CN113425820A - Traditional Chinese medicine formula for treating gastrointestinal diseases and preparation method thereof - Google Patents

Traditional Chinese medicine formula for treating gastrointestinal diseases and preparation method thereof Download PDF

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CN113425820A
CN113425820A CN202110904938.6A CN202110904938A CN113425820A CN 113425820 A CN113425820 A CN 113425820A CN 202110904938 A CN202110904938 A CN 202110904938A CN 113425820 A CN113425820 A CN 113425820A
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范绍剑
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Abstract

The invention provides a traditional Chinese medicine formula for treating gastrointestinal diseases and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. A traditional Chinese medicine formula for treating gastrointestinal diseases comprises: glutinous rice, long-shaped rice, polygonum multiflorum, sand ginger, ovate leaf holly bark, ginseng, codonopsis pilosula, red dates, medlar, pseudo-ginseng, angelica, sugar, jiulong root, lotus seed and black root. The method comprises the following steps: mixing and boiling: adding water into the mixed medicinal materials, heating and decocting for 15-45min, separating medicinal liquid and residue, sun drying the medicinal liquid and the finished product. The inventor finds that water dampness stagnates the spleen, so that the vital essence of the spleen can not promote the normal digestion and operation of the stomach, and the spleen strengthening is essential, so that the symptoms of insomnia and dreaminess, deficiency of both qi and blood, deficiency of vital essence and qi, eating less and no speaking, stomachache, diarrhea and the like of the human body are caused. Therefore, the invention selects the combination of glutinous rice, long-shaped rice, tuber fleeceflower root, sand ginger, ovate leaf holly bark, ginseng, pilose asiabell root, red date, medlar, pseudo-ginseng, angelica, sugar, jiulong root, lotus seed and black root to play the role of treating the intestinal tract disease.

Description

Traditional Chinese medicine formula for treating gastrointestinal diseases and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine formula for treating gastrointestinal diseases and a preparation method thereof.
Background
Functional gastrointestinal disorders (FGIDs) are a class of diseases of the digestive system that have symptoms of the digestive tract and are examined to be either organic or not explained by biochemical structural abnormalities. Patients often have symptoms of poor appetite, early satiety, abdominal pain, nausea, vomiting, abdominal distension, diarrhea, constipation, difficult defecation and the like. The 28 diseases are included according to the current classification, most commonly Functional Dyspepsia (FD), Irritable Bowel Syndrome (IBS), and Functional Constipation (FC).
Functional Dyspepsia (FD) is a clinical syndrome in which clinical symptoms such as epigastric pain or discomfort caused by upper gastrointestinal dysfunction are eliminated, and postprandial epigastric fullness, belching, early satiety, anorexia, nausea, and vomiting are the main symptoms. The disease rate is extremely high, accounting for 20 percent of people and 60 to 70 percent of the outpatient service of the department specialized in digestion. It is very common and frequently indicated. Functional Constipation (FC) is a common disease of the digestive tract, has no obvious organic lesions and is characterized by functional changes, and clinically shows reduced defecation frequency, dry stool and hard defecation. With the change of dietary structure and the influence of various factors such as psychology and society, the FC prevalence rate in China gradually rises, and the life quality of people is seriously influenced. Epidemiological data show that the prevalence rate of chronic constipation in China is as high as 15-20%, wherein the proportion of functional constipation is very large. Irritable Bowel Syndrome (IBS) is a common gastrointestinal non-organic bowel dysfunction disease and has clinical characteristics of chronic recurrent attacks. The prevalence rate in adults is 10% to 22%, and is slightly more frequent in women. It is clinically manifested by abdominal pain, diarrhea, constipation and other digestive system symptoms without organic lesions, and its etiology is gastrointestinal dysfunction. There is currently no effective treatment for this type of disease.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine formula for treating gastrointestinal diseases, and the traditional Chinese medicine composition has the advantages of treating gastrointestinal diseases.
The invention also aims to provide a preparation method of the traditional Chinese medicine formula for treating gastrointestinal diseases, so as to prepare the traditional Chinese medicine formula.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the embodiment of the application provides a traditional Chinese medicine formula for treating gastrointestinal diseases, which comprises the following components in parts by weight: 350 parts of glutinous rice 250-.
