CN112999250A - 一种中药冻干饮片的制备方法 - Google Patents
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Abstract
本发明属于中药饮片制备技术领域，公开一种中药冻干饮片的制备方法，包括如下步骤：(1)将中药经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；(2)将切好的片送入‑30～‑45℃下冷冻1‑2h；(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中干燥；(4)将得到的充氮气包装，于‑3～20℃下储存，即得中药冻干饮片。本发明真空冷冻干燥方法，最大限度降低中药饮片中有效成分的损耗，制备的饮片美观、质地疏松，利于有效成分的溶出，保证饮片质量的稳定可控。
Description
技术领域
本发明属于中药饮片制备技术领域，具体涉及一种中药冻干饮片的制备方法。
背景技术
真空冷冻干燥是真空技术与冷冻技术相结合的新型干燥脱水技术。冷冻干燥的简单定义是：先将湿物质冷冻，然后把它放到较低的水蒸气分压下，使冰直接升华成蒸汽的干燥方法。与其他干燥手段不同，物料中的水是固态直接转变为气态的。真空冷冻技术能提高产品附加值并促进地方经济发展，符合国家提出的农副产品加工要讲究高水平、高起点、高标准的发展方向。由于应用真空冷冻干燥技术加工维持了低温状态，避免了高温对物料的影响，能够最大限度的保持原料的形态、色泽、品质，并且制品含水量低，复水性好，逐渐被人们运用于名贵中药材的加工干燥，如人参、西洋参、冬虫夏草、山药、枸杞、鹿茸、三七等的加工。
真空冷冻干燥是目前公认的干燥品质最佳的脱水方式，广泛应用于食品和制药行业，但中药饮片行业在该技术应用方面整体滞后，需要改进技术。
发明内容
本发明的目的在于克服现有技术的不足，提供一种中药冻干饮片的制备方法。
本发明解决上述技术问题的技术方案如下：
一种中药冻干饮片的制备方法，包括如下步骤：
(1)将中药经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-30～-45℃下冷冻1-2h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中干燥；
(4)将得到的充氮气包装，于-3～20℃下储存，即得中药冻干饮片
优选的，步骤(2)所述冷冻温度为-40℃。
优选的，步骤(3)所述真空冷冻干燥温度为40-55℃，真空度为20-23Pa。
优选的，步骤(3)所述真空冷冻温度为50℃，真空度为20Pa。
优选的，步骤(3)所述真空冷冻干燥时间为2-5h。
与现有技术相比，本发明专利的有益效果是：
(1)本发明方法简单，易于操作，易于干燥，保存药效，能有效满足临床对中药饮片的需要，提高临床疗效。
(2)本发明真空冷冻干燥方法，最大限度降低中药饮片中有效成分的损耗，制备的饮片美观、质地疏松，利于有效成分的溶出，保证饮片质量的稳定可控。
具体实施方式
以下对本发明的原理和特征进行描述，所举实例只用于解释本发明，并非用于限定本发明的范围。
实施例1
一种人参冻干饮片的制备方法，包括如下步骤：
(1)将人参经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-30℃下冷冻2h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在40℃、20Pa下干燥5h；
(4)将得到的充氮气包装，于-3℃下储存，即得人参冻干饮片。
实施例2
一种石斛冻干饮片的制备方法，包括如下步骤：
(1)将石斛经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-35℃下冷冻1.5h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在45℃、22Pa下干燥3h；
(4)将得到的充氮气包装，于5℃下储存，即得石斛冻干饮片。
实施例3
一种三七冻干饮片的制备方法，包括如下步骤：
(1)将三七经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-40℃下冷冻1h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在50℃、23Pa下干燥2h；
(4)将得到的充氮气包装，于20℃下储存，即得三七冻干饮片。
实施例4
一种肉桂冻干饮片的制备方法，包括如下步骤：
(1)将肉桂经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-45℃下冷冻1h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在55℃、23Pa下干燥2h；
(4)将得到的充氮气包装，于-1℃下储存，即得肉桂冻干饮片。
实施例5
一种薏苡仁冻干饮片的制备方法，包括如下步骤：
(1)将薏苡仁经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-40℃下冷冻1.5h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在50℃、20Pa下干燥3h；
(4)将得到的充氮气包装，于3℃下储存，即得薏苡仁冻干饮片。
实施例6
一种山药冻干饮片的制备方法，包括如下步骤：
(1)将山药经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-40℃下冷冻1.5h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在50℃、20Pa下干燥3h；
(4)将得到的充氮气包装，于3℃下储存，即得山药冻干饮片。
实施例7
一种鹿茸冻干饮片的制备方法，包括如下步骤：
(1)将山药经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-40℃下冷冻1.5h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中，在50℃、20Pa下干燥3h；
(4)将得到的充氮气包装，于3℃下储存，即得鹿茸冻干饮片。
以上所述仅是本发明的优选实施方式，应当理解本发明并非局限于本文所披露的形式，不应看作是对其他实施例的排除，而可用于各种其他组合、修改和环境，并能够在本文所述构想范围内，通过上述教导或相关领域的技术或知识进行改动。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (5)
1.一种中药冻干饮片的制备方法，其特征在于：包括如下步骤：
(1)将中药经过挑拣清洗，清洗干净后切成厚度为0.1～0.2cm片；
(2)将切好的片送入-30～-45℃下冷冻1-2h；
(3)将步骤(2)冷冻后的切片置于真空冷冻干燥设备中干燥；
(4)将得到的充氮气包装，于-3～20℃下储存，即得中药冻干饮片。
2.根据权利要求1所述的中药冻干饮片的制备方法，其特征在于：步骤(2)所述冷冻温度为-40℃。
3.根据权利要求1所述的中药冻干饮片的制备方法，其特征在于：步骤(3)所述真空冷冻干燥温度为40-55℃，真空度为20-23Pa。
4.根据权利要求1所述的中药冻干饮片的制备方法，其特征在于：步骤(3)所述真空冷冻干燥温度为50℃，真空度为20Pa。
5.根据权利要求1所述的中药冻干饮片的制备方法，其特征在于：步骤(3)所述真空冷冻干燥时间为2-5h。
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| CN106038630A (zh) * | 2016-07-26 | 2016-10-26 | 河南中医学院 | 一种牛膝饮片的炮制方法 |
| CN107638517A (zh) * | 2016-07-21 | 2018-01-30 | 江西本草天工生物技术有限公司 | 一种天麻冻干饮片工艺制备方法 |
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| CN107638517A (zh) * | 2016-07-21 | 2018-01-30 | 江西本草天工生物技术有限公司 | 一种天麻冻干饮片工艺制备方法 |
| CN106038630A (zh) * | 2016-07-26 | 2016-10-26 | 河南中医学院 | 一种牛膝饮片的炮制方法 |
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