CN105250749A - Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof - Google Patents

Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof Download PDF

Info

Publication number
CN105250749A
CN105250749A CN201510648318.5A CN201510648318A CN105250749A CN 105250749 A CN105250749 A CN 105250749A CN 201510648318 A CN201510648318 A CN 201510648318A CN 105250749 A CN105250749 A CN 105250749A
Authority
CN
China
Prior art keywords
parts
herba
chinese medicine
obtains
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510648318.5A
Other languages
Chinese (zh)
Inventor
徐兴鲁
厉秀玲
Original Assignee
徐兴鲁
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 徐兴鲁 filed Critical 徐兴鲁
Priority to CN201510648318.5A priority Critical patent/CN105250749A/en
Publication of CN105250749A publication Critical patent/CN105250749A/en
Pending legal-status Critical Current

Links

Abstract

The invention provides traditional Chinese medicine for treating a thyroid adenoma and a preparation method thereof. Raw herbal materials of the traditional Chinese medicine comprise tangut dragonhead, radix thalictri simplicis, elsholtzia bodinieri vaniot, ecristate corydalis herbs, hoya carnosa, feldspar, flatstiped corydalis herbs, giant soft-shelled turtle shells, Chinese forgetmenot herbs, trifolium lupinaster, jasminum grandiflorum, nanocnide lobata, fourleaf peperomia herbs and rough melic herbs. The traditional Chinese medicine has the exact curative effect on the thyroid adenoma and is free of toxic and side effects.

Description

A kind of Chinese medicine for the treatment of thyroid adenoma and preparation method thereof
Technical field
The present invention relates to the medicinal preparation containing deriving from plant, animal or mineral component, particularly relating to a kind of Chinese medicine for the treatment of thyroid adenoma and preparation method thereof.
Background technology
Thyroid adenoma is the benign tumor originating from thyroid follicular cells, is the modal benign tumor of thyroid.Be apt to occur in the active stage of thyroid function.Clinical point of filter blocking and adenoma papilliforum two kinds.Patient mostly is women, and the age is everlasting less than 40 years old, is generally the Solitary nodules in thyroid body.The course of disease is slow, most several months to the several years even the time longer, patient finds because of slightly uncomfortable or is found cervical region without any symptom to swell thing.Majority is single-shot, circular or oval, smooth surface, clear border, the tough reality of quality, with surrounding tissue without adhesion, without tenderness, can move up and down with swallowing.
Western medical treatment mainly based on operation and thyroxine therapy, but respectively has pluses and minuses.Have after total thyroidectomy up to 5% recurrence may, need postoperatively for a long time to take thyroxine even throughout one's life and recur to prevent it.And the full lobectomy of thyroid can cause the postoperative hypothyroidism of patient relatively thoroughly, the insufficiency of function also needing patient to take thyroxin tablet throughout one's life lowly to cause to make up hormonal readiness.And thyroxine therapy easily produces the untoward reaction such as nervous, irritated, arrhythmia, unstable blood pressure are fixed.
Thyroid adenoma belongs to Chinese medicine " goiter " category.Modern times, doctor thought that the pathogenic factor of primary disease was mainly feelings will internal injury, diet water and soil is inappropriate relevant with institutional factor.Long-term depression angry or strongly fragrant worry of being worried, i.e. feelings will internal injury, can make depression and stagnation of QI, irritability is lost and is reached in bar.And body fluid normally follow row and defeated cloth all need the operation of gas to promote, depression and stagnation of QI, then body fluid is easy to be condensed into expectorant.Stagnation of QI expectorant coagulates, and stops up knot throat, then forms goiter.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of Chinese medicine for the treatment of thyroid adenoma and preparation method thereof, and Chinese medicine of the present invention has definite curative effect to thyroid adenoma, and toxic and side effects is little.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine for the treatment of thyroid adenoma, its raw medicinal material comprises: Herba Dracocephali tangutici, Herba Thalictri Ramosi, Herba Pteridis Multifidae, Herba Corydalis tailensis, Caulis seu folium hoyaecarnosae, Anhydrite, flatstiped corydalis herb, Carapax pelochelydis, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis), Herba Trifolii lupinasteris, Jasminum polyanthum Franch., snow medicine, Herba Seu Radix Peperomiae Tetraphyllae and Melica scabrosa Trin..
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Herba Dracocephali tangutici 10 ~ 20 parts, Herba Thalictri Ramosi 20 ~ 30 parts, Herba Pteridis Multifidae 10 ~ 20 parts, Herba Corydalis tailensis 10 ~ 20 parts, Caulis seu folium hoyaecarnosae 5 ~ 15 parts, Anhydrite 10 ~ 20 parts, flatstiped corydalis herb 20 ~ 30 parts, Carapax pelochelydis 20 ~ 30 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 15 ~ 25 parts, Herba Trifolii lupinasteris 20 ~ 30 parts, Jasminum polyanthum Franch. 10 ~ 20 parts, snow medicine 10 ~ 20 parts, Herba Seu Radix Peperomiae Tetraphyllae 8 ~ 18 parts and Melica scabrosa Trin. 5 ~ 15 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Herba Dracocephali tangutici 10 ~ 15 parts, Herba Thalictri Ramosi 20 ~ 25 parts, Herba Pteridis Multifidae 15 ~ 20 parts, Herba Corydalis tailensis 12 ~ 17 parts, Caulis seu folium hoyaecarnosae 8 ~ 13 parts, Anhydrite 13 ~ 18 parts, flatstiped corydalis herb 22 ~ 27 parts, Carapax pelochelydis 20 ~ 25 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 18 ~ 23 parts, Herba Trifolii lupinasteris 25 ~ 30 parts, Jasminum polyanthum Franch. 15 ~ 20 parts, snow medicine 13 ~ 18 parts, Herba Seu Radix Peperomiae Tetraphyllae 10 ~ 15 parts and Melica scabrosa Trin. 7 ~ 12 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Dracocephali tangutici 14 parts, Herba Thalictri Ramosi 22 parts, Herba Pteridis Multifidae 18 parts, Herba Corydalis tailensis 13 parts, Caulis seu folium hoyaecarnosae 12 parts, Anhydrite 15 parts, flatstiped corydalis herb 26 parts, Carapax pelochelydis 20 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 22 parts, Herba Trifolii lupinasteris 26 parts, Jasminum polyanthum Franch. 20 parts, snow medicine 14 parts, Herba Seu Radix Peperomiae Tetraphyllae 15 parts and Melica scabrosa Trin. 8 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Dracocephali tangutici 12 parts, Herba Thalictri Ramosi 25 parts, Herba Pteridis Multifidae 16 parts, Herba Corydalis tailensis 15 parts, Caulis seu folium hoyaecarnosae 10 parts, Anhydrite 18 parts, flatstiped corydalis herb 24 parts, Carapax pelochelydis 24 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 20 parts, Herba Trifolii lupinasteris 28 parts, Jasminum polyanthum Franch. 16 parts, snow medicine 15 parts, Herba Seu Radix Peperomiae Tetraphyllae 12 parts and Melica scabrosa Trin. 10 parts.
Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.
Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:
The first step, is mixed in proportion described raw medicinal material, is ground into powder;
Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;
5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.
Beneficial effect of the present invention: Chinese medicine of the present invention has definite curative effect to thyroid adenoma, has no side effect.
Detailed description of the invention
The invention provides a kind of Chinese medicine for the treatment of thyroid adenoma, its raw medicinal material comprises: Herba Dracocephali tangutici, Herba Thalictri Ramosi, Herba Pteridis Multifidae, Herba Corydalis tailensis, Caulis seu folium hoyaecarnosae, Anhydrite, flatstiped corydalis herb, Carapax pelochelydis, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis), Herba Trifolii lupinasteris, Jasminum polyanthum Franch., snow medicine, Herba Seu Radix Peperomiae Tetraphyllae and Melica scabrosa Trin..
In described Chinese medicine, the pharmacology of each raw medicinal material is as follows:
Herba Dracocephali tangutici: [source] medical material Ji Yuan: be the whole herb with root of labiate tangut dragonhead.[nature and flavor] acrid in the mouth; Bitter; Cold in nature.[function cures mainly] clearing away heat-damp and promoting diuresis; Preventing phlegm from forming and stopping coughing.Main icterohepatitis; Gastritis; Gastric ulcer; Tracheitis.[extracts] " China's book on Chinese herbal medicine "
Herba Thalictri Ramosi: [another name] RadixThalictrisimplicis.[source] medical material Ji Yuan: be the herb of ranunculaceae plant racemosus Thalictrum aquilegifolium L. var. sibiricum Regel.[nature and flavor] bitter in the mouth; Cold in nature.[return through] returns liver; Large intestine channel.[function cures mainly] heat clearing and damp drying; Removing toxic substances.Cure mainly dysentery; Jaundice; Conjunctival congestion; Carbuncle furuncle.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "
Herba Pteridis Multifidae: [source] medical material Ji Yuan: be the herb of labiate East Perillae and different leaf Herba Moslae.[nature and flavor] acrid in the mouth; Property is put down.[function cures mainly] disperses exopathogen; Regulating qi-flowing for harmonizing stomach.Main flu; Pharyngitis; Conjunctival congestion and swelling pain; Stomatitis; Toothache; Hepatitis; Dyspepsia.[extracts] " China's book on Chinese herbal medicine "
Herba Corydalis tailensis: [another name] Radix seu Caulis Parthenocissi tricuspidatae Seedling, golden hook Viola arcuata, water gold hook comply with one's wishes, Gelsemium elegans Benth., RadixThalictrisimplicis, Dali Herba corydalis edulis, water comply with one's wishes.[source] medical material Ji Yuan: be the herb of bloodroot Herba Corydalis tailensis.[nature and flavor] are bitter; Be slightly cold.[return through] liver; Lung meridian.[function cures mainly] dispels the wind; Heat clearing away; Pain relieving; Liver heat removing and eyesight improving.Main anemopyretic cold; Cough due to lung-heat; Pulmonary tuberculosis hemoptysis; Hepatitis; Fengshi Guanjie bones and muscles pain; Toothache; Conjunctival congestion; Cataracta.[extracts] " China's book on Chinese herbal medicine "
Caulis seu folium hoyaecarnosae: [another name] ferrum adds cup, golden snowball, cow tongue Huang, cliff prunus mume (sieb.) sieb.et zucc., spun gold leaf, silk ball leaf, great Shi celestial being are chosen, climb rock beam, straw sandals plate, beautiful folded prunus mume (sieb.) sieb.et zucc., beautiful butterfly prunus mume (sieb.) sieb.et zucc., wall prunus mume (sieb.) sieb.et zucc., Gu Mei, silk ball dragon, thick leaf rattan, reach bucket rattan, snow prunus mume (sieb.) sieb.et zucc., pneumonia are careless.[source] medical material Ji Yuan: be rattan or the leaf of dicotyledon medicine asclepiadaceae plant Caulis seu folium hoyaecarnosae.[nature and flavor] bitter in the mouth; Cold in nature; Mild toxicity.[return through] lung; The heart; Liver Channel.[function cures mainly] removing heat-phlegm; Reducing swelling and alleviating pain; To stimulate the menstrual flow stimulating milk secretion.Main epidemic encephalitis type B; Cough due to lung-heat; Carbuncle; Breast woman milk is few; Arthralgia; Orchitis; Otitis media; Mastitis; Scrofula; Puerpera's hypogalactia; Breast network is obstructed.[extracts] " China's book on Chinese herbal medicine "
Anhydrite: [another name] ashlar, straight stone, native stone, anhydrite.[source] medical material Ji Yuan: the Ore of Sulfates mineral anhydrite.[nature and flavor] are bitter; Pungent; Cold; Nontoxic.[return through] lung; Liver; Bladder; Stomach warp.[function cures mainly] liver heat removing and eyesight improving; Promoting the circulation of QI to induce diuresis.Main fever of the body excessive thirst; Cataract; Dysuria.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "
Flatstiped corydalis herb: [another name] winter department.[source] medical material Ji Yuan: be the whole herb with root of the flat handle Herba corydalis racemosae of bloodroot.[nature and flavor] are bitter; Cold.[function cures mainly] heat-clearing and toxic substances removing; Pain relieving.Main flow sense; Epidemic febrile disease is generated heat; Gastritis; Peptic Ulcers; Dysentery; Sciatica; Furuncle swells and ache.[extracts] " China's book on Chinese herbal medicine "
Carapax pelochelydis: [another name] green soft-shelled turtle, favus-infected head soft-shelled turtle.[source] medical material Ji Yuan: be the carapace of Trionychidae animal soft-shelled turtle.[nature and flavor] sweet in the mouth; Salty; Property is put down.[return through] liver; Kidney channel.[function cures mainly] nourishing YIN for suppressing the hyperactive YANG; Hard masses softening and resolving; Removing toxic substances parasite killing.Having a dizzy spell of main hyperactivity of YANG due to deficiency of YIN; Waist knee joint flaccidity is soft; Scrofula; Dislike macromolecule; Hemorrhoid complicated by anal fistula; Stubborn dermatitis.[extracts] " China's book on Chinese herbal medicine "
Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis): [another name] tackles all problems at once, blue Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis), blue cloth skirt, Herba Trigonotidis peduncularis, cow tongue headdress flower, Canis familiaris L. tongue flower, Herba Poae Sphondylodis, seven-star arrow, Mao Maocai, large fertile root, L otus cotyledon, the LVHUA heart, LVHUA leaf, Radix Wahlenbergiae Marginatae, the blue flower of bullshit, fore-tellings of bullshit sieve, Rhizoma seu Herba Elatostematis stewardii, little green company are careless.[source] medical material Ji Yuan: be the aerial parts of comfrey Herba Carpesii Cernui.[nature and flavor] are bitter; Cool.[return through] lung; Liver; Kidney channel.[function cures mainly] removing heat from the lung and dissipating phlegm; Dissipating blood stasis stops blooding; Clearing away heat-damp and promoting diuresis.Main cough; Spit blood; Hepatitis; Dysentery; Dysurea; Leucorrhea; Scrofula; Knife injury; Fracture.[extracts] " China's book on Chinese herbal medicine "
Herba Trifolii lupinasteris: [another name] wild clover, bean ginseng, also fireball, Ye Huo bush clover.[source] medical material Ji Yuan: be the herb of leguminous plant Herba Trifolii lupinasteris.[nature and flavor] bitter in the mouth; Property is put down.[return through] lung; The heart; Liver Channel.[function cures mainly] cough-relieving; Analgesia; Eliminating stagnation.Main cough with asthma; Lymphoid tuberculosis; Hemorrhoid; Tinea corporis.[extracts] " China's book on Chinese herbal medicine "
Jasminum polyanthum Franch.: [another name] Herba jasmini polyanthi, chicken feet flower, Flos jasmini.[source] medical material Ji Yuan: for Oleaceae plants spends more Herb and the flower of jasmine.[nature and flavor] are bitter; Micro-pungent; Cool in nature.[function cures mainly] circulation of qi promoting; Invigorate blood circulation; Pain relieving; Heat clearing away eliminating stagnation.Main breast side of body abdominal distention; Stasis dysmenorrhea; Menoxenia; Painful and swollen testis; Lymphoid tuberculosis.[extracts] " China's book on Chinese herbal medicine "
Snow medicine: [another name] ripple silk grass, little Herba Polygoni Runcinati, hair leaf Rhizoma Belamcandae, red Herba Ceratophylli Demeersi, everywhere red, Radix seu Folium Gaultheriae Forrestii, Herba Glechomae Boehmeria.[source] medical material Ji Yuan: be the herb of contrayerva Herba Nanocnides pilosae.[nature and flavor] are bitter; Cool in nature.[function cures mainly] heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds; Hemostasis.Main cough due to lung-heat; Scrofula; Spitting of blood; Burn and scald; Carbuncle; Traumatic injury; Venom; Traumatic hemorrhage.[extracts] " China's book on Chinese herbal medicine "
Herba Seu Radix Peperomiae Tetraphyllae; [another name] Semen Sojae Preparatum Herba Pyrolae, rock muscle grass, Semen Sojae Preparatum Viola arcuata, Semen Benincasae deer rank, Semen Benincasae Herba Asari, Herba Sedi tetractini, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae), Moghania fluminalis(C. B. Clarke) Li lobe, Semen Sojae Preparatum grass, roundleaf Semen Benincasae dish, stone is revived after death, rock is spent, stone on watt slurry, Herba Anotis ingratae, 3 years grass.[source] medical material Ji Yuan: be the herb of Piperaceae plant Herba Seu Radix Peperomiae Tetraphyllae or hair YEDOU lobe.[nature and flavor] are pungent; Bitter; Tepor.[return through] lung; Liver; Spleen channel.[function cures mainly] relaxing muscles and tendons to promote blood circulation; Expelling wind and removing dampness; Preventing phlegm from forming and stopping coughing.Main bones and muscles pain due to rheumatism; Traumatic injury; Furuncle toxic swelling; Pharyngolaryngitis; Stomatitis; Dysentery; Watery diarrhea; Dyspepsia does not disappear; Infantile malnutrition; Epersalgia cough; Asthma; Pertussis.[extracts] " China's book on Chinese herbal medicine "
Melica scabrosa Trin.: [another name] Herba Melicae Scabrosae, fertile Herba Setariae Plicatae, rifle grass.[source] medical material Ji Yuan: be the herb of grass Herba rutae.[nature and flavor] are sweet; Cool.[function cures mainly] inducing diuresis for treating stranguria syndrome; Heat clearing away jaundice eliminating.Main urinary tract infection; Oedema due to nephritis; Cold, fever; Icterohepatitis; Diabetes.[extracts] " China's book on Chinese herbal medicine "
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Herba Dracocephali tangutici 10 ~ 20 parts, Herba Thalictri Ramosi 20 ~ 30 parts, Herba Pteridis Multifidae 10 ~ 20 parts, Herba Corydalis tailensis 10 ~ 20 parts, Caulis seu folium hoyaecarnosae 5 ~ 15 parts, Anhydrite 10 ~ 20 parts, flatstiped corydalis herb 20 ~ 30 parts, Carapax pelochelydis 20 ~ 30 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 15 ~ 25 parts, Herba Trifolii lupinasteris 20 ~ 30 parts, Jasminum polyanthum Franch. 10 ~ 20 parts, snow medicine 10 ~ 20 parts, Herba Seu Radix Peperomiae Tetraphyllae 8 ~ 18 parts and Melica scabrosa Trin. 5 ~ 15 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Herba Dracocephali tangutici 10 ~ 15 parts, Herba Thalictri Ramosi 20 ~ 25 parts, Herba Pteridis Multifidae 15 ~ 20 parts, Herba Corydalis tailensis 12 ~ 17 parts, Caulis seu folium hoyaecarnosae 8 ~ 13 parts, Anhydrite 13 ~ 18 parts, flatstiped corydalis herb 22 ~ 27 parts, Carapax pelochelydis 20 ~ 25 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 18 ~ 23 parts, Herba Trifolii lupinasteris 25 ~ 30 parts, Jasminum polyanthum Franch. 15 ~ 20 parts, snow medicine 13 ~ 18 parts, Herba Seu Radix Peperomiae Tetraphyllae 10 ~ 15 parts and Melica scabrosa Trin. 7 ~ 12 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Dracocephali tangutici 14 parts, Herba Thalictri Ramosi 22 parts, Herba Pteridis Multifidae 18 parts, Herba Corydalis tailensis 13 parts, Caulis seu folium hoyaecarnosae 12 parts, Anhydrite 15 parts, flatstiped corydalis herb 26 parts, Carapax pelochelydis 20 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 22 parts, Herba Trifolii lupinasteris 26 parts, Jasminum polyanthum Franch. 