CN104971331A - Orally-taken externally-applied traditional Chinese medicine composition for treating proliferation of mammary gland and preparation method - Google Patents
Orally-taken externally-applied traditional Chinese medicine composition for treating proliferation of mammary gland and preparation method Download PDFInfo
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Abstract
The invention relates to an orally-taken externally-applied traditional Chinese medicine composition for treating proliferation of mammary gland. The orally-taken externally-applied traditional Chinese medicine composition is characterized by comprising orally-taken pills and externally-applied paste; the orally-taken pills are prepared from the following Chinese herbal raw materials: Chinese thorowax root, rhizoma cyperi, olibanum, angelica sinensis, ligusticum wallichii, the root of red-rooted salvia, manis pentadactyla, curcuma zedoaria, raw oyster shell, poria cocos, herba leonuri, rhizoma sparganii, thunberg fritillary bulb, selfheal, codonopsis pilosula, the seed of cowherb, carthamus tinctorius, curcuma aromatica, asparagus cochinchinensis, dandelion, roasted ginger, fried atractylodes macrocephala koidz, cornu cervi degelatinatum, scutellaria baicalensis and schisandra chinensis; and the externally-applied paste is prepared from the following traditional Chinese medicine raw materials in parts by weight: myrrh, kelp, clematis chinensis, tree peony bark, mulberry twig, hive, gecko, eucommia ulmoides, lindera aggregata, pseudo-ginseng, impatiens balsamina, endothelium corneum gigeriae galli, eel blood, angelica dahurica, cassia twig, mylabris, borneol, sesame oil and yellow lead. According to the invention, by combining the orally-taken pills and the externally-applied paste, the proliferation of mammary gland can be treated, a treatment effect is obvious and low possibility in relapse is realized.
Description
Technical field
The present invention is applied to Chinese medicine formula and the manufacture method of cyclomastopathy with inside and outside combination, relates to technical field of Chinese medicines; In particular to Chinese medicine formula and manufacture method technical field; Particularly relate to and be applied to the Chinese medicine formula of cyclomastopathy and the purposes technical field of manufacture method with inside and outside combination; Be specifically related to the Chinese medicine formula and the manufacture method technical field that are applied to cyclomastopathy with inside and outside combination.
Background technology
Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of cystic hyperplasia of breast.This sick sickness rate is in ascendant trend year by year in recent years.According to investigations, have the women of 70 ~ 80% to have cyclomastopathy in various degree, as not treated as soon as possible, time one length will be converted into breast carcinoma, the life security of serious harm extensive patients.
The routine treatment of cyclomastopathy mainly comprises western medicine, operative treatment, hormone therapy and external medication.They are alleviating the symptom of cyclomastopathy, and suppress state of an illness aspect really to have certain effect, but all fundamentally can not root out the cause of disease, thus recurrence is commonplace, and bring all injuries seriously to patient body organ, side effect is large simultaneously.
Doctor trained in Western medicine is understood fully at present not yet completely to the understanding of the cause and onset of disease mechanism of cyclomastopathy; but its morbidity is mainly because the viewpoint of endocrine hormone imbalance is by Most scholars is generally acknowledged; therefore; theoretical according to the etiology of sexual hormone disturbance; the treatment of cyclomastopathy mainly regulates ovarian endocrine tend to normal or block hormonal action target spot, alleviates clinical symptoms.Clinical many employing endocrine therapy schemes and operative therapy, also have the auxiliary treatment such as vitamin, Operand, diuretic in addition.Cyclomastopathy belongs to endocrine system disease, and itself is without the indication of operative treatment, and operative treatment damage surface is large, cures the symptoms, not the disease, easily recurs again, therefore do not advise that cyclomastopathy patient applies.In a word, western medical treatment primary disease is many just to be alleviated or improves symptom, and side effect is large, more disorderly by it improper hormone in vivo balance that instead can make, and is difficult to the Histological change after making cyclomastopathy and is restored.
The traditional Chinese medical science thinks that disease occurrence cause is exopathogenic factor and endogenous cause of ill, and endogenous cause of ill exopathogenic factor interacts, and makes yin-Yang unbalance, and QI and blood is lost permanent and gives birth to disease.Liver and kidney two is the closest through the relation with breast, and stagnation of QI due to depression of the liver, feelings will internal injury have material impact in the pathogenic process of cyclomastopathy.The traditional Chinese medical science, according to the mechanism of depressed liver-energy dispersing and QI regulating, harmonizing the functional activities of vital QI, blood circulation promoting and blood stasis dispelling, dredging the meridian, resolving phlegm and softening hard masses, dispersing swelling and dissipating binds, reaches the object of disease therapy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition of oral administration and externally combined treatment cyclomastopathy, therapeutic effect is obvious, and have no side effect, cure rate is high, in conjunction with on the basis of Chinese medicine for oral administration, external application affected part, soothing the liver reason seven, resolving depression eliminating stagnation, synchronous therapeutic, evident in efficacy.
