CN113332168A - Polypeptide and ceramide compounded anti-aging repair cream and preparation method thereof - Google Patents

Polypeptide and ceramide compounded anti-aging repair cream and preparation method thereof Download PDF

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CN113332168A
CN113332168A CN202110615089.2A CN202110615089A CN113332168A CN 113332168 A CN113332168 A CN 113332168A CN 202110615089 A CN202110615089 A CN 202110615089A CN 113332168 A CN113332168 A CN 113332168A
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ceramide
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polypeptide
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林琚
余锦彪
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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Abstract

The invention discloses an anti-aging repair cream compounded by polypeptide and ceramide and a preparation method thereof. According to the invention, ceramide 1, ceramide 3 and ceramide 6II are matched with acetyl hexapeptide-8 solution, palmitoyl pentapeptide-4 solution and arginine/lysine polypeptide solution, so that wrinkles such as fine lines and dry lines of facial skin can be well improved, and meanwhile, fragile skin can be repaired.

Description

Polypeptide and ceramide compounded anti-aging repair cream and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetic manufacturing, in particular to an anti-aging repair cream compounded by polypeptide and ceramide and a preparation method thereof.
Background
Along with the importance of people on skin aging, cosmetics on the market are also endlessly abundant. At present, the anti-aging cosmetics have different forms, different effects and possibly unsafe substances, and the skin can generate uncomfortable side effects and the like in the using process.
Because the existing cosmetics have weak anti-aging effect on skin and some sensitive skin cannot use anti-aging products, how to provide a natural and safe anti-aging cosmetic is a problem to be solved urgently by related personnel in the field.
Disclosure of Invention
In view of the above, the invention provides an anti-aging repair cream compounded by polypeptide and ceramide, which has the effects of improving fine lines of facial skin, and enhancing skin elasticity and luster.
In order to achieve the purpose, the invention adopts the following technical scheme:
an anti-aging repair cream compounded by polypeptide and ceramide comprises the following raw materials:
group A materials: glycerol tri (ethyl hexanoate), hydrogenated polyisobutene, jojoba seed oil, emulsifier A, stearate, cetearyl alcohol, stearic acid, phytosterols, dimethicone, emulsifier B, dipalmitoyl hydroxyproline, tocopheryl acetate;
b group material: water, glyceryl polyether-26, betaine, Chondrus crispus extract solution, carbomer, methylparaben, allantoin, and disodium EDTA;
c group material: octyl methicone, ceramide 1, ceramide 3, ceramide 6II, skin conditioner, thickener, bisabolol;
d group of materials: water and arginine in the formula table;
e, group material: biological carbohydrate gum-1 solution, xylitol mixture, acetyl hexapeptide-8 solution, palmitoyl pentapeptide-4 solution, arginine/lysine polypeptide solution, and kava root extract solution;
f group material: butanediol, water pepper fruit and pomelo fruit extract solution, humectant;
g group material: essence, CI 19140, CI 16035.
Preferably, the anti-aging repair cream compounded by the polypeptide and the ceramide comprises the following raw materials in percentage by mass:
group A materials: 3-6% of glycerol tri (ethyl hexanoate), 3-6% of hydrogenated polyisobutene, 2-6% of jojoba seed oil, 2-4% of emulsifier A, 1-3% of stearate, 0.5-2% of cetearyl alcohol, 0.5-2% of stearate, 1-3% of phytosterol, 1-2% of polydimethylsiloxane, 1.5-3% of emulsifier B, 0.5-2% of dipalmitoyl hydroxyproline and 0.5-1% of tocopherol acetate;
b group material: the balance of water, glycerol polyether-263-6%, betaine 1-2%, Chondrus crispus extract solution 1-3%, carbomer 0.2-0.5%, methylparaben 0.1-0.25%, allantoin 0.1-0.2%, and EDTA disodium 0.05-0.15%;
c group material: 1-2% of octyl polymethylsiloxane, 10.1-0.5% of ceramide, 30.1-0.5% of ceramide, 0.1-0.5% of ceramide 6II, 2-5% of skin conditioner, 0.5-0.15% of thickening agent and 0.1-0.2% of bisabolol;
d group of materials: arginine 0.2-0.5%;
e, group material: 2-5% of biological carbohydrate gum-1 solution, 2-5% of xylitol mixture, 1-5% of acetyl hexapeptide-8 solution, 1-5% of palmitoyl pentapeptide-4 solution, 1-5% of arginine/lysine polypeptide solution and 0.5-3% of kava root extract solution;
f group material: 3-6% of butanediol, 0.5-1% of the water pepper fruit and pomelo fruit extract solution and 0.5-0.8% of humectant;
