KR20100079858A - The new medicine for skin disease composed of mineral and medical herbs - Google Patents

The new medicine for skin disease composed of mineral and medical herbs Download PDF

Info

Publication number
KR20100079858A
KR20100079858A KR1020080138443A KR20080138443A KR20100079858A KR 20100079858 A KR20100079858 A KR 20100079858A KR 1020080138443 A KR1020080138443 A KR 1020080138443A KR 20080138443 A KR20080138443 A KR 20080138443A KR 20100079858 A KR20100079858 A KR 20100079858A
Authority
KR
South Korea
Prior art keywords
skin
effect
mineral
mixture
natural mineral
Prior art date
Application number
KR1020080138443A
Other languages
Korean (ko)
Inventor
하태옥
Original Assignee
지에스씨 영농조합법인
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지에스씨 영농조합법인 filed Critical 지에스씨 영농조합법인
Priority to KR1020080138443A priority Critical patent/KR20100079858A/en
Publication of KR20100079858A publication Critical patent/KR20100079858A/en

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

PURPOSE: An external use formulation using natural mineral and medicinal herbs is provided to minimize side effects and maximize skin regeneration effect and pharmacological effect. CONSTITUTION: A therapeutic agent for dermatitis contains mineral mixture of germanium, glauberitum, calamina, elvan, lithargyrum, and talcum; medicinal herb mixture of angelicae dahuricae Radix, bupleuri Radix, Scutellariae Radix, coptidis Rhizoma, and wild ginseng; and walnut oil.

Description

천연광물과 한약재를 주원료로 한 피부질환 치료용 외용제{The new medicine for skin disease composed of mineral and medical herbs}External medicine for treating skin diseases mainly composed of natural minerals and herbal medicines {The new medicine for skin disease composed of mineral and medical herbs}

본 발명은 피부질환 치료용 외용제와 그 제조방법에 관한 것으로서, 특히 호르몬제와 화학적 약물을 포함하는 종래의 피부질환 치료제에 비하여 부작용을 최소화하고 아울러 아토피성 피부염을 비롯한 피부질환에 약리효과와 피부의 재생효과를 극대화하기 위하여 한의학적으로 효과가 제시된 천연광물과 한약재를 주원료로 한 피부질환치료제 및 그 제조방법을 제공하는 데 있다.The present invention relates to an external preparation for the treatment of skin diseases and a method of manufacturing the same, in particular, compared to conventional skin disease treatment agents including hormones and chemical drugs to minimize side effects and pharmacological effects and skin of skin diseases, including atopic dermatitis In order to maximize the regenerative effect, the present invention provides a therapeutic agent for the skin disease and its manufacturing method based on natural minerals and herbal medicines that have been shown to be oriental medicine.

근래에 들어 대표적인 피부질환 치료제에 있어서 아토피성 피부염이 급격히 증가하는 추세이다. 상기 아토피성 피부염은 여러 가지 원인으로 발병하는 것으로서 유전적 원인 이외에 스트레스와 혈류의 장애 또한 아토피성 피부염의 원인으로 제시되고 있다.In recent years, atopic dermatitis is rapidly increasing in typical skin disease treatments. The atopic dermatitis is caused by various causes, and in addition to the genetic cause, disorders of stress and blood flow have also been suggested as causes of atopic dermatitis.

한편, 상기와 같은 여러 원인으로 발생한다고 제시된 아토피성 피부염을 치료하고 증상을 완화하기 위하여 종래에 수많은 치료제가 제안되었으며 그 대부분이 서양의학의 관점에서 출발하여 항히스타민제 또는 부신피질 호르몬제가 주로 사용되고 있으나, 항히스타민제의 경우 비교적 안정적인 약물이지만 졸음, 발기부전, 녹내장, 두통, 체중증가, 심실성 부정맥과 같은 부작용이 보고된바 있고, 특히 스테로이드제의 경우에는 간경화, 고혈압, 당뇨병에 악영향을 미치며 인체내 항산화능력이 감소하는 등 부작용이 심각한 것으로 알려져 있다.On the other hand, a number of therapeutic agents have been proposed in the past to treat atopic dermatitis and alleviate the symptoms suggested to occur due to the various causes as described above, and most of them are antihistamine or corticosteroids, starting from the viewpoint of Western medicine. Antihistamines are relatively stable drugs, but side effects such as drowsiness, erectile dysfunction, glaucoma, headache, weight gain, and ventricular arrhythmias have been reported.In particular, steroids have an adverse effect on liver cirrhosis, hypertension, diabetes, Side effects are known to be serious, such as decreased ability.

따라서, 상기 종래의 호르몬 제재 및 화학적 약물을 포함하는 치료제는 그 부작용이 심각하여 안정적으로 사용할 수 없는 문제점이 있다.Therefore, the conventional therapeutic agent containing a hormonal agent and a chemical drug has a problem that its side effects are serious and cannot be used stably.

