CN113925951B - Thuja orientalis traditional Chinese medicine extract, extraction method thereof and application of thuja orientalis traditional Chinese medicine extract in hair washing and caring products - Google Patents

Thuja orientalis traditional Chinese medicine extract, extraction method thereof and application of thuja orientalis traditional Chinese medicine extract in hair washing and caring products Download PDF

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CN113925951B
CN113925951B CN202111395393.7A CN202111395393A CN113925951B CN 113925951 B CN113925951 B CN 113925951B CN 202111395393 A CN202111395393 A CN 202111395393A CN 113925951 B CN113925951 B CN 113925951B
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杨楠
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/9783Angiosperms [Magnoliophyta]
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    • A61Q5/02Preparations for cleaning the hair
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    • A61Q5/12Preparations containing hair conditioners
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
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    • B01D3/02Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in boilers or stills
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
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Abstract

The invention discloses a thuja Chinese medicine extract, an extraction method thereof and application thereof in hair washing and caring products. The extract is prepared from Thuja, rhizoma Zingiberis recens, fructus Gleditsiae Abnormalis, tea seed cake, polygoni Multiflori radix, fructus Sapindi Mukouossi, radix astragali, folium Platycladi, kochiae fructus, cortex Dictamni Radicis, radix Sophorae Flavescentis and Saviae Miltiorrhizae radix. The extraction method comprises the following steps: 1) Soaking Thuja orientalis in water in a distillation pot, boiling, distilling, and separating oil from water to obtain Thuja orientalis essential oil and hydrolat, wherein the obtained essential oil is component A; 2) Filtering the material liquid in the distillation still, introducing the filtrate into an extraction tank, adding other raw material components into the extraction tank, decocting, filtering, mixing the filtrate with the pure dew, and concentrating to obtain fluid extract as component B. The thuja Chinese medicinal extract and hair washing and caring product containing the same have pleasant fragrance, and can control oil, remove dandruff, promote hair growth, and strengthen hair, and effectively inhibit alopecia, especially seborrheic alopecia.

Description

Arborvitae traditional Chinese medicine extract, extraction method thereof and application of arborvitae traditional Chinese medicine extract in hair washing and caring products
Technical Field
The invention belongs to the technical field of natural plant extracts, and particularly relates to a thuja traditional Chinese medicine extract, an extraction method thereof and application thereof in hair washing and caring products.
Background
Thuja (Thuja Sutchuenensis) is evergreen arbor of Thuja (Thuja) of Cupressaceae, and is an "activated stone" originated from dinosaur age. Researches show that root, stem and leaf of Thuja contains terpenoids such as thujopside, alpha-pinene, limonene, etc., and the terpenoids have good lipid solubility and small molecule, and have antibacterial, antioxidant, antitumor, blood pressure lowering, anthelmintic, antiinflammatory, diuretic, phlegm eliminating, body building and body strengthening effects. In recent years, artificial planting tests of thuja have been performed and succeeded, providing conditions for research and development of thuja.
Pathological hair loss refers to abnormal or excessive loss of hair for a number of reasons. Currently the most common pathologic alopecia is seborrheic alopecia. Seborrheic alopecia is also called androgenetic alopecia, and progressive alopecia of forehead, temporalis and top begins to appear generally around 20 years old. Both men and women occur, but more commonly male patients. The clinical manifestations of seborrheic alopecia are: the initial stage is often itchy, a large amount of hair falls off when scratching or combing the hair, the hair roots of the fallen hair are short and small, and the hair bulbs disappear; the symptoms of alopecia are slow, can be in stages, are light and heavy, and can lead to sparse hair on the top of the head or two temples and bright scalp after years; greasy and greasy head or detritus, and thin, soft and yellow hair. At present, no report that the traditional Chinese medicine extract containing thuja and a hair washing and caring product thereof are used for preventing and treating alopecia, especially seborrheic alopecia, is found.
Disclosure of Invention
The first purpose of the invention is to provide a thuja traditional Chinese medicine extract.
The thuja traditional Chinese medicine extract comprises the following raw materials in parts by weight: 10 to 100 parts of thuja, 0.1 to 30 parts of ginger, 0.1 to 30 parts of Chinese honeylocust fruit, 0.1 to 30 parts of tea seed cake, 0.1 to 30 parts of tuber fleeceflower root, 10 to 40 parts of Chinese soapberry fruit, 0.1 to 30 parts of astragalus root, 0.1 to 30 parts of cacumen biotae, 0.1 to 30 parts of belvedere fruit, 0.1 to 30 parts of cortex dictamni, 0.1 to 30 parts of lightyellow sophora root and 0.1 to 30 parts of salvia miltiorrhiza.
Preferably, the components are in parts by weight: 30-100 parts of thuja, 1-5 parts of ginger, 5-10 parts of Chinese honeylocust fruit, 10-20 parts of tea seed cake, 8-12 parts of fleece-flower root, 25-35 parts of Chinese soapberry, 5-10 parts of astragalus root, 13-20 parts of cacumen biotae, 8-12 parts of belvedere fruit, 1-5 parts of cortex dictamni, 8-12 parts of sophora flavescens and 8-12 parts of salvia miltiorrhiza.
More preferably, the components are in parts by weight: 80 parts of thuja, 3 parts of ginger, 8 parts of Chinese honeylocust fruit, 15 parts of dried tea, 8 parts of fleece-flower root, 30 parts of soapberry, 8 parts of astragalus, 15 parts of cacumen biotae, 10 parts of fructus kochiae, 2 parts of cortex dictamni, 10 parts of radix sophorae flavescentis and 10 parts of salvia miltiorrhiza.
In the raw material components, the thuja is selected from root and/or stem and/or leaf of thuja. The rest raw materials are traditional Chinese medicinal materials, and specifically comprise: rhizoma Zingiberis recens, which is rhizome of Zingiber officinale Roscoe of Zingiberaceae, and can be selected from rhizoma Zingiberis recens or Zingiberis rhizoma; fructus Gleditsiae Abnormalis, fruit of Gleditsia sinensis Lam of Leguminosae; tea seed cake, also called cake, oil cake, bran, cake, bran or oil cake, is residue obtained by squeezing oil tea seed of Theaceae family to remove fatty oil; polygoni Multiflori radix, root tuber of Polygonum multiflorum Thunb of Polygonaceae; fructus Sapindi Mukouossi, is seed of Sapindaceae plant Sapindus indica Linn; radix astragali is root of Astragalus membranaceus bge or Astragalus membranaceus bge of Leguminosae; cacumen Platycladi, which is the branches and leaves of Platycladus orientalis of Cupressaceae; kochia scoparia, which is the dried mature fruit of Kochia scoparia belonging to Chenopodiaceae; cortex Dictamni Radicis is root bark of Dictamnus dasycarpus (lour.) Merr or Dictamnus angustifolia of Rutaceae; radix Sophorae Flavescentis, which is dried root of radix Sophorae Flavescentis of Leguminosae; salvia miltiorrhiza is root of Salvia miltiorrhiza belonging to the family Labiatae.