g group material: 0.05-0.2% of essence, 0.003-0. 191400.001% of CI, and 0.0003% of CI 160350.0001.
Preferably, the emulsifier A in the material in the group A comprises 54 wt% of arachidyl alcohol, 28 wt% of behenyl alcohol and 18 wt% of arachidyl glucoside; the stearate comprises 50 wt% of glyceryl stearate and 50 wt% of PEG-100 stearate; emulsifier B comprises 40 wt% of bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane, 40 wt% of methoxy PEG/PPG-25/4 polydimethylsiloxane and 20 wt% of caprylic acid/capric acid triglyceride;
the skin conditioning agent in the group C comprises 97.8 wt% of ethylhexyl palmitate, 2 wt% of trihydroxystearin, 0.19512 wt% of sodium hyaluronate, 0.00488 wt% of glucomannan; the thickener comprises 37.5 wt% of 54 wt% of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 22.5 wt% of isohexadecane, 10 wt% of polysorbate-80 and 30 wt% of water;
the xylitol mixture in the material E comprises 40 wt% xylitol-based glucoside, 28 wt% dehydrated xylitol, 16 wt% xylitol and 16 wt% water;
the humectant in the group F material comprises 6 wt% of caprylyl hydroximic acid, 6 wt% of ethylhexyl glycerin, 73 wt% of 1, 2-hexanediol and 15 wt% of water.
The invention also discloses a preparation method of the anti-aging repair cream compounded by the polypeptide and the ceramide, which comprises the following steps:
1. respectively stirring and uniformly dissolving the group D materials and the group F materials for later use;
2. stirring the group A materials, heating to 75-80 ℃ and completely dissolving;
3. stirring the materials in the group B, heating to 80-85 ℃, and completely dissolving;
4. adding the group A materials into the group B materials, homogenizing for 5-7 minutes, stirring, keeping the temperature for 15-20 minutes, and then cooling;
5. cooling to 60-65 deg.C, adding group C materials, homogenizing for 3-5 min, vacuumizing, stirring, and cooling;
6. cooling to 35-40 deg.C, sequentially adding D, E, F, G groups of materials, stirring, and dissolving completely;
filtering and discharging at 7.35-40 ℃;
8. sterilizing the packaging material to be qualified;
9. inspecting the semi-finished product, and filling;
10. and finally, packaging, inspecting and warehousing after qualification.
Compared with the prior art, the invention has the beneficial effects that: according to the invention, ceramide 1, ceramide 3 and ceramide 6II are matched with acetyl hexapeptide-8 solution, palmitoyl pentapeptide-4 solution and arginine/lysine polypeptide solution, so that wrinkles such as fine lines and dry lines of facial skin can be well improved, and meanwhile, fragile skin can be repaired.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a process flow diagram of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
An anti-aging repair cream compounded by polypeptide and ceramide comprises the following raw materials in a table 1:
table 1 formula table
Figure BDA0003097733900000041
Figure BDA0003097733900000051
Description of the Material (in accordance with the recipe Table)
Group A materials: ingredients No. 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 29 and 31 in the formula table;
b group material: ingredients No. 1, 3, 14, 25, 32, 34, 35 and 38 in the formula table;
c group material: ingredients No. 15, 18, 19, 20, 24, 27 and 36 in the formula table;
d group of materials: ingredient No. 33 in the formula table;
e, group material: 16, 17, 21, 22, 23 and 28 in the formula table;
f group material: ingredients No. 2, 26 and 30 in the formula table;
g group material: ingredients No. 37, 39 and 40 in the formula table.
The preparation method of the anti-aging repair cream compounded by the polypeptide and the ceramide comprises the following steps:
1. respectively stirring and uniformly dissolving the group D materials and the group F materials for later use;
2. stirring the group A materials, heating to 75-80 ℃ and completely dissolving;
3. stirring the materials in the group B, heating to 80-85 ℃, and completely dissolving;
4. adding the group A materials into the group B materials, homogenizing for 5-7 minutes, stirring, keeping the temperature for 15-20 minutes, and then cooling;
5. cooling to 60-65 deg.C, adding group C materials, homogenizing for 3-5 min, vacuumizing, stirring, and cooling;
6. cooling to 35-40 deg.C, sequentially adding D, E, F, G groups of materials, stirring, and dissolving completely;
filtering and discharging at 7.35-40 ℃;
8. sterilizing the packaging material to be qualified;
9. inspecting the semi-finished product, and filling;
10. and finally, packaging, inspecting and warehousing after qualification.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (4)

