CN113230451A - 一种可注射的皮肤填充剂及其制备方法 - Google Patents

一种可注射的皮肤填充剂及其制备方法 Download PDF

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Publication number
CN113230451A
CN113230451A CN202110360171.5A CN202110360171A CN113230451A CN 113230451 A CN113230451 A CN 113230451A CN 202110360171 A CN202110360171 A CN 202110360171A CN 113230451 A CN113230451 A CN 113230451A
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China
Prior art keywords
dermal filler
sodium hyaluronate
mixed solution
polyester
suspension
Prior art date
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Pending
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CN202110360171.5A
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English (en)
Chinese (zh)
Inventor
王晓梅
崔立国
石旭东
崔毅
庄秀丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHANGCHUN SINOBIOMATERIALS CO LTD
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CHANGCHUN SINOBIOMATERIALS CO LTD
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Application filed by CHANGCHUN SINOBIOMATERIALS CO LTD filed Critical CHANGCHUN SINOBIOMATERIALS CO LTD
Priority to CN202110360171.5A priority Critical patent/CN113230451A/zh
Priority to PCT/CN2021/103197 priority patent/WO2022205645A1/fr
Publication of CN113230451A publication Critical patent/CN113230451A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202110360171.5A 2021-04-02 2021-04-02 一种可注射的皮肤填充剂及其制备方法 Pending CN113230451A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202110360171.5A CN113230451A (zh) 2021-04-02 2021-04-02 一种可注射的皮肤填充剂及其制备方法
PCT/CN2021/103197 WO2022205645A1 (fr) 2021-04-02 2021-06-29 Charge dermique injectable et son procédé de préparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110360171.5A CN113230451A (zh) 2021-04-02 2021-04-02 一种可注射的皮肤填充剂及其制备方法

Publications (1)

Publication Number Publication Date
CN113230451A true CN113230451A (zh) 2021-08-10

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CN202110360171.5A Pending CN113230451A (zh) 2021-04-02 2021-04-02 一种可注射的皮肤填充剂及其制备方法

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Country Link
CN (1) CN113230451A (fr)
WO (1) WO2022205645A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730652A (zh) * 2021-09-01 2021-12-03 北京大清生物技术股份有限公司 一种注射用混合凝胶及其制备方法和应用
CN115282336A (zh) * 2022-08-26 2022-11-04 浙江天妍生物科技有限公司 一种含脂肪族聚酯微球多糖混合凝胶及其制备方法和应用
CN115475284A (zh) * 2022-09-14 2022-12-16 华东理工大学 一种具有三维多孔结构的微球及其制备方法
CN115584037A (zh) * 2022-10-19 2023-01-10 上海威高医疗技术发展有限公司 一种含聚合物微球的交联凝胶材料、其制备方法和注射填充剂
WO2023061201A1 (fr) * 2021-10-12 2023-04-20 北京蓝晶微生物科技有限公司 Microsphères de polyhydroxyalcanoate injectables et leur procédé de préparation
WO2023197419A1 (fr) * 2022-04-14 2023-10-19 珠海麦得发生物科技股份有限公司 Microsphère injectable d'acide hyaluronique, procédé de préparation associé et utilisation associée

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CN1538825A (zh) * 2001-06-29 2004-10-20 ¸ 可生物降解的可注射植入物及其制备方法和用途
US20070031503A1 (en) * 2003-09-08 2007-02-08 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid modification products and drug carrier therefrom
CN101693111A (zh) * 2009-10-15 2010-04-14 清华大学 一种提高聚乳酸类微球对水溶性蛋白包封率的方法
CN104147640A (zh) * 2013-05-16 2014-11-19 吴学森 右旋聚乳酸微纳米颗粒用作美容整形填充物及其制备方法
CN107441090A (zh) * 2017-08-24 2017-12-08 青岛正大海尔制药有限公司 一种托匹司他微球制剂及其制备方法
JP2018095616A (ja) * 2016-12-15 2018-06-21 国立大学法人 宮崎大学 アドレノメデュリン徐放性製剤
CN109010910A (zh) * 2018-08-24 2018-12-18 普丽妍（南京）医疗科技有限公司 一种可注射左旋聚乳酸微球的制备方法
CN110327497A (zh) * 2019-07-31 2019-10-15 易浦润（上海）生物技术有限公司 一种含微球的注射用凝胶及其制备方法
CN111905147A (zh) * 2020-08-17 2020-11-10 刘小雄 一种美容整形注射材料及其注射方法

