CN1136838C - 固体、快速崩解的西替利嗪制剂 - Google Patents

固体、快速崩解的西替利嗪制剂 Download PDF

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Publication number
CN1136838C
CN1136838C CNB998046736A CN99804673A CN1136838C CN 1136838 C CN1136838 C CN 1136838C CN B998046736 A CNB998046736 A CN B998046736A CN 99804673 A CN99804673 A CN 99804673A CN 1136838 C CN1136838 C CN 1136838C
Authority
CN
China
Prior art keywords
effervescent
acid
cetirizine
formulation
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998046736A
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English (en)
Chinese (zh)
Other versions
CN1295464A (zh
Inventor
W
W·特利塔特
�����Ƥ��
M·A·皮斯克尼格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda Pharma GmbH and Co KG
Original Assignee
Asta Medica GmbH
Viatris GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH, Viatris GmbH and Co KG filed Critical Asta Medica GmbH
Publication of CN1295464A publication Critical patent/CN1295464A/zh
Application granted granted Critical
Publication of CN1136838C publication Critical patent/CN1136838C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNB998046736A 1998-03-31 1999-03-20 固体、快速崩解的西替利嗪制剂 Expired - Fee Related CN1136838C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19814256.0 1998-03-31
DE19814256A DE19814256A1 (de) 1998-03-31 1998-03-31 Feste, schnellzerfallende Cetirizin-Formulierungen

Publications (2)

Publication Number Publication Date
CN1295464A CN1295464A (zh) 2001-05-16
CN1136838C true CN1136838C (zh) 2004-02-04

Family

ID=7863014

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998046736A Expired - Fee Related CN1136838C (zh) 1998-03-31 1999-03-20 固体、快速崩解的西替利嗪制剂

Country Status (30)

Country Link
US (1) US6245353B1 (da)
EP (1) EP1067904B1 (da)
JP (1) JP2002509873A (da)
KR (1) KR100653568B1 (da)
CN (1) CN1136838C (da)
AR (1) AR018828A1 (da)
AT (1) ATE209899T1 (da)
AU (1) AU750140B2 (da)
BG (1) BG64741B1 (da)
BR (1) BR9909233A (da)
CA (1) CA2326809C (da)
CY (1) CY1107331T1 (da)
CZ (1) CZ300704B6 (da)
DE (2) DE19814256A1 (da)
DK (1) DK1067904T3 (da)
ES (1) ES2168013T3 (da)
HU (1) HU227477B1 (da)
IL (1) IL138606A (da)
NO (1) NO329071B1 (da)
NZ (1) NZ506988A (da)
PL (1) PL191266B1 (da)
PT (1) PT1067904E (da)
RU (1) RU2216318C2 (da)
SI (1) SI1067904T1 (da)
SK (1) SK284476B6 (da)
TR (1) TR200002809T2 (da)
TW (1) TWI233808B (da)
UA (1) UA57615C2 (da)
WO (1) WO1999049843A1 (da)
ZA (1) ZA200005134B (da)