1. The anti-aging repair cream compounded by the polypeptide and the ceramide is characterized by comprising the following raw materials:
group A materials: glycerol tri (ethyl hexanoate), hydrogenated polyisobutene, jojoba seed oil, emulsifier A, stearate, cetearyl alcohol, stearic acid, phytosterols, dimethicone, emulsifier B, dipalmitoyl hydroxyproline, tocopheryl acetate;
b group material: water, glyceryl polyether-26, betaine, Chondrus crispus extract solution, carbomer, methylparaben, allantoin, and disodium EDTA;
c group material: octyl methicone, ceramide 1, ceramide 3, ceramide 6II, skin conditioner, thickener, bisabolol;
d group of materials: water and arginine in the formula table;
e, group material: biological carbohydrate gum-1 solution, xylitol mixture, acetyl hexapeptide-8 solution, palmitoyl pentapeptide-4 solution, arginine/lysine polypeptide solution, and kava root extract solution;
f group material: butanediol, water pepper fruit and pomelo fruit extract solution, humectant;
g group material: essence, CI 19140, CI 16035.
2. The anti-aging repair cream compounded by the polypeptide and the ceramide according to claim 1 is characterized by comprising the following raw materials in percentage by mass:
group A materials: 3-6% of glycerol tri (ethyl hexanoate), 3-6% of hydrogenated polyisobutene, 2-6% of jojoba seed oil, 2-4% of emulsifier A, 1-3% of stearate, 0.5-2% of cetearyl alcohol, 0.5-2% of stearate, 1-3% of phytosterol, 1-2% of polydimethylsiloxane, 1.5-3% of emulsifier B, 0.5-2% of dipalmitoyl hydroxyproline and 0.5-1% of tocopherol acetate;
b group material: water, glycerol polyether-263-6%, betaine 1-2%, Chondrus crispus extract solution 1-3%, carbomer 0.2-0.5%, methylparaben 0.1-0.25%, allantoin 0.1-0.2%, and EDTA disodium 0.05-0.15%;
c group material: 1-2% of octyl polymethylsiloxane, 10.1-0.5% of ceramide, 30.1-0.5% of ceramide, 0.1-0.5% of ceramide 6II, 2-5% of skin conditioner, 0.5-0.15% of thickening agent and 0.1-0.2% of bisabolol;
d group of materials: arginine 0.2-0.5%;
e, group material: 2-5% of biological carbohydrate gum-1 solution, 2-5% of xylitol mixture, 1-5% of acetyl hexapeptide-8 solution, 1-5% of palmitoyl pentapeptide-4 solution, 1-5% of arginine/lysine polypeptide solution and 0.5-3% of kava root extract solution;
f group material: 3-6% of butanediol, 0.5-1% of the water pepper fruit and pomelo fruit extract solution and 0.5-0.8% of humectant;
g group material: 0.05-0.2% of essence, 0.003-0. 191400.001% of CI, and 0.0003% of CI 160350.0001.
3. The anti-aging repair cream compounded by the polypeptide and the ceramide as the claim 1 or 2,
the emulsifier A in the material A comprises 54 wt% of arachidyl alcohol, 28 wt% of behenyl alcohol and 18 wt% of arachidyl glucoside; the stearate comprises 50 wt% of glyceryl stearate and 50 wt% of PEG-100 stearate; emulsifier B comprises 40 wt% of bis-PEG/PPG-20/5 PEG/PPG-20/5 polydimethylsiloxane, 40 wt% of methoxy PEG/PPG-25/4 polydimethylsiloxane and 20 wt% of caprylic acid/capric acid triglyceride;
the skin conditioning agent in the group C comprises 97.8 wt% of ethylhexyl palmitate, 2 wt% of trihydroxystearin, 0.19512 wt% of sodium hyaluronate, 0.00488 wt% of glucomannan; the thickener comprises 37.5 wt% of 54 wt% of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 22.5 wt% of isohexadecane, 10 wt% of polysorbate-80 and 30 wt% of water;
the xylitol mixture in the material E comprises 40 wt% xylitol-based glucoside, 28 wt% dehydrated xylitol, 16 wt% xylitol and 16 wt% water;
the humectant in the group F material comprises 6 wt% of caprylyl hydroximic acid, 6 wt% of ethylhexyl glycerin, 73 wt% of 1, 2-hexanediol and 15 wt% of water.
4. The preparation method of the anti-aging cream compounded by the polypeptide and the ceramide according to any one of claims 1 to 3, which is characterized by comprising the following steps:
1. respectively stirring and uniformly dissolving the group D materials and the group F materials for later use;
2. stirring the group A materials, heating to 75-80 ℃ and completely dissolving;
3. stirring the materials in the group B, heating to 80-85 ℃, and completely dissolving;
4. adding the group A materials into the group B materials, homogenizing for 5-7 minutes, stirring, keeping the temperature for 15-20 minutes, and then cooling;
5. cooling to 60-65 deg.C, adding group C materials, homogenizing for 3-5 min, vacuumizing, stirring, and cooling;
6. cooling to 35-40 deg.C, sequentially adding D, E, F, G groups of materials, stirring, and dissolving completely;
filtering and discharging at 7.35-40 ℃;
8. sterilizing the packaging material to be qualified;
9. inspecting the semi-finished product, and filling;
10. and finally, packaging, inspecting and warehousing after qualification.
CN202110615089.2A 2021-06-02 2021-06-02 Polypeptide and ceramide compounded anti-aging repair cream and preparation method thereof Pending CN113332168A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432204A (en) * 2022-03-01 2022-05-06 国妆(广州)科技有限公司 Repair cream with effects of relieving skin inflammation and repairing skin

