CN106214939A - A kind of decoction medicine of osteoporosis disease and preparation method thereof - Google Patents

Abstract

nullThe invention belongs to technical field of Chinese medicine，Purpose is the decoction medicine of a kind of osteoporosis disease according to the traditional Chinese medical science, osteoporosis being recognized mechanism and providing，Each component of described medicine and mass parts ratio thereof are as follows: Radix Dipsaci 10～22g、Rhizoma Drynariae 15～25g、Radix Salviae Miltiorrhizae 8～16g、The Cortex Eucommiae 15～25g、Rhizoma Chuanxiong 5～12g、Radix Rehmanniae Preparata 20～45g、Radix Angelicae Pubescentis 5～16g、Herba Taxilli 15～32g、Radix Achyranthis Bidentatae 15～26g、The Rhizoma Anemarrhenae 10～26g、Fructus Lycii 10～20g、Poria 15～26g、Radix Clematidis 10～15g、Radix Glycyrrhizae 3～12g、Herba Lycopodii 15～26g、Herba speranskiae tuberculatae 15～26g、Radix Paeoniae Rubra 6～12g、Cortex erythrinae 10～20g、Radix Aconiti 15～25g、Radix Aconiti Kusnezoffii 6～9g、Radix Angelicae Sinensis 8～16g、The Rhizoma Atractylodis Macrocephalae 8～16g、Herba Asari 1.5～10g；The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of decoction medicine of osteoporosis disease and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, be specifically related to the decoction medicine of a kind of osteoporosis disease, particularly supply The field of the decoction medicine that patients with osteoporosis uses and preparation method thereof.

Background technology

Doctor thinks: osteoporosis (osteoporosis) is under the bone density and bone mass caused due to many reasons Fall, bone micro-structure destroys, causes bone fragility to increase, thus is susceptible to the general osteopathia of fracture.Osteoporosis is divided into former The property sent out and the big class of Secondary cases two.Primary osteoporosis is divided into again postmenopausal osteoporosis (I type), senile osteoporosis Disease (II type) and idiopathic osteoporosis (including juvenile) three kinds.Postmenopausal osteoporosis typically occurs in postmenopausal women In latter 5～10 years；Senile osteoporosis refers generally to the osteoporosis that old man occurred after 70 years old；And idiopathic osteoporosis master Occurring at teenager, the cause of disease is the most not clear.

So, just how to find a kind of medicine that can effectively treat above-mentioned osteoporosis, be that we are badly in need of solving at present Problem certainly.

Summary of the invention

Along with the development of China's Chinese medicine, in treatment osteoporosis, people gradually appreciate the traditional Chinese medical science The advantage treating above-mentioned osteoporosis, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, control for existing doctor trained in Western medicine Treat the present situation of above-mentioned osteoporosis, it is an object of the invention to the decoction medicine being to provide a kind of osteoporosis disease, to solve The certainly the most restorative problem of patients with osteoporosis.This medicine is with common Chinese medicine as raw material, has instant effect, curative effect The feature such as notable, and can effectively treat above-mentioned osteoporosis.

For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide a kind of osteoporosis disease Decoction medicine and preparation method thereof, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:

Radix Dipsaci 10～22g, Rhizoma Drynariae 15～25g, Radix Salviae Miltiorrhizae 8～16g, the Cortex Eucommiae 15～25g, Rhizoma Chuanxiong 5～12g, Radix Rehmanniae Preparata 20～45g, Radix Angelicae Pubescentis 5～16g, Herba Taxilli 15～32g, Radix Achyranthis Bidentatae 15～26g, the Rhizoma Anemarrhenae 10～26g, Fructus Lycii 10～20g, Poria 15～26g, Radix Clematidis 10～15g, Radix Glycyrrhizae 3～12g, Herba Lycopodii 15～26g, Herba speranskiae tuberculatae 15～26g, Radix Paeoniae Rubra 6～12g, Cortex erythrinae 10～ 20g, Radix Aconiti 15～25g, Radix Aconiti Kusnezoffii 6～9g, Radix Angelicae Sinensis 8～16g, the Rhizoma Atractylodis Macrocephalae 8～16g, Herba Asari 1.5～10g.

