CN1136875C - Chuqin Zihou San and its preparing process - Google Patents

Chuqin Zihou San and its preparing process Download PDF

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CN1136875C
CN1136875C CNB011027029A CN01102702A CN1136875C CN 1136875 C CN1136875 C CN 1136875C CN B011027029 A CNB011027029 A CN B011027029A CN 01102702 A CN01102702 A CN 01102702A CN 1136875 C CN1136875 C CN 1136875C
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grams
gram
powder
poultry
radix
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CN1363352A (en
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苏合彬
刘海平
李广升
李松峰
卢卫东
张武信
郏艳玲
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

Abstract

The present invention discloses a power for treating bronchopathy of livestock and poultry and a preparation method thereof. The power for treating bronchopathy of livestock and poultry is prepared from the components by weight: 15 grams of borneol, 15 grams of realgar, 30 grams of scutellaria root, 30 grams of platycodon root, 20 grams of apricot kernel, 30 grams of houttuynia, 15 grams of licorice root, 15 grams of natural indigo, 15 grams of alum, 15 grams of gypsum, 35 grams of isatis root and 35 grams of fructus forsythiae; the components are washed, selected, pulverized, mixed, checked, subpackaged, sealed and warehoused for preservation. The power for treating bronchopathy of livestock and poultry has good curative effect of treating bronchopathy of livestock and poultry.

