CN116115721B - A topical Chinese medicinal unguent, and its preparation method and application - Google Patents

A topical Chinese medicinal unguent, and its preparation method and application Download PDF

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CN116115721B
CN116115721B CN202211732329.8A CN202211732329A CN116115721B CN 116115721 B CN116115721 B CN 116115721B CN 202211732329 A CN202211732329 A CN 202211732329A CN 116115721 B CN116115721 B CN 116115721B
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ointment
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turmeric
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郑虹
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Wuhan Benhoutang Traditional Chinese Medicine Clinic Co ltd
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Abstract

The invention relates to a traditional Chinese medicine composition ointment, which comprises 25-35 parts of herba violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae and 5-8 parts of endothelium corneum gigeriae galli, and the composition also comprises auxiliary materials, wherein the obtained traditional Chinese medicine composition ointment can effectively achieve better curative effects on symptoms such as acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle, hemorrhoids and the like.

Description

A topical Chinese medicinal unguent, and its preparation method and application
Technical Field
The present disclosure relates to the field of traditional Chinese medicine, and in particular, to an externally applied traditional Chinese medicine composition ointment.
Background
The traditional Chinese medicine is accumulation and summary of long-term medical practice experience of Chinese nationality, is a medical system with independent theoretical style and practical clinical curative effect, and is stand in the forests of world medicine and still keeps vigorous vitality until now. The theory of traditional Chinese medicine takes ancient culture with long history of China as background, and a series of original medical findings and medical inventions are gradually formed.
The traditional Chinese medicine is widely applied to modern medical treatment at present, and has good treatment effect, and has irreplaceable positions in the treatment modes of oral administration and external application. The external ointment of the traditional Chinese medicine is a semi-solid or near-solid preparation prepared by extracting traditional Chinese medicine raw materials and preparing active ingredients and matrixes, and can rapidly pass through skin and/or mucous membrane to achieve the local or systemic treatment effect. Compared with the oral decoction, the external ointment can avoid the first pass effect of the liver caused by the decoction of the traditional Chinese medicine and the irritation to the gastrointestinal tract, and the effective components of the medicine can reach the focus more directly, thereby rapidly achieving the treatment effect.
For skin and rheumatic disease symptoms such as acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis and tinea manuum, psoriasis, eczema, carbuncle and hemorrhoids and the like, the modern medical treatment is mainly caused by factors such as inflammation, infection and immune system disorder, and the modern medical treatment is mainly focused on inflammation diminishing, sterilization, immunity regulating and other aspects. In the field of traditional Chinese medicines, the symptoms are mainly caused by obstruction of qi and blood as toxin evil, internal generation of damp-heat, rising of yang heat, wind-cold-dampness arthralgia and the like, and the traditional Chinese medicine treatment is based on the principle that the comprehensive effects of clearing heat and detoxicating, dispelling wind and dredging collaterals, dispelling cold and eliminating dampness, activating blood and dissolving stasis are achieved to lighten or eliminate focus.
The combination formula of the traditional Chinese medicine directly determines the effect of the external traditional Chinese medicine ointment, and the publication number is as follows in the prior art, for example, the application is the university of Suzhou: CN112294867A, herba Salviae Plebeiae and radix Scutellariae compound acne cream, and its preparation method and application, by heating and mixing stearic acid, vaseline, lanolin, glyceryl monostearate and cetyl alcohol to obtain oil phase; melting and mixing glycerol and triethanolamine to obtain a water phase; mixing the water phase, the oil phase, the radix Scutellariae extract and the herba Salviae Plebeiae extract, adding water to desired volume, and mixing to obtain the compound acne cream. The novel external preparation cream is selected to prepare the traditional Chinese medicine cream, has strong adhesive force to skin and good biocompatibility, can effectively promote the medicine to permeate through skin cuticle to reach an action part to exert curative effect, not only improves the bioavailability of the medicine, reduces the medicine dosage and ensures the curative effect, but also can avoid the problem of irritation caused by overhigh local medicine concentration, is convenient and safe to use, and mainly depends on the antibacterial property of the common sage herb alcohol extract for treating skin lesions. The scheme uses traditional Chinese medicine components, but is more favorable for western medicine methods, mainly treats skin diseases based on substances with antibacterial action in traditional Chinese medicines, and is complex in preparation overall, high in technological requirements, and in addition, from the perspective of traditional Chinese medicines, the drug property of the plaster is difficult to estimate, and the drug effect and the treatment effect are not clear.
