CN106109572A - One treats osteoporotic Chinese medicine composition and preparation method thereof - Google Patents

One treats osteoporotic Chinese medicine composition and preparation method thereof Download PDF

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Publication number
CN106109572A
CN106109572A CN201610812375.7A CN201610812375A CN106109572A CN 106109572 A CN106109572 A CN 106109572A CN 201610812375 A CN201610812375 A CN 201610812375A CN 106109572 A CN106109572 A CN 106109572A
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chinese medicine
medicine composition
rhizoma
radix
osteoporotic
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Chengdu Feilong Water Treatment Technology Institute
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    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

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Abstract

The invention belongs to technical field of Chinese medicine, purpose is that the one provided osteoporotic understanding mechanism according to the traditional Chinese medical science treats osteoporotic Chinese medicine composition, each component of described Chinese medicine composition and mass parts ratio thereof are as follows: Herba Epimedii 5~15g, the Cortex Eucommiae 15~25g, Radix Dipsaci 10~22g, Rhizoma Chuanxiong 5~12g, Radix Achyranthis Bidentatae 15~28g, Rhizoma Drynariae 15~26g, Placenta Hominis 4~10g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Salviae Miltiorrhizae 8~16g, starch is appropriate;The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

One treats osteoporotic Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to one and treat osteoporotic Chinese medicine composition, particularly The field of the Chinese medicine composition for sufferers of osteoporosis face and preparation method thereof.
Background technology
Doctor thinks: osteoporosis (osteoporosis) is under the bone density and bone mass caused due to many reasons Fall, bone micro-structure destroys, causes bone fragility to increase, thus is susceptible to the general osteopathia of fracture.Osteoporosis is divided into former The property sent out and the big class of Secondary cases two.Primary osteoporosis is divided into again postmenopausal osteoporosis (I type), senile osteoporosis Disease (II type) and idiopathic osteoporosis (including juvenile) three kinds.Postmenopausal osteoporosis typically occurs in postmenopausal women In latter 5~10 years;Senile osteoporosis refers generally to the osteoporosis that old man occurred after 70 years old;And idiopathic osteoporosis master Occurring at teenager, the cause of disease is the most not clear.
So, with regard to how finding one can effectively treat above-mentioned osteoporotic Chinese medicine composition, it is that we are badly in need of at present Problem to be solved.
Summary of the invention
Along with the development of China's Chinese medicine, in treatment osteoporosis, people gradually appreciate middle treatment Treat above-mentioned osteoporotic advantage, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, on existing western medical treatment State osteoporotic present situation, it is an object of the invention to be to provide one to treat osteoporotic Chinese medicine composition, to solve bone Matter is loosened the most restorative problem of patient.This medicine is with common Chinese medicine as raw material, has instant effect, evident in efficacy etc. Feature, and can effectively treat above-mentioned osteoporosis.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide one to treat osteoporotic Chinese medicine composition and preparation method thereof, it is characterised in that each component of described Chinese medicine composition and mass parts thereof are than following institute Show:
Herba Epimedii 5~15g, the Cortex Eucommiae 15~25g, Radix Dipsaci 10~22g, Rhizoma Chuanxiong 5~12g, Radix Achyranthis Bidentatae 15~28g, Rhizoma Drynariae 15~ 26g, Placenta Hominis 4~10g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Salviae Miltiorrhizae 8~16g, starch is appropriate.
One treats osteoporotic Chinese medicine composition and preparation method thereof, it is characterised in that described Chinese medicine composition Each component and mass parts ratio thereof are as follows:
Herba Epimedii 10~13g, the Cortex Eucommiae 18~22g, Radix Dipsaci 15~20g, Rhizoma Chuanxiong 8~11g, Radix Achyranthis Bidentatae 18~25g, Rhizoma Drynariae 18~ 23g, Placenta Hominis 6~9g, the Rhizoma Atractylodis Macrocephalae 10~14g, Radix Salviae Miltiorrhizae 10~14g, starch is appropriate.
One treats osteoporotic Chinese medicine composition and preparation method thereof, it is characterised in that described " preferred plan " Each component of Chinese medicine composition and mass parts ratio thereof are as follows:
Herba Epimedii 12g, Cortex Eucommiae 20g, Radix Dipsaci 17g, Rhizoma Chuanxiong 10g, Radix Achyranthis Bidentatae 22g, Rhizoma Drynariae 20g, Placenta Hominis 8g, Rhizoma Atractylodis Macrocephalae 113g, pellet Ginseng 13g, starch is appropriate.
One treats osteoporotic Chinese medicine composition and preparation method thereof, it is characterised in that described method includes as follows Step is prepared from:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked decontamination and dust, be ground into superfine end according to mass parts ratio stand-by;
B, the method preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch being sieved, put into medicine device Middle mixing is mixed all, and (granularity of its watered pill is: 4.8mm-5.0mm), and then dry, and sealed packaging is i.e. to be then prepared as watered pill Can.