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KR100680134B1 (ko) * 2004-06-10 2007-02-08 박우삼 무세포 진피를 주사가능하도록 입자 형태로 가공한 필러
CN106267341A (zh) * 2016-08-30 2017-01-04 圆容生物医药无锡有限公司 一种可组织诱导生物医用材料
CN106474567B (zh) * 2016-11-16 2019-08-02 浙江省人民医院 一种柔性人工皮肤及制备方法
CN108815582A (zh) * 2018-07-11 2018-11-16 中国科学院上海高等研究院 一种湿度响应人工皮肤及其制备方法和应用
CN111298195A (zh) * 2019-11-13 2020-06-19 长春圣博玛生物材料有限公司 一种复合微米材料、皮肤填充剂及其制备方法和应用
CN110787319A (zh) * 2019-11-19 2020-02-14 上海摩漾生物科技有限公司 用于面部美容提拉的植入物及其应用

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CN1538825A (zh) * 2001-06-29 2004-10-20 ¸ 可生物降解的可注射植入物及其制备方法和用途
US20070031503A1 (en) * 2003-09-08 2007-02-08 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid modification products and drug carrier therefrom
CN101693111A (zh) * 2009-10-15 2010-04-14 清华大学 一种提高聚乳酸类微球对水溶性蛋白包封率的方法
CN104147640A (zh) * 2013-05-16 2014-11-19 吴学森 右旋聚乳酸微纳米颗粒用作美容整形填充物及其制备方法
JP2018095616A (ja) * 2016-12-15 2018-06-21 国立大学法人 宮崎大学 アドレノメデュリン徐放性製剤
CN107441090A (zh) * 2017-08-24 2017-12-08 青岛正大海尔制药有限公司 一种托匹司他微球制剂及其制备方法
CN109010910A (zh) * 2018-08-24 2018-12-18 普丽妍（南京）医疗科技有限公司 一种可注射左旋聚乳酸微球的制备方法
CN110327497A (zh) * 2019-07-31 2019-10-15 易浦润（上海）生物技术有限公司 一种含微球的注射用凝胶及其制备方法
CN111905147A (zh) * 2020-08-17 2020-11-10 刘小雄 一种美容整形注射材料及其注射方法

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730652A (zh) * 2021-09-01 2021-12-03 北京大清生物技术股份有限公司 一种注射用混合凝胶及其制备方法和应用
WO2023061201A1 (fr) * 2021-10-12 2023-04-20 北京蓝晶微生物科技有限公司 Microsphères de polyhydroxyalcanoate injectables et leur procédé de préparation
WO2023197419A1 (fr) * 2022-04-14 2023-10-19 珠海麦得发生物科技股份有限公司 Microsphère injectable d'acide hyaluronique, procédé de préparation associé et utilisation associée
CN115282336A (zh) * 2022-08-26 2022-11-04 浙江天妍生物科技有限公司 一种含脂肪族聚酯微球多糖混合凝胶及其制备方法和应用
CN115475284A (zh) * 2022-09-14 2022-12-16 华东理工大学 一种具有三维多孔结构的微球及其制备方法
CN115475284B (zh) * 2022-09-14 2024-02-02 华东理工大学 一种具有三维多孔结构的微球及其制备方法
CN115584037A (zh) * 2022-10-19 2023-01-10 上海威高医疗技术发展有限公司 一种含聚合物微球的交联凝胶材料、其制备方法和注射填充剂

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