CN113366014B - 经修饰的gip肽类似物 - Google Patents

经修饰的gip肽类似物

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Publication number
CN113366014B
CN113366014B CN201980090373.3A CN201980090373A CN113366014B CN 113366014 B CN113366014 B CN 113366014B CN 201980090373 A CN201980090373 A CN 201980090373A CN 113366014 B CN113366014 B CN 113366014B
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gip
seq
amino acid
glu
aeeac
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CN201980090373.3A
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Chinese (zh)
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CN113366014A (zh
Inventor
A·H·斯帕雷-乌尔里希
B·B·西弗森
D·里伯
M·M·罗森基尔德
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/645—Secretins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201980090373.3A 2018-12-03 2019-12-03 经修饰的gip肽类似物 Active CN113366014B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18209896.2 2018-12-03
EP18209896 2018-12-03
EP19176739.1 2019-05-27
EP19176739 2019-05-27
PCT/EP2019/083506 WO2020115048A1 (en) 2018-12-03 2019-12-03 Modified gip peptide analogues

Publications (2)

Publication Number Publication Date
CN113366014A CN113366014A (zh) 2021-09-07
CN113366014B true CN113366014B (zh) 2025-10-21

Family

ID=68731999

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980090373.3A Active CN113366014B (zh) 2018-12-03 2019-12-03 经修饰的gip肽类似物

Country Status (11)

Country Link
US (3) US12187773B2 (enExample)
EP (2) EP3891173A1 (enExample)
JP (1) JP7605747B2 (enExample)
CN (1) CN113366014B (enExample)
AU (2) AU2019391300B2 (enExample)
BR (1) BR112021010447A2 (enExample)
CA (1) CA3121043A1 (enExample)
IL (1) IL283385A (enExample)
MX (1) MX2021006505A (enExample)
SG (1) SG11202105586YA (enExample)
WO (2) WO2020115048A1 (enExample)

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US20250346647A2 (en) * 2019-12-03 2025-11-13 Antag Therapeutics Aps Optimized GIP Peptide Analogues
CN116133677A (zh) * 2020-07-06 2023-05-16 鸿绪生物医药科技（北京）有限公司 新型多肽制剂及其治疗用途
CA3185229A1 (en) * 2020-07-06 2022-01-13 Jie Han Novel polypeptide and therapeutic use thereof
IL304214B2 (en) 2021-01-20 2025-01-01 Viking Therapeutics Inc Compositions and methods for treating metabolic and liver disorders
BR112023024968A2 (pt) * 2021-06-10 2024-02-20 Antag Therapeutics Aps Tratamento da obesidade e distúrbios relacionados à obesidade
KR102873595B1 (ko) 2021-09-15 2025-10-22 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 장애의 치료를 위한 조성물 및 방법
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists
JP2025523681A (ja) * 2022-07-13 2025-07-23 杭州中美華東製薬有限公司 Ｇｌｐ－１／ｇｉｐ二重アゴニスト、その調製方法および使用
CN118255864A (zh) * 2022-12-26 2024-06-28 杭州中美华东制药有限公司 Gip受体激动剂及其用途
GB202302686D0 (en) * 2023-02-24 2023-04-12 Imperial College Innovations Ltd Novel compounds
WO2024209050A1 (en) * 2023-04-05 2024-10-10 Antag Therapeutics Aps Gip activity modulators and orthostatic intolerance
TW202529796A (zh) * 2023-11-22 2025-08-01 大陸商杭州中美華東製藥有限公司 Glp-1r/gipr雙標靶激動劑在製備動物藥的用途
WO2025154021A1 (en) * 2024-01-19 2025-07-24 Takeda Pharmaceutical Company Limited Improved gip receptor agonist peptide compounds and uses thereof
WO2025154020A1 (en) * 2024-01-19 2025-07-24 Takeda Pharmaceutical Company Limited Improved gip receptor agonist peptide compounds and uses thereof
WO2025176999A2 (en) * 2024-02-23 2025-08-28 Ip2Ipo Innovations Limited Novel compounds

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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues

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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues

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Also Published As

Publication number Publication date
US20220298218A1 (en) 2022-09-22
AU2025237957A1 (en) 2025-10-16
US20250376499A1 (en) 2025-12-11
BR112021010447A2 (pt) 2021-08-24
MX2021006505A (es) 2021-10-01
KR20210102911A (ko) 2021-08-20
CA3121043A1 (en) 2020-06-11
WO2020115049A1 (en) 2020-06-11
SG11202105586YA (en) 2021-06-29
CN113366014A (zh) 2021-09-07
JP2022509568A (ja) 2022-01-20
EP3891173A1 (en) 2021-10-13
US20220025010A1 (en) 2022-01-27
JP7605747B2 (ja) 2024-12-24
US12187773B2 (en) 2025-01-07
US12297250B2 (en) 2025-05-13
AU2019391300A1 (en) 2021-07-01
AU2019391300B2 (en) 2025-06-26
WO2020115048A1 (en) 2020-06-11
EP3891174A1 (en) 2021-10-13
IL283385A (en) 2021-07-29

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