CN112168729A - Rosemary disinfection hand sanitizer and preparation method thereof - Google Patents
Rosemary disinfection hand sanitizer and preparation method thereof Download PDFInfo
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- CN112168729A CN112168729A CN202011087480.1A CN202011087480A CN112168729A CN 112168729 A CN112168729 A CN 112168729A CN 202011087480 A CN202011087480 A CN 202011087480A CN 112168729 A CN112168729 A CN 112168729A
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- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 244000178231 Rosmarinus officinalis Species 0.000 title claims description 37
- 239000000645 desinfectant Substances 0.000 claims abstract description 36
- 239000003906 humectant Substances 0.000 claims abstract description 25
- 239000004094 surface-active agent Substances 0.000 claims abstract description 25
- 239000002562 thickening agent Substances 0.000 claims abstract description 25
- 239000008213 purified water Substances 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 229960000686 benzalkonium chloride Drugs 0.000 claims abstract description 14
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229940092258 rosemary extract Drugs 0.000 claims abstract description 14
- 235000020748 rosemary extract Nutrition 0.000 claims abstract description 14
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- 239000011259 mixed solution Substances 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 18
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 239000000243 solution Substances 0.000 claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 239000003205 fragrance Substances 0.000 claims description 6
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 claims description 5
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 claims description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 4
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims description 4
- 235000011130 ammonium sulphate Nutrition 0.000 claims description 4
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 4
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 235000005979 Citrus limon Nutrition 0.000 claims description 3
- 244000131522 Citrus pyriformis Species 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- 235000010254 Jasminum officinale Nutrition 0.000 claims description 3
- 240000005385 Jasminum sambac Species 0.000 claims description 3
- 244000178870 Lavandula angustifolia Species 0.000 claims description 3
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims description 3
- 241000220317 Rosa Species 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims description 3
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims description 3
- 239000001102 lavandula vera Substances 0.000 claims description 3
- 235000018219 lavender Nutrition 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 2
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- 239000008868 Flower Essence Substances 0.000 claims description 2
- 244000111489 Gardenia augusta Species 0.000 claims description 2
- XINCECQTMHSORG-UHFFFAOYSA-N Isoamyl isovalerate Chemical compound CC(C)CCOC(=O)CC(C)C XINCECQTMHSORG-UHFFFAOYSA-N 0.000 claims description 2
- 244000242564 Osmanthus fragrans Species 0.000 claims description 2
- 235000019083 Osmanthus fragrans Nutrition 0.000 claims description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 2
- 240000006365 Vitis vinifera Species 0.000 claims description 2
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims description 2
- 239000008369 fruit flavor Substances 0.000 claims description 2
- 235000014104 aloe vera supplement Nutrition 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 235000013772 propylene glycol Nutrition 0.000 claims 1
- 235000010356 sorbitol Nutrition 0.000 claims 1
- DOUMFZQKYFQNTF-WUTVXBCWSA-N (R)-rosmarinic acid Chemical compound C([C@H](C(=O)O)OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-WUTVXBCWSA-N 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 238000005406 washing Methods 0.000 abstract description 6
- 206010061218 Inflammation Diseases 0.000 abstract description 5
- 230000004054 inflammatory process Effects 0.000 abstract description 5
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 4
- ZZAFFYPNLYCDEP-HNNXBMFYSA-N Rosmarinsaeure Natural products OC(=O)[C@H](Cc1cccc(O)c1O)OC(=O)C=Cc2ccc(O)c(O)c2 ZZAFFYPNLYCDEP-HNNXBMFYSA-N 0.000 abstract description 3
- 230000003647 oxidation Effects 0.000 abstract description 3
- 238000007254 oxidation reaction Methods 0.000 abstract description 3
- DOUMFZQKYFQNTF-MRXNPFEDSA-N rosemarinic acid Natural products C([C@H](C(=O)O)OC(=O)C=CC=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-MRXNPFEDSA-N 0.000 abstract description 3
- TVHVQJFBWRLYOD-UHFFFAOYSA-N rosmarinic acid Natural products OC(=O)C(Cc1ccc(O)c(O)c1)OC(=Cc2ccc(O)c(O)c2)C=O TVHVQJFBWRLYOD-UHFFFAOYSA-N 0.000 abstract description 3
- 206010040880 Skin irritation Diseases 0.000 abstract description 2
- 230000007797 corrosion Effects 0.000 abstract description 2
- 238000005260 corrosion Methods 0.000 abstract description 2
- 239000003755 preservative agent Substances 0.000 abstract description 2
- 230000002335 preservative effect Effects 0.000 abstract description 2
- 230000036556 skin irritation Effects 0.000 abstract description 2
- 231100000475 skin irritation Toxicity 0.000 abstract description 2
- 241001529742 Rosmarinus Species 0.000 abstract 3
- 239000000686 essence Substances 0.000 description 42
- 230000003020 moisturizing effect Effects 0.000 description 8
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 229940069521 aloe extract Drugs 0.000 description 3
- 230000003385 bacteriostatic effect Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- -1 alkenyl sulfonate Chemical compound 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- QRYRORQUOLYVBU-VBKZILBWSA-N carnosic acid Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 description 2
- 125000000373 fatty alcohol group Chemical group 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229940096998 ursolic acid Drugs 0.000 description 1
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Abstract
The invention belongs to the technical field of washing and protecting articles, and particularly relates to rosemary disinfection hand sanitizer which is prepared from the following raw materials in parts by weight: 30-50 parts of disinfectant, 3-8 parts of surfactant, 1-2 parts of humectant, 0.5-1 part of thickening agent, 0.5-1.5 parts of pH regulator, 0.05-1 part of essence and 20-40 parts of purified water, and the invention also discloses a preparation method of the rosemary disinfection hand sanitizer; in the rosemary disinfection hand sanitizer, the disinfectant is a mixture of benzalkonium chloride and a rosemary extract, the benzalkonium chloride has broad-spectrum and efficient bactericidal capability, rosmarinic acid serving as a main component of the rosemary extract has the effects of bacteriostasis, disinfection, oxidation resistance, corrosion resistance and inflammation resistance, no preservative is required to be added, and inflammation such as skin irritation and the like cannot be caused.
Description
Technical Field
The invention belongs to the technical field of washing and caring articles, and particularly relates to a rosemary disinfection hand sanitizer and a preparation method thereof.
Background
In daily life and work of people, both hands are infected with various bacteria due to frequent contact with external objects, and the hands can be thoroughly cleaned by selecting a hand sanitizer with sterilization and disinfection effects; therefore, how to overcome the above technical problems and disadvantages is a problem to be solved.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides the rosemary disinfection hand sanitizer and the preparation method thereof.
The purpose of the invention is realized as follows:
rosemary disinfection hand sanitizer is prepared from the following raw materials in parts by weight: 30-50 parts of disinfectant, 3-8 parts of surfactant, 1-2 parts of humectant, 0.5-1 part of thickening agent, 0.5-1.5 parts of pH regulator, 0.05-1 part of essence and 20-40 parts of purified water.
Furthermore, the rosemary disinfection hand sanitizer is prepared from the following raw materials in parts by weight: 35-45 parts of disinfectant, 4-6 parts of surfactant, 1.3-1.7 parts of humectant, 0.7-0.9 part of thickening agent, 0.8-1.2 parts of pH regulator, 0.2-0.8 part of essence and 25-35 parts of purified water.
Furthermore, the rosemary disinfection hand sanitizer is prepared from the following raw materials in parts by weight: 40 parts of disinfectant, 5 parts of surfactant, 1.5 parts of humectant, 0.7 part of thickening agent, 1 part of pH regulator, 0.5 part of essence and 30 parts of purified water.
Further, the disinfectant is a mixture of benzalkonium chloride and rosemary extract, wherein the weight ratio of benzalkonium chloride to rosemary extract is 0.1-0.5: 1.
Further, the surfactant is one or more of fatty alcohol polyoxyethylene ether ammonium sulfate, alpha-sodium alkenyl sulfonate and sodium dodecyl benzene sulfonate.
Further, the humectant is one or more of aloe extract, glycerin, sorbitol, and propylene glycol.
Further, the thickening agent is one or more of hydroxymethyl cellulose, sodium chloride, polyvinylpyrrolidone and polyvinyl alcohol.
Further, the pH regulator is citric acid.
Further, the essence is a flower-fragrance type essence or a fruit-fragrance type essence;
wherein the flower essence is one or more of rose essence, jasmine essence, gardenia essence, lavender essence, sweet osmanthus essence, violet essence and chrysanthemum essence;
the fruit-flavor essence is one or more of apple essence, orange essence, grape essence and lemon essence.
Further, the preparation method of the rosemary disinfection hand sanitizer comprises the following steps:
(1) weighing various raw materials according to the proportion of the rosemary disinfection hand sanitizer;
(2) adding the thickener with the formula amount into the purified water with the formula amount, and stirring for 10-20 minutes to obtain a mixed solution A;
(3) adding the disinfectant with the formula amount into the mixed solution A, stirring for 10-20 minutes, then adding the humectant with the formula amount, continuously stirring for 5-10 minutes, adding the surfactant with the formula amount, and continuously stirring for 20-30 minutes to obtain a mixed solution B;
(4) adding the essence with the formula amount into the mixed solution B, and stirring for 10-20 minutes to obtain a mixed solution C;
(5) and adding the pH regulator into the mixed solution C according to the formula amount, regulating the pH of the solution to 6-7, stirring for 1-2 hours, and bottling to obtain the rosemary disinfection hand sanitizer.
The rosemary disinfection hand sanitizer has the beneficial effects that:
1. the rosemary disinfection hand sanitizer is prepared from a disinfectant, a surfactant, a humectant, a thickening agent, a pH regulator, essence and purified water, is rich in foam, is easy to flush, can effectively inhibit staphylococcus aureus and escherichia coli, is long in antibacterial disinfection duration, free of irritation and damage to skin, good in moisturizing effect, and has the effects of delaying skin aging, resisting bacteria, inflammation, oxidation and moisturizing.
2. In the rosemary disinfection hand sanitizer, the disinfectant is a mixture of benzalkonium chloride and a rosemary extract, the benzalkonium chloride is a non-oxidative bactericide and has broad-spectrum and high-efficiency bactericidal capability, the main components of the rosemary extract comprise rosmarinic acid, carnosic acid and ursolic acid, and the rosmarinic acid has the effects of bacteriostasis, disinfection, oxidation resistance, corrosion resistance and inflammation resistance, can effectively inhibit staphylococcus aureus and escherichia coli, is long in bacteriostasis and disinfection duration, does not need to be added with a preservative, and cannot cause inflammation such as skin irritation.
3. In the rosemary disinfection hand sanitizer, the essence is a flower-fragrance type essence or a fruit-fragrance type essence which are both natural essences, so that the rosemary disinfection hand sanitizer has no side effect and does not irritate the skin.
Detailed Description
The rosemary disinfectant hand sanitizer of the present invention is described in more detail by the following specific embodiments.
Example 1
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 32 parts of disinfectant, 4 parts of surfactant, 1.5 parts of humectant, 0.5 part of thickening agent, 0.8 part of pH regulator, 0.1 part of essence and 25 parts of purified water.
Wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is fatty alcohol polyoxyethylene ether ammonium sulfate, the humectant is aloe extract, the thickening agent is polyvinyl alcohol, the pH regulator is citric acid, and the essence is jasmine essence.
Example 2
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 35 parts of disinfectant, 3 parts of surfactant, 1.3 parts of humectant, 0.6 part of thickening agent, 0.6 part of pH regulator, 0.05 part of essence and 20 parts of purified water.
Wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is sodium dodecyl benzene sulfonate, the humectant is sorbitol, the thickener is hydroxymethyl cellulose, the pH regulator is citric acid, and the essence is orange essence.
Example 3
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 40 parts of disinfectant, 5 parts of surfactant, 1.5 parts of humectant, 0.7 part of thickening agent, 1 part of pH regulator, 0.5 part of essence and 30 parts of purified water.
Wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is sodium dodecyl benzene sulfonate, the humectant is aloe extract, the thickening agent is sodium chloride, the pH regulator is citric acid, and the essence is lavender essence.
Example 4
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 30 parts of disinfectant, 6 parts of surfactant, 1 part of humectant, 0.8 part of thickening agent, 0.5 part of pH regulator, 0.15 part of essence and 35 parts of purified water.
Wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is alpha-sodium alkenyl sulfonate, the humectant is glycerin, the thickening agent is polyvinylpyrrolidone, the pH regulator is citric acid, and the essence is violet essence.
Example 5
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 45 parts of disinfectant, 7 parts of surfactant, 1.7 parts of humectant, 0.9 part of thickening agent, 1.5 parts of pH regulator, 1 part of essence and 32 parts of purified water.
The disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is fatty alcohol polyoxyethylene ether ammonium sulfate, the humectant is propylene glycol, the thickening agent is sodium chloride, the pH regulator is citric acid, and the essence is lemon essence.
Example 6
The rosemary disinfection hand sanitizer disclosed by the invention is prepared from the following raw materials in parts by weight: 50 parts of disinfectant, 8 parts of surfactant, 2 parts of humectant, 1 part of thickener, 1.2 parts of pH regulator, 0.8 part of essence and 40 parts of purified water.
Wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract in a weight ratio of 0.1:1, the surfactant is sodium dodecyl benzene sulfonate, the humectant is propylene glycol, the thickening agent is polyvinyl alcohol, the pH regulator is citric acid, and the essence is rose essence.
The preparation method of the rosemary disinfection hand sanitizer disclosed in the embodiments 1-6 comprises the following steps:
(1) weighing various raw materials according to the proportion of the rosemary disinfection hand sanitizer;
(2) adding the thickener with the formula amount into the purified water with the formula amount, and stirring for 10-20 minutes to obtain a mixed solution A;
(3) adding the disinfectant with the formula amount into the mixed solution A, stirring for 10-20 minutes, then adding the humectant with the formula amount, continuously stirring for 5-10 minutes, adding the surfactant with the formula amount, and continuously stirring for 20-30 minutes to obtain a mixed solution B;
(4) adding the essence with the formula amount into the mixed solution B, and stirring for 10-20 minutes to obtain a mixed solution C;
(5) and adding the pH regulator into the mixed solution C according to the formula amount, regulating the pH of the solution to 6-7, stirring for 1-2 hours, and bottling to obtain the rosemary disinfection hand sanitizer.
Test example 1: test of sterilizing Effect
The hand sanitizer prepared in examples 1 to 6 is used as an experimental group, a common hand sanitizer sold in the market is used as a control group, 10 persons are selected as experimental objects in each group, the bacterial load on hands is measured before cleaning, the bacterial load on hands is measured at the same time interval after cleaning, the dosage of the hand sanitizer is the same, and the sterilization effect of the hand sanitizer is shown in table 1:
TABLE 1 germicidal Effect of the hand lotions
As can be seen from the data in Table 1, the hand sanitizer prepared by the embodiment 1-6 of the invention can effectively inhibit staphylococcus aureus and escherichia coli, has better bacteriostatic effect and duration than common hand sanitizers sold in the market, and has good bacteriostatic and disinfectant effects and long bacteriostatic and disinfectant duration.
Test example 2: test of moisturizing Effect
The hand washing solutions prepared in examples 1 to 6 were used as experimental groups, common hand washing solutions sold in the market were used as control groups, 10 persons were selected for each group as experimental subjects, the hand wetting conditions of the experimental subjects were observed at the same time interval after cleaning, the dosage of the hand washing solutions was the same, and the moisturizing effects of the hand washing solutions are shown in table 2:
TABLE 2 moisturizing effect of hand lotions
As can be seen from the data in Table 2, the hand sanitizer prepared by the embodiment 1-6 of the invention has better moisturizing effect and moisturizing durability than common hand sanitizers sold in the market, and has good moisturizing effect.
The foregoing is a more detailed description of the present invention that is presented in conjunction with specific embodiments, and the practice of the invention is not to be considered limited to those descriptions. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.
Claims (10)
1. The rosemary disinfection hand sanitizer is characterized by comprising the following raw materials in parts by weight: 30-50 parts of disinfectant, 3-8 parts of surfactant, 1-2 parts of humectant, 0.5-1 part of thickening agent, 0.5-1.5 parts of pH regulator, 0.05-1 part of essence and 20-40 parts of purified water.
