CN112773765A - 治疗普拉德-威利综合征的方法 - Google Patents

治疗普拉德-威利综合征的方法 Download PDF

Info

Publication number
CN112773765A
CN112773765A CN202110278199.4A CN202110278199A CN112773765A CN 112773765 A CN112773765 A CN 112773765A CN 202110278199 A CN202110278199 A CN 202110278199A CN 112773765 A CN112773765 A CN 112773765A
Authority
CN
China
Prior art keywords
carbetocin
day
substituted
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110278199.4A
Other languages
English (en)
Chinese (zh)
Inventor
帕斯卡尔·丹格拉斯
迈克尔·雷迪
保罗·考纳尔
苏达考迪·阿拉加萨米
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Firelink
Ferring BV
Original Assignee
Firelink
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firelink filed Critical Firelink
Publication of CN112773765A publication Critical patent/CN112773765A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202110278199.4A 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法 Pending CN112773765A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462052957P 2014-09-19 2014-09-19
US62/052,957 2014-09-19
CN201580049147.2A CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580049147.2A Division CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Publications (1)

Publication Number Publication Date
CN112773765A true CN112773765A (zh) 2021-05-11

Family

ID=54238564

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110278199.4A Pending CN112773765A (zh) 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法
CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Country Status (16)

Country Link
US (3) US10441627B2 (enExample)
EP (2) EP3666258B1 (enExample)
JP (3) JP6599447B2 (enExample)
CN (2) CN112773765A (enExample)
CA (1) CA2957224A1 (enExample)
DK (1) DK3666258T3 (enExample)
ES (2) ES2775425T3 (enExample)
FI (1) FI3666258T3 (enExample)
HR (1) HRP20240166T1 (enExample)
HU (1) HUE065829T2 (enExample)
LT (1) LT3666258T (enExample)
PL (1) PL3666258T3 (enExample)
PT (1) PT3666258T (enExample)
RS (1) RS65144B1 (enExample)
SI (1) SI3666258T1 (enExample)
WO (1) WO2016044131A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2957224A1 (en) * 2014-09-19 2016-03-24 Ferring B.V. Method of treating prader-willi syndrome
US10981955B2 (en) 2017-08-11 2021-04-20 Ferring B.V. Method of manufacturing a pharmaceutical composition
US20190135859A1 (en) 2017-08-11 2019-05-09 Ferring B.V. Method of manufacturing a pharmaceutical composition
US10736894B2 (en) 2018-02-15 2020-08-11 Ovid Therapeutics Inc. Methods of treating developmental syndromes with PDE10A inhibitors
AU2019345313A1 (en) 2018-09-20 2021-03-18 Levo Therapeutics, Inc. Carbetocin drug product and process for preparing same
CN112839632A (zh) * 2018-09-20 2021-05-25 莱沃疗法公司 稳定的鼻内卡贝缩宫素制剂
US20240050494A1 (en) * 2020-12-18 2024-02-15 The General Hospital Corporation Probiotics compositions and method of using the same to enhance growth and social function in children
PL4313106T3 (pl) 2021-03-26 2025-09-01 Ot4B Leczenie dysfagii

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7544662B2 (en) 1993-06-17 2009-06-09 Carle Development Foundation Polypeptides useful for appetite suppression
US6894026B1 (en) 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
WO2008150305A1 (en) 2007-06-07 2008-12-11 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
US9023793B2 (en) 2006-09-29 2015-05-05 Retrophin, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
CA2699169A1 (en) 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Therapeutic uses of intermedin 47 and 53 peptides
CA2704724A1 (en) 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag 5use of a peptide as a therapeutic agent
WO2009033820A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2197463A2 (en) 2007-09-11 2010-06-23 Mondobiotech Laboratories AG Use of rgdspasskp and optionally angiotensin ii as therapeutic agents in the treatment of eg s. pneumoniae infections
HRP20140716T1 (hr) 2008-03-31 2014-08-29 Ferring B.V. Analozi oksitocina
CA2731020A1 (en) 2008-07-18 2010-01-21 Zafgen, Inc. Use of antiangiogenic fumagillins in the treatment of obesity
US20120108510A1 (en) 2010-05-20 2012-05-03 Emory University Methods of improving behavioral therapies
US8853158B2 (en) 2010-05-25 2014-10-07 Institut National De La Santé Et De La Recherche Médicale (Inserm) Methods for the treatment of a feeding disorder with onset during neonate development using an agonist of the oxytocin receptor
WO2012149472A2 (en) 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
EA026687B1 (ru) 2012-12-21 2017-05-31 Ф. Хоффманн-Ля Рош Аг Пептиды в качестве агонистов окситоцина
EA030091B1 (ru) 2014-06-03 2018-06-29 Ф. Хоффманн-Ля Рош Аг Пептиды, выполняющие роль агонистов окситоцина
CR20160562A (es) 2014-06-06 2017-01-06 Hoffmann La Roche Péptidos como agonistas de la oxitocina
SI3177635T1 (sl) 2014-08-07 2019-01-31 F. Hoffmann-La Roche Ag Postopki za pripravo analogov oksitocina
CA2957224A1 (en) * 2014-09-19 2016-03-24 Ferring B.V. Method of treating prader-willi syndrome

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

Also Published As

Publication number Publication date
JP6921154B2 (ja) 2021-08-18
FI3666258T3 (fi) 2024-02-09
JP2021098745A (ja) 2021-07-01
CN106714819A (zh) 2017-05-24
HUE065829T2 (hu) 2024-06-28
US20200129584A1 (en) 2020-04-30
US20240082344A1 (en) 2024-03-14
PT3666258T (pt) 2024-02-01
ES2775425T3 (es) 2020-07-27
JP2020019790A (ja) 2020-02-06
SI3666258T1 (sl) 2024-04-30
RS65144B1 (sr) 2024-02-29
EP3666258A1 (en) 2020-06-17
EP3666258B1 (en) 2023-11-15
CA2957224A1 (en) 2016-03-24
US10441627B2 (en) 2019-10-15
US20170326200A1 (en) 2017-11-16
JP6599447B2 (ja) 2019-10-30
ES2970059T3 (es) 2024-05-24
WO2016044131A1 (en) 2016-03-24
PL3666258T3 (pl) 2024-04-08
DK3666258T3 (da) 2024-02-05
HRP20240166T1 (hr) 2024-04-26
JP2017532316A (ja) 2017-11-02
EP3193907A1 (en) 2017-07-26
EP3193907B1 (en) 2020-01-01
LT3666258T (lt) 2024-01-10

Similar Documents

Publication Publication Date Title
JP6921154B2 (ja) プラダー・ウィリー症候群を治療する方法
AU2013205648B2 (en) Combination treatment
US10092564B2 (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
US20200276136A1 (en) Method of treating selected patient population experiencing dravet syndrome
US20190247333A1 (en) Method of reduction in convulsive seizure frequency
EP3930841A1 (en) A formulation for improving seizure control
WO2019067413A1 (en) USE OF A FENFLURAMINE FORMULATION TO REDUCE THE NUMBER AND FREQUENCIES OF CONVULSIVE CRISES IN PATIENT POPULATIONS
US20220151960A1 (en) Treatment of symptoms associated with female gastroparesis
MX2014002125A (es) Tratamiento de sintomas asociados a gastroparesia femenina.
IL303006A (en) Use of pyridofidine and analogues for the treatment of Rett syndrome
PH12015500915B1 (en) Uses of bremelanotide in therapy for female sexual dysfunction
WO2025255116A1 (en) Methods of treatment for opioid-induced ventilatory depression and muscle rigidity
US8680145B1 (en) Compositions and methods for treatment of fear of medical procedures
HK40081935A (en) Treatment of amyotrophic lateral sclerosis
JP2006117569A (ja) ステロイド依存性あるいはステロイド抵抗性潰瘍性大腸炎治療薬

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination