CN112867514A - 提供药物微贮库的接触转移的管腔内可扩张导管的涂层 - Google Patents

提供药物微贮库的接触转移的管腔内可扩张导管的涂层 Download PDF

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Publication number
CN112867514A
CN112867514A CN201980068468.5A CN201980068468A CN112867514A CN 112867514 A CN112867514 A CN 112867514A CN 201980068468 A CN201980068468 A CN 201980068468A CN 112867514 A CN112867514 A CN 112867514A
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CN
China
Prior art keywords
coating
catheter
micro
reservoirs
glycero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980068468.5A
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English (en)
Chinese (zh)
Inventor
迈克尔·托马斯·阿勒林
罗纳德·克尼希·亚马莫托
罗伯特·约翰·埃利克
阮婷推
约翰·爱德温·舒尔茨
耶勒·朱尔珍·佐特胡特
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Ma Med Alliance Sa
Original Assignee
Ma Med Alliance Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/160,888 external-priority patent/US11406742B2/en
Application filed by Ma Med Alliance Sa filed Critical Ma Med Alliance Sa
Publication of CN112867514A publication Critical patent/CN112867514A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1027—Making of balloon catheters
    • A61M25/1029—Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A61L2300/222—Steroids, e.g. corticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/63—Crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M2025/0024—Expandable catheters or sheaths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1027—Making of balloon catheters
    • A61M25/1029—Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril
    • A61M2025/1031—Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
CN201980068468.5A 2018-10-15 2019-10-14 提供药物微贮库的接触转移的管腔内可扩张导管的涂层 Pending CN112867514A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/160,888 2018-10-15
US16/160,888 US11406742B2 (en) 2014-07-18 2018-10-15 Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
PCT/US2019/056127 WO2020081455A1 (en) 2018-10-15 2019-10-14 Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs

Publications (1)

Publication Number Publication Date
CN112867514A true CN112867514A (zh) 2021-05-28

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ID=68426853

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980068468.5A Pending CN112867514A (zh) 2018-10-15 2019-10-14 提供药物微贮库的接触转移的管腔内可扩张导管的涂层

Country Status (9)

Country Link
EP (1) EP3866869A1 (ja)
JP (2) JP7449298B2 (ja)
KR (1) KR20210077697A (ja)
CN (1) CN112867514A (ja)
AU (1) AU2019362775A1 (ja)
BR (1) BR112021007192A2 (ja)
CA (1) CA3114461A1 (ja)
MX (1) MX2021004238A (ja)
WO (1) WO2020081455A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114870096A (zh) * 2022-07-08 2022-08-09 上海申淇医疗科技有限公司 球囊导管涂层及其制备方法、球囊导管
CN116099108A (zh) * 2021-11-09 2023-05-12 上海博脉安医疗科技有限公司 一种药物涂层、药物洗脱球囊导管及其制备方法
CN116492513A (zh) * 2023-05-30 2023-07-28 武汉天楚生物科技有限公司 一种母猪受孕自动输精管用温敏蜡材料及其制备方法
WO2024099433A1 (zh) * 2022-11-11 2024-05-16 凯诺威医疗科技(武汉)有限公司 一种药涂球囊涂覆液、涂层材料、药涂球囊、制备方法及应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022223090A1 (en) * 2021-04-19 2022-10-27 Rontis Hellas S.A. Drug delivery system for medical devices

