CN101589806A - A kind of solid low-energy food that is rich in dietary fiber and polyethylene glycol and preparation method thereof - Google Patents
A kind of solid low-energy food that is rich in dietary fiber and polyethylene glycol and preparation method thereof Download PDFInfo
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- CN101589806A CN101589806A CNA2008101136520A CN200810113652A CN101589806A CN 101589806 A CN101589806 A CN 101589806A CN A2008101136520 A CNA2008101136520 A CN A2008101136520A CN 200810113652 A CN200810113652 A CN 200810113652A CN 101589806 A CN101589806 A CN 101589806A
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Abstract
The invention discloses a kind of low energy food with health care or food substitute and its production and use, it is to form with materials such as dietary fiber, polyethylene glycol, proteins,vitamins,minerals, food additives, flavor enhancement, adhesives, can be made into multiple edible formulation eats, can effectively prevent or alleviate overnutrition, reduce the incidence of disease of body weight, reduction cardiovascular and cerebrovascular disease, tumour, diabetes etc., have good applied value and market prospects.
Description
[technical field]
The present invention relates to a kind of solid low-energy food that is rich in dietary fiber and preparation method thereof, particularly contain solid low-energy food of dietary fiber and polyethylene glycol and preparation method thereof.
[background technology]
Modern medicine is commonly referred to as malnutrition with overnutrition and subalimentation, and long-term nutrition not good general causes multiple metabolic disease.At present, the improper disease that causes of overnutrition and life style has become the No.1 killer who threatens human health, and various fatal chronic metabolic disease significantly rise as incidences of disease such as obesity, hypertension, coronary heart disease, diabetes, colorectal cancers.The dietary fiber insufficiency of intake is one of key factor of its morbidity.
Dietary fiber is meant the edible vegetalitas composition that can not digest and assimilate the human small intestine and the summation of similar material thereof, mainly comprises cellulose, hemicellulose, pectin and hydrophilic colloid material, as compositions such as natural gum, algal polysaccharides; The lignin that also comprises in the plant cell wall in addition being contained; The material that is decomposed by the human consumption enzyme not is as resistant starch, resistant dextrin, resistance compound sugar, modified cellulose, clayey, oligosaccharides and relevant on a small quantity composition, as paraffin paper, cutin, suberin etc.Dietary fiber has one or more physiological functions such as relaxing bowel, regulate control blood sugar concentration, reducing blood lipid.Dietary fiber is a kind of edible vegetalitas composition, but not animal component.Be divided into soluble dietary fiber (SDF) and soluble dietary fiber (IDF) according to its dissolubility in water.Soluble dietary fiber comprises hydrophilic colloid material and part hemicelluloses such as pectin, and soluble dietary fiber (IDF) comprises cellulose, lignin and part hemicellulose.
The dietary fiber molecule contains a lot of hydrophilic radicals, has very strong retention ability, and the surface has a lot of active groups simultaneously, can adsorb the noxious material organic compounds such as (endogenous toxin and heterotoxins) in chelating cholesterol, bile acid and the enteron aisle.More and more evidences shows that dietary fiber is one of needed by human composition that keeps health.Increase dietary cellulosic intake has benefit in many ways to human body, as preventing treating constipation, be beneficial to fat-reducing, the prevention colon and the carcinoma of the rectum, prevent and treat hemorrhoid, reducing blood fat, prevents coronary heart disease, improves diabetic symptom, prevents and treats gall stone, prevents breast cancer etc.
Anti-treating constipation is the in use universally recognized beneficial functions of dietary fiber, it makes moisture content wherein be not easy to be absorbed by the suction volumetric expansion, thereby stimulate enterocinesia to reduce food time of staying in enteron aisle, dietary fiber in large intestine through bacterial fermentation, directly absorb the moisture content in the fiber, make the stool deliquescing, and then produce defecating feces excretion.Yet in actual use, people have but ignored the side effect that dietary fiber causes constipation.When the intake of dietary fiber is big, when particularly disposable absorption restrains greater than 10, can produce constipation, abdominal distension, stomachache, more rare side effect has the interior fiber coprolite that forms of enteron aisle to cause intestinal obstruction, the opposite effect that the defaecation that self is had with dietary fiber occurs and prevent treating constipation, these side effects occurrence rate in the patient of the elderly or skeletonize is higher.The main cause that causes these side effects is because dietary fiber is stronger to the enterocinesia spread effect of the enteron aisle more than the colon, spread effect to enterocinesia weakens behind the colon and enter, make dietary fiber dehydration in colon, accumulation and bacterial fermentation aerogenesis, cause abdominal distension, constipation, even formation fiber coprolite causes intestinal obstruction.At present, along with increasing substantially of living standard, deep variation has taken place in people's diet structure, the maximum characteristics of this variation are to be main progressively to carry out the transition to vegetalitas and animal food (meat, egg, breast) develops simultaneously with the plant food by the past, even based on the diet structure of animal food.The intake of the total dietary fiber that U.S. FDA is recommended is 30-35g every day, according to Chinese Soclety of Nutrition's promulgation in 2000 Chinese residents Dietary Reference Intakes regulation, everyone dietary fiber every day intake is 30.2g, yet according to investigation, China's one-tenth dietary fiber of everyone every day for each person is 13.3g, and the cellulose amount of eating is obviously on the low side.Therefore, the magnitude of recruitment of China adult dietary fiber every day should as adopting disposable supply every day, be taken about 20 grams for a long time, then can cause constipation.
Polyethylene glycol (PEG) is with oxirane and water or the spent glycol less class water soluble polyether of molecular weight that obtains of addition polymerization progressively, it is the pharmaceutic adjuvant that many NFs such as Chinese Pharmacopoeia and English, U.S. record, in preparation, use very extensive, polyethylene glycol is extensive use of clinical as the permeability laxatives simultaneously, can make most of chronic functional constipation patient's stool shape, number of times recover normal, main symptom of digestive tract disappears, and do not have obvious adverse reaction and take place, long-term safe in utilization effective, clinical Macrogol 4000 commonly used.Therefore, add polyethylene glycol in dietary fiber food, for improving the quality of products, increase the compliance that product uses, the side effect that reduces the product use has important effect.
[summary of the invention]
The purpose of this invention is to provide a kind of solid low-energy food that is rich in dietary fiber and polyethylene glycol and preparation method thereof and as the application of food and health food with health care.
For achieving the above object, the present invention has adopted following technical scheme.
A kind of solid low-energy food with health care of the present invention is by including dietary fiber and polyethylene glycol is formed, wherein the content of dietary fiber is selected 30%-95% by weight, preferred 30%-80%, more preferably 30%-70%, the content of polyethylene glycol is the 10%-50% of contained dietary fiber amount by weight, preferred 15-40% more selects 20%-35%.The absorption of high dose causes the effect characteristics of constipation because dietary fiber has low dosage absorption defaecation, therefore, polyethylene glycol is to add in by weight ratio in described solid low-energy food, the intake of the intake of defaecation ease constipation functional mass and dietary fiber forms positive correlation like this, the absorption that is dietary fiber is many more, then the absorption of defaecation ease constipation functional mass is also many more, in the time of just can producing the absorption of dietary fiber low dosage by both ratios of suitable adjustment, the polyethylene glycol intake is less than effect dosage, still keep the normal bowel relaxing functions of dietary fiber, and when the dietary fiber high dose is taken in, the polyethylene glycol intake also increases thereupon, reach the effect dosage level, and then resisted the side effect that dietary fiber causes constipation effectively.The ratio of both concrete addings is with the kind of kind, the characteristic of the dietary fiber that is adopted and the polyethylene glycol that adopted and characteristic decision.
Described polyethylene glycol is selected from one or more the mixture of molecular weight in the polyethylene glycol of 2000-20000, preferred Macrogol 4000 and Macrogol 6000.
