belch pantothenic acid; Eczema ulcer.
Cortex Dictamni: [meridian distribution of property and flavor] bitter cold, go into spleen, the stomach warp.[function] heat-clearing and toxic substances removing, expelling wind and removing dampness.Be used for diseases such as damp and hot sore, rubella, scabies, skin scratch, arthralgia chiefly caused by damp pathogen, jaundice.
Fructus Cnidii: [nature and flavor] temperature, acrid in the mouth, hardship.[function cures mainly] warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Fructus Gleditsia: [nature and flavor] are warm in nature, acrid in the mouth.[function cures mainly] detumescence poison holding, evacuation of pus, parasite killing.Be used for carbuncle from the beginning of or pusization do not burst; External treatment scabies leprosy.
Herba Portulacae: [meridian distribution of property and flavor] acid, cold.Return liver, large intestine channel.[function cures mainly] is applicable to dysentery (it is half-dried partly rare to defecate), heat-clearing and toxic substances removing, cooling blood for hemostasis.Be used for toxic-heat and blood stasis, the carbuncle furuncle, eczema, erysipelas, snake bite and insect sting is had blood in stool, hemorrhoidal bleeding, metrostaxis.Modern times are used for the treatment of enteritis, acute arthritis, cystitis, urethritis, anusitis, bleeding hemorrhoids etc. mostly.Collective Notes to the Canon of Materia medica " Bencao Tujing " is come from textual criticism: Herba Portulacae, have another name called five elements' grass, and with its leaf green grass or young crops, obstruct redly, brightly yellowish, root is white, and son is deceived also.Cure mainly: the pyretic toxicity dysentery; Pyretic stranguria; Urine retention; Leucorrhea with red and white discharge; Metrorrhagia; Hemorrhoidal bleeding; Skin infection carbuncle furuncle; Erysipelas; Scrofula; Exudative dermatitis; Bald in vain.. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": QI invigorating, clearing away summer-heat heat, the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, intestine moistening, removing food stagnancy stagnates, and parasite killing is treated the skin ulcer congestion and swelling pain.
Rhizoma Acori Graminei: [nature and flavor] are warm in nature, acrid in the mouth, hardship.[function cures mainly] can dirtyly have one's ideas straightened out for warding off, and a surname's gas is by expectorant, detoxifcation, parasite killing.Control demented, infantile convulsion, coma due to phlegm syncope, anemofrigid-damp arthralgia, mouthful fulminant dysentery of keeping silent, external application carbuncle scabies.Have one's ideas straightened out, reduce phlegm, be good for the stomach.Be used for epilepsy, expectorant febrile convulsion, vexed, the chronic bronchitis of breast abdominal distention.
Herba Plantaginis: [nature and flavor and function] is sweet, and be cold, returns the hands sun, Yangming Channel.Diuretic, heat clearing away makes eye bright, and eliminates the phlegm, and is used for urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, jaundice, edema, hematodiarrhoea is had loose bowels, epistaxis, conjunctival congestion and swelling pain, laryngalgia, cough, skin ulcer.
Flos Impatientis: [nature and flavor] are arduous, temperature.1. herbal for Relief of Famines: " leaf: bitter in the mouth is little puckery.2. " detailed outline ": " leaf: bitter sweet suffering, slightly poisonous." 3. " florilegium ": " leaf: sweet, temperature, nontoxic." [function cures mainly] dispels the wind, and invigorates blood circulation detumescence, pain relieving.Control joint rheumatalgia, traumatic injury, scrofula carbuncle is treated skin ulcer.
Fructus Mume: [meridian distribution of property and flavor] acid, puckery, flat.Return liver, spleen, lung, large intestine channel.[function cures mainly] antidiarrheal dysentery, cough-relieving, relieving colic caused by ascaris promotes the production of body fluid, and hemostasis is astringed the lung, and astringing intestine to stop diarrhea is used for chronic cough of deficiency lung, the chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
Cortex Meliae: [nature and flavor] are cold in nature, bitter in the mouth.Tinea is treated in [function cures mainly] anthelmintic.Be used for ascarid enterobiasis, abdominal pain due to worm stagnation; External treatment scabies pruritus
Rhizoma Atractylodis: [nature and flavor] are warm in nature, acrid in the mouth, hardship, and [function] eliminating turbid pathogen with aromatics dispels the wind that it is dirty to ward off, and is drying damp and strengthening spleen, is applicable to that gastral cavilty is vexed, and the big loose stool of abdominal distention is soft, vomiting and nausea, extremity asthenia, seasonal epidemic pathogens flu, all diseases of abundant expectoration.
Radix Sophorae Flavescentis: hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Effect: heat clearing and damp drying, parasite killing, diuresis.Be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Flos Caryophylli: [meridian distribution of property and flavor] acrid in the mouth, sweet, hot in nature; Return spleen, stomach, kidney channel.[function] warming the stomach; Sending down the abnormal ascending QI; Wet kidney.[curing mainly]: control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.
Fructus Evodiae: warm in nature, acrid in the mouth, hardship, the function warming middle-JIAO to relieve pain, the dry temperature of regulating the flow of vital energy is applicable to abdominal distention, vomiting and diarrhoea, singultus acid regurgitation, headache, colic, menstrual pain.
Borneolum Syntheticum: [meridian distribution of property and flavor] acrid in the mouth, hardship are slightly cold; GUIXIN, spleen, the lung hydrocarbon.[function] refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
Sulfur: [meridian distribution of property and flavor]: acid, heat, poisonous.1. " herbal classic ": " sour in the mouth, temperature." 2. " WU Pu Bencao ": " legendary god of farming, Yellow Emperor, a legendary ruler, Thunder God: salty, poisonous.Doctor and, Bian Que: nontoxic." 3. " not Lu ": " and big heat, poisonous." 4. " property of medicine opinion ": " and sweet in the mouth, very toxic." go into kidney, spleen channel.1. " Thunder God is concocted the property of medicine and is separated ": " go into gate of vitality's warp." 2. " Bencao Jingshu ": " go into meridian of Hand-JUE YIN." 3. " jade is seized medicine and is separated ": " go into spleen of Foot-Taiyin, kidney meridian, liver channel of foot-Jueyin." [function]: tonifying YANG, parasite killing; Control sexual impotence, deficiency and coldness dysentery, stool constipation due to accumulation of pathogenic cold; Scabies is controlled in external, eczema, impetigo.
Herba Xanthii: [meridian distribution of property and flavor] is hot, bitter, and temperature is slightly poisonous, returns lung meridian.[curing mainly] flu; Wind syndrome of head; Dizzy; Nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery, wind and heat eliminating, the detoxifcation parasite killing.The arthralgia chiefly caused by damp pathogen contracture.
Cortex Pseudolaricis: [nature and flavor] Xin Wen, poisonous, [function] killing parasites for relieving itching.Be used for the skin scabies.
Radix Gentianae: [meridian distribution of property and flavor] hardship, cold.Return liver, gallbladder meridian.[function cures mainly] heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.Be used for jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms.
Nidus Vespae: [meridian distribution of property and flavor] is sweet, and be flat.Return the stomach warp.[function cures mainly] dispels the wind, merit poison, parasite killing, pain relieving, antiallergic.Be used for toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot, allergic constitution.
Ramulus Uncariae Cum Uncis: [meridian distribution of property and flavor] is sweet, cold.Return liver, pericardium channel.[function cures mainly] heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.It is dizzy to be used to have a headache, dysphoric cold, and infantile convulsion is twitched, pregnant eclamposia; Hypertension." detailed outline ": " the big number of people revolves dizzy, and suppressing liver-wind removes heat in the heart, and children's's infantile tic stomachache is sent out macule.
Realgar: [meridian distribution of property and flavor] suffering, temperature; Poisonous.Return liver, large intestine channel.Compendium of Material Medica: take by force, put down, tremble with fear, poisonous.[function cures mainly] detoxifcation parasite killing, removing dampness and eliminating phlegm, preventing the attack (or recurrence) of malaria.Be used for the carbuncle furuncle, snake bite and insect sting, abdominal pain due to worm stagnation, infantile convulsion, malaria.
Camphora: [meridian distribution of property and flavor] suffering, temperature.[function cures mainly] sensible ward off dirty, warming middle-JIAO to relieve pain, dampness removing parasite killing.Be used for cold-damp and vomit and diarrhoea stomach abdomen pain; External is controlled scabies, tinea, dental caries and is had a pain.
Calomelas: [nature and flavor] are hot, cold, poisonous, go into liver, kidney channel; [effect] counteracting toxic substances, diuretic, relieving constipation, control scabies, scrofula, syphilis, primary sore, skin ulcer, edema, tympanites, defecation is closed.
Calamina: [nature and flavor with return through] are sweet, and are flat.Return the stomach warp.[function with cure mainly] detoxifcation improving acuity of vision and removing nebula, the antipruritic skin ulcer of holding back of removing dampness.Be used for conjunctival congestion and swelling pain, marginal blepharitis, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, pus is dripping, eczema, skin pruritus.
The Lithargyrum: [meridian distribution of property and flavor] is salty, hot, flat, poisonous; Go into liver, spleen channel; [effect] detumescence, parasite killing, convergence are anticorrosion, eliminating phlegm down to arrest convulsion, through test to multiple pathogenic dermatophytes, inhibitory action is in various degree arranged, can shrink the blood vessel at mucosa and ulcer place, secretion is reduced, and effect such as protecting from infection of antiinflammatory is arranged.
Semen Phaseoli: [meridian distribution of property and flavor] property is flat, sweet in the mouth, acid.Go into the heart, small intestine meridian.[function cures mainly] wards off pestilence, the difficulty of managing property, following afterbirth, promoting lactation, the diuretic kind that disappears, removing toxic substances and promoting pus discharge.Be used for edema distension, beriberi edema, jaundice dark coloured urine, rheumatism pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
The compound spirit of treatment tinea pedis of the present invention is made up of following materials of weight proportions:
Contain in per 100 parts ethanol: potassium permanganate 13-18 part, salicylic acid 13-18 part, vinegar 13-18 part, Herba Sidae Rhombifoliae 9-13 part, fibroferritum 9-13 part, Cortex Phellodendri 9-13 part, Os Sepiae 9-13 part, Cortex Dictamni 9-13 part, Fructus Cnidii 9-13 part, Fructus Gleditsia 9-13 part, Herba Portulacae 7-9 part, Rhizoma Acori Graminei 7-9 part, Herba Plantaginis 7-9 part, Flos Impatientis 7-9 part, Fructus Mume 7-9 part, Cortex Meliae 7-9 part, Rhizoma Atractylodis 7-9 part, Radix Sophorae Flavescentis 5-7 part, Flos Caryophylli 5-7 part, Fructus Evodiae 5-7 part, Borneolum Syntheticum 5-7 part, sulfur 5-7 part, Herba Xanthii 5-7 part, Cortex Pseudolaricis 5-7 part, Radix Gentianae 5-7 part, Nidus Vespae 5-7 part, Ramulus Uncariae Cum Uncis 5-7 part, Realgar 2-4 part, Camphora 2-4 part, Calomelas 2-4 part, Calamina 2-4 part, Lithargyrum 2-4 part, Semen Phaseoli 2-4 part, Oleum menthae 9-13 part;
The compound spirit of treatment tinea pedis of the present invention is made up of following materials of weight proportions:
Contain in per 100 parts ethanol: 15 parts in potassium permanganate, 15 parts of salicylic acid, 15 parts of vinegar, 12 parts of Herba Sidae Rhombifoliaes, 12 parts of fibroferritum, 12 parts of Cortex Phellodendris, 12 parts of Os Sepiae, 12 parts of Cortex Dictamnis, 12 parts of Fructus Cnidiis, 12 parts of Fructus Gleditsia, 8 parts of Herba Portulacaes, 8 parts of Rhizoma Acori Gramineis, 8 parts of Herba Plantaginiss, 8 parts of Flos Impatientiss, 8 parts of Fructus Mumes, 8 parts of Cortex Meliaees, 8 parts of Rhizoma Atractylodis, 6 parts of Radix Sophorae Flavescentiss, 6 parts of Flos Caryophyllis, 6 parts of Fructus Evodiaes, 6 parts of Borneolum Syntheticums, 6 parts in sulfur, 6 parts of Herba Xanthiis, 6 parts of Cortex Pseudolaricis, 6 parts of Radix Gentianaes, 6 parts in Nidus Vespae, 6 parts of Ramulus Uncariae Cum Uncis, 3 parts of Realgars, 3 parts of Camphoras, 3 parts of Calomelass, 3 parts of Calaminas, 3 parts of Lithargyrums, 3 parts of Semen Phaseolis, 12 parts of Oleum menthae;
The specific embodiment
Embodiment 1:
Prescription: contain in the ethanol of every 100g: potassium permanganate 10g, salicylic acid 10g, vinegar 10g, Herba Sidae Rhombifoliae 8g, fibroferritum 8g, Cortex Phellodendri 8g, Os Sepiae 8g, Cortex Dictamni 8g, Fructus Cnidii 8g, Fructus Gleditsia 8g, Herba Portulacae 6g, Rhizoma Acori Graminei 6g, Herba Plantaginis 6g, Flos Impatientis 6g, Fructus Mume 6g, Cortex Meliae 6g, Rhizoma Atractylodis 6g, Radix Sophorae Flavescentis 4g, Flos Caryophylli 4g, Fructus Evodiae 4g, Borneolum Syntheticum 4g, sulfur 4g, Herba Xanthii 4g, Cortex Pseudolaricis 4g, Radix Gentianae 4g, Nidus Vespae 4g, Ramulus Uncariae Cum Uncis 4g, Realgar 1g, Camphora 1g, Calomelas 1g, Calamina 1g, Lithargyrum g, Semen Phaseoli 1g, Oleum menthae 8g;
Preparation method:
1, it is standby by formula proportion Herba Sidae Rhombifoliae, fibroferritum, Cortex Phellodendri, Os Sepiae, Cortex Dictamni, Fructus Cnidii, Fructus Gleditsia, Herba Portulacae, Rhizoma Acori Graminei, Herba Plantaginis, Flos Impatientis, Fructus Mume, Cortex Meliae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Flos Caryophylli, Fructus Evodiae, sulfur, Herba Xanthii, Cortex Pseudolaricis, Radix Gentianae, Nidus Vespae, Ramulus Uncariae Cum Uncis, Realgar, Camphora, Calamina, Lithargyrum, Semen Phaseoli to be ground into 300-400 purpose fine powder;
2, stir adding the fine powder that potassium permanganate, salicylic acid, vinegar adds after the pulverizing then in the ethanol by formula proportion, being to add Borneolum Syntheticum blends, add Oleum menthae at last and stir, with ultrasound wave homogenize 10-30 minute, packing was finished product under 0-10 ℃ of temperature.
Usage: put every day 3-4 time, (7 days/one course of treatment) logotype 2-4 week outward on the skin.Indication: various types of tinea.
Embodiment 2:
Prescription: contain in the ethanol of every 100g: potassium permanganate 13g, salicylic acid 13g, vinegar 13g, Herba Sidae Rhombifoliae 9g, fibroferritum 9g, Cortex Phellodendri 9g, Os Sepiae 9g, Cortex Dictamni 9g, Fructus Cnidii 9g, Fructus Gleditsia 9g, Herba Portulacae 7g, Rhizoma Acori Graminei 7g, Herba Plantaginis 7g, Flos Impatientis 7g, Fructus Mume 7g, Cortex Meliae 7g, Rhizoma Atractylodis 7g, Radix Sophorae Flavescentis 5g, Flos Caryophylli 5g, Fructus Evodiae 5g, Borneolum Syntheticum 5g, sulfur 5g, Herba Xanthii 5g, Cortex Pseudolaricis 5g, Radix Gentianae 5g, Nidus Vespae 5g, Ramulus Uncariae Cum Uncis 5g, Realgar 2g, Camphora 2g, Calomelas 2g, Calamina 2g, Lithargyrum 2g, Semen Phaseoli 2g, Oleum menthae 9g;
Preparation method is identical with embodiment 1 with usage.
Embodiment 3:
Prescription: contain in the ethanol of every 100g: potassium permanganate 15g, salicylic acid 15g, vinegar 15g, Herba Sidae Rhombifoliae 12g, fibroferritum 12g, Cortex Phellodendri 12g, Os Sepiae 12g, Cortex Dictamni 12g, Fructus Cnidii 12g, Fructus Gleditsia 12g, Herba Portulacae 8g, Rhizoma Acori Graminei 8g, Herba Plantaginis 8g, Flos Impatientis 8g, Fructus Mume 8g, Cortex Meliae 8g, Rhizoma Atractylodis 8g, Radix Sophorae Flavescentis 6g, Flos Caryophylli 6g, Fructus Evodiae 6g, Borneolum Syntheticum 6g, sulfur 6g, Herba Xanthii 6g, Cortex Pseudolaricis 6g, Radix Gentianae 6g, Nidus Vespae 6g, Ramulus Uncariae Cum Uncis 6g, Realgar 3g, Camphora 3g, Calomelas 3g, Calamina 3g, Lithargyrum 3g, Semen Phaseoli 3g, Oleum menthae 12g;
Preparation method is identical with embodiment 1 with usage.
Embodiment 4:
Prescription: contain in the ethanol of every 100g: potassium permanganate 18g, salicylic acid 18g, vinegar 18g, Herba Sidae Rhombifoliae 13g, fibroferritum 13g, Cortex Phellodendri 13g, Os Sepiae 13g, Cortex Dictamni 13g, Fructus Cnidii 13g, Fructus Gleditsia 13g, Herba Portulacae 9g, Rhizoma Acori Graminei 9g, Herba Plantaginis 9g, Flos Impatientis 9g, Fructus Mume 9g, Cortex Meliae 9g, Rhizoma Atractylodis 9g, Radix Sophorae Flavescentis 7g, Flos Caryophylli 7g, Fructus Evodiae 7g, Borneolum Syntheticum 7g, sulfur 7g, Herba Xanthii 7g, Cortex Pseudolaricis 7g, Radix Gentianae 7g, Nidus Vespae 7g, Ramulus Uncariae Cum Uncis 7g, Realgar 4g, Camphora 4g, Calomelas 4g, Calamina 4g, Lithargyrum 4g, Semen Phaseoli 4g, Oleum menthae 18g;
Preparation method is identical with embodiment 1 with usage.
Embodiment 5:
Prescription: contain in the ethanol of every 100g: potassium permanganate 20g, salicylic acid 20g, vinegar 20g, Herba Sidae Rhombifoliae 15g, fibroferritum 15g, Cortex Phellodendri 15g, Os Sepiae 15g, Cortex Dictamni 15g, Fructus Cnidii 15g, Fructus Gleditsia 15g, Herba Portulacae 10g, Rhizoma Acori Graminei 10g, Herba Plantaginis 10g, Flos Impatientis 10g, Fructus Mume 10g, Cortex Meliae 10g, Rhizoma Atractylodis 10g, Radix Sophorae Flavescentis 8g, Flos Caryophylli 8g, Fructus Evodiae 8g, Borneolum Syntheticum 8g, sulfur 8g, Herba Xanthii 8g, Cortex Pseudolaricis 8g, Radix Gentianae 8g, Nidus Vespae 8g, Ramulus Uncariae Cum Uncis 8g, Realgar 5, Camphora 5g, Calomelas 5g, Calamina 5g, Lithargyrum 5g, Semen Phaseoli 5g, Oleum menthae 15g;
Preparation method is identical with embodiment 1 with usage.
The invention has the beneficial effects as follows: help the performance of the physiological function of skin; Existing therapeutical effect has the effect of protection skin again, has multiple therapeutic effect than simple application ethanol and potassium permanganate, reduced the drying of skin, nervous sense in the use, and zest is little, and the patient is easy to accept, and has a extensive future.Use effectively kill bacteria of potassium permanganate in the prescription, salicylic acid can kill bacteria, fungus, virus, ameba etc., can be used to treat many bacillary, fungoids, dermatosis such as viral.Influence its chemotaxis, influence the statement of some cytokine, the generating process of inflammation-inhibiting has dual antiinflammatory action.Vinegar can increase Mucocutaneous metabolism and suppress anaphylaxis, promotes the growth of cell.Select for use Chinese herbal medicine all pointed among the we, have effects such as antibiotic, antiinflammatory, virus killing, toxin expelling, evacuation of pus, the sebum in can the dissolved dilution follicular orifice is beneficial to the discharge of exfoliative cyte, reduce the chance of secondary infection, simultaneously skin is had the effect of preserving moisture, moistening and prolonging local drug effect.Borneolum Syntheticum and Oleum menthae have the effect of refreshing and detoxicating, skin protection, finally reduce the formation of antibacterial and struvite fungus, pustule.
Treatment tinea pedis observation of curative effect
Tinea pedis is the commonly encountered diseases of department of dermatologry, and we adopted self-control tinea pedis preparation for treating tinea pedis case 500 many cases in 2004-2009, obtain good result, now were summarized as follows.Typical clinical case inclusion criteria:
Inclusion criteria: have typical clinical manifestation, meet the diagnostic criteria of II level acne vulgaris 1, do not do any Drug therapy in January, there is not the other diseases of merging.
Rejecting standard: to this product allergy sufferers; Prolonged application corticosteroid hormone person; Symptomatic tinea pedis; Therapy discontinued and can not further consultation person.
MethodsThe cases enrolled 60 examples, wherein male's 38 examples. women's 22 examples, minimal ages 18 years old, maximum 63 years old, 34 years old mean age, vesicle type 31 examples wherein, erosive type 20 examples, keratinization type 9 examples, patient is ill the longest more than 3 years, more than a year the shortest to consultation time.Clinical symptoms: the part has that the phlysis, the erosion that are dispersed in are oozed out, pain, swelling, very itch, dysfunction etc.
Model case
Case 1:
Mrs Zhao, suffer from beriberi for many years, it all is useful at that time once using a lot of ointment, liquid medicine, just violated again after a stage, little bubble and area have often occurred and constantly enlarge, foot is done decortication, toe has tinea unguium at present, the skin color of foot dark (resembling like cicatrix) uses medicine two all symptom complete obiterations of the present invention, not recurrence in 3 years.
Case 2:
Mr. Xu, beriberi is that wife is infectious, longer a lot of blisters are itched very much on the toe of being everlasting.Often blister is squeezed and break, smear the ointment of daktarin and so on then, can support several days like this, but often be revivable.Beriberi liquor, Compound Flavescent Sophora and Salicylic Acid Powder, also have various ointment all use all over, still as usual now, and the area of long blister uses medicine three all symptom complete obiterations of the present invention as increasing, recurs so far.
Case 3:
Liu XX, the foot of being engaged in agriculture seam decortication and subcutaneous a lot of yellow vesicle are arranged, toenail thickens suddenly when examining, also has rough pitting on the toenail face, toenail and begin to slough off the toenail gross distortion from the top, use medicine two all symptom complete obiterations of the present invention, so far not recurrence.
Case 4:
Opening XX2007 has suffered from ' tinea pedis ', decortication is got blister, and very itches foot odor, medication always for a long time, application method: wipe, wash, steep, smear, but effect is little.Use medicine of the present invention symptom complete obiteration in 7 days, so far not recurrence.
Case 5:
Chen, man, 28 years old. the private workman of factory in Zhangjiakou.Before 3 years, be diagnosed as beriberi, go to a doctor, have a medical check-up: see between both feet the 5th and four toes, between the 3rd and two toes the red phlysis that is dispersed in arranged and have weak yellow liquid to ooze out.Local swelling is with erosion, and readme is very itched unbearably.Use compound spirit, be applied to the affected part, every day twice, 4 drug withdrawals course of treatment of logotype outside being stained with cotton swab.Clinical symptoms and Signs complete obiteration, local skin is as excellent as before and fully recover.So far not recurrence.
Case 6:
The king so-and-so, man, 45 years old. Zhangjiakou Principal of School.Go to a doctor because of concurrent serious fungal infection, show as between heating, toe, the obvious swelling of instep, more yellowish pus is arranged, the inguinal lymph enlargement between pain, toe.Patient very itches unbearably, suffers untold misery.Process use tinea pedis tincture of the present invention is applied to the affected part outside being stained with cotton swab, anti-inflammatory treatment, control infection, and every day twice, recurrence is not followed up a case by regular visits in logotype drug withdrawal 4 courses of treatment recovery from illness.
Case 7:
Year surplus Yuan XX trouble beriberi 10, use multiple beriberic external medication, certain curative effect is arranged, but recurrence every year, tincture of the present invention is used in healing, treats and takes effect in five days, cures in 10 days, recurs so far.