The application aims to provide a traditional Chinese medicine composition based on the defects that the preparation process of the traditional Chinese medicine external ointment in the prior art is complex, pharmacology is not clear, and more the ointment is possibly caused by the mechanism of the antibacterial action of a certain medicine, so that the traditional Chinese medicine composition has the advantages of mild efficacy and obvious treatment effect due to the mutual coordination and mutual adjustment of the traditional Chinese medicine components.
Disclosure of Invention
The present disclosure aims at providing an external ointment of a traditional Chinese medicine composition and a preparation method thereof, wherein the traditional Chinese medicine composition is mainly used for treating skin diseases caused by liver deficiency and blood dryness, loss of nourishment of the paws, damp-heat internal generation, rising of yang heat, wind-cold-dampness arthralgia and the like, and comprises acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle, hemorrhoids and the like.
Aiming at the pathogenesis of the skin diseases, the external ointment of the traditional Chinese medicine composition is mainly selected for treating the skin focus caused by invasion of wind cold into human bodies, damp-heat endogenous wind-cold-dampness arthralgia, qi and blood as toxin and congestion and heat toxin feeling, and the whole conception is to treat the disease symptoms caused by the pathogenesis by using a method of clearing heat and detoxicating, eliminating carbuncles and swelling and pain and activating blood circulation and removing obstruction in collaterals.
While the pathogenic heat invades the human body, or damp-heat is generated, qi and blood are blocked and not led through, which is classified into the dialectical theory of warm disease and the dialectical theory of defensive qi, nutrient and blood, the defensive principle is that the skin surface is the primary part of warm disease and the qi is the primary muscle; the nutrient governs the shallow and blood governs the deep.
From the common symptoms of skin patients such as acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle, hemorrhoids and the like, the analysis of symptoms is mostly that dysphoria with feverish sensation in the chest, warm pathogenic qi go deep into yin system, and blood heat goes recklessly, so that the symptoms mostly go deep into blood.
The traditional Chinese medicine composition has the advantages that one medicinal material with the functions of clearing heat and removing toxicity and eliminating carbuncles and swelling pain is more in selection range, and the commonly used viola philippica, dandelion, honeysuckle and the like have good heat and toxic materials clearing effects.
Herba Violae is mainly produced at the downstream of Yangtze river basin in China, and is prepared from dry whole herb, has cold nature and bitter taste, returns to heart and liver meridian, and has the effects of clearing heat and detoxicating, eliminating carbuncles and swelling pain, resolving hard mass and killing parasites. Zi Hua Di is better in clearing heat and removing toxicity and better in cooling blood.
In addition, the main chemical components in the viola yedoensis makino are flavonoids, coumarins and alkaloids, have certain antibacterial, antiviral and anti-inflammatory effects, and have better treatment effects on skin diseases caused by bacteria.
Clinically, there are many herbs for clearing heat and detoxicating, such as dandelion, flos Chrysanthemi Indici, honeysuckle and paris rhizome, but each herb has different effects of clearing heat and detoxicating.
For example, dandelion has the effects of clearing heat and removing toxicity, eliminating heat and resolving masses, inducing diuresis and treating stranguria, clearing liver and improving eyesight, but compared with viola yedoensis, the dandelion has the effects of more entering qi, dispelling depression and resolving masses, and has lower heat and toxic materials clearing and removing power than viola yedoensis; honeysuckle is sweet and cold, enters lung, heart and stomach meridians, has the effects of clearing heat and detoxicating and dispelling hot air, and has the antibacterial and anti-inflammatory effects which are inferior to those of viola yedoensis makino when being used as an external plaster.