For achieving the above object, Chinese medicine of the present invention comprises pill for oral administration and Dressed plaster, wherein pill for oral administration is made up of the medium-height grass raw material of following weight portion: Radix Bupleuri 15-20 part, Rhizoma Cyperi 10-15 part, Olibanum 10-15 part, Radix Angelicae Sinensis 15-18 part, Rhizoma Chuanxiong 10-12 part, Radix Salviae Miltiorrhizae 15-20 part, Squama Manis 10-15 part, Rhizoma Curcumae 10-15 part, Concha Ostreae 15-30 part, Poria 10-25 part, Herba Leonuri 10-20 part, Rhizoma Sparganii 9-15 part, Bulbus Fritillariae Thunbergii 5-15 part, Spica Prunellae 6-18 part, Radix Codonopsis 10-15 part, king does not stay 5-15 part, Flos Carthami 5-15 part, Radix Curcumae 10-15 part, Radix Asparagi 10-15 part, Herba Taraxaci 10-15 part, Rhizoma Zingiberis Preparatum 5-15 part, Rhizoma Atractylodis Macrocephalae (parched) 5-15 part, Cornu Cervi Degelatinatum 5-15 part, Radix Scutellariae 8-20 part, Fructus Schisandrae Chinensis 2-8 part.
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 20-40 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Radix Clematidis 20-30 part, Cortex Moutan 20-30 part, Ramulus Mori 20-30 part, Nidus Vespae 20-30 part, , Gekko Swinhonis 5-10 part, Cortex Eucommiae 20-30 part, Radix Linderae 20-30 part, Radix Notoginseng 30-40 part, Impatientis 50-70 part, Endothelium Corneum Gigeriae Galli 15-30 part, Sanguis Monopteri albi 15-25 part, Radix Angelicae Dahuricae 10-25 part, Ramulus Cinnamomi 10-25 part, Mylabris 5-15 part, Borneolum Syntheticum 10-30 part, Oleum sesami 2500-6000 part, Plumbum preparatium 800-1600 part.
Further preferred, pill for oral administration is made up of the medium-height grass raw material of following weight portion: Radix Bupleuri 16 parts, Rhizoma Cyperi 12 parts, Olibanum 12 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 11 parts, Radix Salviae Miltiorrhizae 18 parts, Squama Manis 11 parts, Rhizoma Curcumae 11 parts, Concha Ostreae 20 parts, 20 parts, Poria, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 10 parts, Radix Codonopsis 12 parts, king do not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 12 parts, Radix Asparagi 12 parts, Herba Taraxaci 12 parts, Rhizoma Zingiberis Preparatum 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, Cornu Cervi Degelatinatum 10 parts, Radix Scutellariae 10 parts, Fructus Schisandrae Chinensis 6 parts.
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 30 parts, Thallus Laminariae (Thallus Eckloniae) 25 parts, Radix Clematidis 25 parts, Cortex Moutan 25 parts, Ramulus Mori 25 parts, 25 parts, Nidus Vespae, Gekko Swinhonis 8 parts, the Cortex Eucommiae 25 parts, the Radix Linderae 25 parts, Radix Notoginseng 35 parts, Impatientis 58 parts, Endothelium Corneum Gigeriae Galli 20 parts, Sanguis Monopteri albi 15 parts, the Radix Angelicae Dahuricae 20 parts, Ramulus Cinnamomi 20 parts, Mylabris 10 parts, Borneolum Syntheticum 20 parts, Oleum sesami 4000 parts, 1200 parts, Plumbum preparatium.
Chinese medicine of the present invention according to the dialectical theory of the traditional Chinese medical science, in conjunction with primary disease due to feelings will do not relax, depression of liver-QI, deficiency of vital QI, QI-blood circulation are smooth and cause that the stagnation of QI, expectorant are solidifying, blood stasis, be condensed in breast, knot of fighting does not fall apart, and accumulating over a long period forms; Or worry impairing spleen, angry impairing the liver, feelings will is too drastic, causes liver spleen two wound, Chong and Ren channel disorder, so that the stagnation of QI, stagnation of phlegm, blood stasis is tied mutually and is brought out this disease in breast, therefore treats the method mediator yin-yang that primary disease must adopt depressed liver-energy dispersing and QI regulating, dissipating phlegm and resolving masses, blood circulation promoting and blood stasis dispelling, the kidney warming tonifying liver, invigorating the spleen and regulating the stomach, heat-clearing and toxic substances removing, makes human body blood vessels unobstructed rapidly, the heresy of expectorant, the stasis of blood is dispelled, the radical cure effect reach treating both the principal and secondary aspects of a disease, not easily recurring.
Take the function of each component of pill orally respectively:
Radix Bupleuri: reconciling superficies and interior, soothing the liver, yang invigorating, for cold, fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, micro-sweet, property is put down; Return liver, spleen, tri-jiao channel; Cure mainly promoting QI circulation for relieving depression, menstruction regulating and pain relieving.
Olibanum: blood-activating and qi-promoting pain relieving, detumescence life, resistance of becoming silted up puerperal, amenorrhea of stimulating the menstrual flow.
Radix Angelicae Sinensis: sweet in the mouth, enriches blood and invigorates blood circulation, and regulating menstruation relieves the pain, loosening bowel to relieve constipation, and for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, cold in blood is suffered from abdominal pain, dryness of the intestine constipation, rheumatalgia, traumatic injury.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping, changes and becomes silted up, dispersing the stagnated live-QI to relieve the stagnation of QI.
