CN112998114A - Production process of polygonatum tea polyphenol tablet candy - Google Patents

Production process of polygonatum tea polyphenol tablet candy Download PDF

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Publication number
CN112998114A
CN112998114A CN202110413066.3A CN202110413066A CN112998114A CN 112998114 A CN112998114 A CN 112998114A CN 202110413066 A CN202110413066 A CN 202110413066A CN 112998114 A CN112998114 A CN 112998114A
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Prior art keywords
powder
fine powder
extract
tea polyphenol
mixing
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Chinese (zh)
Inventor
周雪
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Harbin Wuzitang Pharmaceutical Co ltd
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Harbin Wuzitang Pharmaceutical Co ltd
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Priority to CN202110413066.3A priority Critical patent/CN112998114A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/48Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a production process of a rhizoma polygonati tea polyphenol tablet candy, belonging to the technical field of tablet candies and comprising the following steps: s1: preparing a material; s2: sieving; s3: weighing; s4: mixing; s5: granulating; s6: drying; s7: finishing the grains; s8: totally mixing; s9: tabletting; s10: coating; s11: internally wrapping; s2: checking; the radix puerariae extract in the polygonatum tea polyphenol tablet candy can effectively reduce blood sugar and blood fat, the polygonatum extract can reduce blood viscosity and enhance the autoimmune function of a human body, has a direct removing effect on oxygen radicals and has obvious anti-aging and anti-aging effects, the gardenia extract has the effects of relieving diarrhea, easing pain, benefiting gallbladder, resisting inflammation, treating soft tissue injury, inhibiting gastric secretion, reducing pancreatic amylase and the like, the whole efficacy of the polygonatum tea polyphenol tablet candy can be effectively improved due to the composition of various raw materials, and the polygonatum tea polyphenol tablet candy can be accepted by the public more, so that the popularization speed in the market is accelerated.

Description

Production process of polygonatum tea polyphenol tablet candy
Technical Field
The invention belongs to the technical field of tabletting candies, and particularly relates to a production process of a polygonatum tea polyphenol tabletting candy.
Background
The tablet candy is also called powder candy or tablet candy, also commonly called soda candy, which is a mixture formed by using refined sugar powder as a main body, adding fillers such as milk powder, spices and the like and binders such as starch syrup, dextrin, gelatin and the like, and granulating and tabletting.
The production raw materials of the tablet candy on the market are simple, the whole efficacy is poor, and the tablet candy is difficult to rapidly popularize on the market.
Disclosure of Invention
To solve the problems set forth in the background art described above. The invention provides a production process of a polygonatum tea polyphenol tablet candy, which has the characteristics of improving the overall efficacy of the polygonatum tea polyphenol tablet candy, being more acceptable to the public and accelerating the popularization speed in the market.
In order to achieve the purpose, the invention provides the following technical scheme: a production process of a rhizoma polygonati tea polyphenol tablet candy comprises the following steps:
s1: preparing the material
Preparing buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder, tea polyphenol powder, magnesium stearate powder, coating powder, 85% ethanol and 70% ethanol;
s2: sieving
Respectively sieving buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder and tea polyphenol powder with a 80-mesh sieve to obtain buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder and tea polyphenol fine powder for later use;
s3: weighing machine
Weighing buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder, tea polyphenol fine powder, magnesium stearate powder and coating powder according to the feeding amount for later use;
s4: mixing
Putting the weighed fine powder of the buckwheat extract, the fine powder of the green tea extract, the fine powder of the kudzu root extract, the fine powder of the rhizoma polygonati extract, the fine powder of the gardenia extract, the fine powder of the lactose, the fine powder of the corn starch, the fine powder of the microcrystalline cellulose, the fine powder of the silicon dioxide and the fine powder of the tea polyphenol into a mixer, mixing for 10min, passing through a 40-mesh sieve after mixing, and continuously mixing for 20min to uniformly mix the materials to prepare mixed powder;
s5: granulating
Adding 85% ethanol into the mixed powder, stirring to obtain soft material, granulating with 20 mesh sieve to obtain wet granule;
s6: drying
Drying the wet granules to obtain dry granules;
s7: whole grain
Granulating the dried granules with a 20-mesh sieve to obtain granules;
s8: total mixing
Placing the whole granules in a mixer, adding magnesium stearate powder, and mixing for 15min to obtain total mixed granules;
s9: tabletting
Tabletting the total mixed particles;
s10: coating film
Preparing coating solution with solid content of 8% from coating powder with 70% ethanol, coating with film, and increasing the theoretical weight of tablet core by 3% to obtain coated tablet;
s11: inner bag
Respectively filling the coated tablets into oral solid medicinal high-density polyethylene bottles according to requirements, completing the split charging, placing 1 desiccant in each bottle, and sealing the oral solid medicinal high-density polyethylene bottles;
s2: examination of
Warehousing and checking to obtain a finished product after the product is qualified.