20 parts, snow medicine 14 parts, Herba Seu Radix Peperomiae Tetraphyllae 15 parts and Melica scabrosa Trin. 8 parts.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Dracocephali tangutici 12 parts, Herba Thalictri Ramosi 25 parts, Herba Pteridis Multifidae 16 parts, Herba Corydalis tailensis 15 parts, Caulis seu folium hoyaecarnosae 10 parts, Anhydrite 18 parts, flatstiped corydalis herb 24 parts, Carapax pelochelydis 24 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 20 parts, Herba Trifolii lupinasteris 28 parts, Jasminum polyanthum Franch. 16 parts, snow medicine 15 parts, Herba Seu Radix Peperomiae Tetraphyllae 12 parts and Melica scabrosa Trin. 10 parts.
Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.
Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:
The first step, is mixed in proportion described raw medicinal material, is ground into powder;
Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;
5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.
Below adopt embodiment to describe embodiments of the present invention in detail, fully understand how application technology means solve technical problem in the present invention whereby, reach technique effect and implement according to this.
Embodiment 1: capsule
Get Herba Dracocephali tangutici 120g, Herba Thalictri Ramosi 250g, Herba Pteridis Multifidae 160g, Herba Corydalis tailensis 150g, Caulis seu folium hoyaecarnosae 100g, Anhydrite 180g, flatstiped corydalis herb 240g, Carapax pelochelydis 240g, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 200g, Herba Trifolii lupinasteris 280g, Jasminum polyanthum Franch. 160g, snow medicine 150g, Herba Seu Radix Peperomiae Tetraphyllae 120g and Melica scabrosa Trin. 100g;
Prepare according to the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 85%, reflux 2 hours, extracts, and filters acquisition first extracting solution; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 2 hours, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 hour, pulverize, sieve, obtain 300 object micropowders;
3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.2:0.3, incapsulate in housing by described capsule 's content, obtain capsule finished product.
Embodiment 2: powder
Get Herba Dracocephali tangutici 140g, Herba Thalictri Ramosi 220g, Herba Pteridis Multifidae 180g, Herba Corydalis tailensis 130g, Caulis seu folium hoyaecarnosae 120g, Anhydrite 150g, flatstiped corydalis herb 260g, Carapax pelochelydis 200g, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 220g, Herba Trifolii lupinasteris 260g, Jasminum polyanthum Franch. 200g, snow medicine 140g, Herba Seu Radix Peperomiae Tetraphyllae 150g and Melica scabrosa Trin. 80g;
Prepare according to the following steps:
The first step, is mixed in proportion described raw medicinal material, is ground into powder;
Second step, the first step is obtained powder and add in cold water and soak 10 hours, with slow fire boiling, decocting time is 4 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 3 times of the powder quality that the first step obtains;
3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 3 hours, filters acquisition second filtrate, and the quality of the water added is 2 times of the powder quality that second step obtains;
4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 100 orders;
5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 20%, and by the material pouch subpackage after mixing, every 10 grams is one bag of subpackage.
Toxicity test:
Acute toxicity testing: application mice 60, male and female half and half, body weight 23 ~ 33g, carries out acute toxicity test.Mice is divided into two groups at random, i.e. matched group and administration group, before experiment, fasting 12 hours, is dissolved in water by Chinese medicine capsules prepared by embodiments of the invention 1, (concentration is 7.28g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg (namely unit dosage form is 36.4 crude drugs/kg), and matched group gives normal saline, administration in one day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage capsule LD50>36.4 crude drug/kg of the present invention, every day, maximum dosage-feeding was 72.8 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 6.3g crude drug/day/people, adult body weight in 60KG, average dosage is 0.105g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 28g) oral administration gavage Chinese medicine of the present invention is 693 times of quantity.Therefore Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.
Long term toxicity test: Chinese medicine embodiment 1 capsule of the present invention to three groups of mices (often organize 10) by 13.35,19.26 and 38.33g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical data:
Case selection: whole 100 routine cases are my Out-patient Department or inpatient, male 22 people, women 78 people, 22 ~ 55 years old age, the course of disease 1 ~ 11 year.Filter blocking adenoma 83 example, adenoma papilliforum 17 example.Diseased region: right gland leaf 39 example, left gland leaf 52 example, two gland leaf 9 example; Symptom: Silent Neuritis tuberosity 78 serendipitous example, tracheal compression or swallow uncomfortable 11 examples, tuberosity unexpected enlargement companion pain 5 example, with hoarseness 6 example.Be divided into treatment group and matched group at random, wherein treatment group 50 people, male 11 people, women 39 people, 22 ~ 54 years old age, the course of disease 1 ~ 9 year.Filter blocking adenoma 41 example, adenoma papilliforum 9 example.Diseased region: right gland leaf 19 example, left gland leaf 26 example, two gland leaf 5 example; Symptom: Silent Neuritis tuberosity 39 serendipitous example, tracheal compression or swallow uncomfortable 6 examples, tuberosity unexpected enlargement companion pain 2 example, with hoarseness 3 example.Matched group 50 people, male 11 people, women 39 people, 24 ~ 55 years old age, the course of disease 1 ~ 11 year.Filter blocking adenoma 42 example, adenoma papilliforum 8 example.Diseased region: right gland leaf 20 example, left gland leaf 26 example, two gland leaf 4 example; Symptom: Silent Neuritis tuberosity 39 serendipitous example, tracheal compression or swallow uncomfortable 5 examples, tuberosity unexpected enlargement companion pain 3 example, with hoarseness 3 example.Two groups of ages, sex, the course of disease, diseased region, clinical manifestation and equal not statistically significants of coincident with severity degree of condition comparing difference (p>0.05).
Diagnostic criteria: the diagnostic criteria with reference to the thyroid adenoma in " Clinics and Practices of thyroid disease " of Xue Yaoming chief editor:
(1) clinical symptoms: region thyreoidea has limitation lump, mostly be Solitary nodules, circle or oval, differ in size, move up and down with swallowing, sometimes cervical region has constriction or hypopnea, can tracheas suppressed, esophagus and cause uncomfortable in chest, pharyngeal constriction, cough, swallow and be obstructed when lump is larger;
(2) auxiliary examination: ultrasound diagnosis: thyroid limitation enlargement, how circular or oval.50% periphery is sound dizzy, and the smooth of the edge, decomposes clear, has complete peplos, inner in even low echo, minority in strong or equal echo, echo rear without acoustic attenuation, partial liquefaction, stippled calcification; Radioisotope scan: radioisotope scanning can be " warm nodule ", cystic person is " cold nodule ", and thyroid absorbs 131 iodine rates normally; Determination of serum T3, T4 level increases, and increases comparatively obvious with T3.
Exclusion standard: do not meet diagnostic criteria person; Be associated with severe primary disease and the psychotics such as cardiovascular, cerebrovascular, liver, kidney and hemopoietic system; Age is below 20 years old or more than 55 years old person; Hashimoto's disease patient, or with hyperthyroidism, trachea, esophagus, the obvious person of nerve compression symptom; Gestation or women breast-feeding their children; Not by regulation medication, cannot curative effect be judged, or the not congruent judgement person that affects the treatment of data.
Therapeutic Method:
Treatment group: give the embodiment of the present invention 1 capsule, each 4, every day 3 times.1 month was 1 course for the treatment of, took 6 months continuously;
Matched group: oral levothyroxine sodium tables first week 30 μ g/d, within the 2nd week, start to be increased to 50 μ g/d, 1 month was 1 course for the treatment of, took 6 months continuously.
Curative effect judging standard: cure: tumor disappearance, clinical symptom disappearance, serological index recovers normal; Effective: tumor mass reduction more than 1/2, clinical symptoms disappears substantially, and serological index 2/3 recovers normal; Effective: tumor mass reduction 1/3 ~ 1/2, clinical symptoms is clearly better, and serological index 1/3 ~ 2/3 recovers normal; Invalid: gross tumor volume has no and obviously reduces, clinical symptoms has no and is clearly better, and serological index is not improved.
Therapeutic outcome: two groups treat 1 course for the treatment of respectively after, statistical result is see table 1 and table 2.
After table 1 liang group treatment, total effects compares (example):
Group n Cure Effective Effectively Invalid Effectively total
Treatment group 50 21 17 8 4 46(92%)
Matched group 50 10 16 11 13 37(74%)
As can be seen from Table 1, adopt treatment by Chinese herbs thyroid adenoma of the present invention, relative to Western medicine on therapeutic effect, there is significant improvement.
Number and cure rate comparative example (cure rate %) is cured stage by stage after table 2 liang group treatment
Group n Treat 2 months Treat 4 months Treat 6 months
Treatment group 21 5(10%) 16(32%) 21(42%)
Matched group 10 1(2%) 4(8%) 10(20%)
As can be seen from Table 2, adopt treatment by Chinese herbs thyroid adenoma of the present invention, relative to Western medicine, treatment the course for the treatment of on significantly shorten, namely treatment group takes effect faster.
According to the clinical statistics in above table, Chinese medicine provided by the invention have rapid-action, effective percentage is high, the advantage of safe without toxic side effect; Follow up a case by regular visits to 1 year respectively to 21 routine patients for the treatment of group clinical cure and 10 routine patients of matched group clinical cure, result is added up, and the routine patient for the treatment of group 21 is without recurrence, and relapse rate is 0% simultaneously; The routine patient of matched group 10, recurs 2 people, relapse rate 20%.
Concrete case: Zhao, women, 38 years old.The course of disease 2 years, the right body of gland of thyroid has limitation lump, in oval, differs in size, and moves up and down with swallowing; Ultrasound diagnosis: thyroid limitation enlargement, how oval, the smooth of the edge, decomposes clear, has complete peplos, and inner in even low echo, echo rear is without acoustic attenuation; Isotopic examination: warm nodule, it is normal that thyroid absorbs 131 iodine rates; Determination of serum T3, T4 level increases.Be diagnosed as thyroid adenoma.Give Chinese medicine embodiment 1 capsule of the present invention, each 4, every day 3 times, treat after 3 months, recovery from illness, follows up a case by regular visits to and does not recur for 1 year.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (9)