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US20080255509A1 (en) * 2006-11-20 2008-10-16 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US20120165786A1 (en) * 2010-06-30 2012-06-28 Chappa Ralph A Lipid coating for medical devices delivering bioactive agent
US20120315300A1 (en) * 2010-01-22 2012-12-13 Envision Scientific Private Limited Insertable medical devices with a porous bed for delivering nano-carriers to a target site and methods of preparing the same
CN102883753A (zh) * 2010-03-25 2013-01-16 路通医疗股份有限公司 用于医疗设备的释药涂层
WO2014143048A1 (en) * 2013-03-15 2014-09-18 Abbott Cardiovascular Systems, Inc. Tissue adhesive coatings for drug balloon
US20140350464A1 (en) * 2011-07-08 2014-11-27 Cardionovum Sp.Z.O.O. Balloon catheter with a sirolimus coated catheter balloon for controlled release of sirolimus
EP2958607A1 (en) * 2013-05-02 2015-12-30 Cardionovum GmbH Balloon surface coating
CN107073178A (zh) * 2014-07-18 2017-08-18 M.A.医学联合公司 提供药物微贮库的接触转移的管腔内可扩张导管的涂层

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Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080255509A1 (en) * 2006-11-20 2008-10-16 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US20120315300A1 (en) * 2010-01-22 2012-12-13 Envision Scientific Private Limited Insertable medical devices with a porous bed for delivering nano-carriers to a target site and methods of preparing the same
CN102883753A (zh) * 2010-03-25 2013-01-16 路通医疗股份有限公司 用于医疗设备的释药涂层
US20120165786A1 (en) * 2010-06-30 2012-06-28 Chappa Ralph A Lipid coating for medical devices delivering bioactive agent
US20140350464A1 (en) * 2011-07-08 2014-11-27 Cardionovum Sp.Z.O.O. Balloon catheter with a sirolimus coated catheter balloon for controlled release of sirolimus
WO2014143048A1 (en) * 2013-03-15 2014-09-18 Abbott Cardiovascular Systems, Inc. Tissue adhesive coatings for drug balloon
EP2958607A1 (en) * 2013-05-02 2015-12-30 Cardionovum GmbH Balloon surface coating
CN107073178A (zh) * 2014-07-18 2017-08-18 M.A.医学联合公司 提供药物微贮库的接触转移的管腔内可扩张导管的涂层

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116099108A (zh) * 2021-11-09 2023-05-12 上海博脉安医疗科技有限公司 一种药物涂层、药物洗脱球囊导管及其制备方法
WO2023083086A1 (zh) * 2021-11-09 2023-05-19 上海博脉安医疗科技有限公司 一种药物涂层、药物洗脱球囊导管及其制备方法
CN114870096A (zh) * 2022-07-08 2022-08-09 上海申淇医疗科技有限公司 球囊导管涂层及其制备方法、球囊导管
CN114870096B (zh) * 2022-07-08 2022-11-04 上海申淇医疗科技有限公司 球囊导管涂层及其制备方法、球囊导管
CN116271254A (zh) * 2022-07-08 2023-06-23 上海申淇医疗科技有限公司 球囊导管涂层及其制备方法、球囊导管
CN116271254B (zh) * 2022-07-08 2024-04-02 上海申淇医疗科技有限公司 球囊导管涂层及其制备方法、球囊导管
WO2024099433A1 (zh) * 2022-11-11 2024-05-16 凯诺威医疗科技(武汉)有限公司 一种药涂球囊涂覆液、涂层材料、药涂球囊、制备方法及应用
CN116492513A (zh) * 2023-05-30 2023-07-28 武汉天楚生物科技有限公司 一种母猪受孕自动输精管用温敏蜡材料及其制备方法
CN116492513B (zh) * 2023-05-30 2023-11-03 武汉天楚生物科技有限公司 一种母猪受孕自动输精管用温敏蜡材料及其制备方法

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JP2024026639A (ja) 2024-02-28
EP3866869A1 (en) 2021-08-25
BR112021007192A2 (pt) 2021-07-20
CA3114461A1 (en) 2020-04-23
WO2020081455A1 (en) 2020-04-23
KR20210077697A (ko) 2021-06-25
JP7449298B2 (ja) 2024-03-13
MX2021004238A (es) 2021-05-27
AU2019362775A1 (en) 2021-04-15
JP2022512006A (ja) 2022-02-01

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