CN105596997A - Menstrual disorder treatment medicine for oral administration and preparation method thereof - Google Patents

Menstrual disorder treatment medicine for oral administration and preparation method thereof Download PDF

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Publication number
CN105596997A
CN105596997A CN201610030035.9A CN201610030035A CN105596997A CN 105596997 A CN105596997 A CN 105596997A CN 201610030035 A CN201610030035 A CN 201610030035A CN 105596997 A CN105596997 A CN 105596997A
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medicine
menstrual disorder
stir
treatment
radix
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夏瑜
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/233Bupleurum
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and provides a menstrual disorder treatment medicine for oral administration according to the mechanism of traditional Chinese medical science to menstrual disorder. The menstrual disorder treatment medicine for oral administration comprises, by mass, 7.5-18 g of Radix Angelicae Sinensis, 15-28 g of Herba Leonuri, 6-13 g of Rhizoma Chuanxiong, 7.5-16 g of Rhizoma Cyperi (stir-fried), 7.5-26 g of Radix Salviae Miltiorrhizae, 4-8 g of stir-fried Radix bupleuri, 8-16 g of Cortex Moutan, 3-12 g of Radix Curcumae, 9-26 g of Radix Rehmanniae (carbonized), 5-10 g of Rhizoma Curcumae, 3-15 g of Flos Carthami, 9-15 g of Semen Persicae, 5-18 g of Radix Et Rhizoma Rhei and 6-18 g of Fructus Forsythiae. The menstrual disorder treatment medicine for oral administration has quick action and is a traditional Chinese medicine composition capable of treating both symptoms and root causes.

