CN103495102B - Traditional Chinese medicine composition for treating alopecia - Google Patents
Traditional Chinese medicine composition for treating alopecia Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating alopecia. The traditional Chinese medicine composition is prepared from 50-70 parts of drynaria rhizome, 30-50 parts of eclipta, 8-12 parts of medlar, 8-10 parts of poria cocos, 8-10 parts of radix ophiopogonis, 10-15 parts of morinda officinalis, 10-15 parts of radix polygonati officinalis, 8-10 parts of polygonum multiflorum, 8-10 parts of glossy privet fruit, 8-10 parts of red flower, 10-15 parts of Chinese angelica, 8-10 parts of belvedere fruit, 8-12 parts of sealwort, 8-12 parts of epimedium, 5-8 parts of fructus amomi, 8-10 parts of white paeony root, 10-15 parts of suberect spatholobus stem, 8-10 parts of acanthopanax root, 8-10 parts of ginkgo leaf, 25-45 parts of ligusticum wallichii, 10-15 parts of burdock, 6-10 parts of Chinese Pulsatilla Root, 10-15 parts of rhizoma atractylodis, 10-15 parts of semen cuscutae, 8-10 parts of white mulberry root-bark, 8-10 parts of garden balsam stem and the like. The traditional Chinese medicine composition for treating alopecia has the effects of suppressing bacteria, detoxifying and promoting the secretion of saliva, and can be used for treating alopecia.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of Chinese medicine composition of hair growth.
Background technology
Alopecia refers to the phenomenon of alopecia.The hair normally coming off is all the hair in catagen and resting stage, and pathologic alopecia refers to abnormal or excessive the coming off of hair.Cause a lot of because have of alopecia, roughly have three kinds, the factor of the first spirit or health, stress be excessively cause alopecia commonly encountered diseases because of.Psychentonia, melancholy, fear or serious insomnia etc. all can cause nervous dysfunction, and blood capillary continues in contraction state, and hair follicle can not get sufficient blood supply, and scalp is positioned at the top of human body, thereby hair the most easily comes off.If pressure continues, add psychological diathesis a little less than, just easily there is trichokryptomania, food is sent out an addiction, trichotillomania etc.Injury of head, the pathological changes of spinal cord, oblongata, midbrain and brain stem, all can cause alopecia.Nervous and Mental Factors also can seriously affect the growth cycle of hair, for a long time asthenopia, overweight, the neural hypertonicity of stress, irritability or worried emotion, stay up late etc., all can cause the shortening of natural on-off cycles of hair growth cycle, there is alopecia phenomenon, cause male pattern alopecia.
In prior art, the treatment of alopecia is divided into oral medicine, medicine for external use and dietetic therapy.The prescription of the treatment by Chinese herbs primary disease side of enriching blood that nourishes blood; Nourishing the liver and kidney side; Strong liver QI invigorating side; Yin nourishing removing heat from blood side; Liver-smoothing, qi-regulating side.Western medicine alopecia mainly adopts the oral or externals such as finasteride, minoxidil.But the toxic and side effects of Western medicine is often larger, and long-term taking Western medicine can increase the weight of the burden of liver, kidney.
Therefore, still need to find new good effect, approximately thing that toxicity is low carrys out hair growth.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention is according to theory of Chinese medical science, pathogeny for alopecia, take antibacterial, detoxify, promote the production of body fluid, invigorate blood circulation as the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease, provide a kind of and prepared conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the hair growth that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is as follows:
A kind of Chinese medicine composition of hair growth, it is characterized in that being made by the raw material of Chinese medicine medicine of following weight proportioning: Rhizoma Drynariae 50-70, Herba Ecliptae 30-50 part, Fructus Lycii 8-12 part, Poria 8-10 part, Radix Ophiopogonis 8-10 part, Radix Morindae Officinalis 10-15 part, Rhizoma Polygonati Odorati 10-15 part, Radix Polygoni Multiflori Preparata 8-10 part, Fructus Ligustri Lucidi 8-10 part, Flos Carthami 8-10 part, Radix Angelicae Sinensis 10-15 part, Fructus Kochiae 8-10 part, Rhizoma Polygonati 8-12 part, Herba Epimedii 8-12 part, Fructus Amomi 5-8 part, Radix Paeoniae Alba 8-10 part, Caulis Spatholobi 10-15 part, Radix Et Caulis Acanthopanacis Senticosi 8-10 part, Folium Ginkgo 8-10 part, Rhizoma Chuanxiong 25-45 part, Fructus Arctii 10-15 part, Radix Pulsatillae 6-10 part, Rhizoma Atractylodis 10-15 part, Semen Cuscutae 10-15 part, Cortex Mori 8-10 part, Herba speranskiae tuberculatae 8-10 part etc.
Its preparation method is: above-mentioned raw material of Chinese medicine medicated powder is broken into 40-60 object fine powder, adds the alcohol reflux 1-2 hour of 3-5 times of volume, filter, reclaim ethanol, filtrate is condensed into clear paste, and medicinal residues decoct with water again, and the filtrate after filtration is condensed into clear paste; Two parts of clear paste are merged, be condensed into the thick paste that density is 1.25-1.35, be dried to powder; Add starch 20-40 part, microcrystalline Cellulose 10-20 part and lactose 8-15 part, mix, with 60% appropriate amount of ethanol soft material processed, 18-20 mesh sieve is granulated, and 50-60 ℃ dry, 16-18 mesh sieve granulate and get final product.
Chinese medicine composition agent of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected Chinese prescription, and by the adjuvant and the preparation technology that optimize.In Chinese medicine composition of the present invention, clear Rhizoma Drynariae, Herba Ecliptae, Fructus Lycii have the effect of suppressing the hyperactive liver and subsiding YANG, heat extraction improving eyesight, and Poria, Radix Ophiopogonis, Radix Morindae Officinalis, Rhizoma Polygonati Odorati have the effect of blood circulation promoting and blood stasis dispelling, removing heat from blood; Radix Polygoni Multiflori Preparata, Fructus Ligustri Lucidi, Flos Carthami have the effect of promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Radix Angelicae Sinensis, the Fructus Kochiae, Rhizoma Polygonati, Herba Epimedii have enrich blood invigorate blood circulation, the effect of menstruction regulating and pain relieving; The effect of Fructus Amomi, the Radix Paeoniae Alba, Caulis Spatholobi clearing away heat and promoting production of body fluid, hemostasis removing heat from blood; Radix Acanthopanacis Senticosi, Folium Ginkgo, Rhizoma Chuanxiong have the effect of promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Effect source Semen Cuscutae, Cortex Mori, the Herba speranskiae tuberculatae that Fructus Arctii, the Radix Pulsatillae, Rhizoma Atractylodis have clearing away heat and promoting production of body fluid, a removing heat from blood has the effect of inducing diuresis to remove edema, spleen invigorating mind calming.Approximately thing component in the thin compound of Chinese medicine of the present invention is through dialectical compatibility, complements each other using, and has synergism, plays altogether effect antibacterial, that detoxify, promote the production of body fluid, invigorate blood circulation, alopecia reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The prescriptions principle that it follows the traditional Chinese medical science, reaches significant therapeutic effect after oral administration.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
A Chinese medicine composition for hair growth, write out a prescription as follows:
50 grams of Rhizoma Drynariae, 30 grams of Herba Ecliptaes, 8 grams of Fructus Lyciis, 8 grams, Poria, 8 grams of Radix Ophiopogonis, 10 grams of Radix Morindae Officinaliss, 10 grams of Rhizoma Polygonati Odorati, 9 grams of Radix Polygoni Multiflori Preparata, 9 grams of Fructus Ligustri Lucidi, 9 grams, Flos Carthami, 10 grams of Radix Angelicae Sinensis, 9 grams of the Fructus Kochiae, 8 grams of Rhizoma Polygonatis, 8 grams of Herba Epimedii, 5 grams of Fructus Amomis, 8 grams of the Radix Paeoniae Albas, 10 grams of Caulis Spatholobis, 8 grams of Radix Et Caulis Acanthopanacis Senticosis, 8 grams of Folium Ginkgos, 25 grams of Rhizoma Chuanxiongs, 11 grams of Fructus Arctiis, 7 grams of the Radix Pulsatillaes, 10 grams of Rhizoma Atractylodis, 10 grams of Semen Cuscutae, 8 grams of Cortex Mori, 8 grams of Herba speranskiae tuberculataes;
Preparation method is: above-mentioned raw material of Chinese medicine medicated powder is broken into 60 object fine powders, adds the alcohol reflux 2 hours of 5 times of volumes, filter, reclaim ethanol, filtrate is condensed into clear paste, and about slag decocts with water again, and the filtrate after filtration is condensed into clear paste; Two parts of clear paste are merged, be condensed into density and be 1.25 thick paste, be dried to powder; Add 8 grams of 20 grams of starch, 12 grams of microcrystalline Cellulose and lactose, mix, with 60% appropriate amount of ethanol soft material processed, 18 mesh sieves are granulated, and 50 ℃ dry, 16 mesh sieve granulate and get final product.