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KR100863146B1 (ko) * 2000-07-17 2008-10-14 아스텔라스세이야쿠 가부시키가이샤 경구 흡수 개선 의약 조성물
ES2354688T3 (es) * 2002-01-15 2011-03-17 Ucb Farchim S.A. Formulaciones para la administración oral de compuestos activos.
ES2298540T3 (es) * 2002-04-04 2008-05-16 Pfizer Products Inc. Comprimido masticable agradable.
EP3216445A1 (en) 2004-05-28 2017-09-13 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US8216610B2 (en) 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20060198885A1 (en) * 2005-02-22 2006-09-07 Sun Pharmaceutical Industries Ltd. Oral pharmaceutical composition
EP3263117A1 (en) 2005-11-28 2018-01-03 Imaginot Pty Ltd. Oral therapeutic compound delivery system
CN102143737A (zh) * 2008-09-05 2011-08-03 麦克内尔-Ppc股份有限公司 制备西替利嗪片剂的方法
PE20120647A1 (es) * 2009-03-13 2012-05-31 Nucitec Sa De Cv Composiciones y metodos para el tratamiento y prevencion de la enfermedad cardiovascular
EP2571484A2 (en) * 2010-05-18 2013-03-27 Mahmut Bilgic Effervescent formulations
US20140371174A1 (en) 2013-06-12 2014-12-18 The Procter & Gamble Company Effervescent Dosage Form
RU2014149581A (ru) 2012-06-12 2016-07-10 Дзе Проктер Энд Гэмбл Компани Шипучая лекарственная форма
JP5945191B2 (ja) * 2012-08-09 2016-07-05 株式会社ファンケル 口腔内速崩錠
JP6092672B2 (ja) * 2013-03-21 2017-03-08 株式会社ファンケル 口腔内速崩壊性錠剤
KR101591319B1 (ko) * 2013-12-03 2016-02-18 에프엔바이오 주식회사 홍삼 발포정의 제조방법
TWI732337B (zh) * 2014-06-20 2021-07-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
TW201605447A (zh) * 2014-06-20 2016-02-16 美林塔治療學有限公司 處理感染的方法
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
CN106109422A (zh) * 2016-07-28 2016-11-16 北京万全德众医药生物技术有限公司 盐酸左西替利嗪泡腾颗粒及其制备方法
US10624921B2 (en) 2016-11-15 2020-04-21 Berkeley Nox Limited Dietary supplements
JP2018108950A (ja) * 2016-12-28 2018-07-12 沢井製薬株式会社 レボセチリジン塩酸塩含有口腔内崩壊錠
WO2019099003A2 (en) * 2017-11-15 2019-05-23 Berkeley Nox Limited Novel dietary supplements
EP3799864B1 (en) 2019-10-02 2023-03-01 Intas Pharmaceuticals Limited Essentially sodium-free effervescent solid pharmaceutical compositions
US20210236430A1 (en) * 2020-02-03 2021-08-05 Johnson & Johnson Consumer Inc. Single layer chewable tablet comprising cetirizine
CN120437087A (zh) 2024-02-01 2025-08-08 科赴品牌有限责任公司 一种口腔溶解膜制剂、其用途及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155805C (no) * 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
US4678661A (en) * 1983-09-28 1987-07-07 Gerhard Gergely Effervescent composition and method of making same
US4792448A (en) * 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
IL91398A (en) * 1988-08-30 1994-05-30 Pfizer Pharmaceutical delivery device comprising active substance surrounded by asymmetric membrane
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
DE9190107U1 (de) * 1990-08-07 1993-12-16 Pfizer Inc., New York, N.Y. Abgabe-Vorrichtung mit durch Grenzflächen-Polymerisation erhaltenen Membranen
DK0584108T3 (da) * 1991-05-13 2000-10-09 Boots Co Plc Farmaceutisk præparat omfattende ibuprofensalt
GB9119052D0 (en) * 1991-09-06 1991-10-23 Boots Co Plc Pharmaceutical compositions
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
CA2146637C (en) * 1992-10-09 2001-02-13 James Grigg Upson Pharmaceutical compositions and methods for treating cold symptoms
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
FR2698788B1 (fr) * 1992-12-09 1995-03-03 Union Pharma Scient Appl Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
TW401300B (en) * 1992-12-25 2000-08-11 Senju Pharma Co Antiallergic composition for ophthalmic or nasal use
ATE140621T1 (de) * 1993-04-15 1996-08-15 Gergely Gerhard Brausesystem mit einem alkali- und/oder metallempfindlichen, pharmazeutischen wirkstoff, und verfahren zur herstellung
CA2161217A1 (en) * 1993-04-30 1994-11-10 Carmelita Macklin Russell Coated pharmaceutical compositions
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions

Also Published As

Publication number Publication date
EP1067904B1 (de) 2001-12-05
NO20004722L (no) 2000-09-21
PT1067904E (pt) 2002-05-31
BG104843A (en) 2001-07-31
RU2216318C2 (ru) 2003-11-20
DE19814256A1 (de) 1999-10-07
HUP0102676A3 (en) 2002-12-28
CY1107331T1 (el) 2012-12-19
IL138606A (en) 2005-07-25
UA57615C2 (uk) 2003-06-16
JP2002509873A (ja) 2002-04-02
US6245353B1 (en) 2001-06-12
SI1067904T1 (en) 2002-04-30
KR20010034718A (ko) 2001-04-25
BR9909233A (pt) 2000-11-28
IL138606A0 (en) 2001-10-31
AR018828A1 (es) 2001-12-12
HU227477B1 (en) 2011-07-28
SK14312000A3 (sk) 2001-07-10
EP1067904A1 (de) 2001-01-17
CA2326809A1 (en) 1999-10-07
AU750140B2 (en) 2002-07-11
TR200002809T2 (tr) 2000-12-21
NZ506988A (en) 2002-05-31
WO1999049843A1 (de) 1999-10-07
TWI233808B (en) 2005-06-11
CA2326809C (en) 2008-11-18
ZA200005134B (en) 2000-12-21
ES2168013T3 (es) 2002-05-16
NO20004722D0 (no) 2000-09-21
DE59900501D1 (de) 2002-01-17
SK284476B6 (sk) 2005-04-01
DK1067904T3 (da) 2002-04-02
CZ20003481A3 (en) 2001-05-16
AU3925399A (en) 1999-10-18
NO329071B1 (no) 2010-08-16
HK1036217A1 (en) 2001-12-28
ATE209899T1 (de) 2001-12-15
HUP0102676A2 (hu) 2001-11-28
CN1295464A (zh) 2001-05-16
PL191266B1 (pl) 2006-04-28
BG64741B1 (bg) 2006-02-28
CZ300704B6 (cs) 2009-07-22
KR100653568B1 (ko) 2006-12-05
PL343199A1 (en) 2001-07-30

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: MEDA PHARMACEUTICAL CO., LTD.

Free format text: FORMER NAME OR ADDRESS: VIATELESS LIMITED PARTNERSHIP

CP01 Change in the name or title of a patent holder

Address after: German Homburg

Patentee after: MEDA Pharma GmbH & Co. KG

Address before: German Homburg

Patentee before: Viatris GmbH & Co.kg

C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee