CN101683477A - Composition for fat-reducing - Google Patents
Composition for fat-reducing Download PDFInfo
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- CN101683477A CN101683477A CN200810140294A CN200810140294A CN101683477A CN 101683477 A CN101683477 A CN 101683477A CN 200810140294 A CN200810140294 A CN 200810140294A CN 200810140294 A CN200810140294 A CN 200810140294A CN 101683477 A CN101683477 A CN 101683477A
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Abstract
The invention relates to a composition having function of fat-reducing. Particularly, the invention relates to a fat-reducing composition containing xanthan gum, oligosaccharide and trace elements. Inaddition, vitamin and meal fibers can also be added into the composition. The composition of the invention can be prepared into various easy carried and edible forms according to a certain proportion, such as chewable tablets, capsules, granules, suspension and beverage, etc. The composition of the invention has function of fat-reducing, which is especially suitable for obesity patients or overweight persons.
Description
Technical field
The present invention relates to a kind of Weight reducing compound, specifically the present invention relates to contain the Weight reducing compound of xanthan gum, oligosaccharide, trace element.More specifically, the present composition also contains vitamin, dietary fiber except that containing xanthan gum, oligosaccharide, trace element.Again specifically, the present composition can be made various functional foods dosage form, that have weight losing function storing, transport, carry and eat of being suitable for, for example chewable tablet, capsule, granule, oral liquid, suspensoid.Compositions of the present invention can provide satiety, reduces the intake of food rich in fat, can promote defecation, thereby by controlling body weight, reaches the purpose of fat-reducing.Also can guarantee the body nutritive equilibrium simultaneously by replenishing the essential base substance of body.
Background technology
In recent years, the sickness rate of obesity obviously increases, and whole world obesity patient has 1,200,000,000 at present at least, and China's incidence of obesity reaches 17%, part big and medium-sized cities even surpass 55%, and students in middle and primary schools are fat, and youngster's ratio surpasses 20%, and fat total number of persons surpasses 100,000,000.Because obesity can cause metabolism and endocrine regulation, and often with illness such as diabetes, atherosclerosis, hyperlipidemia, hypertension, thereby obesity has become a current comparatively general social medicine problem.Up to now, the method for more common prevention and treatment of obesity has four kinds of pharmacotherapy, dietetic therapy, exercise therapy and the behavior therapy.Medicine with fat-reducing is mainly appetite suppressant, quickens metabolic hormone and some drugs, diarrhoea agent etc., but certain side effect is arranged mostly, and take too much, can cause serial homoiostasis imbalances such as dehydration, it is unfavorable to take health for a long time.And Drug therapy the time, generally also need cooperate low caloric diet increasing fat-reducing effect, otherwise be easy to draw backlash.In fact, be not only pharmacotherapy, even the exercise therapy and the behavior therapy also need in conjunction with low-calorie diet.As seen, dietetic therapy is the most basic, safest method of weight-reducing.Therefore, screening has the food or the functional food of the pure natural of antiobesity action, becomes an important topic in the fat-reducing research process.
But also there is chaotic situation in present diet food, and quality is uneven.Some diet food have added the thyroxin that bans use of, and can increase metabolic rate, but have increased heart rate, harmful effect such as nervous; Some adds certain Chinese herbal medicine, eliminating toxin and beautifying the skin, and essence is " diuresis ", makes the very fast decline of body weight by " diminishing ", the surface sees that " fat-reducing " effect is fine, but causes electrolyte disturbance easily, influences the metabolism of sugar, even influences renal function; What also have contains Radix Et Rhizoma Rhei or Folium Sennae constituents, and times of defecation is increased, and reduces body fluids and loss of weight, stops using the back bounce-back rapidly, and upsets total balance of the body, produces anemia and gastroenteropathy, and consumer is produced significant impact.Press for the diet food that only contains natural component on the market.
Summary of the invention
The purpose of this invention is to provide the Weight reducing compound that a kind of effect is remarkable, safe and reliable, be difficult for bounce-back.
Solution of the present invention is to consider the common and hyperalimentation of the cause of disease of obesity, and heat is too high relevant.If but by going on a diet weight reduction, may cause malnutrition, go down for a long time to cause apositia and ketoacidosis.Therefore, from this angle, people wish to have a kind of energy by prolonging the emptying time of stomach, increase satiety, and can also provide body necessary various materials, keep the product of nutritive equilibrium, taking back appetite suitably reduces, reduce the absorption of fattiness and heat, thereby made weight loss, reached the purpose of safe and reliable fat-reducing.The inventor seeks in the process of such active substance in research just, has finished the present composition.
The present composition is made up of xanthan gum, oligosaccharide, trace element.In addition, in order to improve effect of the present invention, the present composition also can add vitamin, dietary fiber.
The present composition is made up of following materials of weight proportions:
Xanthan gum 30-90
Oligosaccharide 5-60
Trace element 0.5-10
The present composition can also add vitamin, is preferred compositions, and its weight proportion is:
Xanthan gum 30-90
Oligosaccharide 5-60
Trace element 0.5-10
Vitamin 0.1-3
The present composition can also add dietary fiber, is most preferred compositions, and its weight proportion is:
Xanthan gum 30-90
Oligosaccharide 5-60
Trace element 0.5-10
Vitamin 0.1-3
Dietary fiber 3-20
The above-mentioned compositions that is used to lose weight by common process, can be made various functional foods dosage form, that have weight losing function storing, transport, carry and eat of being suitable for, for example chewable tablet, capsule, granule, suspension, beverage etc.
An important feature of the present invention is the mechanism of action of the xanthan gum imbibition in the said composition.Xanthan gum is a kind of microbial polysaccharide, claims HUANGJIAO, HANSHENGJIAO again, is to be primary raw material with starch, and through microbial fermentation and a series of biochemical process, a kind of biopolymer that finally obtains is a kind of novel fermentation product of getting up of newly-developed in the world.The xanthan gum main component is glucose, mannose, glucuronic acid etc.It has outstanding high viscosity and water solublity, unique rheological properties, good temperature stability and PH stability, gratifying compatibility and safety, as thickening agent, emulsifying agent, suspending agent, stabilizing agent, be widely used in fields such as food, health food, daily-use chemical industry.The inventor finds through long term studies, because xanthan gum has the characteristic of good imbibition, at first be to take the back to meet the rising of water viscosity, volume increases, and has delayed the emptying of gastric content, satiety is provided, reduce appetite, reduce the intake of food rich in fat, reduce the absorption of total amount of heat, thereby reach controlling body weight, the effect of fat-reducing.Because xanthan gum is a kind of microbial polysaccharide, be not absorbed by the body in small intestinal simultaneously, by suction, soften stool in intestinal, fat is also discharged thereupon, thereby reaches the purpose of loosening bowel to relieve constipation, fat-reducing.The inventor is by zoopery and human clinical's experiment on probation, and the result proves that all xanthan gum has the effect of fat-reducing.The inventor applies for a patent the research that (number of patent application is: 200810138185.7).
Another important feature of the present invention is the mechanism of action of the oligosaccharide propagation probiotics in the said composition.Oligosaccharide claims oligosaccharide again, mainly is present in the protease hydrolysate of human milk, Semen sojae atricolor, Semen Gossypii, Eucalyptus, Radix Betae, agueweed root and starch, studies confirm that oligosaccharide is difficult to therefore do not absorbed by ptyalin and the hydrolysis of small intestinal digestive enzyme in human body, not heat production is not converted into fat; The effect of its maximum simultaneously is to improve microecological environment in the human body, helps the propagation of bacillus bifidus and other probiotics, produces organic acid through metabolism the enteral pH value is reduced, and enterokinesia is accelerated, and changes the stool character, anti-treating constipation; Oligosaccharide can also pass through the bacillus bifidus of propagation, is that steroid excretes with the cholesterol oxidoreduction, disturbs and reduce the absorption again of cholic acid and cholesterol, the cholesterol in blood and the liver is reduced, thereby improved blood lipid metabolism.Above-mentioned functions can both play the effect of Weight-reducing and lipid-lowering.Oligosaccharide can also increase the synthetic and trace elements absorbed of vitamin simultaneously, improves immune function of human body.The oligosaccharide that the present invention adopts comprises the employed oligosaccharide of various food additive at least a of oligofructose, oligomeric lactose, oligomeric galactose, oligomeric isomaltose, oligomeric xylose or soybean oligo saccharide etc.