Radix Salviae Miltiorrhizae: invigorate blood circulation logical, removing heat from blood is subsided a swelling, and clear away heart-fire relieving restlessness, promoting blood circulation to remove blood stasis, sedation-analgesia, menoxenia, dysmenorrhea, metrorrhagia, mastitis, relieving mammary gland gall.
Squama Manis: the routed carbuncle of detumescence, searches wind active, stimulating milk secretion of stimulating the menstrual flow; Control carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea, galactostasis.
Rhizoma Curcumae: bitter in the mouth is pungent, warm in nature; Circulation of qi promoting, removing blood stasis, removing food stagnancy, pain relieving; Control trusted subordinate's distending pain, hundred abdominal masss, gather, and dyspepsia does not disappear, and women's blood stasis amenorrhea, traumatic injury is had a pain.
Concha Ostreae: salty, is slightly cold.Suppressing the hyperactive liver and subsiding YANG; Tranquillization with heavy prescription; Hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating; Cure mainly vertigo and tinnitus; Palpitation with fear insomnia, scrofula goiter, lump in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia.
Poria: sweet light is flat; Enter the heart, spleen, lung meridian; Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.
Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing, for menoxenia, amenorrhea of stimulating the menstrual flow, lochiorrhea, puerperal, blood closed.
Rhizoma Sparganii: acrid in the mouth, hardship, property is put down; Return liver, spleen channel controls lump in the abdomen, gather, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury; Cough due to lung-heat controlled by mongolian medicine, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease.
Bulbus Fritillariae Thunbergii: bitter in the mouth, cold in nature.Return lung, heart channel.There is removing heat-phlegm, the effects such as powder detoxifcation.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.
Spica Prunellae: liver heat removing eliminating stagnation, diuresis, antibacterial, blood pressure lowering, comfortable, resolving depression.
Radix Codonopsis: using tonifying Qi reinforcing lungs, supplementing QI for promoting the production of body fluid, anti-hypoxia, defying age, strengthens body immunity, anemia etc.
Semen Vaccariae: another name Wang Buliu, Vaccaria segetalis.For the dry seed of pinkwort Vaccaria segetalis, there is promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, expedite the emergence of the function of stimulating milk secretion; Cure mainly menoxenia, agalactosis, difficult labour, the diseases such as carbuncle furunculosis.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, for amenorrhea, dysmenorrhea, lochia , mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Radix Curcumae: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice etc., are usually used in amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge.
Radix Asparagi: nourshing Yin and drynsessmoistening prescription, cough-relieving of relieving inflammation or internal heat, deep blue treats mammary neoplasms, cyclomastopathy, pain in the lung, laryngopharynx swelling and pain.
Herba Taraxaci: heat-clearing and toxic substances removing, medicinal powder for relieving pain is tied, and antifungal, antitumor, to hyperpyrexia, mastalgia has good effect.
Rhizoma Zingiberis Preparatum: warming the meridian for stopping bleeding, warming middle-JIAO to relieve pain, loses blood for yang deficiency, tells nosebleed metrorrhagia, Deficiency and coldness of spleen and stomach, and stomachache is vomited and diarrhoea.
Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Cornu Cervi Degelatinatum: warming the kidney to activate YANG, astringing to arrest bleeding.For spleen kidney yang flaccidity, lack of appetite and vomiting, leucorrhea, enuresis frequent micturition, metrostaxis, carbuncle sucutaneous nodule.
Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, for hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Fructus Schisandrae Chinensis: astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.Control the deficiency of the lung to breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
The function of each component of Dressed plaster is respectively:
Myrrha: be used for the treatment of raw property or lymphatic temperament disease, as raw property arthralgia, sciatica, oral cavity pain, treatment soft tissue injury, treatment acute mastitis.
Thallus Laminariae (Thallus Eckloniae): antioxidation, anti-cancer, hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx.
Cortex Moutan: have another name called Cortex Moutan, clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.
Ramulus Mori: wind-damp dispelling, sharp joint, row aqueous vapor.Control anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.
Nidus Vespae: dispel the wind counteracting toxic substances, loose swollen pain relieving.For dental caries pain, carbuncle, the diseases such as scrofula is gone through, skin ulcer tinea.
Gekko Swinhonis: dispel the wind, active, eliminating stagnation.For paralysis due to windstroke, rheumatic arthritis, osteomyelitis, tuberculous lymphadenitis, tumor.
The Cortex Eucommiae: have another name called bakelite, has rubbish in purged body, strengthens human body cell substance metabolism, prevents muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol, reduces body fat, recovers blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic, stimulating central nervous system, improves leukocyte pharmacological action.
The Radix Linderae: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold, for QI stagnated by cold, chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia pain, through cold stomachache.
Radix Notoginseng: have another name called Radix Notoginseng, dissipating blood stasis stops blooding, subduing swelling and relieving pain.For various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling.
Impatientis: dispel the wind, invigorates blood circulation, detumescence, pain relieving.Control articular rheumatic pain, traumatic injury, scrofula carbuncle, furuncle.
Venenum Bufonis: removing toxic substances, pain relieving, refreshment of having one's ideas straightened out.For carbuncle furuncle, laryngopharynx swelling and pain, heatstroke coma, stomachache vomits and diarrhoea (can adopt 10 parts as required).
Endothelium Corneum Gigeriae Galli: invigorating the stomach and promoting digestion, arresting seminal emission, treating stranguria fossil.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of stranguria caused by urinary stone, gallbladder-distention hypochondriac pain.
Sanguis Monopteri albi: dispel the wind, invigorates blood circulation, tonifying YANG.Control facial hemiparalysis, otalgia, epistaxis, tinea, fistula.Wind is gone to invigorate blood circulation.Control the dry clonic spasm of the muscle of blood, external: coating or instillation ear, nose.For oral administration: to make ball with medicine.
The Radix Angelicae Dahuricae: expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.
Mylabris: this product is pungent loose poisonous product, energy treating the poisonous disease with poisonous drugs, dispersing swelling and dissipating binds.Control that carbuncle is swollen does not break firmly.
Borneolum Syntheticum: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
Oleum sesami: can lower three burnt pyretic toxicity, too fat to move, the growth muscle of disappearing, pain relieving, cure mainly too fat to move calentura, swat damage.
Plumbum preparatium: external detoxifying and relieving itching, convergence granulation promoting.
The preparation method that pill is taken in the present invention orally is:
Get each tcm components raw material by prescription proportioning, clean respectively and dry, pulverized 100-120 order and make powder, mix homogeneously, make the watered pill routinely, be Chinese medicine for oral administration ball of the present invention.
The present invention is taken pill orally and following methods can also be adopted to prepare:
Get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, and room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, gets supernatant, reclaims ethanol, the pH value of adjustment filtrate, is then condensed into extractum, adds adjuvant or the excipient of preparations shaping, preparations shaping, preferably prepares pellet, to obtain final product.
The preparation method of Dressed plaster of the present invention is as follows:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 3-5 day, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium enter oil receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment pour releasing fire-toxin 5-7 days in clear water into, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.
Chinese medicine using method of the present invention is:
First by Mammary proliferation position sterilized water or warm water, light salt brine wash clean, and wash with Chinese liquor or medicated wine and wipe, then by plaster fire or infrared ray bulb, coal gas burning things which may cause a fire disaster etc. roasting soft after be attached to affected part, often paste that can to apply 3-5 days is a course for the treatment of, general patient pastes with this plaster 1-5 separately, gets final product rehabilitation.Chinese medicine pill of the present invention takes 3 times, each 6-10 gram every day.General patient takes separately and can fully recover for 15-30 days.Chinese medicine pill of the present invention can with plaster with the use of, effect is better.The course of disease of general 2-10, for oral administration add external application 15-20 days and can fully recover, and there is no recurrence.
detailed description of the invention:
A kind of Chinese medicine composition of cyclomastopathy of oral administration and externally, wherein the ratio of each medicine of pill for oral administration is: Radix Bupleuri 15-20 part, Rhizoma Cyperi 10-15 part, Olibanum 10-15 part, Radix Angelicae Sinensis 15-18 part, Rhizoma Chuanxiong 10-12 part, Radix Salviae Miltiorrhizae 15-20 part, Squama Manis 10-15 part, Rhizoma Curcumae 10-15 part, Concha Ostreae 15-30 part, Poria 10-25 part, Herba Leonuri 10-20 part, Rhizoma Sparganii 9-15 part, Bulbus Fritillariae Thunbergii 5-15 part, Spica Prunellae 6-18 part, Radix Codonopsis 10-15 part, king does not stay 5-15 part, Flos Carthami 5-15 part, Radix Curcumae 10-15 part, Radix Asparagi 10-15 part, Herba Taraxaci 10-15 part, Rhizoma Zingiberis Preparatum 5-15 part, Rhizoma Atractylodis Macrocephalae (parched) 5-15 part, Cornu Cervi Degelatinatum 5-15 part, Radix Scutellariae 8-20 part, Fructus Schisandrae Chinensis 2-8 part,
The each medicine ratio of Dressed plaster is: Myrrha 20-40 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Radix Clematidis 20-30 part, Cortex Moutan 20-30 part, Ramulus Mori 20-30 part, Nidus Vespae 20-30 part, Gekko Swinhonis 5-10 part, Cortex Eucommiae 20-30 part, Radix Linderae 20-30 part, Radix Notoginseng 30-40 part, Impatientis 50-70 part, Endothelium Corneum Gigeriae Galli 15-30 part, Sanguis Monopteri albi 15-25 part, Radix Angelicae Dahuricae 10-25 part, Ramulus Cinnamomi 10-25 part, Mylabris 5-15 part, Borneolum Syntheticum 10-30 part, Oleum sesami 2500-6000 part, Plumbum preparatium 800-1600 part.
The preparation method that pill is taken in the present invention orally is:
Get each tcm components raw material by prescription proportioning, clean respectively and dry, pulverized 100-120 order and make powder, mix homogeneously, make the watered pill routinely, be Chinese medicine for oral administration ball of the present invention.
The present invention is taken pill orally and following methods can also be adopted to prepare:
Get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, add ethanol and reach ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, the pH value of adjustment filtrate, is then condensed into extractum, adds adjuvant or the excipient of preparations shaping, preparation becomes ball type, obtains pill for oral administration (can make pill or electuary as required).
The preparation method of Dressed plaster of the present invention is:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 120 orders to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use
3), by cataclasm for the medical material taken except Borneolum Syntheticum, Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 5-7 day, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " rear end pot is from fire;
5), get Plumbum preparatium enter oil receive cream, be stirred to clockwise " dripping into pearl " with willow rod, and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment pour releasing fire-toxin 5-7 days in clear water into, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.Obtain oral administration and externally Chinese medicine composition of the present invention.
With the using method of inside and outside combination application with cyclomastopathy: application mode is:
1) use in: by described Chinese medicine for oral administration ball or Chinese medicine preparation is oral takes: often Japan-Chinaly sooner or later take a ball or potion after meal;
2) external: first by Mammary proliferation position sterilized water or warm water, light salt brine wash clean, and wash with Chinese liquor or medicated wine and wipe, then by plaster fire or infrared ray bulb, coal gas burning things which may cause a fire disaster etc. roasting soft after be attached to affected part, often paste that can to apply 3-5 days is a course for the treatment of.
For showing the therapeutic effect of medicine of the present invention to cyclomastopathy, the present inventor to 300 routine case clinical observation, wherein male 25 people, women 275 people, 18 years old age--52 years old, the course of disease 2 months-8 years, by oral administration and externally used use medicine of the present invention, general medication 1-5 course for the treatment of, 268 people cure, cure rate reaches 96%, and 292 people are effective, and effective percentage is 98%.
Embodiment 1
Take raw material in proportion: wherein the ratio of each medicine of pill for oral administration is: Radix Bupleuri 15 parts, Rhizoma Cyperi 10 parts, Olibanum 10 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 15 parts, Squama Manis 10 parts, Rhizoma Curcumae 10 parts, Concha Ostreae 15 parts, 10 parts, Poria, Herba Leonuri 10 parts, Rhizoma Sparganii 9 parts, Bulbus Fritillariae Thunbergii 5 parts, Spica Prunellae 6 parts, Radix Codonopsis 10 parts, king does not stay 5 parts, 5 parts, Flos Carthami, Radix Curcumae 10 parts, Radix Asparagi 10 parts, Herba Taraxaci 10 parts, Rhizoma Zingiberis Preparatum 5 parts, Rhizoma Atractylodis Macrocephalae (parched) 5 parts, Cornu Cervi Degelatinatum 5 parts, Radix Scutellariae 8 parts, Fructus Schisandrae Chinensis 2 parts;
The each medicine ratio of Dressed plaster is: Myrrha 20 parts, Thallus Laminariae (Thallus Eckloniae) 20 parts, Radix Clematidis 20 parts, Cortex Moutan 20 parts, Ramulus Mori 20 parts, 20 parts, Nidus Vespae, Gekko Swinhonis 5 parts, the Cortex Eucommiae 20 parts, the Radix Linderae 20 parts, Radix Notoginseng 30 parts, Impatientis 50 parts, Endothelium Corneum Gigeriae Galli 15 parts, Sanguis Monopteri albi 15 parts, the Radix Angelicae Dahuricae 10 parts, Ramulus Cinnamomi 10 parts, Mylabris 5 parts, Borneolum Syntheticum 10 parts, Oleum sesami 2500 parts, 800 parts, Plumbum preparatium.
The preparation method that pill is taken in the present invention orally is:
Get each tcm components raw material by prescription proportioning, clean respectively and dry, pulverized 100-120 order and make powder, mix homogeneously, make the watered pill routinely, be Chinese medicine for oral administration ball of the present invention.
The preparation method of Dressed plaster of the present invention is:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 3-5 day, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium enter oil receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment pour releasing fire-toxin 5-7 days in clear water into, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.Obtain oral administration and externally Chinese medicine composition of the present invention.
Embodiment 2
Take raw material in proportion: the ratio of each crude drug of pill for oral administration is: Radix Bupleuri 20 parts, Rhizoma Cyperi 15 parts, Olibanum 15 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, 25 parts, Poria, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Radix Codonopsis 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Rhizoma Zingiberis Preparatum 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Cornu Cervi Degelatinatum 15 parts, Radix Scutellariae 20 parts, Fructus Schisandrae Chinensis 8 parts;
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 40 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Radix Clematidis 30 parts, Cortex Moutan 30 parts, Ramulus Mori 30 parts, 30 parts, Nidus Vespae, Gekko Swinhonis 10 parts, the Cortex Eucommiae 30 parts, the Radix Linderae 30 parts, Radix Notoginseng 40 parts, Impatientis 70 parts, Endothelium Corneum Gigeriae Galli 30 parts, Sanguis Monopteri albi 25 parts, the Radix Angelicae Dahuricae 25 parts, Ramulus Cinnamomi 25 parts, Mylabris 15 parts, Borneolum Syntheticum 30 parts, Oleum sesami 6000 parts, 1600 parts, Plumbum preparatium.
The preparation method that pill is taken in the present invention orally is:
Get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, and room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, gets supernatant, reclaims ethanol, the pH value of adjustment filtrate, is then condensed into extractum, adds adjuvant or the excipient of preparations shaping, make pellet, obtain pill for oral administration.
The preparation method of Dressed plaster of the present invention is:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 5, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium and enter oil and receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment to pour in clear water releasing fire-toxin into 7 days, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.Obtain oral administration and externally Chinese medicine composition of the present invention.
Embodiment 3
Take raw material in proportion: the ratio of each crude drug of pill for oral administration is: Radix Bupleuri 20 parts, Rhizoma Cyperi 15 parts, Olibanum 15 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, 25 parts, Poria, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Radix Codonopsis 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Rhizoma Zingiberis Preparatum 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Cornu Cervi Degelatinatum 15 parts, Radix Scutellariae 20 parts, Fructus Schisandrae Chinensis 8 parts;
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 40 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Radix Clematidis 30 parts, Cortex Moutan 30 parts, Ramulus Mori 30 parts, 30 parts, Nidus Vespae, Gekko Swinhonis 10 parts, the Cortex Eucommiae 30 parts, the Radix Linderae 30 parts, Radix Notoginseng 40 parts, Impatientis 70 parts, Endothelium Corneum Gigeriae Galli 30 parts, Sanguis Monopteri albi 25 parts, the Radix Angelicae Dahuricae 25 parts, Ramulus Cinnamomi 25 parts, Mylabris 15 parts, Borneolum Syntheticum 30 parts, Oleum sesami 6000 parts, 1600 parts, Plumbum preparatium.
The preparation method that pill is taken in the present invention orally is:
Get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, and room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, gets supernatant, reclaims ethanol, the pH value of adjustment filtrate, is then condensed into extractum, adds adjuvant or the excipient of preparations shaping, preparation becomes pellet, to obtain final product.
The preparation method of Dressed plaster of the present invention is:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 3-5 day, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium enter oil receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment pour releasing fire-toxin 5-7 days in clear water into, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.Obtain oral administration and externally Chinese medicine composition of the present invention.
Embodiment 4
Take raw material in proportion: pill for oral administration is made up of the medium-height grass raw material of following weight portion: Radix Bupleuri 16 parts, Rhizoma Cyperi 12 parts, Olibanum 12 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 11 parts, Radix Salviae Miltiorrhizae 18 parts, Squama Manis 11 parts, Rhizoma Curcumae 11 parts, Concha Ostreae 20 parts, 20 parts, Poria, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 10 parts, Radix Codonopsis 12 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 12 parts, Radix Asparagi 12 parts, Herba Taraxaci 12 parts, Rhizoma Zingiberis Preparatum 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, Cornu Cervi Degelatinatum 10 parts, Radix Scutellariae 10 parts, Fructus Schisandrae Chinensis 6 parts;
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 30 parts, Thallus Laminariae (Thallus Eckloniae) 25 parts, Radix Clematidis 25 parts, Cortex Moutan 25 parts, Ramulus Mori 25 parts, 25 parts, Nidus Vespae, Gekko Swinhonis 8 parts, the Cortex Eucommiae 25 parts, the Radix Linderae 25 parts, Radix Notoginseng 35 parts, Impatientis 58 parts, Endothelium Corneum Gigeriae Galli 20 parts, Sanguis Monopteri albi 15 parts, the Radix Angelicae Dahuricae 20 parts, Ramulus Cinnamomi 20 parts, Mylabris 10 parts, Borneolum Syntheticum 20 parts, Oleum sesami 4000 parts, 1200 parts, Plumbum preparatium.
The preparation method that pill is taken in the present invention orally is:
Get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, and room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, gets supernatant, reclaims ethanol, the pH value of adjustment filtrate, is then condensed into extractum, adds adjuvant or the excipient of preparations shaping, make pellet, obtain pill for oral administration.
The preparation method of Dressed plaster of the present invention is:
1), medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak 5, refining at a simmer, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium and enter oil and receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment to pour in clear water releasing fire-toxin into 7 days, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.Obtain oral administration and externally Chinese medicine composition of the present invention.
model case
Case 1
Lee so-and-so, female, 32 years old, suffer from cyclomastopathy 3 years, left breast had lump, two breast are swollen falls pain firmly, and there is hotness local, uses Chinese medicine of the present invention, Chinese medicine pill of the present invention for oral administration, and lump diminishes, disappearance, pain relief, visiting 2 times, treats 1 course for the treatment of with 3, plaster of the present invention, recovery from illness.
Case 2
Zhao, female, 38 years old, before 2 years, two breast suffered from cyclomastopathy, is showed no improvement through hospitalize, carried out the state of an illness more and more serious 2 years more, and lump in breast becomes large, two breast pendant pain.Use Chinese medicine for oral administration ball of the present invention to add a Dressed plaster 2-3 course for the treatment of, after about 25 days, breast lump disappears, and pain is removed, recovery from illness.The oral administration and externally that holds on is nursed one's health, not recurrence in 2 years.
Case 3
Lee so-and-so, man, 33 years old, suffers from cyclomastopathy 1 year half, and there is the lump of Semen arachidis hypogaeae size in left breast outside, the hurt like hell touched, touching pain increases the weight of, and within 12 days, has no improvement, with 3, plaster of the present invention through infusion treatment, 2 courses for the treatment of of further consultation afterwards, lump disappears, and pain is removed, recovery from illness.Coordinate pill for oral administration and external application, continue 2 courses for the treatment of of conditioning, not recurrence.
Case 4
Wang, female 40 years old, sick time 8 years, two newborn swelling pain, finds that there is lump in the recent period, menstruation the first seven within eight days, increase the weight of, unbearably, nipple can not touch clothing to two swelling of the breast pain, after anger more very.Be cyclomastopathy through this patient diagnosis, use Chinese medicine for oral administration ball of the present invention to add Dressed plaster all transference cures after 15 days, recovery from illness, adhere to taking innerlich anwenden ball, adopt oral administration and externally of the present invention combine, menstrual period, distending pain phenomenon disappeared completely, and 2 years do not recur.
Case 5
Zhang, female, 46 years old, mammary gland pain 5 years half on the left of primary symptom, nearly half a year increases the weight of, and mammary gland outside upper quadrant in left side can touch enclosed mass, and matter is hard, menoxenia, take 1 course for the treatment of of Chinese medicine of the present invention, 1 course for the treatment of of external application, distending pain obviously alleviates, continue external application 2 the symptom course for the treatment of to disappear completely, follow up a case by regular visits to 4 years after adhering to taking 2 courses for the treatment of without recurrence.
With clinical data, the specific embodiment of the present invention is described although above-mentioned in conjunction with the embodiments; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Claims (6)
1. the Chinese medicine composition of the cyclomastopathy of an oral administration and externally, it is characterized in that, comprise pill for oral administration and Dressed plaster, pill for oral administration is made up of the medium-height grass raw material of following weight portion: Radix Bupleuri 15-20 part, Rhizoma Cyperi 10-15 part, Olibanum 10-15 part, Radix Angelicae Sinensis 15-18 part, Rhizoma Chuanxiong 10-12 part, Radix Salviae Miltiorrhizae 15-20 part, Squama Manis 10-15 part, Rhizoma Curcumae 10-15 part, Concha Ostreae 15-30 part, Poria 10-25 part, Herba Leonuri 10-20 part, Rhizoma Sparganii 9-15 part, Bulbus Fritillariae Thunbergii 5-15 part, Spica Prunellae 6-18 part, Radix Codonopsis 10-15 part, king does not stay 5-15 part, Flos Carthami 5-15 part, Radix Curcumae 10-15 part, Radix Asparagi 10-15 part, Herba Taraxaci 10-15 part, Rhizoma Zingiberis Preparatum 5-15 part, Rhizoma Atractylodis Macrocephalae (parched) 5-15 part, Cornu Cervi Degelatinatum 5-15 part, Radix Scutellariae 8-20 part, Fructus Schisandrae Chinensis 2-8 part,
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 20-40 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Radix Clematidis 20-30 part, Cortex Moutan 20-30 part, Ramulus Mori 20-30 part, Nidus Vespae 20-30 part, , Gekko Swinhonis 5-10 part, Cortex Eucommiae 20-30 part, Radix Linderae 20-30 part, Radix Notoginseng 30-40 part, Impatientis 50-70 part, Endothelium Corneum Gigeriae Galli 15-30 part, Sanguis Monopteri albi 15-25 part, Radix Angelicae Dahuricae 10-25 part, Ramulus Cinnamomi 10-25 part, Mylabris 5-15 part, Borneolum Syntheticum 10-30 part, Oleum sesami 2500-6000 part, Plumbum preparatium 800-1600 part.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that, pill for oral administration is made up of the medium-height grass raw material of following weight portion: Radix Bupleuri 16 parts, Rhizoma Cyperi 12 parts, Olibanum 12 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 11 parts, Radix Salviae Miltiorrhizae 18 parts, Squama Manis 11 parts, Rhizoma Curcumae 11 parts, Concha Ostreae 20 parts, 20 parts, Poria, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 10 parts, Radix Codonopsis 12 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 12 parts, Radix Asparagi 12 parts, Herba Taraxaci 12 parts, Rhizoma Zingiberis Preparatum 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, Cornu Cervi Degelatinatum 10 parts, Radix Scutellariae 10 parts, Fructus Schisandrae Chinensis 6 parts,
Dressed plaster is made up of the raw material of Chinese medicine of following weight portion: Myrrha 30 parts, Thallus Laminariae (Thallus Eckloniae) 25 parts, Radix Clematidis 25 parts, Cortex Moutan 25 parts, Ramulus Mori 25 parts, 25 parts, Nidus Vespae, Gekko Swinhonis 8 parts, the Cortex Eucommiae 25 parts, the Radix Linderae 25 parts, Radix Notoginseng 35 parts, Impatientis 58 parts, Endothelium Corneum Gigeriae Galli 20 parts, Sanguis Monopteri albi 15 parts, the Radix Angelicae Dahuricae 20 parts, Ramulus Cinnamomi 20 parts, Mylabris 10 parts, Borneolum Syntheticum 20 parts, Oleum sesami 4000 parts, 1200 parts, Plumbum preparatium.