Decoction medicine of a kind of osteoporosis disease and preparation method thereof, it is characterised in that each component of described medicine And mass parts ratio is as follows:

Radix Dipsaci 15～20g, Rhizoma Drynariae 15～22g, Radix Salviae Miltiorrhizae 10～14g, the Cortex Eucommiae 18～22g, Rhizoma Chuanxiong 8～11g, Radix Rehmanniae Preparata 25～40g, Radix Angelicae Pubescentis 10～14g, Herba Taxilli 18～28g, Radix Achyranthis Bidentatae 18～23g, the Rhizoma Anemarrhenae 15～23g, Fructus Lycii 12～17g, Poria 18～ 23g, Radix Clematidis 11～13g, Radix Glycyrrhizae 8～11g, Herba Lycopodii 18～23g, Herba speranskiae tuberculatae 18～23g, Radix Paeoniae Rubra 8～11g, Cortex erythrinae 12 ～17g, Radix Aconiti 18～22g, Radix Aconiti Kusnezoffii 6～8g, Radix Angelicae Sinensis 10～14g, the Rhizoma Atractylodis Macrocephalae 10～14g, Herba Asari 3～9g.

Decoction medicine of a kind of osteoporosis disease and preparation method thereof, it is characterised in that the medicine of described " preferred plan " Each component of thing and mass parts ratio thereof are as follows:

Radix Dipsaci 17g, Rhizoma Drynariae 120g, Radix Salviae Miltiorrhizae 13g, Cortex Eucommiae 20g, Rhizoma Chuanxiong 10g, Radix Rehmanniae Preparata 35g, Radix Angelicae Pubescentis 13g, Herba Taxilli 25g, bosom cattle Knee joint 20g, Rhizoma Anemarrhenae 20g, Fructus Lycii 15g, Poria 20g, Radix Clematidis 12g, Radix Glycyrrhizae 10g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g, Radix Paeoniae Rubra 10g, Cortex erythrinae 15g, Radix Aconiti 20g, Radix Aconiti Kusnezoffii 7g, Radix Angelicae Sinensis 13g, Rhizoma Atractylodis Macrocephalae 13g, Herba Asari 8g.

Decoction medicine of a kind of osteoporosis disease and preparation method thereof, it is characterised in that described method includes walking as follows Suddenly it is prepared from:

A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be respectively crushed into coarse according to mass parts ratio and decoct a drug wrapped；

B, the raw material Chinese medicine wrapped is put in cold boiled water immersion half an hour, the most again by soaked medicine with soak medicine Marmite put in the lump by the clear liquor of thing, and the cold boiled water injecting medicine 35mm carries out decocting 45 minutes for the first time, after leaching medicinal liquid, The tepor boiled water re-injecting medicine 31mm carries out decocting 35 minutes for the second time, and secondary mixing is condensed into herb liquid 720 milli of 50% Rise standby.

Decoction medicine of a kind of osteoporosis disease and preparation method thereof, it is characterised in that described instructions of taking is: will system The herb liquid got ready divides two days to be taken, and sooner or later services once, dosage 180 milliliter/time, taking medicine before meal, takes medicine 120～180 days, disease Shape gradually alleviates or fully recovers.

Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:

Radix Dipsaci, nature and flavor: toil, tepor, there is effect of invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating, be used for treating aching pain in waist and back, foot knee joint The diseases such as unable, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer are swollen；

Rhizoma Drynariae, nature and flavor: bitter, warm, there is the kidney invigorating, the effect invigorated blood circulation, stop blooding, suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatism numbness for treatment Bitterly, the disease such as toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus；

Radix Salviae Miltiorrhizae, nature and flavor: bitter in the mouth, cold nature, there is blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, nourishing blood to tranquillize the mind, effect of removing heat from blood eliminating carbuncle, be used for Treatment menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, lump in the abdomen, pyretic arthralgia swell and ache, traumatic injury, Heat enters the diseases such as nutrient blood, dysphoria, vexed insomnia, ulcerative carbuncle toxic swelling；

The Cortex Eucommiae, nature and flavor: Gan Weixin, temperature, there is invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect, be used for treating spinal column ache, foot knee joint flaccidity Weak, dribbling urination, uncontrolled urination are itched, vaginal bleeding during pregnancy is intended to fall, the disease such as frequent fetal movement, hypertension；

Rhizoma Chuanxiong, nature and flavor: pungent, warm, have that activating QI to alleviate the depression, method wind-dryness be wet, effect of promoting blood circulation and stopping pain, be used for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores, menoxenia, amenorrhea dysmenorrhea, abdominal mass abdomen Bitterly, the breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia；

Radix Rehmanniae Preparata, nature and flavor: sweet, tepor, the effect there is YIN nourishing, enriching blood, be used for treating deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency, Seminal emission, metrorrhagia, menoxenia, quench one's thirst, the disease such as frequency of micturition, deafness, blurred vision；

Radix Angelicae Pubescentis, nature and flavor: arduous, warm, there is dispeling the wind, win wet, cold expelling, effect of pain relieving, be used for treating anemofrigid-damp arthralgia, the acid of waist knee joint Bitterly, the disease such as trick spasm and pain, chronic tracheitis, headache, toothache；

Herba Taxilli, nature and flavor: bitter sweet, flat, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, benefit blood, antiabortive effect, be used for The treatment disease such as soreness of waist and knee joint, muscles and bones flaccidity weak, hemiplegia, tinea pedis, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery；

Radix Achyranthis Bidentatae, nature and flavor: sweetness and bitterness acid, flat, there is life dissipating blood stasis blood, effect of subduing inflammation, control for treatment, gonorrhea, hematuria, warp Close, lump in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, waist knee joint The diseases such as osteodynia, spasm of the limbs, flaccidity syndrome and arthralgia syndrome；

The Rhizoma Anemarrhenae, nature and flavor: bitter in the mouth, cold in nature, there is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, effect of relieving restlessness of quenching the thirst, be used for treating epidemic febrile disease, High hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the diseases such as stranguria with turbid discharge of quenching one's thirst；

Fructus Lycii, nature and flavor: sweet, flat, there is effect of nourishing kidney, lung moistening, tonifying liver, improving eyesight, be used for treating hepatic and renal YIN deficiency, the acid of waist knee joint Soft, dizzy, dizzy, the many tear of blurred vision, cough due to consumptive disease, quench one's thirst, the disease such as seminal emission；

Poria, nature and flavor: sweet, light, flat, there is effect of eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, be used for treating dysuria, Edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, the disease such as seminal emission nebulousurine；

Radix Clematidis, nature and flavor: Xin Xian, temperature, poisonous, there is wind-damp dispelling, the meridian dredging, expectorant saliva, dissipate effect of the hypochondriac lump, be used for treating pain The diseases such as wind, insensitive impediment, chills and pain of the waist and kness, tinea pedis, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs；

Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, use In treatment asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, extremity contraction urgency pain, hysteria, cough and asthma, swelling throat Bitterly, ulcerative carbuncle swell and ache, infantile carbuncle and the disease such as medicine, alimentary toxicosis；

Herba Lycopodii, nature and flavor: toil, temperature, there is expelling wind and cold, dehumidifying detumescence, effect of relaxing muscles and tendons to promote blood circulation, be used for treating wind and cold wet The diseases such as numbness, joint aches, skin numbness, tetraparesis, edema, traumatic injury；

Herba speranskiae tuberculatae, nature and flavor: sweet in the mouth, nontoxic, have dispel the wind, dehumidify, relaxing muscles and tendons, invigorate blood circulation, effect of pain relieving, be used for treating rheumatism numbness Bitterly, the disease such as muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, skin ulcer tinea toxic swelling；

Radix Paeoniae Rubra, nature and flavor: bitter, be slightly cold, there is effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, be used for treating maculae caused by violent heat pathogen, hematemesis and epistaxis, The diseases such as discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, the accumulation of hernia abdominal mass, injury from falling down；

Cortex erythrinae, nature and flavor: toil, flat, there is effect of wind-damp dispelling, the meridian dredging, parasite killing, be used for treating rheumatic arthralgia, dysentery, tooth Bitterly, the disease such as scabies；

Radix Aconiti, nature and flavor: pungent, bitter, hot, very toxic, there is effect of expelling wind and removing dampness, antalgic, be used for treating anemofrigid-damp arthralgia, pass Joint pain, trusted subordinate's cold type of pain, colic of cold type such as are had a pain the disease；

Radix Aconiti Kusnezoffii, nature and flavor: pungent, bitter, hot, very toxic, there is effect of expelling wind and cold, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling, be used for treating wind The diseases such as cold-damp numbness, deadly cold hand and foot, traumatic injury, sore；

Radix Angelicae Sinensis, nature and flavor: Gan Xin, temperature, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, be used for treating menoxenia, Amenorrhea stomachache, lump in the abdomen knot are poly-, metrorrhagia, headache due to deficiency of blood, dizziness, flaccidity syndrome and arthralgia syndrome, dryness of the intestine dyschezia, weight after bloody dysentery, carbuncle skin ulcer are stolen, injury from falling down Deng disease；

The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter sweet, warm, have spleen reinforcing, stomach reinforcing, dampness and in, antiabortive effect, be used for treating deficient QI of the spleen and stomach, no Think diet, asthenia few gas, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea are uneasy Disease；

Herba Asari, nature and flavor: pungent, warm, have dispel the wind, cold expelling, Hang Shui, the effect having one's ideas straightened out, be used for treating air-cooled headache, nasal sinusitis, toothache, The diseases such as phlegm retention cough with dyspnea, rheumatic arthralgia.

Medicine of the present invention is differential diagnosis of diseases based on traditional Chinese medical science osteoporosis disease and the dialectical principle combined, from pharmacological action and Mechanism of action is thought: with regard to osteoporosis, each raw material herbal medicine efficacy in medicine provided by the present invention is played, altogether to above-mentioned disease There is good therapeutic effect.

Detailed description of the invention

The present invention is aiming at the treatment of above-mentioned osteoporosis and a kind of Chinese medicine formula of proposing, uses this formula to prepare Medicine effect good, instant effect, be the Chinese prescription of a treating both the principal and secondary aspects of a disease, be particularly suitable for Clinical practice.Below in conjunction with the present invention Detailed description of the invention be described in further detail:

Embodiment 1:

The decoction medicine of a kind of osteoporosis disease, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows Shown in:

Radix Dipsaci 17g, Rhizoma Drynariae 20g, Radix Salviae Miltiorrhizae 13g, Cortex Eucommiae 20g, Rhizoma Chuanxiong 10g, Radix Rehmanniae Preparata 35g, Radix Angelicae Pubescentis 13g, Herba Taxilli 25g, bosom cattle Knee joint 20g, Rhizoma Anemarrhenae 20g, Fructus Lycii 15g, Poria 20g, Radix Clematidis 12g, Radix Glycyrrhizae 10g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g, Radix Paeoniae Rubra 10g, Cortex erythrinae 15g, Radix Aconiti 20g, Radix Aconiti Kusnezoffii 7g, Radix Angelicae Sinensis 13g, Rhizoma Atractylodis Macrocephalae 13g, Herba Asari 8g.

Embodiment 2:

The decoction medicine of a kind of osteoporosis disease, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows Shown in:

Radix Dipsaci 20g, Rhizoma Drynariae 22g, Radix Salviae Miltiorrhizae 14g, Cortex Eucommiae 22g, Rhizoma Chuanxiong 11g, Radix Rehmanniae Preparata 40g, Radix Angelicae Pubescentis 14g, Herba Taxilli 28g, bosom cattle Knee joint 23g, Rhizoma Anemarrhenae 23g, Fructus Lycii 17g, Poria 23g, Radix Clematidis 13g, Radix Glycyrrhizae 11g, Herba Lycopodii 23g, Herba speranskiae tuberculatae 23g, Radix Paeoniae Rubra 11g, Cortex erythrinae 17g, Radix Aconiti 22g, Radix Aconiti Kusnezoffii 8g, Radix Angelicae Sinensis 14g, Rhizoma Atractylodis Macrocephalae 14g, Herba Asari 9g.