1. treat a Chinese medicine for thyroid adenoma, it is characterized in that, each raw medicinal material of described Chinese medicine comprises: Herba Dracocephali tangutici, Herba Thalictri Ramosi, Herba Pteridis Multifidae, Herba Corydalis tailensis, Caulis seu folium hoyaecarnosae, Anhydrite, flatstiped corydalis herb, Carapax pelochelydis, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis), Herba Trifolii lupinasteris, Jasminum polyanthum Franch., snow medicine, Herba Seu Radix Peperomiae Tetraphyllae and Melica scabrosa Trin..
2. Chinese medicine as claimed in claim 1, it is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Dracocephali tangutici 10 ~ 20 parts, Herba Thalictri Ramosi 20 ~ 30 parts, Herba Pteridis Multifidae 10 ~ 20 parts, Herba Corydalis tailensis 10 ~ 20 parts, Caulis seu folium hoyaecarnosae 5 ~ 15 parts, Anhydrite 10 ~ 20 parts, flatstiped corydalis herb 20 ~ 30 parts, Carapax pelochelydis 20 ~ 30 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 15 ~ 25 parts, Herba Trifolii lupinasteris 20 ~ 30 parts, Jasminum polyanthum Franch. 10 ~ 20 parts, snow medicine 10 ~ 20 parts, Herba Seu Radix Peperomiae Tetraphyllae 8 ~ 18 parts and Melica scabrosa Trin. 5 ~ 15 parts.
3. Chinese medicine as claimed in claim 1 or 2, it is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Dracocephali tangutici 10 ~ 15 parts, Herba Thalictri Ramosi 20 ~ 25 parts, Herba Pteridis Multifidae 15 ~ 20 parts, Herba Corydalis tailensis 12 ~ 17 parts, Caulis seu folium hoyaecarnosae 8 ~ 13 parts, Anhydrite 13 ~ 18 parts, flatstiped corydalis herb 22 ~ 27 parts, Carapax pelochelydis 20 ~ 25 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 18 ~ 23 parts, Herba Trifolii lupinasteris 25 ~ 30 parts, Jasminum polyanthum Franch. 15 ~ 20 parts, snow medicine 13 ~ 18 parts, Herba Seu Radix Peperomiae Tetraphyllae 10 ~ 15 parts and Melica scabrosa Trin. 7 ~ 12 parts.
4. the Chinese medicine as described in claims 1 to 3, is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Dracocephali tangutici 14 parts, Herba Thalictri Ramosi 22 parts, Herba Pteridis Multifidae 18 parts, Herba Corydalis tailensis 13 parts, Caulis seu folium hoyaecarnosae 12 parts, Anhydrite 15 parts, flatstiped corydalis herb 26 parts, Carapax pelochelydis 20 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 22 parts, Herba Trifolii lupinasteris 26 parts, Jasminum polyanthum Franch. 20 parts, snow medicine 14 parts, Herba Seu Radix Peperomiae Tetraphyllae 15 parts and Melica scabrosa Trin. 8 parts.
5. the Chinese medicine as described in claims 1 to 3, is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Dracocephali tangutici 12 parts, Herba Thalictri Ramosi 25 parts, Herba Pteridis Multifidae 16 parts, Herba Corydalis tailensis 15 parts, Caulis seu folium hoyaecarnosae 10 parts, Anhydrite 18 parts, flatstiped corydalis herb 24 parts, Carapax pelochelydis 24 parts, Radix Cynoglossi Amabillis (Herba Cynoglossi Amabilis) 20 parts, Herba Trifolii lupinasteris 28 parts, Jasminum polyanthum Franch. 16 parts, snow medicine 15 parts, Herba Seu Radix Peperomiae Tetraphyllae 12 parts and Melica scabrosa Trin. 10 parts.
6. the Chinese medicine as described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.
7. the Chinese medicine as described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:
The first step, is mixed in proportion described raw medicinal material, is ground into powder;
Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;
5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.
8. a preparation method for Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.
9. a preparation method for Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:
The first step, is mixed in proportion described raw medicinal material, is ground into powder;
Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;
3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;
4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;
5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.
CN201510648318.5A 2015-10-09 2015-10-09 Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof Pending CN105250749A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510648318.5A CN105250749A (en) 2015-10-09 2015-10-09 Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510648318.5A CN105250749A (en) 2015-10-09 2015-10-09 Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105250749A true CN105250749A (en) 2016-01-20