Description

Powder of treatment poultry bronchitis and laryngotracheitis and preparation method thereof
Technical field
The present invention relates to a kind of powder that is used for the treatment of livestock and birds respiratory disease, especially a kind of powder for the treatment of poultry bronchitis and laryngotracheitis and preparation method thereof.
Background technology
In China that aviculture develops rapidly, respiratory tract disease is modern aviculture, especially the disease that extensively takes place in mechanization, the intensification factory aquaculture, with cough, get rid of hemorrhage, the principal character such as few of laying eggs of head, stream nose, bronchorrhagia, larynx, this disease is having a strong impact on the growth promoter of chicken, and influence egg laying performance, cause very big loss to herding production.Chicken respiratory tract disease causes respiratory mucosa by mycoplasma, mould form body and direct or indirect infection of virus; thickness or hemorrhage exudate in hyperemia, hemorrhagic necrosis, the trachea; trachea, larynx are hemorrhage; occur laryngopharynx swelling and pain clinically, cough, get rid of head, the stream nose, send the sound of " noise made in coughing or vomiting " " noise made in coughing or vomiting "; most of chicken houses; at cold weather; when hen house closes; than being easier to and bringing out respiratory tract disease; disease such as bronchitis, laryngotracheitis; though vaccine prevention is arranged, the vaccine protective rate is not high, makes to cause this disease and caused immeasurable economic loss for China's aquaculture.
Summary of the invention
The purpose of this invention is to provide a kind of a kind of powder for the treatment of poultry bronchitis and laryngotracheitis that can cure livestock and birds respiratory disease, another object of the present invention provides the preparation method of the powder of this treatment poultry bronchitis and laryngotracheitis.
Technical scheme of the present invention is: a kind of powder for the treatment of poultry bronchitis and laryngotracheitis, it is the powder that following materials of weight proportions is made
Borneolum Syntheticum 10-20 gram, Realgar 10-20 gram, Radix Scutellariae 20-40 gram, Radix Platycodonis 20-40 gram, Semen Armeniacae Amarum 10-30 gram, Herba Houttuyniae 20-40 gram, Radix Glycyrrhizae 10-20 gram, Indigo Naturalis 10-20 gram, Alumen 3-7 gram, Gypsum Fibrosum 10-20 gram, Radix Isatidis 20-40 gram, Fructus Forsythiae 20-40 gram.
The weight proportion of each raw material is: Borneolum Syntheticum 15 grams, Realgar 15 grams, Radix Scutellariae 30 grams, Radix Platycodonis 30 grams, Semen Armeniacae Amarum 20 grams, Herba Houttuyniae 30 grams, Radix Glycyrrhizae 15 grams, Indigo Naturalis 15 grams, Alumen 5 grams, Gypsum Fibrosum 15 grams, Radix Isatidis 35 grams, Fructus Forsythiae 35 grams.
The preparation method of the powder of treatment poultry bronchitis and laryngotracheitis:
(1) washing of crude drug, selects, various Chinese crude drugs are washed, select, remove impurity respectively, under natural temperature or 60 ℃ of following intensive dryings.
(2) pulverizing of crude drug: it is standby to cross 60 mesh sieves with 66 type pulverizers pulverizing dried raw material medicine.
(3) mix: each medicine of will filling a prescription dropped in the blender 15 minutes successively by prescription order and ormal weight, in 60-70 ℃ of drying 10 hours, made water content get final product discharging below 7% then.
(4) check: respect under the agent item every regulation according to two appendix of " veterinary drug allusion quotation " nineteen ninety version and test.
(5) packing: the product that is up to the standards is preserved by different size packing, sealing, one-tenth case, warehouse-in, drying, shady and cool place.
The powder that the present invention treats poultry bronchitis and laryngotracheitis be investigate in a large number and experiment basis on, according to motherland's traditional medicine ancient prescription, learn nosetiology and immunology theory in conjunction with modern popular is sick, through the repeated screening test, plus-minus ancestral side forms, and its cube principle is a heat-clearing and toxic substances removing, smooth throat to stop cough, depressed lung-energy dispersing, the tradition traditional Chinese medical science thinks that pyretic toxicity violates lung, and impairment of purifying function of the lung is then given birth to cough with asthma, and the heat body fluid that burns is then nose rhinorrhea of expectorant, the respectful thermogravimetric of lung is laryngopharynx swelling and pain then, imbalance falls in lung qi a surname, and spleen insufficiency then is because other symptomes complice that occurs together after the respiratory tract infection, cause influence and growth, influence is laid eggs, and growth performance descends, and the pharmacology situation of each component is in the prescription:
(1) Borneolum Syntheticum: property suffering, hardship, temperature are gone into the heart, lung, spleen, steal through opening for fragrance, declare interior-heat clearly, and the heat radiation pain relieving is used for laryngopharynx swelling and pain, aphtha, diseases such as skin ulcer phleboedesis poison; (2) Realgar: property is flat, bitter, temperature is gone into the heart, liver, stomach warp, can dampness, detoxify, eliminate the phlegm, swollen clearly pain relieving, the merit that also has wet diabetes involving middle-JIAO to swell and ache and rush down; (3) table black pigment used by women in ancient times to paint their eyebrows: property is salty, bitter cold is gone into the heart, liver, spleen channel, is removing pathogenic heat from blood and toxic substance from the body, the medicine of detumescence pain; (4) Alumen: spleen channel is trembled with fear, is gone in acid, and the effect of antidiarrheal, hemostasis is arranged, and also has drying dampness to eliminate phlegm, the function of sterilization; (5) Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication is with clearing away lung-heat; (6) Fructus Forsythiae: the detumescence of heat-clearing and toxic substances removing eliminating stagnation, the detoxifcation of the clear part of the body cavity above the diaphragm housing the heart and lungs; (7) knot stalk: but heat-clearing and toxic substances removing depressed lung-energy dispersing nourishing the stomach to promote the production of body fluid eliminating phlegm and relieving cough; (8) Radix Isatidis: removing pathogenic heat from blood and toxic substance from the body; (9) Gypsum Fibrosum: have kind clearing heat in QI system and divide excess-heat, the eliminating the pathogens from the lung heat that disappears is let out the gastric heat effect; (10) Semen Armeniacae Amarum: energy relieving cough and asthma, drop-down gas; (11) Herba Houttuyniae: heat-clearing and toxic substances removing, the pain that disappears is swollen etc.; (12) Radix Glycyrrhizae: stomach function regulating coordinating the actions of various ingredients in a prescription, all medicines share common receipts heat-clearing and toxic substances removing, relieving cough and asthma, and the lung moistening and production of body fluid promoting, all medicine compatibilities have curative effect preferably to diseases such as bronchus, larynx tracheas.
Points for attention:
(1) pulverizes: must reach the fineness of regulation, but the Chinese medicine powder color and luster is similar, surely tangible sign will be arranged, avoid mixing medicine.
(2) notice that control is dried wet, to guarantee abundant mixing.
(3) powder moisture necessarily is controlled at below 10%, otherwise long time stored perishable.
(4) powder should be noted the sealing preservation, in case moisture and deteriorate.
The specific embodiment
Below in conjunction with embodiment and test material the present invention is described in further detail.
Embodiment:
Borneolum Syntheticum 15 grams, Realgar 15 grams, Radix Scutellariae 30 grams, Radix Platycodonis 30 grams, Semen Armeniacae Amarum 20 grams, Herba Houttuyniae 30 grams, Radix Glycyrrhizae 15 grams, Indigo Naturalis 15 grams, Alumen 5 grams, Gypsum Fibrosum 15 grams, Radix Isatidis 35 grams, Fructus Forsythiae 35 grams.
Preparation method is as follows:
(1) various Chinese crude drugs is washed, selects, removes impurity respectively, under natural temperature or 60 ℃ of following intensive dryings.
(2) it is standby to cross 60 mesh sieves with 66 type pulverizers pulverizing dried raw material medicine.
(3) each medicine of will filling a prescription dropped in the blender 15 minutes successively by prescription order and ormal weight, in 60-70 ℃ of drying 10 hours, made water content get final product discharging below 7% then.
(4) respecting under the agent item every regulation according to " veterinary drug allusion quotation " nineteen ninety version two appendix tests.
(5) product that is up to the standards is preserved by different size packing, sealing, one-tenth case, warehouse-in, drying, shady and cool place.
Below be some test materials of the present invention's " powder of treatment poultry bronchitis and laryngotracheitis ":
(1) test objective: the clinical drug effect of experiment of checking " powder of treatment poultry bronchitis and laryngotracheitis " powder.
(2) test period: on July 5th, 1997.
(3) test site: Agricultural University Of He'nan's Animal House.
(4) experimental animal: the gushing of 24 ages in week that chicken house is planted by Zhengzhou City Agricultural University Of He'nan to be provided produced layer.
(5) test drug: 1, the powder of treatment poultry bronchitis and laryngotracheitis " in June, 1997 production of powder effluent south agriculture university, recommended dose 1 ‰
2, the artificial challenge uses standard strain:
(1) infectious bronchitis of chicken standard strain
(2) infectious laryngotracheitis of chicken standard strain
(6) test: 1, infect infectious bronchitis and pass through 13347 plumage laying hen groups, 5510 plumage chickling morbidity group prevention effect is observed, and infectious bronchitis of chicken is had remarkable prevention effect, and obvious effective rate is more than 98%.
2, by to treating 15157 plumages with this agent medicine behind artificial challenge's infectious laryngotracheitis standard strain, cure 14959 plumage cure rates 98.7%, wherein 1347 plumages were cured in medication on the 1st, and 9512 plumages were cured in medication on the 2nd, and 41100 plumages were cured in medication on the 3rd.
In order to verify the clinical effectiveness of " powder of treatment poultry bronchitis and laryngotracheitis " powder, we select model case to use powder to carry out clinical trial, treat more than 90 plumage surplus in the of ten thousand altogether, cure rate 93.5%, effective percentage 98.7% now is reported as follows model case:
Test one:
Time: in October, 1997
Poultry is main: Xiping County, Henan Province Er Lang township Yuan Zhuan chicken house, Wang Tiezhuan
The poultry situation: the Luo Man commodity are represented 10,000 of laying hens, 150 ages in days, and the chicken group cough, asthma, sneeze, stream nose occur, shakes the head, noise made in coughing or vomiting goes out mucus or clot, mouth breathing, the region between the heart and the diaphragm of stridulating, laying rate descends, the flat appetite of drinking water reduces, death is arranged, cut open inspection and see that larynx is hemorrhage, hyperemia, tunica mucosa tracheae is hemorrhage, edema.
Plan is examined: infectious laryngotracheitis of chicken
Treatment: with powder by 1% ratio spice every day 1 time, logotype 4 days, symptom obviously alleviates, death stops, chicken group spirit appetite is normal subsequently, the laying rate increase.
Test two:
Time: in December, 1997
Poultry is main: the favorable to the people chicken house of Luohe City
The poultry situation: extra large blue commodity egg, 35 ages in days, 30,000, the chicken group cough, asthma, sneeze, stream nose, trachea occur and rale occurs, a little less than the inner feelings of sick chicken whole body, spirit is stupefied, loss of appetite, feather is fluffy and disorderly, two wings are sagging, normal crowded together.Sickness rate 100%, mortality rate 56%, death is cutd open inspection and is seen that cheese sample tamper, air bag muddiness are arranged in the trachea.
Plan is examined: infectious bronchitis
Treatment: in 1% ratio spice, chicken was grouied busy and inhaled difficult sx the same day with 1 ‰ powders, and death stops, and disease symptom disappears subsequently, and logotype is after 3 days, and it is normal that the chicken group recovers.
Test three:
Time: in January, 1998
Poultry is main: the Tangyin County is breathed out one hundred moral poultry breeding company limited and is planted chicken house for generations
The poultry situation: plant 100,000 of chickens for generations, 90 ages in days sick just suffered from chicken slight respiratory symptom are arranged, and spirit is depressed, there is mucus in oral cavity, nasal cavity, gets rid of head, call hoarse, mouth breathing or cough.Fear of cold squeezes heap, and appetite reduces, and drinking-water increases, and discharges white Calx shape loose stool.To dead, about 6 days, different days was all fallen ill from morbidity, and mortality rate is up to 50%, saw that thick secretions is arranged in the trachea after cuing open inspection, trachea and diaphragm mild hyperaemia or hemorrhage, and renomegaly, tubular ectasia is full of white urate (flower Min kidney) in the tubule
Plan is examined: renal type infectious bronchitis
Treatment: with powder 1% spice, symptom alleviates very soon, and next day, fundamental symptoms disappeared, and is almost recovered in 3rd, and the chicken group progressively transfers normal growth to and grows.
Test four:
Time: in April, 1998
Poultry is main: two Miao Wu villages, Zhu Qu township, Weishi, Henan Province
Poultry situation: partridge chickens, 260 ages in days, 8000 of commodity eggs.
Symptom: get rid of head, cough, heating, the feather principal columns of a hall disorderly, dark slightly, the dyspnea in hat limit wants it serious, laying rate descends, and has loose bowels.
Cut open inspection: die of illness chicken larynx and trachea mucosal swelling expand, and be hemorrhage.
Plan is examined: infectious laryngotracheitis
Treatment: adopt powder 1% ratio spice logotype after 3 days, chicken group rehabilitation, laying rate is progressively recovered.
Test five:
Time: in February, 1998
Poultry is main: pig farm, Miao Li village, Jinshui District Miao Li township, Zhengzhou City, 100 sows.
Situation: have the part pig to breath with cough earlier, the dyspnea symptom appears in several the pigs in back, and it is few to search for food, and hair color is slightly random, tarnish.
Plan is examined: can judge bronchitis according to clinical manifestation
Treatment: with every pig of powder 50 gram consumption spices.The same day, the cough with asthma dyspnea alleviated, and be clearly better next day, was almost recovered after three days, and it is normal that swinery progressively recovers.
By above test material as can be seen, the present invention has following advantage:
1, the effect of treatment poultry bronchopathy is better than similar other medicines.
2, production technology is simple.
3, raw material is easily adopted, and easily preserves, and easily identifies.
4, finished product stability is good, and the several years did not lose efficacy.
5, medication is convenient, has no side effect noresidue.
6, cost is low, is easy to production application, remarkable in economical benefits.

