CN112933320B - 人工肺系统及其使用的方法 - Google Patents

人工肺系统及其使用的方法 Download PDF

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Publication number
CN112933320B
CN112933320B CN202110265704.1A CN202110265704A CN112933320B CN 112933320 B CN112933320 B CN 112933320B CN 202110265704 A CN202110265704 A CN 202110265704A CN 112933320 B CN112933320 B CN 112933320B
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China
Prior art keywords
oxygen
carbon dioxide
supply unit
blood
oxygen supply
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Chinese (zh)
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CN112933320A (zh
Inventor
吴忠俊
B·格里菲思
D·N·威尔斯
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University of Maryland Baltimore
Breethe Inc
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University of Maryland Baltimore
Breethe Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3666Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
    • A61M1/3667Cardiac or cardiopulmonary bypass, e.g. heart-lung machines with assisted venous return
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698Blood oxygenators with or without heat-exchangers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3666Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/02Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
    • B01D53/04Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
    • B01D53/0407Constructional details of adsorbing systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/02Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
    • B01D53/04Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
    • B01D53/0407Constructional details of adsorbing systems
    • B01D53/0446Means for feeding or distributing gases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/02Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
    • B01D53/04Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
    • B01D53/047Pressure swing adsorption
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/02Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
    • B01D53/04Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
    • B01D53/047Pressure swing adsorption
    • B01D53/053Pressure swing adsorption with storage or buffer vessel
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/02Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
    • B01D53/06Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with moving adsorbents, e.g. rotating beds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/34Chemical or biological purification of waste gases
    • B01D53/46Removing components of defined structure
    • B01D53/62Carbon oxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/08Supports for equipment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/08Supports for equipment
    • A61M2209/088Supports for equipment on the body

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Mechanical Engineering (AREA)
  • External Artificial Organs (AREA)
CN202110265704.1A 2014-11-19 2015-11-18 人工肺系统及其使用的方法 Active CN112933320B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462081747P 2014-11-19 2014-11-19
US62/081747 2014-11-19
PCT/US2015/061214 WO2016081533A1 (en) 2014-11-19 2015-11-18 Artificial lung system and its methods of use
CN201580062991.9A CN107073196B (zh) 2014-11-19 2015-11-18 人工肺系统及其使用的方法
CN202110265704.1A CN112933320B (zh) 2014-11-19 2015-11-18 人工肺系统及其使用的方法

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CN112933320B true CN112933320B (zh) 2024-05-03

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US (3) US10413655B2 (https=)
EP (3) EP4000662B1 (https=)
JP (5) JP6713992B2 (https=)
CN (2) CN112933320B (https=)
AU (4) AU2015350026B2 (https=)
DK (2) DK3220973T3 (https=)
ES (2) ES2907456T3 (https=)
WO (1) WO2016081533A1 (https=)

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CN111787965A (zh) * 2018-02-26 2020-10-16 海沃恩有限公司 控制或调节装置
US20210260266A1 (en) * 2018-06-20 2021-08-26 University Of Maryland, Baltimore System for control of a blood gas exchanger
US11318237B2 (en) 2019-02-06 2022-05-03 Separation Design Group Llc Integrated extracorporeal oxygenation and CO2 removal with ventilation system
WO2020213063A1 (ja) * 2019-04-16 2020-10-22 オリンパス株式会社 内視鏡システム
CN110124139B (zh) * 2019-05-10 2024-06-18 赣南医学院第一附属医院 Ecmo撤机时余血回收装置及方法
CN115916283B (zh) * 2020-04-07 2026-01-16 Gis风险投资公司 将溶解氧输注到静脉内流体中以为受损患者或创伤患者提供静脉血液的短期紧急充氧
CN111603626A (zh) * 2020-05-26 2020-09-01 重庆弘善医疗设备有限公司 一种使用干燥加热气体的ecmo人工膜肺机
CN112237674A (zh) * 2020-09-15 2021-01-19 安徽通灵仿生科技有限公司 微纳静脉输氧装置
JP7805626B2 (ja) * 2022-04-05 2026-01-26 株式会社三洋物産 遊技機
JP7805631B2 (ja) * 2022-04-18 2026-01-26 株式会社三洋物産 遊技機
JP7805629B2 (ja) * 2022-04-18 2026-01-26 株式会社三洋物産 遊技機
JP7805628B2 (ja) * 2022-04-18 2026-01-26 株式会社三洋物産 遊技機
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CN115445014A (zh) * 2022-10-20 2022-12-09 首都医科大学附属北京朝阳医院 氧合组件、氧合装置以及控制方法
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EP4483916A1 (en) * 2023-06-27 2025-01-01 BIOxy Med LLC-FZ Combined blood pump and oxygenator system
CN121335723A (zh) * 2023-06-29 2026-01-13 迈奎特心肺有限公司 体外膜肺氧合系统
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DE19702098A1 (de) * 1997-01-22 1998-07-23 Horus Medizinische Artikel Und Mobile Herz-Lungenmaschine
CA2269555A1 (en) * 1997-10-01 1999-04-08 Invacare Corporation Apparatus and method for forming oxygen-enriched gas and compression thereof for high-pressure mobile storage utilization
WO2002043792A1 (en) * 2000-11-28 2002-06-06 Art Of Xen Limited Gas exchange
WO2005028002A1 (en) * 2003-09-22 2005-03-31 Dudu Haimovich Blood oxygenation system with single lumen catheter
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GB0607410D0 (en) * 2006-04-13 2006-05-24 Haemair Ltd Blood/air mass exchange apparatus
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JP7766659B2 (ja) 2025-11-10
JP2024009921A (ja) 2024-01-23
CN107073196A (zh) 2017-08-18
US20170252505A1 (en) 2017-09-07
EP4378496A3 (en) 2024-07-10
AU2025204238A1 (en) 2025-06-26
US20240050637A1 (en) 2024-02-15
WO2016081533A1 (en) 2016-05-26
EP4378496A2 (en) 2024-06-05
AU2020267243B2 (en) 2022-12-01
JP2017538485A (ja) 2017-12-28
AU2023201261B2 (en) 2025-03-06
US10413655B2 (en) 2019-09-17
EP3220973A1 (en) 2017-09-27
ES2907456T3 (es) 2022-04-25
EP3220973B1 (en) 2022-01-05
JP2022062721A (ja) 2022-04-20
CN112933320A (zh) 2021-06-11
JP7010997B2 (ja) 2022-01-26
US20200001000A1 (en) 2020-01-02
AU2015350026A1 (en) 2017-07-06
EP4000662B1 (en) 2024-02-21
EP3220973A4 (en) 2018-05-23
AU2023201261A1 (en) 2023-04-06
JP2020168389A (ja) 2020-10-15
AU2015350026B2 (en) 2020-08-13
DK4000662T3 (da) 2024-03-18
CN107073196B (zh) 2021-03-30
JP6713992B2 (ja) 2020-06-24
AU2020267243A1 (en) 2020-12-10
JP7367083B2 (ja) 2023-10-23
JP2026021416A (ja) 2026-02-10
DK3220973T3 (da) 2022-03-14
US11638778B2 (en) 2023-05-02
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ES2975684T3 (es) 2024-07-11

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