On the other hand, the embodiment of the application provides a preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases, which comprises the following steps:
mixing: mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, sugar, radix Baulowniae, semen Nelumbinis and radix Periplocae Radicis;
boiling: adding water into the mixed medicinal materials, heating and decocting for 15-45min, and separating medicinal liquid and residue;
sun-drying: crushing glutinous rice and long-shaped rice into powder, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
and (3) finished product: crushing the medicine residues into 100-200 meshes, and mixing the medicine residues with the medicine powder to obtain a finished product of the traditional Chinese medicine formula.
Sticky rice: sweet in flavor and warm in nature. It enters spleen, stomach and lung meridians. Has effects in invigorating spleen, replenishing qi, invigorating spleen, relieving diarrhea, reducing urination, arresting sweating, and removing toxic materials. Can be used for treating diarrhea due to deficiency-cold of spleen and stomach, cholera, emesis, diabetes, and polyuria.
Indica rice: sweet in flavor and warm in nature. It enters heart, spleen and lung meridians. Has effects in warming middle warmer, invigorating qi, invigorating spleen, and relieving diarrhea. Can be used for treating diarrhea due to deficiency-cold of spleen and stomach.
Polygonum multiflorum: bitter, sweet and astringent taste, slightly warm in nature. It enters liver meridian. Has effects in removing toxic materials, eliminating carbuncle, preventing malaria, and loosening bowel to relieve constipation. Can be used for treating skin ulcer, carbuncle, scrofula, rubella, pruritus, chronic malaria, asthenia, and constipation due to intestinal dryness.
Sand ginger: pungent taste and warm nature. Enters the stomach channel. Has effects of warming spleen and stomach, dispelling cold, promoting appetite, resolving food stagnation, regulating qi-flowing and relieving pain. Is suitable for people with stomach cold, heart and abdomen psychroalgia, borborborygmus diarrhea, and people with anorexia or indigestion.
The cortex Ilicis Rotundae is: bitter taste and cold nature. Has the effects of clearing away heat and toxic materials and promoting diuresis. Can be used for treating common cold, fever, sore throat, damp-heat gastralgia, summer-heat, dampness, diarrhea, jaundice, dysentery, rheumatalgia, eczema, skin ulcer, furuncle, and traumatic injury.
Ginseng: sweet and slightly bitter in flavor and slightly warm in nature. It enters lung meridian. Has effects in invigorating primordial qi, invigorating spleen, benefiting lung, promoting fluid production, tranquilizing mind, and improving intelligence. It is mainly used for treating qi deficiency, hypofunction, spleen qi deficiency, middle-jiao sinking, lung deficiency, asthma, cough, short breath, asthenia, body fluid consumption, thirst, asthenia heat, diabetes, insomnia, amnesia, palpitation, blood deficiency, sallow complexion, sexual impotence, and cold womb.
Codonopsis pilosula: sweet in flavor and neutral in nature. It enters spleen and lung meridians. Has effects in invigorating spleen, benefiting lung, promoting fluid production, and nourishing blood. It is mainly used for treating weakness of spleen and stomach, cough and asthma due to lung deficiency, thirst due to body fluid consumption, blood deficiency and asthenia.
Red dates: sweet in flavor and warm in nature. It enters spleen, stomach and heart meridians. Has effects in invigorating middle warmer, invigorating qi, nourishing blood, and tranquilizing mind. It can be used for treating spleen deficiency, viscera dryness, and insomnia.
Medlar: sweet in flavor and neutral in nature. It enters liver, kidney and lung meridians. Has effects in nourishing liver and kidney, replenishing vital essence, and improving eyesight. Can be used for treating deficiency of liver-yin and kidney-yin, lumbar muscle strain, sexual neurasthenia, chronic prostatitis, and azoospermia, and can be used for treating kidney essence deficiency syndrome, diabetes and hypertension.
Pseudo-ginseng: sweet, slightly bitter and warm in nature. It enters liver meridian. Has effects in removing blood stasis, stopping bleeding, promoting blood circulation, and relieving pain. It is mainly used for various bleeding syndromes, blood stasis swelling and pain, traumatic injuries and the like which belong to blood stasis stagnation.
Chinese angelica: sweet and pungent in flavor and warm in nature; it enters liver, heart and spleen meridians. Has effects in tonifying blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. Can be used for treating blood deficiency, chlorosis, menoxenia, amenorrhea, dysmenorrhea, blood deficiency, blood stagnation, pain due to blood cold, traumatic injury, rheumatalgia, superficial infection, pyocutaneous disease, intestinal dryness, and constipation.