Furthermore, one of the ideas of the scheme disclosed by the invention is to apply dialectical ideas of clearing heat and detoxicating, activating blood and removing obstruction in channels for treatment, and the viola philippica is selected as a monarch drug of a traditional Chinese medicine composition, and the viola philippica is in traditional Chinese medicine materials with the functions of clearing heat and detoxicating, has strong heat and detoxicating capability, has the effects of bacteriostasis, anti-inflammatory and the like, and can effectively play a role in treating pathogenesis.
Compared with other traditional Chinese medicines for clearing heat and detoxicating, the viola yedoensis has the advantages of being cold in nature, stronger in heat clearing and detoxicating effects, meanwhile, having the effects of killing parasites and resisting bacteria and resisting inflammation, and having a better symptomatic effect on symptoms caused by the fact that the pathogenic heat invades the human body, or damp-heat is generated internally, qi and blood are obstructed due to toxin evil, dysphoria with smothery sensation, the pathogenic heat enters yin and the blood heat is in delusion.
Furthermore, one of the conception of the present disclosure is that at least one Chinese medicine with the functions of clearing heat and detoxicating, promoting blood circulation and removing obstruction in channels is selected as an auxiliary medicine of the viola philippica, so that the efficacy is enhanced.
In the medicines for clearing heat and detoxicating, fructus forsythiae is bitter and cool in taste, enters heart, liver and gall meridians, has the effects of clearing heat, detoxicating, resolving hard mass and detumescence, and is used for treating carbuncle, scrofula, acute mastitis, erysipelas, early stage of warm diseases, warm camping, high fever polydipsia, unconsciousness and speckles, heat stranguria and pain, wind prevention and root taking medicine, has the functions of pungent taste, sweet taste and warm nature, has the effects of relieving exterior syndrome and sweating, dispelling wind and removing dampness, and is mainly used for treating wind-cold common cold, headache, fever, joint ache and tetanus.
For apparent symptoms caused by damp-heat toxin, the heat-clearing and detoxifying effects of the weeping forsythiae capsule and the divaricate saposhnikovia root are not as strong as those of the viola yedoensis, but the medicinal properties are not as good as those of the viola yedoensis, and the time and the medicinal effect of the two medicinal materials for invasion of damp-heat toxin into human bodies are different.
Furthermore, the concept of the present disclosure is based on the above factors, and the two traditional Chinese medicines of fructus forsythiae and radix sileris are selected as auxiliary medicines of the herba violae, and the fructus forsythiae and the radix sileris have the effects of clearing heat and detoxicating, but the differences of the medicine effect, the way of going and the action time are matched with and enhance the effects of clearing heat and detoxicating of the herba violae monarch medicine, so that the quick and efficient treatment effect is achieved.
Furthermore, one of the concepts of the present disclosure is to select at least one Chinese medicine for assisting the monarch and minister in clearing heat and detoxicating, promoting blood circulation and removing obstruction in collaterals, enhance the medicine effect, regulate the immunity and achieve the purpose of comprehensive treatment.
In the medicines for clearing heat and detoxicating, promoting blood circulation and removing obstruction in collaterals, turmeric is pungent, bitter and warm, enters liver and spleen channels, has the effects of breaking blood and promoting qi circulation, dispelling wind and relieving pain, and can be used for treating blood stasis and qi stagnation, traumatic injury, rheumatism, shoulder and arm pain. The turmeric is combined with the Viola yedoensis makino for use, and can be matched with the Viola yedoensis makino for clearing heat, detoxicating, cooling blood and detumescence, so as to dispel wind and promote blood circulation for patients until the disease is reached, wen Tonghan is clear.
Furthermore, the Chinese yew is bitter, pungent and slightly cold in nature, has the effects of resisting bacteria and inducing diuresis to reduce edema, and can be used for treating sore and carbuncle swelling.
In the prior analysis, the symptoms of acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle hemorrhoids and the like are caused by damp-heat, unsmooth menstrual flow and the like clinically at present, while the viola philippica has better curative effects on the symptoms in terms of clearing heat and detoxicating and treating menstrual flow and blood-component, but the viola philippica is inferior to other medicinal materials in terms of dispelling wind and promoting blood circulation and promoting urination and detumescence, and based on the etiology and pathogenesis of the symptoms, the therapeutic concept of the present disclosure is combined.
Furthermore, the concept of the present disclosure also lies in that turmeric and yew are selected as assistant and guide drugs, and the effects of breaking blood and promoting qi, dispelling wind and activating blood, dispelling wind and relieving pain of turmeric and the effects of resisting bacteria, promoting urination and reducing swelling of yew are utilized to improve the effects of the Viola yedoensis in treating the menstrual blood and clearing heat and detoxicating, and cooperatively treat symptoms caused by various damp-heat toxin, and simultaneously improve the effects of the two ministerial drugs of weeping forsythiae capsule and radix sileris.
Furthermore, one of the concepts of the present disclosure is to select at least one medicinal material that is used for guiding and harmonizing the properties of the medicinal materials.
Whereas dahurian angelica root nature taste: warm nature, pungent taste, fragrant smell and slight bitter taste, is often used for dispelling wind-damp, promoting blood circulation to remove pus, promoting granulation and relieving pain, and has the effect of keeping radix angelicae Dahurian also in beauty. Jinnei chicken is sweet in nature and calms, enters spleen, stomach, small intestine and bladder meridian. The two medicinal materials are opposite to the monarch drug Viola yedoensis makino; the ministerial drug fructus forsythiae and radix sileris; and the effects of turmeric and yew can play roles of harmonizing drug properties and guiding menstruation.
Furthermore, in order to enable the traditional Chinese medicine composition to be universally applied to clinic, the conception of the present disclosure also aims at providing a Chinese medicine composition in a paste form, wherein glycerin and pear juice are added into the composition, and the composition has the effects of harmonizing medicines and moistening nutrition skin.
Furthermore, aiming at clinical requirements in the prior art, the present disclosure provides an external ointment of a traditional Chinese medicine composition, wherein the ointment adopts herba violae as a monarch drug, and the herba violae is a main drug for leading the whole prescription to clear away heat and toxic materials and remove carbuncle swelling and pain.
In some embodiments, the external ointment of the traditional Chinese medicine composition further comprises two medicines of fructus forsythiae and radix sileris which are jointly used as ministerial medicines, wherein the two medicines of fructus forsythiae and radix sileris have the effects of strengthening wind dispelling, detoxifying, detumescence, resolving masses and relieving pain.
In some embodiments, the external ointment of the traditional Chinese medicine composition further comprises turmeric and yew, and the turmeric and the yew assist monarch and minister in activating blood, removing stasis, reducing swelling and pain and regulating immunity.
In some embodiments, the external ointment of the traditional Chinese medicine composition also comprises angelica dahurica, chicken's gizzard-membrane, angelica dahurica and chicken's gizzard-membrane, so that the traditional Chinese medicine properties of the traditional Chinese medicines can be blended, and the medicines can reach the swelling and pain location to warm pain, remove food retention, dissipate stagnation, dredge orifices, relieve pain and beautify skin.
In some embodiments, the external ointment of the traditional Chinese medicine composition further comprises glycerol, pear juice, and the glycerol and the pear juice are used as auxiliary materials, and has the effects of harmonizing medicines and moistening and nourishing skin.
In some embodiments, the present disclosure provides a Chinese medicinal composition paste comprising herba Violae, fructus forsythiae, radix Saposhnikoviae, rhizoma Curcumae Longae, taxus chinensis, radix Angelicae Dahuricae, and endothelium corneum Gigeriae Galli.
According to the pharmacology of the monarch, minister, assistant and guide of the traditional Chinese medicine, the viola yedoensis makino is a monarch drug, is a main drug for clearing heat and detoxicating, and is a main drug for main diseases; fructus forsythiae and radix sileris are used as ministerial drugs of auxiliary monarch drugs, have the effects of clearing heat and detoxicating, promoting blood circulation and removing obstruction in channels, have certain difference between the drug properties of menstruation and herba violae, and can play a role in improving the coordination; turmeric and yew are used as assistant and guide medicines for harmonizing medicine property and menstruation, and simultaneously regulating human immunity, promoting blood circulation, removing blood stasis and relieving swelling and pain; radix Angelicae Dahuricae and endothelium corneum Gigeriae Galli can make the medicine reach the part with swelling and pain, warm pain, resolving food stagnation, inducing resuscitation, relieving pain, and caring skin.
