CN113011808A - Intelligent management method for immobilized high-value antibody reagent - Google Patents
Intelligent management method for immobilized high-value antibody reagent Download PDFInfo
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Abstract
The invention provides a high-value antibody reagent intelligent management method capable of effectively managing high-value antibody reagents in a laboratory, which is characterized by comprising the following steps of: step S1, storing reagent related information; step S2, inputting the name of the required reagent; step S3, sending to an auditor for auditing, and entering step S4 if the auditing is passed; step S4, retrieving and acquiring reagent position information corresponding to the required reagent name; step S5, sending the retrieved information as extraction information to the experimenter, so that the experimenter can go to a corresponding reagent cabinet; step S6, judging whether to unlock the cabinet door according to the identification information of the experimenter so as to enable the experimenter to extract the reagent, and entering step S7 if judging to unlock the cabinet door; step S7, acquiring corresponding missing reagent position information after the sensor senses that the reagent tube in the corresponding fixed groove is taken out; in step S8, the corresponding reagent position information in the reagent-related information is updated based on the missing reagent position information.
Description
Technical Field
The invention relates to an intelligent management method for an immobilized high-value antibody reagent.
Background
Antibody reagents refer to proteins having protective effects produced by the body due to stimulation by antigens, and generally have certain effects in the prevention, diagnosis and treatment of diseases. However, the true effect of the antibody is often determined by preliminary screening, confirmation, and the like, which are performed to determine the lease of the antibody by examination and examination. However, the antibody reagent has the characteristics of small dosage and high value, and if the antibody reagent is improperly stored, abused, accidentally damaged and the like due to poor management, the antibody reagent causes great cost loss. Therefore, the antibody reagents need to be strictly managed in the laboratory.
At present, reagent management in a laboratory generally adopts strict management on extraction behaviors of laboratory workers, so that operation processes of reagent warehousing and export, reagent taking, reagent use and the like of related personnel are completely monitored. Or the administrator manages the behavior records of the experimenters, so that the statistics and the control of the reagent information are completed.
However, the above management method does not provide good management for the antibody reagent, and the antibody reagent is usually purchased by a special purchasing person and placed in a reagent cabinet, but the experimenter cannot know in which reagent cabinet the required antibody reagent is specifically placed. Even if it is specified in advance which reagent cabinet various kinds of antibody reagents are stored in, since tens or hundreds of antibody reagents can be stored in one reagent cabinet, it is still troublesome for the experimenter to find the reagent cabinet, and the work efficiency of the experimenter is affected.
Disclosure of Invention
In order to solve the problems, the invention provides an intelligent management method of an immobilized high-value antibody reagent, which can effectively manage the high-value antibody reagent in a laboratory, and adopts the following technical scheme:
the invention provides an intelligent management method for fixed high-value antibody reagents, which is characterized by being used for managing the high-value antibody reagents fixedly placed in fixed grooves of a plurality of placing layers in at least one reagent cabinet in a laboratory, and comprising the following steps: step S1, storing the reagent name of each high-value antibody reagent and the corresponding reagent position information including the cabinet number of the reagent cabinet where the high-value antibody reagent is located, the layer number of the placing layer where the high-value antibody reagent is located and the groove number of the fixed groove where the high-value antibody reagent is located as the relevant reagent information respectively; step S2, displaying a reagent name input picture through an input display module to allow a laboratory technician to input the name of the high-value antibody reagent to be extracted as a required reagent name; step S3, the name of the required reagent and the identification information of the experimenter are sent to an auditor to enable the auditor to conduct auditing, and if the auditor passes the auditing, the step S4 is carried out; step S4, a retrieval acquisition module is adopted to retrieve the relevant information of the reagent according to the name of the required reagent and acquire the corresponding reagent position information; step S5, the name of the required reagent and the retrieved reagent position information are used as extraction information to be sent to an experimenter, so that the experimenter can go to a corresponding reagent cabinet and identify the identification information of the experimenter through an identification module arranged on the reagent cabinet; step S6, adopting an identity judgment module to judge whether to enable a locking module arranged in the reagent cabinet to release the cabinet door of the reagent cabinet or not according to the identification information so as to enable a laboratory technician to open the cabinet door and extract the reagent in a corresponding fixed groove, and entering step S7 if the cabinet door is judged to be unlocked; step S7, after the sensors arranged in the fixed grooves sense that the reagent tubes in the corresponding fixed grooves are taken out, acquiring the groove numbers corresponding to the sensors, the layer numbers of the corresponding placing layers and the cabinet numbers of the corresponding reagent cabinets as missing reagent position information; in step S8, the relevant information updating module is used to update the corresponding reagent position information in the reagent relevant information according to the missing reagent position information.
