CN112972350A - Alcohol-free surgical hand disinfectant - Google Patents

Alcohol-free surgical hand disinfectant Download PDF

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Publication number
CN112972350A
CN112972350A CN202011518268.6A CN202011518268A CN112972350A CN 112972350 A CN112972350 A CN 112972350A CN 202011518268 A CN202011518268 A CN 202011518268A CN 112972350 A CN112972350 A CN 112972350A
Authority
CN
China
Prior art keywords
alcohol
uniformly stirring
surgical hand
stirring
pure water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011518268.6A
Other languages
Chinese (zh)
Inventor
郭晓墘
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xipu Fujian Medical Products Co ltd
Original Assignee
Xipu Fujian Medical Products Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xipu Fujian Medical Products Co ltd filed Critical Xipu Fujian Medical Products Co ltd
Priority to CN202011518268.6A priority Critical patent/CN112972350A/en
Publication of CN112972350A publication Critical patent/CN112972350A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

Abstract

The invention discloses an alcohol-free surgical hand disinfectant, which comprises polyhexamethylene biguanide hydrochloride, chlorhexidine acetate, a natural organic antibacterial deodorant, an aloe extract, glycerin, peppermint oil and pure water. The invention belongs to the technical field of disinfectants, and particularly relates to an alcohol-free surgical hand disinfectant.

Description

Alcohol-free surgical hand disinfectant
Technical Field
The invention belongs to the technical field of disinfectants, and particularly relates to an alcohol-free surgical hand disinfectant.
Background
Healthcare professionals have a significantly higher risk of hand eczema, dermatitis, and other skin problems than the general population. These conditions not only cause problems for medical care work, but also affect patient populations. For example, eczema can contribute to the spread of nosocomial infections. More than 90% of people with moderate to severe eczema are infected with staphylococcus aureus. Staphylococcal infection can be fatal. In particular, strains with antibiotic resistance are difficult to control. Thus, the prevalence of eczema among healthcare employees is a serious problem.
For people with eczema, washing the hands with soap and water can cause further irritation and impede healing. This is why many healthcare workers instead rely on hand sanitizers as an alternative or supplement to hand washing. It is estimated that 40% of all hospital-caused infections result from inadequate hand disinfection, the main cause of which is skin allergy. Hand sanitizers or hand sanitizers are typically gels, foams, or liquid solutions containing active ingredients for killing microorganisms. Most hand sanitizers include alcohols in the form of ethanol or isopropanol.
Alcohol-based hand disinfectants can actually exacerbate the problem for people with eczema by promoting the autoimmune response that causes eczema. When exposed to alcohol, viable staphylococcus aureus and other bacteria respond by producing a protective biofilm. Biofilms are known to impair skin wound healing and reduce local antimicrobial efficiency, and are capable of transmitting bacteria into the air. At the same time, bacteria with antibiotic resistance, such as MRSA, can proliferate in biofilms, resulting in many serious and fatal nosocomial infections. Eczema, particularly of healthcare providers, remains a major concern for public health.
Disclosure of Invention
Aiming at the situation and overcoming the defects of the prior art, the invention provides the non-alcoholic surgical hand disinfectant, which adopts the biguanide component which is mild and non-irritating, and has the functions of sterilization and disinfection, deodorization and deodorization of the natural organic antibacterial deodorant, namely the grain amino acid component, skin care and skin moistening of aloe and glycerin, and cooling and refreshing mint.
The technical scheme adopted by the invention is as follows: the invention relates to a nonalcoholic surgical hand disinfectant, which comprises polyhexamethylene biguanide hydrochloride, chlorhexidine acetate, a natural organic antibacterial deodorant, an aloe extract, glycerin, peppermint oil, pure water and essence.
A preparation process of an alcohol-free surgical hand disinfectant comprises the following steps:
1) taking 50.5g of chlorhexidine acetate, adding 45kg of pure water, stirring and dissolving;
2) adding 500g of 20% polyhexamethylene biguanide, and uniformly stirring;
3) adding 50g of natural organic antibacterial deodorant, and uniformly stirring;
4) adding 100g of water-soluble peppermint oil, and uniformly stirring;
5) adding 50g of aloe extract, and uniformly stirring;
6) adding 500g of glycerol, and uniformly stirring;
7) adding 50g of essence, and uniformly stirring and mixing;
8) adding pure water to 50kg, and stirring and mixing uniformly;
9) preparing 21 barrels;
10) packaging 300 ml 3500 bottles;
11) and (5) checking and putting the product into a finished product warehouse after the product is qualified.
The invention with the structure has the following beneficial effects: the alcohol-free surgical hand disinfectant adopts the biguanide components which are mild and non-irritating, and has the effects of sterilization and disinfection, deodorization and deodorization of natural organic antibacterial deodorant cereal amino acid components, skin care and skin moistening by aloe and glycerol, and cooling and refreshing mint.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention relates to a nonalcoholic surgical hand disinfectant, which comprises polyhexamethylene biguanide hydrochloride, chlorhexidine acetate, a natural organic antibacterial deodorant, an aloe extract, glycerin, peppermint oil and pure water.
A preparation process of an alcohol-free surgical hand disinfectant comprises the following steps:
1) taking 50.5g of chlorhexidine acetate, adding 45kg of pure water, stirring and dissolving;
2) adding 500g of 20% polyhexamethylene biguanide, and uniformly stirring;
3) adding 50g of natural organic antibacterial deodorant, and uniformly stirring;
4) adding 100g of water-soluble peppermint oil, and uniformly stirring;
5) adding 50g of aloe extract, and uniformly stirring;
6) adding 500g of glycerol, and uniformly stirring;
7) adding 50g of essence, and uniformly stirring and mixing;
8) adding pure water to 50kg, and stirring and mixing uniformly;
9) preparing 21 barrels;
10) packaging 300 ml 3500 bottles;
11) and (5) checking and putting the product into a finished product warehouse after the product is qualified.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
The present invention and the embodiments thereof have been described above, and the description is not restrictive, but is only one of the embodiments of the present invention, and is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (2)