Description

A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine technical field, be specifically related to a kind of endo-medicine for the treatment of menstrual disorder, particularly for the field of endo-medicine of menstrual disorder patient and preparation method thereof.
Background technology
Menstrual disorder also claims irregular menstruation, is gynaecology's common disease, shows as the abnormal of menstrual cycle or amount of bleeding, stomachache and constitutional symptom can accompany month premenstrual, menstrual period time. The cause of disease may be organic disease or malfunction.
So, with regard to how finding a kind of medicine that can effectively treat menstrual disorder, be the problem that we should solve at present.
Summary of the invention
Along with the development of China's traditional Chinese medicine, in treatment menstrual disorder, people have recognized the advantage of the above-mentioned disease of Chinese traditional treatment gradually, and the advantages such as toxic and side effect is little in therapeutic process, expense is low, for the present situation of existing western medical treatment menstrual disorder, the object of the invention is to be to provide a kind of endo-medicine for the treatment of menstrual disorder, to solve menstrual disorder patient restorative problem early. This medicine is taking common Chinese medicine as raw material, has instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned menstrual disorder.
For reaching the object of foregoing invention, the technical solution adopted in the present invention is: a kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof is provided, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 7.5~18g, motherwort 15~28g, Ligusticum wallichii 6~13g, rhizoma cyperi (stir-fry) 7.5~16g, the red sage root 7.5~26g, fry radix bupleuri 4~8g, moutan bark 8~16g, root tuber of aromatic turmeric 3~12g,
Fresh rehmannia charcoal 9~26g, curcuma zedoary 5~10g, safflower 3~15g, peach kernel 9~15g, rheum officinale 5~18g, the capsule of weeping forsythia 6~18g.
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 8~16g, motherwort 16~25g, Ligusticum wallichii 7~12g, rhizoma cyperi (stir-fry) 8~14g, the red sage root 8~23g, stir-fry radix bupleuri 5~7g, moutan bark 9~14g, root tuber of aromatic turmeric 4~11g, fresh rehmannia charcoal 10~23g, curcuma zedoary 6~9g, safflower 4~14g, peach kernel 10~13g, rheum officinale 6~16g, the capsule of weeping forsythia 7~16g.
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, is characterized in that, each component of the medicine of described " preferred plan " and mass parts thereof are than as follows:
Radix Angelicae Sinensis 14g, motherwort 22g, Ligusticum wallichii 11g, rhizoma cyperi (stir-fry) 12g, red sage root 20g, stir-fry radix bupleuri 6g, moutan bark 12g, root tuber of aromatic turmeric 10g, fresh rehmannia charcoal 20g, curcuma zedoary 8g, safflower 12g, peach kernel 12g, rheum officinale 14g, capsule of weeping forsythia 14g.
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, is characterized in that, described method comprises the steps to be prepared from:
A, above-mentioned raw materials Chinese medicine is chosen respectively after decontamination and dust, decocted a drug wrapped than being ground into coarse grain shape respectively according to mass parts;
B, the raw material Chinese medicine of wrapping is put into cold boiling water soak 30 minutes, and then the clarified solution of soaked medicine and soak medicine is put into marmite in the lump, the cold boiling water that injected medicine 35mm decocts 40 minutes for the first time, after leaching liquid, the tepor boiling water that re-injected medicine 32mm decocts 35 minutes for the second time, and secondary mixes that to be condensed into 50% 540 milliliters of herb liquids for subsequent use.
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, is characterized in that, described instructions of taking is: the herb liquid preparing was taken with one day, every day potion, the morning, noon and afternoon service once, 180 milliliters/time of dosages, before meals, the 7-21 days that takes medicine, disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine. It is raw material that the present invention selects wherein modal Chinese medicine, gives full play to the pharmacological effect of each component:
Radix Angelicae Sinensis, nature and flavor: warm in nature, taste is sweet pungent, the effect that there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation, be used for the treatment of the deficiency of blood, sallow complexion, dizzy palpitaition, the deficiency of blood or have the stagnant irregular menstruation of the stasis of blood concurrently, through closing, the disease such as dysmenorrhoea, empty abdominal pain due to cold, coronary disease and angina pectoris, arthralgia due to wind-dampness, traumatic injury;
Motherwort, nature and flavor: taste is pungent, bitter, property micro-enter, there is effect of invigorate blood circulation, the dispel stasis of blood, menstruation regulating, the water that disappears, be used for the treatment of irregular menstruation, threatened abortion difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rush down blood, the disease such as the swollen sore of carbuncle;
Ligusticum wallichii, nature and flavor: pungent, warm, have that activating QI to alleviate the depression, method wind-dryness are wet, effect of promoting blood circulation and stopping pain, be used for the treatment of air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, through closing, difficult labour, postpartum stasis blocking piece pain, ulcer sores, irregular menstruation, lump in the abdomen suffer from abdominal pain, chest coerces the diseases such as shouting pain, tumbling and swelling, arthralgia due to wind-dampness;
Rhizoma cyperi (stir-fry), nature and flavor: pungent micro-hardship is sweet, flat, have effect of the Xie Yu of regulating the flow of vital energy, pain relieving menstruation regulating, are used for the treatment of that liver-stomach disharmony, depression of QI, chest abdomen side of body distending pain, phlegm and retained fluid ruffian are full, under irregular menstruation, uterine bleeding band;