Action and Effect of the invention
According to the intelligent management method for the fixed high-value antibody reagent, the reagent names and the reagent position information of all reagents in a river laboratory are stored as the relevant reagent information, so that the positions of corresponding antibody reagents can be directly retrieved from the relevant reagent information according to the required reagent names input by a laboratory technician, and meanwhile, when the required reagent names are input by the laboratory technician, the required reagent names of the laboratory technician are audited through the auditor to limit and standardize the laboratory technician to extract only the required high-value antibody reagents. In addition, because fixed slot and reagent pipe one-to-one, consequently the laboratory technician can obtain required reagent according to reagent positional information accurately in the fixed slot on the layer of placing of corresponding reagent cabinet, after extracting reagent, further updates reagent relevant information according to the response of the sensor in the corresponding fixed slot, has realized carrying out accurate management to every reagent through reagent storage location, has simplified the storage data when guaranteeing strict management and control. Through the intelligent management method for the high-value antibody reagent, the extraction process of the high-value antibody reagent in a laboratory is optimized, and meanwhile, automatic and real-time monitoring and effective management of the high-value antibody reagent are realized, so that the high-value antibody reagent is really used in a real place, and accidental loss of the antibody reagent is avoided.
Drawings
FIG. 1 is a schematic diagram of a system for implementing a high-value antibody reagent intelligent management method according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a reagent cabinet according to a first embodiment of the present invention;
FIG. 3 is a schematic diagram illustrating the placement of reagent vessels according to one embodiment of the present invention;
FIG. 4 is a functional block diagram of a reagent cabinet according to a first embodiment of the present invention;
FIG. 5 is a table of contents stored in the bin number layer number storage unit according to an embodiment of the present invention;
FIG. 6 is a flowchart of a method for intelligently managing immobilized high-value antibody reagents according to one embodiment of the present invention;
FIG. 7 is a table of contents of reagent-related information in accordance with an embodiment of the present invention;
FIG. 8 is a diagram illustrating the content of the extracted information according to the first embodiment of the present invention;
FIG. 9 is a flowchart of an audit extraction step according to an embodiment of the present invention; and
FIG. 10 is a flow chart of the reagent selection step in example two of the present invention.
Detailed Description
Hereinafter, the intelligent management method of the immobilized high-value antibody reagent according to the present invention will be described in detail with reference to the drawings.
In one aspect, the present invention provides an intelligent management method for immobilized high-value antibody reagents, which is used for managing high-value antibody reagents immobilized in fixed slots of a plurality of deposition layers in at least one reagent cabinet in a laboratory, the intelligent management method comprising the steps of: step S1, storing the reagent name of each high-value antibody reagent and the corresponding reagent position information including the cabinet number of the reagent cabinet where the high-value antibody reagent is located, the layer number of the placing layer where the high-value antibody reagent is located and the groove number of the fixed groove where the high-value antibody reagent is located as the relevant reagent information respectively; step S2, displaying a reagent name input picture through an input display module to allow a laboratory technician to input the name of the high-value antibody reagent to be extracted as a required reagent name; step S3, the name of the required reagent and the identification information of the experimenter are sent to an auditor to enable the auditor to conduct auditing, and if the auditor passes the auditing, the step S4 is carried out; step S4, a retrieval acquisition module is adopted to retrieve the relevant information of the reagent according to the name of the required reagent and acquire the corresponding reagent position information; step S5, the name of the required reagent and the retrieved reagent position information are used as extraction information to be sent to an experimenter, so that the experimenter can go to a corresponding reagent cabinet and identify the identification information of the experimenter through an identification module arranged on the reagent cabinet; step S6, adopting an identity judgment module to judge whether to enable a locking module arranged in the reagent cabinet to release the cabinet door of the reagent cabinet or not according to the identification information so as to enable a laboratory technician to open the cabinet door and extract the reagent in a corresponding fixed groove, and entering step S7 if the cabinet door is judged to be unlocked; step S7, after the sensors arranged in the fixed grooves sense that the reagent tubes in the corresponding fixed grooves are taken out, acquiring the groove numbers corresponding to the sensors, the layer numbers of the corresponding placing layers and the cabinet numbers of the corresponding reagent cabinets as missing reagent position information; in step S8, the relevant information updating module is used to update the corresponding reagent position information in the reagent relevant information according to the missing reagent position information.
