CN112773765A - 治疗普拉德-威利综合征的方法 - Google Patents

治疗普拉德-威利综合征的方法 Download PDF

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Publication number
CN112773765A
CN112773765A CN202110278199.4A CN202110278199A CN112773765A CN 112773765 A CN112773765 A CN 112773765A CN 202110278199 A CN202110278199 A CN 202110278199A CN 112773765 A CN112773765 A CN 112773765A
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CN
China
Prior art keywords
carbetocin
day
substituted
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110278199.4A
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English (en)
Chinese (zh)
Inventor
帕斯卡尔·丹格拉斯
迈克尔·雷迪
保罗·考纳尔
苏达考迪·阿拉加萨米
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Firelink
Ferring BV
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Firelink
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Publication date
Application filed by Firelink filed Critical Firelink
Publication of CN112773765A publication Critical patent/CN112773765A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202110278199.4A 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法 Pending CN112773765A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462052957P 2014-09-19 2014-09-19
US62/052,957 2014-09-19
CN201580049147.2A CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580049147.2A Division CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Publications (1)

Publication Number Publication Date
CN112773765A true CN112773765A (zh) 2021-05-11

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110278199.4A Pending CN112773765A (zh) 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法
CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Family Applications After (1)

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US (3) US10441627B2 (enExample)
EP (2) EP3193907B1 (enExample)
JP (3) JP6599447B2 (enExample)
CN (2) CN112773765A (enExample)
CA (1) CA2957224A1 (enExample)
DK (1) DK3666258T3 (enExample)
ES (2) ES2970059T3 (enExample)
FI (1) FI3666258T3 (enExample)
HR (1) HRP20240166T1 (enExample)
HU (1) HUE065829T2 (enExample)
LT (1) LT3666258T (enExample)
PL (1) PL3666258T3 (enExample)
PT (1) PT3666258T (enExample)
RS (1) RS65144B1 (enExample)
SI (1) SI3666258T1 (enExample)
WO (1) WO2016044131A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10441627B2 (en) * 2014-09-19 2019-10-15 Ferring B.V. Method of treating prader-willi syndrome
US20190135859A1 (en) 2017-08-11 2019-05-09 Ferring B.V. Method of manufacturing a pharmaceutical composition
KR102704660B1 (ko) 2017-08-11 2024-09-06 훼링 비.브이. 약학적 조성물의 제조 방법
US10736894B2 (en) 2018-02-15 2020-08-11 Ovid Therapeutics Inc. Methods of treating developmental syndromes with PDE10A inhibitors
EP3852723B1 (en) * 2018-09-20 2025-11-05 ACADIA Pharmaceuticals Inc. Stable intranasal formulations of carbetocin
AU2019345313A1 (en) * 2018-09-20 2021-03-18 Levo Therapeutics, Inc. Carbetocin drug product and process for preparing same
WO2022133198A1 (en) * 2020-12-18 2022-06-23 The General Hospital Corporation Probiotics compositions and method of using the same to enhance growth and social function in children
WO2022200568A1 (en) 2021-03-26 2022-09-29 Ot4B Treatment of dysphagia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7544662B2 (en) 1993-06-17 2009-06-09 Carle Development Foundation Polypeptides useful for appetite suppression
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
US6894026B1 (en) 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
US9023793B2 (en) 2006-09-29 2015-05-05 Retrophin, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
NZ581452A (en) 2007-06-07 2012-11-30 Kyalin Bioscience Inc Intranasal carbetocin formulations and methods for the treatment of autism
WO2009033770A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Calcitonin c-terminal flanking peptide for use as a therapeutic agent
KR20100057641A (ko) 2007-09-11 2010-05-31 몬도바이오테크 래보래토리즈 아게 인터메딘 47 및 53 펩티드의 치료적 용도
US20100204150A1 (en) 2007-09-11 2010-08-12 Dorian Bevec Use of a peptide as a therapeutic agent
WO2009033820A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
HRP20140716T1 (hr) * 2008-03-31 2014-08-29 Ferring B.V. Analozi oksitocina
NZ590732A (en) 2008-07-18 2012-09-28 Zafgen Inc Methods of treating an overweight or obese subject using fumagillin
US20120108510A1 (en) 2010-05-20 2012-05-03 Emory University Methods of improving behavioral therapies
ES2595251T3 (es) 2010-05-25 2016-12-28 Inserm - Institut National De La Santé Et De La Recherche Médicale Métodos y composición farmacéutica para el tratamiento de un trastorno alimentario con inicio temprano en un paciente
WO2012149472A2 (en) 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
CN104870466B (zh) 2012-12-21 2018-05-18 霍夫曼-拉罗奇有限公司 作为催产素激动剂的肽
CA2949173A1 (en) 2014-06-03 2015-12-10 Caterina Bissantz Peptides as oxytocin agonists
CR20160562A (es) 2014-06-06 2017-01-06 Hoffmann La Roche Péptidos como agonistas de la oxitocina
CN106573958A (zh) 2014-08-07 2017-04-19 豪夫迈·罗氏有限公司 用于制备催产素类似物的方法
US10441627B2 (en) * 2014-09-19 2019-10-15 Ferring B.V. Method of treating prader-willi syndrome

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

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Publication number Publication date
HUE065829T2 (hu) 2024-06-28
JP2017532316A (ja) 2017-11-02
EP3666258A1 (en) 2020-06-17
JP2021098745A (ja) 2021-07-01
SI3666258T1 (sl) 2024-04-30
EP3193907B1 (en) 2020-01-01
RS65144B1 (sr) 2024-02-29
WO2016044131A1 (en) 2016-03-24
ES2970059T3 (es) 2024-05-24
EP3666258B1 (en) 2023-11-15
HRP20240166T1 (hr) 2024-04-26
LT3666258T (lt) 2024-01-10
CN106714819A (zh) 2017-05-24
US10441627B2 (en) 2019-10-15
DK3666258T3 (da) 2024-02-05
JP6599447B2 (ja) 2019-10-30
US20240082344A1 (en) 2024-03-14
EP3193907A1 (en) 2017-07-26
JP2020019790A (ja) 2020-02-06
CA2957224A1 (en) 2016-03-24
PL3666258T3 (pl) 2024-04-08
JP6921154B2 (ja) 2021-08-18
PT3666258T (pt) 2024-02-01
ES2775425T3 (es) 2020-07-27
FI3666258T3 (fi) 2024-02-09
US20200129584A1 (en) 2020-04-30
US20170326200A1 (en) 2017-11-16

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