CN113191464A - Non-fixed biological reagent intelligent management system - Google Patents

Non-fixed biological reagent intelligent management system Download PDF

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Publication number
CN113191464A
CN113191464A CN202011623800.0A CN202011623800A CN113191464A CN 113191464 A CN113191464 A CN 113191464A CN 202011623800 A CN202011623800 A CN 202011623800A CN 113191464 A CN113191464 A CN 113191464A
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China
Prior art keywords
reagent
information
cabinet
unit
biological
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CN202011623800.0A
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Chinese (zh)
Inventor
黄景锟
张鹏
何杨星
况凤超
仓超
李斌
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Hangzhou Shared Experimental Technology Development Co ltd
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Hangzhou Shared Experimental Technology Development Co ltd
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06KGRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K17/00Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations
    • G06K17/0022Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations arrangements or provisious for transferring data to distant stations, e.g. from a sensing device
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06KGRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K17/00Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations
    • G06K17/0022Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations arrangements or provisious for transferring data to distant stations, e.g. from a sensing device
    • G06K17/0029Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations arrangements or provisious for transferring data to distant stations, e.g. from a sensing device the arrangement being specially adapted for wireless interrogation of grouped or bundled articles tagged with wireless record carriers
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07CTIME OR ATTENDANCE REGISTERS; REGISTERING OR INDICATING THE WORKING OF MACHINES; GENERATING RANDOM NUMBERS; VOTING OR LOTTERY APPARATUS; ARRANGEMENTS, SYSTEMS OR APPARATUS FOR CHECKING NOT PROVIDED FOR ELSEWHERE
    • G07C9/00Individual registration on entry or exit
    • G07C9/00174Electronically operated locks; Circuits therefor; Nonmechanical keys therefor, e.g. passive or active electrical keys or other data carriers without mechanical keys
    • G07C9/00571Electronically operated locks; Circuits therefor; Nonmechanical keys therefor, e.g. passive or active electrical keys or other data carriers without mechanical keys operated by interacting with a central unit

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention provides an intelligent management system of non-fixed biological reagents, which is used for leading an administrator to manage the biological reagents in a laboratory, and is characterized by comprising the following components: at least one reagent cabinet for storing biological reagents requiring low-temperature environment or normal-temperature environment; a plurality of laboratory staff terminals; the reagent cabinet comprises a cabinet body, a temperature adjusting part which is positioned in the cabinet body and used for generating a low-temperature environment or a normal-temperature environment, a plurality of placing layers which are positioned in the cabinet body and used for bearing reagent bottles with reagent labels containing reagent identification information, a plurality of judging parts, a cabinet door, a locking part, a sensing part, an identification part, a reagent cabinet communication part and a reagent cabinet control part, and the management server comprises a reagent related information storage part, a reagent cabinet information storage part, a retrieval acquisition part, a related information updating part, a reagent stock determination part, a storage cabinet number retrieval acquisition part, a service side communication part and a service side control part.

Description

Non-fixed biological reagent intelligent management system
Technical Field
The invention relates to an intelligent management system for non-immobilized biological reagents.
Background
Biological reagents are common reagent types needed in laboratories, however, different biological reagents have different properties, so that reagent cabinets with different temperatures are needed to store different biological reagents in the laboratories in a targeted manner, thereby preventing the biological reagents from deteriorating before being used.
However, different biological reagents need different reagent cabinets to be stored, which aggravates the disordered management of the reagents in the laboratory, and easily causes the problems of misplacing, mistakenly taking, difficulty in searching and the like of the biological reagents, and the administrator also has difficulty in effectively monitoring the biological reagents in the reagent cabinets, and cannot accurately know what biological reagents and the state information such as the quantity of the biological reagents are specifically stored in each reagent cabinet, so that effective statistics and management cannot be performed, and the daily operations of scrapping, purchasing and the like of the administrator on the biological reagents are influenced.
Disclosure of Invention
In order to solve the problems, the invention provides an intelligent management system of non-fixed biological reagents, which can accurately monitor and manage the biological reagents in a laboratory, so as to help a manager to simply and effectively manage the biological reagents, and the invention adopts the following technical scheme:
the invention provides an intelligent management system of non-fixed biological reagents, which is used for leading an administrator to manage the biological reagents in a laboratory, and is characterized by comprising the following components: at least one reagent cabinet for storing biological reagents requiring low-temperature environment or normal-temperature environment; a plurality of laboratory staff terminals respectively held by laboratory staff having different identification information; an administrator terminal held by an administrator who manages the reagent; and a management server, which is respectively connected with the reagent cabinet, the laboratory technician terminal and the administrator terminal in a communication way, wherein the reagent cabinet comprises a cabinet body, a temperature adjusting part which is positioned in the cabinet body and used for generating a low-temperature environment or a normal-temperature environment, a plurality of placing layers which are positioned in the cabinet body and used for bearing reagent bottles with reagent labels containing reagent identification information, a plurality of identification parts which are respectively arranged corresponding to the placing layers and used for reading the reagent labels, a cabinet door arranged on the cabinet body, a locking part used for locking the cabinet door, an induction part used for inducing the opening and closing state of the cabinet door, an identification part used for identifying the identification information of the laboratory technician, a reagent cabinet communication part and a reagent cabinet control part, the laboratory technician terminal comprises a laboratory side picture storage part, a laboratory side input display part and a laboratory side communication part, the administrator terminal comprises a management side picture storage part and a management side input display part, the management server comprises a reagent related information storage part, a reagent cabinet information storage part, a retrieval acquisition part, a related information updating part, a reagent stock determination part, a storage cabinet number retrieval acquisition part, a service side communication part and a service side control part, wherein the reagent related information storage part at least stores the reagent name of each biological reagent, storage temperature information representing the required temperature of the biological reagent when the biological reagent is stored, and corresponding reagent position information comprising the cabinet number of the reagent cabinet where the reagent bottle is located and the layer number of the placed layer, the reagent cabinet information storage part stores the cabinet number of each reagent cabinet and the environmental temperature information adjusted by the temperature adjustment part in the corresponding reagent cabinet, the experiment side screen storage part also stores a discard handling screen, the management side screen storage part stores a prompt information display screen and a purchase reagent information input screen, and once the identification part identifies the identification information, the reagent cabinet control part controls the reagent cabinet communication part to send the identification information to the management server for judgment, controls the locking part to unlock the door of the laboratory technician and extract the required biological reagent in the placing layer when receiving the door opening permission signal fed back from the management server, controls the judging part to judge to obtain the reagent judging information of the corresponding placing layer once the sensing part senses the opening of the door, further controls the reagent cabinet communication part to correspondingly send the judged reagent judging information, the layer number of the corresponding placing layer and the cabinet number of the reagent cabinet to the management server, controls the relevant information updating part to update the reagent relevant information storage part according to the received reagent position information, and displays a scrapping handling picture to allow the laboratory technician to input the reagent judging information of the biological reagent to be scrapped once the laboratory technician runs out the biological reagent and needs to perform scrapping handling procedures The identification information is used as scrap reagent identification information to conduct scrap handling, once a laboratory technician confirms the scrap handling, the experimental side communication part sends scrap reagent identification information and identification information to the management server, the service side control part controls the related information updating part to update according to the received scrap reagent identification information and the related reagent information storage part, controls the reagent stock judging part to judge whether the quantity of the corresponding biological reagent is lower than the preset reagent stock quantity according to the received reagent identification information, once the quantity of the corresponding biological reagent is lower than the reagent stock quantity, the service side control part controls the service side communication part to send purchase prompting information containing a reagent name corresponding to the received reagent position information to the management terminal, the management side input display part displays a prompting information display screen and displays the purchase prompting information in the prompting information display screen to prompt the management to purchase the corresponding biological reagent, further, after the administrator purchases the biological reagent, the purchased reagent information input screen is displayed so that the administrator inputs purchased reagent information including at least a reagent name of the purchased biological reagent and storage temperature information and transmits the purchased reagent information to the management server, the service-side control unit controls the relevant information update unit to update the reagent-related information storage unit based on the purchased reagent information, and controlling the storage cabinet number retrieval and acquisition part to retrieve the reagent cabinet information storage part based on the storage temperature information in the purchased reagent information and acquire the cabinet number of the reagent cabinet of which the environmental temperature information accords with the storage temperature information as the storage cabinet number, further controlling the service side communication part to send the storage cabinet number back to the administrator terminal, and displaying the storage cabinet number in a storage cabinet number display frame by the management side input display part so as to enable the administrator to place the purchased biological reagent in any position of any placement layer of the reagent cabinet corresponding to the storage cabinet number.
Action and Effect of the invention
According to the non-fixed biological reagent intelligent management system, the reagent labels are arranged for all biological reagents in the laboratory, the reagents are judged through the judgment parts arranged in the reagent cabinets, once a laboratory worker extracts the biological reagents from the reagent cabinets, the related information updating parts can update the information of the corresponding biological reagents according to the reagent judgment information judged by the judgment parts, and therefore the management server can accurately manage the positions and the number of all the biological reagents in the laboratory. Meanwhile, after the laboratory reagent is scrapped and updated by the related information updating part, the reagent stock determining part can also determine whether the stock of the biological reagent is lower than the preset reagent stock number, so that a manager is timely reminded of purchasing operation when a certain type of biological reagent needs to be supplemented in a laboratory, further, the manager can also obtain the number of a reagent cabinet capable of properly storing the biological reagent according to the storage temperature information of the biological reagent by the storage cabinet number retrieval and acquisition part after purchasing the reagent, the manager can conveniently place the purchased biological reagent in the corresponding reagent cabinet, the energy consumed for managing the reagent scrapping and purchasing in the laboratory is greatly saved, and the biological reagent in the laboratory is effectively managed.
Drawings
FIG. 1 is a schematic structural diagram of an intelligent management system for non-immobilized biological agents according to one embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a reagent cabinet according to a first embodiment of the present invention;
FIG. 3 is a schematic view showing the placement of a reagent bottle according to a first embodiment of the present invention;
FIG. 4 is a functional block diagram of a reagent cabinet according to a first embodiment of the present invention;
FIG. 5 is a diagram illustrating the contents stored in the bin number layer number storage unit according to an embodiment of the present invention;
FIG. 6 is a block diagram of a management server according to an embodiment of the present invention;
FIG. 7 is a diagram illustrating the contents of the reagent-related information storage unit according to one embodiment of the present invention;
FIG. 8 is a diagram showing the contents stored in the reagent kit information storage unit according to the embodiment of the present invention;
FIG. 9 is a diagram illustrating the content of the extracted information according to the first embodiment of the present invention;
FIG. 10 is a block diagram of a laboratory technician terminal according to an embodiment of the present invention;
FIG. 11 is a diagram illustrating an information display screen according to an embodiment of the present invention;
fig. 12 is a block diagram of an administrator terminal according to a first embodiment of the present invention;
FIG. 13 is a flow chart of a reagent request process in accordance with one embodiment of the present invention;
FIG. 14 is a flow chart of a reagent extraction and return process in accordance with an embodiment of the present invention;
FIG. 15 is a schematic structural diagram of a reagent cabinet according to a second embodiment of the present invention; and
FIG. 16 is a schematic structural diagram of an intelligent management system for non-immobilized bioreagent according to a third embodiment of the present invention.