In the above-described embodiment, the identification information may be door opening information in a door opening card held by a laboratory technician, a password, two-dimensional code information corresponding to the identity of the laboratory technician, fingerprint information of the laboratory technician, face information, iris information, or voiceprint information, and the identification information of all laboratory technicians in the laboratory is stored as information related to the laboratory technician, and the step S6 may include the following sub-steps: s6-1, searching relevant information of the experimenter by adopting an identity judgment module according to the received identification information and judging whether consistent identification information exists, and if so, entering S6-2; and step S6-2, sending a door opening permission signal to the reagent cabinet so as to enable the locking module to unlock the cabinet door.
In the above embodiment, the method may further include the following extraction and review steps: step T1, storing the missing reagent position information and the identification information as extraction record information; step T2, adopting a reagent extraction auditing module to audit whether the extracted information is consistent with the corresponding record in the extracted record information according to the identification information, and entering step T3 if the audit is inconsistent; step T3, a warning is initiated using a warning module disposed within the reagent cabinet to alert the laboratory technician that the wrong high value antibody reagent has been extracted.
In the above embodiment, the present invention may further include a technical feature that the search acquisition unit searches for a plurality of pieces of reagent site information, and the method further includes a reagent extracting step of: and step R1, displaying the reagent selection part by extracting the information display picture and displaying all the reagent position information in the extracted information in the picture so as to enable the experimenter to select one or more reagent information to be extracted, and step R2, storing the reagent information to be extracted as the extracted information and the identification information of the corresponding experimenter as the request record information.
In the above embodiment, the step S6 may further include the following steps: step S6-1, the identity judgment module is adopted to search the request record information according to the received identification information and the cabinet number and judge whether the matched identification information and the cabinet number exist, if so, the step S6-2 is executed; and step S6-2, sending a door opening permission signal to the reagent cabinet so as to enable the locking module to unlock the cabinet door.
< example one >
FIG. 1 is a schematic diagram of a system for implementing an intelligent management method for high-value antibody reagents in an embodiment of the present invention.
As shown in fig. 1, the intelligent management method for high-value antibody reagents of the present embodiment is implemented based on a system 100, where the system 100 includes at least one reagent cabinet 1, a management server 2, at least one experimenter terminal 3, an auditor terminal 4, and communication networks 5a, 5b, and 5 c.
The reagent cabinet 1 is used to store high-value antibody reagents that will be used by the laboratory.
The management server 2 is respectively connected with each reagent cabinet 1 through a communication network 5a, is respectively connected with each laboratory technician terminal 3 through a communication network 5b, and is connected with the auditor terminal 4 through a communication network 5 c. In this embodiment, the communication networks 5a, 5b, and 5c are all local area networks in a laboratory.
The experimenter terminals 3 are terminals such as smart phones, computers and tablet computers, are respectively held by different experimenters and perform related operations, and identification information corresponding to the respective experimenters is stored in each experimenter terminal 3.
The auditor terminal 4 is held by an auditor and is used for approving the reagent request information of the experimenter.
Fig. 2 is a schematic structural diagram of a reagent cabinet according to a first embodiment of the present invention.
As shown in fig. 2, the reagent kit 1 includes a kit body 11, a kit door 12 provided on the kit body, a locking portion 13, a sensing portion 14, five placement layers 15 located in the kit body, a plurality of sensors 16 provided in the placement layers 15, an identification portion 17, a warning portion 18, and a main control chip 19.
The locking portion 13 comprises an electronic lock 131 arranged at the edge of the cabinet door and a catch (not shown) arranged on the door frame. The electronic lock 131 can lock and unlock the cabinet door 12 according to the control signal of the main control chip 19 under the cooperation of the lock 132.
The sensing part 14 is a sensor disposed on the cabinet door 12, and is used for sensing the opening and closing of the cabinet door and generating a corresponding sensing signal.
The placing layer 15 is provided with five layers for placing various reagent tubes. In the reagent cabinet 1, a first layer containing layer 15a, a second layer containing layer 15b, a third layer containing layer 15c, a fourth layer containing layer 15d and a fifth layer containing layer 15e are arranged from top to bottom in sequence. Wherein, each layer of the placing layer 15 has a placing plate, and the reagent tube is fixed on the placing plate (the placing plate of the fifth layer of the placing layer 15e is the bottom plate of the reagent cabinet 1).
FIG. 3 is a schematic diagram illustrating a placement state of a reagent cartridge according to a first embodiment of the present invention.
Taking the first layer-placing layer 15a as an example, as shown in fig. 3, the placing plate 153 is provided with a plurality of fixing grooves 151 for holding the reagent vessels 152, and each fixing groove 151 can fix one reagent vessel 152.
The plurality of sensors 16 are disposed in the respective fixing grooves 151 in one-to-one correspondence, and sense and determine whether or not the reagent vessels 152 are placed in the fixing grooves 151.