Another important feature of the present invention is that the trace element in the said composition is that human body must obligato composition.Trace element can be said so " edible cosmetics ", to the acid-base value in the health blood (PH) with permeate and be pressed with certain maintenance effect, and can keep the metabolism of other bodily tissue organs and internal organs, and keeps quantitatively constant in the blood, guarantees health.Can also assist metabolism,, decompose the ferment of the chemical reaction effect of no refuse as decomposing the neccessary composition that food is made.Therefore the present invention adopts trace element as one of effective ingredient, has effectively avoided because of satiety, after appetite depression, dietary intake reduce relatively, and human body institute essential trace element unbalance.The trace element that the present invention adopts is folic acid, calcium, phosphorus, magnesium, potassium, selenium, ferrum, copper, zinc, chromium and iodine.
Another important feature of the present invention is can also add certain vitamin in the said composition.Vitamin should be that human body can not synthesize (or synthetic quantity can not be satisfied the demand) and in human homergy's process with regulate the indispensable class material of physiological function.They are must be by the nutrient of food supply.Although requirement is few, only calculate with milligram or microgram every day, all must be by food supply, otherwise deficiency disease will appear, certain typical clinical symptoms appears.Therefore the present invention adds vitamin, has effectively avoided because of satiety, and after appetite depression, dietary intake reduced relatively, what human body institute must nutritional labeling was unbalance.The vitamin that the present invention adopts is vitamin A, vitamin C, vitamin D, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin K1 and vitamin B12.
Said vitamin and trace element are keeps body homergy and healthy requisite important substance.The two is the important component that constitutes multiple coenzyme and hormone, participates in saccharide, aminoacid, lipid metabolism in the body.Can cause dysbolismus during shortage, and cause multiple disease.
Other important feature of the present invention are can also add certain dietary fiber in the said composition.Dietary fiber be a kind of can not be by the carbohydrate of human consumption, be divided into water-insoluble and water-soluble fibre two big classes.Cellulose, hemicellulose and lignin are 3 kinds of common non-soluble fibers, are present in the plant cell wall; And pectin and natural gum etc. belong to water-soluble fibre, then are present in the natural non-fiber material.Dietary fiber has very important effect to promoting good digestion and draining solid waste.The supplementary fibre element can make the food in the intestinal increase deliquescing in right amount, promotes intestinal peristalsis promoting, thereby has accelerated defecation speed, prevents the risk of constipation and reduction intestinal cancer.In addition, cellulose can also reduce the absorption of digestion process to fat, thereby reduces the level of cholesterol, triglyceride in the blood, prevents and treats the effect of hypertension, cardiovascular and cerebrovascular disease.At least a in the group that the dietary fiber that the present invention adopts is formed for the dietary fiber of extraction from natural food (Rhizoma amorphophalli, Herba bromi japonici, Semen Fagopyri Esculenti, Fructus Mali pumilae, Radix Dauci Sativae, Sargassum, Thallus Laminariae (Thallus Eckloniae), Semen sojae atricolor).
Final purpose of the present invention has provided the present composition and has been convenient to the form of storing, carrying and eating, for example chewable tablet, capsule, granule, suspension, beverage etc.Its preparation can be carried out according to the conventional method of this area, according to those skilled in the art's general knowledge, adds field of food additive commonly used, for example carrier, diluent, disintegrating agent, correctives etc.
For reaching the fat-reducing purpose, the use amount of the present composition is per day for adults 0.8-20g normally, and preferred amount ranges is about 1.0-15g, and most preferred consumption is 2-10g, divides every day and takes for 1-2 time.Time of Administration is preferably with 1 hour before the meal, and is the most desirable before the dinner.
The invention provides a kind of safe and reliable Weight reducing compound without any side effects, its beneficial effect is:
1, present composition prescription is reasonable, and mechanism is clear and definite: xanthan gum produces satiety by making the people, has reduced total intake of food, has reduced the absorption of total amount of heat; Oligomeric xylose produces organic acid by the propagation probiotics, stimulates enterokinesia and defecation is discharged toxin simultaneously, blood fat reducing, blood sugar lowering; The interpolation of trace element has effectively been avoided because of after the satiety dietary intake relatively reduces, and what human body institute must nutritional labeling is unbalance.The three is collaborative, reaches the purpose of " fat-reducing is not harmful to the health ".On this prescription basis, preferably add vitamin again, avoided the unbalance of useful nutrition more; Preferably add dietary fiber again, the collaborative more intestinal peristalsis promoting that promoted is accelerated defecation speed, effectively prevents and treat constipation, is beneficial to fat-reducing more.
2, the composition of the present composition all obtains from natural food, and is safe and reliable.Except that vitamin, trace element, all the other all are not absorbed by the body, and energy value is almost nil, do not influence blood sugar concentration, and it is edible to be fit to each age group, are fit to diabetics yet and use.
3, in fat-reducing, all right blood fat reducing, blood sugar lowering.
The explanation of above-mentioned beneficial effect can see appended legend for details.
The specific embodiment
In order further to set forth content involved in the present invention, provided following embodiment.But the scope that these embodiment do not limit the present invention in any way.
The preparation of embodiment 1 present composition
Use the following feedstock production present composition
Xanthan gum 110g
Oligomeric xylose 80g
Folic acid 3.75mg
Calcium 2.5g
Phosphorus 1.25g
Potassium 1.5g
Magnesium 2.5g
Ferrum 1.8g
Copper 0.2g
Zinc 15mg
Iodine 15mg
Chromium 2.5mg
Selenium 2.5mg
Under the condition of control sterilization,, obtain the present composition with above-mentioned raw materials composition mix homogeneously.
The preparation of embodiment 2 present compositions
According to the method identical with embodiment 1, just according to following prescription, the preparation present composition:
Xanthan gum 100g
Oligofructose 90g
Vitamin A 5mg
Vitamin D 0.125mg
Vitamin E 325mg
Vitamin B1 25mg
Vitamin B2 25mg
Vitamin B6 25mg
Vitamin C 2.5g
Vitamin B12 0.6mg
Vitamin K1 2.5mg
Folic acid 3.75mg
Calcium 2.5g
Phosphorus 1.25g
Potassium 1.5g
Magnesium 2.5g
Ferrum 1.8g
Copper 0.2g
Zinc 15mg
Iodine 15mg
Chromium 2.5mg
Selenium 2.5mg
The preparation of embodiment 3 present compositions
According to the method identical with embodiment 1, just according to following prescription, the preparation present composition:
Xanthan gum 80g
Oligomeric xylose 70g
Dietary fiber (Sargassum) 40g
Vitamin A 5mg
Vitamin D 0.125mg
Vitamin E 325mg
Vitamin B1 25mg
Vitamin B2 25mg
Vitamin B6 25mg
Vitamin C 2.5g
Vitamin B12 0.6mg
Vitamin K1 2.5mg
Folic acid 3.75mg
Calcium 2.5g
Phosphorus 1.25g
Potassium 1.5g
Magnesium 2.5g
Ferrum 1.8g
Copper 0.2g
Zinc 15mg
Iodine 15mg
Chromium 2.5mg
Selenium 2.5mg
The preparation of embodiment 4 present composition chewable tablet
It is dry that the compositions of embodiment 1 gained is granulated, and adds field of food additive commonly used, and for example citric acid, aspartame, milk flavour etc. are made sheet with tablet machine and heavily be the tablet of 2.5g, be total to 100, be chewable tablet of the present invention.
The preparation of embodiment 5 present composition capsules
It is dry that the compositions of embodiment 2 gained is granulated, and adds formulation art additive commonly used, for example microcrystalline Cellulose, magnesium stearate etc., mixing is dressed up the capsule of 0.5g/ grain with capsule filling machine, altogether 500, be capsule of the present invention.
The preparation of embodiment 6 present composition suspensions
With the compositions of embodiment 3 gained, add formulation art additive commonly used, 0.3% sodium benzoate for example, 20% sucrose, heating makes dissolving, shake up, 1000ml, be suspension of the present invention.Legend of the present invention is seen Figure of description, and Figure of description forms and be used in the figure of the effect in the weight losing function food for Weight reducing compound of the present invention.
Claims (12)
1, a kind of Weight reducing compound, said composition contains xanthan gum, oligosaccharide and trace element.Said composition can provide satiety, reduces the intake of food rich in fat, promotes defecation, by controlling body weight, reaches the purpose of fat-reducing.Replenish useful nutrient simultaneously, keep normal human nutrition balance.
2, according to the described compositions that is used to lose weight of claim 1, except that containing xanthan gum, oligosaccharide and trace element, also contain vitamin, dietary fiber.
3, according to the described compositions that is used to lose weight of claim 1, wherein said oligosaccharide is at least a in the group formed of oligofructose, oligomeric lactose, oligomeric galactose, oligomeric isomaltose, oligomeric xylose or soybean oligo saccharide.
4, according to the described compositions that is used to lose weight of claim 1, wherein said trace element is folic acid, calcium, phosphorus, magnesium, potassium, selenium, ferrum, copper, zinc, chromium and iodine.
5, according to the described compositions that is used to lose weight of claim 2, wherein said vitamin is vitamin A, vitamin C, vitamin D, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin K1 and vitamin B12.
6, according to the described compositions that is used to lose weight of claim 2, at least a in the group that wherein said dietary fiber is formed for the dietary fiber that extracts from natural food.
Above-mentioned natural food is from Rhizoma amorphophalli, Herba bromi japonici, Semen Fagopyri Esculenti, Fructus Mali pumilae, Radix Dauci Sativae, Sargassum, Thallus Laminariae (Thallus Eckloniae) or Semen sojae atricolor.
7, according to the described compositions that is used to lose weight of claim 1, the content of described xanthan gum is 30～90% of total composition.
8, according to the described compositions that is used to lose weight of claim 1, the content of described oligosaccharide is 5～60% of total composition.
9, according to the described compositions that is used to lose weight of claim 1, described content of elements is 0.5～10% of a total composition.
10, according to the described compositions that is used to lose weight of claim 2, the content of described vitamin is 0.1～3% of total composition.
11, according to the described compositions that is used to lose weight of claim 2, the content of described dietary fiber is 3～20% of total composition.
12, according to claim 1 and the described compositions that is used to lose weight of claim 2, described compositions can be made into the form of chewable tablet, capsule, granule, suspension, beverage.