The red sage root, nature and flavor: bitter, cold nature, there is disappear effect of carbuncle of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood, be used for the treatment of menoxenia, dysmenorrhoea, through closing, the stagnant stomachache of the stasis of blood in postpartum, trusted subordinate's pain, a lump in the abdomen causing distension and pain, hot numbness swells and ache, traumatic injury, heat enter the diseases such as ying blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore;
Fry radix bupleuri, nature and flavor: bitter, flat, there is harmonizing Sharyang, effect of relax liver and stomach, yang invigorating, be used for the treatment of fevers and chills alternate, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis, the invasion of blood chamber by heat;
Moutan bark, nature and flavor: arduous, cool, be slightly cold, there is effect of heat-clearing, promoting blood circulation to remove blood stasis, be used for the treatment of warm heat disease heat invading xuefen, send out spot, tell nosebleed, hot Fu Yin of germ later stage brimful of tears divides heating, deficiency of Yin osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhoea, carbuncle sore tumefacting virus, falls and flutter the disease such as the pain of injury, rheumatic fever numbness;
Root tuber of aromatic turmeric, nature and flavor: taste is pungent, bitter, cold in nature, thering is effect of invigorate blood circulation only energy, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, soothing liver-gallbladder, be used for the treatment of all pains of chest abdomen side of body rib, dysmenorrhes, through Bi, Disorder lump in the abdomen caking, pyreticosis coma, demented, shy the illnesss such as epilepsy, haematemesis, nosebleed are standby, blood pouring, sand pouring, jaundice;
Fresh rehmannia charcoal, nature and flavor: sweet, bitter, cold, there is effect of enriching yin, cool blood, be used for the treatment of fever due to yin deficiency, consumption of YIN caused by febrile disease, polydipsia, hectic fever due to yin, macula, tell the diseases such as the lower blood of nosebleed, menoxenia, fetal irritability;
Curcuma zedoary, nature and flavor: acrid, bitter, warm, there is broken blood gas, effect of the long-pending pain relieving that disappears, note of the ancient Chinese lump in the abdomen that is used for the treatment of caused by energy stagnation and blood stasis is gathered, trusted subordinate's turgor, stagnation of the circulation of vital energy dyspepsia, amenorrhoea dysmenorrhoea, traumatic injury etc.;
Safflower, nature and flavor: warm in nature, taste is pungent, has effect of activating blood to promote menstruation, blood stasis removing analgesic, be used for the treatment of through closing, dysmenorrhoea, traumatic injury, lochia, abdominal mass lump in the abdomen, hemorrhoid gall;
Peach kernel, nature and flavor: bitter sweet, flat, the effect of have the broken blood stasis of blood, moisturizing laxation gas, is used for the treatment of through Bi, Disorder lump in the abdomen, pyreticosis and holds blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood;
Rheum officinale, nature and flavor: bitter, cold, there is effect of the poison of purging heat, broken stagnant, row hemostasis, be used for the treatment of that real hot constipation, delirious speech send out that holder, dyspepsia ruffian are full, dysentery from the beginning of, tenesmus, stasis of blood menelipsis Bi, lumps in the chest and abdomen, time row hot epidemic disease, cruelly swelling ophthalmalgia, haematemesis, bleeding from five sense organs or subcutaneous tissue, yang jaundice, oedema, stranguria with turbid discharge, also urinate, the disease such as large carbuncle pyogenic infections, furunculosis, burn;
The capsule of weeping forsythia, nature and flavor: bitter, be slightly cold, there is effect clearing heat and detoxicating, dispersing swelling and dissipating binds, be used for the treatment of ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease from the beginning of, warmly join the army, high hot polydipsia, coma are sent out spot, heat is drenched renal shutdown.
Medicine of the present invention is the differentiation of disease and the dialectical principle combining based on Chinese traditional treatment menstrual disorder, think from pharmacological action and mechanism of action: with regard to menstrual disorder one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, and above-mentioned disease is had to good result for the treatment of.
Detailed description of the invention
The present invention is exactly a kind of Chinese medicine preparation proposing for the treatment of above-mentioned menstrual disorder, and the medicine effect that adopts this formula to prepare is good, and instant effect is a Chinese prescription for the treatment of both principal and secondary aspect of disease, and is particularly suitable for clinical use. Be described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 14g, motherwort 22g, Ligusticum wallichii 11g, rhizoma cyperi (stir-fry) 12g, red sage root 20g, stir-fry radix bupleuri 6g, moutan bark 12g, root tuber of aromatic turmeric 10g, fresh rehmannia charcoal 20g, curcuma zedoary 8g, safflower 12g, peach kernel 12g, rheum officinale 14g, capsule of weeping forsythia 14g.
Embodiment 2:
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 16g, motherwort 25g, Ligusticum wallichii 12g, rhizoma cyperi (stir-fry) 14g, red sage root 23g, stir-fry radix bupleuri 7g, moutan bark 14g, root tuber of aromatic turmeric 11g, fresh rehmannia charcoal 23g, curcuma zedoary 9g, safflower 14g, peach kernel 13g, rheum officinale 16g, capsule of weeping forsythia 16g.
Embodiment 3:
A kind of endo-medicine for the treatment of menstrual disorder and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 18g, motherwort 28g, Ligusticum wallichii 13g, rhizoma cyperi (stir-fry) 16g, red sage root 26g, stir-fry radix bupleuri 8g, moutan bark 16g, root tuber of aromatic turmeric 12g, fresh rehmannia charcoal 26g, curcuma zedoary 10g, safflower 15g, peach kernel 15g, rheum officinale 18g, capsule of weeping forsythia 18g.
Model case:
Through clinical diagnosis treatment menstrual disorder patient totally 120 examples, the age is 21 years old 68 above example, only has 52 examples for under-21. 116 examples of fully recovering in 120 routine patients, effective 4 examples, total effective rate reaches 100%. After treatment, menstruation recovery is normal, and sick announcement fully recovered.

Claims (3)

1. an endo-medicine for the treatment of menstrual disorder, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 7.5~18g, motherwort 15~28g, Ligusticum wallichii 6~13g, rhizoma cyperi (stir-fry) 7.5~16g, the red sage root 7.5~26g, stir-fry radix bupleuri 4~8g, moutan bark 8~16g, root tuber of aromatic turmeric 3~12g, fresh rehmannia charcoal 9~26g, curcuma zedoary 5~10g, safflower 3~15g, peach kernel 9~15g, rheum officinale 5~18g, the capsule of weeping forsythia 6~18g.
2. the endo-medicine for the treatment of menstrual disorder according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 8~16g, motherwort 16~25g, Ligusticum wallichii 7~12g, rhizoma cyperi (stir-fry) 8~14g, the red sage root 8~23g, stir-fry radix bupleuri 5~7g, moutan bark 9~14g, root tuber of aromatic turmeric 4~11g, fresh rehmannia charcoal 10~23g, curcuma zedoary 6~9g, safflower 4~14g, peach kernel 10~13g, rheum officinale 6~16g, the capsule of weeping forsythia 7~16g.
3. according to the endo-medicine of the treatment menstrual disorder described in claim 1 to 2, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Angelicae Sinensis 14g, motherwort 22g, Ligusticum wallichii 11g, rhizoma cyperi (stir-fry) 12g, red sage root 20g, stir-fry radix bupleuri 6g, moutan bark 12g, root tuber of aromatic turmeric 10g, fresh rehmannia charcoal 20g, curcuma zedoary 8g, safflower 12g, peach kernel 12g, rheum officinale 14g, capsule of weeping forsythia 14g.
CN201610030035.9A 2016-01-18 2016-01-18 Menstrual disorder treatment medicine for oral administration and preparation method thereof Withdrawn CN105596997A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816827A (en) * 2016-06-04 2016-08-03 陈福平 Traditional Chinese medicine for promoting menstruation
CN106692591A (en) * 2017-03-08 2017-05-24 王本晓 Traditional Chinese medicine composition for irregular menstruation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100232671B1 (en) * 1997-07-25 2000-02-01 김이현 Process for preparing the composition for treating gyncological disease and women's obesity
CN104147508A (en) * 2014-07-18 2014-11-19 甘保明 Traditional Chinese medicine composition for treating irregular menstruation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100232671B1 (en) * 1997-07-25 2000-02-01 김이현 Process for preparing the composition for treating gyncological disease and women's obesity
CN104147508A (en) * 2014-07-18 2014-11-19 甘保明 Traditional Chinese medicine composition for treating irregular menstruation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816827A (en) * 2016-06-04 2016-08-03 陈福平 Traditional Chinese medicine for promoting menstruation
CN106692591A (en) * 2017-03-08 2017-05-24 王本晓 Traditional Chinese medicine composition for irregular menstruation

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