Claims (3)

1, a kind of powder for the treatment of poultry bronchitis and laryngotracheitis is characterized in that, it is the powder that following materials of weight proportions is made:
Borneolum Syntheticum 10-20 gram, Realgar 10-20 gram, Radix Scutellariae 20-40 gram, Radix Platycodonis 20-40 gram, Semen Armeniacae Amarum 10-30 gram, Herba Houttuyniae 20-40 gram, Radix Glycyrrhizae 10-20 gram, Indigo Naturalis 10-20 gram, Alumen 3-7 gram, Gypsum Fibrosum 10-20 gram, Radix Isatidis 20-40 gram, Fructus Forsythiae 20-40 gram.
2, the powder of treatment poultry bronchitis according to claim 1 and laryngotracheitis is characterized in that the weight proportion of each raw material is:
Borneolum Syntheticum 15 grams, Realgar 15 grams, Radix Scutellariae 30 grams, Radix Platycodonis 30 grams, Semen Armeniacae Amarum 20 grams, Herba Houttuyniae 30 grams, Radix Glycyrrhizae 15 grams, Indigo Naturalis 15 grams, Alumen 5 grams, Gypsum Fibrosum 15 grams, Radix Isatidis 35 grams, Fructus Forsythiae 35 grams.
3, the preparation method of the powder of claim 1 described treatment poultry bronchitis and laryngotracheitis is characterized in that:
(1) washing of crude drug, select, various Chinese crude drugs are washed, select, remove impurity respectively, under natural temperature or 60 ℃ of following intensive dryings,
(2) pulverizing of crude drug: it is standby to cross 60 mesh sieves with 66 type pulverizers pulverizing dried raw material medicine,
(3) mix: each medicine of will filling a prescription dropped in the blender 15 minutes successively by prescription order and ormal weight, in 60-70 ℃ of drying 10 hours, made water content get final product discharging below 7% then,
(4) check: respect under the agent item every regulation according to two appendix of " veterinary drug allusion quotation " nineteen ninety version and test,
(5) packing: the product that is up to the standards is preserved by different size packing, sealing, one-tenth case, warehouse-in, drying, shady and cool place.
CNB011027029A 2001-01-08 2001-01-08 Chuqin Zihou San and its preparing process Expired - Fee Related CN1136875C (en)

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CN1136875C true CN1136875C (en) 2004-02-04

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101214295B (en) * 2007-12-27 2010-11-10 付琦 Medicament for treating chicken infectivity laryngotracheitis
CN101711818B (en) * 2008-10-08 2012-01-04 上海朝翔生物技术有限公司 Natural galenical preparation for preventing and treating respiratory diseases of livestock and poultry and preparation method thereof
CN101670061B (en) * 2009-08-26 2011-06-15 郑州后羿制药有限公司 Veterinary drug for treating respiratory tract infection of poultry and preparation method thereof
CN104162074B (en) * 2013-08-30 2017-10-03 河南后羿实业集团有限公司 A kind of veterinary Chinese medicinal composition and preparation method for being used to treat respiratory infectious disease
CN112494593A (en) * 2020-12-31 2021-03-16 广东高山动物药业有限公司 Pure traditional Chinese medicine preparation for resisting respiratory syndrome for poultry

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