CN113115885A - Mulberry leaf extract beverage - Google Patents
Mulberry leaf extract beverage Download PDFInfo
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- CN113115885A CN113115885A CN202110462148.7A CN202110462148A CN113115885A CN 113115885 A CN113115885 A CN 113115885A CN 202110462148 A CN202110462148 A CN 202110462148A CN 113115885 A CN113115885 A CN 113115885A
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- medlar
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention provides a mulberry leaf extract beverage which comprises the following raw materials in parts by weight: the mulberry leaf extract is 90-100 parts, has various physiological activities of obviously reducing blood sugar, blood pressure, bacteria and viruses and the like, and has the characteristics of mild and lasting effect, small toxic and side effects and the like. Moreover, the solid beverage adopts the extract, so that the content of the effective components is high, and the effect is good after drinking; meanwhile, the medicine is suitable for the condition that patients with hyperglycemia suffer from hypertension, hyperlipidemia and hypercholesterolemia at the same time.
Description
Technical Field
The invention relates to the technical field of drinks, in particular to a mulberry leaf extraction solid beverage.
Background
Diabetes is a metabolic disease characterized by hyperglycemia due to defective insulin secretion or impaired insulin action. Persistent hyperglycemia and long-term metabolic disorders, among others, can lead to damage to and dysfunction and failure of systemic tissues and organs, particularly the eye, kidney, cardiovascular and nervous systems. At present, the population suffering from the diabetes is continuously increased in China and even worldwide, according to incomplete statistics, more than 95 percent of 1.2 hundred million diabetes patients are type 2 in China, and more than 5 million people are in the period of blood sugar damage.
Diabetes mellitus is gradually caused to erode the human body, is caused by the factors such as liver, epinephrine disorder, hyperlipidemia, mental stress and internal excess stress, produces endocrine dyscrasia in stress for a long time, causes nervous system disorder, dysfunction of storage and release of hepatic glycogen of liver, and finally causes the gradual rise of blood sugar in blood. The pancreatic islets secrete two substances, namely insulin and glucagon, which are balanced, but due to pancreatic islet dysfunction, secretion is uneven, glucagon secretion is increased, and blood sugar is pulled to rise.
At present, in clinical practice, aiming at the diseases, the traditional antagonism therapy is adopted, most of drug therapies are typical antagonism therapies (such as oral western medicines or insulin), but the antagonism therapy effect is poor, the drug therapy can only be maintained by adding dosage, and the drug resistance is gradually generated, so that complications are increased, a large amount of insulin and drugs are used, the side effect is great, and the blood sugar is higher and higher, so that the life span and the life quality of people are seriously affected. There are statistics in the united states that 80% of diabetics die of coronary heart disease. In addition, many kinds of complications such as eye, nerve, kidney, skin, sexual function, etc. are also very common.
For curing diabetes radically, scientific drinking is very important. If the diabetics or people with high blood sugar can drink alkalescent water or drink convenient to carry, the health care tea can greatly help to balance nutrition, balance acid and alkali, improve acidic constitution and eliminate diabetes.
Meanwhile, due to the improvement of the quality of life, more and more patients with hyperlipidemia, hypertension and hypercholesterolemia tend to be younger. Hyperlipidemia can cause vascular embolism; hypertension can cause cerebral hemorrhage and cerebral vascular rupture; high cholesterol easily causes the blockage of coronary artery of heart, and leads to cardiovascular diseases such as myocardial infarction, angina, sudden death and the like. Therefore, effective measures must be taken to prevent the occurrence of hyperlipidemia, hypertension, and hypercholesterolemia. Currently, for hyperlipidemia, hypertension and hypercholesterolemia, chemical treatment is generally adopted. Although effective in treatment, the middle-aged and elderly people have liver and kidney function reduction, and are affected by various diseases and medicines, so that drug-induced diseases and iatrogenic death are caused. Therefore, the development of the health food for patients with hyperlipidemia, hypertension and hypercholesterolemia which is homologous in medicine and food is a necessary trend of social development.