One treats osteoporotic Chinese medicine composition and preparation method thereof, it is characterised in that described instructions of taking is: will The watered pill medicine prepared is taken with every twice-daily, sooner or later services once, and dosage 2g/time, taking medicine before meal (send by warm water Under), to take medicine 120~186 days, symptom gradually alleviates or fully recovers.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Herba Epimedii, nature and flavor: Xin Gan, temperature, there is effect of kidney invigorating and YANG supporting, expelling wind and removing dampness, be used for treating sexual impotence do not lift, urine leaching The disease such as drip, muscles and bones contraction urgency, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless;
The Cortex Eucommiae, nature and flavor: Gan Weixin, temperature, there is invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect, be used for treating spinal column ache, foot knee joint flaccidity Weak, dribbling urination, uncontrolled urination are itched, vaginal bleeding during pregnancy is intended to fall, the disease such as frequent fetal movement, hypertension;
Radix Dipsaci, nature and flavor: bitter in the mouth, pungent, slightly warm in nature, there is invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, effect of only metrorrhagia, be used for treating waist The back of the body is ached, podomere flaccidity syndrome and arthralgia syndrome, fall and flutter wound, damage the diseases such as muscle folding bone, fetal movement red, the metrorrhagia of leakage, seminal emission, leukorrhagia, carbuncle skin ulcer be swollen;
Rhizoma Chuanxiong, nature and flavor: pungent, warm, have that activating QI to alleviate the depression, method wind-dryness be wet, effect of promoting blood circulation and stopping pain, be used for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores, menoxenia, amenorrhea dysmenorrhea, abdominal mass abdomen Bitterly, the breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia;
Radix Achyranthis Bidentatae, nature and flavor: sweetness and bitterness is sour, flat, has life dissipating blood stasis blood, effect of subduing inflammation, is used for treating gonorrhea, hematuria, amenorrhea, disease Abdominal mass, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, invigorating the liver and kidney, bone and muscle strengthening, control waist kneecap pain, four The diseases such as limb contracture, flaccidity syndrome and arthralgia syndrome;
Rhizoma Drynariae, nature and flavor: bitter, warm, there is the kidney invigorating, the effect invigorated blood circulation, stop blooding, suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatism numbness for treatment Bitterly, the disease such as toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus;
Placenta Hominis, nature and flavor: Gan Xian, temperature, have QI invigorating, nourish blood, effect of benefit essence, be used for treating deficient, weakness and emaciation, consumptive fever hectic fever due to YIN-deficiency, Cough with asthma, spitting of blood, night sweat, seminal emission, sexual impotence, women's vim and vigour are not enough, the infertile or newborn disease such as few;
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter sweet, warm, have spleen reinforcing, stomach reinforcing, dampness and in, antiabortive effect, be used for treating deficient QI of the spleen and stomach, no Think diet, asthenia few gas, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea are uneasy Disease;
Radix Salviae Miltiorrhizae, nature and flavor: bitter, tepor, there is effect of blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving, be used for treating angina pectoris, the moon Through the disease such as uncomfortable, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, lump in the abdomen, accumulation, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Medicine of the present invention is based on the osteoporotic differential diagnosis of diseases of Chinese traditional treatment and the dialectical principle combined, from pharmacological action and Mechanism of action is thought: with regard to osteoporosis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has above-mentioned disease Well therapeutic effect.
Detailed description of the invention
A kind of Chinese medicine formula that the present invention is aiming at above-mentioned osteoporotic treatment and proposes, uses this formula to prepare Medicine effect is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Below in conjunction with the present invention's Detailed description of the invention is described in further detail:
Embodiment 1:
One treats osteoporotic Chinese medicine composition, it is characterised in that each component of described Chinese medicine composition and quality thereof Part ratio is as follows:
Herba Epimedii 12g, Cortex Eucommiae 20g, Radix Dipsaci 17g, Rhizoma Chuanxiong 10g, Radix Achyranthis Bidentatae 22g, Rhizoma Drynariae 20g, Placenta Hominis 8g, Rhizoma Atractylodis Macrocephalae 113g, pellet Ginseng 13g, starch is appropriate.
Embodiment 2:
One treats osteoporotic Chinese medicine composition, it is characterised in that each component of described Chinese medicine composition and quality thereof Part ratio is as follows:
Herba Epimedii 13g, Cortex Eucommiae 22g, Radix Dipsaci 20g, Rhizoma Chuanxiong 11g, Radix Achyranthis Bidentatae 25g, Rhizoma Drynariae 23g, Placenta Hominis 9g, Rhizoma Atractylodis Macrocephalae 14g, Radix Salviae Miltiorrhizae 14g, starch is appropriate.
Embodiment 3:
One treats osteoporotic Chinese medicine composition, it is characterised in that each component of described Chinese medicine composition and quality thereof Part ratio is as follows:
Herba Epimedii 15g, Cortex Eucommiae 25g, Radix Dipsaci 22g, Rhizoma Chuanxiong 12g, Radix Achyranthis Bidentatae 28g, Rhizoma Drynariae 26g, Placenta Hominis 10g, Rhizoma Atractylodis Macrocephalae 16g, pellet Ginseng 16g, starch is appropriate.
Model case:
Through clinical conditions sufferers of osteoporosis face totally 280 example, the age is 165 examples of more than 70 years old, only 115 examples be 70 years old with Under.230 examples of recovery from illness in 280 example patients, 50 effective examples, total effective rate reaches 100%.After treatment, symptom gradually alleviates or fullys recover from an illness More.