Sugar: white sugar has functions of regulating stomach and relieving urgency, promoting fluid production and moistening dryness, and can be used for treating asthenia, abdominal pain, thirst, and cough due to lung dryness. Maltose has the functions of tonifying deficiency, warming middle-jiao, relieving spasm and pain, moistening lung and arresting cough, and is mainly used for treating deficiency-cold of spleen and stomach, acute abdominal pain, cough due to lung deficiency, dry cough without phlegm and the like.
nine-Dragon root: sweet and bitter taste, warm nature; it enters spleen and liver meridians. Has the effects of dispelling wind-damp and promoting blood and qi circulation. Is mainly used for treating traumatic injury, rheumatic osteodynia and heart and stomach pain.
Lotus seed: sweet and astringent in flavor, neutral in nature, and entering spleen, kidney and heart meridians. Has effects in stopping leukorrhagia, invigorating spleen, relieving diarrhea, invigorating kidney, and nourishing heart. Is mainly used for treating chronic diarrhea due to spleen deficiency, inappetence, kidney-qi deficiency, spermatorrhea due to insecurity of essence, whitish and turbid urine due to imbalance between heart and kidney, nocturnal emission, spleen deficiency, leukorrhagia due to downward flow of water-dampness, imbalance between heart and kidney, vexation and insomnia due to deficiency.
Black bark root: sweet in flavor and neutral in nature. It enters spleen, stomach and kidney meridians. Has effects in invigorating spleen, invigorating stomach, tonifying kidney, and arresting spontaneous emission. It can be used for treating stomach ache due to middle-deficiency, anorexia, and spermatorrhea due to kidney deficiency.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
the inventor finds that water dampness stagnates the spleen, so that the vital essence of the spleen can not promote the normal digestion and operation of the stomach, and the spleen strengthening is essential, so that the symptoms of insomnia and dreaminess, deficiency of both qi and blood, deficiency of vital essence and qi, eating less and no speaking, stomachache, diarrhea and the like of the human body are caused. Therefore, glutinous rice, long-shaped rice, tuber fleeceflower root, sand ginger, ovate leaf holly bark, ginseng, codonopsis pilosula, red date, medlar, pseudo-ginseng, Chinese angelica, sugar, jiulong root, lotus seed and black skin root are selected to be compatible together, so that the effects of tonifying middle-jiao and Qi, enriching blood and activating blood, removing dampness and tonifying spleen, soothing nerves and promoting intelligence and promoting the production of body fluid are achieved, and the aim of tonifying spleen is finally achieved, so that the functions of the gastrointestinal tract are harmonized, and the gastrointestinal diseases are treated. In addition, the traditional Chinese medicine provided by the invention has the advantages of low price, no toxic or side effect, reasonable compatibility and proper formula, and has the advantages of quick response, good curative effect and no damage to human.
The preparation method is simple and convenient, has the advantage of convenient operation, and can quickly and simply prepare the traditional Chinese medicine formula.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The invention provides a traditional Chinese medicine formula for treating gastrointestinal diseases, which comprises the following components in parts by weight: 350 parts of glutinous rice 250-. The inventor finds that water dampness stagnates the spleen, so that the vital essence of the spleen can not promote the normal digestion and operation of the stomach, and the spleen strengthening is essential, so that the symptoms of insomnia and dreaminess, deficiency of both qi and blood, deficiency of vital essence and qi, eating less and no speaking, stomachache, diarrhea and the like of the human body are caused. Therefore, glutinous rice, long-shaped rice, tuber fleeceflower root, sand ginger, ovate leaf holly bark, ginseng, codonopsis pilosula, red date, medlar, pseudo-ginseng, Chinese angelica, sugar, jiulong root, lotus seed and black skin root are selected to be compatible together, so that the effects of tonifying middle-jiao and Qi, enriching blood and activating blood, removing dampness and tonifying spleen, soothing nerves and promoting intelligence and promoting the production of body fluid are achieved, and the aim of tonifying spleen is finally achieved, so that the functions of the gastrointestinal tract are harmonized, and the gastrointestinal diseases are treated. In addition, the traditional Chinese medicine provided by the invention has the advantages of low price, no toxic or side effect, reasonable compatibility and proper formula, and has the advantages of quick response, good curative effect and no damage to human.