Disclosure of Invention
The invention aims to provide a mulberry leaf extraction solid beverage to relieve the technical problems of hyperglycemia at the present stage and treat hypertension, high fat and high cholesterol caused by lack of exercise and no attention on diet.
In order to achieve the technical effects, the invention adopts the following technical scheme:
a mulberry leaf extraction solid beverage is developed and comprises the following raw materials in parts by weight: 90-100 parts of mulberry leaf extract.
Preferably, the feed comprises the following raw materials in parts by weight: 90-100 parts of mulberry leaf extract, 1-3 parts of medlar extract, 1-3 parts of bitter gourd extract, 1-2 parts of polygonatum extract, 1-2 parts of honeysuckle extract and 0.2-0.5 part of ginseng extract.
Preferably, the feed comprises the following raw materials in parts by weight: 92 parts of mulberry leaf, 2.7 parts of medlar extract, 2 parts of balsam pear extract, 1.5 parts of polygonatum extract, 1.5 parts of honeysuckle extract and 0.3 part of ginseng extract.
Preferably, the preparation method of the mulberry leaf extract comprises the following steps:
t1: cleaning folium Mori, drying under natural condition or vacuum, crushing, and sieving;
t2: subcritical CO2And (3) extraction: the extraction pressure is 5-15 MPa, the extraction temperature is 15-30 ℃, and CO is added2The flow rate is 170-180L/h, and the extraction time is 3-4 h, so that a primary product of the mulberry leaf extract is obtained;
t3: then carrying out secondary separation in a rectifying tower, wherein the separation pressure is 10-30 MPa, the separation temperature is 40-60 ℃, and the rectifying liquid passes through cation exchange resin and then stands for adsorption for 1-3 hours; eluting with purified water, and eluting with ammonia water to obtain ammonia water eluate;
t4: concentrating and drying the ammonia water eluate to obtain folium Mori extract.
Preferably, the preparation method of the medlar extract comprises the following steps:
(1) drying, crushing and sieving the medlar, and performing water leaching according to the volume ratio of material liquid to water of 1: 50-100 to obtain leaching liquor;
(2) grinding the leaching liquor obtained in the step (1) by using a colloid mill, and homogenizing under the pressure of 120-200 MPa to obtain supernatant and filter residue;
(3) adsorbing the filtrate by using non-polar macroporous adsorption resin, eluting the filtrate by using deionized water until the filtrate is sugar-free, and eluting the medlar extract adsorbed on the macroporous resin by using 2-50 times of bed layer volume and 40-100% of ethanol solution by mass concentration to obtain eluent containing the medlar extract;
(4) and concentrating the eluent containing the medlar extract under vacuum reduced pressure, and drying the eluent under vacuum to obtain the medlar extract.
Preferably, the preparation method of the balsam pear extract comprises the following steps:
s1, selecting fresh whole bitter gourd, slicing, drying, crushing to obtain bitter gourd powder, uniformly mixing the bitter gourd powder and water according to a mass ratio of 1:5, extracting by adopting low-temperature water extraction to obtain an extracting solution, filtering the extracting solution under reduced pressure to obtain a filtrate, and performing filter pressing to obtain a bitter gourd extract;
s2: separating the obtained extract of fructus Momordicae Charantiae with nanometer membrane, and adsorbing with macroporous resin to remove impurities;
s3: adding yeast into the fructus Momordicae Charantiae extract after removing impurities, fermenting at low temperature, and drying to obtain fructus Momordicae Charantiae extract.
