CN113144016A - Medicine for treating rhinitis and preparation process thereof - Google Patents

Abstract

The invention relates to the important technical field, in particular to a medicine for treating rhinitis and a preparation process thereof, the rhinitis medicine provided by the invention is prepared into powder by Chinese herbal medicine components, different medicines are pretreated and then ground into particles for standby, the particles are stirred according to the preparation proportion to obtain a finished product, the finished product is treated in a nasal cavity by a spray can, the medicine is taken for 1-2 times per week according to symptoms, the medicine frequency is greatly reduced, the medicine is prepared by pure Chinese herbal medicines, the treatment cost of a patient is reduced under the condition of not influencing the medicine effect, the medicine is prepared by Chinese herbal medicines, no side effect is produced when the medicine is used, and the medicine can be used safely.

Description

Medicine for treating rhinitis and preparation process thereof

Technical Field

The invention relates to the important technical field, in particular to a medicine for treating rhinitis and a preparation process thereof.

Background

Rhinitis, an inflammatory disease of the nasal cavity, is inflammation of the mucous membrane of the nasal cavity caused by viruses, bacteria, allergens, various physicochemical factors and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of the nasal mucosa. The rhinitis is complicated and diversified in constitutional reasons, generally divided into hereditary, viral infection, allergic infection and the like, slight rhinitis has little influence on work and life of people, but serious rhinitis can cause severe consequences such as migraine, dizziness and complications and the like, the rhinitis is not easy to eradicate in treatment in slight or serious conditions, continuous medication is needed, and great inconvenience is brought to life of people.

At present, most of rhinitis medicines in the market are prepared into rhinitis tablets by a Chinese-western combined pharmaceutical method, the rhinitis tablets are taken orally for treatment, the number of the rhinitis tablets is limited during use, the purpose of eradicating the rhinitis cannot be achieved, patients need to take the rhinitis tablets for a long time to relieve discomfort of the patients, the rhinitis tablets can generate resistance to the medicines after being taken for a long time, and the efficacy of the rhinitis tablets is gradually reduced.

Disclosure of Invention

The invention aims to overcome the defects that the existing medicine can not eradicate rhinitis and needs to be taken frequently for a long time, and provides a medicine for treating the rhinitis with low use frequency and small irritation and a preparation process thereof.

The invention is realized by the following technical scheme: the medicine for treating rhinitis comprises, by weight, 6-15 parts of magnolia flower, 5-15 parts of asarum, 10-25 parts of pedicellus melo, 1-6 parts of ligusticum wallichii, 0.5-3 parts of borneol, 3-15 parts of centipeda minima, 2-9 parts of rhizoma coptidis, 5-16 parts of mint, 2-8 parts of radix angelicae, 2-8 parts of loofah flesh and 0.5-5 parts of artificial musk.

Furthermore, the medicine for treating rhinitis comprises the following raw materials, by weight, 8-12 parts of magnolia flower, 6-10 parts of asarum, 12-20 parts of muskmelon pedicel, 2-5 parts of ligusticum wallichii, 1-3 parts of borneol, 5-10 parts of centipeda minima, 4-8 parts of coptis chinensis, 8-12 parts of mint, 3-6 parts of radix angelicae, 3-6 parts of vegetable sponge and 1-3 parts of artificial musk.

Furthermore, the medicine for treating rhinitis comprises the following raw materials, by weight, 9 parts of magnolia flower, 9 parts of asarum, 15 parts of muskmelon pedicel, 3 parts of ligusticum wallichii, 3 parts of borneol, 9 parts of centipeda minima, 5 parts of coptis chinensis, 9 parts of mint, 4 parts of radix angelicae, 5 parts of vegetable sponge and 2 parts of artificial musk.

Further, the preparation process of the rhinitis medicine comprises the following steps: step 1: preparing medicinal materials, namely cleaning flos magnoliae, asarum, muskmelon pedicel, ligusticum wallichii, borneol, centipeda minima, goldthread root, mint, radix angelicae, loofah sponge and artificial musk, removing dirt and drying in the shade;

step 2: soaking rhizoma Ligustici Chuanxiong in rice wine for pretreatment, the pretreatment method comprises: cleaning rhizoma Ligustici Chuanxiong, drying in the shade, sealing in rice wine, soaking in the shade at normal temperature for 1-5 days, and exciting the property of rhizoma Ligustici Chuanxiong with rice wine;

and step 3: parching flos Magnoliae in casserole at 30-50 deg.C for 30-60 min until the surface of flos Magnoliae turns yellow, grinding, and sieving with 200 mesh sieve;

and 4, step 4: calcining radix Angelicae Dahuricae and Coptidis rhizoma, grinding, and sieving with 200 mesh sieve;

and 5: sterilizing herba asari, pedicellus melo, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, herba Centipedae, herba Menthae, fructus Luffae, and artificial Moschus in a steamer for 3-5 hr, parching the different herbs separately, grinding, and sieving with 200 mesh sieve;

step 6: and (3) proportioning the standby materials obtained in the steps 1-5, uniformly stirring and preparing into powder.

The using method comprises the following steps: the powder taking device comprises a spraying pot, wherein the spraying pot is used for taking 0.05-0.15g of powder each time, the spraying pot is stretched into a nasal cavity for spraying, the powdery medicinal powder is sprayed into the nasal cavity, the spraying pot comprises an air bag, a medicine taking short pipe is arranged at an air outlet of the air bag, the powder is sprayed into the nasal cavity through air bag compression after the medicine is filled by the medicine taking short pipe, the medicine is sprayed to a focus of a patient, goose does not eat and magnolia flower is warm in nature and plays a role in dispelling wind and cold, corydalis tuber, mint and coptis borneol are cold in nature and cool in nature, the effects of dispelling wind and heat and clearing and detoxifying are played, loofah and angelica dahurica play a role in diminishing inflammation and easing pain, the patient takes 0.1g +/-0.05 g each time every time, the dosage is properly adjusted according to the disease duration of the patient and the tolerance to the medicine, and spicy food, tobacco, wine and other strong irritant articles are fast during the medicine taking period.

The invention has the beneficial effects that: the Chinese herbal medicine powder is prepared by Chinese herbal medicine components, different medicines are pretreated and then ground into particles for standby, the particles are stirred according to a preparation ratio to obtain a finished product, the medicine is used in a nasal cavity through a spray can for 1-2 times per week according to symptoms, the medicine frequency is greatly reduced, the medicine is prepared by pure Chinese herbal medicines, the treatment cost of a patient is reduced under the condition that the medicine effect is not influenced, the Chinese herbal medicines are prepared, no side effect is caused during use, the medicine cannot be depended on, and the medicine can be used safely.

Detailed Description

Mint: it is pungent and cool, and has effects of removing toxic substance, inducing perspiration, dispelling pathogenic wind, and removing heat when entering lung and liver channels.

Centipeda minima: it is pungent and warm in flavor and enters lung and liver meridians. The efficacy is as follows: disperse wind-cold, sores, abscess and toxic swelling.

And (3) magnolia flower: pungent and warm in flavor, enter lung and stomach meridians. The efficacy is as follows: unblocking lung and inducing resuscitation, and dispelling wind-cold. The medicine is essential for treating headache, nasal obstruction, bad smell and frequent thick nasal discharge.

Asarum: also called asarum, asarum simsii, etc., belonging to the order of aristolochiales, aristolochiaceae, perennial herbs; the rootstock is upright or transverse, and has a plurality of fibrous roots; 2 leaves are usually in heart shape or egg shape, and the flower is purple black; the flower stalk is 2-100 px long; the flower envelope has a triangular, oval shape, approximately spherical shape, a diameter of about 37.5px, and a brownish yellow color. The flowering period is 4-5 months. Has the functions of expelling wind, dispelling cold, promoting diuresis, inducing resuscitation, etc. It is commonly used for wind-cold headache, nasosinusitis, toothache, phlegm-fluid cough, wind-damp arthralgia, etc. The asarum can not only externally disperse wind-cold, but also internally dispel yin-cold, and has better effects of relieving pain and cough;

ligusticum wallichii: the surface is gray brown or brown, rough and wrinkled, and has a plurality of parallel raised wheel nodes, a concave round-like stem mark at the top end, and a plurality of small nodular root marks on the lower side and the wheel nodes. Firm, hard to break, yellow-white or gray-yellow cross section, dispersed with yellow-brown oil chamber, forming a wavy lamellar ring. Fragrant smell, bitter and pungent taste, slightly numb tongue and slightly sweet.

Muskmelon pedicel: pungent, cold and bitter. It enters heart and spleen meridians. The functions are as follows: clearing away heat and toxic materials, and eliminating carbuncle and swelling, and can be used for treating sore throat, furuncle, sore pain, carbuncle, cellulitis, carbuncle on the back, nephritis, parotitis, and other pyogenic infections.

And (3) yellow lotus: it is bitter in taste and cold in nature and enters the large intestine meridian of heart, gallbladder, stomach. The efficacy is as follows: clearing heat and drying dampness, purging pathogenic fire and removing toxicity, mainly treating the symptoms of the dampness and heat, blood heat, conjunctival congestion, toothache, diabetes, carbuncle, swelling and sore, eczema and ear canal purulence.

Borneol: pungent and bitter in flavor, cool in nature, and entering heart and lung meridians. The efficacy is as follows: unblocking orifices, dispelling stagnated fire, removing nebula, improving eyesight, relieving swelling and alleviating pain. The main treatment is as follows: coma due to febrile disease, fright epilepsy, phlegm coma, qi block, deafness, aphtha, otitis media, carbuncle and swelling, hemorrhoid, etc.

Radix angelicae: white, warm in nature, pungent and slightly bitter in taste, has the effects of dispelling wind and eliminating dampness, dredging orifices and relieving pain, and reducing swelling and expelling pus, is widely used for treating diseases such as cold headache, eyebrow prism pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, abscess and the like in clinic, and has better curative effect.

Vegetable sponge: also called luffa mesh, luffa shell, luffa vegetable sponge, luffa pulp, luffa thread, luffa tendon, luffa vegetable sponge, serrate club moss, is the vascular bundle in the mature fruit of the annual herb luffa belonging to the cucurbitaceae family or the withered fruit of luffa. The towel gourd is a common vegetable in summer and autumn in China, is produced in most provinces in China, is a cultivation product, and has good quality for Jiangsu and Zhejiang. The loofah sponge contains xylan, mannan, galactan and the like, the decoction has obvious effects of easing pain, calming and resisting inflammation, and clinical researches show that the loofah sponge has certain curative effects on treating acute mastitis, herpes zoster around eyes, thyroid adenoma and the like by oral administration and external application

Artificial musk: the artificial musk is a fragrant and warm medicine for inducing resuscitation, has the functions of inducing resuscitation and refreshing mind, promoting blood circulation and removing stasis, and inducing parturition and removing fetuses, and has the effects of invigorating heart and spleen channels. The function is as follows: 1. it has strong actions of inducing resuscitation and unblocking, so it is indicated for coma and convulsion due to invasion of warm disease heat into pericardium, and convulsions and phlegm syncope due to apoplexy. 2. It can move blood system and has the actions of promoting blood circulation and resolving hard mass, and relieving swelling and pain, and is often combined with toxicity-removing and blood-activating herbs, and used for sores and furuncles with internal or external application.

Example 1

Preparing raw materials: taking 6g of biond magnolia flower, 5g of asarum, 10g of muskmelon pedicel, 1g of ligusticum wallichii, 0.5g of borneol, 3g of centipeda minima, 2g of rhizoma coptidis, 5g of mint, 2g of angelica dahurica, 2g of luffa pulp and 0.5g of artificial musk;

cleaning rhizoma Ligustici Chuanxiong, drying in the shade, soaking in rice wine for 0.5-2 days, taking out, drying in the shade again, parching in casserole for 1-2 hr to remove water in the herbs, parching, grinding, and sieving with 200 mesh sieve; parching flos Magnoliae in marmite at 50 deg.C for 50 min, stopping parching after the villi on flos Magnoliae surface falls off and turns yellow, parching to dry, grinding, and sieving with 200 mesh sieve;

calcining radix Angelicae Dahuricae and Coptidis rhizoma, grinding, and sieving with 200 mesh sieve;

sterilizing herba asari, pedicellus melo, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, herba Centipedae, herba Menthae, fructus Luffae, and artificial Moschus in a steamer for 4 hr, parching the different herbs separately, grinding, and sieving with 200 mesh sieve;

uniformly stirring the prepared medicinal powder, adding the asarum, the muskmelon pedicel, the ligusticum wallichii, the borneol, the centipeda minima, the mint, the vegetable sponge and the artificial musk into a stirrer, uniformly stirring, adding the magnolia flower and the asarum, stirring again, finally adding the angelica dahurica and the coptis chinensis, stirring for 2-5 hours, and uniformly mixing the components to obtain a finished product.