In some embodiments of the invention, the traditional Chinese medicine formula comprises the following components in parts by weight: 280 parts of glutinous rice, 280 parts of long-shaped rice, 81 parts of fleece-flower root, 51 parts of sand ginger, 51 parts of ovate leaf holly bark, 51 parts of ginseng, 51 parts of radix codonopsitis, 51 parts of red date, 17 parts of medlar, 17 parts of pseudo-ginseng, 17 parts of angelica, 87 parts of sugar, 177 parts of jiulong root, 17 parts of lotus seed and 17 parts of black-skinned root.
In some embodiments of the invention, the traditional Chinese medicine formula comprises the following components in parts by weight: 300 parts of glutinous rice, 300 parts of long-shaped rice, 84 parts of fleece-flower root, 54 parts of sand ginger, 54 parts of ovate leaf holly bark, 54 parts of ginseng, 54 parts of codonopsis pilosula, 54 parts of red date, 18 parts of medlar, 18 parts of pseudo-ginseng, 18 parts of angelica, 90 parts of sugar, 180 parts of jiulong root, 18 parts of lotus seed and 18 parts of black-skinned root.
In some embodiments of the invention, the traditional Chinese medicine formula comprises the following components in parts by weight: 330 parts of glutinous rice, 330 parts of long-shaped rice, 87 parts of polygonum multiflorum, 57 parts of sand ginger, 57 parts of ovate leaf holly bark, 57 parts of ginseng, 57 parts of codonopsis pilosula, 57 parts of red dates, 19 parts of medlar, 19 parts of pseudo-ginseng, 19 parts of angelica, 93 parts of sugar, 183 parts of jiulong root, 19 parts of lotus seed and 19 parts of black-skinned root.
In some embodiments of the present invention, the sugar is white sugar or maltose. White granulated sugar has the functions of regulating the middle warmer and relieving urgency, promoting the production of body fluid and moistening dryness, and maltose has the functions of tonifying deficiency, warming the middle warmer, relieving urgency and relieving pain, moistening lung and relieving cough, can coordinate the properties of the medicaments, and comprehensively exert the best treatment effect.
The invention also provides a preparation method of the traditional Chinese medicine formula for treating gastrointestinal diseases, which comprises the following steps:
mixing: mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, sugar, radix Baulowniae, semen Nelumbinis and radix Periplocae Radicis;
boiling: adding water into the mixed medicinal materials, heating and decocting for 15-45min, and separating medicinal liquid and residue;
sun-drying: crushing glutinous rice and long-shaped rice into powder, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
and (3) finished product: crushing the medicine residues into 100-200 meshes, and mixing the medicine residues with the medicine powder to obtain a finished product of the traditional Chinese medicine formula.
The medicine is boiled to facilitate the medicine property to permeate into the medicine liquid, and then the medicine liquid is mixed with the glutinous rice powder and the long-shaped rice powder, so that the medicine property can be blended into the glutinous rice powder and the long-shaped rice powder, and the glutinous rice powder and the long-shaped rice powder have mild properties, can play a role in warming middle-jiao and replenishing qi while having synergistic effect with the medicines, and can maintain intestines and stomach; then, the medicine residue powder is mixed with the medicine powder, so that the medicine property can be fully utilized, and the obtained traditional Chinese medicine formula contains dietary fibers of the medicine residues, so that the gastrointestinal peristalsis can be promoted, and the intestines and the stomach can be exercised.
In some embodiments of the present invention, the mixing step is to mix and divide the polygonum multiflorum, the rhizoma zingiberis, the rotundifolia, the ginseng, the codonopsis pilosula, the red dates, the medlar, the panax notoginseng, the angelica, the sugar, the jiulong root, the lotus seeds and the black root into three parts;
decocting the first part of mixed medicine, drying the medicine in the sun and preparing a finished product, and mixing the obtained medicine residue with the medicine powder to obtain a first mixture;
mixing the liquid medicine obtained by decocting the second part of mixed medicines with the first mixture, and then carrying out a medicine drying step to obtain medicine powder of the second part of mixed medicines, crushing medicine residues obtained by mixing the second part of mixed medicines, and mixing the crushed medicine residues with the medicine powder obtained by mixing the second part of mixed medicines to obtain a second mixture;
mixing the liquid medicine obtained by decocting the third part of mixed medicines with the second mixture, and then carrying out a medicine drying step to obtain medicine powder of the third part of mixed medicines, crushing the medicine residues obtained by mixing the third part of mixed medicines, and then mixing the crushed medicine residues with the medicine powder obtained by mixing the third part of mixed medicines to obtain a finished product of the traditional Chinese medicine formula.