Detailed Description
Hereinafter, the experiment-based non-immobilized bioreagent intelligent management system according to the present invention will be described in detail with reference to the accompanying drawings.
In one aspect, the present invention provides an intelligent non-immobilized biological reagent management system for allowing an administrator to manage a biological reagent in a laboratory, the intelligent non-immobilized biological reagent management system including: at least one reagent cabinet for storing biological reagents requiring low-temperature environment or normal-temperature environment; a plurality of laboratory staff terminals respectively held by laboratory staff having different identification information; an administrator terminal held by an administrator who manages the reagent; and a management server, which is respectively connected with the reagent cabinet, the laboratory technician terminal and the administrator terminal in a communication way, wherein the reagent cabinet comprises a cabinet body, a temperature adjusting part which is positioned in the cabinet body and used for generating a low-temperature environment or a normal-temperature environment, a plurality of placing layers which are positioned in the cabinet body and used for bearing reagent bottles with reagent labels containing reagent identification information, a plurality of identification parts which are respectively arranged corresponding to the placing layers and used for reading the reagent labels, a cabinet door arranged on the cabinet body, a locking part used for locking the cabinet door, an induction part used for inducing the opening and closing state of the cabinet door, an identification part used for identifying the identification information of the laboratory technician, a reagent cabinet communication part and a reagent cabinet control part, the laboratory technician terminal comprises a laboratory side picture storage part, a laboratory side input display part and a laboratory side communication part, the administrator terminal comprises a management side picture storage part and a management side input display part, the management server comprises a reagent related information storage part, a reagent cabinet information storage part, a retrieval acquisition part, a related information updating part, a reagent stock determination part, a storage cabinet number retrieval acquisition part, a service side communication part and a service side control part, wherein the reagent related information storage part at least stores the reagent name of each biological reagent, storage temperature information representing the required temperature of the biological reagent when the biological reagent is stored, and corresponding reagent position information comprising the cabinet number of the reagent cabinet where the reagent bottle is located and the layer number of the placed layer, the reagent cabinet information storage part stores the cabinet number of each reagent cabinet and the environmental temperature information adjusted by the temperature adjustment part in the corresponding reagent cabinet, the experiment side screen storage part also stores a discard handling screen, the management side screen storage part stores a prompt information display screen and a purchase reagent information input screen, and once the identification part identifies the identification information, the reagent cabinet control part controls the reagent cabinet communication part to send the identification information to the management server for judgment, controls the locking part to unlock the door of the laboratory technician and extract the required biological reagent in the placing layer when receiving the door opening permission signal fed back from the management server, controls the judging part to judge to obtain the reagent judging information of the corresponding placing layer once the sensing part senses the opening of the door, further controls the reagent cabinet communication part to correspondingly send the judged reagent judging information, the layer number of the corresponding placing layer and the cabinet number of the reagent cabinet to the management server, controls the relevant information updating part to update the reagent relevant information storage part according to the received reagent position information, and displays a scrapping handling picture to allow the laboratory technician to input the reagent judging information of the biological reagent to be scrapped once the laboratory technician runs out the biological reagent and needs to perform scrapping handling procedures The identification information is used as scrap reagent identification information to conduct scrap handling, once a laboratory technician confirms the scrap handling, the experimental side communication part sends scrap reagent identification information and identification information to the management server, the service side control part controls the related information updating part to update according to the received scrap reagent identification information and the related reagent information storage part, controls the reagent stock judging part to judge whether the quantity of the corresponding biological reagent is lower than the preset reagent stock quantity according to the received reagent identification information, once the quantity of the corresponding biological reagent is lower than the reagent stock quantity, the service side control part controls the service side communication part to send purchase prompting information containing a reagent name corresponding to the received reagent position information to the management terminal, the management side input display part displays a prompting information display screen and displays the purchase prompting information in the prompting information display screen to prompt the management to purchase the corresponding biological reagent, further, after the administrator purchases the biological reagent, the purchased reagent information input screen is displayed so that the administrator inputs purchased reagent information including at least a reagent name of the purchased biological reagent and storage temperature information and transmits the purchased reagent information to the management server, the service-side control unit controls the relevant information update unit to update the reagent-related information storage unit based on the purchased reagent information, and controlling the storage cabinet number retrieval and acquisition part to retrieve the reagent cabinet information storage part based on the storage temperature information in the purchased reagent information and acquire the cabinet number of the reagent cabinet of which the environmental temperature information accords with the storage temperature information as the storage cabinet number, further controlling the service side communication part to send the storage cabinet number back to the administrator terminal, and displaying the storage cabinet number in a storage cabinet number display frame by the management side input display part so as to enable the administrator to place the purchased biological reagent in any position of any placement layer of the reagent cabinet corresponding to the storage cabinet number.
In the above embodiment, the management server may further include a quality-guarantee period determination unit and a discard information generation unit, the management-side screen storage unit further stores a discard information display screen, the reagent-related information storage unit further stores quality-guarantee period information of each of the biological reagents, the service-side control unit periodically controls the quality-guarantee period determination unit to sequentially determine whether each of the biological reagents exceeds the quality-guarantee period according to the quality-guarantee period information and the current time, the service-side control unit controls the discard information generation unit to generate reagent discard information according to a reagent name and reagent position information corresponding to the biological reagent exceeding the quality-guarantee period, and controls the service-side communication unit to transmit the reagent discard information to the administrator terminal, and the management-side input display unit displays the discard information display screen and the reagent discard information in the discard information display screen to allow the administrator to discard the corresponding biological reagent Corresponding biological reagents were processed and purchased.
In the above embodiment, the reagent storage system may further include a reagent storage unit, wherein the reagent storage unit is configured to store reagent labels, the reagent storage unit is configured to store the reagent labels, and the discrimination unit is configured to discriminate the RFID labels, and is configured to be disposed on a position on the layer eaves, which is close to an outer side surface of the insulation cabinet door, where the low temperature environment is an ultra-low temperature environment of-30 ℃ to-100 ℃.
In the above-described embodiment, the management server may further include a rough position determination unit, the reagent position information may further include rough position information corresponding to a rough position of the reagent bottle on the placement layer, at least two determination units having different part numbers may be provided below each layer edge, when the reagent tank communication unit transmits the reagent determination information obtained by the determination to the management server in correspondence with the layer number of the corresponding placement layer and the tank number of the low-temperature reagent tank, the part number of the corresponding determination unit may be further transmitted to the management server, and when the management server receives the reagent determination information, the part number, the layer number, and the tank number transmitted from the low-temperature reagent tank, the service-side control unit may further control the rough position determination unit to determine the rough position information corresponding to the reagent determination information based on the reagent determination information and the part number.
In the above embodiment, the system may further include a reagent request screen and an extraction information display screen stored in the lab-side screen storage unit, wherein the lab-side input display unit displays the reagent request screen to allow the experimenter to input a name of a biological reagent to be extracted as a required reagent name, wherein the lab-side communication unit transmits the required reagent name to the management server when the experimenter confirms the required reagent name, wherein the service-side control unit controls the search acquisition unit to search the reagent-related information storage unit according to the required reagent name and acquire corresponding reagent location information, and further controls the service-side communication unit to transmit the reagent location information and the required reagent name as extraction information to the experimenter terminal, wherein the lab-side input display unit displays the extraction information display screen and displays the received extraction information on the screen, thereby leading the experimenter to go to the corresponding reagent cabinet according to the extraction information and search and extract the required biological reagent at the rough position on the corresponding placing layer.
In the above-described embodiment, the management server may further include a discard information generating unit, wherein the service-side control unit controls the discard information generating unit to generate reagent discard information according to the discard reagent identification information and the identification information, and controls the service-side communication unit to send the reagent discard information to the administrator terminal, and the administration-side input display unit displays a discard information display screen and displays the reagent discard information on the discard information display screen, so that the administrator discards the corresponding biological reagent and purchases the corresponding biological reagent.
In the above embodiment, the present invention may further include: the scrapping reagent cabinet is used for storing scrapped biological reagents which are used up by a laboratory technician and are scrapped, wherein the reagent cabinet information storage part is also stored with the cabinet number of the scrapping reagent cabinet, when the service side control part controls the scrapping information generation part to generate reagent scrapping information, the scrapping record storage part is also controlled to correspondingly store the received scrapping reagent judgment information and identification information, the service side communication part is further controlled to send the cabinet number of the scrapping reagent cabinet to a corresponding laboratory technician terminal, and the laboratory side input display part is further used for displaying the cabinet number of the scrapping reagent cabinet in a scrapping handling picture to enable the laboratory technician to return the scrapped biological reagents to any position on any placing layer of the scrapping reagent cabinet.
In the above-described embodiment, the management server may further include an acquisition time storage unit that further stores a deadline notification screen, and a holding time determination unit that controls the acquisition time storage unit to store a current time as an extraction time in association with the received reagent discrimination information and the identification information when the control-related-information update unit updates the reagent-related-information storage unit based on the received reagent position information, wherein the holding time determination unit periodically determines whether a time difference between each extraction time and the current time exceeds the reagent holding time or the limited holding time based on a preset reagent holding time and the limited holding time, and when it is determined that the reagent holding time has exceeded, the service-side control unit controls the service-side communication unit to transmit deadline notification information including the extraction time to a corresponding laboratory technician terminal based on the identification information, the experimental side input display part displays a time limit reminding picture and displays time limit reminding information in the picture to remind an experimenter, once the condition that the limited holding time is exceeded is judged, the service side control part controls the service side communication part to send the time limit reminding information and identification information to the administrator terminal, and the management side input display part displays the time limit management picture and displays the time limit reminding information and the identification information in the picture to be processed by the administrator.
In the above-described embodiment, the experimental-side screen storage unit may further store a delay processing screen, the experimental-side input display unit may display the delay processing screen to allow the experimenter to input reagent identification information of a reagent to be delayed and perform delay processing when the experimenter needs to perform a delay processing procedure, the experimental-side communication unit may transmit the input reagent identification information and identification information to the management server when the experimenter confirms that the delay processing is performed, the service-side control unit may control the acquisition time storage unit to perform a delay marking on a record corresponding to the received reagent identification information, and the holding time determination unit may additionally delay the extraction time including the delay marking by a predetermined time when determining whether or not a time difference between each extraction time and the current time exceeds the reagent holding time.