본 발명이 이루고자 하는 기술적 과제는, 상기의 종래기술에서의 단점을 해결하기 위하여, 한의학적으로 약리효과가 증명된 천연광물과 한약재의 약리효과를 이용하여 피부질환 치료용 외용제를 제공하여 호르몬 제재 및 화학적 약물에서 나타나는 부작용을 최소화하고 아토피와 같은 피부질환의 치료 뿐만 아니라 신체적인 항산화능력과 피부재생능력을 극대화 할 수 있는 피부질환 치료용 외용제와 그 제조방법을 제공하는 데 있다.The technical problem to be achieved by the present invention, in order to solve the disadvantages of the prior art, by using the pharmacological effect of natural minerals and herbal medicine that has been proven medicinal medicinal effect by providing an external preparation for skin disease treatment hormone preparation and chemical To minimize the side effects of drugs and to treat skin diseases such as atopy, as well as to provide an external preparation for the treatment of skin diseases that can maximize the physical antioxidant capacity and skin regeneration ability and a method of manufacturing the same.

본 발명은 상기의 기술적 과제를 해결하기 위하여, 천연광물로서 항산화작용과 피부염에 방부, 수렴, 보호작용을 하는 게르마늄과 신열(身熱)의 번만(煩滿)과 피중여화(皮中如化)를 주로 낫게 한다는 한수석(寒水石)과 피부습진과 만성피부궤양과 가려움증에 효과가 있는 노감석(爐甘石)과 습진과 피부염에 효과가 있고 새 조직에 신생력을 도와주는 맥반석(麥飯石)과 피부의 습기를 제거시키면서 부패방지와 궤양치료에 효과를 가지고 소염과 해열작용의 효과를 가진 밀타승(密陀僧)과 피 부 윤활 작용과 건조 효과가 있어서 피부 보호제로 많이 응용되는 활석(滑石)의 유효성분과 한약재로서 진통효과와 피부궤양에 효과가 있는 백지(白芷)와 해열, 진통에 효과를 가지는 시호(柴胡)와 해열과 소염제로서 효과를 가지는 황금(黃芩)과 건위, 진정, 소염, 항균등의 효능이 있는 황련(黃連)과 성질이 따뜻하고 입의 갈증해소와 피부의 본래기능촉진과 점막의 소염작용에 효과를 보이는 산삼(山蔘)의 유효성분과 우수한 피부관리 효과와 약간의 살균력을 가진 호도유를 조성물로 하는 피부질환 치료용 외용제에 의해 달성될 수 있다.The present invention is to solve the above technical problem, as a natural mineral, anti-oxidation and dermatitis in the preservation, convergence, protective effect of the germ and heat of fever (피 煩 滿) and blood aging (皮 中 如 化) Sooseok (寒水石), which is mainly used to relieve skin, sensitized stone, which is effective for chronic skin ulcers and itching, and elvan, which is effective for eczema and dermatitis, and helps new tissue to new tissues. Talc is widely used as a skin protection agent because it has the effect of anti-corruption and ulcer treatment while removing moisture from skin and skin, and has the effect of anti-inflammatory and antipyretic effect, and skin lubrication and drying effect. As an active ingredient and herbal medicine, white paper and antipyretic, antipyretic, analgesic, and antipyretic, anti-inflammatory, antipyretic, anti-inflammatory, anti-inflammatory, anti-inflammatory, anti-inflammatory,Yellow ginseng with the equal efficacy and warm properties, the active ingredient of wild ginseng, which is effective in quenching thirst of the mouth, promoting the original function of the skin and anti-inflammatory effect of the mucous membrane, and having excellent skin care effect and a slight bactericidal power It can be achieved by an external preparation for treating skin diseases, which comprises a lake oil as a composition.

또한, 게르마늄, 한수석, 노감석, 맥반석, 밀타승, 활석과 같은 약리효과가 있는 천연광물을 지름 3㎝크기로 쪼개는 단계와;In addition, the step of dividing the pharmacological natural minerals, such as germanium, Hansu stone, sensitized stone, ganban stone, wheat batter, talc in 3cm diameter;

상기의 약리효과가 있는 천연광물을 72시간동안 300℃와 7000℃사이에서 가열하여 광물속의 수분을 증발시키고 유해성분을 녹여 제거하는 단계와; Heating the pharmacological natural minerals between 300 ° C. and 7000 ° C. for 72 hours to evaporate moisture in the mineral and to dissolve and remove harmful components;

백지, 황금, 황련, 산삼, 시호와 같은 약재 10g에 1000㏄의 물을 넣고 48시간 이상을 물의 부피가 20㏄가 되어 점성을 가질 때까지 끓이는 단계와; Adding 1000 물 of water to 10 g of medicinal herbs such as white paper, golden, rhubarb, wild ginseng, and shiho, and boiling for at least 48 hours until the volume of water reaches 20 ㏄ and has viscosity;

상기의 가열한 천연광물을 점성을 가지도록 끓인 한약재 달인 물에 담그는 단계와; Dipping the heated natural minerals in boiled herbal medicine water to have viscosity;

상기의 천연광물에서 증발된 수분과 녹은 유해성분의 공간으로 약재달인 물이 흡수되는 단계와; Absorbing medicinal water into the space of moisture and dissolved harmful components evaporated from the natural mineral;

상기의 약재성분이 흡수된 천연광물을 700메시(mesh)로 분쇄하여 분말형태로 만드는 단계와; Pulverizing the natural mineral absorbed by the above medicinal ingredients into 700 mesh to form a powder;

상기의 분쇄되어 생성된 분말에 호도유를 첨가하여 외용 연고형태로 만드는 피부질환 치료용 외용제의 제조방법에 의해서 달성된다. It is achieved by a method for producing an external preparation for treating skin diseases, in which an odor oil is added to the pulverized powder to form an external ointment.

