CN105362456A - Oral medicine for treating early stage cervical cancer and preparation method thereof - Google Patents

Oral medicine for treating early stage cervical cancer and preparation method thereof Download PDF

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Publication number
CN105362456A
CN105362456A CN201510841730.9A CN201510841730A CN105362456A CN 105362456 A CN105362456 A CN 105362456A CN 201510841730 A CN201510841730 A CN 201510841730A CN 105362456 A CN105362456 A CN 105362456A
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medicine
radix
treatment
cervical cancer
cervical carcinoma
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孙素蓉
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and aims to provide an oral medicine for treating early stage cervical cancer according to a know mechanism of the traditional Chinese medicine on the early stage cervical cancer. The medicine comprises the following various components in parts by mass: 10-17 g of radices trichosanthis, 5-15 g of spina gleditsiae, 15-25 g of honeysuckle flowers, 15-25 g of fructus forsythia, 10-30 g of dried radix rehmanniae, 5-15 g of Angelica sinensis, 2.5-15 g of radix glycyrrhizae, 1.5-3 g of coptidis rhizome and 1-2 g of Momordica cochinchinensis (processed). The medicine is good in effect, takes effect quickly, and is a traditional Chinese medicines formula capable of treating both symptoms and root causes.

Description

A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of endo-medicine for the treatment of early cervical carcinoma, particularly for the field of the endo-medicine and preparation method thereof of early cervical carcinoma patient.
Background technology
Cervical cancer is modal gynecologic malignant tumor.The cancer in situ age occurred frequently is 30 ~ 35 years old, and infiltrating carcinoma is 45 ~ 55 years old, and its morbidity in recent years has the trend of rejuvenation.The generally application of nearly cervical cytology examination decades, makes cervical cancer and precancerous lesion be able to early discovery and treatment, and the M & M of cervical cancer is existing obviously to decline.
So, with regard to how finding a kind of medicine effectively can treating above-mentioned early cervical carcinoma, be the problem that we should solve at present.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment early cervical carcinoma, people appreciate the advantage of the above-mentioned disease of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, for the present situation of the above-mentioned early cervical carcinoma of existing western medical treatment, the object of the invention is to be to provide a kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, to solve early cervical carcinoma patient restorative problem early.This medicine be with common Chinese medicine for raw material, there is instant effect, the feature such as evident in efficacy, and effectively can treat above-mentioned early cervical carcinoma one disease.
For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 10 ~ 17g, Spina Gleditsiae 5 ~ 15g, Flos Lonicerae 15 ~ 25g, Fructus Forsythiae 15 ~ 25g, the Radix Rehmanniae 10 ~ 30g, Radix Angelicae Sinensis 5 ~ 15g, Radix Glycyrrhizae 2.5 ~ 15g, Rhizoma Coptidis 1.5 ~ 3g, process Semen Momordicae 1 ~ 2g.
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 11 ~ 14.5g, Spina Gleditsiae 6 ~ 13g, Flos Lonicerae 15 ~ 21g, Fructus Forsythiae 15 ~ 21g, the Radix Rehmanniae 11 ~ 25g, Radix Angelicae Sinensis 6 ~ 13g, Radix Glycyrrhizae 3 ~ 13g, Rhizoma Coptidis 1.5 ~ 2.5g, process Semen Momordicae 1 ~ 1.5g.
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, is characterized in that, each component of the medicine of described " preferred plan " and mass parts thereof are than as follows:
Radix Trichosanthis 12g, Spina Gleditsiae 11g, Flos Lonicerae 18g, Fructus Forsythiae 18g, Radix Rehmanniae 18g, Radix Angelicae Sinensis 11g, Radix Glycyrrhizae 8g, Rhizoma Coptidis 2.5g, process Semen Momordicae 1g.
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, is characterized in that, described method comprises the steps to be prepared from:
A, first raw material Chinese medicine is picked decontamination and dust after, decoct a drug wrapped than being ground into coarse respectively according to mass parts;
B, the raw material Chinese medicine wrapped put into cold boiled water and soak 30 minutes, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 34mm carries out first time decoction 45 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 40 minutes, twice mixing be condensed into 50% herb liquid 400 milliliters for subsequent use.
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, is characterized in that, described instructions of taking is: taken with one day by the herb liquid prepared, every day potion, sooner or later sub-service, dosage 200 milliliters/time, taking medicine before meal.Take medicine 30-180 days, and symptom alleviates gradually.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine.The present invention selects wherein modal Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Radix Trichosanthis, nature and flavor: sweet, micro-hardship, to be slightly cold, have effect of clearing away heat-fire, promoting the production of body fluid to quench thirst, detumescence and apocenosis, be used for the treatment of calentura excessive thirst, lung-heat type cough, interior-heat are quenched one's thirst, sore swollen toxin;
Spina Gleditsiae, nature and flavor: there is the saturating pus of sterilization, search effect of wind, parasite killing, be used for the treatment of swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy;
Flos Lonicerae, nature and flavor: sweet in the mouth, cold in nature, have heat-clearing and toxic substances removing, dispelling wind and heat pathogens, dredge effect of throat, relieving restlessness of relieving summer heat, be used for the treatment of the diseases such as febrile disease due to summer-heat pathogen, dysentery, influenza, furuncle toxic swelling, acute and chronic tonsillitis, periodontitis;
Fructus Forsythiae, nature and flavor: bitter in the mouth, cold nature, there is effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, be used for the treatment of anemopyretic cold, epidemic febrile disease swells and ache from the beginning of, scorching larynx, macule, erysipelas, carbuncle knot toxic swelling, tuberculous lymphadenitis, hyperpyrexia excessive thirst, coma send out the diseases such as speckle, scrofula, urinary tract infection;
The Radix Rehmanniae, nature and flavor: sweet in the mouth, hardship, to be slightly cold, there is nourishing YIN and clearing away heat, effect that removing heat from blood is enriched blood, quench one's thirst for calentura excessive thirst, interior-heat, hectic fever due to YIN-deficiency consumptive fever, epidemic febrile disease send out haematemesis, metrorrhagia, hematuria caused by speckle, heat in blood, have blood in stool, blood deficiency and yellow complexion, dizzy cardiopalmus, insufficiency of blood amenorrhea etc.;
Radix Angelicae Sinensis, nature and flavor:, warm in nature, sweet in the mouth is pungent, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, be used for the treatment of blood deficiency, shallow complexion, dizzy cardiopalmus, blood deficiency or have the pain cards such as the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, angina pectoris, rheumatic arthralgia, traumatic injury concurrently;
Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, be used for the treatment of lack of appetite, weakness of the spleen and stomach, stomachache loose stool, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity and strong;
Rhizoma Coptidis, nature and flavor: bitter, cold, have effect of heat clearing and damp drying, eliminating fire and detoxication, be used for the treatment of damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tell nosebleed, conjunctival congestion, have a toothache, quench one's thirst, carbuncle furuncle, external treatment eczema, eczema, auditory meatus is suppurated;
Process Semen Momordicae, nature and flavor: bitter micro-sweet, warm, poisonous, there is effect of dispersing swelling and dissipating binds, toxic removing, be used for the treatment of carbuncle, furuncle, scrofula, hemorrhoid, innominate toxic swelling, tinea skin ulcer, rheumatic arthralgia, the contracture of muscle arteries and veins.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment early cervical carcinoma and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to early cervical carcinoma one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Detailed description of the invention
The present invention is exactly treatment for above-mentioned early cervical carcinoma and a kind of Chinese medicine formula proposed, and the medicine effect adopting this formula to prepare is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Be described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 12g, Spina Gleditsiae 11g, Flos Lonicerae 18g, Fructus Forsythiae 18g, Radix Rehmanniae 18g, Radix Angelicae Sinensis 11g, Radix Glycyrrhizae 8g, Rhizoma Coptidis 2.5g, process Semen Momordicae 1g.
Embodiment 2:
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 14.5g, Spina Gleditsiae 13g, Flos Lonicerae 21g, Fructus Forsythiae 21g, Radix Rehmanniae 25g, Radix Angelicae Sinensis 13g, Radix Glycyrrhizae 13g, Rhizoma Coptidis 2.5g, process Semen Momordicae 1.5g.
Embodiment 3:
A kind of endo-medicine for the treatment of early cervical carcinoma and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 17g, Spina Gleditsiae 15g, Flos Lonicerae 25g, Fructus Forsythiae 25g, Radix Rehmanniae 30g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae 15g, Rhizoma Coptidis 3g, process Semen Momordicae 2g.
Model case:
Through clinical conditions early cervical carcinoma patient totally 200 examples, the age is more than 35 years old 118 routine, only has 82 examples to be less than 35 years old.29 examples of fully recovering in 200 routine patients, effective 135 examples, invalid 36 examples, total effective rate reaches 82%.After treatment, symptom obviously alleviates, and patient has had new confidence to life.

Claims (3)

1. treat an endo-medicine for early cervical carcinoma, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 10 ~ 17g, Spina Gleditsiae 5 ~ 15g, Flos Lonicerae 15 ~ 25g, Fructus Forsythiae 15 ~ 25g, the Radix Rehmanniae 10 ~ 30g, Radix Angelicae Sinensis 5 ~ 15g, Radix Glycyrrhizae 2.5 ~ 15g, Rhizoma Coptidis 1.5 ~ 3g, process Semen Momordicae 1 ~ 2g.
2. the endo-medicine for the treatment of early cervical carcinoma according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 11 ~ 14.5g, Spina Gleditsiae 6 ~ 13g, Flos Lonicerae 15 ~ 21g, Fructus Forsythiae 15 ~ 21g, the Radix Rehmanniae 11 ~ 25g, Radix Angelicae Sinensis 6 ~ 13g, Radix Glycyrrhizae 3 ~ 13g, Rhizoma Coptidis 1.5 ~ 2.5g, process Semen Momordicae 1 ~ 1.5g.
3. the endo-medicine for the treatment of early cervical carcinoma according to claim 1 and 2, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Trichosanthis 12g, Spina Gleditsiae 11g, Flos Lonicerae 18g, Fructus Forsythiae 18g, Radix Rehmanniae 18g, Radix Angelicae Sinensis 11g, Radix Glycyrrhizae 8g, Rhizoma Coptidis 2.5g, process Semen Momordicae 1g.
CN201510841730.9A 2015-11-28 2015-11-28 Oral medicine for treating early stage cervical cancer and preparation method thereof Withdrawn CN105362456A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853923A (en) * 2016-05-17 2016-08-17 王德玉 Pure traditional Chinese medicinal preparation for treating early-stage cervical carcinoma
CN107375553A (en) * 2017-08-10 2017-11-24 熊润之 A kind of whey tea prescription for preventing and treating HPV viruse infection and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784245A (en) * 2015-03-17 2015-07-22 刘长源 Medicine for treating cervical cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784245A (en) * 2015-03-17 2015-07-22 刘长源 Medicine for treating cervical cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
哈孝贤: "漫谈子宫颈白斑及中医的治疗", 《开卷有益.求医问药》 *
郭宏昌: "《中草药抗肿瘤便览》", 30 November 2014, 新疆人民卫生出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853923A (en) * 2016-05-17 2016-08-17 王德玉 Pure traditional Chinese medicinal preparation for treating early-stage cervical carcinoma
CN107375553A (en) * 2017-08-10 2017-11-24 熊润之 A kind of whey tea prescription for preventing and treating HPV viruse infection and preparation method thereof

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Application publication date: 20160302