Compared with the prior art, the invention has the beneficial technical effects that:
the mulberry leaf extract disclosed by the invention is cold in nature, sweet and bitter in taste, has the effects of dispelling wind and heat, clearing lung and moistening dryness, and clearing liver and improving vision, and is one of the traditional Chinese medicines commonly used in clinic. Modern researches show that alkaloid components contained in mulberry leaves have obvious effect of regulating blood sugar; the flavonoids and polysaccharides in folium Mori have effects in regulating blood sugar and preventing and treating complications. In addition, the mulberry leaves also contain various functional components, such as phytosterol, trace elements, vitamins, amino acids and the like. The mulberry leaf extract has various physiological activities of reducing blood sugar, reducing blood pressure, resisting bacteria, resisting viruses and the like, and has the characteristics of mild and lasting effect, small toxic and side effect and the like. Moreover, the solid beverage adopts the extract, so that the content of the effective components is high, and the effect is good after drinking; meanwhile, the health-care food is suitable for the condition that patients with hyperglycemia suffer from hypertension, hyperlipidemia and hypercholesterolemia at the same time, can obviously relieve the blood sugar of the patients with diabetes in 3 to 6 months, and can eliminate the blood sugar of the patients suffering from hyperlipidemia independently after being taken for 3 months.
Furthermore, the bitter gourd extract is rich in various bioactive components, has the effects of clearing away heat and toxic materials, resisting tumors, assisting in reducing blood sugar concentration, resisting mutation, enhancing immunity and the like, and shows wide application prospects in the aspects of food and medicine.
Furthermore, the lycium ruthenicum extract has the effects of resisting oxidation, activating macrophages, resisting aging and the like, the lycium ruthenicum contains rich anthocyanin, and the anthocyanin has the functions of resisting oxidation, free radicals, resisting aging and the like, can inhibit inflammation and allergy, enhance the elasticity of blood vessels of a human body, and improve the flexibility of joints to relieve the abnormal rise of blood sugar after meal to a certain extent. Has effects in resisting fatty liver, resisting atherosclerosis, nourishing liver, protecting liver, and reducing blood sugar.
Furthermore, the ginseng extract is sweet and slightly bitter in taste, mild in nature and mild in temperature, and has the effects of greatly tonifying primordial qi, tonifying spleen and lung, promoting the production of body fluid to quench thirst, and soothing nerves and improving intelligence. Palpitation, amnesia, vertigo, headache, impotence, frequent micturition, diabetes, metrorrhagia, chronic infantile convulsion, and deficiency of both qi, blood and body fluid.
Detailed Description
The following examples are given to illustrate specific embodiments of the present invention, but are not intended to limit the scope of the present invention in any way. (ii) a The raw materials are all conventional commercial industrial raw materials if not specifically indicated; the processing and manufacturing methods are conventional methods unless otherwise specified.
Example 1: a mulberry leaf extraction solid beverage comprises the following raw materials in parts by weight: 92 parts of mulberry leaf, 2.7 parts of medlar extract, 2 parts of balsam pear extract, 1.5 parts of polygonatum extract, 1.5 parts of honeysuckle extract and 0.3 part of ginseng extract.
Preferably, the preparation method of the mulberry leaf extract comprises the following steps:
t1: cleaning folium Mori, drying under natural condition or vacuum, crushing, and sieving;
t2: subcritical CO2And (3) extraction: the extraction pressure is 10MPa, the extraction temperature is 30 ℃, and CO is added2The flow rate is 175L/h, and the extraction time is 3.5h, so as to obtain a mulberry leaf extract primary product;
t3: then carrying out secondary separation in a rectifying tower at the separation pressure of 20MPa and the separation temperature of 55 ℃, and then standing and adsorbing the rectification liquid for 2 hours through cation exchange resin; eluting with purified water, and eluting with ammonia water to obtain ammonia water eluate;
t4: concentrating and drying the ammonia water eluate to obtain folium Mori extract.
Preferably, the preparation method of the medlar extract comprises the following steps:
(1) drying fructus Lycii, pulverizing, sieving, and performing water extraction at a material liquid volume ratio of 1: 80 to obtain extract;
(2) grinding the leaching liquor obtained in the step (1) by a colloid mill, and homogenizing under the pressure of 150MPa to obtain supernatant and filter residue;
(3) adsorbing the filtrate by using non-polar macroporous adsorption resin, eluting by using deionized water until the filtrate is sugar-free, and eluting the medlar extract adsorbed on the macroporous resin by using ethanol solution with 48 times of bed layer volume and 75% of mass concentration to obtain eluent containing the medlar extract;
(4) and concentrating the eluent containing the medlar extract under vacuum reduced pressure, and drying the eluent under vacuum to obtain the medlar extract.