The present invention creatively adds polyethylene glycol in the solid food as the dietary fiber replenishers, take in the side effect of constipation induced in a large number in order to overcome dietary fiber.At present, the report that existing many pieces of relevant dietary fibers and defaecation ease constipation functional mass share, dietary cellulosic is arranged, saline cistanche, Radix Angelicae Sinensis etc. combination (Chinese patent application number 03105221.5), the combination (Chinese patent application number 03152858.9) of dietary fiber and almond powder etc. is arranged, the combination (Granted publication 1294849C) of dietary fiber and inulin etc. is arranged, the combination (Chinese patent application number 00110105.6) of wheat aleurone (a kind of dietary fiber) and folium sennae etc. is arranged, dietary fiber and aloe etc. share (Yang Zhenge etc., the functions of loosening bowel relieving constipation effect observation of high fibre diet. Hygiene Toxicology magazine 2004; 18 (2): 128-129).But these reports are essentially different with the related content of this paper: 1) Special attention will be given to of the present invention dietary fiber have the lateral reactivity that causes constipation, and then add polyethylene glycol to overcome the lateral reactivity that dietary fiber causes constipation; And bibliographical information does not notice that dietary fiber has the lateral reactivity that causes constipation, but with dietary fiber as a kind of material with defaecation ease constipation activity, share to improve the effect of relaxing bowel of prepared preparation with other materials with defaecation ease constipation activity; 2) emphasis of the present invention is to produce a kind of low-energy solid food, main purpose is the deficiency that the complementary diets fiber is taken in, therefore in the preparation content of dietary fiber all more than 30%, and the dietary fiber content of the described preparation of bibliographical information all is lower than 25%, the ease constipation of defaecation simultaneously is again as its main effect, the taking dose that requires is less, as being used instead, it is the dietary fiber replenishers, then take in a large number, can cause diarrhoea, therefore, can not use, be essentially different with the present invention as the replenishers of dietary fiber.3) to share dietary fiber and polyethylene glycol with preparation first be the health food of main effect with the dietary fiber replenishers in the present invention.
Described dietary fiber comprises cellulose, hemicellulose, pectin, lignin and hydrophilic colloid material, as compositions such as natural gum, algal polysaccharides and the material that do not decomposed by the human consumption enzyme, as resistant starch, resistant dextrin, resistance compound sugar, modified cellulose, clayey, oligosaccharides and relevant on a small quantity composition, as paraffin paper, cutin, suberin etc.Described solid low-energy food includes additives except that dietary fiber and polyethylene glycol.Described additives be selected from glucide, lipid material, proteins,vitamins,minerals, food additives, flavor enhancement and food with and pharmaceutical formulation dressing in one or more mixture.
Owing to contain a lot of hydrophilic radicals in the dietary fiber chemical constitution, have very strong dilatancy and retention ability, its dilatancy of the dietary fiber of separate sources and retention ability difference are very big, are 54 milliliters/gram as its expansive force of dietary fiber that extracts from sea-tangle, and retention ability is 3201%; Its expansive force of the dietary fiber that extracts from wheat straw and retention ability are respectively 4.7～6.9 milliliters/gram, 740～880%; The cmaize peel food fibre expansive force is 18.2 a milliliters/gram, and retention ability is 930%.The retentiveness of dietary fiber and water swelling, easily cause satiety, simultaneously, because dietary fiber also can influence digesting and assimilating in vivo such as the composition that can utilize carbohydrate, make the people be difficult for producing hunger, therefore, take dietary fiber in right amount, can effectively prevent or alleviate overnutrition, prevention of obesity disease, reduce body weight, reduce the incidence of disease of cardiovascular and cerebrovascular disease, tumour, diabetes etc.Solid low-energy food of the present invention can be made into the multiple solid pharmaceutical preparation of taking that is beneficial to, its preparation type includes but not limited to tablet, capsule, granule, pill, powder or cakes, and wherein tablet has ordinary tablet, buccal tablet, chewable tablets, dispersing tablet, effervescent tablet etc.; Capsule has hard shell capsules, soft capsule etc.; Granule has plain particles, suspended particulate, effervescence granular etc.; Pill has piller, dripping pill, sugar-pill etc.; Dessert, biscuit, fast food rod etc. between cakes such as instant type meal.Described preparation is preparation type commonly used in food and the pharmaceutical industries, can prepare by conventional method.
Described food reduces because dietary fiber is taken in the food of side effect of constipation induced and the purposes in the health products in a large number in preparation.
The preparation of low energy food of the present invention may further comprise the steps:
1) polyethylene glycol is mixed with dietary fiber, make the mixture of dietary fiber and polyethylene glycol;
2) in mixture, add necessary additives;
3) make and be rich in the dietary fiber food particle through bonding, granulation, drying;
4) on former, make different dosage form the low energy food that is rich in dietary fiber;
5) packing has been equipped with edible.