1. An alcohol-free surgical hand sanitizer, comprising: comprises polyhexamethylene biguanide hydrochloride, chlorhexidine acetate, natural organic antibacterial deodorant, aloe extract, glycerin, peppermint oil and pure water.
2. A preparation process of an alcohol-free surgical hand disinfectant is characterized by comprising the following steps:
1) taking 50.5g of chlorhexidine acetate, adding 45kg of pure water, stirring and dissolving;
2) adding 500g of 20% polyhexamethylene biguanide, and uniformly stirring;
3) adding 50g of natural organic antibacterial deodorant, and uniformly stirring;
4) adding 100g of water-soluble peppermint oil, and uniformly stirring;
5) adding 50g of aloe extract, and uniformly stirring;
6) adding 500g of glycerol, and uniformly stirring;
7) adding 50g of essence, and uniformly stirring and mixing;
8) adding pure water to 50kg, and stirring and mixing uniformly;
9) preparing 21 barrels;
10) packaging 300 ml 3500 bottles;
11) and (5) checking and putting the product into a finished product warehouse after the product is qualified.
CN202011518268.6A 2020-12-21 2020-12-21 Alcohol-free surgical hand disinfectant Pending CN112972350A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011518268.6A CN112972350A (en) 2020-12-21 2020-12-21 Alcohol-free surgical hand disinfectant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011518268.6A CN112972350A (en) 2020-12-21 2020-12-21 Alcohol-free surgical hand disinfectant

Publications (1)

Publication Number Publication Date
CN112972350A true CN112972350A (en) 2021-06-18

Family

ID=76345046

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011518268.6A Pending CN112972350A (en) 2020-12-21 2020-12-21 Alcohol-free surgical hand disinfectant

Country Status (1)

Country Link
CN (1) CN112972350A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101300976A (en) * 2007-05-11 2008-11-12 增井吉晴 Antibacterial deodorizer
CN105362212A (en) * 2015-12-18 2016-03-02 南京巨鲨显示科技有限公司 Washing-free sterilizing gel and preparing method thereof
CN111184658A (en) * 2020-03-06 2020-05-22 吉林云飞医药有限公司 Hand disinfectant and preparation method thereof
CN111494280A (en) * 2020-05-11 2020-08-07 南京绿界新材料研究院有限公司 Sterilizing and disinfecting composition
CN111544337A (en) * 2020-06-17 2020-08-18 广东中科天元新能源科技有限公司 Hyaluronic acid-containing moisturizing and skin-moistening no-wash gel disinfectant and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101300976A (en) * 2007-05-11 2008-11-12 增井吉晴 Antibacterial deodorizer
CN105362212A (en) * 2015-12-18 2016-03-02 南京巨鲨显示科技有限公司 Washing-free sterilizing gel and preparing method thereof
CN111184658A (en) * 2020-03-06 2020-05-22 吉林云飞医药有限公司 Hand disinfectant and preparation method thereof
CN111494280A (en) * 2020-05-11 2020-08-07 南京绿界新材料研究院有限公司 Sterilizing and disinfecting composition
CN111544337A (en) * 2020-06-17 2020-08-18 广东中科天元新能源科技有限公司 Hyaluronic acid-containing moisturizing and skin-moistening no-wash gel disinfectant and preparation method thereof

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Application publication date: 20210618