In the above embodiment, the low temperature environment may be a low temperature environment of-10 ℃ to-30 ℃, the low temperature reagent tag may be a low temperature resistant RFID tag, and the discrimination unit may be an RFID reader provided between the respective placement layers and configured to discriminate the RFID tag.
< example one >
The embodiment relates to an intelligent management system for non-immobilized biological reagents, which is arranged in a laboratory.
FIG. 1 is a schematic structural diagram of an intelligent management system for non-immobilized bioreagent according to an embodiment of the present invention.
As shown in fig. 1, the non-fixed type bio-reagent intelligent management system 100 includes j reagent cabinets 1, one management server 2, a plurality of laboratory technician terminals 3, one administrator terminal 4, and communication networks 5a, 5b, and 5 c.
The management server 2 is connected to each reagent cabinet 1 through a communication network 5a, to each laboratory technician terminal 3 through a communication network 5b, and to the administrator terminal 4 through a communication network 5 c. In this embodiment, the communication networks 5a, 5b, and 5c are all local area networks in a laboratory.
Fig. 2 is a schematic structural diagram of a reagent cabinet according to a first embodiment of the present invention.
As shown in fig. 2, the reagent pack 1 includes a pack body 101, a temperature adjustment unit 102, a plurality of placement layers 103 located in the pack body, a plurality of determination units 104, a pack door 105 provided in the pack body, a locking unit 106, a sensing unit 107, a recognition unit 108, a warning unit 109, and a main control chip 110.
The temperature adjustment unit 102 adjusts the temperature inside the reagent tank 1 to form a low-temperature environment suitable for storing biological reagents.
In this embodiment, the low temperature environment manufactured by the temperature adjusting portion 102 is between-10 ℃ and-30 ℃, the temperature adjusting portion 102 includes a cooling mechanism such as a compressor, a temperature setting mechanism for setting a temperature, a temperature detecting mechanism for detecting a temperature in the placing layer 103, and a control mechanism for controlling the operation of the cooling mechanism according to a temperature detection result and the set temperature so as to realize temperature control, and specific configurations and operating principles of these mechanisms are the same as those in the ultra-low temperature refrigerator in the prior art, and are not described herein again.
The placing layer 103 is provided with five layers for placing various reagent bottles. In the low-temperature reagent tank 1, a first layer accommodating layer 103a, a second layer accommodating layer 103b, a third layer accommodating layer 103c, a fourth layer accommodating layer 103d, and a fifth layer accommodating layer 103e are arranged in this order from top to bottom. Wherein, each layer of the placing layer 103 has a placing plate on which the reagent bottles are placed (the placing plate of the fifth layer of the placing layer 103e is the bottom plate of the reagent cabinet 1).
FIG. 3 is a schematic view of a reagent bottle according to a first embodiment of the present invention.
Taking the first-layer placing layer 103a as an example, as shown in fig. 3, the reagent bottles 150 can be freely placed on the placing plate 151. A reagent label 151 is attached to the cap and body of the reagent bottle 150.
In this embodiment, the reagent label 151 is a low temperature resistant RFID label that contains reagent identification information corresponding to the reagent bottle 150, and can be installed at any position of the reagent bottle 150, such as a bottle cap, a bottle body, or a bottle bottom, and can normally operate at least in a low temperature environment of-30 ℃.
The determination unit 104 is an RFID reader operable at least in a low temperature environment of-30 ℃ and is configured to determine the reagent labels 151 of all the reagent bottles 150 on the respective placement layers 103 in the reagent tank 1
In this embodiment, two determination portions 104 are provided for each placement layer 103, and as in the first placement layer 103a, the determination portions 104a-1 and 104a-2 are provided symmetrically on the left and right sides of the placement layer 103 a.
The cabinet door 105 corresponds to the reagent cabinet 1, and the laboratory technician needs to open the cabinet door 105 first to extract or return the biological reagents on each placing layer 103 of the reagent cabinet 1.
The locking portion 106 includes an electronic lock 161 provided at an edge of the cabinet door and a locker 162 provided at the door frame. The electronic lock 131 can lock and unlock the cabinet door 12 according to the control signal of the main control chip 19 under the cooperation of the lock catch 162.
The sensing part 107 is a sensor provided on the cabinet door, and can sense whether the cabinet door 105 is in a closed state.
The identification unit 108 is a door card reader for identifying a door opening card held by an experimenter.
In this embodiment, the door opening card includes identification information of an experimenter, and the identity recognition portion 108 enables the experimenter to recognize the identification information corresponding to the experimenter in the door opening card in a card swiping manner. Each experimenter has respective identification information, and the identity recognition part 108 can correspondingly judge the identity of the experimenter through the identification information.
In this embodiment, the identification information corresponds to the identity of each experimenter, that is, each experimenter has its own unique identification information, and the identity of the experimenter can be directly determined correspondingly through the identification information.
The warning part 109 is a warning lamp arranged on the front surface of the cabinet door 105, and is used for generating light flicker when receiving warning information so as to prompt staff to take or return wrong biological reagents.
Fig. 4 is a functional block diagram of a medium and low temperature reagent cabinet according to an embodiment of the present invention.
As shown in fig. 4, the main control chip 110 is electrically connected to the temperature adjustment unit 103, the determination unit 104, the locking unit 106, the sensing unit 107, the identification unit 108, and the warning unit 109, respectively, and controls operations of these components. The main control chip 110 includes a reagent tank communication unit 1101 and the main control chip 110.
The reagent tank communication unit 1101 is a communication module of the main control chip 110, and is used for performing data communication between the main control chip 110 and the management server 2.
When the identification information of the laboratory technician is identified by the identification identifying unit 108, the reagent cabinet communication unit 1101 transmits the identification information and information such as the current cabinet number of the reagent cabinet 1 to the management server 2 for processing, and when the reagent cabinet communication unit 1101 receives the door opening permission signal fed back from the management server 2, the main control chip 110 controls the locking unit 106 to unlock, so that the laboratory technician opens the cabinet door 105 to extract or return the biological reagent. In addition, when the sensing part 107 senses that the cabinet door 105 is changed from the open state to the closed state, the main control chip 110 controls the locking part 106 to lock the cabinet door.
Fig. 5 shows the contents stored in the cabinet number layer number storage unit according to the first embodiment of the present invention.
In this embodiment, in order to distinguish the reagent cabinets 1, each reagent cabinet 1 in the laboratory is provided with a cabinet number for identification. Meanwhile, in each reagent cabinet 1, the respective placing layers 103 are also provided with corresponding layer numbers in sequence, for example, the layer number of the first placing layer 103a is 1. As shown in fig. 5, the cabinet number/layer number storage unit 1102 stores the cabinet number 1103 of the current reagent kit 1, the layer number 1104 of each of the set layers 103, and the determination unit number 1105 of the determination unit 104 (i.e., the part number of the determination unit 104) corresponding to each of the layer numbers 1104, and two determination unit numbers 1105 are associated with each of the layer numbers 1104 because two determination units 104 are provided for each of the set layers 103. In practical applications, the cabinet number is the chip identification code of the main control chip 110, and the identification part number is the machine code of each identification part 104.
When the laboratory technician opens or closes the cabinet door 105 when taking out or returning the reagent, the sensing unit 107 senses the open or closed state of the cabinet door, and at this time, the main control chip 110 controls the discriminating unit 104 to discriminate the reagent discriminating information corresponding to all the reagent bottles 150 on each of the placing layers 103, and further controls the management-side communication unit 191 to transmit the discriminated reagent discriminating information, the corresponding layer number, the cabinet number, and the part number of each discriminating unit to the management server 2 after the cabinet door is locked by the control locking unit 106.
In this embodiment, since the determination unit 104 is disposed in the placement layer 103, the main control chip 110 controls the determination unit 104 to perform the determination when the sensing unit 107 senses that the cabinet door is opened and then closed again.
Fig. 6 is a block diagram of a management server according to an embodiment of the present invention.
As shown in fig. 6, the management server 2 includes a reagent-related information storage unit 201, a reagent kit information storage unit 202, a search acquisition unit 203, a comparison determination unit 204, a rough position determination unit 205, a related information update unit 206, a reagent stock determination unit 207, an expiration date determination unit 208, a discard information generation unit 209, a kit number search acquisition unit 210, an acquisition time storage unit 211, an holding time determination unit 212, a discard record storage unit 213, a usage record storage unit 214, a reagent information extraction unit 215, an identification information storage unit 216, an identity search determination unit 217, a service-side communication unit 218, and a service-side control unit 219.
FIG. 7 shows contents stored in the reagent-related information storage unit according to the first embodiment of the present invention.
As shown in fig. 7, the reagent-related information storage unit 201 stores reagent identification information 301, corresponding reagent name 302, storage temperature information 303, reagent volume 304, expiration date information 305, and reagent position information 306.
The reagent discrimination information 301 is the number information of the reagent bottle 150, and the reagent label 151 on each reagent bottle 150 contains the reagent discrimination information indicating the different number.
The reagent name 302 is a reagent name of the biological reagent contained in the reagent bottle 150.
The storage temperature information 303 is the appropriate storage temperature of the biological reagent in the reagent bottle 150.
The reagent volume 304 is the volume of biological reagent in the reagent bottle 150.
The expiration date information 305 indicates the expiration date time of the bio-reagent in the reagent bottle 150 at the corresponding location.
The reagent position information 306 includes the cabinet number of the reagent cabinet 1, the layer number of the placing layer 103, and rough position information of the reagent bottle 150 at the rough position of the placing layer 103.
In this embodiment, since the determination units 104 are symmetrically disposed on the left and right sides of each of the placement layers 103 to detect the left and right sides of the placement layer 103, respectively, and the reagent bottles 150 located in the middle of the placement layers 103 can be determined by the two determination units 104 at the same time, the rough position information corresponds to the left, middle, and right sides of the placement layers 103, and the laboratory technician can directly search for the desired biological reagents at the corresponding positions of the placement layers 103 according to the information.
As can be seen from the above figure, as the reagent position information corresponding to the reagent discrimination information P1 and P2, the case number and the layer number are the same, indicating that two reagent bottles 150 containing different reagents are stored in the same reagent storage layer 15 of the same reagent case 1, but one of the two reagent bottles 150 is on the left side of the reagent storage layer and the other is on the right side.
The reagent identification information P2, P3, and P4 correspond to the same information such as the reagent name and the reagent volume, but correspond to different reagent position information, indicating that three reagent bottles containing the same reagent are placed at different positions (the reagent bottles corresponding to P2 and P3 are placed on different placement levels 15 of the same reagent kit 1, and the reagent bottles corresponding to P4 are placed in different reagent kits 1).
The reagent position information corresponding to the reagent discrimination information P7 is a null value, indicating that the reagent bottle corresponding to the reagent discrimination information is in a state of being extracted by the laboratory technician and is not in the reagent tank 1.
In this embodiment, the cabinet number of the reagent cabinet corresponds to a unique room number, floor number, and is used to indicate the location of the reagent cabinet.
FIG. 8 shows the contents stored in the reagent kit information storage unit according to the embodiment of the present invention.
As shown in fig. 8, the reagent kit information storage unit 202 stores the kit number 311 of each reagent kit 1, the corresponding kit classification tag 312, and the environmental temperature information 313 adjusted in each reagent kit 1.
The cabinet classification label 312 contains storage and disposal labels, and the corresponding reagent cabinet for storage is used for storing reagent bottles containing biological reagents, and the corresponding reagent cabinet for disposal is used for storing discarded reagent bottles.
The environmental temperature information 313 is the operating temperature of the temperature adjustment unit 102 in each reagent pack 1 for storage, and indicates the environmental temperature of each storage layer 103 in the reagent pack 1 (the environmental temperature is-10 ℃ to-30 ℃ in this embodiment), and the environmental temperature information 313 corresponds to the storage temperature information 303.
After the laboratory technician terminal 3 lets the laboratory technician input the name of the required reagent to be searched and transmits the required reagent name and the identification information of the laboratory technician to the management server 2, the search acquisition unit 202 receives the name of the required reagent from the laboratory technician terminal 3 according to the service-side communication unit 210, searches the reagent-related information storage unit 201, and acquires the corresponding reagent position information.
In the present embodiment, after the search acquisition unit 203 acquires the reagent site information under the control of the service-side control unit 219, the service-side control unit 219 further controls the service-side communication unit 218 to transmit the searched reagent site information and the received required reagent name to the laboratory technician terminal 3 as the extraction information.
Fig. 9 is the content of the extracted information in the embodiment of the present invention.
Taking the input required reagent name SJ2 as an example, as shown in fig. 9, the extraction information 221 includes the reagent name 2211 and the corresponding reagent position information 2212. It can be seen that the reagent position information in the extraction information 221 may be multiple, and reagents representing the needs of the laboratory technician are stored at multiple positions.
When the laboratory technician takes out the reagent bottle 150 from the reagent cabinet 1 or returns the reagent bottle 150 based on the extracted information, the determination unit 104 determines the reagent in the rack layer 103 and obtains the reagent determination information for all the reagent bottles 150 in each rack layer 103 after the sensing unit 107 senses that the laboratory technician closes the cabinet door 105, and at this time, the main control chip 110 controls the reagent cabinet communication unit 1101 to transmit the reagent determination information, the determination unit number 1105, the layer number 1104, and the cabinet number 1103 corresponding to the reagent determination information to the management server 2.
When the service-side communication unit 218 receives the reagent discrimination information, the discrimination unit number, the layer number, and the cabinet number transmitted from the reagent cabinet 1, the comparison determination unit 204 compares all the received reagent discrimination information with the reagent discrimination information associated with the reagent-related information storage unit 201 based on the received layer number and cabinet number to determine missing or added reagent discrimination information.
In this embodiment, since two discrimination units 104 are provided for each of the placement layers 103, when receiving the reagent discrimination information, the comparison and determination unit 203 combines the reagent discrimination information corresponding to the same placement layer 103 and compares the combined information with the reagent discrimination information stored in the reagent-related information storage unit 201 to determine the missing or added reagent discrimination information.
When the comparison determination unit 203 determines the additional reagent determination information, the rough position determination unit 205 determines the corresponding determination unit 104 based on the part number corresponding to the additional reagent determination information, and further determines the rough position information based on the position information of the determination unit 104.
In this embodiment, two determination units 104 are provided for each placement layer 103, namely, a left determination unit corresponding to the left side of the placement layer and a right determination unit corresponding to the right side of the placement layer (for example, the setting method shown in fig. 4), and when the rough position information is set by the rough position determination unit, the rough position information is set to the left side (right side) when the rough position information is set by the left determination unit (or right determination unit), and the rough position information is set to the middle when both determination units 104 determine that the reagent bottles 150 are present.
The related information updating unit 206 updates the reagent discrimination information and the reagent position information in the reagent related information storage unit 201.
In the present embodiment, the related information update unit 206 updates the reagent related information storage unit 201 to process the reagent position information. Specifically, when the comparison determination unit 204 determines that there is missing reagent discrimination information (that is, when the plurality of pieces of reagent discrimination information stored in the reagent related information storage unit 201 include reagent discrimination information that is not included in the received reagent discrimination information and indicate that a reagent bottle is taken out from the rack), the service-side control unit 219 controls the related information update unit 206 to delete the corresponding reagent position information in the reagent related information storage unit 201 based on the missing reagent discrimination information; when the comparison determination unit 204 determines that there is increased reagent discrimination information (that is, the received plurality of pieces of reagent discrimination information include reagent discrimination information that is not included in the reagent discrimination information stored in the reagent related information storage unit 201 and indicate that a new reagent bottle is placed in the placement layer), the service-side control unit 219 controls the related information update unit 206 to add the corresponding cabinet number, layer number, and rough position information to the corresponding reagent position information in the reagent related information storage unit 201 based on the increased reagent discrimination information.
Meanwhile, in this embodiment, when receiving the reject reagent identification information transmitted from the laboratory technician terminal 3, the service-side controller 219 further controls the related information update unit 206 to delete the reagent identification information, the reagent name, and the reagent position information corresponding to the reject reagent identification information from the reagent-related information storage unit 201 based on the reject reagent identification information, and further controls the service-side communication unit 218 to return the cabinet number of the reject reagent cabinet to the corresponding laboratory technician terminal 3.
The reagent storage amount determining unit 207 is configured to determine whether or not the number of the reagent discrimination information items corresponding to the reagent name is less than a preset reagent storage number based on the reagent name corresponding to the missing reagent discrimination information after the related information updating unit 206 performs an update operation of the corresponding reagent position information in the reagent related information storage unit 201 based on the missing reagent discrimination information.
In this embodiment, the reagent holding number is preset and stored in the management server 2, and when the number of a certain type of biological reagent (i.e. the total number of reagent bottles 150 of the type of biological reagent in the reagent cabinet 1) in the laboratory is lower than the reagent holding number, it indicates that the administrator needs to purchase the biological reagent to replenish the stock. In addition, the reagent holding amount may be modified by setting by the administrator through the administrator terminal 4.
In this embodiment, since the reagent discrimination information corresponds to the reagent bottles 150 one by one, the number of the reagent discrimination information corresponding to each reagent name, that is, the number of all the biological reagents corresponding to the name, and the reagent stock amount determination section 207 can monitor the amount of the biological reagent stock in the laboratory by determining whether or not the number is less than the reagent stock amount. When the reagent stock amount determination unit 207 determines that the amount is less than the reagent stock amount, the service-side control unit 219 controls the service-side communication unit 218 to transmit a purchase presentation message including a reagent name corresponding to the missing reagent discrimination information to the administrator terminal 4.
The expiration date determination unit 208 is configured to determine whether each of the biological reagents exceeds the expiration date based on the expiration date information of each of the biological reagents and the current time in sequence.
In the present embodiment, the shelf life determination unit 29 is capable of performing a regular operation, for example, a shelf life determination of all the biological reagents every time a day, a week, or the like.
When the expiration date determination unit 29 determines that the biological reagent in a certain reagent bottle 150 has exceeded the expiration date (i.e., determines that the expiration date information corresponding to certain reagent identification information has expired), the service-side control unit 219 controls the discard information generation unit 209 to generate reagent discard information based on the reagent name and the reagent position information corresponding to the biological reagent having exceeded the expiration date, and further controls the service-side communication unit 218 to transmit the reagent discard information to the administrator terminal 4 to allow the administrator to perform discard processing.
In the present embodiment, the discard information generating unit 209 also generates reagent discard information based on the discard reagent identification information and the identification information transmitted from the laboratory technician terminal 2, and transmits the reagent discard information to the administrator terminal 4 via the service-side communication unit 218.
Further, when the administrator inputs the purchased reagent information when the purchase instruction information or the reagent discard information is received and the purchase operation is required, the service-side control unit 219 controls the related information updating unit 206 to update the reagent-related information storage unit 201 based on the purchased reagent information, and further controls the cabinet number search acquisition unit 210 to return one cabinet number to the administrator terminal 4.
The storage-cabinet-number search acquisition unit 210 searches the reagent-cabinet-information storage unit 202 based on the storage temperature information in the purchased reagent information, and acquires, as the storage cabinet number, the cabinet number of the reagent cabinet 1 whose environmental temperature information matches the storage temperature information.
In this embodiment, the environmental temperature information of each reagent cabinet 1 is a specific temperature value, the storage temperature information is a storage temperature range in which each biological reagent is suitably stored, and the cabinet number of the reagent cabinet 1 whose environmental temperature information is determined to fall within the storage temperature range is set as the cabinet number by the cabinet number retrieval and acquisition unit 210.
The acquisition time storage unit 211 records and stores the time at which the reagent is extracted by the laboratory technician, and specifically stores identification information, reagent discrimination information corresponding to the extracted reagent, the extraction time of the extracted reagent, and information on whether or not the extraction time is delayed.
In the present embodiment, the service-side control unit 219 updates the corresponding reagent position information in the reagent-related information storage unit 201 by the control-related-information updating unit 206 based on the missing reagent discrimination information determined by the comparison determination unit 204, and then controls the acquisition-time storage unit 211 to store the current time as the extraction time in association with the missing reagent discrimination information and the identification information.
The holding time determination unit 212 is configured to periodically determine whether or not the time difference between each of the extraction times stored in the acquisition time storage unit 211 and the current time exceeds the first holding time or the second holding time, based on a preset first holding time and a preset second holding time. When the extraction time is determined to be delayed, if the delay information corresponding to the extraction time is delayed, the holding time determination unit 212 determines whether the extraction time is delayed by adding the delay time to the extraction time and by determining whether the time difference between the extraction time and the current time exceeds the first holding time.
In this embodiment, the first holding time, the second holding time and the postponing time may be set as a duration of one week, fifteen days or one month according to actual conditions, wherein the second holding time should be greater than the first holding time. The holding time determination unit 212 may perform the regular determination every day, every hour, or every week.
In this embodiment, when it is determined that the first holding time has elapsed, the service-side controller 219 controls the service-side communicator 218 to transmit a deadline notification message including the extraction time and the corresponding reagent name to the corresponding laboratory technician terminal 3 based on the identification information. When it is determined that the second holding time has elapsed, the service-side control unit 219 assumes that the reagent has been held by the laboratory technician for an excessively long time, and controls the service-side communication unit 218 to transmit the expiration date reminding information and the identification information of the relevant laboratory technician to the administrator terminal 4 to allow the administrator to perform the relevant treatment.
The reject record storage unit 213 is configured to store the reject reagent identification information and the identification information in association with each other as reject information when the reject reagent identification information and the identification information are received.