Embodiment 2
A Chinese medicine composition for hair growth, write out a prescription as follows:
60 grams of Rhizoma Drynariae, 50 grams of Herba Ecliptaes, 12 grams of Fructus Lyciis, 10 grams, Poria, 9 grams of Radix Ophiopogonis, 14 grams of Radix Morindae Officinaliss, 14 grams of Rhizoma Polygonati Odorati, 10 grams of Radix Polygoni Multiflori Preparata, 10 grams of Fructus Ligustri Lucidi, 10 grams, Flos Carthami, 10 grams of Radix Angelicae Sinensis, 10 grams of the Fructus Kochiae, 10 grams of Rhizoma Polygonatis, 10 grams of Herba Epimedii, 8 grams of Fructus Amomis, 10 grams of the Radix Paeoniae Albas, 15 grams of Caulis Spatholobis, 10 grams of Radix Et Caulis Acanthopanacis Senticosis, 10 grams of Folium Ginkgos, 40 grams of Rhizoma Chuanxiongs, 14 grams of Fructus Arctiis, 10 grams of the Radix Pulsatillaes, 14 grams of Rhizoma Atractylodis, 14 grams of Semen Cuscutae, 10 grams of Cortex Mori, 10 grams of Herba speranskiae tuberculataes;
Preparation method is: by receiving crude drug in above-mentioned, be ground into 40 object fine powders, add the alcohol reflux 1 hour of 3 times of volumes, filter, reclaim ethanol, filtrate is condensed into clear paste, and medicinal residues decoct with water again, and the filtrate after filtration is condensed into clear paste; Two parts of clear paste are merged, be condensed into density and be 1.35 thick paste, be dried to powder; Add 35 grams of starch, 13 grams of microcrystalline Cellulose and 11 grams of parts of lactose, mix, with 60% appropriate amount of ethanol soft material processed, 20 mesh sieves are granulated, and 60 ℃ dry, 18 mesh sieve granulate and get final product.
Test example 1
One, test case:
Select 60 routine experimenters, the standard of selection is Western medicine diagnose and differential diagnosis in tcm standard, the age between 18-55, at nearly two weeks any west for oral administration approximately with the hair loss patient that uses other medicine for external use.Adopt randomized, double-blind method, above-mentioned case is divided into treatment group and test group, group result is in Table 1.
Table 1: test case grouped table
| ? | Slightly | Moderate | Severe | Add up to |
| Treatment group | 25 | 8 | 7 | 40 |
| Matched group | 11 | 5 | 4 | 20 |
Two, diagnosis basis:
1, slight: have a small amount of alopecia every day, crown hair is comparatively sparse;
2, moderate: have a large amount of alopecias every day, crown hair is few, and scalp is faintly visible;
3, severe: there is part on the crown without hair.
Three, usage and dosage:
By the method for embodiment 1, prepare Chinese medicine composition of the present invention.Treatment group is taken and in the present invention, is received compositions, every day three times, each 2.5 grams/times, takes continuously two months.The blank placebo of matched group.
Four, criterion of therapeutical effect:
1, cure: alopecia phenomenon alleviates, and crown hair is dense;
2, take a turn for the better: alopecia phenomenon alleviates, and crown hair increases;
3, do not heal: alopecia phenomenon does not alleviate, crown hypotrichosis.
Five, therapeutic effect:
Use the result of the test of the treatment group of Chinese medicine composition of the present invention and the matched group of the blank placebo of use in Table 2.
Table 2: result of the test table
As can be seen from the test results, middle about compositions of the present invention is compared with matched group, and the alopecia of various degree is all had to significant therapeutic effect, has also overcome the untoward reaction of Western medicine simultaneously, has greatly improved patient's compliance.In addition, have no user reflection Chinese medicine composition of the present invention and have any toxic and side effects.
Six, model case:
Case 1:
Patient man, 31 years old, forehead hair was sparse, and scalp is fuel-displaced many, head pruritus, hair is soft, uses Chinese medicine composition of the present invention after 3 months, and forehead grows tiny hair, and the fuel-displaced minimizing of scalp continues to use after 2 months hair blackening chap.
Case 2:
Patient female, 28 years old, alopecia was serious, had the many hairs that come off after getting up on medicated pillow at every turn, had alopecia history 2 years, took Chinese medicine composition of the present invention after 2 months, and alopecia phenomenon reduces, and it is healthy glossy that hair becomes.
Claims (2)
1. a Chinese medicine composition for hair growth, is characterized in that being made by the raw material of Chinese medicine medicine of following weight proportioning:
Rhizoma Drynariae 50-70 part, Herba Ecliptae 30-50 part, Fructus Lycii 8-12 part, Poria 8-10 part, Radix Ophiopogonis 8-10 part, Radix Morindae Officinalis 10-15 part, Rhizoma Polygonati Odorati 10-15 part, Radix Polygoni Multiflori Preparata 8-10 part, Fructus Ligustri Lucidi 8-10 part, Flos Carthami 8-10 part, Radix Angelicae Sinensis 10-15 part, Fructus Kochiae 8-10 part, Rhizoma Polygonati 8-12 part, Herba Epimedii 8-12 part, Fructus Amomi 5-8 part, Radix Paeoniae Alba 8-10 part, Caulis Spatholobi 10-15 part, Radix Et Caulis Acanthopanacis Senticosi 8-10 part, Folium Ginkgo 8-10 part, Rhizoma Chuanxiong 25-45 part, Fructus Arctii 10-15 part, Radix Pulsatillae 6-10 part, Rhizoma Atractylodis 10-15 part, Semen Cuscutae 10-15 part, Cortex Mori 8-10 part, Herba speranskiae tuberculatae 8-10 part,
Its preparation method is: above-mentioned raw material of Chinese medicine medicated powder is broken into 40-60 object fine powder, adds the alcohol reflux 1-2 hour of 3-5 times of volume, filter, reclaim ethanol, filtrate is condensed into clear paste, and medicinal residues decoct with water again, and the filtrate after filtration is condensed into clear paste; Two parts of clear paste are merged, be condensed into the thick paste that density is 1.25-1.35, be dried to powder: add starch 20-40 part, microcrystalline Cellulose 10-20 part and lactose 8-15 part, mix, with 60% appropriate amount of ethanol soft material processed, 18-20 mesh sieve is granulated, 50-60 ℃ dry, 16-18 mesh sieve granulate and get final product.
2. the preparation method of the Chinese medicine composition of a hair growth as claimed in claim 1, the steps include: above-mentioned raw material of Chinese medicine medicated powder to be broken into 40-60 object fine powder, the alcohol reflux 1-2 hour that adds 3-5 times of volume, filter, reclaim ethanol, filtrate is condensed into clear paste, and medicinal residues decoct with water again, and the filtrate after filtration is condensed into clear paste; Two parts of clear paste are merged, be condensed into the thick paste that density is 1.25-1.35, be dried to powder: add starch 20-40 part, microcrystalline Cellulose 10-20 part and lactose 8-15 part, mix, with 60% appropriate amount of ethanol soft material processed, 18-20 mesh sieve is granulated, 50-60 ℃ dry, 16-18 mesh sieve granulate and get final product.
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| CN105031239B (en) * | 2015-07-10 | 2018-06-22 | 北京国济众芳中医药研究所 | There is external medicine composition, preparation of scalp moisturization strengthen the hair and preparation method thereof |
| CN105250949A (en) * | 2015-10-12 | 2016-01-20 | 郑耀玲 | Traditional Chinese medicine composition for preventing hair loss and promoting hair regrowth |
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