CN113069467A - 用作药物或膳食活性成分的多孔二氧化硅材料 - Google Patents

用作药物或膳食活性成分的多孔二氧化硅材料 Download PDF

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Publication number
CN113069467A
CN113069467A CN202110214365.4A CN202110214365A CN113069467A CN 113069467 A CN113069467 A CN 113069467A CN 202110214365 A CN202110214365 A CN 202110214365A CN 113069467 A CN113069467 A CN 113069467A
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China
Prior art keywords
pores
silica
range
porous silica
pore size
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English (en)
Chinese (zh)
Inventor
罗伯特·斯卡兹
托尔·本特松
纳塔利娅·库普弗施密特
阿方索·E·加西亚-班尼特
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Nanologica AB
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Nanologica AB
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015Inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00Silicon; Compounds thereof
    • C01B33/113Silicon oxides; Hydrates thereof
    • C01B33/12Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00Physical properties of inorganic compounds
    • C01P2006/12Surface area
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00Physical properties of inorganic compounds
    • C01P2006/14Pore volume
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00Physical properties of inorganic compounds
    • C01P2006/16Pore diameter
    • C01P2006/17Pore diameter distribution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Silicon Compounds (AREA)
CN202110214365.4A 2012-11-06 2013-11-06 用作药物或膳食活性成分的多孔二氧化硅材料 Pending CN113069467A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261723019P 2012-11-06 2012-11-06
US61/723,019 2012-11-06
CN201380069421.3A CN105188720A (zh) 2012-11-06 2013-11-06 用作药物或膳食活性成分的多孔硅材料

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CN201380069421.3A Division CN105188720A (zh) 2012-11-06 2013-11-06 用作药物或膳食活性成分的多孔硅材料

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CN113069467A true CN113069467A (zh) 2021-07-06

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CN201380069421.3A Pending CN105188720A (zh) 2012-11-06 2013-11-06 用作药物或膳食活性成分的多孔硅材料

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US (2) US10695294B2 (https=)
EP (2) EP3892285A3 (https=)
JP (2) JP6421124B2 (https=)
CN (2) CN113069467A (https=)
AU (1) AU2013343565B2 (https=)
BR (1) BR112015010118A2 (https=)
CA (3) CA3024640A1 (https=)
CY (1) CY1124471T1 (https=)
DK (1) DK2916852T3 (https=)
ES (1) ES2878017T3 (https=)
HR (1) HRP20211036T1 (https=)
HU (1) HUE055017T2 (https=)
IL (1) IL238538B (https=)
LT (1) LT2916852T (https=)
PH (1) PH12015501010B1 (https=)
PL (1) PL2916852T3 (https=)
PT (1) PT2916852T (https=)
SI (1) SI2916852T1 (https=)
WO (1) WO2014072363A1 (https=)
ZA (1) ZA201502979B (https=)

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WO2024255777A1 (zh) * 2023-06-14 2024-12-19 厦门君德医药科技有限公司 一种接枝改性的介孔二氧化硅及其制备方法和应用

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US20200129444A1 (en) * 2017-07-13 2020-04-30 Carnegie Mellon University Method of Increasing Epithelial Permeability Using Nanoparticles
US20210085589A1 (en) * 2017-12-13 2021-03-25 L.I.Co.Rice S.R.L. Complex between lactoferrin and silica, process for the production thereof, and composition thereof for oral hygiene
GB201803363D0 (en) * 2018-03-01 2018-04-18 Sigrid Therapeutics Ab New materials and uses thereof
KR20210153080A (ko) * 2019-04-15 2021-12-16 나노로지카 에이비 퇴행성 신경질환, 뉴런 및 교세포의 치료, 예방 및/또는 퇴행 연기에 사용하기 위한 빈 다공성 입자.
CN110314151B (zh) * 2019-08-02 2020-06-02 深圳国佳产业基金管理有限公司 医用介孔二氧化硅材料及其应用
WO2021062538A1 (en) * 2019-09-30 2021-04-08 Zeroignition Technologies Inc. Thermally insulating and fire retardant material and method for making same
JP7578945B2 (ja) * 2020-10-27 2024-11-07 信越化学工業株式会社 イミダゾールシラン処理シリカからなる胆汁酸吸着剤
CN114195885B (zh) * 2022-01-12 2024-04-26 杭州隆基生物技术有限公司 一种单克隆抗体组合物提纯方法
CN118871077A (zh) 2022-02-04 2024-10-29 西格丽德治疗公司 包含多孔二氧化硅颗粒的口腔护理组合物
JP2025119063A (ja) 2022-04-28 2025-08-14 日本たばこ産業株式会社 無機多孔質材料を含む口腔用組成物
GB202212240D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New formulations and medical uses thereof
GB202212239D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New dietary supplements
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WO2014072363A1 (en) 2014-05-15
EP2916852B1 (en) 2021-04-14
PL2916852T3 (pl) 2021-11-02
CA3024640A1 (en) 2014-05-15
PH12015501010A1 (en) 2015-07-27
DK2916852T3 (en) 2021-05-10
US20150258028A1 (en) 2015-09-17
JP6421124B2 (ja) 2018-11-07
AU2013343565A1 (en) 2015-05-21
CA2890171A1 (en) 2014-05-15
JP2019023222A (ja) 2019-02-14
JP6752858B2 (ja) 2020-09-09
BR112015010118A2 (pt) 2017-07-11
PT2916852T (pt) 2021-06-15
CY1124471T1 (el) 2022-07-22
ZA201502979B (en) 2024-09-25
LT2916852T (lt) 2021-06-25
HUE055017T2 (hu) 2021-10-28
IL238538B (en) 2019-06-30
US12121612B2 (en) 2024-10-22
ES2878017T3 (es) 2021-11-18
CA3024460A1 (fr) 2018-11-15
IL238538A0 (en) 2015-06-30
HRP20211036T1 (hr) 2021-10-01
CN105188720A (zh) 2015-12-23
US10695294B2 (en) 2020-06-30
CA2890171C (en) 2019-01-22
US20200390703A1 (en) 2020-12-17
SI2916852T1 (sl) 2021-08-31
EP2916852A1 (en) 2015-09-16
EP3892285A3 (en) 2021-11-17
AU2013343565B2 (en) 2018-07-26
EP3892285A2 (en) 2021-10-13
PH12015501010B1 (en) 2023-10-20
JP2015536939A (ja) 2015-12-24

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