상술한 바와 같이, 본 발명을 통해서 한의학적으로 증명된 약리효과를 이용하여 호르몬 제재 및 화학적 약물에서 나타나는 부작용을 최소화하고 아토피와 같은 피부질환의 치료 뿐만 아니라 신체적인 항산화능력과 피부재생능력을 극대화 할 수 있다.As described above, the present invention can minimize the side effects of hormone preparations and chemical drugs by using the pharmacologically proven medicinal effects and maximize the physical antioxidant capacity and skin regeneration ability as well as the treatment of skin diseases such as atopy. have.

상기에서 상술한 과제해결수단을 첨부된 도면을 참조하여 본 발명의 바람직한 실시예를 구체적으로 설명한다.Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

도 1은 본 발명인 피부질환 치료용 외용제를 제조하는 방법을 도시한 순서도이다. 본 발명에 따른 피부질환 치료용 외용제의 제조방법에 있어서 그 첫번째 단계는 천연광물을 가열하기 전에 지름 3㎝의 크기로 분쇄하여 다루기 쉬운 상태로 만든다. 큰 암석의 형태의 천연광물을 상기의 크기로 분쇄하여 다음 단계인 가열단계로 넘어가야 가열을 통해 얻은 수 있는 효과를 충분히 이룰 수 있다. 본 발명에서 대표적으로 이용되는 천연광물에는 한의학적으로 약리효과가 입증된 게르마늄, 한수석(寒水石), 노감석(爐甘石), 맥반석(麥飯石), 밀타승(密陀僧), 활석(滑石)이 대표적이다. 좀더 자세하게는 게르마늄은 항산화 작용, 면역 세포 수의 증가 효과, 콜레스테롤치 저하, 인터페론이 분비 유도 작용, 혈압강하와 혈약순환 개선 작용, 피부염에 분비물을 제거시키면서 방부, 수렴, 보호작용의 약리효과를 나타내고 노 감석(爐甘石)의 경우는 피부습진, 만성피부궤양, 가려움증에 효과를 나타내고 맥반석(麥飯石)은 피부종기와 악창에 배농 작용과 새 조직의 신생력을 도와주고 통증을 완화시키는 효과를 나타낸다. 밀타승(密陀僧)의 경우는 부패방지와 궤양치료에 좋으며 피부개선, 액취 항균 작용이 뛰어나고 소염, 해열작용에 효과가 있다. 그리고 활석(滑石)의 경우는 피부습진과 소아 피부염에 쓰이고 피부 윤활 작용과 건조 효과가 있고 피부보호제로 많이 응용되고 있다.1 is a flow chart illustrating a method for producing an external preparation for treating skin diseases of the present invention. In the manufacturing method of the external preparation for treating skin diseases according to the present invention, the first step is pulverized to a size of 3 cm in diameter before heating the natural mineral to make it easy to handle. Natural minerals in the form of large rocks should be crushed to the above size and then transferred to the next heating step to achieve the effect obtained by heating. Representative natural minerals used in the present invention include germanium, hansu (, 水 石), nogamite (맥 石), ganban stone (밀 石), miltaseung (활 石), talc (입증 石) has proven pharmacological effect in oriental medicine This is representative. More specifically, germanium has anti-oxidative effect, increase in immune cell number, lower cholesterol level, interferon secretion effect, lower blood pressure and blood circulation, remove secretions from dermatitis, and have pharmacological effects of antiseptic, astringent and protective effects. In the case of no-seokseok, it has effects on skin eczema, chronic skin ulcer, and itching. Macvanseok helps to drain the skin and swelling, help to regenerate new tissue, and to relieve pain. Indicates. Miltaseung is a good anti-corruption and ulcer treatment, skin improvement, odor antibacterial, anti-inflammatory, antipyretic effect is effective. And talc (滑石) is used for skin eczema and pediatric dermatitis, has a skin lubricating and drying effect, and is widely applied as a skin protection agent.

제 2단계에서는 가열하기에 알맞은 크기로 분쇄한 후 천연광물은 가열을 시작한다. 천연광물을 가열하여 내부에 포함되어 있는 수분을 증발시키고 또한 중금속과 같은 인체에 유해한 성분이 녹아내리고 순수한 천연광물의 성분만 남도록 가열한다. 처음에 300℃에서 가열을 시작하여 7000℃사이에서 적정온도로 가열을 한다. 72시간의 가열로 천연광물은 수분과 불순물이 제거된 상태가 되고 순수한 천연광물의 물질만이 남아 분쇄하기 쉬운 상태가 된다.In the second step, the natural mineral is comminuted to a size suitable for heating, and then the natural mineral starts heating. The natural minerals are heated to evaporate the moisture contained therein, and also heated to melt components harmful to the human body, such as heavy metals, and to leave only pure natural minerals. Initially, heating starts at 300 ℃ and heats to proper temperature between 7000 ℃. After 72 hours of heating, natural minerals are removed from moisture and impurities, and only pure natural minerals remain and are easily crushed.

제 3단계에서는 천연광물과 함께 혼합될 천연 한약재를 이용한다. 상기의 한약재의 약리성분을 추출하여 이용한다. 본 발명에서 이용하는 한약재는 백지, 황금, 황련, 산삼, 시호로 구성되어 있다. 좀더 자세하게는 백지(白芷)는 진통약으로 널리 이용되며 피부궤양에도 효과를 보이는 것으로 알려져 있다. 황금(黃芩)의 경우는 한방에서 뿌리를 해열, 이뇨, 지사, 이담 및 소염제로 이용한다. 황련(黃連)은 건위,진정,소염,항균등의 효능이 있는 것으로 알려져 있다. 시호(柴胡)라는 약재는 해열, 진통, 강장에 효과를 가진 약재이다. 산삼(山蔘)의 경우는 성질이 따뜻하고 입의 갈증해소와 피부의 본래 기능촉진과 점막의 소염작용에 효과가 있다. 상 기의 한약재를 10g당 1000㏄의 물로 100℃~150℃로 약48시간동안 끓인다. 약48시간동안 끓여서 물의 양이 20㏄정도되면 한약재에서 나온 진액과 약리성분으로 점성을 가진 액체상태가 된다.In the third step, a natural herbal medicine to be mixed with natural minerals is used. Extract and use the pharmacological components of the herbal medicine. Herbal medicine used in the present invention is composed of white paper, gold, yellow lotus, wild ginseng, shiho. More specifically, white paper (白芷) is widely used as an analgesic drug and is known to have an effect on skin ulcers. In the case of gold (黄 芩), the root is used as antipyretic, diuretic, branch, edema and anti-inflammatory drugs. Huangyan (黄連) is known to have the effect of dry stomach, soothing, anti-inflammatory, antibacterial. Shiho (柴胡) is a medicine that has an effect on fever, pain, and tonic. Sansam (山 蔘) is warm in nature and is effective in quenching thirst in the mouth, promoting the original function of the skin and anti-inflammatory action of the mucous membrane. Boil the herbal medicine at 100 ℃ ~ 150 ℃ for about 48 hours with 1000㏄ of water per 10g. When boiled for about 48 hours and the amount of water is about 20㏄, it becomes a viscous liquid with medicinal medicinal ingredients and medicinal ingredients.

제 4단계에서는 상기의 제 2단계에서 수분과 유해 불순물이 제거된 천연광물과 상기의 제 3단계에서 한약재에서 추출한 약리성분이 있는 점성이 있는 액체를 혼합하고 제 5단계에서 시간을 두고 천연광물에 액체성분이 흡수되도록 한다. In the fourth step, the natural mineral from which water and harmful impurities are removed in the second step and the viscous liquid containing the pharmacological component extracted from the herbal medicine in the third step are mixed with the natural mineral over time in the fifth step. Allow liquid components to be absorbed.

제 6단계에서는 충분한 시간을 두고 흡수되도록 하여 흡수가 충분히 된 천연광물을 입자의 크기단위로 700메쉬(mesh)의 크기로 분쇄하여 고운분말의 크기로 만든다. In the sixth step, the absorbed natural mineral is pulverized to a size of 700 mesh by the size of the particles to make the fine powder.

마지막 단계에서 상기의 작업으로 만들어진 분말에 우수한 피부관리 효과와 약간의 살균력을 가진것으로 알려진 호도유를 혼합하여 외용제형태의 모양을 갖춘다. In the final step, the powder produced by the above work is mixed with Lake Doho oil, which is known to have a good skin care effect and a slight bactericidal power, to form an external preparation.

<실시예 1>&Lt; Example 1 >

게르마늄 15g, 노감석 8g, 맥반석 13g, 밀타승 5g, 한수석 1g, 활석 13g의 천연광물을 850℃의 온도로 72시간 동안 가열하여 수분과 유해성분을 제거하고 백지, 황금, 시호, 황련, 산삼의 한약재를 10g과 1000㏄의 물을 첨가해 100℃로 48시간 동안 물의 양이 20㏄정도 될때까지 달였다. 엑기스를 추출하여 상기의 천연광물과 혼합하여 천연광물의 수분과 유해성분이 빠진자리로 충분히 흡수되도록 하고 700메시(mesh)의 크기로 분쇄하여 분말의 형태로 만든다. 상기의 작업 후 5.5g의 호도유를 첨가하고 균일하게 혼합하여 외용제 형태로 제조하였다.Natural minerals of germanium 15g, nogamite 8g, ganban stone 13g, millaseung 5g, hansuseok 1g, talc 13g are heated at a temperature of 850 ℃ for 72 hours to remove moisture and harmful components, and herbs of white paper, gold, shiho, rhubarb and wild ginseng 10 g of water and 1000 물 of water were added and decanted at 100 ° C. for 48 hours until the amount of water reached about 20 ㏄. The extract is extracted and mixed with the natural minerals so that the moisture and harmful components of the natural minerals are sufficiently absorbed into the missing spots and pulverized to a size of 700 mesh to form a powder. After the above operation, 5.5 g of odor oil was added and uniformly mixed to prepare an external preparation.

<실시예 2><Example 2>

게르마늄 30g, 노감석 15g, 맥반석 30g, 밀타승 10g, 한수석 2g, 활석 20g의 천연광물을 850℃의 온도로 72시간 동안 가열하여 수분과 유해성분을 제거하고 백지, 황금, 시호, 황련, 산삼의 한약재를 20g과 1000㏄의 물을 첨가해 150℃로 48시간동안 물의 양이 20㏄정도 될때까지 달인다. 엑기스를 추출하여 상기의 천연광물과 혼합하여 천연광물의 수분과 유해성분이 빠진자리로 충분히 흡수되도록하고 700메시(mesh)의 크기로 분쇄하여 분말의 형태로 만든다. 상기의 작업 후 5.5g의 호도유를 첨가하고 균일하게 혼합하여 외용제형태로 제조하였다. Natural minerals of germanium 30g, nogamite 15g, ganban stone 30g, millaseung 10g, hansuseok 2g, talc 20g are heated at a temperature of 850 ℃ for 72 hours to remove moisture and harmful components and herbal medicines of white paper, golden, shiho, rhubarb and wild ginseng 20g and 1000㏄ of water are added and heated to 150 ℃ for 48 hours until the amount of water reaches 20㏄. Extract the extract and mix it with the natural minerals so that the moisture and harmful components of the natural minerals are sufficiently absorbed into the missing spot, and crushed to a size of 700 mesh (mesh) to form a powder. After the above operation, 5.5 g of odor oil was added and uniformly mixed to prepare an external preparation.

도 2 ~ 도 4는 본 발명의 피부질환 치료용 외용제를 사용하여 아토피에 대한 치료 효과를 나타내는 도면으로서 약리활성의 효과를 나타낸다. 도 2는 본 발명의 외용제를 처방하기 전의 상태를 나타내는 도면이다. 도 3은 본 발명의 피부질환 치료제를 3개월 간 1일 2회의 빈도수로 1회에 2g~4g씩, 환부에 잘 스며들도록 고루 마사지한 후 치료 상태를 나타낸 사진이다. 도시된 바와 같이 상당부분 치료효과를 나타내는 것으로 보고되었다. 도 4는 본 발명의 피부질환 치료제를 5개월 간 1일 2회의 빈도수로 1회에 2g~4g씩 처방한 후 치료 상태를 나타낸 사진이다. 이를 통해 본 발명의 치료제를 5개월 간 처방하면 아토피가 거의 완치되는 것을 알 수 있다.2 to 4 is a view showing the therapeutic effect on atopy using the external preparation for the treatment of skin diseases of the present invention showing the effect of pharmacological activity. It is a figure which shows the state before prescribing the external preparation of this invention. Figure 3 is a photograph of the skin disease treatment agent after the massage evenly so as to permeate well to the affected area 2g ~ 4g at a frequency of twice a day for three months, three months. As shown, it has been reported to have a significant therapeutic effect. Figure 4 is a photograph showing the treatment state after the prescription for the skin disease treatment agent of the present invention 2g ~ 4g at a frequency twice a day for 5 months. It can be seen that the atopy is almost completely cured when prescribed for 5 months.

<시험예 1><Test Example 1>

상기의 실시예 1에 의해서 만들어진 외용제의 피부 도포시, 아토피 피부의 개선효과를 확인하기 위하여 다음과 같이 임상실험을 실시하였다. 5~30세의 아토피 환자로서, 2년 이상 아토피성 피부염을 앓고 있는 환자 50명에 대하여 아토피성 피부염 개선효과를 조사하였다. 상기의 실시예에 의해서 만들어진 외용제 타입의 치료제를 1일 2회이상, 1회에 2g~4g을 덜어서 환부에 잘 스며들도록 고루 마사지하도록 하였다. 상기의 방법으로 약 5일~ 90일간을 꾸준히 바르도록 하였다. 그 결과는 다음의 표에 나타내었다.When applying the skin of the external preparation made by the above Example 1, the clinical experiment was carried out as follows to confirm the improvement effect of atopic skin. The effect of improving atopic dermatitis was investigated in 50 patients with atopic dermatitis aged 5 to 30 years who had atopic dermatitis for more than two years. The external preparation type of the therapeutic agent made by the above example was twice or more a day, at a time of 2 g to 4 g less once to massage into the affected area well. By the above method was applied continuously for about 5 days to 90 days. The results are shown in the following table.

[표 1 실시예 1에 의해서 만들어진 외용제의 피부 도포 결과]TABLE 1 Skin application results of the external preparation made in Example 1




호전

Improvement

매우 호전

Very good

그저 그렇다.

so so.

5일째

Day 5

35%(17명)

35% (17 people)


65%(33명)

65% (33 people)

10일째

Day 10

70%(35명)

70% (35 people)

10%(5명)

10% (5 people)

20%(10명)

20% (10 people)

20일째

Day 20

65%(33명)

65% (33 people)

35%(17명)

35% (17 people)

30일째

Day 30

55%(28명)

55% (28 people)

45%(22명)

45% (22 people)

60일째

60 days

30%(15명)

30% (15 people)

70%(35명)

70% (35 people)

90일째

90 days

5%(3명)

5% (3 people)

95%(47명)

95% (47 people)

<시험예 2><Test Example 2>

상기의 실시예 2에 의해서 만들어진 외용제의 피부 도포시, 아토피 피부의 개선효과를 확인하기 위하여 다음과 같이 임상 실험을 실시하였다. 5~30세의 아토피 환자로서, 2년 이상 아토피성 피부염을 앓고 있는 환자 50명에 대하여 아토피성 피부염 개선효과를 조사하였다. 상기의 실시예에 의해서 만들어진 외용제 타입의 치료제를 1일 2회이상, 1회에 2g~4g을 덜어서 환부에 잘 스며들도록 고루 마사지하도록 하였다. 상기의 방법으로 약 5일~ 90일간을 꾸준히 바르도록 하였다. 그 결과는 다음의 표에 나타내었다.Clinical application was carried out as follows to confirm the improvement effect of atopic skin upon application of the external preparation made by Example 2 above. The effect of improving atopic dermatitis was investigated in 50 patients with atopic dermatitis aged 5 to 30 years who had atopic dermatitis for more than two years. The external preparation type of the therapeutic agent made by the above example was twice or more a day, at a time of 2 g to 4 g less once to massage into the affected area well. By the above method was applied continuously for about 5 days to 90 days. The results are shown in the following table.

[표 2 실시예 2에 의해서 만들어진 외용제의 피부 도포 결과]TABLE 2 Skin application results of the external preparation made in Example 2




호전

Improvement

매우호전

Very good

그저 그렇다.

so so.

5일째

Day 5

40%(20명)

40% (20 people)


60%(30명)

60% (30 people)

10일째

Day 10

60%(30명)

60% (30 people)

15%(7명)

15% (7 people)

25%(13명)

25% (13 people)

20일째

Day 20

65%(33명)

65% (33 people)

35%(17명)

35% (17 people)

30일째

Day 30

50%(25명)

50% (25 people)

50%(25명)

50% (25 people)

60일째

60 days

30%(15명)

30% (15 people)

70%(35명)

70% (35 people)

90일째

90 days

4%(2명)

4% (2 people)

96%(48명)

96% (48 people)

상기 표1 및 표2에서 나타난 바와 같이, 게르마늄, 노감석, 맥반석, 밀타승, 한수석, 활석의 천연광물과 백지, 황련, 황금, 시호, 산삼의 한약재에서 추출물을 혼합하여 제조한 실시예 2의 외용제는 우수한 아토피성 피부 개선 효과가 있다는 것을 알 수 있다.As shown in Table 1 and Table 2, the external preparation of Example 2 prepared by mixing the extract from the natural minerals of germanium, nogamite, ganban stone, Miltaseung, Hansuseok, talc and herbal medicines of white paper, rhubarb, gold, shiho, wild ginseng It can be seen that there is an excellent atopic skin improvement effect.

본 발명의 외용제를 환부에 도포하여 천연광물의 약리효과와 한약재의 약리효과를 동시에 작용시켜 호르몬 제재 및 화학적 약물에서 나타나는 부작용을 최소화하고 아토피와 같은 피부질환의 치료뿐만 아니라 신체적인 항산화능력과 피부재생능력을 극대화 할 수 있다.By applying the external preparation of the present invention to the affected part, the pharmacological effect of the natural mineral and the pharmacological effect of the herbal medicine are simultaneously acted to minimize the side effects of hormone preparations and chemical drugs, as well as the treatment of skin diseases such as atopy, as well as physical antioxidant capacity and skin regeneration. Maximize your skills.

도 1은 본 발명의 피부질환 치료용 외용제를 제조하는 방법을 도시한 순서도이다.1 is a flow chart illustrating a method for producing an external preparation for treating skin diseases of the present invention.

도 2는 도 2는 본 발명의 외용제를 처방하기 전의 상태를 나타내는 사진이다.Figure 2 is a photograph showing a state before prescribing the external preparation of the present invention.

도 3은 본 발명의 피부질환 치료제를 3개월 처방한 후의 치료 상태를 나타낸 사진이다. Figure 3 is a photograph showing the state of treatment after prescribing the skin disease treatment agent of the present invention for 3 months.

도 4는 본 발명의 피부질환 치료제를 5개월 처방한 후 치료 상태를 나타낸 사진이다.Figure 4 is a photograph showing the treatment state after prescribing the skin disease treatment agent of the present invention for 5 months.