Further in the present invention, in the step S6, the drying temperature of the wet granules is in the range of 50 to 60 ℃.
Further in the present invention, in the step S6, the moisture content of the dried granules after drying is less than or equal to 5%.
Further, in the present invention, in the step S9, the tablet weight after tabletting is 1000mg, and the difference range of the tablet weight is 1000mg + 5%.
Further in the present invention, in step S11, the oral solid pharmaceutical high density polyethylene bottle used should meet YBB00122002 standard.
Further, in the present invention, in the step S11, the desiccant used is a pharmaceutical solid paper bagged silica gel desiccant meeting the YBB00122005 standard.
Compared with the prior art, the invention has the beneficial effects that:
1. the invention relates to a rhizoma polygonati tea polyphenol tablet candy which is prepared from raw materials of buckwheat extract, green tea extract, kudzu root extract, rhizoma polygonati extract and gardenia extract, wherein the kudzu root extract contains flavonoid compounds and can effectively reduce blood sugar and blood fat, the rhizoma polygonati extract contains copper chloride and natural polysaccharide, the copper chloride can promote the vasodilatation in human body, accelerate the blood circulation and reduce the blood viscosity, the natural polysaccharide can promote the regeneration of immune cells in human body and enhance the autoimmune function of human body, the polysaccharide can inhibit the generation of spontaneous and induced lipid peroxidation product malondialdehyde in the human body, has direct clearing effect on oxygen free radicals and has obvious anti-aging effect, the gardenia extract contains jasminoidin which has the functions of slow diarrhea, analgesia, cholagogue, anti-inflammation, treating soft tissue injury, inhibiting gastric secretion, reducing pancreatic amylase and the like, the composition of various raw materials can effectively improve the overall efficacy of the Huangjing tea polyphenol tablet candy, and can be accepted by the public, thereby accelerating the popularization speed in the market.
2. The auxiliary materials of the flavonol tea polyphenol tablet candy of the invention are added with tea polyphenol which contains chemical substances of polyphenol hydroxyl, and the hydroxyl in the structure can provide active hydrogen to inactivate free radicals, thus having stronger antioxidant activity, having remarkable anti-aging and anti-tumor effects, simultaneously the tea polyphenol can comprehensively adjust blood fat, in particular reduce the content of serum TG, TC and low-density lipoprotein cholesterol, increase HDL-C and reduce blood fat, and the tea polyphenol has natural, low-toxicity and high-efficiency antiviral effects, can resist pathogenic microorganisms such as influenza virus, rotavirus and bovine coronavirus, Human Immunodeficiency Virus (HIV), adenovirus, EB virus and Human Papilloma Virus (HPV), and further improves the integral efficacy of the flavonol tea polyphenol candy by tablet.
Drawings
Fig. 1 is a production process diagram of the Huangjing tea polyphenol tablet candy of the invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Referring to fig. 1, the present invention provides the following technical solutions: a production process of a rhizoma polygonati tea polyphenol tablet candy comprises the following steps:
s1: preparing the material
Preparing buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder, tea polyphenol powder, magnesium stearate powder, coating powder, 85% ethanol and 70% ethanol;
s2: sieving
Respectively sieving buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder and tea polyphenol powder with a 80-mesh sieve to obtain buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder and tea polyphenol fine powder for later use;
s3: weighing machine
Weighing buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder, tea polyphenol fine powder, magnesium stearate powder and coating powder according to the feeding amount for later use;
s4: mixing
Putting the weighed fine powder of the buckwheat extract, the fine powder of the green tea extract, the fine powder of the kudzu root extract, the fine powder of the rhizoma polygonati extract, the fine powder of the gardenia extract, the fine powder of the lactose, the fine powder of the corn starch, the fine powder of the microcrystalline cellulose, the fine powder of the silicon dioxide and the fine powder of the tea polyphenol into a mixer, mixing for 10min, passing through a 40-mesh sieve after mixing, and continuously mixing for 20min to uniformly mix the materials to prepare mixed powder;
s5: granulating
Adding 85% ethanol into the mixed powder, stirring to obtain soft material, granulating with 20 mesh sieve to obtain wet granule;
s6: drying
Drying the wet granules to obtain dry granules;
s7: whole grain
Granulating the dried granules with a 20-mesh sieve to obtain granules;
s8: total mixing
Placing the whole granules in a mixer, adding magnesium stearate powder, and mixing for 15min to obtain total mixed granules;
s9: tabletting
Tabletting the total mixed particles;
s10: coating film
Preparing coating solution with solid content of 8% from coating powder with 70% ethanol, coating with film, and increasing the theoretical weight of tablet core by 3% to obtain coated tablet;
s11: inner bag
Respectively filling the coated tablets into oral solid medicinal high-density polyethylene bottles according to requirements, completing the split charging, placing 1 desiccant in each bottle, and sealing the oral solid medicinal high-density polyethylene bottles;
s2: examination of
Warehousing and checking to obtain a finished product after the product is qualified.
Specifically, in step S6, the drying temperature range of the wet granules is 50 ℃.
Specifically, in step S6, the moisture content of the dried pellets after drying is less than 5%.
Specifically, in step S9, the tablet weight after tabletting was 1000mg, and the difference in tablet weight was 1000mg + 5%.
Specifically, in step S11, the oral solid pharmaceutical high density polyethylene bottle is required to meet YBB00122002 standard.
Specifically, in step S11, the desiccant used is a pharmaceutical solid paper bagged silica gel desiccant meeting the YBB00122005 standard.
Example 2
Referring to fig. 1, the present invention provides the following technical solutions: a production process of a rhizoma polygonati tea polyphenol tablet candy comprises the following steps:
s1: preparing the material
Preparing buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder, tea polyphenol powder, magnesium stearate powder, coating powder, 85% ethanol and 70% ethanol;
s2: sieving
Respectively sieving buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder and tea polyphenol powder with a 80-mesh sieve to obtain buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder and tea polyphenol fine powder for later use;
s3: weighing machine
Weighing buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder, tea polyphenol fine powder, magnesium stearate powder and coating powder according to the feeding amount for later use;
s4: mixing
Putting the weighed fine powder of the buckwheat extract, the fine powder of the green tea extract, the fine powder of the kudzu root extract, the fine powder of the rhizoma polygonati extract, the fine powder of the gardenia extract, the fine powder of the lactose, the fine powder of the corn starch, the fine powder of the microcrystalline cellulose, the fine powder of the silicon dioxide and the fine powder of the tea polyphenol into a mixer, mixing for 10min, passing through a 40-mesh sieve after mixing, and continuously mixing for 20min to uniformly mix the materials to prepare mixed powder;
s5: granulating
Adding 85% ethanol into the mixed powder, stirring to obtain soft material, granulating with 20 mesh sieve to obtain wet granule;
s6: drying
Drying the wet granules to obtain dry granules;
s7: whole grain
Granulating the dried granules with a 20-mesh sieve to obtain granules;
s8: total mixing
Placing the whole granules in a mixer, adding magnesium stearate powder, and mixing for 15min to obtain total mixed granules;
s9: tabletting
Tabletting the total mixed particles;
s10: coating film
Preparing coating solution with solid content of 8% from coating powder with 70% ethanol, coating with film, and increasing the theoretical weight of tablet core by 3% to obtain coated tablet;
s11: inner bag
Respectively filling the coated tablets into oral solid medicinal high-density polyethylene bottles according to requirements, completing the split charging, placing 1 desiccant in each bottle, and sealing the oral solid medicinal high-density polyethylene bottles;
s2: examination of
Warehousing and checking to obtain a finished product after the product is qualified.
Specifically, in step S6, the drying temperature range of the wet granules is 60 ℃.
Specifically, in step S6, the moisture content of the dried pellets after drying is equal to 5%.