Case 8:
Open XX because of domestic pets, three mouthfuls of infected upward funguses of the whole family, vitamin B1 deficiency is serious, existing 10 years, once used multiple beriberic external medication, certain curative effect is arranged, but recurrence is not every year cured, use tincture of the present invention, treat and took effect in 15 days, cure 3 courses of treatment, so far not recurrence.
Medication and observational technique: dip in cotton swab and to get the tincture for preparing, evenly be applied to the affected part, area is slightly larger than skin lesion, early, middle and late each once, one month course of treatment.Before treatment, 1 week of treatment back, 2 weeks, 3 all and 4 weeks carried out clinical score.The method of scoring be with clinical manifestation inflammation pimple, pus kitchen by not having-0, gently-1, in-2, heavy by-3, adding up after the scoring both is clinical score; Score * 100% before treatment back clinical improvements rate=(score before the treatment-treatment back score)/treatment.
Efficacy determination: adopt 4 grade standards
Produce effects: treat 4 courses of treatment through compound recipe tinea pedis tincture, clinical symptoms and sign disappear substantially, and local skin is intact.
Effectively: treat 4 courses of treatment through compound recipe tinea pedis tincture, clinical symptoms and sign are obviously improved, and the local skin infringement obviously alleviates.
Invalid: through 4 courses of treatment of compound recipe tinea pedis tincture treatment, clinical symptoms and sign do not have obvious improvement, and local pain, swelling do not have obviously and alleviates.
Recovery from illness clinical improvements rate 〉=95%; Produce effects clinical improvements rate<95%, 〉=60%;
Effective clinical improvements rate<60%, 〉=20%; Invalid clinical improvements rate<20%;
Recovery from illness adds produce effects and adds up to effective percentage.
Therapeutic outcome sees Table
Figure G2009100148455D00111
Side effect is observed
This group skin erythema occurs after 5 examples (8.3%) patient medication is arranged, excitement, but unprocessed spontaneous remission, and all therapy discontinued not finished until the course of treatment.

Claims (3)

1. compound spirit for the treatment of tinea pedis is characterized in that being made up of following materials of weight proportions:
Contain in per 100 parts ethanol: potassium permanganate 10-20 part, salicylic acid 10-20 part, vinegar 10-20 part, Herba Sidae Rhombifoliae 8-15 part, fibroferritum 8-15 part, Cortex Phellodendri 8-15 part, Os Sepiae 8-15 part, Cortex Dictamni 8-15 part, Fructus Cnidii 8-15 part, Fructus Gleditsia 8-15 part, Herba Portulacae 6-10 part, Rhizoma Acori Graminei 6-10 part, Herba Plantaginis 6-10 part, Flos Impatientis 6-10 part, Fructus Mume 6-10 part, Cortex Meliae 6-10 part, Rhizoma Atractylodis 6-10 part, Radix Sophorae Flavescentis 4-8 part, Flos Caryophylli 4-8 part, Fructus Evodiae 4-8 part, Borneolum Syntheticum 4-8 part, sulfur 4-8 part, Herba Xanthii 4-8 part, Cortex Pseudolaricis 4-8 part, Radix Gentianae 4-8 part, Nidus Vespae 4-8 part, Ramulus Uncariae Cum Uncis 4-8 part, Realgar 1-5 part, Camphora 1-5 part, Calomelas 1-5 part, Calamina 1-5 part, Lithargyrum 1-5 part, Semen Phaseoli 1-5 part, Oleum menthae 8-15 part; Preparation method is as follows:
(1) it is standby by formula proportion Herba Sidae Rhombifoliae, fibroferritum, Cortex Phellodendri, Os Sepiae, Cortex Dictamni, Fructus Cnidii, Fructus Gleditsia, Herba Portulacae, Rhizoma Acori Graminei, Herba Plantaginis, Flos Impatientis, Fructus Mume, Cortex Meliae, Rhizoma Atractylodis, Radix Sophorae Flavescentis, Flos Caryophylli, Fructus Evodiae, sulfur, Herba Xanthii, Cortex Pseudolaricis, Radix Gentianae, Nidus Vespae, Ramulus Uncariae Cum Uncis, Realgar, Camphora, Calamina, Calomelas, Lithargyrum, Semen Phaseoli to be ground into 300-400 purpose fine powder;
(2) stir adding the fine powder that potassium permanganate, salicylic acid, vinegar adds after the pulverizing then in the ethanol by formula proportion, add Borneolum Syntheticum, add Oleum menthae at last and stir, with ultrasound wave homogenize 10-30 minute, packing was finished product under 0-10 ℃ of temperature.