Claims (3)

1. treat osteoporotic Chinese medicine composition for one kind, it is characterised in that each component of described Chinese medicine composition and matter thereof Amount part ratio is as follows:
Herba Epimedii 5~15g, the Cortex Eucommiae 15~25g, Radix Dipsaci 10~22g, Rhizoma Chuanxiong 5~12g, Radix Achyranthis Bidentatae 15~28g, Rhizoma Drynariae 15~ 26g, Placenta Hominis 4~10g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Salviae Miltiorrhizae 8~16g, starch is appropriate.
The osteoporotic Chinese medicine composition for the treatment of the most according to claim 1, it is characterised in that described Chinese medicine composition Each component and mass parts ratio thereof are as follows:
Herba Epimedii 10~13g, the Cortex Eucommiae 18~22g, Radix Dipsaci 15~20g, Rhizoma Chuanxiong 8~11g, Radix Achyranthis Bidentatae 18~25g, Rhizoma Drynariae 18~ 23g, Placenta Hominis 6~9g, the Rhizoma Atractylodis Macrocephalae 10~14g, Radix Salviae Miltiorrhizae 10~14g, starch is appropriate.
3. according to the osteoporotic Chinese medicine composition of the treatment described in claim 1 to 2, it is characterised in that described Chinese medicine composition Each component of thing and mass parts ratio thereof are as follows:
Herba Epimedii 12g, Cortex Eucommiae 20g, Radix Dipsaci 17g, Rhizoma Chuanxiong 10g, Radix Achyranthis Bidentatae 22g, Rhizoma Drynariae 20g, Placenta Hominis 8g, Rhizoma Atractylodis Macrocephalae 113g, pellet Ginseng 13g, starch is appropriate.
CN201610812375.7A 2016-09-09 2016-09-09 One treats osteoporotic Chinese medicine composition and preparation method thereof Withdrawn CN106109572A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596058A (en) * 2017-09-07 2018-01-19 成都兴倍加生物科技有限责任公司 It is a kind of effectively to treat endo-medicine of osteoporosis and preparation method thereof
CN107596102A (en) * 2017-09-07 2018-01-19 成都兴倍加生物科技有限责任公司 A kind of granules medicine for treating osteoporosis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596058A (en) * 2017-09-07 2018-01-19 成都兴倍加生物科技有限责任公司 It is a kind of effectively to treat endo-medicine of osteoporosis and preparation method thereof
CN107596102A (en) * 2017-09-07 2018-01-19 成都兴倍加生物科技有限责任公司 A kind of granules medicine for treating osteoporosis and preparation method thereof

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