Preferably, the preparation method of the balsam pear extract comprises the following steps:
s1, selecting fresh whole bitter gourd, slicing, drying, crushing to obtain bitter gourd powder, uniformly mixing the bitter gourd powder and water according to a mass ratio of 1:5, extracting by adopting low-temperature water extraction to obtain an extracting solution, filtering the extracting solution under reduced pressure to obtain a filtrate, and performing filter pressing to obtain a bitter gourd extract;
s2: separating the obtained extract of fructus Momordicae Charantiae with nanometer membrane, and adsorbing with macroporous resin to remove impurities;
s3: adding yeast into the fructus Momordicae Charantiae extract after removing impurities, fermenting at low temperature, and drying to obtain fructus Momordicae Charantiae extract.
Example 2: the difference from example 1 is that:
a mulberry leaf extraction solid beverage comprises the following raw materials in parts by weight: 93 parts of mulberry leaf, 1.7 parts of medlar extract, 2 parts of balsam pear extract, 1.5 parts of polygonatum extract, 1.5 parts of honeysuckle extract and 0.3 part of ginseng extract.
Preferably, the preparation method of the mulberry leaf extract comprises the following steps:
t1: cleaning folium Mori, drying under natural condition or vacuum, crushing, and sieving;
t2: subcritical CO2And (3) extraction: the extraction pressure is 12MPa, the extraction temperature is 25 ℃, and CO is added2The flow rate is 175L/h, and the extraction time is 3.5h, so as to obtain a mulberry leaf extract primary product;
t3: then carrying out secondary separation in a rectifying tower at the separation pressure of 30MPa and the separation temperature of 50 ℃, and then standing and adsorbing the rectification liquid for 3 hours through cation exchange resin; eluting with purified water, and eluting with ammonia water to obtain ammonia water eluate;
t4: concentrating and drying the ammonia water eluate to obtain folium Mori extract.
Example 3: the difference from example 1 is that:
a mulberry leaf extraction solid beverage comprises the following raw materials in parts by weight: 94 parts of mulberry leaf, 1.7 parts of medlar extract, 2 parts of balsam pear extract, 1 part of polygonatum extract, 1 part of honeysuckle extract and 0.3 part of ginseng extract.
Preferably, the preparation method of the mulberry leaf extract comprises the following steps:
t1: cleaning folium Mori, drying under natural condition or vacuum, crushing, and sieving;
t2: subcritical CO2And (3) extraction: the extraction pressure is 12MPa, the extraction temperature is 25 ℃, and CO is added2The flow rate is 175L/h, and the extraction time is 3.5h, so as to obtain a mulberry leaf extract primary product;
t3: then carrying out secondary separation in a rectifying tower at the separation pressure of 30MPa and the separation temperature of 50 ℃, and then standing and adsorbing the rectification liquid for 3 hours through cation exchange resin; eluting with purified water, and eluting with ammonia water to obtain ammonia water eluate;
t4: concentrating and drying the ammonia water eluate to obtain folium Mori extract.
Effect example 1
The mulberry leaf extract beverage obtained by the invention is directly put into water for taking. Aiming at people who need to inject insulin every day and suffer from hypertension, hyperglycemia and hyperlipidemia, the following symptoms (with different disease severity and difference) can appear within 1-6 months when taking the mulberry leaf extract beverage:
stage 1: the vision of the eyes becomes clear, which also indicates that the blood supply of the brain is improved, the thirst is slightly relieved, and the eyeground can reflect the blood supply condition of cerebral arteries (1-2 months);
and (2) stage: the amount of western medicines orally taken by a patient without insulin is gradually reduced, the patient occasionally does not eat on time, feels hungry, but does not have hypoglycemia symptoms (cold sweat, palpitation, weakness and the like), and the condition that the blood sugar self-regulation capability is improved and the complexion is good (the time of 2-3 months) is shown;
and (3) stage: the heart function is improved, the coronary heart disease symptoms are gradually improved, the exercise tolerance is obviously improved, and the sexual function is improved (within 3-4 months);
and (4) stage: improving kidney function, improving proteinuria, obviously improving hyperlipidemia and fatty liver, and avoiding special administration of lipid-lowering drugs (4-5 months);
and (5) stage: the nervous system felt better (after 5 months).