<도면의 부호 설명><Description of the symbols in the drawing>

제 1단계 : 천연광물 분쇄First step: crushing natural minerals

제 2단계 : 천연광물 가열Second step: natural mineral heating

제 3단계 : 한약재 약성 추출Stage 3: Herbal Medicine Extraction

제 4단계 : 천연광물과 한약재추출액 혼합Fourth step: mixing natural minerals with herbal extracts

제 5단계 : 천연광물의 한약재추출액 흡수단계Step 5: Absorbing Herb Extracts of Natural Minerals

제 6단계 : 분말단계Step 6: Powder Step

Claims (2)

항산화작용과 피부염에 방부, 수렴, 보호작용을 하는 게르마늄과; Germanium antiseptic, astringent, and protective against antioxidant and dermatitis; 신열(身熱)의 번만(煩滿)과 피중여화(皮中如化)에 효과가 있는 한수석(寒水石)과;Hansuseok, which is effective in the burn-in of the heat and the feminization of blood; 피부 습진과 만성 피부궤양과 가려움증에 효과가 있는 노감석(爐甘石)과;Nogamseok, which is effective in skin eczema, chronic skin ulcer and itching; 습진과 피부염에 효과가 있는 맥반석(麥飯石)과;Elvan stones effective for eczema and dermatitis; 피부의 습기를 제거시키면서 부패방지와 궤양치료에 효과를 가지고 소염과 해열작용의 효과를 가진 밀타승(密陀僧)과;Miltaseung (密 陀 僧) having the effect of anti-corrosion and antipyretic effect while removing the moisture of the skin and has an effect on anti-corruption and ulcer treatment; 피부 윤활 작용과 건조 효과가 있어서 피부 보호제로 많이 응용되는 활석(滑石)으로 구성된 천연광물 혼합물과;A natural mineral mixture composed of talc having a skin lubricating action and a drying effect, and widely applied as a skin protection agent; 진통효과와 피부궤양에 효과가 있는 백지(白芷)와; White paper (白芷) and analgesic effect and skin ulcer effect; 해열, 진통에 효과를 가지는 시호(柴胡)와; Shiho (柴胡), which has an effect on antipyretic and analgesic; 해열과 소염제로서 효과를 가지는 황금(黃芩)과; Golden (黄 芩) has an effect as an antipyretic and anti-inflammatory agent; 건위, 진정, 소염, 항균등의 효능이 있는 황련(黃連)과; Huang Yan (黄連) with the efficacy of health, soothing, anti-inflammatory, antibacterial, etc .; 산삼(山蔘)으로 구성된 한약재 혼합물과; A herbal mixture consisting of wild ginseng; 상기 천연광물 혼합물과 한약재 혼합물에 호도유가 첨가된 것을 특징으로 하는 피부질환 치료제.Skin disease treatment agent, characterized in that the lake oil is added to the natural mineral mixture and the herbal mixture. 게르마늄, 한수석, 노감석, 맥반석, 밀타승, 활석을 지름 3㎝의 크기로 쪼개어 혼합하는 단계와;Dividing and mixing germanium, hansu, sensitized stone, elvan, mitta, talc into 3 cm in diameter; 상기 혼합물을 72시간 동안 300℃와 7000℃사이에서 가열하여 광물 속의 수분을 증발시키고 유해성분을 녹여 제거하는 단계와;Heating the mixture between 300 ° C. and 7000 ° C. for 72 hours to evaporate moisture in the mineral and to dissolve and remove harmful components; 백지, 황금, 황련, 산삼, 시호로 구성된 한약재 10g을 1000㏄의 물에 넣어 48시간 이상을 물의 부피가 20㏄가 되어 점성을 가질 때까지 끓이는 단계와;Adding 10 g of Chinese herbal medicine consisting of white paper, golden, rhubarb, wild ginseng, and siho into 1000 kPa of water and boiling for at least 48 hours until the volume of water reaches 20 kPa and has viscosity; 상기의 가열한 천연광물을 점성을 가지도록 끓인 한약재 달인 물에 담그는 단계와;Dipping the heated natural minerals in boiled herbal medicine water to have viscosity; 상기의 천연광물에서 증발된 수분과 녹은 유해성분의 공간으로 약재달인 물이 흡수되는 단계와;Absorbing medicinal water into the space of moisture and dissolved harmful components evaporated from the natural mineral; 상기의 약재성분이 흡수된 천연광물을 700메시(mesh)로 분쇄하여 분말형태로 만드는 단계와;Pulverizing the natural mineral absorbed by the above medicinal ingredients into 700 mesh to form a powder; 상기의 분쇄되어 생성된 분말에 호도유를 첨가하여 외용 연고형태로 만드는 피부질환 치료제의 제조방법.Method of producing a skin disease treatment agent by adding a pho oil to the powder produced by the pulverization to form an external ointment.
KR1020080138443A 2008-12-31 2008-12-31 The new medicine for skin disease composed of mineral and medical herbs KR20100079858A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020080138443A KR20100079858A (en) 2008-12-31 2008-12-31 The new medicine for skin disease composed of mineral and medical herbs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020080138443A KR20100079858A (en) 2008-12-31 2008-12-31 The new medicine for skin disease composed of mineral and medical herbs

Publications (1)

Publication Number Publication Date
KR20100079858A true KR20100079858A (en) 2010-07-08

Family

ID=42640899

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020080138443A KR20100079858A (en) 2008-12-31 2008-12-31 The new medicine for skin disease composed of mineral and medical herbs

Country Status (1)

Country Link
KR (1) KR20100079858A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102657780A (en) * 2012-05-31 2012-09-12 王孟理 Freckle-dispelling Chinese medicinal beautifying cream and preparation method thereof
CN102688318A (en) * 2012-04-19 2012-09-26 田杰 Traditional Chinese medicine composition for treating segmental vitiligo
CN104436043A (en) * 2014-11-26 2015-03-25 姜晓明 Analgesic anti-inflammatory ointment for treating sore and ulcer yang syndrome and preparation method thereof
CN104491189A (en) * 2014-12-24 2015-04-08 南阳理工学院 Traditional Chinese medicine powder for treating beriberi and controlling foot fatigue and preparation method of traditional Chinese medicine powder
CN104971002A (en) * 2015-06-19 2015-10-14 上海贝泰妮生物科技有限公司 Traditional Chinese medicinal composition preparation with anticorrosion efficacy, and preparation method thereof
CN105168502A (en) * 2015-10-10 2015-12-23 青岛云天生物技术有限公司 Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic
KR20190118429A (en) * 2018-04-10 2019-10-18 주식회사 케이티앤지 Composition for alleviating Atopic dermatitis and the manufacturing method of the same

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102688318A (en) * 2012-04-19 2012-09-26 田杰 Traditional Chinese medicine composition for treating segmental vitiligo
CN102657780A (en) * 2012-05-31 2012-09-12 王孟理 Freckle-dispelling Chinese medicinal beautifying cream and preparation method thereof
CN104436043A (en) * 2014-11-26 2015-03-25 姜晓明 Analgesic anti-inflammatory ointment for treating sore and ulcer yang syndrome and preparation method thereof
CN104491189A (en) * 2014-12-24 2015-04-08 南阳理工学院 Traditional Chinese medicine powder for treating beriberi and controlling foot fatigue and preparation method of traditional Chinese medicine powder
CN104971002A (en) * 2015-06-19 2015-10-14 上海贝泰妮生物科技有限公司 Traditional Chinese medicinal composition preparation with anticorrosion efficacy, and preparation method thereof
CN104971002B (en) * 2015-06-19 2018-03-13 昆明贝泰妮生物科技有限公司 A kind of Chinese medicinal composition preparation with preservative efficacy and preparation method thereof
CN105168502A (en) * 2015-10-10 2015-12-23 青岛云天生物技术有限公司 Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic
KR20190118429A (en) * 2018-04-10 2019-10-18 주식회사 케이티앤지 Composition for alleviating Atopic dermatitis and the manufacturing method of the same

Similar Documents

Publication Publication Date Title
CN100551422C (en) A kind of endo-medicine for the treatment of intervertebral disk hernia
KR20100079858A (en) The new medicine for skin disease composed of mineral and medical herbs
CN103417947A (en) Traditional Chinese medicine extract with effect of warmly invigorating kidney yang, method for manufacturing traditional Chinese medicine extract and kidney and umbilical warming ointment
CN104147533A (en) Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof
CN104001034A (en) Chinese herbal medicine ointment for treating burns and scalds
CN104689066A (en) Traditional Chinese medicine composition for treating burns and preparation method thereof
CN105687409A (en) Stone needle mud moxibustion and method for preparing same
CN107007724B (en) A Chinese medicinal liquid for health protection, and its preparation method
CN104352616A (en) Traditional Chinese medicine composition for treating sciatica and preparation method thereof
CN102327586A (en) Medicament for treating chilblain and preparation method thereof
CN102813900A (en) External medicine for treating foot corns
CN105079420A (en) Anesthesia ointment for wound surface and preparation method of anesthesia ointment
CN104784346A (en) Pruritus treating traditional Chinese medicine lotion preparation method
CN108498617A (en) Rheumatalgia Chinese medicine composition and its preparation method and application, lavipeditum packet and preparation method thereof and pharmaceutical preparation
CN105125708B (en) A kind of pharmaceutical composition and preparation method thereof for rhinitis
CN104147198A (en) Traditional Chinese medicine compound for treating papular acne and preparation thereof
CN103520289B (en) A kind of Chinese medicine composition for the treatment of constipation and its preparation method and application
CN102949544B (en) Chinese medicinal composition for specifically treating swelling of hands and feet of hemiplegic patients
CN102188550A (en) Topical preparation for treating tendon and bone injuries
CN110585379A (en) External application medicine for treating dermatitis
CN104189489A (en) Medicament with effect of treating chronic eczema and preparation method thereof
CN104352995A (en) Medicine for treating gall-stone and preparation method thereof
CN103223151A (en) Traditional Chinese medicinal composition for brightening and spot-removing and preparation method of preparation
CN105106590A (en) Medicine for treating allergic rhinitis
CN101940652A (en) Chinese medicinal liniment for treating psoriasis, multiple kinds of stubborn dermatitis and pruritus

Legal Events

Date Code Title Description
A201 Request for examination
A302 Request for accelerated examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
NORF Unpaid initial registration fee