CN100471509C - Medicine for treating tympanitis and otitis externa, and preparing method - Google Patents

Medicine for treating tympanitis and otitis externa, and preparing method Download PDF

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CN100471509C
CN100471509C CNB2005100072195A CN200510007219A CN100471509C CN 100471509 C CN100471509 C CN 100471509C CN B2005100072195 A CNB2005100072195 A CN B2005100072195A CN 200510007219 A CN200510007219 A CN 200510007219A CN 100471509 C CN100471509 C CN 100471509C
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medicine
otitis
otitis media
treatment
margarita
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CN1813955A (en
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刘金荣
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Abstract

The present invention relates to a Chinese medicine for curing otitis media and otitis externa and its preparation method. It is made up by using the Chinese medicinal materials of musk and pearl as main component. Its effective rate and cure rate are high.

Description

A kind of medicine that is used for the treatment of otitis media, otitis externa and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of otitis media, otitis externa, specifically the present invention relates to medicament in a kind of external for the treatment of otitis media, otitis externa.
Background technology
Otitis media is a kind of commonly encountered diseases, and doctor trained in Western medicine claims " secreted " or " Catarrhal " otitis media etc., is one of difficult disease of department of eye, most eustachian tube obstruction cause that the ear pressure increases, and are congested in the tympanum, and the blood vessel wall permeability is strengthened, blood oozes out, and hydrops increases swelling in the tympanum.Then symptoms such as ear chamber swelling pain have been caused.Above-mentioned symptom can not get treating timely and effectively and qi and blood stagnation, skin infection will occur, flows out weak yellow liquid, until suppuration, even causes deafness, tinnitus etc.
Otitis media belongs at the beginning of the row of categories such as " deafness, bulge of the ear " in the traditional Chinese medical science.From the beginning of be " lacking sun heat ", " dialectical criterion " record " ear is suffered from different, due to all the few sun of genus foot, hands few positive two are stopped up " on pathogenic heat.The affection due to external wind and heat invasion and attack, two stop up on pathogenic heat, and knot gathers in ear.
At present, the western medicine otitis media poor effect of clinical employing does not reach the radical cure effect, causes outbreak repeatedly, and certain side effect is arranged, otalgia itching in the ear after the medication.For, the otitis media of aseptic symptom, western medicine result is bad.At present, then effect is slow for the treatment by Chinese herbs otitis media of employing, and the course of treatment is long, can not effect a radical cure, and effective percentage and cure rate are low, and cost an arm and a leg, complex manufacturing technology.
Application number is that 88105155.1 application for a patent for invention discloses a kind of medicine and the manufacture method that can treat otitis media, and its pharmaceutical formulation is: Herba Taraxaci 40-60 grams, Herba Scutellariae Barbatae 40g-60g, catechu 20g-40g, Margarita 20g-40g, Moschus 5g-15g, Herba Solani Lyrati 50g-70g, succinum 50g-70g, Cornu rhinocerotis 30g-50g, Radix Glycyrrhizae 120g-140g, respect 50g-70g in vain, Herba Albiziae 20g-40g, Radix Ophiopogonis village 50g-70g, old Colla Corii Asini 50g-70g, Borax 30g-50g, Borneolum Syntheticum 50g-70g, Cordyceps 30g-50g, Cortex Magnoliae Officinalis 50g-70g, Radix Angelicae Sinensis 70g-90g, beeswax 90g-110g.The medicine of this patent application has no side effects, advantage widely applicable, safe and convenient to use, but this medicine does not provide therapeutic effect, does not provide effective percentage and cure rate, and this medicine material is many, and is with high costs, complex manufacturing technology.
Summary of the invention
The purpose of this invention is to provide a kind of with low cost, make simple, easy to use, the scope of application extensively, short treating period, instant effect, can thoroughly effect a radical cure do not recur, no side effects, the treatment otitis media that effective percentage and cure rate are high, the Chinese medicine of otitis externa.
The present invention makes through clinical practice for many years and research on the basis of secret prescription handed down in the family from generation to generation.The cause of disease, pathogenesis according to otitis media, the present invention adopts Moschus, and " orifice opening; separate the effect of strange poison; be equipped with the cold medicine of Margarita, Borneolum Syntheticum, Rhizoma Coptidis; reach heat clearing away, detoxifcation, aim of alleviating pain; be equipped with Olibanum, Myrrha blood circulation promoting and blood stasis dispelling and Margarita compatibility has more also just had the special effect of putrefaction-removing granulation-promoting, and the Calomelas removing dampness is antipruritic.The Chinese medicine of preparation according to the present invention has the function of reducing swelling and alleviating pain, putrefaction-removing granulation-promoting.Chinese medicine of the present invention also can be treated otitis externa.Chinese medicine of the present invention can also be treated all other inflammation of external ear and middle ear and eczema, skin infection etc.
Technical scheme of the present invention is: a kind of medicine for the treatment of otitis media, otitis externa comprises the following component of note by weight: Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8.
The preferred version of technical solution of the present invention is: Moschus 0.3-1.5, Margarita 0.3-1.5, Olibanum 1.5-3, Myrrha 2-3, Borneolum Syntheticum 1-2, Rhizoma Coptidis 4-6.
Another preferred version of technical solution of the present invention: Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8, Calomelas 0.05-0.1.
The most preferably scheme of technical solution of the present invention: Moschus 0.3-1.5, Margarita 0.3-1.5, Olibanum 1.5-3, Myrrha 2-3, Borneolum Syntheticum 1-2, Rhizoma Coptidis 4-6, Calomelas 0.07-0.1.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention can be made: powder, drop, unguentum.
The said pretreatment of the present invention is meant: get the various medical materials (except that glycerol, vaseline) in the technical solution of the present invention, screen, the medical material of screening under 60--80 ℃ temperature, dry 2-6 hours, is reached and removes moisture and make the unlikely degree that loses effect of medical material again.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention, the method of making powder is: (1), get and carry out the pretreated medical material that is respectively Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8 by weight, and standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention, another method of making powder is: (1), get and carry out the pretreated medical material that is respectively Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8, Calomelas 0.05-0.1 by weight, and standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention, the method of making drop is: (1), get carry out pretreated be respectively by weight Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8, medical material, standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.(4), add powder weight 6---10 glycerol doubly, mixing, the drop of formation liquid.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention, another method of making drop is: (1), get and carry out the pretreated medical material that is respectively Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8, Calomelas 0.05-0.1 by weight, and standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.(4), add powder weight 6---10 glycerol doubly, mixing, the drop of formation liquid.
A kind of medicine for the treatment of otitis media, otitis externa of the present invention, the method for making unguentum is: obtain powder according to the aforementioned method of producing powder, add the vaseline of 1-2 times of powder weight, mixing is paste, forms unguentum.
Using method:
The using method of powder:
One day twice, once about 0.05g, 3 days 1 courses of treatment.Powder is to having ulcer surface and suppurative otitis media effect better.Method evenly is sprayed on the in ear affected part and gets final product for getting powder.
The using method of drop:
Twice, one time on the one 0.25----0.5ml (about 5---10 drips), 3 days 1 courses of treatment.Drop is red and swollen but do not have ulcer surface and otitis media to take a turn for the better through treating after to form a scab effect better to the otitis media initial stage.Method is for to splash into the in ear affected part with suction pipe.
The using method of unguentum:
One day twice, once about 0.1g, 3 days 1 courses of treatment.Method is evenly coated in the in ear affected part and gets final product for getting unguentum.
According to 100 routine case observation statistics, sex, man, 65 people; The woman, 35 people; 30 years old mean age; Course of disease elder 20 years, 1 week of weak point person.Wherein, red and swollen but person 30 people that do not have the ulcer surface of otitis media initial stage; Fester in the in ear affected part, no pus person 20 people; Suppuration symptom 50 people; Acute otitis media 20 people, chronic otitis media 80 people; Cure 70 people a course of treatment, cure 20 people two courses of treatment; Cure 7 people three courses of treatment.Clinical cure 97 people, all the other 3 people's produce effects, total effective rate 100%, obvious effective rate 100%, cure rate 97%.
Can see that from technical scheme of the present invention because crude drug has only six, seven flavors, and manufacturing process only relates to drying, physical pulverization and mixing, so the present invention has the simple advantage of making.
Can see from using method, Drug therapy otitis media of the present invention, easy to use.
Use medicine of the present invention, because short treating period, each dosage is few, and the low price of medicine itself is therefore, with low cost.
Use Drug therapy otitis media short treating period of the present invention, instant effect.
Use Drug therapy otitis media of the present invention, effective percentage and cure rate height have and can thoroughly effect a radical cure the advantage that does not recur.
Can see that according to above-mentioned statistical data the Chinese medicine scope of application of the present invention is extensive, for the red and swollen but person's (otitis media of aseptic symptom) that do not have the ulcer surface of otitis media initial stage, suppurative otitis media, and various acute and chronic otitis media are all effective.
Specify the present invention with embodiment below, but do not limit the present invention.
Embodiment one:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis respectively, carry out pretreatment: medical material is screened, put into baking oven, 60 ℃ of dryings 4 hours.
Get pretreated Moschus 0.1g, Margarita 0.1g, Olibanum 1g, Myrrha 1g, Borneolum Syntheticum 0.5g, Rhizoma Coptidis 4g, grind, pulverize is crossed 150 mesh sieves, mixing, obtains powder.
Embodiment two:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis respectively, carry out pretreatment: medical material is screened, put into baking oven, 60 ℃ of dryings 2 hours.
Get pretreated Moschus 2g, Margarita 2g, Olibanum 4g, Myrrha 4g, Borneolum Syntheticum 3g, Rhizoma Coptidis 8g, grind, pulverize is crossed 120 mesh sieves, mixing, obtains powder.
Embodiment three:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis respectively, carry out pretreatment: medical material is screened, put into baking oven, 80 ℃ of dryings 2 hours.
Get pretreated Moschus 0.3g, Margarita 0.3g, Olibanum 1.5g, Myrrha 2g, Borneolum Syntheticum 1g, Rhizoma Coptidis 4g, grind, pulverize is crossed 90 mesh sieves, mixing, obtains powder.
Embodiment four:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis respectively, carry out pretreatment: medical material is screened, put into baking oven, 60 ℃ of dryings 6 hours.
Get pretreated Moschus 1.5g, Margarita 1.5g, Olibanum 3g, Myrrha 3g, Borneolum Syntheticum 2g, Rhizoma Coptidis 6g, grind, pulverize is crossed 100 mesh sieves, and mixing obtains powder.
Embodiment five:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment: medical material is screened, put into baking oven, 60 ℃ of dryings 2 hours.
Get pretreated Moschus 0.1g, Margarita 0.1g, Olibanum 1g, Myrrha 1g, Borneolum Syntheticum 0.5g, Rhizoma Coptidis 4g, Calomelas 0.05g grinds, and pulverize is crossed 100 mesh sieves, and mixing obtains powder.
Embodiment six:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment:
Medical material is screened, put into baking oven, 80 ℃ of dryings 2 hours.
Get pretreated Moschus 2g, Margarita 2g, Olibanum 4g, Myrrha 4g, Borneolum Syntheticum 3g, Rhizoma Coptidis 8g, Calomelas 0.1g grinds, and pulverize is crossed 150 mesh sieves, mixing, obtains powder.
Embodiment seven:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment: medical material is screened, put into baking oven, 80 ℃ of dryings 4 hours.
Get pretreated Moschus 0.3g, Margarita 0.3g, Olibanum 1.5g, Myrrha 2g, Borneolum Syntheticum 1g, Rhizoma Coptidis 4g, Calomelas 0.07g grinds, and pulverize is crossed 90 mesh sieves, mixing, obtains powder.
Embodiment eight:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment: medical material is screened, put into baking oven, 80 ℃ of dryings 3 hours.
Get pretreated Moschus 1.5g, Margarita 1.5g, Olibanum 3g, Myrrha 3g, Borneolum Syntheticum 2g, Rhizoma Coptidis 6g, Calomelas 0.1g grinds, and pulverize is crossed 120 mesh sieves, and mixing obtains powder.
Embodiment nine:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment: medical material is screened, put into baking oven, 60 ℃ of dryings 6 hours.
Get pretreated Moschus 0.1g, Margarita 0.1g, Olibanum 1g, Myrrha 1g, Borneolum Syntheticum 0.5g, Rhizoma Coptidis 4g, Calomelas 0.05g grinds, and pulverize is crossed 100 mesh sieves, and mixing obtains powder;
Powder is added in the 40.5g glycerol, and mixing obtains drop.
Embodiment ten:
Get Moschus, Margarita, Olibanum, Myrrha, Borneolum Syntheticum, Rhizoma Coptidis, Calomelas respectively, carry out pretreatment: medical material is screened, put into baking oven, 80 ℃ of dryings 6 hours.
Get pretreated Moschus 2g, Margarita 2g, Olibanum 4g, Myrrha 4g, Borneolum Syntheticum 3g, Rhizoma Coptidis 8g, Calomelas 0.1g grinds, and pulverize is crossed 130 mesh sieves, and mixing obtains powder; Powder is added in the 23.1g vaseline, and mixing obtains unguentum.

Claims (9)

1, a kind of medicine for the treatment of otitis media, otitis externa is characterized in that comprising the following component of note by weight: Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8.
2, according to the medicine of the described treatment otitis media of claim 1, otitis externa, it is characterized in that comprising following component by weight: Moschus 0.3-1.5, Margarita 0.3-1.5, Olibanum 1.5-3, Myrrha 2-3, Borneolum Syntheticum 1-2, Rhizoma Coptidis 4-6.
3, according to the medicine of the described treatment otitis media of claim 1, otitis externa, it is characterized in that also adding following component by weight: Calomelas 0.05-0.1.
4, the medicine of treatment otitis media according to claim 2, otitis externa is characterized in that also adding following component by weight: Calomelas 0.07-0.1.
5, according to claim 1,2,3,4 one of them a kind of medicines for the treatment of otitis media, otitis externa, it is characterized in that said medicine is powder or drop or unguentum.
6, a kind of method for preparing the medicine of treatment otitis media, otitis externa, it is characterized in that: (1), get the medical material that is respectively Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8 by weight after handling, standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.
7, a kind of method for preparing the medicine of treatment otitis media, otitis externa, it is characterized in that: (1), get the medical material that is respectively Moschus 0.1-2, Margarita 0.1-2, Olibanum 1-4, Myrrha 1-4, Borneolum Syntheticum 0.5-3, Rhizoma Coptidis 4-8, Calomelas 0.05-0.1 by weight after handling, standby; (2), the medical material of getting ready is ground pulverize, 90-150 mesh sieves excessively; (3), mixing, form powder.
8, prepare the method for the medicine of treatment otitis media, otitis externa according to claim 6,7 one of them a kind of, it is characterized in that: with formed powder, add in the glycerol of 6-10 times of powder weight, mixing forms the drop of liquid.
9, prepare the method for the medicine of treatment otitis media, otitis externa according to claim 6,7 one of them a kind of, it is characterized in that: with formed powder, add in the vaseline of 1-2 times of powder weight, mixing is paste, forms unguentum.
CNB2005100072195A 2005-02-05 2005-02-05 Medicine for treating tympanitis and otitis externa, and preparing method Expired - Fee Related CN100471509C (en)

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CN103893562B (en) * 2014-04-19 2016-03-30 郭冬梅 A kind of medicine and preparation method for the treatment of otitis externa
CN104306509A (en) * 2014-11-07 2015-01-28 刘诗音 Traditional Chinese medicine preparation for treating hearing loss and tinnitus and preparation method of traditional Chinese medicine preparation
CN104800279A (en) * 2015-04-23 2015-07-29 王红垒 Traditional Chinese medicine for treating pediatric acute otitis media
CN104784385A (en) * 2015-05-05 2015-07-22 李作娟 Medicine for treating aural vertigo and preparation method thereof
CN105169202A (en) * 2015-09-24 2015-12-23 烟台瑞智生物医药科技有限公司 Traditional Chinese medicine composition for treating qi and blood stasis blocking syndrome type deafness
CN105641661A (en) * 2016-02-26 2016-06-08 郭冬梅 Traditional Chinese medicine preparation for treating otitis externa and preparation method
CN105748934A (en) * 2016-04-28 2016-07-13 杨小平 Traditional Chinese medicine preparation for treating otitis externa and preparation method
CN108079050A (en) * 2018-02-06 2018-05-29 张朋伟 Herbal skin bacteria inhibiting composition and preparation method and application

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