[beneficial effect]
1) the present invention creatively adds polyethylene glycol in dietary fiber, has overcome that dietary fiber is eaten and forms side effect such as fiber coprolite in the constipation that causes, abdominal distension, stomachache and the more rare enteron aisle.It is conventionally believed that dietary fiber has defaecation, promotion enterocinesia, the anti-effect that treats constipation, be one of the food that is used to relax bowel and main functional component of health food, but in actual applications and ignored dietary fiber and can cause side effects such as constipation, abdominal distension even intestinal obstruction.This class side effect is often relevant with absorption dosage.The present invention utilizes dietary fiber to have that low dosage is taken in defaecation dexterously and the absorption of high dose causes the effect characteristics of constipation, in described solid low energy food, add polyethylene glycol in proportion, make the intake of defaecation ease constipation functional mass and the intake of dietary fiber form positive correlation, when producing the absorption of dietary fiber low dosage by both ratios of suitable adjustment, the polyethylene glycol intake is less than effect dosage, still keep the normal bowel relaxing functions of dietary fiber, and when the dietary fiber high dose is taken in, the polyethylene glycol intake also increases thereupon, reach the effect dosage level, and then resisted the side effect that dietary fiber causes constipation effectively.This increases the compliance that product uses for improving the quality of products, and the side effect that the minimizing product uses etc. has important effect.
2) make the intake of dietary fiber every day reach the effect dosage level.The dietary fiber amount of eating of at present Chinese everyone every day is 13.3 grams, issues the intake of everyone 30.2 grams every day of Chinese residents Dietary Reference Intakes regulation in 2000 far below Chinese Soclety of Nutrition.The present invention has creatively designed the solid food that is rich in dietary fiber and polyethylene glycol, and the deficiency of complementary diets fiber intake effectively helps preventing and reducing the incidence of disease of cardiovascular and cerebrovascular disease, tumour, diabetes, gall stone etc.
3) absorption of minimizing anakinetomer.Dietary fiber is that a class can not be absorbed by human consumption, but have the people of allowing and produce multiple efficacies such as the sense of satisfying, promotion enterocinesia, quickening drainage, reduction cholesterolemia, therefore, edible solid low-energy food of the present invention can effectively reduce the absorption of anakinetomer, produces the effect of keeping or reduce body weight.
4) easy to use.Product of the present invention is convenient, the easy to carry common formulations of multiple eating, for the use of product provide more easily by way of.
5) production technology is simply cheap, is beneficial to very much marketing.
Therefore, the technology of the present invention has important health care meaning and good prospects for application.
[specific implementation method]
By following concrete embodiment, can further understand the present invention, but following example not a limitation of the invention.
Embodiment-interpolation polyethylene glycol uses the influence of compliance to the solid low energy food that is rich in dietary fiber
Raw material: purity is 80% dietary fiber (abbreviation dietary fiber), Macrogol 4000, Macrogol 6000, cetomacrogol 1000 0, sorbierite, galactolipin fructoside, inulin, soyabean protein powder, multivitamin mineral matter composite sheet, superfine silica gel powder, starch
Method: get dietary fiber and add polyethylene glycol, soyabean protein powder, multivitamin mineral matter composite sheet, superfine silica gel powder and starch, mixing is pulverized; The ethanolic solution of preparation 40%, and with its preparation 10%PVPk30 solution, mix and make adhesive; In the dietary fiber mixture, add adhesive and make softwood, 20 mesh sieves are granulated, 45～50 ℃ of oven dry; Get dried particle, the whole grain of 20 mesh sieves adds weight ratio and is 3% dolomol, and mixing is pressed into the solid low energy food that is rich in dietary fiber of 1.03 gram/sheets with tablet press machine, packs with 30 slices/bag then, stores in order to eating.Preparation has four kinds of prescriptions, and is specific as follows:
1, gross weight 2000 grams, wherein dietary fiber 1200 grams, soyabean protein powder 200 grams, multivitamin mineral matter composite sheet 100 grams, superfine silica gel powder 100 grams, starch 400 grams
2, gross weight 2000 grams, wherein dietary fiber 1200 grams, Macrogol 4000 240 grams, soyabean protein powder 200 grams, multivitamin mineral matter composite sheet 100 grams, superfine silica gel powder 100 grams, starch 160 grams
3, gross weight 2000 grams, wherein dietary fiber 1200 grams, Macrogol 6000 240 grams, soyabean protein powder 200 grams, multivitamin mineral matter composite sheet 100 grams, superfine silica gel powder 100 grams, starch 160 grams
4, gross weight 2000 grams, wherein dietary fiber 1200 grams, cetomacrogol 1000 0 240 grams, soyabean protein powder 200 grams, multivitamin mineral matter composite sheet 100 grams, superfine silica gel powder 100 grams, starch 160 grams
Choose trial volunteer's 32 examples, be divided into four groups, be respectively control group, 1 group of experimental preparation, 2 groups of experimental preparations, 3 groups of experimental preparations, take 30 grams (containing dietary fiber 14.4 grams) before dinner every day, drink water about 500 milliliters, chew clothes, normally have meal then with water mixing in the oral cavity.Took for two weeks continuously, the reaction of observing after the experimenter takes comprises indexs such as satiety, dining amount, physical exertion, stomachache, abdominal distension, constipation.