The traditional Chinese medicines are scientifically matched to form a traditional Chinese medicine prescription for nourishing and protecting hair, inhibiting seborrheic dermatitis and alopecia and relieving dandruff and pruritus. The soapberry has the effects of clearing heat, eliminating dampness, removing food retention, killing parasites, inhibiting sebum secretion of head, resisting bacteria, diminishing inflammation, removing dandruff and relieving itching, is the monarch drug with the maximum dosage and comprehensive efficacy; the Chinese medicinal composition has the effects of eliminating dampness and detoxifying due to camellia dregs, cooling blood and dispelling dampness due to the cacumen biotae, clearing heat and promoting diuresis, dispelling wind and relieving itching due to the broom cypress fruits, clearing heat and eliminating dampness, dispelling wind and detoxifying due to the cortex dictamni, clearing heat and eliminating dampness due to the sophora flavescens, and Jiang Sanhan as a component for eliminating dampness and relieving itching, is mainly used for eliminating dampness and relieving itching, is used for enhancing the effect of the soapberry and is a ministerial medicament; the fleece-flower root is an adjuvant drug, and can be used for nourishing scalp, growing hair and fixing hair, reducing the hemolytic action of soapberry and avoiding the stimulation effect of more antibacterial and anti-inflammatory components on scalp; the traditional Chinese medicine composition has the effects of clearing heat, eliminating dampness, relieving itching, sterilizing, nourishing blood, dispelling wind, and remarkably growing hair, controlling oil and removing dandruff when used together. In addition, the raw materials of the invention are also added with arborvitae, arborvitae is mainly used for extracting essential oil, arborvitae essential oil contains terpenoids such as thujone, cedrene and pinene, the aroma is pleasant and refreshing, after terpenoids in arborvitae are absorbed by human body, the respiration and central nervous system are adjusted, the arborvitae essential oil has the functions of relaxing spirit, stabilizing emotion and improving insomnia and dreaminess, the aroma can improve the oxygen content in blood to make people delight, the strong traditional Chinese medicine flavor after the extraction of other traditional Chinese medicine components can be adjusted, the sensory effect of the product after external application is improved, and the arborvitae essential oil has the effects of resisting bacteria, resisting oxidation, expelling worms and resisting inflammation, and the effects of the extract on growing hair, controlling oil and removing dandruff can be enhanced.
The second purpose of the invention is to provide a method for extracting the thuja traditional Chinese medicine extract.
The extraction method comprises the following steps:
1) Putting thuja into a distillation pot, adding water into the distillation pot, soaking for 0.1-5 h, boiling, distilling for 2-8 h, keeping the weight ratio of thuja to water in the distillation pot of 1:6-20, and treating a distillation product by an oil-water separator to obtain thuja essential oil and hydrolat, wherein the thuja essential oil is a component A of a thuja traditional Chinese medicine extract;
2) Filtering the material liquid in the distillation pot, introducing the filtrate into an extraction tank, adding raw material components except for the thuja in the extraction tank, boiling, decocting for 0.5-3 h, filtering, introducing the filtrate into a concentrator, concentrating to 30-40% of the original volume, introducing the hydrolat prepared in the step 1), and concentrating together to obtain clear paste, wherein the clear paste is the component B of the thuja traditional Chinese medicine extract.
Further, in the step 1), the soaking time is 2h, the distilling time is 4h, and the weight ratio of the thuja to the water is 1:8;
further, in the step 2), the decocting time is 2 hours, and the water content of the clear paste is 15% -25%.
Further, in order to collect more extract and save raw material cost, step 1) and step 2) are repeated twice for processing the same raw material.
The extraction method sets different corresponding extraction methods according to different raw materials, wherein the thuja adopts a mode of firstly distilling in water and then separating oil from water to extract essential oil, the other traditional Chinese medicine raw materials are extracted by a traditional water extraction and concentration mode, filtrate obtained after distilling the thuja is introduced during water extraction, and hydrolat obtained by oil-water separation is introduced during concentration, so that water resources are saved, energy consumption is reduced by using waste heat, water soluble components of the thuja during distillation can be recycled, more plant extraction components are obtained, and the health care value of the whole extract is improved.
The third purpose of the invention is to provide the application of the thuja traditional Chinese medicine extract.
In particular to application of the thuja traditional Chinese medicine extract in hair washing and caring products.
More specifically, the hair washing and caring product is shampoo or hair conditioner; preferably, the addition amount of the component A in the hair washing and caring product is 0.1-3 wt%; the addition amount of the component B in the hair washing and caring product is 1wt% -10 wt%.
After the thuja traditional Chinese medicine extract is used as a component of a hair washing and caring product, the obtained shampoo or hair conditioner has pleasant fragrance, does not have strong traditional Chinese medicine smell, controls oil and removes dandruff, grows hair and solidifies hair, and effectively inhibits alopecia, especially alopecia caused by seborrheic dermatitis.
Drawings
FIG. 1 is a flow chart of an extraction method according to an embodiment of the present invention.
Detailed Description
The present invention will now be described with reference to the accompanying drawings, wherein the specific embodiments described herein are merely illustrative and explanatory of the invention and are not restrictive thereof.
Example 1: preparation of arborvitae traditional Chinese medicine extract
The thuja traditional Chinese medicine extract comprises the following raw materials in parts by weight: 80 parts of thuja (branch and leaf), 3 parts of ginger, 8 parts of Chinese honeylocust fruit, 15 parts of tea seed cake, 8 parts of fleece-flower root, 30 parts of soapberry, 8 parts of astragalus root, 15 parts of cacumen biotae, 10 parts of belvedere fruit, 2 parts of cortex dictamni, 10 parts of sophora flavescens and 10 parts of salvia miltiorrhiza.
Referring to fig. 1, the preparation method of the thuja Chinese medicinal extract comprises the following steps: 1) Soaking Thuja orientalis in water in a distillation pot for 2h, boiling, distilling for 4h, keeping the weight ratio of Thuja orientalis to water in the distillation pot of 1:8, and treating the distillation product with an oil-water separator to obtain Thuja orientalis essential oil and hydrolat, wherein the obtained Thuja orientalis essential oil is component A of the traditional Chinese medicine extract of Thuja orientalis; 2) Filtering the material liquid in the distillation pot, introducing the filtrate (decoction) into an extraction tank, adding raw material components except for arborvitae into the extraction tank, boiling, decocting for 2h, filtering, introducing the filtrate (extraction liquid) into a concentrator, concentrating to 30% of the original volume, introducing the hydrolat prepared in the step 1), and concentrating together to obtain clear paste (the weight water content is 20%), wherein the obtained clear paste is component B of the arborvitae traditional Chinese medicine extract; wherein, the step 1) and the step 2) are repeated twice for processing the same part of raw materials.
Example 2: preparation of thuja Chinese medicine extract
The thuja traditional Chinese medicine extract comprises the following raw materials in parts by weight: 30 parts of thuja (branch and leaf), 5 parts of ginger, 5 parts of Chinese honeylocust fruit, 20 parts of tea seed cake, 8 parts of fleece-flower root, 35 parts of soapberry, 5 parts of astragalus root, 20 parts of cacumen biotae, 8 parts of fructus kochiae, 5 parts of cortex dictamni, 8 parts of radix sophorae flavescentis and 12 parts of salvia miltiorrhiza.
Referring to fig. 1, the preparation method of the thuja Chinese medicinal extract comprises the following steps: 1) Soaking Thuja orientalis in water in a distillation pot for 0.1h, boiling, distilling for 8h, keeping the weight ratio of Thuja orientalis to water in the distillation pot of 1:6, and treating the distillation product with an oil-water separator to obtain Thuja orientalis essential oil and hydrolat, wherein the obtained Thuja orientalis essential oil is component A of the Thuja orientalis Chinese medicinal extract; 2) Filtering the material liquid in the distillation pot, introducing the filtrate (decoction) into an extraction tank, adding raw material components except for thuja into the extraction tank, boiling, decocting for 3h, filtering, introducing the filtrate (extraction liquid) into a concentrator, concentrating to 40% of the original volume, introducing the pure water prepared in the step 1), and concentrating together to obtain a clear paste (the weight water content is 15%), wherein the obtained clear paste is the component B of the thuja traditional Chinese medicine extract; wherein, the step 1) and the step 2) are repeated twice for processing the same part of raw materials.
Example 3: preparation of thuja Chinese medicine extract
The thuja traditional Chinese medicine extract comprises the following raw materials in parts by weight: 100 parts of thuja (root), 1 part of dried ginger, 10 parts of Chinese honeylocust fruit, 10 parts of tea seed cake, 12 parts of fleece-flower root, 25 parts of Chinese soapberry, 10 parts of astragalus root, 13 parts of cacumen biotae, 12 parts of belvedere fruit, 1 part of cortex dictamni, 12 parts of sophora flavescens and 8 parts of salvia miltiorrhiza.