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| CN200810140294A CN101683477A (en) | 2008-09-25 | 2008-09-25 | Composition for fat-reducing |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102524640A (en) * | 2011-12-27 | 2012-07-04 | 赫康贸易(上海)有限公司 | Gut purging powder capable of shaping intestine-like model |
| CN103478738A (en) * | 2013-09-17 | 2014-01-01 | 深圳太太药业有限公司 | Composite with weight-reducing, body-shaping and weight-controlling functions |
| CN103834068A (en) * | 2014-03-23 | 2014-06-04 | 许自霖 | Compound natural polysaccharide with effect of reducing blood fat |
| CN105400896A (en) * | 2015-12-26 | 2016-03-16 | 上海中优生物高科技有限责任公司 | Preparation method and system of nervous centralis type obese gene individualization intervention composition |
| CN105400897A (en) * | 2015-12-26 | 2016-03-16 | 上海中优生物高科技有限责任公司 | Preparation method and system of energy imbalance type obese gene individualization intervention composition |
| CN105483234A (en) * | 2015-12-26 | 2016-04-13 | 上海中优生物高科技有限责任公司 | Hypertension-type obese gene individualization intervention composition and preparation method and system |
| CN105506080A (en) * | 2015-12-26 | 2016-04-20 | 上海中优生物高科技有限责任公司 | Individual intervention composition for lipid metabolism type obese gene as well as preparation method and system |
| CN105707887A (en) * | 2016-03-03 | 2016-06-29 | 山东禹王制药有限公司 | Health care and weight loss chewable tablet and preparation method thereof |
| CN108201143A (en) * | 2016-12-19 | 2018-06-26 | 中国石油天然气股份有限公司 | The weary nutrient matrix of fat reducing, the food comprising it and application |
| CN110496135A (en) * | 2019-09-27 | 2019-11-26 | 南京易亨制药有限公司 | A kind of composition for weight-reducing |
| CN112690457A (en) * | 2020-12-24 | 2021-04-23 | 石药集团中诺药业（泰州）有限公司 | Nutrient composition formula for overweight and obese people |
-
2008
- 2008-09-25 CN CN200810140294A patent/CN101683477A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102524640A (en) * | 2011-12-27 | 2012-07-04 | 赫康贸易(上海)有限公司 | Gut purging powder capable of shaping intestine-like model |
| CN103478738A (en) * | 2013-09-17 | 2014-01-01 | 深圳太太药业有限公司 | Composite with weight-reducing, body-shaping and weight-controlling functions |
| CN103478738B (en) * | 2013-09-17 | 2016-02-10 | 深圳太太药业有限公司 | A kind of composition with fat-reducing body shaping and Weight management effect |
| CN103834068A (en) * | 2014-03-23 | 2014-06-04 | 许自霖 | Compound natural polysaccharide with effect of reducing blood fat |
| CN105483234A (en) * | 2015-12-26 | 2016-04-13 | 上海中优生物高科技有限责任公司 | Hypertension-type obese gene individualization intervention composition and preparation method and system |
| CN105400897A (en) * | 2015-12-26 | 2016-03-16 | 上海中优生物高科技有限责任公司 | Preparation method and system of energy imbalance type obese gene individualization intervention composition |
| CN105400896A (en) * | 2015-12-26 | 2016-03-16 | 上海中优生物高科技有限责任公司 | Preparation method and system of nervous centralis type obese gene individualization intervention composition |
| CN105506080A (en) * | 2015-12-26 | 2016-04-20 | 上海中优生物高科技有限责任公司 | Individual intervention composition for lipid metabolism type obese gene as well as preparation method and system |
| CN105707887A (en) * | 2016-03-03 | 2016-06-29 | 山东禹王制药有限公司 | Health care and weight loss chewable tablet and preparation method thereof |
| CN108201143A (en) * | 2016-12-19 | 2018-06-26 | 中国石油天然气股份有限公司 | The weary nutrient matrix of fat reducing, the food comprising it and application |
| CN110496135A (en) * | 2019-09-27 | 2019-11-26 | 南京易亨制药有限公司 | A kind of composition for weight-reducing |
| CN110496135B (en) * | 2019-09-27 | 2022-02-01 | 南京易亨制药有限公司 | Composition for losing weight |
| CN112690457A (en) * | 2020-12-24 | 2021-04-23 | 石药集团中诺药业（泰州）有限公司 | Nutrient composition formula for overweight and obese people |
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Open date: 20100331 |