The results are shown in Table 1, in being rich in the solid low energy food of dietary fiber, add polyethylene glycol and can alleviate the constipation of dietary fiber due to eating effectively, improved the compliance that dietary fiber uses.
Table 1, interpolation polyethylene glycol use the influence of compliance to the solid low energy food that is rich in dietary fiber
Claims (8)
1, a kind of solid low-energy food as the dietary fiber replenishers is characterized in that containing in the described food dietary fiber and polyethylene glycol, and wherein the content of dietary fiber is 30%-95% by weight.
2, food according to claim 1, wherein polyethylene glycol is the 10%-50% of contained dietary fiber amount by weight.
3, food according to claim 1 is characterized in that described polyethylene glycol is that molecular weight is daltonian one or more the polyethylene glycol mixture of 2000-20000, preferred Macrogol 4000 and Macrogol 6000.
4, food according to claim 1 is characterized in that described food product packets contains additives.
5, food according to claim 1, the preparation type that it is characterized in that described food is tablet, capsule, granule, pill, powder or cakes.
6, food according to claim 4 is characterized in that described additives are selected from one or more the mixture in glucide, lipid material, proteins,vitamins,minerals, food additives, flavor enhancement and other the edible and pharmaceutical formulation dressing.
7, the described food of claim 1 reduces because dietary fiber is taken in the food of side effect of constipation induced and the purposes in the health products in a large number in preparation.
8. the preparation method of the food of claim 1 is characterized in that may further comprise the steps:
1) polyethylene glycol is mixed with dietary fiber, make the mixture of dietary fiber and polyethylene glycol;
2) in mixture, add necessary additives;
3) make and be rich in the dietary fiber food particle through bonding, granulation, drying;
4) on former, make different dosage form the low energy food that is rich in dietary fiber;
5) packing has been equipped with edible.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008101136520A CN101589806A (en) | 2008-05-29 | 2008-05-29 | A kind of solid low-energy food that is rich in dietary fiber and polyethylene glycol and preparation method thereof |
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| CNA2008101136520A CN101589806A (en) | 2008-05-29 | 2008-05-29 | A kind of solid low-energy food that is rich in dietary fiber and polyethylene glycol and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109475544A (en) * | 2016-03-29 | 2019-03-15 | 科罗纳里康赛普茨有限责任公司 | For treating the preparation of constipation |
| US11102998B1 (en) | 2017-08-25 | 2021-08-31 | The Hershey Company | Binders and methods of making and using the same |
| CN115737736A (en) * | 2022-11-10 | 2023-03-07 | 南京北极光生物科技有限公司 | Composition containing polyethylene glycol and bulking fiber and its use for relieving constipation and increasing defecation |
-
2008
- 2008-05-29 CN CNA2008101136520A patent/CN101589806A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109475544A (en) * | 2016-03-29 | 2019-03-15 | 科罗纳里康赛普茨有限责任公司 | For treating the preparation of constipation |
| US11102998B1 (en) | 2017-08-25 | 2021-08-31 | The Hershey Company | Binders and methods of making and using the same |
| CN115737736A (en) * | 2022-11-10 | 2023-03-07 | 南京北极光生物科技有限公司 | Composition containing polyethylene glycol and bulking fiber and its use for relieving constipation and increasing defecation |
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Open date: 20091202 |