Referring to fig. 1, the preparation method of the thuja Chinese medicinal extract comprises the following steps: 1) Soaking thuja in water in a distillation pot for 5h, boiling, distilling for 2h, keeping the weight ratio of thuja to water in the distillation pot to be 1; 2) Filtering the material liquid in the distillation pot, introducing the filtrate (decoction) into an extraction tank, adding raw material components except for the thuja into the extraction tank, boiling, decocting for 0.5h, filtering, introducing the filtrate (extraction liquid) into a concentrator, concentrating to 30% of the original volume, introducing the pure water prepared in the step 1), and concentrating together to obtain a clear paste (the weight water content is 25%), wherein the obtained clear paste is the component B of the thuja traditional Chinese medicine extract.
Example 4: shampoo containing thuja traditional Chinese medicine extract
The shampoo is prepared by compounding the following components in parts by weight according to a conventional preparation process:
30 parts of surfactant, wherein the component ratio is as follows: the weight ratio of sodium laureth sulfate, cocamidopropyl betaine, disodium cocoamphodiacetate, cocamide DEA, potassium cocoyl glycinate is 13.5;
1 part of conditioner, which comprises the following components in parts by weight: the weight ratio of polyquaternium-52, PPG-3 octyl ether, guar gum hydroxypropyl trimethyl ammonium chloride to polyquaternium-10 is 0.3;
2.5 parts of humectant (hyaluronic acid);
0.07 part of emulsifier (laureth-16);
0.05 part of thickening agent (sodium chloride);
0.05 part of preservative (methyl hydroxybenzoate);
0.5 part of pH regulator (citric acid);
45 parts of deionized water;
0.5 part of component A (example 1);
3 parts of component B (example 1).
Example 5: shampoo containing thuja traditional Chinese medicine extract
The shampoo is prepared by compounding the following components in parts by weight according to a conventional preparation process:
25 parts of surfactant, wherein the component ratio is as follows: the weight ratio of sodium laureth sulfate, cocamidopropyl betaine, disodium cocoamphodiacetate, cocamide DEA, potassium cocoyl glycinate is 13.5;
1.1 parts of conditioner, which comprises the following components in parts by weight: the weight ratio of polyquaternium-52, PPG-3 octyl ether, guar gum hydroxypropyl trimethyl ammonium chloride to polyquaternium-10 is (0.2);
2 parts of a humectant (hyaluronic acid);
0.08 portion of emulsifier (laureth-16);
0.1 part of thickener (sodium chloride);
0.05 part of preservative (Kathon preservative);
0.2 part of pH regulator (citric acid);
40 parts of deionized water;
0.1 part of component A (example 2);
2 parts of component B (example 2).
Example 6: shampoo containing thuja traditional Chinese medicine extract
The shampoo is prepared by compounding the following components in parts by weight according to a conventional preparation process:
31 parts of surfactant, wherein the component ratio is as follows: the weight ratio of sodium laureth sulfate, cocamidopropyl betaine, disodium cocoamphodiacetate, cocamide DEA, potassium cocoyl glycinate is 13.5;
0.9 part of conditioner, which comprises the following components in parts by weight: the weight ratio of polyquaternium-52 to PPG-3 octyl ether to guar gum hydroxypropyl trimethyl ammonium chloride to polyquaternium-10 is 0.38;
2.5 parts of a humectant (PEG-7 glycerol cocoate);
0.07 part of emulsifier (laureth-16);
0.08 part of thickening agent (hydroxyethyl cellulose);
0.04 part of preservative, which comprises the following components in parts by weight: the weight ratio of methyl hydroxybenzoate, DMDM hydantoin, and the kathon preservative is 1;
0.1 part of pH regulator (sorbic acid);
30 parts of deionized water;
0.1 part of component A (example 3);
1.5 parts of component B (example 3).
Example 7: hair conditioner containing thuja Chinese medicinal extract
The hair conditioner is prepared by compounding the following components in parts by weight according to a conventional preparation process:
2 parts of natural oil and fat, which comprises the following components in parts by weight: the weight ratio of the camellia seed oil to the horse oil to the beeswax is 1;
3 parts of stearamidopropyl dimethylamine;
4.3 parts of cetearyl alcohol;
0.5 part of lactic acid;
3 parts of panthenol;
0.1 part of disodium ethylene diamine tetraacetate;
0.5 part of preservative (phenoxyethanol);
60 parts of deionized water;
0.1 part of component A (example 1);
5 parts of component B (example 1).
Example 8: hair conditioner containing thuja Chinese medicinal extract
The hair conditioner is prepared by compounding the following components in parts by weight according to a conventional preparation process:
1 part of natural oil and fat, which comprises the following components in parts by weight: the weight ratio of the camellia seed oil to the horse oil to the beeswax is 1;
1 part of stearamidopropyl dimethylamine;
5 parts of cetearyl alcohol;
0.5 part of lactic acid;
5 parts of panthenol;
0.08 part of disodium ethylene diamine tetraacetate;
0.3 part of preservative (benzyl alcohol);
70 parts of deionized water;
0.1 part of component A (example 2);
component B (example 2) 4 parts.
Example 9: hair conditioner containing thuja Chinese medicinal extract
The hair conditioner is prepared by compounding the following components in parts by weight according to a conventional preparation process:
1.5 parts of natural oil and fat, which comprises the following components in parts by weight: the weight ratio of the camellia seed oil to the horse oil to the beeswax is 2;
1 part of stearamidopropyl dimethylamine;
4 parts of cetearyl alcohol;
1 part of lactic acid;
5 parts of panthenol;
0.1 part of disodium ethylene diamine tetraacetate;
0.5 part of preservative (phenoxyethanol);
50 parts of deionized water;
1 part of component A (example 3);
component B (example 3) 3 parts.
Finally, the extract, the shampoo and the hair conditioner are used for tests to verify the hair care effect.
Test example 1: sensory evaluation
Grouping and using methods of shampoo: selecting 60 volunteers, wherein the ages of the volunteers are 18-50 years old, and 30 volunteers are male and female, and the phenomena of alopecia, excessive hair oil, excessive dandruff and scalp pruritus commonly appear in hair; dividing volunteers into 3 groups, each group comprises 20 persons and 10 persons for male and female; after washing hair with about 5-10 mL of shampoo, washing the hair clean with clear water. Each sample was tried for 1 month and the tester scored according to his own feelings.
Conditioner grouping and methods of use: selecting 60 volunteers, wherein the female with the age of 18-40 years generally has the phenomena of alopecia, excessive dandruff and scalp itch; volunteers were divided into 3 groups of 20 persons each; after the hair is washed by the conventional shampoo, the hair is wiped dry, the hair conditioner is uniformly smeared on the hair according to the hair quantity, and the hair is kept for 5 minutes and then is washed clean by clear water. Each sample was tried for 1 month and the tester scored according to his own feelings.
The scoring standard is as follows: the score is 10, the score is 1 is the worst, the score is the best, the higher the score is, the better the effect is, and the test results are shown in the following tables 1 and 2.
TABLE 1 sensory evaluation effect of shampoo containing thuja herb extract
Examples Cleaning effect Anti-dandruff effect Antipruritic effect Oil control effect Hair-strengthening effect
Example 4 9.15 8.80 9.15 7.80 7.50
Example 5 9.00 8.65 9.20 7.50 7.45
Example 6 8.90 8.30 9.30 7.65 7.15
TABLE 2 sensory evaluation of Hair conditioner containing Thuja occidentalis extract
Examples Degree of smoothness Anti-dandruff effect Antipruritic effect Oil control effect Hair-strengthening effect
Example 7 8.65 7.25 7.20 7.95 8.65
Example 8 8.40 7.25 7.30 7.80 8.45
Example 9 8.35 7.00 6.95 7.60 8.50
As can be seen from tables 1 and 2, the shampoo and the hair conditioner containing the thuja traditional Chinese medicine extract have certain effects of removing dandruff, relieving itching, controlling oil and fixing hair, and no side effects such as allergy, scalp discomfort and the like are found in the trial process, so that the shampoo and the hair conditioner have no toxic or side effect and have safety.
Test example 2: clinical trial
1. Clinical data
1.1 general data
The 50 patients were outpatients, 31 men and 19 women; age minimum 20 years, maximum 55 years; the longest course of disease is 5 years, and the shortest course of disease is 1 month; all are patients with seborrheic alopecia.