Example 2

Preparing raw materials: taking 15g of biond magnolia flower, 15g of asarum, 25g of muskmelon pedicel, 6g of ligusticum wallichii, 3g of borneol, 15g of centipeda minima, 9g of rhizoma coptidis, 16g of mint, 8g of radix angelicae, 8g of luffa pulp and 5g of artificial musk;

cleaning rhizoma Ligustici Chuanxiong, drying in the shade, soaking in rice wine for 0.5-2 days, taking out, drying in the shade again, parching in casserole for 1-2 hr to remove water in the herbs, parching, grinding, and sieving with 200 mesh sieve; parching flos Magnoliae in marmite at 50 deg.C for 50 min, stopping parching after the villi on flos Magnoliae surface falls off and turns yellow, parching to dry, grinding, and sieving with 200 mesh sieve;

calcining radix Angelicae Dahuricae and Coptidis rhizoma, grinding, and sieving with 200 mesh sieve;

sterilizing herba asari, pedicellus melo, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, herba Centipedae, herba Menthae, fructus Luffae, and artificial Moschus in a steamer for 4 hr, parching the different herbs separately, grinding, and sieving with 200 mesh sieve;

uniformly stirring the prepared medicinal powder, adding the asarum, the muskmelon pedicel, the ligusticum wallichii, the borneol, the centipeda minima, the mint, the vegetable sponge and the artificial musk into a stirrer, uniformly stirring, adding the magnolia flower and the asarum, stirring again, finally adding the angelica dahurica and the coptis chinensis, stirring for 2-5 hours, and uniformly mixing the components to obtain a finished product.

Example 3

Preparing raw materials: taking 12g of biond magnolia flower, 10g of asarum, 18g of muskmelon pedicel, 3g of ligusticum wallichii, 2g of borneol, 8g of centipeda minima, 6g of goldthread root, 13g of mint, 5g of angelica dahurica, 5g of luffa pulp and 1g of artificial musk;

cleaning rhizoma Ligustici Chuanxiong, drying in the shade, soaking in rice wine for 0.5-2 days, taking out, drying in the shade again, parching in casserole for 1-2 hr to remove water in the herbs, parching, grinding, and sieving with 200 mesh sieve; parching flos Magnoliae in marmite at 50 deg.C for 50 min, stopping parching after the villi on flos Magnoliae surface falls off and turns yellow, parching to dry, grinding, and sieving with 200 mesh sieve;

calcining radix Angelicae Dahuricae and Coptidis rhizoma, grinding, and sieving with 200 mesh sieve;

sterilizing herba asari, pedicellus melo, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, herba Centipedae, herba Menthae, fructus Luffae, and artificial Moschus in a steamer for 4 hr, parching the different herbs separately, grinding, and sieving with 200 mesh sieve;

uniformly stirring the prepared medicinal powder, adding the asarum, the muskmelon pedicel, the ligusticum wallichii, the borneol, the centipeda minima, the mint, the vegetable sponge and the artificial musk into a stirrer, uniformly stirring, adding the magnolia flower and the asarum, stirring again, finally adding the angelica dahurica and the coptis chinensis, stirring for 2-5 hours, and uniformly mixing the components to obtain a finished product.

Typical cases are:

serial number

Patient's health

Sex

Age (age)

Time of illness

Causes of disease

Time of administration

Whether the disease is healed or not

Whether or not the disease recurs within 1 year

1

Jia somewhere

For male

65

For 30 years

Viral rhinitis

32 weeks

Recovery method

No recurrence

2

Lie somewhere

For male

51

12 years old

Viral rhinitis

For 16 weeks

Recovery method

No recurrence

3

King of a certain

For male

12

1 year

Allergic rhinitis

8 weeks

Is effective

4

Liu (Chinese character) Gong

Woman

53

For 10 years

Nasosinusitis

24 weeks

Recovery method

No recurrence

5

Lie somewhere

Woman

30

For 3 years

Nasosinusitis

For 12 weeks

Is effective

6

Liu (Chinese character) Gong

Woman

43

5 years old

Atrophic rhinitis

For 16 weeks

Recovery method

No recurrence

7

Horse's horn

For male

57

11 years old

Nasal polyp

For 16 weeks

Recovery method

No recurrence

8

Dong's somebody

Woman

48

7 years old

Nasosinusitis

For 16 weeks

Recovery method

No recurrence

9

Yang Gong

For male

58

11 years old

Viral rhinitis

For 36 weeks

Is effective

10

Chen (a certain)

For male

40

5 years old

Nasal polyp

For 12 weeks

Recovery method

No recurrence

As can be seen from the above table, the rhinitis medicine prepared by the invention is less influenced by the age, sex and illness time in treatment, and has no recurrence after recovery.

And (3) statistical data display:

serial number

Time of illness

Number of patients

The powder of the invention is used for a long time

Dosage and frequency

Rate of recovery

Whether or not the disease is relapsed

1

0-1 year

50

8 weeks

1 time/week

99%

No recurrence

2

1-3 years old

500

10-20 weeks

1 time/week

99%

No recurrence

3

3-8 years old

100

20-30 weeks

1 time/week

98%

No recurrence

4

For more than 8 years

10

30-35 weeks

2 times/week

95%

No recurrence

As can be seen from the above table, the rhinitis drug prepared by the present invention still has a high cure rate when treating a patient with chronic dermatitis, and the shorter the disease duration, the shorter the treatment duration and the higher the cure rate.

According to the data display results, the patient has high recovery rate when using the medicament provided by the invention, and has no relapse after recovery.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (4)

1. A medicine for treating rhinitis is characterized in that: the composite material is characterized by comprising the following raw materials in parts by weight: 6-15 parts of biond magnolia flower, 5-15 parts of asarum, 10-25 parts of muskmelon pedicel, 1-6 parts of ligusticum wallichii, 0.5-3 parts of borneol, 3-15 parts of centipeda minima, 2-9 parts of coptis chinensis, 5-16 parts of mint, 2-8 parts of radix angelicae, 2-8 parts of loofah flesh and 0.5-5 parts of artificial musk.

2. A medicament for the treatment of rhinitis according to claim 1, wherein: 8-12 parts of biond magnolia flower, 6-10 parts of asarum, 12-20 parts of muskmelon pedicel, 2-5 parts of ligusticum wallichii, 1-3 parts of borneol, 5-10 parts of centipeda minima, 4-8 parts of coptis chinensis, 8-12 parts of mint, 3-6 parts of radix angelicae, 3-6 parts of loofah sponge and 1-3 parts of artificial musk.

3. A medicament for the treatment of rhinitis according to claim 1, wherein: 9 parts of biond magnolia flower, 9 parts of asarum, 15 parts of muskmelon pedicel, 3 parts of ligusticum wallichii, 3 parts of borneol, 9 parts of centipeda minima, 5 parts of goldthread root, 9 parts of mint, 4 parts of radix angelicae, 5 parts of luffa pulp and 2 parts of artificial musk.

4. A process for the preparation of a medicament as claimed in any one of claims 1 to 3 for the treatment of rhinitis, characterized in that: the preparation method comprises the following preparation steps:

step 1: preparing medicinal materials, namely cleaning flos magnoliae, asarum, muskmelon pedicel, ligusticum wallichii, borneol, centipeda minima, goldthread root, mint, radix angelicae, loofah sponge and artificial musk, removing dirt and drying in the shade;

step 2: soaking rhizoma Ligustici Chuanxiong in rice wine for pretreatment;

and step 3: parching flos Magnoliae in casserole at 30-50 deg.C for 30-60 min until the surface of flos Magnoliae turns yellow, grinding, and sieving with 200 mesh sieve;

and 4, step 4: calcining radix Angelicae Dahuricae and Coptidis rhizoma, grinding, and sieving with 200 mesh sieve;

and 5: sterilizing herba asari, pedicellus melo, rhizoma Ligustici Chuanxiong, Borneolum Syntheticum, herba Centipedae, herba Menthae, fructus Luffae, and artificial Moschus in a steamer for 3-5 hr, parching the different herbs separately, grinding, and sieving with 200 mesh sieve;

step 6: and (3) proportioning the standby materials obtained in the steps 1-5, uniformly stirring and preparing into powder.