JP6599447B2 - プラダー・ウィリー症候群を治療する方法 - Google Patents

プラダー・ウィリー症候群を治療する方法 Download PDF

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JP6599447B2
JP6599447B2 JP2017515228A JP2017515228A JP6599447B2 JP 6599447 B2 JP6599447 B2 JP 6599447B2 JP 2017515228 A JP2017515228 A JP 2017515228A JP 2017515228 A JP2017515228 A JP 2017515228A JP 6599447 B2 JP6599447 B2 JP 6599447B2
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pharmaceutical composition
carbetocin
composition according
substituted
alkyl
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JP2017532316A5 (enExample
JP2017532316A (ja
Inventor
デングラス,パスカル
レイディ,マイケル
コーナー,ポール
アラガーサミィ,スダーコディ
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フェリング ベスローテン フェンノートシャップ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017515228A 2014-09-19 2015-09-14 プラダー・ウィリー症候群を治療する方法 Active JP6599447B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019181930A JP6921154B2 (ja) 2014-09-19 2019-10-02 プラダー・ウィリー症候群を治療する方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462052957P 2014-09-19 2014-09-19
US62/052,957 2014-09-19
PCT/US2015/049911 WO2016044131A1 (en) 2014-09-19 2015-09-14 Method of treating prader-willi syndrome

Related Child Applications (1)

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JP2019181930A Division JP6921154B2 (ja) 2014-09-19 2019-10-02 プラダー・ウィリー症候群を治療する方法

Publications (3)

Publication Number Publication Date
JP2017532316A JP2017532316A (ja) 2017-11-02
JP2017532316A5 JP2017532316A5 (enExample) 2018-09-20
JP6599447B2 true JP6599447B2 (ja) 2019-10-30

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Application Number Title Priority Date Filing Date
JP2017515228A Active JP6599447B2 (ja) 2014-09-19 2015-09-14 プラダー・ウィリー症候群を治療する方法
JP2019181930A Active JP6921154B2 (ja) 2014-09-19 2019-10-02 プラダー・ウィリー症候群を治療する方法
JP2021041334A Pending JP2021098745A (ja) 2014-09-19 2021-03-15 プラダー・ウィリー症候群を治療する方法

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JP2019181930A Active JP6921154B2 (ja) 2014-09-19 2019-10-02 プラダー・ウィリー症候群を治療する方法
JP2021041334A Pending JP2021098745A (ja) 2014-09-19 2021-03-15 プラダー・ウィリー症候群を治療する方法

Country Status (16)

Country Link
US (3) US10441627B2 (enExample)
EP (2) EP3666258B1 (enExample)
JP (3) JP6599447B2 (enExample)
CN (2) CN112773765A (enExample)
CA (1) CA2957224A1 (enExample)
DK (1) DK3666258T3 (enExample)
ES (2) ES2970059T3 (enExample)
FI (1) FI3666258T3 (enExample)
HR (1) HRP20240166T1 (enExample)
HU (1) HUE065829T2 (enExample)
LT (1) LT3666258T (enExample)
PL (1) PL3666258T3 (enExample)
PT (1) PT3666258T (enExample)
RS (1) RS65144B1 (enExample)
SI (1) SI3666258T1 (enExample)
WO (1) WO2016044131A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20240166T1 (hr) 2014-09-19 2024-04-26 Ferring B.V. Postupak liječenja prader-willijevog sindroma
WO2019032946A1 (en) 2017-08-11 2019-02-14 Ferring B.V. PROCESS FOR PRODUCING OXYTOCIN
US10981955B2 (en) 2017-08-11 2021-04-20 Ferring B.V. Method of manufacturing a pharmaceutical composition
US10736894B2 (en) 2018-02-15 2020-08-11 Ovid Therapeutics Inc. Methods of treating developmental syndromes with PDE10A inhibitors
US20200093884A1 (en) * 2018-09-20 2020-03-26 Mark C. Manning Stable intranasal formulations of carbetocin
WO2020061416A1 (en) * 2018-09-20 2020-03-26 Levo Therapeutics, Inc. Carbetocin drug product and process for preparing same
CN116981468A (zh) * 2020-12-18 2023-10-31 通用医疗公司 益生菌组合物以及使用其促进儿童生长和社交功能的方法
CA3214303A1 (en) * 2021-03-26 2022-09-29 Ot4B Treatment of dysphagia

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7544662B2 (en) 1993-06-17 2009-06-09 Carle Development Foundation Polypeptides useful for appetite suppression
US6894026B1 (en) 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
US9023793B2 (en) 2006-09-29 2015-05-05 Retrophin, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
US20100311655A1 (en) 2007-06-07 2010-12-09 Mdrna, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
AU2008303955A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of melanocyte-stimulating hormone release-inhibiting factor as a therapeutic agent in the treatment of Pseudomonas aeruginosa infection
WO2009033820A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
WO2009040020A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Amylin as a therapeutic agent
KR20100061680A (ko) 2007-09-11 2010-06-08 몬도바이오테크 래보래토리즈 아게 치료제로서의 gly-pro-glu-oh(gpe)의 용도
DK2260053T3 (da) * 2008-03-31 2014-06-23 Ferring Bv Oxytocin-analoger
US8865746B2 (en) 2008-07-18 2014-10-21 Zafgen, Inc. Methods of treating an overweight or obese subject
TWI463990B (zh) * 2009-09-21 2014-12-11 Ferring Bv 催產素受體促進劑
US20120108510A1 (en) 2010-05-20 2012-05-03 Emory University Methods of improving behavioral therapies
WO2011147889A1 (en) * 2010-05-25 2011-12-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient
JO3400B1 (ar) * 2010-09-30 2019-10-20 Ferring Bv مركب صيدلاني من كاربيتوسين
WO2012149472A2 (en) 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
CN104870466B (zh) * 2012-12-21 2018-05-18 霍夫曼-拉罗奇有限公司 作为催产素激动剂的肽
KR20150108384A (ko) 2013-01-17 2015-09-25 에프. 호프만-라 로슈 아게 중추신경계 질병의 치료를 위한 옥시토신 수용체 작용제
AU2015270723A1 (en) 2014-06-03 2016-11-17 F. Hoffmann-La Roche Ag Peptides as oxytocin agonists
CR20160562A (es) 2014-06-06 2017-01-06 Hoffmann La Roche Péptidos como agonistas de la oxitocina
KR20170040231A (ko) 2014-08-07 2017-04-12 에프. 호프만-라 로슈 아게 옥시토신 유사체의 제조 방법
HRP20240166T1 (hr) * 2014-09-19 2024-04-26 Ferring B.V. Postupak liječenja prader-willijevog sindroma

Also Published As

Publication number Publication date
CA2957224A1 (en) 2016-03-24
CN112773765A (zh) 2021-05-11
LT3666258T (lt) 2024-01-10
US20200129584A1 (en) 2020-04-30
DK3666258T3 (da) 2024-02-05
JP6921154B2 (ja) 2021-08-18
ES2775425T3 (es) 2020-07-27
PL3666258T3 (pl) 2024-04-08
EP3666258A1 (en) 2020-06-17
WO2016044131A1 (en) 2016-03-24
US10441627B2 (en) 2019-10-15
EP3193907A1 (en) 2017-07-26
JP2017532316A (ja) 2017-11-02
HUE065829T2 (hu) 2024-06-28
US20170326200A1 (en) 2017-11-16
HRP20240166T1 (hr) 2024-04-26
CN106714819A (zh) 2017-05-24
FI3666258T3 (fi) 2024-02-09
ES2970059T3 (es) 2024-05-24
PT3666258T (pt) 2024-02-01
EP3193907B1 (en) 2020-01-01
JP2020019790A (ja) 2020-02-06
US20240082344A1 (en) 2024-03-14
SI3666258T1 (sl) 2024-04-30
EP3666258B1 (en) 2023-11-15
RS65144B1 (sr) 2024-02-29
JP2021098745A (ja) 2021-07-01

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