In this embodiment, each of the fixing slots 151 has a respective slot number, and the information sensed by the sensor 16 corresponds to the slot number of the respective fixing slot 151.
The identification part 17 is a door card reading device for identifying a door opening card held by an experimenter.
In this embodiment, the door opening card contains identification information of the experimenter, and the experimenter can make the identity recognition portion 17 recognize the identification information of the experimenter in a card swiping mode. The identification information corresponds to the identity of each experimenter, namely each experimenter has the unique identification information thereof, and the identity of the experimenter can be directly and correspondingly judged through the identification information.
The warning part 18 is a warning lamp arranged on the front surface of the cabinet door 12 and is used for generating light flicker when receiving warning information sent by the main control chip 19 so as to prompt staff to take wrong reagents.
Fig. 4 is a functional block diagram of a reagent cabinet according to a first embodiment of the present invention.
As shown in fig. 4, the main control chip 19 is in communication connection with the locking portion 13, the sensing portion 14, the sensors 16 (k sensors are corresponding to each layer 15), the identification portion 17, and the warning portion 18, respectively, for controlling the operations of these components. The main control chip 19 includes a reagent tank communication unit 191 and a tank number slot number storage unit 192.
The reagent tank communication unit 191 is a communication module connected to the main control chip 19, and is used for performing data communication between the reagent tank 1 and the management server 2.
When the identification information of the laboratory technician is identified by the identification identifying unit 17, the reagent cabinet communication unit 191 sends the identification information and information such as the current cabinet number of the reagent cabinet 1 to the management server 2 for processing, and only when the door opening permission signal fed back from the management server 2 is received, the main control chip 19 controls the locking unit 13 to unlock, thereby allowing the laboratory technician to open the cabinet door 12 to extract or return the reagent.
Fig. 5 is a table of contents stored in the cabinet number layer number storage unit according to the first embodiment of the present invention.
In this embodiment, in order to distinguish the reagent cabinets 1, each reagent cabinet 1 in the laboratory is provided with a cabinet number for identification. Meanwhile, in each reagent cabinet 1, the respective placing layer 15 and the fixing groove 151 on the placing layer 15 are also provided with the corresponding layer number and groove number in sequence, for example, the groove number of the first fixing groove 151 on the placing layer 15a of the first layer is 1, the groove number of the second fixing groove 151 is 2, and so on. Taking the reagent kit with the number GH1 as an example, as shown in fig. 5, the kit number 1921 of the current reagent kit 1, the layer number 1922 of each set layer 15, the groove number 1923 of each fixed groove 151 in each set layer 15, and the sensor number 1924 of the sensor 16 corresponding to each groove number 1923 one by one are stored in the kit number groove number storage unit 192 of the reagent kit GH 1. In practical applications, the cabinet number is the chip identification code of the main control chip 19, and the sensor number is the machine code of each sensor 16.
When the laboratory technician takes out the high-value antibody reagent, the sensor 16 senses that a certain reagent tube 152 is taken out, and the main control chip 19 acquires the corresponding layer number 1992 and the slot number 1993 from the cabinet number and slot number storage section 192 according to the sensor number of the sensor, and transmits the layer number 1992 and the slot number 1993 together with the cabinet number 1991 of the current reagent cabinet 1 as the missing reagent position information to the management server 2.
In this embodiment, when the experimenter takes out the high-value antibody reagent to close the cabinet door 12, the sensing part 14 senses that the cabinet door 12 is closed, and the main control chip 19 controls the locking part 13 to lock the cabinet door 12.
FIG. 6 is a flowchart of a method for intelligently managing immobilized high-value antibody reagents according to an embodiment of the present invention.
As shown in fig. 6, the intelligent management method for high-value antibody reagents according to this embodiment is implemented based on the system 100 including the reagent cabinet 1, the management server 2, the laboratory technician terminal 3, the auditor terminal 4, and the communication network 5, and specifically includes the following reagent extraction steps:
in step S1, the reagent name of each high-value antibody reagent in the laboratory and the reagent position information indicating the position of the reagent tube 152 containing the corresponding high-value antibody reagent are stored as reagent-related information.
FIG. 7 is a table of contents of reagent-related information in accordance with an embodiment of the present invention.
As shown in fig. 7, the reagent-related information 21 stores the following information: reagent name 211 and reagent location information 212. Specifically, the method comprises the following steps:
the reagent name 211 is the reagent name of the high value antibody reagent contained in the reagent tube 152.
The reagent position information 212 includes a cabinet number of the reagent cabinet, a layer number of the placement layer, and a groove number of the fixing groove, and indicates a position where the reagent tube 152 is located.
In this embodiment, since only one reagent tube 152 can be placed in one fixing groove 151, each piece of reagent position information 213 stored in the reagent-related information storage unit 21 uniquely corresponds to one reagent tube 152.
As can be seen from FIG. 7, the reagent names 211 corresponding to the different reagent site information 213 may be the same, for example, the reagent names corresponding to the reagent site information GH1-1-3, GH1-1-4, GH2-3-1 and GH2-4-1 are all the same, indicating that the reagent tubes 152 at these sites contain the same high value antibody reagent.
In this embodiment, the reagent related information such as the reagent name and the reagent position information of each reagent tube 152 is input by a relevant person (e.g., a reagent purchaser) when purchasing a reagent and placing the reagent in the reagent cabinet.
Meanwhile, in step S1 of the present embodiment, the identification information of all the laboratory workers in the laboratory is also stored as the information relating to the laboratory workers at the same time.
In this embodiment, the reagent-related information and the laboratory technician-related information are stored in one management server 2, and the management server 2 is connected to each reagent cabinet 1 through a communication network, thereby completing the management of the reagent tubes 152.
In step S2, the input display module displays a reagent name input screen to allow the laboratory technician to input the name of the high-value antibody reagent to be extracted as the required reagent name.
In this embodiment, the reagent name input screen is displayed by an input display module of the laboratory technician terminal 3 (for example, a terminal device such as a computer or a smartphone) held by the laboratory technician, and the input display module is a display device (for example, a display, a touch panel, or the like) and an input device (for example, a keyboard, a touch panel, or the like) of the laboratory technician terminal 3. The reagent name input screen displays a text box for the laboratory technician to input characters, and after the laboratory technician inputs and confirms characters in the text box through an input display module (for example, a keyboard or the like) of the laboratory technician terminal 3, the laboratory technician terminal 3 transmits the characters to the management server 2 as the required reagent name and the identification information of the laboratory technician, and the process proceeds to step S3.
And step S3, sending the name of the required reagent and the identification information of the experimenter to an auditor to allow the auditor to perform auditing, and entering step S4 if the auditor passes the auditing.
In step S3 of this embodiment, the management server 2 sends the received required reagent name and the identification information as to-be-audited information to an auditor terminal 4 (e.g., a computer, a smartphone, or other terminal device) held by an auditor, at this time, the auditor terminal 4 displays the to-be-audited information through a corresponding display device (e.g., a display) to allow the auditor to audit whether to repeat extracting a reagent corresponding to the required reagent name from an experimenter corresponding to the identification information, if the audit is passed, the auditor terminal 4 sends an audit-passed information to the management server 2 to enter step S4, and if the audit is not passed, the auditor terminal 4 sends an audit-denied information to the management server 2 and forwards the audit-passed information to the corresponding experimenter terminal 3 to notify the experimenter.
In this embodiment, the identification information of the experimenter includes identity information (for example, information such as name) and an identity number (for example, information such as job number and ID) of the experimenter, and the examiner can confirm the identity of the experimenter through the identification information.
And step S4, retrieving the relevant information of the reagent according to the required reagent name input in the step S2 by adopting a retrieval and acquisition module and acquiring the corresponding reagent position information.
In this embodiment, the retrieval and acquisition module is a computer program stored in the management server 2, and is configured to retrieve a consistent reagent name from the relevant reagent information stored in the management server 2 according to the required reagent name, and further acquire corresponding reagent location information.
In step S5, the name of the required reagent and the retrieved reagent position information are transmitted to the laboratory technician as the extraction information, and the laboratory technician goes to the corresponding reagent kit 1, and then the flow proceeds to step S6 when the laboratory technician recognizes the identification information of the laboratory technician by the recognition module (i.e., the recognition unit 17) provided in the reagent kit 1.
Fig. 8 shows the content of the extracted information according to the first embodiment of the present invention.
Taking the input required reagent name SJ2 as an example, as shown in fig. 8, the extraction information 221 includes the reagent name 2211 and the corresponding reagent position information 2212. It can be seen that the reagent position information in the extraction information 221 may be multiple, and reagents representing the needs of the laboratory technician are stored at multiple positions. In this embodiment, the reagent position information in the extracted information may be multiple, and reagents representing the needs of the experimenter are stored in multiple positions.
In this embodiment, the management server 2 sends the extraction information to the laboratory technician terminal 3, so that the laboratory technician obtains the search result of the name of the required reagent. When the laboratory technician terminal 3 receives the reagent position information, the extraction information display screen is displayed through the display device, and the required reagent name and all the received reagent position information are displayed in the screen, so that the laboratory technician goes to the corresponding reagent cabinet 1 according to the reagent position information and obtains the reagent tube 152 in the corresponding fixing groove 151 of the corresponding placing layer 15.
In step S6, the identity determination module determines whether or not to unlock the door 12 of the reagent kit 1 by the locking module (i.e., the locking unit 13) disposed in the reagent kit 1 based on the identification information, so that the laboratory technician opens the door 12 and extracts the reagent from the corresponding fixing groove 151, and if it is determined that the door is unlocked, the process proceeds to step S7.
In this embodiment, the identity determination module is a computer program provided in the management server 2. When the identification information is determined, the identity determination module retrieves the identification information of all the experimenters stored in the management server 2 according to the identification information, if the matched identification information is retrieved, a door opening permission signal is sent to the reagent cabinet 1, and the locking part 13 releases the locking of the cabinet door so as to enable the experimenters to open the cabinet door.
After the laboratory technician opens the cabinet door 12, the corresponding placing layer 15 is found according to the reagent position information, and the required high-value antibody reagent is taken out according to the number of the fixed groove.
In this embodiment, step S6 includes the following sub-steps:
and step S6-1, searching relevant information of the experimenter according to the received identification information by adopting an identity judgment module, judging whether consistent identification information exists, if so, entering step S6-2, and if not, entering step S6-3.
Step S6-2, a door opening permission signal is sent to the reagent cabinet 1 to let the locking module unlock the cabinet door.
In step S6-3, a determination failure message is sent to the reagent kit 1, so that the warning module (i.e., the warning unit 18) provided in the reagent kit 1 issues a warning of the identification error.
Step S7, after the sensor 16 disposed in each fixing groove 151 senses that the reagent tube 152 in the corresponding fixing groove 151 is taken out, acquiring the groove number corresponding to the sensor 16, the layer number of the corresponding placing layer 15, and the cabinet number of the corresponding reagent cabinet 1 as the missing reagent position information;
in this embodiment, when the sensor 16 senses that the reagent tube 152 in the corresponding fixing groove 151 is removed, the determination signal containing the number of the sensor 16 is sent to the main control chip 19, and the main control chip 19 determines the position information corresponding to the extracted reagent according to the number of the sensor 16 and uses the position information as the missing reagent position information.
In step S8, the relevant information updating module is used to update the corresponding reagent position information in the reagent relevant information according to the missing reagent position information.
In this embodiment, the related information updating module is configured to update the reagent related information stored in the management server 2, and when the management server 2 receives the missing reagent location information, the related information updating module deletes the corresponding reagent location information in the reagent related information according to the missing reagent location information, so that the high-value antibody reagent at the location is taken out from the reagent cabinet 1.
In this embodiment, the laboratory technician may extract a plurality of reagents after opening the cabinet door, and at this time, a plurality of sensors 16 generate responses in step S7, so as to generate a plurality of missing reagent position information and process the missing reagent position information in the subsequent steps.
FIG. 9 is a flowchart of an audit extraction step according to an embodiment of the present invention.
As shown in fig. 9, the intelligent management method for high-value antibody reagents further includes the following steps of:
in step T1, the missing reagent position information and the identification information are stored as extraction record information in association with each other.
In this embodiment, the extraction verification step occurs after the sensor 16 recognizes that the reagent tube 152 is extracted (i.e., after step S7), and the extraction verification step is performed each time the laboratory technician takes out one reagent tube 152.
And step T2, adopting a reagent extraction and verification module to verify whether the extracted information is consistent with the corresponding record in the request record information or not according to the identification information, and entering step T3 if the verification is inconsistent.
In step T3, a warning is activated by the warning module (i.e., the warning unit 18) provided in the reagent kit 1 to thereby warn the laboratory technician that an incorrect high-value antibody reagent has been extracted.
In the above step T3, once the warning module issues a warning, the warning is stopped only after the experimenter replaces the reagent tube 152 with the wrong extraction in the original fixing slot (i.e. the sensor senses that the reagent tube 152 is returned, a sensing signal is sent to the main control chip 19, and the main control chip 19 sends a stop signal to the warning module when the same result as the result of the previous sensing of the missing is determined), at this time, the experimenter may extract the reagent again and perform the steps S7 and later.
< example two >
In the second embodiment, the same flow as that in the first embodiment is denoted by the same reference numerals, and the description thereof is omitted.
FIG. 10 is a flow chart of the reagent selection step in example two of the present invention.
Step S5 of the second embodiment further includes the following reagent extracting step shown in fig. 10:
step R1, displaying the reagent selection part by extracting the information display picture and displaying all the reagent position information in the extracted information in the picture so as to enable the experimenter to select one or more reagent information to be extracted;
and step R2, storing the information of the reagent to be extracted as extraction information and the identification information of the corresponding experimenter as request record information.
In the second embodiment, the specific sub-step of step S6 is different from the sub-step of step S6 in the first embodiment. In this embodiment, step S6 includes the following steps:
step S6-1a, the identity judging module is adopted to search the request record information according to the received identification information and the cabinet number and judge whether the matched identification information and the cabinet number exist, if so, the step S6-2a is carried out;
and step S6-2a, sending a door opening permission signal to the reagent cabinet so as to enable the locking module to unlock the door of the reagent cabinet.
Examples effects and effects
According to the intelligent management method for the fixed high-value antibody reagent, the reagent names and the reagent position information of all reagents in a laboratory are stored as the relevant reagent information, so that the positions of the corresponding antibody reagents can be directly retrieved from the relevant reagent information according to the required reagent names input by a laboratory technician, and meanwhile, when the required reagent names are input by the laboratory technician, the required reagent names of the laboratory technician are audited through the auditor to limit and standardize the laboratory technician to extract only the required high-value antibody reagents. In addition, because fixed slot and reagent pipe one-to-one, consequently the laboratory technician can obtain required reagent according to reagent positional information accurately in the fixed slot on the layer of placing of corresponding reagent cabinet, after extracting reagent, further updates reagent relevant information according to the response of the sensor in the corresponding fixed slot, has realized carrying out accurate management to every reagent through reagent storage location, has simplified the storage data when guaranteeing strict management and control. Through the intelligent management method for the high-value antibody reagent, the extraction process of the high-value antibody reagent in a laboratory is optimized, and meanwhile, automatic and real-time monitoring and effective management of the high-value antibody reagent are realized, so that the high-value antibody reagent is really used in a real place, and accidental loss of the antibody reagent is avoided.
In addition, in the first embodiment, because the identification information of the laboratory staff is judged through the identity judgment module, only when the personnel who open the reagent cabinet door is the laboratory staff registered in the laboratory, the cabinet door can be opened, and therefore the situation that the cabinet door is opened by an unknown person is avoided. The identification mode of the experimenter can be set according to actual requirements, for example, the identification of the experimenter information is completed through the door opening information and the password in the door opening card held by the experimenter, the two-dimensional code information corresponding to the identity of the experimenter, the fingerprint information, the face information, the iris information or the voiceprint information of the experimenter.
In addition, in the first embodiment, whether the extracted information and the corresponding identification information are consistent with the extracted record information is checked through the extraction and verification step, so that whether a laboratory technician mistakenly extracts other reagents when extracting the reagents from the reagent cabinet is effectively judged, and the warning module of the reagent cabinet is used for reminding the laboratory technician, so that the serious problems that the laboratory result is wrong due to the reagent extraction error of the laboratory technician and the like are solved, and the problem that the reagent management in a laboratory is disordered due to the mistaken extraction of the laboratory technician is also solved.
In addition, in the first embodiment, because the identity determination module retrieves and determines the corresponding request record in the request record storage part according to the identification information and the cabinet number received from the reagent cabinet, the function of extracting the antibody reagent can be completed only after the experimenter applies for the antibody reagent in advance is realized, so that the high-value antibody reagent is further strictly controlled, and the management effect is improved.
In addition, in the second embodiment, since the extraction information display screen further includes the reagent selection portion, the laboratory technician can autonomously select a desired reagent (for example, select an antibody reagent in a reagent kit close to the laboratory technician, or select the same or a reagent kit close to the laboratory technician when it is necessary to extract a plurality of types of reagents). Simultaneously, still take notes the reagent information of waiting to extract that the laboratory technician selected to realized the control to laboratory technician's request information, and can carry out reagent cabinet's identity through this request information and judge the operation, thereby produced and let only need carry out the laboratory technician who extracts the reagent and just can open the effect of reagent cabinet in the laboratory, provide the protection to the antibody reagent of high-value in the laboratory better.
The above-described embodiments are merely illustrative of specific embodiments of the present invention, and the present invention is not limited to the description of the above-described embodiments.
For example, in step S1 of the second embodiment, the storage of the laboratory technician information may not be performed. In other schemes of the invention, whether the cabinet door is unlocked can be judged by combining the experimenter information and the request record information.
For example, in the above embodiment, the warning portion is a warning light disposed on the front surface of the cabinet door. In another aspect of the present invention, the warning unit may be an audible and visual alarm or other device having a prompt effect, and may be disposed at a position where the reagent tank is easily viewed or where sound is easily emitted, as required.
For example, after the warning is triggered in step T3 of the above embodiment, the warning is activated only by the warning section to thereby remind the laboratory technician that an erroneous high-value antibody reagent has been extracted. However, in other embodiments of the present invention, after the step T3 triggers the warning, it is also possible to send a warning about the error to a relevant person (e.g. an administrator) or to record, so as to perform a stricter management.
Claims (5)
1. An intelligent management method for fixed high-value antibody reagents is used for managing the high-value antibody reagents fixedly placed in fixed grooves of a plurality of placing layers in at least one reagent cabinet in a laboratory, and comprises the following steps:
step S1, storing the reagent name of each high-value antibody reagent and the corresponding reagent position information including the cabinet number of the reagent cabinet where the high-value antibody reagent is located, the layer number of the placing layer where the high-value antibody reagent is located and the groove number of the fixed groove where the high-value antibody reagent is located as the relevant reagent information respectively;
step S2, displaying a reagent name input picture through an input display module to allow a laboratory technician to input the name of the high-value antibody reagent to be extracted as a required reagent name;
step S3, sending the name of the required reagent and the identification information of the experimenter to an auditor to enable the auditor to perform auditing, and entering step S4 if the auditor passes the auditing;
step S4, a retrieval acquisition module is adopted to retrieve the relevant information of the reagent according to the required reagent name and acquire corresponding reagent position information;
step S5, sending the required reagent name and the retrieved reagent position information as extraction information to the experimenter, so that the experimenter can go to the corresponding reagent cabinet and identify the identification information of the experimenter through an identification module arranged on the reagent cabinet;
step S6, an identity determination module is adopted to determine whether a locking module arranged in the reagent cabinet is allowed to unlock the cabinet door of the reagent cabinet according to the identification information so as to allow the laboratory technician to open the cabinet door and extract the reagent in the corresponding fixed slot, and if the cabinet door is determined to be unlocked, the step S7 is carried out;
step S7, after the sensors arranged in the fixed grooves sense that the reagent tubes in the corresponding fixed grooves are taken out, acquiring the groove numbers corresponding to the sensors, the layer numbers of the corresponding placing layers and the cabinet numbers of the corresponding reagent cabinets as missing reagent position information;
and step S8, updating the corresponding reagent position information in the reagent related information according to the missing reagent position information by using a related information updating module.
2. The intelligent management method for immobilized high-value antibody reagents according to claim 1, characterized in that:
wherein the identification information is door opening information, a password, two-dimensional code information corresponding to the identity of the experimenter, fingerprint information, face information, iris information or voiceprint information of the experimenter in a door opening card held by the experimenter,
identification information of all the laboratory workers in the laboratory is stored as information on the laboratory workers,
the step S6 includes the following sub-steps:
step S6-1, an identity judgment module is adopted to retrieve the relevant information of the experimenter according to the received identification information and judge whether consistent identification information exists, if so, the step S6-2 is executed;
and step S6-2, sending a door opening permission signal to the reagent cabinet so as to enable the locking module to unlock the cabinet door.
3. The intelligent management method for the fixed high-value antibody reagent according to claim 1, characterized by further comprising the following steps of extracting and auditing:
a step T1 of storing the missing reagent position information and the identification information in association with each other as extraction record information;
step T2, adopting a reagent extraction auditing module to audit whether the extracted information is consistent with the corresponding record in the extracted record information according to the identification information, and entering step T3 if the audit is inconsistent;
step T3, a warning is initiated using a warning module disposed within the reagent cabinet to alert the laboratory technician that an incorrect high value antibody reagent has been extracted.
4. The intelligent management method for immobilized high-value antibody reagents according to claim 1, wherein the search acquisition unit searches for a plurality of pieces of reagent position information, further comprising the following reagent selection step:
a step R1 of displaying a reagent selection part by extracting an information display screen and displaying all the reagent position information in the extracted information in the screen so as to allow the experimenter to select one or more as to-be-extracted reagent information,
and step R2, storing the information of the reagent to be extracted as extraction information and the identification information of the corresponding experimenter as request record information.
5. The intelligent management method for immobilized high-value antibody reagents according to claim 4, characterized in that:
wherein the step S6 further includes the following steps:
step S6-1, an identity judgment module is adopted to search the request record information according to the received identification information and the cabinet number and judge whether the identification information and the cabinet number which are matched exist, if yes, the step S6-2 is executed;
and step S6-2, sending a door opening permission signal to the reagent cabinet so as to enable the locking module to unlock the cabinet door.
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