In the whole prescription provided by the scheme, aiming at skin diseases caused by liver deficiency and blood dryness, internal heat and damp, rising of yang heat, wind-cold-dampness arthralgia and the like, the whole thought is to fully consider the effects of all medicinal materials through clearing heat and detoxicating, promoting blood circulation and removing obstruction in collaterals and combining with the dialectical theory of defensive qi, ying and blood, and the medicinal materials are assembled through the dialectical theory of monarch, minister, assistant and guide, so that a better curative effect is achieved.
In some embodiments, the present disclosure also provides a Chinese medicinal composition paste comprising herba Violae, fructus forsythiae, radix Saposhnikoviae, rhizoma Curcumae Longae, taxus chinensis, radix Angelicae Dahuricae, endothelium corneum Gigeriae Galli, glycerol, and succus Pyri.
Compared with the scheme, the embodiment considers the situation of the traditional Chinese medicine preparation and the problems existing in the practical process, and glycerin and pear juice are added as auxiliary materials, so that the auxiliary materials are mainly used for moisturizing and nourishing skin, and the use experience of the traditional Chinese medicine composition paste is improved.
Further, in some embodiments, the present disclosure provides a Chinese medicinal composition paste, each of which is calculated by weight, the Chinese medicinal composition paste comprises 25-35 parts of herba Violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix Saposhnikoviae, 8-12 parts of Curcuma rhizome, 8-12 parts of Taxus chinensis, 5-8 parts of radix Angelicae Dahuricae, and 5-8 parts of endothelium corneum Gigeriae Galli.
Preferably, the Chinese medicinal composition paste is prepared from 30 parts of herba Violae, 15 parts of fructus forsythiae, 15 parts of radix sileris, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of radix angelicae and 6 parts of endothelium corneum gigeriae galli.
More preferably, the Chinese medicinal composition paste is prepared from 30 g of herba Violae, 15 g of fructus forsythiae, 15 g of radix sileris, 10 g of turmeric, 10 g of Chinese yew, 6 g of radix angelicae and 6 g of chicken's gizzard-skin.
In some embodiments, the present disclosure also provides a Chinese medicinal composition paste comprising 25-35 parts of Viola yedoensis, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae, 5-8 parts of chicken's gizzard-skin, 8-12 parts of glycerol and 4-8 parts of pear juice.
In some embodiments, the present disclosure also provides a Chinese medicinal composition paste comprising 25-35 parts of Viola yedoensis, 12-17 parts of fructus forsythiae, 12-17 parts of radix Saposhnikoviae, 8-12 parts of Curcuma rhizome, 8-12 parts of Taxus chinensis, 5-8 parts of radix Angelicae Dahuricae, 5-8 parts of endothelium corneum Gigeriae Galli, and 8-20 parts of Vaseline.
In some embodiments, the present disclosure also provides a method for preparing a Chinese medicinal composition paste, the method comprising weighing 25-35 parts of herba Violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix Saposhnikoviae, 8-12 parts of Curcuma rhizome, 8-12 parts of Taxus chinensis, 5-8 parts of radix Angelicae Dahuricae, and 5-8 parts of endothelium corneum Gigeriae Galli according to the above formula, extracting and decocting to obtain extract, and then compounding and combining the obtained extracts to obtain paste.
Further, in the traditional Chinese medicine composition ointment provided by the disclosure, the ointment is an extract of a traditional Chinese medicine material, and specifically comprises 25-35 parts of viola yedoensis extract, 12-17 parts of fructus forsythiae extract, 12-17 parts of radix sileris extract, 8-12 parts of turmeric extract, 8-12 parts of Chinese yew extract, 5-8 parts of radix angelicae extract and 5-8 parts of endothelium corneum gigeriae galli extract.