In this embodiment, the discard record storage 213 is further configured to store the relevant information deleted from the reagent-related information storage 201 by the relevant information updating unit 206 according to the discard reagent identification information, so as to avoid the loss of the relevant data of the biological reagent.
The usage record storage unit 214 stores a reagent usage record including reagent identification information, a usage amount generated after each use, user identification information, and an extraction time at the time of use.
In the present embodiment, when the received reagent discrimination information, the usage amount, and the identification information are stored in association with each other, the usage amount record storage unit 214 also stores the reagent discrimination information and the extraction time corresponding to the reagent discrimination information in the acquisition time storage unit 211 in association with each other.
The reagent information extraction unit 215 is used to periodically extract a plurality of pieces of reagent discrimination information as pieces of information to be sampled from the usage record storage unit 214.
In this embodiment, the number of pieces of information to be sampled by the reagent information extracting unit 215 may be set according to actual requirements, and the extracting process of the reagent information extracting unit 215 is random extracting.
In this embodiment, after the service-side control unit 219 controls the reagent information extraction unit 215 to extract the information to be subjected to the sampling examination, the search acquisition unit 203 is also controlled to search the reagent-related information storage unit 201 based on the information to be subjected to the sampling examination to acquire the corresponding reagent name, the reagent capacity, and the reagent position information, and the service-side communication unit 218 is further controlled to transmit the information to be subjected to the sampling examination, the corresponding reagent name, the reagent capacity, and the reagent position information acquired by the search, the corresponding usage amount, the identification information, and the extraction time stored in the usage record storage unit 214 to the administrator terminal 4 as the sampling examination information.
The identification information storage unit 216 stores names, job numbers, and corresponding identification information of all the testers.
The identity search determination unit 217 searches the identification information storage unit 216 to determine whether or not the laboratory technician has the authority to open the reagent pack based on the identification information received from the reagent pack 1.
In this embodiment, when the identity search determination unit 217 determines that the identification information storage unit 216 has identification information matching the received identification information, the service-side control unit 30 controls the service-side communication unit 29 to transmit a door opening permission signal to the reagent cabinet 1, so that the reagent cabinet 1 unlocks the cabinet door and the laboratory technician opens the cabinet door.
The service-side communication unit 218 is used for performing data communication between the management server 2 and the reagent kit 1, the laboratory technician terminal 3, and the administrator terminal 4.
The service-side control unit 219 includes a control program for controlling the operations of the respective components of the management server 2.
Fig. 10 is a block diagram of the laboratory technician terminal according to the first embodiment of the present invention.
As shown in fig. 10, the laboratory terminal 3 includes a laboratory screen storage unit 301, a laboratory input display unit 302, a laboratory communication unit 303, and a laboratory control unit 304.
The experiment-side screen storage unit 301 stores a reagent request screen, an extracted information display screen, a deadline prompt screen, a delay transaction screen, and a discard transaction screen.
The reagent request screen is used for displaying when the experimenter applies for the reagent and displaying an input box in the screen to allow the experimenter to input the name of the required reagent.
In this embodiment, the reagent request screen includes a text box for allowing the experimenter to input characters, and when the experimenter inputs and confirms a character in the text box, the experimental-side communication unit 303 transmits the character as a required reagent name to the management server 2, and the search acquisition unit 203 searches the required reagent name received from the reagent-related information storage unit 201 for the corresponding reagent information, thereby further acquiring the reagent position information.
Fig. 11 is a diagram illustrating an extracted information display screen according to an embodiment of the present invention.
As shown in fig. 11, the extraction information display screen 361 is for displaying extraction information transmitted from the management server 2 when the extraction information is received, and displays the received extraction information on the screen for the experimenter to view through the reagent name display region 3611 and the reagent position information display region 2612. In addition, if the reagent position information in the extracted information is more, so that the reagent position information cannot be completely displayed in the interface, the laboratory technician can view all the contents in the extracted information through scrolling browsing in a limited picture through the scroll bar.
If the search acquisition unit 203 does not search for the corresponding reagent position information based on the required reagent name, the service-side control unit 219 controls the service-side communication unit 218 to transmit extraction information not including the required reagent name and the reagent position information to the laboratory technician terminal 3, and the extraction information display screen displays a corresponding prompt character (for example, "no corresponding search result") to notify the laboratory technician that the corresponding reagent has not been searched.
The term reminding picture is used for displaying when the term reminding information sent by the management server 2 is received and displaying the term reminding information in the picture for the experimenter to check.
In this embodiment, when the deadline prompting message is displayed on the deadline prompting screen, the corresponding reagent name and the corresponding extraction time are displayed, so that the experimenter is informed of the reagent and the time to which the experimenter should be assigned. Meanwhile, a delay handling button and a scrap handling button are displayed in the picture, so that a laboratory technician clicks and directly skips to the delay and scrap handling picture through the picture to carry out handling operation.
The postponing handling picture is used for displaying when the experimenter performs postponing handling operation and displaying an input frame in the picture so that the experimenter inputs reagent judgment information of a reagent to be postponed as postponing reagent judgment information and conducts postponing handling.
In this embodiment, when the laboratory technician confirms the delay transaction, the laboratory-side control unit 304 controls the laboratory-side communication unit 303 to transmit the delay reagent identification information input by the laboratory technician and the identification information recorded in the laboratory terminal 3 to the management server 2, and the service-side control unit 219 controls the acquisition time storage unit 211 to modify the delay information corresponding to the delay reagent identification information into the delayed time when receiving the delay reagent identification information.
The scrapping handling picture is used for displaying when a laboratory technician conducts scrapping handling operation and displaying an input frame in the picture so that the laboratory technician inputs reagent judging information of a reagent to be scrapped as scrapping reagent judging information to conduct scrapping handling.
In this embodiment, once the laboratory technician confirms the discard transaction, the laboratory-side control unit 304 controls the laboratory-side communication unit 303 to transmit the discard reagent identification information input by the laboratory technician and the identification information recorded in the laboratory technician terminal 3 to the management server 2. Meanwhile, the scrapping management picture can also display the number of the scrapping reagent cabinet sent by the management server 2, so that a laboratory technician can go to the scrapping reagent cabinet and return scrapped reagent bottles at any position of any placement layer.
The reagent amount registration screen is displayed when the laboratory technician returns the reagent and selects the registration amount operation, so that the laboratory technician inputs the reagent discrimination information of the returned reagent and the corresponding consumption amount consumed in the experiment.
In this embodiment, when the laboratory technician confirms the inputted reagent discrimination information and the usage amount, the laboratory-side communication unit 303 transmits the reagent name, the usage amount, and the corresponding identification information to the management server 2 and stores the same in the usage record storage unit 32.
The experimental side input display unit 302 is used for displaying the above-mentioned screens, so that the experimenter can complete the corresponding human-computer interaction through the screens.
The laboratory-side communication unit 303 is used to perform data interaction between the laboratory technician terminal 3 and the management server 2.
The experimental-side control unit 304 includes a computer program for controlling the operation of each component of the laboratory terminal 3.
In this embodiment, the laboratory technician terminal 3 needs to register the laboratory technicians with their respective identification information in advance and record the identification information, so that the laboratory-side communication unit 303 can transmit the identification information of the laboratory technicians to the management server 2 when communicating with the management server 2.
Fig. 12 is a block diagram of an administrator terminal according to a first embodiment of the present invention.
As shown in fig. 12, the administrator terminal 4 includes a discard information acquisition unit 401, a management-side screen storage unit 402, a management-side input display unit 403, a management-side communication unit 404, and a management-side control unit 405.
The discard information acquiring unit 401 transmits an acquisition request to the management server 2 and acquires discard information stored in the discard record storage unit 213.
The management-side screen storage unit 402 stores an operation selection screen, a deadline prompt screen, a discard reagent management screen, a prompt information display screen, a reagent information input screen, a storage-cabinet number display screen, and a sampling inspection information display screen.
The operation selection screen is used for displaying when the administrator enters the system so as to enable the administrator to select the operation required to be performed and enter the corresponding screen.
The term management screen is used for displaying the term reminding information and the corresponding identification information in the screen for the administrator to view when the term reminding information and the identification information sent by the management server 2 are received.
In this embodiment, when the deadline notification information is displayed on the deadline management screen, the corresponding reagent name, extraction time, and identification information are displayed, so as to inform the administrator of the identity of the experimenter who needs to process the deadline notification information, the extracted reagent, and the holding time.
The scrap reagent management screen is used for displaying scrap information in the screen for the administrator to view after the administrator selects scrap reagent management operation.
In this embodiment, after the administrator selects the reject reagent management operation through the operation selection screen, the management-side control unit 405 controls the reject information acquisition unit 401 to perform the acquisition operation and acquire the reject information, and then displays the acquired reject information through the reject reagent management screen. The administrator knows the using condition of the reagent in the laboratory through the scrapping information, processes the scrapped biological reagent in the scrapping reagent cabinet and judges whether to buy a new biological reagent.
The prompt information display screen is used for displaying the purchase prompt information when the purchase prompt information is received so as to enable the administrator to purchase the corresponding biological reagent.
The reagent information input screen is used for displaying when the administrator selects the reagent information entry operation, and displaying an input frame in the screen to allow the administrator to input the reagent discrimination information and the reagent name of the new reagent as the purchased reagent information.
In this embodiment, when the administrator confirms the purchased reagent information, the management-side communication unit 45 transmits the purchased reagent information to the management server 2, and the related information update unit 206 updates the purchased reagent information.
In addition, if the holding time determination unit 212 determines that the laboratory technician has not returned the reagent and has not performed any delay or discard transaction after a certain time has elapsed, the service-side communication unit 218 may also transmit a time limit reminding message to the administrator terminal 4 to remind the administrator to supervise the laboratory technician to handle the expired reagent in time.
The storage cabinet number display screen is used for displaying the storage cabinet number when the storage cabinet number is received, thereby prompting an administrator and enabling the administrator to place newly purchased biological reagents into the reagent cabinet 1 corresponding to the storage cabinet number.
The sampling inspection information display picture is used for displaying when the sampling inspection information is received, so that the sampling inspection information is displayed in the picture, and an administrator can carry out sampling inspection on the corresponding reagent according to the sampling inspection information.
In this embodiment, the spot check information displays the reagent-related information (i.e., the reagent identification information, the reagent name, the reagent capacity, and the reagent position information) of each reagent and the historical use information (i.e., the usage amount, the identification information, and the extraction time) of the reagent, so that the administrator can go to each corresponding reagent cabinet and perform spot check on the corresponding reagent, and determine whether the actual remaining capacity of the reagent matches the spot check information.
The management-side input display unit 403 is used to display the screens, so that the administrator can perform corresponding human-computer interaction through the screens.
The management-side communication unit 404 is used to perform data interaction between the administrator terminal 4 and the management server 2.
The management-side control unit 405 includes a computer program for controlling the operations of the respective components of the administrator terminal 4.
FIG. 13 is a flowchart of a reagent request process according to an embodiment of the invention.
As shown in fig. 13, the reagent extraction process of the non-immobilized biological reagent intelligent management system 100 includes the following steps:
step 1-1, the experimental side input display part 302 displays a reagent request picture to allow an experimenter to input a required reagent name, and then the step 1-2 is carried out;
step 1-2, the experimental side communication part 303 sends the required reagent name and the identification information input in step 1-1 to the management server 2, and then the step 1-3 is performed;
in step 1-3, the service-side control unit 219 controls the search acquisition unit 22 to search the reagent-related information storage unit 201 based on the required reagent name received from step 1-2 to acquire corresponding reagent location information, and then proceeds to step 1-4;
in step 1-4, the service-side control unit 219 controls the service-side communication unit 218 to send the required reagent name received in step 1-2 and the reagent location information retrieved in step 1-3 to the laboratory technician terminal 3 as extraction information, and then proceeds to step 1-5;
in step 1-5, the input display unit 38 displays the extracted information display screen and displays the extracted information received in step 1-4 on the screen for the experimenter to view, and then enters the end state.
FIG. 14 is a flow chart of a reagent extraction and return process according to an embodiment of the present invention.
As shown in fig. 14, when the laboratory technician arrives at the corresponding reagent kit 1 and performs the identification operation on the identification unit 108 to extract the reagent, or when the laboratory technician needs to return the reagent and performs the identification operation on the identification unit 108 on any one reagent kit 1, the following steps are started:
step 2-1, after the identification part 108 identifies the identification information of the experimenter, the reagent cabinet control part 1102 controls the reagent cabinet communication part 1101 to send the identification information to the management server 2 for judgment, and then the step 2-2 is carried out;
step 2-2, after receiving the door opening permission signal, the reagent cabinet control part 1102 controls the locking part 106 to unlock the cabinet door 105, so that the experimenter opens the cabinet door 105 and takes out the required biological reagent from the placing layer 103 corresponding to the extracted information, and then the step 2-3 is carried out;
step 2-3, the reagent cabinet control part 1102 controls the discrimination part 104 to perform discrimination so as to obtain the reagent discrimination information of the corresponding placement layer 103 in the reagent cabinet 1, and then the step 2-4 is performed;
step 2-4, the reagent cabinet control part 1102 controls the reagent cabinet communication part 1101 to send the reagent discrimination information corresponding to each placing layer 103, the corresponding layer number and the cabinet number of the reagent cabinet 1 discriminated in step 2-5 to the management server 2, and then the procedure goes to step 2-5;
step 2-5, the reagent retrieval control part 23 controls the comparison determination part 23 to compare the reagent discrimination information received from the step 2-4 with the reagent discrimination information stored in the reagent-related information storage part according to the cabinet number and the layer number received from the step 2-4 so as to determine missing or added reagent discrimination information, if the missing or added reagent discrimination information is determined, the step 2-6 is performed, and if the missing or added reagent discrimination information is determined not to exist, the ending state is directly performed;
in step 2-6, the service-side controller 219 controls the related information update unit 24 to update the storage information storage unit 22 with the missing or added reagent discrimination information determined in step 2-5, and then enters the end state.
Further, the laboratory technician (or the administrator) may perform the operations of returning the reagent and extracting the reagent in one reagent storage 1 at the same time, and in step 2 to step 7, the comparison determination unit 23 may determine the reagent bottles extracted and returned by the laboratory technician directly from the increase or decrease of the determination numbers of the respective layers in the reagent storage 1.
Example one action and Effect
According to the intelligent management system for the non-immobilized biological reagents provided by the embodiment, as the reagent labels are set for all biological reagents in the laboratory, and the reagents are distinguished by the distinguishing parts arranged in the reagent cabinet, once a laboratory worker extracts the biological reagents from the reagent cabinet, the related information updating parts can update the information of the corresponding biological reagents according to the reagent distinguishing information distinguished by the distinguishing parts, and therefore the management server can accurately manage the positions and the quantity of all biological reagents in the laboratory. Meanwhile, after the laboratory staff scrap the reagent and the related information updating part finishes updating, the reagent stock determining part can also determine whether the stock of the biological reagent is lower than the preset reagent stock number, so as to remind the administrator to purchase the biological reagent in time when a certain type of biological reagent needs to be supplemented in the laboratory, furthermore, after the administrator purchases the reagent, the administrator can also obtain the cabinet number of the reagent cabinet which can properly store the biological reagent according to the storage temperature information of the biological reagent through the cabinet number retrieval and acquisition part, thereby being convenient for the administrator to put the purchased biological reagent into the corresponding reagent cabinet, and when the biological reagent is put into the reagent cabinet, the administrator can also randomly put the purchased biological reagent into any position on any placement layer without worrying that the management of the biological reagent becomes disordered, thereby greatly saving the energy consumed for reagent scrap and management when purchasing in the laboratory, it also allows biological agents in the laboratory to be effectively managed.
In addition, in the first embodiment, the expiration date determination unit may determine the expiration dates of all the biological reagents in the laboratory, so that reagent discard information is automatically generated according to the information about the biological reagents when the expiration dates exceed the expiration dates, and an administrator can discard the discarded biological reagents, thereby preventing the biological reagents that have been deteriorated from being taken by the laboratory staff and causing accidents. Further, the reagent storage amount determination unit may determine the biological reagent storage amount after the administrator performs the disposal process, thereby intelligently notifying the administrator whether or not purchase of a new biological reagent is necessary.
Further, in the first embodiment, since the management server further has the rough position determination section, at the same time, at least two discrimination parts are correspondingly arranged for each placing layer of the reagent cabinet, so that for each placing layer, the approximate position of each reagent bottle can be judged according to the reagent judging information read by the judging part, the location of the reagent bottle is more clearly expressed in the reagent position information, so even if the manager randomly puts the bio-reagent into the reagent cabinet when purchasing the reagent, the experimenter can also find the required reagent in time without influencing the management of the biological reagent, and simultaneously, because the biological reagent is stored in the reagent cabinet which is refrigerated at low temperature, the laboratory technician can find the required reagent more timely, thereby effectively avoiding the loss of cold air in the reagent cabinet caused by opening the door for a long time and reducing the time of the laboratory technician in the low-temperature environment.
In the first embodiment, after the laboratory technician discards the used biological reagent, the discard information generating unit automatically generates the corresponding reagent discard information according to the discard reagent identification information to remind the administrator of the reagent discard operation. Furthermore, because the scrapping reagent cabinet is arranged, a laboratory technician can uniformly place scrapped biological reagents into the scrapping reagent cabinet, so that the scrapping treatment is convenient for an administrator. Furthermore, since the reagent cabinet for discard has the same structure as the reagent cabinet of the present invention, the laboratory technician can freely place the reagent in any position of any placement layer when returning the discarded reagent without worrying about the management confusion of the biological reagent.
In addition, in the first embodiment, when the reagent is extracted by the experimenter, the acquisition time storage unit stores the extraction time for extracting the reagent by the experimenter, and then the holding time determination unit periodically determines whether the time for holding the biological reagent by the experimenter exceeds the preset threshold value according to the extraction time, so that a corresponding prompt is generated, and the phenomenon that the biological reagent is held by the experimenter for too long time due to forgetting and the like of the experimenter, so that the taking of the biological reagent is influenced or the biological reagent is deteriorated is avoided.
Further, in the first embodiment, since the delay operation screen allows the laboratory technician to perform the delay operation procedure on the reagent, the holding time of the reagent can be extended by the procedure when the laboratory technician still needs to use the reagent.
In addition, in the first embodiment, since the determination unit for identifying the reagent label is disposed between the respective placement layers in the low-temperature environment of-10 ℃ to-30 ℃, once the laboratory technician extracts or returns the biological reagent, the determination unit can identify the reagent determination information of each biological reagent in the reagent cabinet after the cabinet door is closed, and thus the position state of the biological reagent can be counted without the intervention of the laboratory technician, and whether the reagent bottle of the biological reagent is extracted or returned by the laboratory technician can be accurately determined.
< example two >
In the second embodiment, the same reference numerals are given to the components having the same configurations as those in the first embodiment, and the description thereof will be omitted.
The second embodiment provides a low-temperature reagent cabinet capable of storing biological reagents in a low-temperature environment of-30 ℃ to-100 ℃, in which conventional electronic devices cannot work normally, and an RFID card reader and other devices cannot be set in the reagent cabinet, so that the design of the reagent cabinet in the second embodiment is different from that of the reagent cabinet in the first embodiment and the management process of corresponding reagents, and the specific differences are as follows:
fig. 15 is a schematic structural diagram of a reagent cabinet according to a second embodiment of the present invention.
As shown in fig. 15, the reagent cabinet 6 is provided with a cabinet body 101, a temperature adjusting portion 102, a placing layer 113, an identification portion 108, a warning portion 109 and a main control chip 115, and is different from the first embodiment in that the reagent cabinet 5 is provided with a thermal insulation cabinet door 111 and a layer eaves 112 protruding outward to the outside of the reagent cabinet 1 on the top portion (i.e., a placing plate of a placing layer on each placing layer 113, and a first placing layer 113a is a top plate of the whole reagent cabinet 1) corresponding to each placing layer 113, each thermal insulation cabinet door 111 is provided with a locking portion 106 and a sensing portion 107 corresponding to each placing layer 113, and the placing layers 113 are only three layers.
In addition, two discrimination parts 114 corresponding to each layer of the placing layer 113 are arranged on the layer eaves 112 corresponding to the placing layer 113 and close to the outer side surface of the insulation cabinet door 111, and are used for discriminating reagent labels of all the reagent bottles 150 in the placing layer when an experimenter opens the insulation cabinet door 111 to take out or put in biological reagents, and the reagent labels used in the second embodiment are ultra-low temperature resistant RFID labels, and can normally operate in a low-temperature environment of-100 ℃.
In this embodiment, the discrimination range of the discrimination section 114 can discriminate the entire rack layer 113 to recognize the reagent discrimination positions of all the reagent bottles in each rack layer 113. Meanwhile, in the present embodiment, the discrimination range of each discrimination section 114 is larger than one-half of the width of the placement layer 113 and smaller than the width of the placement layer 113.
Because the determination portion 114 is disposed on the layer eaves 111 (i.e. the area of the outside of the reagent cabinet 5 exposed in the normal temperature), in the second embodiment, the main control chip 115 senses that the insulation cabinet door 111 is opened in the sensing portion 107 and then controls the determination portion 114 to perform determination continuously until the sensing portion 107 senses that the insulation cabinet door 111 is closed by the experimenter, at this time, the main control chip 115 controls the reagent cabinet communication portion 1101 to send all the reagent determination information sensed by each determination portion 104 in the opening and closing process of the insulation cabinet door 111 and the corresponding determination portion number, layer number, cabinet number and identification information of the experimenter to the management server 2.