The medicines are mixed and divided into three parts for respective treatment, so that the prepared traditional Chinese medicine formula has better efficacy.
In some embodiments of the present invention, the weight ratio of the water in the boiling step to the mixed herbs is 2: 1.
In some embodiments of the present invention, the above boiling step is specifically to separate the liquid medicine and the herb residues after boiling at 90-110 ℃ for 15-45 min.
In some embodiments of the present invention, the above step of drying the drugs comprises crushing the glutinous rice and the indica rice to 100-200 mesh.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
250g of glutinous rice, 250g of long-shaped rice, 75g of polygonum multiflorum, 45g of sand ginger, 45g of ovate leaf holly bark, 45g of ginseng, 45g of codonopsis pilosula, 45g of red dates, 15g of medlar, 15g of pseudo-ginseng, 15g of angelica, 81g of white granulated sugar, 171g of jiulong root, 15g of lotus seed and 15g of black skin root.
Mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, white sugar, radix Bauhihiae Championii, semen Nelumbinis and radix Periplocae Radicis;
adding water at a weight ratio of 2:1 to the mixed medicinal materials, decocting at 90 deg.C for 15min, and separating medicinal liquid and residue;
crushing glutinous rice and long-shaped rice into 100 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
crushing the dregs into 100 meshes, and mixing the crushed dregs with the medicinal powder to obtain a finished product of the traditional Chinese medicine formula.
Example 2
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
280g of glutinous rice, 280g of long-shaped rice, 81g of fleece-flower root, 51g of sand ginger, 51g of ovate leaf holly bark, 51g of ginseng, 51g of codonopsis pilosula, 51g of red date, 17g of medlar, 17g of pseudo-ginseng, 17g of angelica, 87g of white granulated sugar, 177g of jiulong root, 17g of lotus seed and 17g of black skin root.
Mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, white sugar, radix Bauhihiae Championii, semen Nelumbinis and radix Periplocae Radicis;
adding water at a weight ratio of 2:1 to the mixed medicinal materials, decocting at 90 deg.C for 30min, and separating medicinal liquid and residue;
crushing glutinous rice and long-shaped rice into 150 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
crushing the dregs into 150 meshes, and mixing with the medicinal powder to obtain the finished product of the traditional Chinese medicine formula.
Example 3
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
300g of glutinous rice, 300g of long-shaped rice, 84g of polygonum multiflorum, 54g of sand ginger, 54g of ovate leaf holly bark, 54g of ginseng, 54g of codonopsis pilosula, 54g of red dates, 18g of medlar, 18g of pseudo-ginseng, 18g of angelica, 90g of sugar, 180g of jiulong root, 18g of lotus seed and 18g of black skin root.
Mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, white sugar, radix Bauhihiae Championii, semen Nelumbinis and radix Periplocae Radicis;
adding water at a weight ratio of 2:1 to the mixed medicinal materials, decocting at 100 deg.C for 30min, and separating medicinal liquid and residue;
crushing glutinous rice and long-shaped rice into 200 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
crushing the dregs into 200 meshes, and mixing the powder with the dregs to obtain the finished product of the traditional Chinese medicine formula.
Example 4
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
330g of glutinous rice, 330g of long-shaped rice, 87g of polygonum multiflorum, 57g of sand ginger, 57g of ovate leaf holly bark, 57g of ginseng, 57g of codonopsis pilosula, 57g of red dates, 19g of medlar, 19g of pseudo-ginseng, 19g of angelica, 93g of sugar, 183g of jiulong root, 19g of lotus seed and 19g of black skin root.
Mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, white sugar, radix Bauhihiae Championii, semen Nelumbinis and radix Periplocae Radicis;
adding water at a weight ratio of 2:1 to the mixed medicinal materials, decocting at 100 deg.C for 35min, and separating medicinal liquid and residue;
crushing glutinous rice and long-shaped rice into 200 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
crushing the dregs into 200 meshes, and mixing the powder with the dregs to obtain the finished product of the traditional Chinese medicine formula.
Example 5
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
350g of glutinous rice, 350g of long-shaped rice, 93g of fleece-flower root, 63g of sand ginger, 63g of ovate leaf holly bark, 63g of ginseng, 63g of codonopsis pilosula, 63g of red date, 21g of medlar, 21g of pseudo-ginseng, 21g of angelica, 99g of sugar, 189g of Jiulong root, 21g of lotus seed and 21g of black skin root.
Mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, white sugar, radix Bauhihiae Championii, semen Nelumbinis and radix Periplocae Radicis;
adding water at a weight ratio of 2:1 to the mixed medicinal materials, decocting at 110 deg.C for 45min, and separating medicinal liquid and residue;
crushing glutinous rice and long-shaped rice into 200 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
crushing the dregs into 200 meshes, and mixing the powder with the dregs to obtain the finished product of the traditional Chinese medicine formula.
Example 6
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
the mixture ratio and preparation parameters of the embodiment are the same as those of the embodiment 1, except that: the mixed medicines are decocted for three times and are subjected to the steps of decocting, drying the medicines and obtaining the finished product in sequence.
250g of glutinous rice, 250g of long-shaped rice, 75g of polygonum multiflorum, 45g of sand ginger, 45g of ovate leaf holly bark, 45g of ginseng, 45g of codonopsis pilosula, 45g of red dates, 15g of medlar, 15g of pseudo-ginseng, 15g of angelica, 81g of white granulated sugar, 171g of jiulong root, 15g of lotus seed and 15g of black skin root.
Uniformly mixing 3 parts of polygonum multiflorum, rhizoma kaempferiae, ovate leaf holly bark, ginseng, codonopsis pilosula, red date, medlar, pseudo-ginseng, angelica, white granulated sugar, jiulong root, lotus seed and black root;
adding water in a weight ratio of 2:1 into the first part, decocting at 90 deg.C for 15min, and separating medicinal liquid and residue; crushing glutinous rice and long-shaped rice into powder of 100 meshes, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder; crushing the medicine residue into 100 meshes, and mixing the medicine residue with the medicine powder to obtain a first mixture;
adding water into the second part of the mixed medicinal materials in a weight ratio of 2:1, decocting at 90 deg.C for 15min, and separating medicinal liquid and residue; adding the liquid medicine into the first mixture, stirring uniformly, drying in the sun, and mixing with the medicine residues crushed into 100 meshes to obtain a second mixture;
adding water into the third part of the mixed medicinal materials according to the weight ratio of 2:1 to the second part of the mixed medicinal materials, decocting at 90 deg.C for 15min, and separating medicinal liquid and medicinal residue; adding the liquid medicine into the second mixture, stirring uniformly, drying in the sun, and mixing with the medicine residues crushed into 100 meshes to obtain a finished product of the traditional Chinese medicine formula.
Example 7
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
the mixture ratio and preparation parameters of the embodiment are the same as those of the embodiment 2, except that: the mixed medicines are decocted for three times and are subjected to the steps of decocting, drying the medicines and obtaining the finished product in sequence.
Example 8
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
the mixture ratio and preparation parameters of the embodiment are the same as those of the embodiment 3, except that: the mixed medicines are decocted for three times and are subjected to the steps of decocting, drying the medicines and obtaining the finished product in sequence.
Example 9
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
the mixture ratio and preparation parameters of the embodiment are the same as those of the embodiment 4, except that: the mixed medicines are decocted for three times and are subjected to the steps of decocting, drying the medicines and obtaining the finished product in sequence.
Example 10
A preparation method of a traditional Chinese medicine formula for treating gastrointestinal diseases comprises the following steps:
the mixture ratio and preparation parameters of the embodiment are the same as those of the embodiment 5, except that: the mixed medicines are decocted for three times and are subjected to the steps of decocting, drying the medicines and obtaining the finished product in sequence.
Experimental example 1
Animal toxicity test:
100 mice with the age of 7-8 weeks are selected and randomly divided into 10 groups, each group comprises 10 mice, after the mice are raised for one week, no adverse reaction occurs, and the experiment is started.
Each group was fed with the Chinese herbal formulation prepared in examples 1 to 10 2 times a day, and mice were fed with 10g of body weight 0.4ml each time for 2 weeks, and the appearance, behavior, appetite, and excretions of the mice were observed during the feeding, and the mice were dissected after the end of the experiment and observed for heart, liver, spleen, lung, and kidney organs. The results are shown in Table 1.
TABLE 1
Figure BDA0003201277230000131
Figure BDA0003201277230000141
According to table 1, it can be seen that after 2 weeks toxicity test on mice, the mice did not see acute toxicity reaction, and the mice were normal in appearance, behavior, food intake, excretion and viscera, which indicates that the Chinese medicinal formulations prepared in examples 1-10 of the present application are safe.
Experimental example 2
Effect verification:
100 patients with diarrhea, constipation or anorexia are selected, the age is 25-49 years old, 45 men and 55 women are randomly divided into 10 groups, the traditional Chinese medicine formulas prepared in examples 1-10 are sequentially filled into capsules, each capsule contains 228mg of the traditional Chinese medicine formula, the traditional Chinese medicine formula is taken by water every time three times a day and 3-5 capsules each time, 3 days is a treatment course, the patients usually take 1-3 treatment courses, and 3-5 treatment courses are provided for many times, and the treatment conditions are divided into three types of cure, effective and ineffective as shown in table 2.
TABLE 2
Group of Cure/human Effective/human Invalid/human Effective rate%
Group 1 6 3 1 90
2 groups of 7 2 1 90
Group 3 8 2 0 100
4 groups of 7 3 0 100
5 groups of 7 2 1 90
6 groups of 7 2 1 90
7 groups of 8 2 0 100
8 groups of 9 1 0 100
9 groups of 9 1 0 100
10 groups of 8 2 0 100
As can be seen from table 2, the traditional Chinese medicine formula prepared in examples 1 to 10 of the present application has an outstanding therapeutic effect on gastrointestinal diseases and a good therapeutic effect, and analysis of comparative groups 1 to 10 shows that the effect of groups 6 to 10 is significantly superior to that of groups 1 to 5, because the medicines are divided into three parts in examples 6 to 10, and then the three parts are respectively decocted and sequentially subjected to the steps of decocting, drying and finishing, and under the treatment, the medicine properties can be effectively permeated, so that the prepared traditional Chinese medicine formula obtains a better therapeutic effect on gastrointestinal diseases. The best results were obtained for groups 7-10, which demonstrated the best results for the example 7-10.
In conclusion, the inventor finds that water dampness stagnates the spleen, so that essence and qi of the spleen can not promote normal digestion and operation of the stomach, and the spleen strengthening is essential to treat insomnia and dreaminess, deficiency of both qi and blood, deficiency of essence and qi, anorexia and no speaking desire, stomachache, diarrhea and other symptoms of the human body. Therefore, glutinous rice, long-shaped rice, tuber fleeceflower root, sand ginger, ovate leaf holly bark, ginseng, codonopsis pilosula, red date, medlar, pseudo-ginseng, Chinese angelica, sugar, jiulong root, lotus seed and black skin root are selected to be compatible together, so that the effects of tonifying middle-jiao and Qi, enriching blood and activating blood, removing dampness and tonifying spleen, soothing nerves and promoting intelligence and promoting the production of body fluid are achieved, and the aim of tonifying spleen is finally achieved, so that the functions of the gastrointestinal tract are harmonized, and the gastrointestinal diseases are treated. In addition, the traditional Chinese medicine provided by the invention has the advantages of low price, no toxic or side effect, reasonable compatibility and proper formula, and has the advantages of quick response, good curative effect and no damage to human.
The preparation method is simple and convenient, has the advantage of convenient operation, and can quickly and simply prepare the traditional Chinese medicine formula.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The traditional Chinese medicine formula for treating gastrointestinal diseases is characterized by comprising the following components in parts by weight: 350 parts of glutinous rice 250-.
2. The traditional Chinese medicine formula for treating gastrointestinal diseases according to claim 1, which is characterized by comprising the following components in parts by weight: 280 parts of glutinous rice, 280 parts of long-shaped rice, 81 parts of fleece-flower root, 51 parts of sand ginger, 51 parts of ovate leaf holly bark, 51 parts of ginseng, 51 parts of radix codonopsitis, 51 parts of red date, 17 parts of medlar, 17 parts of pseudo-ginseng, 17 parts of angelica, 87 parts of sugar, 177 parts of jiulong root, 17 parts of lotus seed and 17 parts of black-skinned root.
3. The traditional Chinese medicine formula for treating gastrointestinal diseases according to claim 1, which is characterized by comprising the following components in parts by weight: 300 parts of glutinous rice, 300 parts of long-shaped rice, 84 parts of fleece-flower root, 54 parts of sand ginger, 54 parts of ovate leaf holly bark, 54 parts of ginseng, 54 parts of codonopsis pilosula, 54 parts of red date, 18 parts of medlar, 18 parts of pseudo-ginseng, 18 parts of angelica, 90 parts of sugar, 180 parts of jiulong root, 18 parts of lotus seed and 18 parts of black-skinned root.