Embodiment 3:

The decoction medicine of a kind of osteoporosis disease, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows Shown in:

Radix Dipsaci 22g, Rhizoma Drynariae 25g, Radix Salviae Miltiorrhizae 16g, Cortex Eucommiae 25g, Rhizoma Chuanxiong 12g, Radix Rehmanniae Preparata 45g, Radix Angelicae Pubescentis 16g, Herba Taxilli 32g, bosom cattle Knee joint 26g, Rhizoma Anemarrhenae 26g, Fructus Lycii 20g, Poria 26g, Radix Clematidis 15g, Radix Glycyrrhizae 12g, Herba Lycopodii 26g, Herba speranskiae tuberculatae 26g, Radix Paeoniae Rubra 12g, Cortex erythrinae 20g, Radix Aconiti 25g, Radix Aconiti Kusnezoffii 9g, Radix Angelicae Sinensis 16g, Rhizoma Atractylodis Macrocephalae 16g, Herba Asari 10g.

Model case:

Through clinical conditions patients with osteoporosis totally 260 example, the age is 155 examples of more than 71 years old, and only 105 examples are 71 years old Below.215 examples of recovery from illness in 260 example patients, 45 effective examples, total effective rate reaches 100%.Through treatment after, symptom gradually alleviate or Recovery from illness.

Claims (3)

1. the decoction medicine of an osteoporosis disease, it is characterised in that each component of described medicine and mass parts thereof are such as Shown in lower:

Radix Dipsaci 10～22g, Rhizoma Drynariae 15～25g, Radix Salviae Miltiorrhizae 8～16g, the Cortex Eucommiae 15～25g, Rhizoma Chuanxiong 5～12g, Radix Rehmanniae Preparata 20～45g, Radix Angelicae Pubescentis 5～16g, Herba Taxilli 15～32g, Radix Achyranthis Bidentatae 15～26g, the Rhizoma Anemarrhenae 10～26g, Fructus Lycii 10～20g, Poria 15～26g, Radix Clematidis 10～15g, Radix Glycyrrhizae 3～12g, Herba Lycopodii 15～26g, Herba speranskiae tuberculatae 15～26g, Radix Paeoniae Rubra 6～12g, Cortex erythrinae 10～ 20g, Radix Aconiti 15～25g, Radix Aconiti Kusnezoffii 6～9g, Radix Angelicae Sinensis 8～16g, the Rhizoma Atractylodis Macrocephalae 8～16g, Herba Asari 1.5～10g.

The decoction medicine of a kind of osteoporosis disease the most according to claim 1, it is characterised in that each of described medicine Component and mass parts ratio thereof are as follows:

Radix Dipsaci 15～20g, Rhizoma Drynariae 15～22g, Radix Salviae Miltiorrhizae 10～14g, the Cortex Eucommiae 18～22g, Rhizoma Chuanxiong 8～11g, Radix Rehmanniae Preparata 25～40g, Radix Angelicae Pubescentis 10～14g, Herba Taxilli 18～28g, Radix Achyranthis Bidentatae 18～23g, the Rhizoma Anemarrhenae 15～23g, Fructus Lycii 12～17g, Poria 18～ 23g, Radix Clematidis 11～13g, Radix Glycyrrhizae 8～11g, Herba Lycopodii 18～23g, Herba speranskiae tuberculatae 18～23g, Radix Paeoniae Rubra 8～11g, Cortex erythrinae 12 ～17g, Radix Aconiti 18～22g, Radix Aconiti Kusnezoffii 6～8g, Radix Angelicae Sinensis 10～14g, the Rhizoma Atractylodis Macrocephalae 10～14g, Herba Asari 3～9g.

3. according to the decoction medicine of a kind of osteoporosis disease described in claim 1 to 2, it is characterised in that described medicine Each component and mass parts ratio thereof are as follows:

Radix Dipsaci 17g, Rhizoma Drynariae 120g, Radix Salviae Miltiorrhizae 13g, Cortex Eucommiae 20g, Rhizoma Chuanxiong 10g, Radix Rehmanniae Preparata 35g, Radix Angelicae Pubescentis 13g, Herba Taxilli 25g, bosom cattle Knee joint 20g, Rhizoma Anemarrhenae 20g, Fructus Lycii 15g, Poria 20g, Radix Clematidis 12g, Radix Glycyrrhizae 10g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g, Radix Paeoniae Rubra 10g, Cortex erythrinae 15g, Radix Aconiti 20g, Radix Aconiti Kusnezoffii 7g, Radix Angelicae Sinensis 13g, Rhizoma Atractylodis Macrocephalae 13g, Herba Asari 8g.