Example two actions and effects
According to the second non-fixed biological reagent intelligent management system that provides of this embodiment, compare with embodiment one, because the low temperature environment that sets up in the reagent cabinet is-30 ℃ to-100 ℃, through corresponding every layer of placing and setting up the layer eaves that outwards protrudes to set up the judgement part in the below of each layer eaves, consequently make the judgement part that is difficult to work under the low temperature can be set up in the normal atmospheric temperature, realize the discernment to placing the reagent judgement information of each biological reagent in the layer through the short time of laboratory technician when opening the cabinet door simultaneously. By the method, the non-fixed biological reagent intelligent management system of the second embodiment realizes effective and accurate management effect on all reagent bottles in the reagent cabinet at extremely low temperature.
Further, when judging the wrong reagent of returning, because the judgement portion setting of reagent cabinet is on the layer eaves in the second embodiment, consequently can discern the reagent discrimination information that the laboratory technician put into more rapidly, at this moment, thereby the management server also can accomplish more rapidly and judge so that warning portion reminds the laboratory technician to put into wrong reagent more in time to avoid the laboratory technician to take place the influence that the mistake caused biological reagent of returning better. And to the reagent cabinet in the embodiment one, because the temperature is higher relatively, can not lead to the fact the effect of freezing more fast to biological reagent, consequently remind the laboratory technician relatively more slowly can not cause biological reagent's loss.
In addition, in the second embodiment, since the outwardly protruding layer eaves are provided for each of the placement layers and the determination part is provided below each layer eaves in the low-temperature environment of-30 ℃ to-100 ℃, the determination part that is difficult to operate at an excessively low temperature can be provided at a normal temperature, and the identification of the reagent discrimination information of each biological reagent in the placement layer is realized in a short time when the laboratory technician opens the cabinet door. By the method, the non-fixed biological reagent intelligent management system realizes effective and accurate management effect on all reagent bottles in the reagent cabinet at extremely low temperature.
< example three >
In the third embodiment, the same reference numerals are given to the components having the same configurations as those in the first and second embodiments, and the description thereof will be omitted.
The third embodiment provides a biological reagent intelligent management system for uniformly managing a normal temperature reagent cabinet and low temperature reagent cabinets with different temperatures, wherein the normal temperature reagent cabinet, the low temperature reagent cabinet with a temperature of-30 ℃ and the scrapped reagent cabinet all adopt the same structure (adjusted to be normal temperature or low temperature by the temperature adjusting part 102) as the reagent cabinet 1 in the first embodiment, and the low temperature reagent cabinet with a temperature of-30 ℃ to-100 ℃ adopts the structure of the reagent cabinet 6 in the second embodiment.
FIG. 16 is a schematic diagram showing the configuration of an intelligent non-immobilized bioreagent management system according to a third embodiment of the present invention.
As shown in fig. 16, the management server 7 is communicatively connected to each of the normal temperature reagent tank, the low temperature reagent tank, and the disposal reagent tank via the communication network 5a, to each of the user terminals 3 via the communication network 5b, and to the administrator terminal via the communication network 5 c.
The management server 7 includes a return reagent verification determination unit in addition to having the same configuration as the management server 1 in the first embodiment.
The returned reagent verification determination unit is configured to verify the returned biological reagent based on the reagent discrimination information received from the reagent tank and the tank number of the reagent tank, and determine whether the biological reagent is loaded into the wrong reagent tank.
In this embodiment, the reagent discrimination information corresponding to the returned biological reagent is the added reagent discrimination information determined by the comparison determination section 203, and therefore, the returned reagent verification determination section determines whether the biological reagent is returned to the wrong reagent cabinet according to the added reagent discrimination information and the corresponding cabinet number.
In the present embodiment, the reagent-related information storage unit 201 further stores a storage temperature range corresponding to the reagent identification information, and the temperature adjustment unit 102 of each reagent tank stores current temperature information corresponding to a currently adjusted temperature. When the reagent tank communication unit 1101 transmits the reagent discrimination information discriminated by the discrimination unit 104 to the management server 7, the current temperature information is also transmitted to the management server 7 at the same time.
Further, the return reagent verification determination unit determines whether the returned biological reagent is placed in the wrong reagent tank, based on whether the received current temperature information is within the storage temperature range corresponding to the missing reagent discrimination information, when the returned biological reagent is verified. If the current temperature information exceeds the storage temperature range, the biological reagent is wrongly put into a reagent cabinet with an improper storage temperature by a laboratory technician. At this time, the management-side control unit 211 controls the management-side communication unit 210 to transmit an erroneous reagent placement signal to the corresponding reagent tank, and causes the alarm unit 109 to activate an alarm to notify the laboratory technician of the erroneously placed biological reagent.
Example three actions and effects
According to the third non-fixed biological reagent intelligent management system provided by the embodiment, because the normal-temperature reagent cabinet and the low-temperature reagent cabinet are arranged in a laboratory in a mixed manner, when a laboratory returns a reagent, whether the biological reagent returned by the laboratory is placed in a wrong reagent cabinet or not can be judged by the return reagent auditing and judging part, and warning reminding is performed by the warning part of the reagent cabinet, so that the problem that the biological reagent is damaged and lost due to the fact that the storage temperature of the biological reagent is not consistent with the actual temperature in the reagent cabinet is avoided, and the problem that the laboratory returns the wrong biological reagent in the reagent cabinet due to the reasons such as errors (for example, small reagents are different due to the similar colors) is avoided.
The above-described embodiments are merely illustrative of specific embodiments of the present invention, and the present invention is not limited to the description of the above-described embodiments.
For example, in the above embodiment, the reagents corresponding to the reagent discrimination information included in the extracted information are all extracted by the experimenter, however, in another aspect of the present invention, the experimenter may acquire only the reagents corresponding to part of the extracted information. At this time, the extracted information display screen further has a reagent selecting portion. Specifically, when the same reagent name in the reagent-related information storage unit has a plurality of corresponding reagent identification information, the extracted information includes a plurality of reagent identification information, and after the extracted information is sent to the laboratory technician terminal, the extracted information display screen displays each reagent name and corresponding reagent position information in the extracted information on the reagent selecting part, so that the laboratory technician selects one or more reagents to view in detail, and at the moment, the extracted information display screen displays the reagent position information corresponding to the selection of the laboratory technician. Therefore, the intelligent management system for the non-immobilized biological reagent can allow an experimenter to selectively extract the reagent.
For example, in the first embodiment, two symmetrically arranged determination portions are provided for each placement layer, and the rough position information is the left side and the right side corresponding to the positions of the determination portions, respectively. In other aspects of the invention, each placing layer can be correspondingly provided with more RFID readers and is uniformly arranged in the placing layer, and the number of corresponding rough positions is further increased, so that the rough position information is more accurate, and the position of the reagent bottle on the placing layer can be more accurately judged.
In addition, in the second embodiment, two determination portions are provided on the layer eaves corresponding to each layer of the placement layer, and the range of the determination portions can cover the entire placement layer. In other schemes of the invention, in order to facilitate the discrimination part to discriminate the whole placement layer, a form of a directional RFID reader can be adopted, the directional RFID reader is installed slightly obliquely outward, i.e. the reading direction of the directional RFID reader faces inward, and meanwhile, an inward inclined slope part can be arranged on the layer brim at the position of the RFID reader, so that electromagnetic waves of the RFID reader enter the placement layer to read the sample label on the biological sample in the placement layer.
Further, when in actual use, more discrimination parts can be correspondingly arranged under each layer of eave according to actual requirements, so that the accuracy of discrimination of rough position information is improved.
For another example, in the reagent kit according to the second embodiment, the reagent discrimination information recognized by the judgment section is the reagent discrimination information of all the biological reagents in the entire rack, and the management server judges the missing or added reagent discrimination information by the comparison judgment section. However, in another embodiment of the present invention, the determination unit provided on the layer eaves may directly identify the reagent extracted or returned by the laboratory technician, and in this case, the determination unit may determine that the reagent passes through the layer eaves when the laboratory technician takes out (or returns) the reagent from (or to) the placement layer, in which case the determination unit may identify the corresponding reagent determination information, and further transmit the reagent determination information to the management server, and the management server may determine whether the reagent is extracted or placed in the original reagent-related information storage unit based on whether the reagent determination information is stored in the original reagent-related information storage unit.
In another embodiment of the present invention, the normal temperature reagent cabinet and the low temperature reagent cabinet mixed in the third embodiment may both have the reagent cabinet structure of the second embodiment. At this moment, all reagent cabinets can realize going on more fast that biological reagent puts into wrong warning to avoid the experimenter to the influence that biological reagent caused when taking place to return the mistake better.
For example, in the embodiment, the criterion that the return reagent verification determination unit determines that the biological reagent is returned incorrectly is the temperature of the reagent tank and the storage temperature range of the biological reagent. However, in another embodiment of the present invention, the cabinet classification information stored in the reagent cabinet information storage unit may be further subdivided, for example, the classification may be performed according to the type of the biological reagent, and in this case, when the return reagent audit determination unit determines whether or not the biological reagent is placed in the wrong reagent cabinet, the biological reagent may be audited according to the reagent name (or other attribute information) corresponding to the biological reagent and the cabinet classification information of the reagent cabinet.
For example, in the above-described embodiment, the reagent-related information storage unit stores only the reagent discrimination information, the reagent name, and the reagent position information. However, in actual use, the reagent-related information storage unit can also store information such as reagent specifications and use needs, and record various types of attribute information of the biological reagent in the reagent bottle.
For example, in the above embodiment, the warning portion is a warning lamp provided on the front surface of the cabinet door. In another aspect of the present invention, the warning unit may be a sound-light alarm, a display, or another device having a presentation effect, and may be provided at a position on the reagent tank where the warning unit is easily viewed.
For example, in the above embodiment, the cabinet classification label only includes storage and disposal, and in actual use, the cabinet classification label may further include more classifications, so that the reagent cabinets can be classified according to the function or storage condition of the reagent, and the reagent is stored in the corresponding reagent cabinet according to different cabinet classification labels.