1.2 diagnostic criteria
The secretion of oil is vigorous, the hair is greasy, or the dandruff is more, the hair is dry, the hair is slowly and diffusely shed, and the scalp is itchy and the hair is sparse.
2. Method of treatment
The extract prepared in the external application embodiment example 1 is used according to the weight ratio of the component A to the component B =1:5, the component B is firstly applied to an alopecia part, then the component A is applied to the alopecia part, and the component A is applied to the alopecia part until the local skin is reddish, 2 times/d, 5-10 mL/time, and 1 month is taken as 1 treatment course. During the treatment period, people should keep working on schedule, avoid using excessive brain and mental stress, and avoid eating greasy and spicy food.
3. Therapeutic results
3.1 therapeutic criteria
The hair loss stops, the hair loss grows out completely, the sebum secretion is recovered to be normal, and the hair loss is cured; the hair loss stops, the hair loss regeneration reaches more than 70 percent, the sebum secretion is obviously reduced, and the effect is obvious; the hair loss stops, the hair loss is regenerated by more than 30 percent, the sebum secretion is reduced, and the hair loss is effective; the hair loss still remains, and the regeneration of the hair loss is less than 30 percent, which is not effective.
3.2 therapeutic results
18 cases of cure (14 men and 4 women); 9 cases of significant effect (7 men and 2 women); 12 cases (10 men and 2 women) were effective; and 11 cases (all women) of the patients with the symptoms. The total effective rate is 78%. The treatment course is 12 treatment courses at the longest and 3 treatment courses at the shortest.
The experiments show that the thuja traditional Chinese medicine extract has the effects of nourishing and protecting hair, controlling oil and removing oil, can be used for treating and improving seborrheic alopecia, and can be diluted and added into hair washing and protecting products such as shampoo, hair conditioner and the like for increasing the effects of the hair washing and protecting products.

Claims (4)

1. The thuja traditional Chinese medicine extract is characterized in that raw materials for preparing the extract comprise the following components in parts by weight: 30-100 parts of thuja, 1-5 parts of ginger, 5-10 parts of Chinese honeylocust fruit, 10-20 parts of tea seed cake, 8-12 parts of fleece-flower root, 25-35 parts of Chinese soapberry, 5-10 parts of astragalus root, 13-20 parts of cacumen biotae, 8-12 parts of belvedere fruit, 1-5 parts of cortex dictamni, 8-12 parts of sophora flavescens and 8-12 parts of salvia miltiorrhiza;
the extraction method of the thuja Chinese medicinal extract comprises the following steps: 1) Putting thuja into a distillation pot, adding water into the distillation pot, soaking for 0.1-5 h, boiling, distilling for 2-8 h, keeping the weight ratio of thuja to water in the distillation pot of 1:6-20, and treating a distillation product by an oil-water separator to obtain thuja essential oil and hydrolat, wherein the thuja essential oil is a component A of a thuja traditional Chinese medicine extract; 2) Filtering the material liquid in the distillation pot, introducing the filtrate into an extraction tank, adding raw material components except for the thuja in the extraction tank, boiling, decocting for 0.5-3 h, filtering, introducing the filtrate into a concentrator, concentrating to 30-40% of the original volume, introducing the hydrolat prepared in the step 1), and concentrating together to obtain clear paste, wherein the clear paste is the component B of the thuja traditional Chinese medicine extract.
2. The thuja Chinese medicinal extract according to claim 1, wherein: in the step 1), the soaking time is 2 hours, the distilling time is 4 hours, and the weight ratio of the thuja to the water is 1:8; in the step 2), the decocting time is 2 hours, and the water content of the clear paste is 15-25%.
3. The thuja Chinese medicinal extract according to claim 1, characterized in that: the step 1) and the step 2) are repeated twice and are used for processing the same part of raw materials.
4. The use of the thuja Chinese medicinal extract as claimed in any one of claims 1 to 3 in hair care products, which is characterized in that: the hair washing and caring product is shampoo or hair conditioner; the addition amount of the component A in the hair washing and caring product is 0.1-3 wt%; the addition amount of the component B in the hair washing and caring product is 1wt% -10 wt%.
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