Family

ID=55090877

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510648318.5A Pending CN105250749A (en) 2015-10-09 2015-10-09 Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105250749A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105920486A (en) * 2016-06-20 2016-09-07 柳春华 Traditional Chinese medicine for treating juvenile bronchial asthma and method of preparation for same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293987A (en) * 2011-08-18 2011-12-28 闫钧 Medicine for treating thyroid adenoma
CN103272150A (en) * 2013-06-22 2013-09-04 张春治 Traditional Chinese medicine preparation for curing thyroid adenoma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293987A (en) * 2011-08-18 2011-12-28 闫钧 Medicine for treating thyroid adenoma
CN103272150A (en) * 2013-06-22 2013-09-04 张春治 Traditional Chinese medicine preparation for curing thyroid adenoma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105920486A (en) * 2016-06-20 2016-09-07 柳春华 Traditional Chinese medicine for treating juvenile bronchial asthma and method of preparation for same

Similar Documents

Publication Publication Date Title
CN102342992B (en) Chinese medicinal composition for treating insomnia and preparation method of preparation thereof
CN103990081A (en) Traditional Chinese medicine composition and application thereof in preparation of medicine for treating infant jaundice
CN104800771A (en) Traditional Chinese medicine preparation for treating children sleep terror disorder and preparation method thereof
CN103446445B (en) Traditional Chinese medicine preparation for treating qi-yin deficiency-type chronic bronchitis and preparation method thereof
CN103285343B (en) Medicine for treating liver cancer and preparation method thereof
CN103341092A (en) Preparation method of powder for treating atrophic vaginitis
CN105250749A (en) Traditional Chinese medicine for treating thyroid adenoma and preparation method thereof
CN106177477A (en) A kind of health composition for blood sugar lowering, blood fat reducing and blood pressure lowering
CN103330867A (en) Preparation method of powder for treating senile vaginitis
CN105125693A (en) Traditional Chinese medicine composition for treating acute gastritis and preparing method thereof
CN105456617A (en) Oral-administrated traditional Chinese medicine pills for treating symptom of pathogenic fire derived from stagnation of liver and preparation method thereof
CN105194509A (en) Traditional Chinese medicine composition for treating duodenal bulbar ulcer with excessive heat in stomach
CN104940777A (en) Electuary capable of treating liver-yang hyperactivity and spleen weakness type diarrhea during menstruation and preparation method thereof
CN105267745A (en) Traditional Chinese medicine composition for treating uremia and preparation method
CN106177480A (en) A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja and Herba Dendrobii
CN104840803A (en) Traditional Chinese medicine for treating thyroid adenoma due to qi depression and phlegm stagnation and preparation method thereof
CN106173606A (en) A kind of Hyperglycemic health care compositions comprising Cortex Mori and Herba Dendrobii
CN104645061A (en) Medicine for treating blood stasis stationary chronic gastric ulcer and preparation method
CN104547695B (en) It is a kind of for treating the pharmaceutical composition and its application of trigeminal neuralgia
CN104306565A (en) Traditional Chinese medicine preparation for treating qi stagnation and blood stasis type angina pectoris and preparation method thereof
CN104398849A (en) Traditional Chinese medicine composition treating dizziness
CN103330896A (en) Preparation method of powder for treating postpartum nonspecific vaginitis
CN103006957A (en) Pharmaceutical composition for preventing and treating osteoporosis and preparation method thereof
CN106389935A (en) Anticancer traditional Chinese medicine composition with effects of replenishing qi, enriching blood and improving immunity and method for preparing anticancer traditional Chinese medicine composition
CN105169167A (en) Traditional Chinese medicine composition for curing postpartum intestinal obstruction

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160120