Claims (10)

1. An intelligent non-immobilized bioreagent management system for an administrator to manage bioreagent in a laboratory, comprising:
at least one reagent cabinet for storing the biological reagent requiring a low temperature environment or a normal temperature environment;
a plurality of laboratory staff terminals respectively held by laboratory staff having different identification information;
an administrator terminal held by an administrator who manages the reagent; and
the management server is respectively in communication connection with the reagent cabinet, the laboratory technician terminal and the administrator terminal,
wherein the reagent cabinet comprises a cabinet body, a temperature adjusting part which is positioned in the cabinet body and used for generating the low-temperature environment or the normal-temperature environment, a plurality of placing layers which are positioned in the cabinet body and used for bearing reagent bottles with reagent labels containing reagent identification information, a plurality of identification parts which are respectively arranged corresponding to the placing layers and used for reading the reagent labels, a cabinet door arranged on the cabinet body, a locking part used for locking the cabinet door, an induction part used for inducing the opening and closing state of the cabinet door, an identity identification part used for identifying the identification information of the experimenter, a reagent cabinet communication part and a reagent cabinet control part,
the laboratory terminal comprises a laboratory side picture storage part, a laboratory side input display part and a laboratory side communication part,
the administrator terminal includes an administration-side screen storage section and an administration-side input display section,
the management server includes a reagent-related information storage unit, a reagent tank information storage unit, a search acquisition unit, a related information update unit, a reagent storage amount determination unit, a tank number search acquisition unit, a service-side communication unit, and a service-side control unit,
the reagent-related information storage unit stores at least a reagent name of each of the biological reagents, storage temperature information indicating a required temperature at the time of storing the biological reagent, and corresponding reagent position information including a reagent cabinet number in which the reagent bottle is located and a layer number of a layer in which the reagent bottle is located,
the reagent cabinet information storage unit stores the cabinet number of each reagent cabinet and the ambient temperature information in the corresponding reagent cabinet adjusted by the temperature adjustment unit,
the experimental side picture storage part also stores a scrapped handling picture,
the management side picture storage part stores a prompt information display picture and a purchase reagent information input picture,
when the identification information is recognized by the identification recognition unit, the reagent kit control unit controls the reagent kit communication unit to transmit the identification information to the management server for determination, and controls the lock unit to unlock the door and allow the laboratory technician to open the cabinet door and extract the desired biological reagent from the storage layer when receiving a door opening permission signal fed back from the management server,
once the sensing part senses that the cabinet door is opened, the reagent cabinet control part controls the judging part to judge so as to obtain the reagent judging information of the corresponding placing layer, and further controls the reagent cabinet communication part to correspondingly send the reagent judging information obtained by judging, the layer number of the corresponding placing layer and the cabinet number of the reagent cabinet to the management server,
the service-side control unit controls the relevant information update unit to update the reagent-related information storage unit based on the received reagent position information,
once the laboratory technician uses up the biological reagent and needs to perform the abandonment handling procedure, the experimental side input display part displays the abandonment handling picture and allows the laboratory technician to input the reagent judgment information of the biological reagent to be abandoned as the abandonment reagent judgment information so as to perform the abandonment handling,
the lab-side communication unit transmits the reject reagent identification information and the identification information to the management server when the laboratory worker confirms the reject transaction,
the service-side control unit controls the related information update unit to update the reagent-related information storage unit based on the received reject reagent discrimination information, controls the reagent stock determination unit to determine whether or not the amount of the biological reagent is less than a predetermined reagent stock amount based on the received reagent discrimination information,
upon determining that the reagent holding amount is lower than the predetermined reagent holding amount, the service-side control section controls the service-side communication section to transmit a purchase instruction message including a reagent name corresponding to the received reagent position information to the administrator terminal,
the management-side input display unit displays the prompt information display screen and displays the purchase prompt information in the prompt information display screen to prompt the administrator to purchase a corresponding biological reagent, and further displays the purchased reagent information input screen after the administrator purchases the biological reagent so that the administrator inputs purchased reagent information including at least a reagent name of the purchased biological reagent and stored temperature information and transmits the purchased reagent information to the management server,
the service-side control unit controls the relevant information update unit to update the reagent-related information storage unit based on the purchased reagent information, controls the storage-cabinet number search acquisition unit to search the reagent-cabinet information storage unit based on the storage temperature information in the purchased reagent information, acquires the cabinet number of the reagent cabinet whose ambient temperature information matches the storage temperature information as a storage-cabinet number, and further controls the service-side communication unit to return the storage-cabinet number to the administrator terminal,
the management-side input display unit displays the rack number on the rack number display screen so that the administrator places the purchased biological reagent in an arbitrary position on an arbitrary placement layer of the reagent tank corresponding to the rack number.
2. The intelligent non-immobilized bioreagent management system of claim 1 wherein:
wherein the management server further comprises a quality-guarantee period determination unit and a discard information generation unit,
the management side picture storage part also stores a scrap information display picture,
the reagent-related information storage unit also stores shelf life information of each of the biological reagents,
the service-side control unit periodically controls the shelf life determination unit to sequentially determine whether or not each of the biological reagents exceeds the shelf life based on the shelf life information and the current time,
when the expiration date judging part judges that the biological reagent exceeds the expiration date, the service-side control part controls the discard information generating part to generate reagent discard information based on the reagent name and the reagent position information corresponding to the biological reagent exceeding the expiration date, and controls the service-side communication part to transmit the reagent discard information to the administrator terminal,
and the management side input display part displays the scrap information display screen and displays the reagent scrap information in the scrap information display screen so that the administrator can scrap the corresponding biological reagent and purchase the corresponding biological reagent.
3. The intelligent non-immobilized bioreagent management system of claim 1 wherein:
wherein the low-temperature environment is an ultralow-temperature environment with the temperature of-30 ℃ to-100 ℃,
the reagent label is an RFID label adapting to the ultralow temperature environment,
the reagent cabinet is also provided with layer eaves which respectively extend outwards from the top of each placing layer to the outside of the reagent cabinet,
the cabinet doors are a plurality of heat preservation cabinet doors respectively corresponding to the placing layers,
the distinguishing part is an RFID reader used for identifying the RFID label and is arranged on the position, close to the outer side surface of the heat-insulating cabinet door, on the layer eave.
4. The intelligent non-immobilized bioreagent management system of claim 3 wherein:
wherein the management server further includes a rough position determination section,
the reagent position information further includes rough position information corresponding to a rough position of the reagent bottle on the placement layer,
at least two discrimination parts with different part numbers are arranged below each layer eave,
when the reagent cabinet communication part sends the reagent identification information obtained by identification to the management server in correspondence with the layer number of the corresponding placing layer and the cabinet number of the low-temperature reagent cabinet, the part number of the corresponding identification part is also sent to the management server,
when the management server receives the reagent discrimination information, the part number, the layer number, and the cabinet number transmitted from the low-temperature reagent cabinet, the service-side control unit further controls the rough position determination unit to determine the rough position information corresponding to the reagent discrimination information based on the reagent discrimination information and the part number.
5. The intelligent non-immobilized bioreagent management system of claim 4 wherein:
wherein the experiment side image storage unit further stores a reagent request image and an extraction information display image,
the laboratory side input display unit displays the reagent request screen to allow the laboratory technician to input the name of the biological reagent to be extracted as the name of the required reagent,
the lab-side communication unit transmits the required reagent name to the management server upon confirmation of the required reagent name by the experimenter,
the service-side control unit controls the search acquisition unit to search the reagent-related information storage unit based on the required reagent name and acquire the corresponding reagent position information, and further controls the service-side communication unit to send the reagent position information and the required reagent name to the laboratory technician terminal as extracted information,
the experimental side input display part displays the extraction information display picture and displays the received extraction information in the picture, so that the experimenter can go to the corresponding reagent cabinet according to the extraction information and search and extract the required biological reagent at the rough position on the corresponding placing layer.
6. The intelligent non-immobilized bioreagent management system of claim 1 wherein:
wherein the management server further comprises a discard information generation unit,
the service side control part controls the scrapped reagent generation part to generate reagent scrapped information according to the scrapped reagent discrimination information and the identification information, and controls the service side communication part to send the reagent scrapped information to the administrator terminal,
and the management side input display part displays the scrap information display screen and displays the reagent scrap information in the scrap information display screen so that the administrator can scrap the corresponding biological reagent and purchase the corresponding biological reagent.
7. The intelligent non-immobilized bioreagent management system of claim 6 further comprising:
a scrapped reagent cabinet used for storing scrapped biological reagents which are used up by the laboratory staff and scrapped,
wherein the reagent cabinet information storage part is also stored with the cabinet number of the scrapped reagent cabinet,
when the service-side control unit controls the reject information generation unit to generate the reagent reject information, the service-side control unit further controls the reject record storage unit to store the received reject reagent identification information and the identification information in association with each other, and further controls the service-side communication unit to send the unit number of the reagent unit for rejection back to the corresponding laboratory technician terminal,
the experimental side input display part further displays the cabinet number of the scrapped reagent cabinet in the scrapped handling picture so that the laboratory technician returns the scrapped biological reagent to any position on any placing layer of the scrapped reagent cabinet.
8. The intelligent non-immobilized bioreagent management system of claim 1 wherein:
wherein the management server further comprises an acquisition time storage unit and a holding time determination unit,
the experimental side picture storage part also stores a time limit reminding picture,
the service-side control unit controls the acquisition time storage unit to store the current time as the extraction time in association with the received reagent discrimination information and the identification information when the relevant information update unit updates the reagent-related information storage unit based on the received reagent position information,
the holding time determination unit periodically determines whether or not a time difference between each of the extraction times and the current time exceeds the reagent holding time or the limited holding time based on a preset reagent holding time and a limited holding time,
when the reagent holding time is judged to have elapsed, the service-side control section controls the service-side communication section to transmit a deadline notification message including the extraction time to the corresponding laboratory technician terminal based on the identification information,
the experimental side input display part displays the time limit reminding picture and displays the time limit reminding information in the picture to remind the experimenter,
the service-side control section controls the service-side communication section to transmit the term reminding information and the identification information to the administrator terminal upon determining that the limited holding time has elapsed,
the management-side input display unit displays the term management screen, and displays the term reminder information and the identification information on the screen for the administrator to perform processing.
9. The intelligent non-immobilized bioreagent management system of claim 8 wherein:
wherein the experiment side picture storage part also stores a delay transaction picture,
once the experimenter needs to carry out delay handling procedures, the experimental side input display part displays the delay handling picture to let the experimenter input the reagent identification information of the reagent to be delayed and carry out delay handling,
the lab-side communication unit transmits the input reagent discrimination information and the identification information to the management server when the experimenter confirms the deferred transaction,
the service-side control unit controls the acquisition time storage unit to mark a record corresponding to the received reagent discrimination information for a delay,
when the holding time determination unit determines whether or not the time difference between each of the extraction times and the current time exceeds the reagent holding time, the extraction time including the delay flag is additionally delayed by a predetermined time at the time of determination.
10. The intelligent non-immobilized bioreagent management system of claim 1 wherein:
wherein the low-temperature environment is a low-temperature environment of-10 ℃ to-30 ℃,
the low-temperature reagent label is a low-temperature resistant RFID label,
the discrimination unit is an RFID reader provided between the respective placement layers and configured to discriminate the RFID tag.
CN202011623800.0A 2020-01-10 2020-12-31 Non-fixed biological reagent intelligent management system Pending CN113191464A (en)

Applications Claiming Priority (2)

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CN2020100260729 2020-01-10

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Country Link
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