3. the preparation method of the Chinese medicine composition of the cyclomastopathy of oral administration and externally as claimed in claim 1 or 2, it is characterized in that, the preparation method of pill for oral administration is: get feed components for oral administration by prescription proportioning, clean respectively and dry, pulverized 100-120 order and make powder, mix homogeneously, makes the watered pill;
The preparation method of Dressed plaster is as follows:
1), external application medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 100-120 order to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use;
3), by cataclasm for the medical material taken except Borneolum Syntheticum and Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak the refining at a simmer of 3-5 day, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " turning off stove;
5), get Plumbum preparatium enter oil receive cream, stir clockwise, and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment pour releasing fire-toxin 5-7 days in clear water into, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.
4. the preparation method of the Chinese medicine composition of the cyclomastopathy of oral administration and externally as claimed in claim 1 or 2, it is characterized in that, pill for oral administration adopts following methods preparation: get each raw material by weight, by crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, add ethanol and reach ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, the pH value of adjustment filtrate, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparation becomes pellet, obtain pill for oral administration,
The preparation method of Dressed plaster is as follows:
1), external application medical material is taken by prescription proportioning for subsequent use;
2), by Plumbum preparatium pulverized 120 orders to be placed in iron pan slow fire fry to water to the greatest extent, loose be degree, for subsequent use
3), by cataclasm for the medical material taken except Borneolum Syntheticum, Sanguis Monopteri albi by prescription, enter iron pan Oleum sesami and soak refining at a simmer on the 5th, fry to the medicine oil that removes slag during coke yellow to obtain;
4), continue to add medicine of a warm nature oil to emitting white cigarette, " dripping into pearl " rear end pot is from fire;
5), get Plumbum preparatium and enter oil and receive cream, be stirred to clockwise " dripping into pearl ", and then add Borneolum Syntheticum, Sanguis Monopteri albi stir after ointment to pour in clear water releasing fire-toxin into 5 days, change water every day once;
6), ointment hot melt, be evenly spread out on the cloth that shears, often paste heavy 15 grams.
5. preparation method as claimed in claim 4, it is characterized in that, the concrete grammar of combination of inner and outside mode is:
1) use in: take oral for described Chinese medicine for oral administration ball: every Japan-China morning and evening takes a ball after meal;
2) external: first by Mammary proliferation position sterilized water or warm water, light salt brine wash clean, and wash with Chinese liquor or medicated wine and wipe, then plaster fire or infrared ray bulb are baked soft after be attached to affected part, often sticking 3-5 days is a course for the treatment of.
6. as the purposes of oral administration and externally Chinese medicine composition in treatment cyclomastopathy, breast tumor of claim 1 or 2.
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| CN201510368846.5A CN104971331A (en) | 2015-06-30 | 2015-06-30 | Orally-taken externally-applied traditional Chinese medicine composition for treating proliferation of mammary gland and preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106215093A (en) * | 2016-07-21 | 2016-12-14 | 魏晓兵 | A kind of Chinese medicine of external application for curing mammary gland pain |
| CN106421645A (en) * | 2016-10-19 | 2017-02-22 | 晋自俊 | Medicine for treating hyperplasia of mammary glands and ovarian cysts |
| CN109007996A (en) * | 2018-10-16 | 2018-12-18 | 天津艾安堂生物科技有限公司 | It is a kind of for alleviating the health-care bra of breast disease |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229357A (en) * | 2008-01-30 | 2008-07-30 | 胡永旺 | Chinese traditional medicine for treating mammary glands hyperplasia |
| CN102151325A (en) * | 2011-04-13 | 2011-08-17 | 苑学 | Traditional Chinese medicine for treating breast diseases |
| JP2013129637A (en) * | 2011-12-22 | 2013-07-04 | Kochi Univ | Gingerol-containing composition |
-
2015
- 2015-06-30 CN CN201510368846.5A patent/CN104971331A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229357A (en) * | 2008-01-30 | 2008-07-30 | 胡永旺 | Chinese traditional medicine for treating mammary glands hyperplasia |
| CN102151325A (en) * | 2011-04-13 | 2011-08-17 | 苑学 | Traditional Chinese medicine for treating breast diseases |
| JP2013129637A (en) * | 2011-12-22 | 2013-07-04 | Kochi Univ | Gingerol-containing composition |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106215093A (en) * | 2016-07-21 | 2016-12-14 | 魏晓兵 | A kind of Chinese medicine of external application for curing mammary gland pain |
| CN106421645A (en) * | 2016-10-19 | 2017-02-22 | 晋自俊 | Medicine for treating hyperplasia of mammary glands and ovarian cysts |
| CN106421645B (en) * | 2016-10-19 | 2020-01-07 | 晋自俊 | Medicine for treating hyperplasia of mammary glands and ovarian cyst |
| CN109007996A (en) * | 2018-10-16 | 2018-12-18 | 天津艾安堂生物科技有限公司 | It is a kind of for alleviating the health-care bra of breast disease |
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