Specifically, in step S9, the tablet weight after tabletting was 1000mg, and the difference in tablet weight was 1000mg + 5%.
Specifically, in step S11, the oral solid pharmaceutical high density polyethylene bottle is required to meet YBB00122002 standard.
Specifically, in step S11, the desiccant used is a pharmaceutical solid paper bagged silica gel desiccant meeting the YBB00122005 standard.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A production process of a rhizoma polygonati tea polyphenol tablet candy is characterized by comprising the following steps:
s1: preparing the material
Preparing buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder, tea polyphenol powder, magnesium stearate powder, coating powder, 85% ethanol and 70% ethanol;
s2: sieving
Respectively sieving buckwheat extract powder, green tea extract powder, kudzu root extract powder, sealwort extract powder, gardenia extract powder, lactose powder, corn starch, microcrystalline cellulose powder, silicon dioxide powder and tea polyphenol powder with a 80-mesh sieve to obtain buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder and tea polyphenol fine powder for later use;
s3: weighing machine
Weighing buckwheat extract fine powder, green tea extract fine powder, kudzu root extract fine powder, sealwort extract fine powder, gardenia extract fine powder, lactose fine powder, corn starch fine powder, microcrystalline cellulose fine powder, silicon dioxide fine powder, tea polyphenol fine powder, magnesium stearate powder and coating powder according to the feeding amount for later use;
s4: mixing
Putting the weighed fine powder of the buckwheat extract, the fine powder of the green tea extract, the fine powder of the kudzu root extract, the fine powder of the rhizoma polygonati extract, the fine powder of the gardenia extract, the fine powder of the lactose, the fine powder of the corn starch, the fine powder of the microcrystalline cellulose, the fine powder of the silicon dioxide and the fine powder of the tea polyphenol into a mixer, mixing for 10min, passing through a 40-mesh sieve after mixing, and continuously mixing for 20min to uniformly mix the materials to prepare mixed powder;
s5: granulating
Adding 85% ethanol into the mixed powder, stirring to obtain soft material, granulating with 20 mesh sieve to obtain wet granule;
s6: drying
Drying the wet granules to obtain dry granules;
s7: whole grain
Granulating the dried granules with a 20-mesh sieve to obtain granules;
s8: total mixing
Placing the whole granules in a mixer, adding magnesium stearate powder, and mixing for 15min to obtain total mixed granules;
s9: tabletting
Tabletting the total mixed particles;
s10: coating film
Preparing coating solution with solid content of 8% from coating powder with 70% ethanol, coating with film, and increasing the theoretical weight of tablet core by 3% to obtain coated tablet;
s11: inner bag
Respectively filling the coated tablets into oral solid medicinal high-density polyethylene bottles according to requirements, completing the split charging, placing 1 desiccant in each bottle, and sealing the oral solid medicinal high-density polyethylene bottles;
s2: examination of
Warehousing and checking to obtain a finished product after the product is qualified.
2. The process for producing a rhizoma polygonati tea polyphenol tabletted candy according to claim 1, wherein the process comprises the following steps: in the step S6, the drying temperature range of the wet granules is 50 to 60 ℃.
3. The process for producing a rhizoma polygonati tea polyphenol tabletted candy according to claim 1, wherein the process comprises the following steps: in step S6, the moisture content of the dried pellets after drying is less than or equal to 5%.
4. The process for producing a rhizoma polygonati tea polyphenol tabletted candy according to claim 1, wherein the process comprises the following steps: in step S9, the tablet weight after tabletting was 1000mg, and the difference in tablet weight was 1000mg + 5%.
5. The process for producing a rhizoma polygonati tea polyphenol tabletted candy according to claim 1, wherein the process comprises the following steps: in the step S11, the oral solid medicinal high-density polyethylene bottle is required to meet the YBB00122002 standard.
6. The process for producing a rhizoma polygonati tea polyphenol tabletted candy according to claim 1, wherein the process comprises the following steps: in the step S11, the desiccant used is a medicinal solid paper bagged silica gel desiccant meeting the YBB00122005 standard.
CN202110413066.3A 2021-04-16 2021-04-16 Production process of polygonatum tea polyphenol tablet candy Pending CN112998114A (en)

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Publication number Priority date Publication date Assignee Title
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Application publication date: 20210622