Furthermore, the Chinese medicinal composition paste also comprises auxiliary materials, wherein the auxiliary materials are one or more of glycerol, pear juice or vaseline;
or, further, the Chinese medicinal composition paste also comprises 8-12 parts of glycerol and 4-8 parts of pear juice.
Or, further, 8-20 parts of Vaseline is also included in the Chinese medicinal composition paste.
Further, in the traditional Chinese medicine composition ointment provided by the disclosure, the ointment is an extract of traditional Chinese medicine materials, and specifically comprises 30 parts of herba violae, 15 parts of fructus forsythiae, 15 parts of radix sileris, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of radix angelicae, 6 parts of endothelium corneum gigeriae galli, 10 parts of glycerol and 5 parts of pear juice.
Further, in the traditional Chinese medicine composition ointment provided by the disclosure, the ointment is an extract of traditional Chinese medicine materials, and specifically comprises 30 parts of herba violae, 15 parts of fructus forsythiae, 15 parts of radix sileris, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of radix angelicae, 6 parts of endothelium corneum gigeriae galli, 10 parts of glycerol and 10 parts of Vaseline.
Further, in the traditional Chinese medicine composition ointment provided by the disclosure, the ointment is an extract of traditional Chinese medicine materials, and specifically comprises 30 parts of herba violae, 15 parts of fructus forsythiae, 15 parts of radix sileris, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of radix angelicae, 6 parts of endothelium corneum gigeriae galli, 10 parts of glycerol and 10 parts of Vaseline.
Further, the present disclosure provides a Chinese medicinal composition paste, which is an extract of a Chinese medicinal material, and specifically comprises 30 parts of herba violae, 15 parts of fructus forsythiae, 15 parts of radix sileris, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of radix angelicae, 6 parts of endothelium corneum gigeriae galli and 10 parts of Vaseline.
In other embodiments, the present disclosure also provides a method for preparing a Chinese medicinal composition paste, the method comprising weighing Chinese medicinal materials according to the dosage of the formulation, weighing 25-35 parts of herba Violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix Saposhnikoviae, 8-12 parts of Curcuma rhizome, 8-12 parts of Taxus chinensis, 5-8 parts of radix Angelicae Dahuricae, and 5-8 parts of endothelium corneum Gigeriae Galli, mixing and cleaning the above medicinal materials, decocting with water, removing residues, and concentrating to obtain Chinese medicinal composition extract paste A.
Further, the preparation method of the traditional Chinese medicine composition paste further comprises the step of adding auxiliary materials into the traditional Chinese medicine composition extract paste A;
the auxiliary materials are one or more of glycerol, pear juice or vaseline;
or, further, the auxiliary materials in the Chinese medicinal composition paste are 8-12 parts of glycerol and 4-8 parts of pear juice.
Or, further, the auxiliary materials in the ointment of the traditional Chinese medicine composition are 8-20 parts of Vaseline.
In some embodiments, the present disclosure provides for the use of a Chinese medicinal composition paste, which is applied by topical application, which may be used against damp-heat caused lesions.
The focus of infection caused by damp heat comprises acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle, hemorrhoid, etc.
Compared with the prior art, the traditional Chinese medicine composition ointment aims at symptoms caused by damp and heat, a solution is found from traditional Chinese medicines, the whole concept is to treat diseases caused by the pathogenesis by using a method of clearing heat and detoxicating, eliminating carbuncles and swelling pain, promoting blood circulation and removing obstruction in collaterals, and the combination of the Chinese medicinal materials including the Chinese violet, fructus forsythiae, radix sileris, turmeric, taxus chinensis, radix angelicae, endothelium corneum gigeriae galli, glycerol and pear juice can effectively achieve a better curative effect on the symptoms including acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manus, psoriasis, eczema, carbuncle, hemorrhoids and the like by considering the dialectical theory of monarch, minister, assistant and guide, defensive qi, nutrient and blood.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present disclosure, and other drawings may be obtained according to these drawings for a person having ordinary skill in the art.
Fig. 1: the plaster of the traditional Chinese medicine composition prepared in the example 2 is stored for one month;
fig. 2: the plaster of the traditional Chinese medicine composition prepared in the example 1 is stored for one month;
fig. 3: photo of patient before tinea pedis treatment;
fig. 4: photographs of the patient after one week of treatment;
fig. 5: a photograph of a treatment for head acne.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides a traditional Chinese medicine composition paste, which is prepared from, by weight, 25-35 parts of herba violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae and 5-8 parts of endothelium corneum gigeriae galli.
Wherein the dosage of the viola philippica can be 20 parts, 35 parts, 30 parts and 35 parts; the range of the viola philippica can be 25-30 parts and 22-32 parts.
In some embodiments, the amount of fructus forsythiae may be 12 parts, 13 parts, 15 parts, 17 parts; fructus forsythiae may be 12-15 parts, 13-15 parts, 14-17 parts.
In some embodiments, the amount of the wind guard may be 12 parts, 13 parts, 15 parts, 17 parts; the range of the wind prevention can be 12-15 parts, 13-15 parts and 14-17 parts.
In some embodiments, the turmeric may be used in an amount of 8 parts, 9 parts, 10 parts, 11 parts, 12 parts; turmeric may range from 8-11 parts, 8-10 parts, 9-12 parts.
In some embodiments, the amount of the taxus chinensis is 8 parts, 9 parts, 10 parts, 11 parts, 12 parts; the Chinese yew can be 8-11 parts, 8-10 parts, and 9-12 parts.
In some embodiments, the amount of the angelica dahurica can be 5 parts, 6 parts, 7 parts, 8 parts; the dosage range of the angelica dahurica can be 5-7 parts and 6-8 parts.
In some embodiments, the amount of endothelium corneum Gigeriae Galli may be 5 parts, 6 parts, 7 parts, 8 parts; the dosage range of the chicken's gizzard-membrane can be 5-7 parts and 6-8 parts.
In some embodiments, the Chinese medicinal composition paste in the previous embodiments further comprises an auxiliary material, wherein the auxiliary material is one or more of glycerin, pear juice or vaseline.
Wherein the dosage of the glycerol can be 8 parts, 9 parts, 10 parts, 11 parts and 12 parts; the glycerol can be 8-11 parts, 8-10 parts, 9-12 parts;
the consumption of the pear juice can be 4 parts, 5 parts, 6 parts and 8 parts, and the range of the pear juice can be 4-6 parts and 5-8 parts;
the dosage of the glycerol can be 8 parts, 10 parts, 15 parts and 20 parts; the dosage range of the Vaseline can be 8-15 parts, 10-15 parts and 18-20 parts;
the invention discloses a method for preparing the ointment, which comprises the steps of extracting medicines individually, specifically weighing Chinese violet, fructus forsythiae, radix sileris, turmeric, yew, radix angelicae and chicken's gizzard-membrane, extracting and decocting the medicines individually to obtain extracts, and then compounding and combining the obtained extracts according to the proportion of the traditional Chinese medicines to prepare the ointment.
The invention discloses another method for preparing the paste, in another embodiment, the method comprises the steps of mixing traditional Chinese medicine raw materials according to the traditional Chinese medicine formula, leaching to obtain the paste, compounding the paste, and supporting the final paste.
Specific examples are as follows:
the preparation method adopted is that the Chinese medicine is extracted by single leaching, and then is compounded according to the formula disclosed by the invention to obtain the ointment.
The specific formulation is shown in the following table:
the ointment is prepared according to the specific formula, and is used for treating acne, gout, arthralgia, erythema nodosum, vasculitis, tinea pedis, tinea manuum, psoriasis, eczema, carbuncle, hemorrhoids and the like.
In the case of the pastes prepared in examples 1 and 2, the initial state of the paste is a brownish black viscous paste, but the paste prepared in example 1 is not easy to store, and can be mildewed after being stored for several weeks, while the paste prepared in example 2 is stored for several months without mildew.
In comparison with the effects of examples 3 and 4 and example 2, examples 3 to 4 also have the effects of clearing heat and detoxicating, and removing heat and resolving masses, but compared with the ointment of example 2, the treatment time in terms of eczema, acne and tinea pedis and tinea manus is obviously longer than that of the ointment of example 2, and the overall effect is not the ointment obtained in example 2, which is probably brought about by the more powerful heat clearing effect of the viola yedoensis and is more brought about by the overall scheme of the ointment.