2. the compound spirit of treatment tinea pedis according to claim 1 is characterized in that, is made up of following materials of weight proportions:
Contain in per 100 parts ethanol: potassium permanganate 13-18 part, salicylic acid 13-18 part, vinegar 13-18 part, Herba Sidae Rhombifoliae 9-13 part, fibroferritum 9-13 part, Cortex Phellodendri 9-13 part, Os Sepiae 9-13 part, Cortex Dictamni 9-13 part, Fructus Cnidii 9-13 part, Fructus Gleditsia 9-13 part, Herba Portulacae 7-9 part, Rhizoma Acori Graminei 7-9 part, Herba Plantaginis 7-9 part, Flos Impatientis 7-9 part, Fructus Mume 7-9 part, Cortex Meliae 7-9 part, Rhizoma Atractylodis 7-9 part, Radix Sophorae Flavescentis 5-7 part, Flos Caryophylli 5-7 part, Fructus Evodiae 5-7 part, Borneolum Syntheticum 5-7 part, sulfur 5-7 part, Herba Xanthii 5-7 part, Cortex Pseudolaricis 5-7 part, Radix Gentianae 5-7 part, Nidus Vespae 5-7 part, Ramulus Uncariae Cum Uncis 5-7 part, Realgar 2-4 part, Camphora 2-4 part, Calomelas 2-4 part, Calamina 2-4 part, Lithargyrum 2-4 part, Semen Phaseoli 2-4 part, Oleum menthae 9-13 part.
3. the compound spirit of treatment tinea pedis according to claim 1 is characterized in that, is made up of following materials of weight proportions:
Contain in per 100 parts ethanol: 15 parts in potassium permanganate, 15 parts of salicylic acid, 15 parts of vinegar, 12 parts of Herba Sidae Rhombifoliaes, 12 parts of fibroferritum, 12 parts of Cortex Phellodendris, 12 parts of Os Sepiae, 12 parts of Cortex Dictamnis, 12 parts of Fructus Cnidiis, 12 parts of Fructus Gleditsia, 8 parts of Herba Portulacaes, 8 parts of Rhizoma Acori Gramineis, 8 parts of Herba Plantaginiss, 8 parts of Flos Impatientiss, 8 parts of Fructus Mumes, 8 parts of Cortex Meliaees, 8 parts of Rhizoma Atractylodis, 6 parts of Radix Sophorae Flavescentiss, 6 parts of Flos Caryophyllis, 6 parts of Fructus Evodiaes, 6 parts of Borneolum Syntheticums, 6 parts in sulfur, 6 parts of Herba Xanthiis, 6 parts of Cortex Pseudolaricis, 6 parts of Radix Gentianaes, 6 parts in Nidus Vespae, 6 parts of Ramulus Uncariae Cum Uncis, 3 parts of Realgars, 3 parts of Camphoras, 3 parts of Calomelass, 3 parts of Calaminas, 3 parts of Lithargyrums, 3 parts of Semen Phaseolis, 12 parts of Oleum menthae.
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CN102233005B (en) * 2011-06-30 2013-05-08 梁可可 Medicinal vinegar for treating fungal beriberi and preparation method thereof

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CN104491069B (en) * 2014-11-28 2017-09-05 中国人民解放军第二军医大学 A kind of traditional Chinese medicine for treating tinea pedis and its application
CN104621737B (en) * 2015-03-03 2016-05-11 宁波高新区苗姑养生科技有限公司 A kind of quilted stockings of preventing and treating onychomycosis
CN107853757A (en) * 2017-11-13 2018-03-30 曾志煌 A kind of comfortable wear-resistant healthcare silk stocking of ship type
CN112807399A (en) * 2021-03-04 2021-05-18 闫海波 A Chinese medicinal tincture for treating dermatoses, and its preparation method

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