2. The rosemary disinfection hand sanitizer according to claim 1, which is composed of the following raw materials in parts by weight: 35-45 parts of disinfectant, 4-6 parts of surfactant, 1.3-1.7 parts of humectant, 0.7-0.9 part of thickening agent, 0.8-1.2 parts of pH regulator, 0.2-0.8 part of essence and 25-35 parts of purified water.
3. The rosemary disinfection hand sanitizer according to claim 1, which is composed of the following raw materials in parts by weight: 40 parts of disinfectant, 5 parts of surfactant, 1.5 parts of humectant, 0.7 part of thickening agent, 1 part of pH regulator, 0.5 part of essence and 30 parts of purified water.
4. The rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the disinfectant is a mixture of benzalkonium chloride and rosemary extract, wherein the weight ratio of benzalkonium chloride to rosemary extract is 0.1-0.5: 1.
5. A rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the surfactant is one or more of fatty alcohol polyoxyethylene ether ammonium sulfate, sodium alpha-alkenyl sulfonate, sodium dodecyl benzene sulfonate.
6. A rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the humectant is one or more of aloe vera extract, glycerine, sorbitol, propylene glycol.
7. A rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the thickener is one or more of hydroxymethylcellulose, sodium chloride, polyvinylpyrrolidone, polyvinyl alcohol.
8. A rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the pH adjuster is citric acid.
9. A rosemary disinfectant hand sanitizer according to any one of claims 1 to 3, wherein the fragrance is a floral or fruity fragrance;
wherein the flower essence is one or more of rose essence, jasmine essence, gardenia essence, lavender essence, sweet osmanthus essence, violet essence and chrysanthemum essence;
the fruit-flavor essence is one or more of apple essence, orange essence, grape essence and lemon essence.
10. A preparation method of rosemary disinfection hand sanitizer is characterized by comprising the following steps:
(1) weighing the raw materials according to the proportion of the rosemary disinfection hand sanitizer according to any one of claims 1 to 3;
(2) adding the thickener with the formula amount into the purified water with the formula amount, and stirring for 10-20 minutes to obtain a mixed solution A;
(3) adding the disinfectant with the formula amount into the mixed solution A, stirring for 10-20 minutes, then adding the humectant with the formula amount, continuously stirring for 5-10 minutes, adding the surfactant with the formula amount, and continuously stirring for 20-30 minutes to obtain a mixed solution B;
(4) adding the essence with the formula amount into the mixed solution B, and stirring for 10-20 minutes to obtain a mixed solution C;
(5) and adding the pH regulator into the mixed solution C according to the formula amount, regulating the pH of the solution to 6-7, stirring for 1-2 hours, and bottling to obtain the rosemary disinfection hand sanitizer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011087480.1A CN112168729A (en) | 2020-10-13 | 2020-10-13 | Rosemary disinfection hand sanitizer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011087480.1A CN112168729A (en) | 2020-10-13 | 2020-10-13 | Rosemary disinfection hand sanitizer and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115040427A (en) * | 2022-06-07 | 2022-09-13 | 全芯生物科技(澳门)有限公司 | Hand sanitizer with slow release effect and preparation method thereof |
| CN117137820A (en) * | 2023-10-27 | 2023-12-01 | 深圳市仙鱼环保科技有限公司 | Long-acting antibacterial hand sanitizer and preparation method thereof |
-
2020
- 2020-10-13 CN CN202011087480.1A patent/CN112168729A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115040427A (en) * | 2022-06-07 | 2022-09-13 | 全芯生物科技(澳门)有限公司 | Hand sanitizer with slow release effect and preparation method thereof |
| CN115040427B (en) * | 2022-06-07 | 2024-02-02 | 全芯生物科技(澳门)有限公司 | Hand sanitizer with slow release effect and preparation method thereof |
| CN117137820A (en) * | 2023-10-27 | 2023-12-01 | 深圳市仙鱼环保科技有限公司 | Long-acting antibacterial hand sanitizer and preparation method thereof |
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