4. The traditional Chinese medicine formula for treating gastrointestinal diseases according to claim 1, which is characterized by comprising the following components in parts by weight: 330 parts of glutinous rice, 330 parts of long-shaped rice, 87 parts of polygonum multiflorum, 57 parts of sand ginger, 57 parts of ovate leaf holly bark, 57 parts of ginseng, 57 parts of codonopsis pilosula, 57 parts of red dates, 19 parts of medlar, 19 parts of pseudo-ginseng, 19 parts of angelica, 93 parts of sugar, 183 parts of jiulong root, 19 parts of lotus seed and 19 parts of black-skinned root.
5. The traditional Chinese medicine formula for treating gastrointestinal diseases according to any one of claims 1 to 4, wherein the sugar is white sugar or maltose.
6. The method for preparing a Chinese medicinal formulation for treating gastrointestinal diseases according to any one of claims 1 to 4, comprising the steps of:
mixing: mixing Polygoni Multiflori radix, rhizoma Kaempferiae, cortex Ilicis Rotundae, Ginseng radix, radix Codonopsis, fructus Jujubae, fructus Lycii, Notoginseng radix, radix Angelicae sinensis, sugar, radix Baulowniae, semen Nelumbinis and radix Periplocae Radicis;
boiling: adding water into the mixed medicinal materials, heating and decocting for 15-45min, and separating medicinal liquid and residue;
sun-drying: crushing glutinous rice and long-shaped rice into powder, adding the liquid medicine, uniformly stirring, and drying in the sun to obtain medicinal powder;
and (3) finished product: crushing the medicine residues into 100-200 meshes, and mixing the medicine residues with the medicine powder to obtain a finished product of the traditional Chinese medicine formula.
7. The method for preparing a traditional Chinese medicine formula for treating gastrointestinal diseases according to claim 6, wherein the mixing step is to divide fleece-flower root, sand ginger, ovate leaf holly bark, ginseng, radix codonopsitis, red date, medlar, pseudo-ginseng, angelica, sugar, jiulong root, lotus seed and black root into three parts after mixing;
decocting the first part of mixed medicine, drying the medicine in the sun and preparing a finished product, and mixing the obtained medicine residue with the medicine powder to obtain a first mixture;
mixing the liquid medicine obtained by decocting the second part of mixed medicines with the first mixture, and then carrying out a medicine drying step to obtain medicine powder of the second part of mixed medicines, crushing medicine residues obtained by mixing the second part of mixed medicines, and mixing the crushed medicine residues with the medicine powder obtained by mixing the second part of mixed medicines to obtain a second mixture;
mixing the liquid medicine obtained by decocting the third part of mixed medicines with the second mixture, and then carrying out a medicine drying step to obtain medicine powder of the third part of mixed medicines, crushing the medicine residues obtained by mixing the third part of mixed medicines, and then mixing the crushed medicine residues with the medicine powder obtained by mixing the third part of mixed medicines to obtain a finished product of the traditional Chinese medicine formula.
8. The preparation method of the traditional Chinese medicine formula for treating gastrointestinal diseases according to claim 6, wherein the weight ratio of water in the boiling step to the mixed medicinal materials is 2: 1.
9. The preparation method of the traditional Chinese medicine formula for treating gastrointestinal diseases as claimed in claim 6, wherein the decocting step is to separate the liquid medicine and the dregs after decocting at 90-110 ℃ for 15-45 min.
10. The method for preparing a Chinese medicinal formulation for treating gastrointestinal diseases as claimed in claim 6, wherein the step of sun-drying Oryza Glutinosa and semen oryzae is carried out to 100-200 mesh.
CN202110904938.6A 2021-08-07 2021-08-07 Traditional Chinese medicine formula for treating gastrointestinal diseases and preparation method thereof Pending CN113425820A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105433077A (en) * 2014-09-29 2016-03-30 张秋云 Pilose asiabell root-lotus seed-fructus jujubae congee for treating irritable bowel syndrome

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105433077A (en) * 2014-09-29 2016-03-30 张秋云 Pilose asiabell root-lotus seed-fructus jujubae congee for treating irritable bowel syndrome

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Title
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