Although the present invention has been described in detail with reference to the embodiments, it will be understood by those skilled in the art that various changes in the specific parameters of the embodiments may be made without departing from the spirit of the present invention, and a plurality of specific embodiments are formed, which are common variations of the present invention, and will not be described in detail herein.
Claims (6)
1. The mulberry leaf extraction solid beverage is characterized by comprising the following raw materials in parts by weight: 90-100 parts of mulberry leaf extract.
2. The mulberry leaf extract beverage according to claim 1, comprising the following raw materials in parts by weight: 90-100 parts of mulberry leaf extract, 1-3 parts of medlar extract, 1-3 parts of bitter gourd extract, 1-2 parts of polygonatum extract, 1-2 parts of honeysuckle extract and 0.2-0.5 part of ginseng extract.
3. The mulberry leaf extract beverage according to claim 1, comprising the following raw materials in parts by weight: 92 parts of mulberry leaf, 2.7 parts of medlar extract, 2 parts of balsam pear extract, 1.5 parts of polygonatum extract, 1.5 parts of honeysuckle extract and 0.3 part of ginseng extract.
4. The mulberry leaf extract beverage according to claim 1, wherein the preparation method of the mulberry leaf extract comprises the steps of:
t1: cleaning folium Mori, drying under natural condition or vacuum, crushing, and sieving;
t2: subcritical CO2And (3) extraction: the extraction pressure is 5-15 MPa, the extraction temperature is 15-30 ℃, and CO is added2The flow rate is 170-180L/h, and the extraction time is 3-4 h, so that a primary product of the mulberry leaf extract is obtained;
t3: then carrying out secondary separation in a rectifying tower, wherein the separation pressure is 10-30 MPa, the separation temperature is 40-60 ℃, and the rectifying liquid passes through cation exchange resin and then stands for adsorption for 1-3 hours; eluting with purified water, and eluting with ammonia water to obtain ammonia water eluate;
t4: concentrating and drying the ammonia water eluate to obtain folium Mori extract.
5. The mulberry leaf extract beverage according to claim 1, wherein the preparation method of the wolfberry extract comprises the following steps:
drying, crushing and sieving the medlar, and performing water leaching according to the volume ratio of material liquid to water of 1: 50-100 to obtain leaching liquor;
grinding the leaching liquor obtained in the step (1) by using a colloid mill, and homogenizing under the pressure of 120-200 MPa to obtain supernatant and filter residue;
adsorbing the filtrate by using non-polar macroporous adsorption resin, eluting the filtrate by using deionized water until the filtrate is sugar-free, and eluting the medlar extract adsorbed on the macroporous resin by using 2-50 times of bed layer volume and 40-100% of ethanol solution by mass concentration to obtain eluent containing the medlar extract;
and concentrating the eluent containing the medlar extract under vacuum reduced pressure, and drying the eluent under vacuum to obtain the medlar extract.
6. The mulberry leaf extract beverage according to claim 1, wherein the preparation method of the momordica charantia extract comprises the steps of:
s1, selecting fresh whole bitter gourd, slicing, drying, crushing to obtain bitter gourd powder, uniformly mixing the bitter gourd powder and water according to a mass ratio of 1:5, extracting by adopting low-temperature water extraction to obtain an extracting solution, filtering the extracting solution under reduced pressure to obtain a filtrate, and performing filter pressing to obtain a bitter gourd extract;
s2: separating the obtained extract of fructus Momordicae Charantiae with nanometer membrane, and adsorbing with macroporous resin to remove impurities;
s3: adding yeast into the fructus Momordicae Charantiae extract after removing impurities, fermenting at low temperature, and drying to obtain fructus Momordicae Charantiae extract.
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