CN107549822A - A kind of Semen Tritici aestivi fiber crude granule and preparation method thereof - Google Patents

A kind of Semen Tritici aestivi fiber crude granule and preparation method thereof Download PDF

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Publication number
CN107549822A
CN107549822A CN201710929352.9A CN201710929352A CN107549822A CN 107549822 A CN107549822 A CN 107549822A CN 201710929352 A CN201710929352 A CN 201710929352A CN 107549822 A CN107549822 A CN 107549822A
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CN
China
Prior art keywords
parts
tritici aestivi
semen tritici
aestivi fiber
crude granule
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CN201710929352.9A
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Chinese (zh)
Inventor
史月龙
吴英亮
汤静
吴坤林
刘文斌
孔玉琴
曾宋君
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Nanjing Tuai Bio Pharmaceutical Technology Co
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Nanjing Tuai Bio Pharmaceutical Technology Co
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Priority to CN201710929352.9A priority Critical patent/CN107549822A/en
Publication of CN107549822A publication Critical patent/CN107549822A/en
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Abstract

The invention discloses a kind of Semen Tritici aestivi fiber crude granule and preparation method thereof.The particle includes the following component counted in parts by weight:120 240 parts of Semen Tritici aestivi fiber element, 30 58 parts of ethanol, 12 24 parts of probiotics complexing agent, 45 56 parts of hydrophilic macromolecular compounds, 18 parts of maltodextrin, 13 parts of chitosan, 58 parts of ground rice, 25 parts of rilanit special, 12 28 parts of levulan, 30 50 parts of deionized water.Semen Tritici aestivi fiber element is dissolved in ethanol after being evaporated under reduced pressure at 30 50 DEG C, adds maltodextrin and levulan, stirring is spray-dried to obtain fine powder;Fine powder, hydrophilic macromolecular compounds, chitosan, ground rice, rilanit special and deionized water are mixed, after high speed shear, are granulated, is dried to the dry particl that water content is less than 1 2%, you can.Particle of the present invention not only improves constipation, can improve patient's immunity with coordinating intestines and stomach bacterium colony rich in abundant dietary fiber, lactic acid bacteria powder.

Description

A kind of Semen Tritici aestivi fiber crude granule and preparation method thereof
Technical field
The invention belongs to treat constipation technical field, and in particular to a kind of Semen Tritici aestivi fiber crude granule and preparation method thereof.
Background technology
With the development of society, growth in the living standard, people are to the quality requirement more and more higher for the material that absorbs nourishment, generation Boundary's health prevents regulation from absorbing food fiber 16-24g for each person every day.In terms of the food configuration in China, food fiber main source In vegetables, average content 3%, quantity is far from being enough.Most daily defecations of Healthy People once, if excrement is stagnant in enteric cavity Stay overlong time, interior moisture content so that excrement matter overdrying is hard, is not defecated, just for just more than 48-72h by excessive consumption It is secret.
The healthy food material with bowel relaxing functions is aloe, Chinese medicine, dietary fiber etc. in the market, and wherein meals are fine Tie up as main component.Dietary cellulosic be it is a kind of by the carbohydrate of human consumption health diet can not be made indispensable, Can be with prevention of cardiovascular disease, cancer, diabetes and other diseases.Dietary cellulosic is divided into insoluble diedairy fiber element and water Soluble dietary fiber element, Polydextrose can slow down digestion rate and most fast excretion of cholesterol, ensure to allow blood in blood Sugar and cholesterol can reduce the risk for suffering from intestinal cancer in desired grade, insoluble diedairy fiber element, while lower thin in alimentary canal The toxin of bacterium discharge.
Wheat bran is the byproduct of wheat processing, containing abundant dietary fiber, is nutrient needed by human, can improve Fibre composition in food, the excretion of fat and nitrogen can be promoted, there is increase satiety, Constipation, hypoglycemic and anticancer etc. Effect.The Chinese patent of application number 201310537202.5 discloses a kind of Semen Tritici aestivi fiber crude granule and preparation method thereof, at it Fang Wei:Semen Tritici aestivi fiber element 2730g, xylitol 270g, 95% ethanol solution of 4% hydroxypropyl methylcellulose are appropriate.Wheat of the present invention Cellulose grain insoluble diedairy fiber is to contain more than 75.0g in every 100 grams of particles, 2 times a day, each 3g, equivalent to daily Insoluble diedairy fiber 4.5g is supplemented, proves that there is bowel relaxing functions, total effective rate through animal experiment and human feeding trial 80.39%, but function is single, it is necessary to expand, in order to be taken for child.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of Semen Tritici aestivi fiber crude granule and its preparation side Method, the particle can not only improve constipation, can be improved with coordinating intestines and stomach bacterium colony rich in abundant dietary fiber, lactic acid bacteria powder Patient's immunity.
A kind of Semen Tritici aestivi fiber crude granule, including the following component counted in parts by weight:Semen Tritici aestivi fiber element 120-240 parts, second Alcohol 30-58 parts, probiotics complexing agent 12-24 parts, hydrophilic macromolecular compounds 45-56 parts, maltodextrin 1-8 parts, chitosan 1-3 parts, ground rice 5-8 parts, rilanit special 2-5 parts, levulan 12-28 parts, deionized water 30-50 parts.
Preferably, above-mentioned Semen Tritici aestivi fiber crude granule, including the following component counted in parts by weight:220 parts of Semen Tritici aestivi fiber element, 48 parts of ethanol, 35 parts of probiotics complexing agent, 50 parts of hydrophilic macromolecular compounds, 5 parts of maltodextrin, 1 part of chitosan, ground rice 7 Part, 3 parts of rilanit special, 25 parts of levulan, 40 parts of deionized water.
Preferably, the probiotics compounding machine is according to weight ratio by Bifidobacterium, Raman lactobacillus and lactobacillus acidophilus 1:2-4:2.
Preferably, the hydrophilic macromolecular compounds are formed by the condensation of polyurethane, oxirane and dextrin.
Preferably, the molecular weight of the chitosan is 1500-2000D.
The preparation method of above-mentioned Semen Tritici aestivi fiber crude granule, comprises the following steps:Step 1, each component is weighed;Step 2, will be small Wheat cellulose is dissolved in ethanol at 30-50 DEG C after vacuum distillation 20-40min, is added maltodextrin and levulan, is stirred Afterwards, it is spray-dried to obtain fine powder;Step 3, by fine powder, hydrophilic macromolecular compounds, chitosan, ground rice, rilanit special and go Ionized water mixes, and after high speed shear reaction 40-60min, is granulated, is dried to the dry particl that water content is less than 1-2%, you can.
Preferably, the pressure being evaporated under reduced pressure in step 1 is 0.8-1.58KPa.
Preferably, the speed of step 3 high speed shearing is 10000-12000rpm.
Compared with prior art, the present invention improves particle by the way that insoluble diedairy fiber and soluble dietary fiber are mixed Characteristic, then constipation cure rate is substantially increased with other component mixing granulations, gained Semen Tritici aestivi fiber crude granule, long-term clothes With that can be obviously improved user's stomach bacterium colony situation, so as to reach the effect of radical cure, and the particulate additive is few, after baby takes Also without influence.
Embodiment
The present invention is further described in detail below by specific embodiment.
Embodiment 1
A kind of Semen Tritici aestivi fiber crude granule, including the following component counted in parts by weight:Semen Tritici aestivi fiber element 120 parts, ethanol 30 Part, 12 parts of probiotics complexing agent, 45 parts of hydrophilic macromolecular compounds, 1 part of maltodextrin, 1 part of chitosan, 5 parts of ground rice, hydrogenation 2 parts of castor oil, 12 parts of levulan, 30 parts of deionized water.