In addition, when the pastes obtained in examples 5 to 9 were applied to practical processes, it was found that the effects of examples 5 to 9 were still inferior to those of example 1, and the treatment effect and treatment period were relatively inferior.
As can be seen from fig. 1 and 2, the storage time of the paste is greatly affected when different formulations of the auxiliary materials are used, in fig. 1, vaseline is used as the auxiliary material, and glycerin and pear juice are used as the auxiliary material, and the main purpose of the auxiliary material is to increase the fluidity of the paste, but obvious mildew phenomenon occurs after glycerin and pear juice are used as the auxiliary materials.
Figures 3 and 4 show the treatment of tinea pedis with the paste of example 2, with a significant improvement after one week of quality.
Fig. 5 shows that the therapeutic effect is remarkable in treating acne.
While certain exemplary embodiments of the present disclosure have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that modifications may be made to the described embodiments in a variety of different ways without departing from the spirit and scope of the present disclosure. Accordingly, the drawings and description are to be regarded as illustrative in nature and not as restrictive of the scope of the disclosure.

Claims (6)

1. A Chinese medicinal composition external ointment is characterized in that the Chinese medicinal composition ointment comprises 25-35 parts of herba violae, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae and 5-8 parts of endothelium corneum gigeriae galli.
2. A topical Chinese medicinal composition paste according to claim 1, wherein,
the Chinese medicinal composition ointment comprises 30 parts of Chinese violet, 15 parts of weeping forsythia, 15 parts of divaricate saposhnikovia root, 10 parts of turmeric, 10 parts of Chinese yew, 6 parts of dahurian angelica root and 6 parts of chicken's gizzard-membrane.
3. A topical Chinese medicinal composition paste according to claim 1, wherein,
the Chinese medicinal composition ointment comprises 30 g of Chinese violet, 15 g of weeping forsythia, 15 g of divaricate saposhnikovia root, 10 g of turmeric, 10 g of Chinese yew, 6 g of dahurian angelica root and 6 g of chicken's gizzard-membrane.
4. A topical Chinese medicinal composition paste according to any one of claims 1-2, wherein,
the auxiliary materials in the Chinese medicinal composition paste are 8-20 parts of Vaseline.
5. The external ointment of the traditional Chinese medicine composition according to claim 4, wherein the preparation method of the external ointment of the traditional Chinese medicine composition is characterized by weighing 25-35 parts of viola yedoensis, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae and 5-8 parts of chicken's gizzard-membrane, extracting and decocting the extracts singly, and then compounding and combining the extracts to prepare the ointment.
6. The external ointment of the traditional Chinese medicine composition according to claim 4, wherein the preparation method of the external ointment of the traditional Chinese medicine composition is characterized by weighing 25-35 parts of viola yedoensis, 12-17 parts of fructus forsythiae, 12-17 parts of radix sileris, 8-12 parts of turmeric, 8-12 parts of Chinese yew, 5-8 parts of radix angelicae and 5-8 parts of chicken's gizzard-membrane, mixing and cleaning, adding water, decocting, deslagging and concentrating to obtain an extract of the traditional Chinese medicine composition, and compounding and combining the obtained extracts to prepare the ointment.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN109731053A (en) * 2018-12-29 2019-05-10 广州市紫松贸易有限公司 A kind of Chinese medicine composition that treating dark sore or whelk, paste and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN109731053A (en) * 2018-12-29 2019-05-10 广州市紫松贸易有限公司 A kind of Chinese medicine composition that treating dark sore or whelk, paste and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
冯彬彬等.中药药理 供中药学、中药制药、中药材生产与加工专业用.中国医药科技出版社,2021,(第1版),177. *
汪毅.精选草药彩色图谱 1.贵州科技出版社,2014,(第1版),59. *
薄文斌等.石志超学术思想及临床经验集.中国中医药出版社,2022,(第1版),360. *
顾润环等.神农本草经研究与运用.中医古籍出版社,2021,(第1版),139. *

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