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109674734A (en) * 2019-01-22 2019-04-26 郑娇娇 It is a kind of with moisturizing, maintenance, releive, the composition of Antiageing effect and its application
CN109953926A (en) * 2019-04-09 2019-07-02 中美杜克(广州)护肤研究中心(普通合伙) Five crease-resistant, Antiageing effect skin care item of dimension and preparation method thereof
CN112089657A (en) * 2020-09-12 2020-12-18 文艳 Preparation method of wrinkle-removing and anti-aging cream

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109674734A (en) * 2019-01-22 2019-04-26 郑娇娇 It is a kind of with moisturizing, maintenance, releive, the composition of Antiageing effect and its application
CN109953926A (en) * 2019-04-09 2019-07-02 中美杜克(广州)护肤研究中心(普通合伙) Five crease-resistant, Antiageing effect skin care item of dimension and preparation method thereof
CN112089657A (en) * 2020-09-12 2020-12-18 文艳 Preparation method of wrinkle-removing and anti-aging cream

Non-Patent Citations (1)

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Title
广州悦妆企业管理有限公司: "《法蓝泉鎏光御龄修护霜》", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20210309135246EUT8Y&NID=20210309135246EUT8Y》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432204A (en) * 2022-03-01 2022-05-06 国妆(广州)科技有限公司 Repair cream with effects of relieving skin inflammation and repairing skin
CN114432204B (en) * 2022-03-01 2024-03-15 国妆(广州)科技有限公司 Repairing cream with skin inflammation relieving and repairing effects

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