Wherein, the probiotics compounding machine is 1 according to weight ratio by Bifidobacterium, Raman lactobacillus and lactobacillus acidophilus: 2:2.
The hydrophilic macromolecular compounds are formed by the condensation of polyurethane, oxirane and dextrin.
The molecular weight of the chitosan is 1500D.
The preparation method of above-mentioned Semen Tritici aestivi fiber crude granule, comprises the following steps:Step 1, each component is weighed;Step 2, will be small Wheat cellulose is dissolved in ethanol at 30 DEG C after vacuum distillation 20min, adds maltodextrin and levulan, after stirring, spraying Dry fine powder;Step 3, fine powder, hydrophilic macromolecular compounds, chitosan, ground rice, rilanit special and deionized water are mixed Close, after high speed shear reaction 40min, be granulated, be dried to the dry particl that water content is less than 1%, you can.
The pressure being evaporated under reduced pressure in step 1 is 0.8KPa.
The speed of step 3 high speed shearing is 10000rpm.
Embodiment 2
A kind of Semen Tritici aestivi fiber crude granule, including the following component counted in parts by weight:Semen Tritici aestivi fiber element 220 parts, ethanol 48 Part, 35 parts of probiotics complexing agent, 50 parts of hydrophilic macromolecular compounds, 5 parts of maltodextrin, 1 part of chitosan, 7 parts of ground rice, hydrogenation 3 parts of castor oil, 25 parts of levulan, 40 parts of deionized water.
Wherein, the probiotics compounding machine is 1 according to weight ratio by Bifidobacterium, Raman lactobacillus and lactobacillus acidophilus: 3:2.
The hydrophilic macromolecular compounds are formed by the condensation of polyurethane, oxirane and dextrin.
The molecular weight of the chitosan is 1800D.
The preparation method of above-mentioned Semen Tritici aestivi fiber crude granule, comprises the following steps:Step 1, each component is weighed;Step 2, will be small Wheat cellulose is dissolved in ethanol at 35 DEG C after vacuum distillation 30min, adds maltodextrin and levulan, after stirring, spraying Dry fine powder;Step 3, fine powder, hydrophilic macromolecular compounds, chitosan, ground rice, rilanit special and deionized water are mixed Close, after high speed shear reaction 45min, be granulated, be dried to the dry particl that water content is less than 1.8%, you can.
The pressure being evaporated under reduced pressure in step 1 is 1.25KPa.
The speed of step 3 high speed shearing is 11000rpm.
Embodiment 3
A kind of Semen Tritici aestivi fiber crude granule, including the following component counted in parts by weight:Semen Tritici aestivi fiber element 120-240 parts, second Alcohol 30-58 parts, probiotics complexing agent 12-24 parts, hydrophilic macromolecular compounds 45-56 parts, maltodextrin 1-8 parts, chitosan 1-3 parts, ground rice 5-8 parts, rilanit special 2-5 parts, levulan 12-28 parts, deionized water 30-50 parts.
Wherein, the probiotics compounding machine is 1 according to weight ratio by Bifidobacterium, Raman lactobacillus and lactobacillus acidophilus: 4:2.
The hydrophilic macromolecular compounds are formed by the condensation of polyurethane, oxirane and dextrin.
The molecular weight of the chitosan is 2000D.
The preparation method of above-mentioned Semen Tritici aestivi fiber crude granule, comprises the following steps:Step 1, each component is weighed;Step 2, will be small Wheat cellulose is dissolved in ethanol at 50 DEG C after vacuum distillation 40min, adds maltodextrin and levulan, after stirring, spraying Dry fine powder;Step 3, fine powder, hydrophilic macromolecular compounds, chitosan, ground rice, rilanit special and deionized water are mixed Close, after high speed shear reaction 60min, be granulated, be dried to the dry particl that water content is less than 2%, you can.
The pressure being evaporated under reduced pressure in step 1 is 1.58KPa.
The speed of step 3 high speed shearing is 12000rpm.
Comparative example 1
In addition to without levulan, remaining is the same as embodiment 2.
To testing for embodiment 1-3 and the Semen Tritici aestivi fiber crude granule of comparative example 1, the data obtained is as shown in the table.
Other physical and chemical indexs reach target level of product quality requirement.
Embodiment 1-3 Semen Tritici aestivi fiber crude granule is fed into small white mouse according to daily 20g, after continuous 30 days, in Mice Body Hematological indices, blood biochemistry index, internal organs absolute weight and dirty/body ratio compared with negative ui puts out to lease without significant difference, i.e., pair By inspection internal organs without obvious infringement.
Horse flower worked with kingfisher's feathers, female, 45 years old, prolonged constipation, the Semen Tritici aestivi fiber crude granule of embodiment 2 is taken, three times a day, a 2.5g, After taking one week, stool shape improves, and after taking 3 months, can be achieved to defecate once daily, and no pain.
He Jieru, female, 25 years old, it is pregnant 8 months, 4-7 days stool once, and defecate with bleeding every time, take reality The Semen Tritici aestivi fiber crude granule of example 2 is applied, three times a day, a 2.5g, after taking 5 days, stool is no longer stiff, can after taking 2 months Defecate once daily, and no pain.
Liu Liuliu, man, 2 years old, stool was dry and astringent, takes the Semen Tritici aestivi fiber crude granule of embodiment 2, once a day, a 1g, clothes After 2 days, stool is no longer stiff, and stool is normal after 7 days, and daily defecation is once.
In addition, the invention is not restricted to above-mentioned embodiment, as long as in without departing from the scope of the present invention, can take various Mode implements the present invention.

Claims (8)

1. a kind of Semen Tritici aestivi fiber crude granule, it is characterised in that including the following component counted in parts by weight:Semen Tritici aestivi fiber element 120- 240 parts, ethanol 30-58 parts, probiotics complexing agent 12-24 parts, hydrophilic macromolecular compounds 45-56 parts, maltodextrin 1-8 Part, chitosan 1-3 parts, ground rice 5-8 parts, rilanit special 2-5 parts, levulan 12-28 parts, deionized water 30-50 parts.
2. a kind of Semen Tritici aestivi fiber crude granule according to claim 1, it is characterised in that counted in parts by weight including following Component:220 parts of Semen Tritici aestivi fiber element, 48 parts of ethanol, 35 parts of probiotics complexing agent, 50 parts of hydrophilic macromolecular compounds, malt paste 5 parts of essence, 1 part of chitosan, 7 parts of ground rice, 3 parts of rilanit special, 25 parts of levulan, 40 parts of deionized water.
3. a kind of Semen Tritici aestivi fiber crude granule according to claim 1, it is characterised in that the probiotics compounding machine is by bifid Bacillus, Raman lactobacillus and lactobacillus acidophilus are 1 according to weight ratio:2-4:2.
A kind of 4. Semen Tritici aestivi fiber crude granule according to claim 1, it is characterised in that the hydrophilic macromolecular compounds Formed by the condensation of polyurethane, oxirane and dextrin.
5. a kind of Semen Tritici aestivi fiber crude granule according to claim 1, it is characterised in that the molecular weight of the chitosan is 1500-2000D。
6. the preparation method based on a kind of Semen Tritici aestivi fiber crude granule described in claim 1, it is characterised in that including following step Suddenly:Step 1, each component is weighed;Step 2, Semen Tritici aestivi fiber element is dissolved in ethanol after being evaporated under reduced pressure 20-40min at 30-50 DEG C, Maltodextrin and levulan are added, after stirring, is spray-dried to obtain fine powder;Step 3, by fine powder, hydrophilic macromolecule chemical combination Thing, chitosan, ground rice, rilanit special and deionized water mixing, after high speed shear reacts 40-60min, are granulated, are dried to and contain Water is less than 1-2% dry particl, you can.
7. the preparation method of a kind of Semen Tritici aestivi fiber crude granule according to claim 6, it is characterised in that depressurized in step 1 The pressure of distillation is 0.8-1.58KPa.
A kind of 8. preparation method of Semen Tritici aestivi fiber crude granule according to claim 6, it is characterised in that step 3 high speed The speed of shearing is 10000-12000rpm.
CN201710929352.9A 2017-10-09 2017-10-09 A kind of Semen Tritici aestivi fiber crude granule and preparation method thereof Pending CN107549822A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110037293A (en) * 2019-04-02 2019-07-23 安徽雁飞粮油有限责任公司 A kind of wheat compound nutritional particle and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101317666A (en) * 2008-07-18 2008-12-10 罗文礼 High-efficiency composite food cellulose and preparation method thereof

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101317666A (en) * 2008-07-18 2008-12-10 罗文礼 High-efficiency composite food cellulose and preparation method thereof

Non-Patent Citations (1)

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Title
吴为群: "《营养防病圣典.吴博士谈疾病调理》", 30 June 2015, 中国医药科技出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110037293A (en) * 2019-04-02 2019-07-23 安徽雁飞粮油有限责任公司 A kind of wheat compound nutritional particle and preparation method thereof

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Application publication date: 20180109